Journal of Natural Medicines

Article	Citations
Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis	53
Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway	32
Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus	28
Shenyan Kangfu tablet alleviates diabetic kidney disease through attenuating inflammation and modulating the gut microbiota	23
Cytotoxic activities of sesquiterpenoids from the aerial parts of Petasites japonicus against cancer stem cells	21
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer via promoting the long noncoding RNA TRHDE-AS1	20
Biosynthesis of medicinally important plant metabolites by unusual type III polyketide synthases	19
A novel challenge of nondestructive analysis on OGATA Koan’s sealed medicine by muonic X-ray analysis	18
The search for, and chemistry and mechanism of, neurotrophic natural products	17
Characteristic metabolites of Hypericum plants: their chemical structures and biological activities	17
Sedative effects of l-menthol, d-camphor, phenylethyl alcohol, and geraniol	17
A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia	16
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway	16
Lateral flow immunoassay for small-molecules detection in phytoproducts: a review	16
Structure and anticancer activity of a new lectin from the cultivated red alga, Kappaphycus striatus	15
Costunolide and dehydrocostuslactone from Saussurea lappa root inhibit autophagy in hepatocellular carcinoma cells	15
Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study	14
Effects of Gentiopicroside on activation of NLRP3 inflammasome in acute gouty arthritis mice induced by MSU	14
Cell death-inducing activities via Hsp inhibition of the sesquiterpenes isolated from Valeriana fauriei	13
Two new bisindole alkaloids from Tabernaemontana macrocarpa Jack	13
Characterization of metabolites in Saposhnikovia divaricata root from Mongolia	13
Isolation and evaluation of trypanocidal activity of sesquiterpenoids, flavonoids, and lignans in Artemisia sieversiana collected in Mongolia	13
Bisindole alkaloids from Voacanga grandifolia leaves	13
Bufadienolides and ecdysteroids from the whole plants of Helleborus niger and their cytotoxicity	13
Limonoids isolated from the Fortunella crassifolia and the Citrus junos with their cell death-inducing activity on Adriamycin-treated cancer cell	13

Phytochemical studies on traditional herbal medicines based on the ethnopharmacological information obtained by field studies	12
Caffeic acid and rosmarinic acid contents in genus Perilla	12
The discovery of herbal drugs and natural compounds as inhibitors of SARS-CoV-2 infection in vitro	12
Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol	12
Three new quassinoids isolated from the wood of Picrasma javanica and their anti-Vpr activities	12
Triterpenoids from Walsura trichostemon	12
Camalexin, an indole phytoalexin, inhibits cell proliferation, migration, and mammosphere formation in breast cancer cells via the aryl hydrocarbon receptor	12
Magnolol upregulates CHRM1 to attenuate Amyloid-β-triggered neuronal injury through regulating the cAMP/PKA/CREB pathway	12
Thiolane-type sulfides from garlic, onion, and Welsh onion	12
4β-Hydroxywithanolide E and withanolide E from Physalis peruviana L. inhibit adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion	11
Five new 2-(2-phenylethyl)chromone derivatives from agarwood	11
PTP1B and α-glucosidase inhibitors from Selaginella rolandi-principis and their glucose uptake stimulation	11
Antiangiogenic effects of AG36, a triterpenoid saponin from Ardisia gigantifolia stapf.	10
Inhibitory effects of cynaropicrin and related sesquiterpene lactones from leaves of artichoke (Cynara scolymus L.) on induction of iNOS in RAW264.7 cells and its high-affinity proteins	10
Epoxyquinophomopsins A and B from endophytic fungus Phomopsis sp. and their activity against tyrosine kinase	10
The acrid raphides in tuberous root of Pinellia ternata have lipophilic character and are specifically denatured by ginger extract	10
