Journal of Natural Medicines

Papers
(The median citation count of Journal of Natural Medicines is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Correction: Evaluation of rooting characteristics of Ephedra cuttings by anatomy and promising strain selection based on rooting characteristics and alkaloid content29
Ecological and pharmacognostical characteristics in Ephedra saxatilis in the Yarlung Zangbo River Valley of southeastern Tibetan Plateau, China25
Identification of intracellular activation mechanism of rhamnogalacturonan-I type polysaccharide purified from Panax ginseng leaves in macrophages and roles of component sugar chains on activity23
Eleven new C19-diterpenoid alkaloids from Delphinium elatum cv. Pacific Giant21
Apoptosis-inducing activity of a steroidal glycoside from Allium chinense G. Don. bulbs in human small-cell lung cancer cells via mitochondrial dysfunction and ER stress18
Chlorinated illudalane sequiterpenoids from Saxiglossum angustissimum18
Three new meroterpenoids from Sargassum macrocarpum and their inhibitory activity against amyloid β aggregation17
Two new clerodane diterpenoids and a new pyran-2-one derivative with anti-neuroinflammatory activities from Croton crassifolius17
Diosmetin alleviates osteoarthritis through modulating the polarization of macrophages by inhibiting the PI3K/Akt signaling pathway15
Multi-omics analysis reveals tissue-specific biosynthesis and accumulation of diterpene alkaloids in Aconitum japonicum15
Heating or ginger extract reduces the content of Pinellia ternata lectin in the raphides of Pinellia tuber15
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells14
Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder14
Angelic acid triggers ferroptosis in colorectal cancer cells via targeting and impairing NRF2 protein stability14
Lateral flow immunoassay for small-molecules detection in phytoproducts: a review13
Identification of a diarylpentanoid-producing polyketide synthase in the biosynthesis of 2-(2-phenylethyl)chromones in agarwood12
A feruloylated acylglycerol isolated from Wikstroemia pilosa and its distribution in ten plants of Wikstroemia species12
Chukranoids A–I, isopimarane diterpenoids from Chukrasia velutina12
Macrocyclizing-thioesterases in bacterial non-ribosomal peptide biosynthesis12
Panaxindole, a novel indole alkaloid N-glucoside from the leaves of Panax vietnamensis Ha et Grushv. (Vietnamese ginseng)12
Application of the relative molar sensitivity method using GC-FID to quantify safranal in saffron (Crocus sativus L.)12
Anti-trypanosomal screening of Salvadoran flora12
Four new acylated glycosidic acid methyl esters and a new glycosidic acid from Ipomoea lacunosa seeds12
Scutellaria Root extract-induced hepatocytotoxicity can be controlled by regulating its baicalin content11
Ginsenoside Rh3-induced neurotoxicity involving the IP3R-Ca2+/NOX2/NF-κB signaling pathways11
Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes11
Mechanism study of the effects of astragaloside IV and quercetin on idiopathic pulmonary fibrosis11
Quality assessment of Rheum species cultivated in Japan by focusing on M2 polarization of microglia11
HPLC analysis of ammonium glycyrrhizate listed in the European, United States, and Japanese Pharmacopoeias under reported and modified conditions: revision of the peak assignment for 18α-glycyrrhizin 11
Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy10
Polysaccharides from Lentinus edodes prevent acquired drug resistance to docetaxel in prostate cancer cells by decreasing the TGF-β1 secretion of cancer-associated fibroblasts10
Meroterpenoids with BACE1-inhibitory activity from the fruiting bodies of Suillus bovinus and Boletinus cavipes10
Seven undescribed meroterpenoids from Sargassum siliquastrum and their inhibitory activity against amyloid β aggregation10
Phenanthroindolizine alkaloids from Boehmeria sieboldiana leaves exhibit cytotoxicity against human cancer cell lines10
17β-neriifolin from unripe fruits of Cerbera manghas suppressed cell proliferation via the inhibition of HOXA9-dependent transcription and the induction of apoptosis in the human AML cell line THP-110
Correction: Anti-influenza A virus activity of flavonoids in vitro: a structure–activity relationship10
Development of a determination method for quality control markers utilizing metabolic profiling and its application on processed Zingiber officinale Roscoe rhizome10
Pharmacokinetics of seven major components in Aβ1-42-treated rats after oral administration of an aqueous extract of Curculiginis Rhizoma and Epimedii Folium10
