Journal of Natural Medicines

Article	Citations
Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis	67
Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway	38
Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus	36
Astragaloside IV inhibits cell proliferation and metastasis of breast cancer via promoting the long noncoding RNA TRHDE-AS1	22
Lateral flow immunoassay for small-molecules detection in phytoproducts: a review	20
Characteristic metabolites of Hypericum plants: their chemical structures and biological activities	20
A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia	20
Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway	19
A novel challenge of nondestructive analysis on OGATA Koan’s sealed medicine by muonic X-ray analysis	19
Sedative effects of l-menthol, d-camphor, phenylethyl alcohol, and geraniol	18
Structure and anticancer activity of a new lectin from the cultivated red alga, Kappaphycus striatus	17
Costunolide and dehydrocostuslactone from Saussurea lappa root inhibit autophagy in hepatocellular carcinoma cells	17
Phytochemical studies on traditional herbal medicines based on the ethnopharmacological information obtained by field studies	17
The discovery of herbal drugs and natural compounds as inhibitors of SARS-CoV-2 infection in vitro	16
Effects of Gentiopicroside on activation of NLRP3 inflammasome in acute gouty arthritis mice induced by MSU	15
Camalexin, an indole phytoalexin, inhibits cell proliferation, migration, and mammosphere formation in breast cancer cells via the aryl hydrocarbon receptor	15
Bisindole alkaloids from Voacanga grandifolia leaves	14
Magnolol upregulates CHRM1 to attenuate Amyloid-β-triggered neuronal injury through regulating the cAMP/PKA/CREB pathway	14
Limonoids isolated from the Fortunella crassifolia and the Citrus junos with their cell death-inducing activity on Adriamycin-treated cancer cell	14
Bufadienolides and ecdysteroids from the whole plants of Helleborus niger and their cytotoxicity	14
Cell death-inducing activities via Hsp inhibition of the sesquiterpenes isolated from Valeriana fauriei	13
Thiolane-type sulfides from garlic, onion, and Welsh onion	13
Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery	13
Two new bisindole alkaloids from Tabernaemontana macrocarpa Jack	13
Diversity in principal constituents of plants with a lemony scent and the predominance of citral	12

Inhibitory effects of cynaropicrin and related sesquiterpene lactones from leaves of artichoke (Cynara scolymus L.) on induction of iNOS in RAW264.7 cells and its high-affinity proteins	12
Dihydroartemisinin inhibited the Warburg effect through YAP1/SLC2A1 pathway in hepatocellular carcinoma	12
Triterpenoids from Walsura trichostemon	12
4β-Hydroxywithanolide E and withanolide E from Physalis peruviana L. inhibit adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion	11
Identification of herbal components as TRPA1 agonists and TRPM8 antagonists	11
Simultaneous UHPLC/MS quantitative analysis and comparison of Saposhnikoviae radix constituents in cultivated, wild and commercial products	11
UHPLC-MS-based metabolomic approach for the quality evaluation of Pinellia ternata tubers grown in shaded environments	11
Identification of anti-HIV macrocyclic daphnane orthoesters from Wikstroemia ligustrina by LC–MS analysis and phytochemical investigation	11
Marine natural products that inhibit osteoclastogenesis and promote osteoblast differentiation	11
Comparison of various commercially available cinnamon barks using NMR metabolomics and the quantification of coumarin by quantitative NMR methods	11
Leveraging knowledge of Asian herbal medicine and its active compounds as COVID-19 treatment and prevention	11
Epoxyquinophomopsins A and B from endophytic fungus Phomopsis sp. and their activity against tyrosine kinase	11
Discovery and investigation of natural Diels–Alderases	11
The hepatoprotective efficacy and biological mechanisms of three phenylethanoid glycosides from cistanches herba and their metabolites based on intestinal bacteria and network pharmacology	10