Marine natural products that inhibit osteoclastogenesis and promote osteoblast differentiation	10
Indole-3-carboxaldehyde regulates RSV-induced inflammatory response in RAW264.7 cells by moderate inhibition of the TLR7 signaling pathway	10
Analysis of anti-obesity and anti-diabetic effects of acacia bark-derived proanthocyanidins in type 2 diabetes model KKAy mice	9
Metabolic fingerprinting for discrimination of DNA-authenticated Atractylodes plants using 1H NMR spectroscopy	9
Aplydactylonins A-C, three new sesquiterpenes from the Vietnamese sea hare Aplysia dactylomela and their cytotoxicity	9
Resveratrol oligomer structure in Dipterocarpaceaeous plants	9
Chukranoids A–I, isopimarane diterpenoids from Chukrasia velutina	9
UHPLC-MS-based metabolomic approach for the quality evaluation of Pinellia ternata tubers grown in shaded environments	9
Macrocarquinoids A–C, new meroterpenoids from Sargassum macrocarpum	9
Identification of anti-HIV macrocyclic daphnane orthoesters from Wikstroemia ligustrina by LC–MS analysis and phytochemical investigation	9
Comparison of various commercially available cinnamon barks using NMR metabolomics and the quantification of coumarin by quantitative NMR methods	9
EGCG down-regulates MuRF1 expression through 67-kDa laminin receptor and the receptor signaling is amplified by eriodictyol	9
Five matrine-type alkaloids from Sophora tonkinensis	9
Investigations of AGEs’ inhibitory and nephroprotective potential of ursolic acid towards reduction of diabetic complications	8
Identification of herbal components as TRPA1 agonists and TRPM8 antagonists	8
Walsogynes H–O from Walsura chrysogyne	8
Appetite-enhancing effects of inhaling cinnamon, clove, and fennel essential oils containing phenylpropanoid analogues	8
Effects of clovamide and its related compounds on the aggregations of amyloid polypeptides	8
Cliniatines A–C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase	8
Anti-inflammatory canthin-6-one alkaloids from the roots of Thailand Eurycoma longifolia Jack	8
The hepatoprotective efficacy and biological mechanisms of three phenylethanoid glycosides from cistanches herba and their metabolites based on intestinal bacteria and network pharmacology	8
Simultaneous UHPLC/MS quantitative analysis and comparison of Saposhnikoviae radix constituents in cultivated, wild and commercial products	8
Prenylflavonoids from fruit of Macaranga tanarius promote glucose uptake via AMPK activation in L6 myotubes	8
Complanadine F, a novel dimeric alkaloid from Lycopodium complanatum	8
Environmental and soil characteristics in Ephedra habitats of Uzbekistan	8
Licoricidin improves neurological dysfunction after traumatic brain injury in mice via regulating FoxO3/Wnt/β-catenin pathway	8
Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery	8
Leveraging knowledge of Asian herbal medicine and its active compounds as COVID-19 treatment and prevention	8
Diosgenin content is a novel criterion to assess memory enhancement effect of yam extracts	8
One-pot enantioselective synthesis of (S)-spirobrassinin and non-natural (S)-methylspirobrassinin from amino acids using a turnip enzyme	8
Amyloid β aggregation inhibitory activity of triterpene saponins from the cactus Stenocereus pruinosus	8
Oral administration of Jumihaidokuto inhibits UVB-induced skin damage and prostaglandin E2 production in HR-1 hairless mice	8
Physical and chemical characteristics of soils in Ephedra gerardiana and E. pachyclada habitats of Kali Gandaki Valley in Central Nepal	7
Phelligridin D from Inonotus obliquus attenuates oxidative stress and accumulation of ECM in mesangial cells under high glucose via activating Nrf2	7

Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder	7
Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice	7
Diversity in principal constituents of plants with a lemony scent and the predominance of citral	7
Caloforines A–G, coumarins from the bark of Calophyllum scriblitifolium	7
