OOIR: Observatory of International Research

Papers

(The TQCC of Allergology International is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Assessment of serum periostin level as a predictor of requirement for intensive treatment for type-2 inflammation in asthmatics in future: A follow-up study of the KiHAC cohort	122
Elevated MS4A2 and IgE interaction in nasal polyps contributing to poor postoperative prognosis in patients with eosinophilic chronic rhinosinusitis	90
A systematic review and meta-analysis of macrolides in the management of adult patients with asthma	79
Individual multidisciplinary clinical phenotypes of nasal and ocular symptoms in hay fever: Crowdsourced cross-sectional study using AllerSearch	63
Airway epithelial STAT3 inhibits allergic inflammation via upregulation of stearoyl-CoA desaturase 1	59
Validation of asthma discrimination criteria using health insurance claims data in Japan: Additional proposals for more specific criteria	53
Celecoxib induced respiratory symptoms without urinary LTE 4 increase in a patient with AERD	50
Safety, efficacy, and pharmacokinetics of delgocitinib ointment in infants with atopic dermatitis: A phase 3, open-label, and long-term study	42
Nailfold capillaroscopic abnormalities in angioedema with eosinophilia	37
Small airway dysfunction in asthma based on oscillometry	30
CYP27A1-27-hydroxycholesterol axis in the respiratory system contributes to house dust mite-induced allergic airway inflammation	30
Neurodevelopment at 6 years of age in children with atopic dermatitis	30
Potential determinants of T helper 2 markers and their distribution in school-aged children	29
Periostin is an aggravating factor and predictive biomarker of eosinophilic chronic rhinosinusitis	29
Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma	29
Similarities and differences in autoinflammatory diseases with urticarial rash, cryopyrin-associated periodic syndrome and Schnitzler syndrome	27
Cross-antigen analysis for allergies to multiple legumes (azuki beans, runner beans, white pea beans)	26
Investigator-initiated, multi-center, single-arm, open-label study of the effectiveness of canakinumab in Japanese patients with Schnitzler syndrome	25
Hyper-IgE syndrome, 2021 update	24
Treatments of refractory eosinophilic lung diseases with biologics	22
Sensitization to macadamia 7S globulin amino-terminus with clinical relevance in Japanese children with macadamia nut allergy	21
Blood eosinophil count variability in chronic obstructive pulmonary disease and severe asthma	21
LncRNA FAM239A modulates T helper cell responses via tyrosine phosphatase SHP2 in allergic rhinitis	20
Current perspective on allergen immunotherapy for food allergies	19
Group 2 innate lymphoid cells in human asthma	18

Role of basal cells in nasal polyp epithelium in the pathophysiology of eosinophilic chronic rhinosinusitis (eCRS)	18
Efficacy and safety of dupilumab with concomitant topical corticosteroids in Japanese pediatric patients with moderate-to-severe atopic dermatitis: A randomized, double-blind, placebo-controlled phase	18
Chitin induces steroid-resistant airway inflammation and airway hyperresponsiveness in mice	18
Effects of raw seafood on the risk of hypersensitivity reaction recurrence in patients with an Anisakis allergy: A retrospective observational study in Japan	17
Cytokine profile of the stratum corneum in atopic dermatitis lesions differs between the face and the trunk	17
Efficacy and safety of tezepelumab in patients recruited in Japan who participated in the phase 3 NAVIGATOR study	17
S100A8 enhances IL-1β production from nasal epithelial cells in eosinophilic chronic rhinosinusitis	17
In vitro cross-reactivity between hen's egg and quail's egg in children with hen's egg allergy	16
Age-related differences in olfactory profiles and surgical outcomes in eosinophilic chronic rhinosinusitis	16
Three-year prognoses after low-dose oral food challenge for cow's milk	16
A phase 3, randomized, double-blind, clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough	16
Regulation of the IgE response by T follicular regulatory cells	15
T follicular helper and memory B cells in IgE recall responses	15
T follicular helper cells and IgE	14
Cluster analysis of phenotypes, job exposure, and inflammatory patterns in elderly and nonelderly asthma patients	14
Association of walnut proteins in household dust with household walnut consumption and Jug r 1 sensitization	14
Chronic urticaria and the pathogenic role of mast cells	14
Efficacy of dupilumab for airway hypersecretion and airway wall thickening in patients with moderate-to-severe asthma: A prospective, observational study	13
Safety of local nasal immunotherapy using hypoallergenic birch pollen ointment in patients with pollen-food allergy syndrome: A preliminary study of five cases	13
A 60-minute dosing interval is safer than a 30- or 40-minute interval in oral food challenge	13
Association of Japanese cedar pollen sensitization in children with Dermatophagoides pteronyssinus sensitization and maternal sensitization: Insights from the Yamanashi adjunct study within the Japan	13
Control of immunity and allergy by steroid hormones	13
Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses	12
Nonepisodic angioedema with eosinophilia during sublingual immunotherapy with house dust mite extract	12
Questionnaire survey among ophthalmic allergists on dupilumab-associated ocular surface disease in Japan	12
Exacerbating factors and disease burden in patients with atopic dermatitis	12
Non-IgE-mediated food allergy: Where are we now?	11
Inborn errors of immunity with eosinophilia	11
Biochemistry, molecular genetics, and clinical aspects of hereditary angioedema with and without C1 inhibitor deficiency	10
Rapid progress in molecular targeted therapy for allergic diseases	10
Valuable lessons from analyses of common signs and symptoms in rare diseases	10
Genomic analysis reveals novel allergens of Blomia tropicalis	10
The latest findings on ILC2s, from bench to bedside	10
Eosinophilic mucus diseases	10
Fasting-associated urticaria and/or anaphylaxis: A case report	9
Association between house renovation during pregnancy and wheezing in the first year of life: The Japan environment and children's study	9
Analysis of drug-induced anaphylaxis cases using the Japanese Adverse Drug Event Report (JADER) database – secondary publication	9
Executive summary: Japanese guidelines for allergic rhinitis 2020	9
Reducing the solubility of the major birch pollen allergen Bet v 1 by particle-loading mitigates Th2 responses	9
Antigen analysis of patients with gastrointestinal symptoms resulting from immediate allergic reactions to mushrooms	9
Meropenem allergy testing performed at the bedside of hospitalized patients labelled with a penicillin allergy	9
Sub-pollen in platelet products: A potential cause of allergic transfusion reactions	9
Allergic bronchopulmonary mycosis associated with a novel pathogen: Bjerkandera adusta	9
The clinical features of intractable allergic rhinitis based on a questionnaire administered to clinicians	8
Contribution of monocyte and macrophage extracellular traps to neutrophilic airway inflammation in severe asthma	8
A diagnostic score for eosinophilic granulomatosis with polyangiitis among eosinophilic disorders	8
Analysis of the relationship between comorbid obstructive sleep apnea and clinical outcomes in patients with asthma in Japan	8
Innovation in the treatment of atopic dermatitis: Emerging topical and oral Janus kinase inhibitors	8
Fluctuations of aeroallergen-specific immunoglobulins and children's allergic profiles: Japan Environment & Children's Study of a pilot cohort	8
Insights from the COCOA birth cohort: The origins of childhood allergic diseases and future perspectives	8