Anti-insulin resistance effect of constituents from Senna siamea on zebrafish model, its molecular docking, and structure–activity relationships	10
Ellagitannins from Rosa roxburghii suppress poly(I:C)-induced IL-8 production in human keratinocytes	10
Analysis of anti-obesity and anti-diabetic effects of acacia bark-derived proanthocyanidins in type 2 diabetes model KKAy mice	10
Metabolic fingerprinting for discrimination of DNA-authenticated Atractylodes plants using 1H NMR spectroscopy	10
Indole-3-carboxaldehyde regulates RSV-induced inflammatory response in RAW264.7 cells by moderate inhibition of the TLR7 signaling pathway	10
Five matrine-type alkaloids from Sophora tonkinensis	10
Prenylflavonoids from fruit of Macaranga tanarius promote glucose uptake via AMPK activation in L6 myotubes	10
Amyloid β aggregation inhibitory activity of triterpene saponins from the cactus Stenocereus pruinosus	10
Anti-influenza A virus activity of flavonoids in vitro: a structure–activity relationship	10
Essential oils from Melia azedarach L. (Meliaceae) leaves: chemical variability upon environmental factors	9
Caloforines A–G, coumarins from the bark of Calophyllum scriblitifolium	9
Complanadine F, a novel dimeric alkaloid from Lycopodium complanatum	9
Phytomedicinal therapeutics for male infertility: critical insights and scientific updates	9
Aplydactylonins A-C, three new sesquiterpenes from the Vietnamese sea hare Aplysia dactylomela and their cytotoxicity	9
One-pot enantioselective synthesis of (S)-spirobrassinin and non-natural (S)-methylspirobrassinin from amino acids using a turnip enzyme	9
Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway	9
Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder	9
Oral administration of Jumihaidokuto inhibits UVB-induced skin damage and prostaglandin E2 production in HR-1 hairless mice	9
Polypunctosides E-K: seven new steroidal saponins from Polygonatum punctatum Royle ex Kunth and their nitric oxide production inhibitory activities	9
Chukranoids A–I, isopimarane diterpenoids from Chukrasia velutina	9
Effects of clovamide and its related compounds on the aggregations of amyloid polypeptides	9
Environmental and soil characteristics in Ephedra habitats of Uzbekistan	9
Investigations of AGEs’ inhibitory and nephroprotective potential of ursolic acid towards reduction of diabetic complications	9
Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease	8
β-elemene affects angiogenesis of infantile hemangioma by regulating angiotensin-converting enzyme 2 and hypoxia-inducible factor-1 alpha	8
Diversity of Adenostemma lavenia, multi-potential herbs, and its kaurenoic acid composition between Japan and Taiwan	8
Relationship between ephedrine alkaloid profile in Ephedra gerardiana and soil characteristics of glacial landforms in southeastern Tibetan Plateau, China	8
Exploration for the real causative agents of licorice-induced pseudoaldosteronism	8
Cliniatines A–C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase	8
Walsogynes H–O from Walsura chrysogyne	8
Phelligridin D from Inonotus obliquus attenuates oxidative stress and accumulation of ECM in mesangial cells under high glucose via activating Nrf2	8
Anthraquinone-containing compound in rhubarb prevents indole production via functional changes in gut microbiota	7
Ent-kaurane-type diterpenoids from Isodonis Herba activate human hair follicle dermal papilla cells proliferation via the Akt/GSK-3β/β-catenin transduction pathway	7
Indigo enhances wound healing activity of Caco-2 cells via activation of the aryl hydrocarbon receptor	7
Pharmacokinetic study of traditional Japanese Kampo medicine shimotsuto used to treat gynecological diseases in rats	7
Saponin constituents of Achyranthes root	7

Biological activity evaluations of chemical constituents derived from Mongolian medicinal forage plants and their applications in combating infectious diseases and addressing health problems in humans	7
New biofunctional effects of oleanane-type triterpene saponins	7
Screening for inhibitory effects of crude drugs on furin-like enzymatic activities	7