Anti-insulin resistance effect of constituents from Senna siamea on zebrafish model, its molecular docking, and structure–activity relationships	7
Diversity of Adenostemma lavenia, multi-potential herbs, and its kaurenoic acid composition between Japan and Taiwan	7
Quassilactones A and B, structural characterization of a new class of norquassinoids from Brucea javanica	7
Essential oils from Melia azedarach L. (Meliaceae) leaves: chemical variability upon environmental factors	7
Relationship between ephedrine alkaloid profile in Ephedra gerardiana and soil characteristics of glacial landforms in southeastern Tibetan Plateau, China	7
Quality evaluation of Angelicae acutilobae radix: individual differences and localization of (Z)-ligustilide in Angelica acutiloba root	7
Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway	7
Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway	7
Biological activity evaluations of chemical constituents derived from Mongolian medicinal forage plants and their applications in combating infectious diseases and addressing health problems in humans	7
Solubility enhancement of berberine–baicalin complex by the constituents of Gardenia Fruit	6
Triterpenoids from Celastrus orbiculatus Thunb. inhibit RANKL-induced osteoclast formation and bone resorption via c-Fos signaling	6
Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease	6
Trypanocidal and leishmanicidal activity of six limonoids	6
Design and synthesis of analogues of RA-VII—an antitumor bicyclic hexapeptide from Rubiae radix	6
Saponin constituents of Achyranthes root	6
Anti-influenza A virus activity of flavonoids in vitro: a structure–activity relationship	6
Dihydroartemisinin inhibited the Warburg effect through YAP1/SLC2A1 pathway in hepatocellular carcinoma	6
Ent-kaurane-type diterpenoids from Isodonis Herba activate human hair follicle dermal papilla cells proliferation via the Akt/GSK-3β/β-catenin transduction pathway	6
Structural revision of sesbagrandiflorains A and B, and synthesis and biological evaluation of 6-methoxy-2-arylbenzofuran derivatives	6
Four new xanthones and their cytotoxicity from the stems of Garcinia schomburgkiana	6
Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice	6
Phytomedicinal therapeutics for male infertility: critical insights and scientific updates	6
Polypunctosides E-K: seven new steroidal saponins from Polygonatum punctatum Royle ex Kunth and their nitric oxide production inhibitory activities	6
Anthraquinone-containing compound in rhubarb prevents indole production via functional changes in gut microbiota	6
Magnolol inhibits myotube atrophy induced by cancer cachexia through myostatin signaling pathway in vitro	6
Screening for inhibitory effects of crude drugs on furin-like enzymatic activities	6
β-elemene affects angiogenesis of infantile hemangioma by regulating angiotensin-converting enzyme 2 and hypoxia-inducible factor-1 alpha	6
Genomics-directed activation of cryptic natural product pathways deciphers codes for biosynthesis and molecular function	6
Cytotoxicity and growth-inhibiting activity of Astragalus polysaccharides against breast cancer via the regulation of EGFR and ANXA1	6
Changes in the extracted amounts and seasonally variable constituents of Diospyros kaki at different growth stages	5
Cardamonin inhibits the expression of P-glycoprotein and enhances the anti-proliferation of paclitaxel on SKOV3-Taxol cells	5
Antimalarial ceramicines Q-T from Chisocheton ceramicus	5
Indigo enhances wound healing activity of Caco-2 cells via activation of the aryl hydrocarbon receptor	5
Factors affecting 2-(2-phenylethyl)chromones in artificial agarwood	5
Exploration for the real causative agents of licorice-induced pseudoaldosteronism	5
Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3β and Nrf2/NQO1 pathways	5
22-O-(N-Boc-l-glycine) ester of renieramycin M inhibits migratory activity and suppresses epithelial–mesenchymal transition in human lung cancer cells	5
Ellagitannins from Rosa roxburghii suppress poly(I:C)-induced IL-8 production in human keratinocytes	5
Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital	5
Seasonal variation of alkaloids and polyphenol in Ephedra sinica cultivated in Japan and controlling factors	5
Alginic acid inhibits non-small cell lung cancer-induced angiogenesis via activating miR-506 expression	5
Effects of nicotinic acetylcholine receptor-activating alkaloids on anxiety-like behavior in zebrafish	5
Phenylpropanoid conjugated iridoids with anti-malarial activity from the leaves of Morinda morindoides	5
Kamiohnoyneosides A and B, two new polyacetylene glycosides from flowers of edible Chrysanthemum "Kamiohno"	5
Sauchinone: a prospective therapeutic agent-mediated EIF4EBP1 down-regulation suppresses proliferation, invasion and migration of lung adenocarcinoma cells	5
Isolation and evaluation of cardenolides from Lansium domesticum as Notch inhibitors	5
Enzymatic reactions in teleocidin B biosynthesis	5
The phenolic acids from Oplopanax elatus Nakai stems and their potential photo-damage prevention activity	5
Quality evaluation of Pinellia tuber by LC-TOF/MS targeted to ephedrine	5
Pharmacokinetic study of traditional Japanese Kampo medicine shimotsuto used to treat gynecological diseases in rats	5
Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica	5
Drug-interaction between paclitaxel and goshajinkigan extract and its constituents	5
Two new sesquiterpenes from Artemisia annua L.	5
Cinnamon bark extract suppresses metastatic dissemination of cancer cells through inhibition of glycolytic metabolism	5
Cryptadine C, a new C27N3-type Lycopodium alkaloid from Lycopodium cryptomerinum	4
Two new ɑ-pyrone derivatives from the endophytic Diaporthe sp. ECN371	4
Stilbenoids isolated from the roots of Rheum lhasaense under the guidance of the acetylcholinesterase inhibition activity	4
Two new xanthones from the root of Thai Calophyllum inophyllum and their toxicity against colon and liver cancer cells	4
Celastrol attenuates chronic constrictive injury-induced neuropathic pain and inhibits the TLR4/NF-κB signaling pathway in the spinal cord	4
Constituents of Morus alba var. multicaulis leaf improve lipid metabolism by activating the AMPK signaling pathway in HepG2 cells	4
Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase	4
Therapeutic effects of a standardized-flavonoid Diospyros kaki L.f. leaf extract on transient focal cerebral ischemia-induced brain injury in mice	4
Exploration of marine natural resources in Indonesia and development of efficient strategies for the production of microbial halogenated metabolites	4
Anti-trypanosomal screening of Salvadoran flora	4
One-pot discriminant LC/MS quantitative analysis of ephedrine and pseudoephedrine using Finger Masher and their distribution in the aerial stems of Ephedra plants	4
Correction to: Antiinflammatory constituents of Atractylodes chinensis rhizome improve glomerular lesions in immunoglobulin A nephropathy model mice	4
Apigenin exerts chemopreventive effects on lung injury induced by SiO2 nanoparticles through the activation of Nrf2	4
Identifying the compounds that can distinguish between Saposhnikovia root and its substitute, Peucedanum ledebourielloides root, using LC-HR/MS metabolomics	4
In vitro virucidal activity of the theaflavin-concentrated tea extract TY-1 against influenza A virus	4
Is 18α-Glycyrrhizin a real natural product? Improved preparation of 18α-Glycyrrhizin from 18β-Glycyrrhizin as a positive standard for HPLC analysis of licorice extracts	4
Characterization of inter-annual changes in soil microbial flora of Panax ginseng cultivation fields in Shimane Prefecture of Western Japan by DNA metabarcoding using next-generation sequencing	4
Novel insights into the antibacterial activities of cannabinoid biosynthetic intermediate, olivetolic acid, and its alkyl-chain derivatives	4
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose	4
New monoterpenoids from the stigmas of Crocus sativus	4
Hyperdioxanes, dibenzo-1,4-dioxane derivatives from the roots of Hypericum ascyron	4