A clinical and canine experimental study in small-airway response to bronchial thermoplasty: Role of the neuronal effect	8
Overviewing allergy epidemiology in Japan - Findings from birth cohorts (JECS and T-Child study)	8
Periostin upregulates the effector functions of neutrophils	8
IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice	8
Overweight improves long-term survival in Japanese patients with asthma	7
Advantage of spirometry over oscillometry to detect dupilumab's effect on small airway dysfunction	7
Hydrogen sulfide as a novel biomarker of asthma and chronic obstructive pulmonary disease	7
Effect of gut microbial composition and diversity on major inhaled allergen sensitization and onset of allergic rhinitis	7
Detection of anti-MGL_1304 IgE using the ImmunoCAP system for diagnosis of type I allergy to sweat	7
Real-world safety and effectiveness of omalizumab in Japanese patients with chronic spontaneous urticaria: A post-marketing surveillance study	7
Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans	7
ORMDL3/GSDMB genotype is associated with distinct phenotypes of adult asthma	7
Safe consumption of processed foods after negative medium-dose cow's milk oral food challenge	7
Relationship between Aspergillus and asthma	7
Potential of MAIT cells to modulate asthma	7
Is oral food challenge useful to avoid complete elimination in Japanese patients diagnosed with or suspected of having IgE-dependent hen's egg allergy? A systematic review	7
Serum polyethylene glycol-specific IgE and IgG in patients with hypersensitivity to COVID-19 mRNA vaccines	6
Impact of obesity in asthma: Possible future therapies	6
Associations of fractional exhaled nitric oxide with airway dimension and mucus plugs on ultra-high-resolution computed tomography in former smokers and nonsmokers with asthma	6
Gut microbiota and allergic diseases in children	6
Efficacy of a house dust mite sublingual immunotherapy tablet as add-on dupilumab in asthma with rhinitis	6
Peripheral itch sensitization in atopic dermatitis	6
Mortality and risk factors on admission in toxic epidermal necrolysis: A cohort study of 59 patients	6
Characteristics of food protein-induced enterocolitis syndrome with metabolic acidosis: A case–control study	6
Development and validation of a new asthma questionnaire to help achieve a high level of control in school-age children and adolescents	6
Efficacy of sequential fecal-marker examination for evaluating gastrointestinal inflammation in solid food protein-induced enterocolitis syndrome	6
Effects of subcutaneous allergen immunotherapy on non-targeted allergen-induced immune responses	6
Differential patterns of fish sensitization in Asian populations: Implication for precision diagnosis	6
Alarmins/stressorins and immune dysregulation in intractable skin disorders	6
Poorly controlled asthma – Easy wins and future prospects for addressing fungal allergy	6
Topical application of activator protein-1 inhibitor T-5224 suppresses inflammation and improves skin barrier function in a murine atopic dermatitis-like dermatitis	6
Skin health survey on atopic dermatitis among Japanese children: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study	6
Clinical and histological characterization of transient dermal pain triggered by sweating stimuli	6
Multiplex component-based allergen macroarray test is useful to predict clinical reactivity to tree nuts in children	6