Four new xanthones and their cytotoxicity from the stems of Garcinia schomburgkiana	7
Antiatherosclerotic effects of corilagin via suppression of the LOX-1/MyD88/NF-κB signaling pathway in vivo and in vitro	7
Daldinans D‒G, new isoindolinone antioxidants isolated from the ascomycete Daldinia concentrica	7
Anti-metastatic effects of ergosterol peroxide from the entomopathogenic fungus Ophiocordyceps gracilioides on 4T1 breast cancer cells	7
New nitric oxide production inhibitors from Syzygium bullockii	7
Nacre extract from pearl oyster attenuates amyloid beta-induced memory impairment	7
Design and synthesis of analogues of RA-VII—an antitumor bicyclic hexapeptide from Rubiae radix	7
Cytotoxicity and growth-inhibiting activity of Astragalus polysaccharides against breast cancer via the regulation of EGFR and ANXA1	7
Seasonal variation of alkaloids and polyphenol in Ephedra sinica cultivated in Japan and controlling factors	6
Biotransformation of ginsenoside Rb1 and Rd to four rare ginsenosides and evaluation of their anti-melanogenic effects	6
Effects of nicotinic acetylcholine receptor-activating alkaloids on anxiety-like behavior in zebrafish	6
Alginic acid inhibits non-small cell lung cancer-induced angiogenesis via activating miR-506 expression	6
Phenylpropanoid conjugated iridoids with anti-malarial activity from the leaves of Morinda morindoides	6
Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells	6
Hyperdioxanes, dibenzo-1,4-dioxane derivatives from the roots of Hypericum ascyron	6
Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3β and Nrf2/NQO1 pathways	6
Ursane-type triterpene oligoglycosides with anti-hepatosteatosis and anti-hyperlipidemic activity from the leaves of Ilex paraguariensis A. St.-Hil.	6
Cardamonin inhibits the expression of P-glycoprotein and enhances the anti-proliferation of paclitaxel on SKOV3-Taxol cells	6
Recent studies on chemical constituents of Ophiorrhiza plants	6
Constituents of Morus alba var. multicaulis leaf improve lipid metabolism by activating the AMPK signaling pathway in HepG2 cells	6
22-O-(N-Boc-l-glycine) ester of renieramycin M inhibits migratory activity and suppresses epithelial–mesenchymal transition in human lung cancer cells	6
Antimalarial ceramicines Q-T from Chisocheton ceramicus	6
Is 18α-Glycyrrhizin a real natural product? Improved preparation of 18α-Glycyrrhizin from 18β-Glycyrrhizin as a positive standard for HPLC analysis of licorice extracts	6
Exploration of marine natural resources in Indonesia and development of efficient strategies for the production of microbial halogenated metabolites	6
Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice	6
Cryptadine C, a new C27N3-type Lycopodium alkaloid from Lycopodium cryptomerinum	6
Changes in the extracted amounts and seasonally variable constituents of Diospyros kaki at different growth stages	6
Two new xanthones from the root of Thai Calophyllum inophyllum and their toxicity against colon and liver cancer cells	6
Celastrol attenuates chronic constrictive injury-induced neuropathic pain and inhibits the TLR4/NF-κB signaling pathway in the spinal cord	6
Characterization of inter-annual changes in soil microbial flora of Panax ginseng cultivation fields in Shimane Prefecture of Western Japan by DNA metabarcoding using next-generation sequencing	6
Quality evaluation of Pinellia tuber by LC-TOF/MS targeted to ephedrine	6
Baicalin promotes antiviral IFNs production and alleviates type I IFN-induced neutrophil inflammation	6
Aromatase inhibitors isolated from a flowering tea, snow Chrysanthemum (the capitula of Coreopsis tinctoria Nutt.)	6
Genomics-directed activation of cryptic natural product pathways deciphers codes for biosynthesis and molecular function	6
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells	6
Anti-skin-aging effects of tissue-cultured mountain-grown ginseng and quantitative HPLC/ELSD analysis of major ginsenosides	6
Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital	6