Dendrobium huoshanense polysaccharide inhibits NSCLC proliferation and immune evasion via FXR1-IL-35 axis signaling pathway9
Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction9
Ergot alkaloids in sclerotia collected in Japan: synthetic profiles and induction of apoptosis by Clavine-type compounds9
Correction to: Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients9
Germacrone, isolated from Curcuma wenyujin, inhibits melanin synthesis through the regulation of the MAPK signaling pathway9
Daphnane diterpenoid orthoesters with an odd-numbered aliphatic side chain from Daphne pedunculata9
Promotion of neurite outgrowth by 3,5,7,3ʹ,4ʹ-pentamethoxyflavone is mediated through ERK signaling pathway in Neuro2a cells9
Five pimarane diterpenoids from Kaempferia champasakensis and their cytotoxic activities8
Crocetin alleviates the caerulein-induced apoptosis and inflammation in AR42J cells by activating SIRT1 via NF-κB8
Chaihu Guizhi Ganjiang Decoction ameliorates chronic pancreatitis by modulating the SK1/S1P signaling pathway8
Ergostane-type steroids from mushrooms of Pleurotus genus8
Celastrus orbiculatus extract suppresses gastric cancer stem cells through the TGF-β/Smad signaling pathway8
Linderapyrone analogue LPD-01 as a cancer treatment agent by targeting importin78
Inhibitory functions of cornuside on TGFBIp-mediated septic responses8
Rhein alleviates advanced glycation end products (AGEs)-induced inflammatory injury of diabetic cardiomyopathy in vitro and in vivo models8
Lanceolanone A, a new biflavanone, and a chalcone glucoside from the flower heads of Coreopsis lanceolata and their aldose reductase inhibitory activity and AMPK activation8
Andrographolide anti-proliferation and metastasis of hepatocellular carcinoma through LncRNA MIR22HG regulation8
Investigations of AGEs’ inhibitory and nephroprotective potential of ursolic acid towards reduction of diabetic complications8
Ingenol mebutate inhibits the growth of pancreatic cancer cells in vitro via STING with an efficacy comparable to that of clinically used anticancer agents8
Integrative informatics analysis identifies that ginsenoside Re improves renal fibrosis through regulation of autophagy8
Alkylphthalides with intracellular triglyceride metabolism-promoting activity from the rhizomes of Cnidium officinale Makino8
Inhibitory effects of senkyuchachosan on SARS-CoV-2 papain-like protease activity in vitro7
2(3H)-Dihydrofranolactone metabolites from Pleosporales sp. NUH322 as anti-amyotrophic lateral sclerosis drugs7
The pleiotropic anti-cancer, antiviral, and anti-neuro-immunomodulatory role of methanolic neem bark extract7
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose7
Anti-allergic actions and pharmacokinetics of orally administered 18α-glycyrrhetinic acid and 18β-glycyrrhetinic acid in mice7
Shorter and more efficient pretreatment for germination of perilla mericarps7
Optimal harvest-time to maximize the annual camptothecin production by Ophiorrhiza pumila in a plant factory with artificial light7
Identification and characterization of organic and glycosidic acids in the crude resin glycoside fraction from the leaves and stems of Calystegia japonica7
Azamollugin, a mollugin derivative, has inhibitory activity on MyD88- and TRIF-dependent pathways7
Correction: Ellagic acid prevents ovariectomy-induced bone loss and attenuates oxidative damage of osteoblasts by activating SIRT17
Two new β-carboline alkaloids from the roots of Anemone altaica7
Correction: Inhibition of Aβ aggregation by naphtho-γ-pyrone derivatives from a marine-derived fungus, Aspergillus sp. MPUC2397
Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells7
3-Oxo-11αH-germacra-1(10) E,4Z-dien-12,6α-olide, a sesquiterpene from Artemisia sieversiana, attenuates lipopolysaccharide-induced inflammation via NF-κB/MAPK pathways and oxidative stress via ROS pat7
Cathagines A–D, new bisindole alkaloids from Catharanthus roseus7
Inhibitory effects of reumycin produced by Streptomyces sp. TPMA0082 on virulence factors of Pseudomonas aeruginosa7
Nobiletin alleviates hypoxia-induced pulmonary hypertension by inhibiting calcium-sensing receptor7
Comprehensive profiling of phytochemicals in the fruits of Gardenia jasminoides Ellis and its variety using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass sp7
Inhibition of Aβ aggregation by naphtho-γ-pyrone derivatives from a marine-derived fungus, Aspergillus sp. MPUC2397
Antimalarial ceramicines Q-T from Chisocheton ceramicus6
Screening and identification of reactive metabolic compounds of Cortex Periplocae based on glutathione capture-mass spectrometry6