Two new phenylpropanoids from the resin of Styrax tonkinensis (Pierre) Craib ex Hartw	4

Communiferulins, farnesylated coumarins from the roots of Ferula communis and their anti-neuroinflammatory activity	4
Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms	4
Dibenzocyclooctadiene lignans from Artemisia sieversiana and their anti-inflammatory activities	4
New biofunctional effects of oleanane-type triterpene saponins	4
Brazilian propolis (AF-08) inhibits collagen-induced platelet aggregation without affecting blood coagulation	4
Discovery and investigation of natural Diels–Alderases	4
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters	4
Sedative effects of inhaled Perilla frutescens essential oils on mice	4
Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells	3
Conventional and molecular pharmacognostic characters integrated with chemical profiles of five Piper plants in the Thai herbal pharmacopoeia and their admixture/adulteration/substitution situations i	3
Antiatherosclerotic effects of corilagin via suppression of the LOX-1/MyD88/NF-κB signaling pathway in vivo and in vitro	3
Inhibitory functions of cornuside on TGFBIp-mediated septic responses	3
Biotransformation of ginsenoside Rb1 and Rd to four rare ginsenosides and evaluation of their anti-melanogenic effects	3
Anti-skin-aging effects of tissue-cultured mountain-grown ginseng and quantitative HPLC/ELSD analysis of major ginsenosides	3
Five new resin glycosides, calyhedins XI–XV, from Calystegia hederacea	3
Soshiho-tang protects LPS-induced acute liver injury by attenuating inflammatory response	3
Regulatory science of natural products	3
Cloning of the cytochrome P450 enzyme from Perilla frutescens involved in nothoapiole biosynthesis	3
Application of the highly sensitive labeling reagent to the structural confirmation of readily isomerizable peptides	3
Picrotoxane sesquiterpene and α-pyrone derivative from Dendrobium signatum and their free radical scavenging potency	3
Three-membered ring formation catalyzed by α-ketoglutarate-dependent nonheme iron enzymes	3
Four new pyrrole alkaloids from the rhizomes of Amomum koenigii	3
Hepatoprotective functions of jujuboside B	3
Ursane-type triterpene oligoglycosides with anti-hepatosteatosis and anti-hyperlipidemic activity from the leaves of Ilex paraguariensis A. St.-Hil.	3
Identification of pheophorbide a as an inhibitor of receptor for advanced glycation end products in Mallotus japonicus	3
Anti-metastatic effects of ergosterol peroxide from the entomopathogenic fungus Ophiocordyceps gracilioides on 4T1 breast cancer cells	3
Phenylpropanoid-conjugated iridoid glucosides from leaves of Morinda morindoides	3
Bie Jia Jian pill enhances the amelioration of bone mesenchymal stem cells on hepatocellular carcinoma progression	3
Effect of Maillard reaction on the quality of clarified butter, ghee	3
Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients	3
Anti-Vpr activities of sesqui- and diterpenoids from the roots and rhizomes of Kaempferia candida	3
Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica	3
Comparison of phenolic compounds contained in Aquilaria leaves of different species	3
Inhibitory effect of Bofutsushosan (Fangfengtongshengsan) extract on the absorption of fructose in rats and mice	3
Comprehensive profiling of phytochemicals in the fruits of Gardenia jasminoides Ellis and its variety using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass sp	3
Tryptanthrin ameliorates imiquimod-induced psoriasis in mice by suppressing inflammation and oxidative stress via NF-κB/MAPK/Nrf2 pathways	3
Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction	3
Recent studies on chemical constituents of Ophiorrhiza plants	3
New nitric oxide production inhibitors from Syzygium bullockii	3
Analgesic potency of intrathecally administered punicalagin in rat neuropathic and inflammatory pain models	3
The ability of callus tissues induced from three Allium plants to accumulate health-beneficial natural products, S-alk(en)ylcysteine sulfoxides	3