Stilbenoids isolated from the roots of Rheum lhasaense under the guidance of the acetylcholinesterase inhibition activity	6
Tryptanthrin ameliorates imiquimod-induced psoriasis in mice by suppressing inflammation and oxidative stress via NF-κB/MAPK/Nrf2 pathways	5
Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction	5
The phenolic acids from Oplopanax elatus Nakai stems and their potential photo-damage prevention activity	5
Four new stilbenes and one new flavonoid with potential antibacterial and anti-SARS-CoV-2 activity from Cajanus cajan	5
Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients	5
New monoterpenoids from the stigmas of Crocus sativus	5
Therapeutic effects of a standardized-flavonoid Diospyros kaki L.f. leaf extract on transient focal cerebral ischemia-induced brain injury in mice	5
Genetic identification of the original plant species for Mentha Herb listed in the Japanese Pharmacopoeia and analyses of their essential oil composition	5
Enzymatic reactions in teleocidin B biosynthesis	5
Five new resin glycosides, calyhedins XI–XV, from Calystegia hederacea	5
In vitro virucidal activity of the theaflavin-concentrated tea extract TY-1 against influenza A virus	5
Cloning of the cytochrome P450 enzyme from Perilla frutescens involved in nothoapiole biosynthesis	5
Novel insights into the antibacterial activities of cannabinoid biosynthetic intermediate, olivetolic acid, and its alkyl-chain derivatives	5
Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica	5
Drug-interaction between paclitaxel and goshajinkigan extract and its constituents	5
Identification of pheophorbide a as an inhibitor of receptor for advanced glycation end products in Mallotus japonicus	5
Inhibitory effect of Bofutsushosan (Fangfengtongshengsan) extract on the absorption of fructose in rats and mice	5
Punicalagin alleviates the hyperproliferation of keratinocytes in psoriasis through inhibiting SKP2 expression	5
Analgesic potency of intrathecally administered punicalagin in rat neuropathic and inflammatory pain models	5
Factors affecting 2-(2-phenylethyl)chromones in artificial agarwood	5
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters	5
Anti-trypanosomal screening of Salvadoran flora	5
Cinnamon bark extract suppresses metastatic dissemination of cancer cells through inhibition of glycolytic metabolism	5
Metabolite profiling of Drynariae Rhizoma using 1H NMR and HPLC coupled with multivariate statistical analysis	4
Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms	4
Inhibitory functions of cornuside on TGFBIp-mediated septic responses	4
Paeoniflorin attenuates cuproptosis and ameliorates left ventricular remodeling after AMI in hypobaric hypoxia environments	4
Dibenzocyclooctadiene lignans from Artemisia sieversiana and their anti-inflammatory activities	4
Bie Jia Jian pill enhances the amelioration of bone mesenchymal stem cells on hepatocellular carcinoma progression	4
Comparison of phenolic compounds contained in Aquilaria leaves of different species	4
Identification and characterization of organic and glycosidic acids in the crude resin glycoside fraction from the leaves and stems of Calystegia japonica	4
One-pot discriminant LC/MS quantitative analysis of ephedrine and pseudoephedrine using Finger Masher and their distribution in the aerial stems of Ephedra plants	4
Essential oil components in the seed masses of Amomum xanthioides and its related species from Southeast Asia and China	4
Communiferulins, farnesylated coumarins from the roots of Ferula communis and their anti-neuroinflammatory activity	4
Four new pyrrole alkaloids from the rhizomes of Amomum koenigii	4
Four new glucosides from the aerial parts of Equisetum sylvaticum	4
Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase	4
Phytochemical investigation of the fruits of Xanthium strumarium and their cytotoxic activity	4
Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose	4

Hepatoprotective functions of jujuboside B	4
Two new ɑ-pyrone derivatives from the endophytic Diaporthe sp. ECN371	4