Hypoglycemic effects of mountain caviar extract and inhibitory mechanism of saponins, including momordin Ic, on glucose absorption6
Unprecedented triterpenes with anti-inflammatory activity from Limax maximus6
Correction to: Leveraging knowledge of Asian herbal medicine and its active compounds as COVID-19 treatment and prevention6
Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients6
Oleanane-type triterpene saponins promote extracellular vesicle secretion of human adipose-derived mesenchymal stem cells6
Methoxyflavone glucosides and caffeoyl phenylethanoid glycoside from Lysionotus pauciflorus: their structures and anti-ferroptosis activity6
New biofunctional effects of oleanane-type triterpene saponins6
Cytoprotective effects of Hangekobokuto against corticosterone-induced cell death in HT22 cells6
Traditional medicine meets modern science: Halofuginone’s role in combating autoimmune diseases6
Effects of Gentiopicroside on activation of NLRP3 inflammasome in acute gouty arthritis mice induced by MSU6
Nacre extract from pearl oyster attenuates amyloid beta-induced memory impairment6
Chemical and pharmaceutical evaluation of roasted Ephedra herba and elucidation of the health hazards caused by white smoke generated during processing6
Mechanisms underlying the dynamic changes in tannins associated with food processing and plant growth6
Angelica dahurica extract and its effective component bergapten alleviated hepatic fibrosis by activating FXR signaling pathway6
Isovincathicine from Catharanthus roseus induces apoptosis in A549 cells6
Four new lignans obtained from the leaves of Schisandra cauliflora and their effect on skeletal muscle cell proliferation6
Recent trends in ginseng research6
Baicalin promotes antiviral IFNs production and alleviates type I IFN-induced neutrophil inflammation6
Natural products that target p53 for cancer therapy6
The protective effects of Ninjin’yoeito against liver steatosis/fibrosis in a non-alcoholic steatohepatitis model mouse5
Correction: Ceramicines U–Z from Chisocheton ceramicus and structure–antimalarial activity relationship study5
Dihydroartemisinin inhibited the Warburg effect through YAP1/SLC2A1 pathway in hepatocellular carcinoma5
Correction: Visualizing the spatial distribution of ustalic acid in the fruiting body of Tricholoma kakishimeji5
Improved quantitative analysis of tenuifolin using hydrolytic continuous-flow system to build prediction models for its content based on near-infrared spectroscopy5
Chemical quality evaluation and characteristics of interspecific hybrid (G. uralensis × G. glabra) C-18 strain as a new Licorice cultivar5
Exploring new natural products by utilizing untapped secondary metabolic pathways in actinomycetes5
Paeoniflorin attenuates cuproptosis and ameliorates left ventricular remodeling after AMI in hypobaric hypoxia environments5
Comparison of Menthae Herba written with the same kanji characters (薄荷) in Japan and China5
Formohyperins G–L, polycyclic prenylated benzoylphloroglucinols from the flowers of Hypericum formosanum5
Sulfoquinovosyl diacylglycerol, a component of Holy Basil Ocimum tenuiflorum, inhibits the activity of the SARS-CoV-2 main protease and viral replication in vitro5
Multi-omics analysis reveals the mechanism of action of Atractylodin against depression5
Inhibition of amyloid β aggregation and BACE1, and protective effect on SH-SY5Y cells, by p-terphenyl compounds from mushroom Thelephora aurantiotincta5
Impallidane skeleton as a novel triterpenoid methyl ether from rhizomes of Imperata cylindrica var. koenigii f. pallida5
Enzymatic formation of a prenyl β-carboline by a fungal indole prenyltransferase5
Polypunctosides E-K: seven new steroidal saponins from Polygonatum punctatum Royle ex Kunth and their nitric oxide production inhibitory activities4
Effects of Ephedra Herb extract on the expression of EGFR-activating mutations and c-Met in non-small-cell lung cancer cell line, H1975, and its combined effects with osimertinib4
Loganin ameliorates left ventricular fibrosis and dysfunction induced by pressure overload via the Sirt1/AKT/TGF-β1 signaling pathway4
Ceramicines U–Z from Chisocheton ceramicus and structure–antimalarial activity relationship study4
Grandifolins A–D: three 6/6/5 abietane diterpenes and an abietane diterpene from Salvia grandifolia4
Conventional and molecular pharmacognostic characters integrated with chemical profiles of five Piper plants in the Thai herbal pharmacopoeia and their admixture/adulteration/substitution situations i4
Revision of NMR assignment for Morin-3-O-glucoside and microbial production of Morin-2’-O-glucoside4
Integerrima A–E, phenylethanoid glycosides from the stem of Callicarpa integerrima4
Search for natural products from actinomycetes of the genus Nocardia4
Three-membered ring formation catalyzed by α-ketoglutarate-dependent nonheme iron enzymes4
Resveratrol as a BCL6 natural inhibitor suppresses germinal center derived Non-Hodgkin lymphoma cells growth4
Dihydroartemisinin abolishes cisplatin-induced nephrotoxicity in vivo4
Biotransformation of ginsenoside Rb1 and Rd to four rare ginsenosides and evaluation of their anti-melanogenic effects4
Drimane sesquiterpenoids from cultures of basidiomycete Ganoderma subresinosum4
Podocarpusflavone alleviated renal fibrosis in obstructive nephropathy by inhibiting Fyn/Stat3 signaling pathway4
Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital4
Publisher Correction: New biofunctional effects of oleanane-type triterpene saponins4
Bajitianwan formula extract ameliorates bone loss induced by iron overload via activating RAGE/PI3K/AKT pathway based on network pharmacology and transcriptomic analysis3
Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica3
Content and distribution of prunasin in Perilla frutescens3
Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway3
Comparison of ephedrine and pseudoephedrine contents in 34 Kampo extracts containing Ephedrae Herba used clinically in Japan3
New nitric oxide production inhibitors from Syzygium bullockii3
Polyphyllin I induces rapid ferroptosis in acute myeloid leukemia through simultaneous targeting PI3K/SREBP-1/SCD1 axis and triggering of lipid peroxidation3
Akebia saponin D attenuates allergic airway inflammation through AMPK activation3
Evodiamine inhibits growth of vemurafenib drug-resistant melanoma via suppressing IRS4/PI3K/AKT signaling pathway3
Correction to: Phytomedicinal therapeutics for male infertility: critical insights and scientific updates3
Control of Fusarium and nematodes by entomopathogenic fungi for organic production of Zingiber officinale3
New abietane-type diterpenoids from roots of Euonymus hamiltonianus and their cytotoxicity in human cancer cell3
The ability of callus tissues induced from three Allium plants to accumulate health-beneficial natural products, S-alk(en)ylcysteine sulfoxides3
Screening of growth inhibitors for epithelial–mesenchymal transition-induced cells by TGF-β from plant-based sources identified the active compound hydroxychavicol from Piper bitle3
Regulation of adipogenesis through retinoid X receptor and/or peroxisome proliferator-activated receptor by designed lignans based on natural products in 3T3–L1 cells3
The discovery of herbal drugs and natural compounds as inhibitors of SARS-CoV-2 infection in vitro3
Bioactivity-boosting strategy based on combination of anti-allergic O-methylated catechin with a Citrus flavanone, hesperetin3
Four new stilbenes and one new flavonoid with potential antibacterial and anti-SARS-CoV-2 activity from Cajanus cajan3
Effect of Maillard reaction on the quality of clarified butter, ghee3
New biflavonoids isolated from Xylia kerrii leaves extract with selective cytotoxicity against MH7A human rheumatoid arthritis synovial fibroblast cells3
Correction to: Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase3
Advanced multidimensional quality evaluation of encapsulated peppermint oil products in various formulas3
Euchronin A–F isolated from the Arnebia euchroma (Royle) Johnst. and their anti-proliferative activities in vitro3
Identification of specialized metabolites from Artocarpus lacucha as potent α-glucosidase and acetylcholinesterase inhibitors: enzyme kinetic, in vitro and in silico study3
Vincazalidine A, a unique bisindole alkaloid from Catharanthus roseus3
Novel compounds isolated from health food products containing beni-koji (red yeast rice) with adverse event reports3
Phytochemical investigation of the fruits of Xanthium strumarium and their cytotoxic activity3
Xanthohumol attenuates TXNIP-mediated renal tubular injury in vitro and in vivo diabetic models3
Relationship between ephedrine alkaloid profile in Ephedra gerardiana and soil characteristics of glacial landforms in southeastern Tibetan Plateau, China3
Potential of siphonaxanthin, a green algal carotenoid, to prevent obesity and related diseases3
Metabolism of coclaurine into the WADA-banned substance higenamine: a doping-relevant analytical evaluation of Kampo extracts3
Cheminformatics modeling of the correlation between Bupleurum Root-formula medicines and Excess and Deficiency pattern in the diagnostic criteria of Sho in Kampo (traditional Japanese medicine) by non3
Saponin constituents of Achyranthes root3