Metabolomics analysis of peony root using NMR spectroscopy and impact of the preprocessing method for NMR data in multivariate analysis	4
Genetic diversity of Amomum xanthioides and its related species from Southeast Asia and China	4
Apigenin exerts chemopreventive effects on lung injury induced by SiO2 nanoparticles through the activation of Nrf2	4
Conventional and molecular pharmacognostic characters integrated with chemical profiles of five Piper plants in the Thai herbal pharmacopoeia and their admixture/adulteration/substitution situations i	4
Phenylpropanoid-conjugated iridoid glucosides from leaves of Morinda morindoides	4
Recent trends in ginseng research	4
Brazilian propolis (AF-08) inhibits collagen-induced platelet aggregation without affecting blood coagulation	4
Sedative effects of inhaled Perilla frutescens essential oils on mice	4
Comprehensive profiling of phytochemicals in the fruits of Gardenia jasminoides Ellis and its variety using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass sp	4
Optimal harvest-time to maximize the annual camptothecin production by Ophiorrhiza pumila in a plant factory with artificial light	3
Glucosyl-hesperidin enhances the cyclic guanosine monophosphate-inducing effect of a green tea polyphenol EGCG	3
Seasonal variation in the total saponin content of platycodon roots cultivated in Japan	3
Crocetin alleviates the caerulein-induced apoptosis and inflammation in AR42J cells by activating SIRT1 via NF-κB	3
Essential oil composition of Curcuma species and drugs from Asia analyzed by headspace solid-phase microextraction coupled with gas chromatography–mass spectrometry	3
Regulation of adipogenesis through retinoid X receptor and/or peroxisome proliferator-activated receptor by designed lignans based on natural products in 3T3–L1 cells	3
Effect of Maillard reaction on the quality of clarified butter, ghee	3
Application of the highly sensitive labeling reagent to the structural confirmation of readily isomerizable peptides	3
Structure–activity relationship of a housefly neuroprotective dodecapeptide that activates the nuclear factor erythroid 2-related factor 2 pathway	3
Identification of a diarylpentanoid-producing polyketide synthase in the biosynthesis of 2-(2-phenylethyl)chromones in agarwood	3
Picrotoxane sesquiterpene and α-pyrone derivative from Dendrobium signatum and their free radical scavenging potency	3
Anti-Helicobacter pylori activity of swertianolin, isolated from swertia herb	3
Rhein alleviates advanced glycation end products (AGEs)-induced inflammatory injury of diabetic cardiomyopathy in vitro and in vivo models	3
Three-membered ring formation catalyzed by α-ketoglutarate-dependent nonheme iron enzymes	3
A new 1,2-diketone physalin isolated from Physalis minima and TRAIL-resistance overcoming activity of physalins	3
Regulatory science of natural products	3
The ability of callus tissues induced from three Allium plants to accumulate health-beneficial natural products, S-alk(en)ylcysteine sulfoxides	3
Content and distribution of prunasin in Perilla frutescens	3
Correction to: Inhibiting reactive oxygen species-dependent autophagy enhanced baicalein-induced apoptosis in oral squamous cell carcinoma	3
Euchronin A–F isolated from the Arnebia euchroma (Royle) Johnst. and their anti-proliferative activities in vitro	3
Anti-Vpr activities of sesqui- and diterpenoids from the roots and rhizomes of Kaempferia candida	3
Mastic (Pistacia lentiscus) gum and oral health: a state-of-the-art review of the literature	3
Ceramicines U–Z from Chisocheton ceramicus and structure–antimalarial activity relationship study	3
Genetic diversity of Panax ginseng cultivated in Japan and its relation with some plant characteristics	3
Study on morphological and genetic diversity of Rehmannia glutinosa cultivated in Japan	3
Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy	3
Quantification of ustalic acid, a chemotaxonomic marker, in Tricholoma ustale using liquid chromatography–mass spectrometry	3
A feruloylated acylglycerol isolated from Wikstroemia pilosa and its distribution in ten plants of Wikstroemia species	3