The extract based on the Kampo formula daikenchuto (Da Jian Zhong Tang) induces Bdnf expression and has neurotrophic effects in cultured cortical neurons2
Aplydactylonins A-C, three new sesquiterpenes from the Vietnamese sea hare Aplysia dactylomela and their cytotoxicity2
Correction: Heating or ginger extract reduces the content of Pinellia ternata lectin in the raphides of Pinellia tuber2
Structural analysis of previously unknown natural products using computational methods2
Saikokeishikankyoto extract alleviates muscle atrophy in KKAy mice2
Overwhelming glycyrrhizin production in Glycyrrhiza glabra induced by rihizobial symbiosis2
Phytomedicinal therapeutics for male infertility: critical insights and scientific updates2
Shin’iseihaito (Xinyiqingfeitang) extract ameliorates ovalbumin-induced murine allergic rhinitis by regulating cytokines2
Red ginseng prevents niraparib-induced myelosuppression in C57BL/6 mice via inhibiting p53-mediated upregulation of p21 and p272
Correction to: Solubility enhancement of berberine–baicalin complex by the constituents of Gardenia Fruit2
A new 3,4-seco-isopimarane and three new isopimarane diterpenoids from Kaempferia champasakensis collected from Vietnam and their cytotoxic activities2
Aromatase inhibitors isolated from a flowering tea, snow Chrysanthemum (the capitula of Coreopsis tinctoria Nutt.)2
Total syntheses of surugamides and thioamycolamides toward understanding their biosynthesis2
Byakangelicin alleviates sepsis-associated acute kidney injury by inhibiting inflammation and apoptosis2
Metabolite profiling of Drynariae Rhizoma using 1H NMR and HPLC coupled with multivariate statistical analysis2
Seasonal variation in the total saponin content of platycodon roots cultivated in Japan2
Four new glucosides from the aerial parts of Equisetum sylvaticum2
Proposal for structure revision of pinofuranoxin A through total syntheses of stereoisomers2
Oxomollugin, an oxidized substance in mollugin, inhibited LPS-induced NF-κB activation via the suppressive effects on essential activation factors of TLR4 signaling2
Anti-coronavirus and anti-pulmonary inflammation effects of iridoids, the common component from Chinese herbal medicines for the treatment of COVID-192
Cinnamon bark extract suppresses metastatic dissemination of cancer cells through inhibition of glycolytic metabolism2
Correction to: The ability of callus tissues induced from three Allium plants to accumulate health-beneficial natural products, S-alk(en)ylcysteine sulfoxides2
Anti-inflammatory lindenane sesquiterpenoid dimers from the roots of Chloranthus holostegius var. trichoneurus2
Tenacissoside G reverses paclitaxel resistance by inhibiting Src/PTN/P-gp signaling axis activation in ovarian cancer cells2
Non-enzymatic reactions in biogenesis of fungal natural products2
Comprehensive study on genetic and chemical diversity of Asian medicinal plants, aimed at sustainable use and standardization of traditional crude drugs2
New sesquiterpenes from the soft coral Litophyton arboreum2
New oxepin and dihydrobenzofuran derivatives from Bauhinia saccocalyx roots and their anti-inflammatory, cytotoxic, and antioxidant activities2
Essential oil components in the seed masses of Amomum xanthioides and its related species from Southeast Asia and China2
Insight of action mechanism of Astragaloside IV for relieving of cerebral ischemic injury in a rat model of middle cerebral artery occlusion reperfusion via proteomics and network pharmacology2
Study on the chemical composition and anti-fungi activities of anthraquinones and its glycosides from Rumex japonicus Houtt.2
Refined-JinQi-JiangTang tablet ameliorates hypertension through activation of FGF21/FGFR1 axis in fructose-fed rats2
Hydrophobic constituents of Polygonum multiflorum roots promote renal erythropoietin expression in healthy mice2
Metabolite derived from green tea polyphenol increases and activates plasmacytoid dendritic cells2
Correction to: Evaluation of medicinal plants from Central Kalimantan for antimelanogenesis2
Asiaticoside conveys an antifibrotic effect by inhibiting activation of hepatic stellate cells via the Jagged-1/Notch-1 pathway2
Essential oil composition of Curcuma species and drugs from Asia analyzed by headspace solid-phase microextraction coupled with gas chromatography–mass spectrometry2
Two new ɑ-pyrone derivatives from the endophytic Diaporthe sp. ECN3712
Therapeutic effects of a standardized-flavonoid Diospyros kaki L.f. leaf extract on transient focal cerebral ischemia-induced brain injury in mice2
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