OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology & Biotechnological Equipment is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Plant drought stress tolerance: understanding its physiological, biochemical and molecular mechanisms	79
Common bean as a potential crop for future food security: an overview of past, current and future contributions in genomics, transcriptomics, transgenics and proteomics	50
DNA-free gene editing in plants: a brief overview	33
Antimicrobial activity of chitosan nanoparticles	31
The role of bioactive phytoconstituents-loaded nanoemulsions for skin improvement: a review	26
Functional profiling of bacterial communities in Lake Tuz using 16S rRNA gene sequences	25
Aquaponic systems: biological and technological parameters	25
Characterization of β-mannanase extracted from a novel Streptomyces species Alg-S25 immobilized on chitosan nanoparticles	22
Role of core structural genes for flavonoid biosynthesis and transcriptional factors in flower color of plants	18
Microbial community changes during the mechanized production of light aromaXiaoqu baijiu	18
Research progress in biosynthesis and regulation of plant terpenoids	17
Patterns of genome-wide codon usage bias in tobacco, tomato and potato	17
Organic dyes in contemporary medicinal chemistry and biomedicine. I. From the chromophore to the bioimaging/bioassay agent	17
A brief overview of global biotechnology	15
Transcriptome-based analysis of salt-related genes during the sprout stage of common bean (Phaseolus vulgaris) under salt stress conditions	15
Endophytic Bacillus altitudinis Q7 from Ginkgo biloba inhibits the growth of Alternaria alternata in vitro and its inhibition mode of action	14
Evaluation of an enclosed air-lift photobioreactor (ALPBR) for biomass and lipid biosynthesis of microalgal cells grown under fluid-induced shear stress	14
The virus that shook the world: questions and answers about SARS-CoV-2 and COVID-19	13
Tetracycline removal from model aqueous solutions by pretreated waste Streptomyces fradiae biomass	12
Plant extracts and Trichoderma spp: possibilities for implementation in agriculture as biopesticides	12
Effects of cadmium stress on DNA methylation in soybean	12
Innovative technological advancements in laboratory medicine: Predicting the lab of the future	12
Expression analysis of miRNAs and their targets related to salt stress in Solanum lycopersicum H-2274	11
Recent advances and future prospects in topical creams from medicinal plants to expedite wound healing: a review	11
High sensitivity of roots to salt stress as revealed by novel tip bioassay in wheat seedlings	11

Cytotoxic and antiproliferative effects of the nonsteroidal anti-inflammatory drug diclofenac in human tumour cell lines	10
Exogenous application of melatonin may contribute to enhancement of soybean drought tolerance via its effects on glucose metabolism	10
Genetic diversity and structure of 2 indigenous sheep breeds (Kotel and Teteven) in Bulgaria using microsatellite markers	10
Analysis of regulatory elements in GA2ox, GA3ox and GA20ox gene families in Arabidopsis thaliana: an important trait	10
Identification and quantification of anthocyanins of 62 blueberry cultivars via UPLC-MS	9
Ethanolic extract of Turkish bee pollen and propolis: phenolic composition, antiradical, antiproliferative and antibacterial activities	9
Microbial functional diversity in rhizosphere and non-rhizosphere soil of different dominant species in a vegetation concrete slope	9
Evaluation of genetic variability and relatedness among eight Centaurea species through CAAT-box derived polymorphism (CBDP) and start codon targeted polymorphism (SCoT) markers	9
State of the art and applications in nanostructured biocatalysis	9
Effects of salt stress on sucrose metabolism and growth in Chinese rose (Rosa chinensis)	9
Genome-wide identification and expression analysis of tomato glycoside hydrolase family 1 β-glucosidase genes in response to abiotic stresses	8
Sialic acids, sialoconjugates and enzymes of their metabolism in fungi	8
Time-course RNA-seq analysis provides an improved understanding of genetic regulation in response to cold stress from white clover (Trifolium repens L.)	8
Genomics-guided isolation and identification of active secondary metabolites of Bacillus velezensis BA-26	8
The complete chloroplast genome provides insight into the polymorphism and adaptive evolution of Garcinia paucinervis	8
Identification and expression analysis of capsaicin biosynthesis pathway genes at genome level in Capsicum chinense	8
Effect of acetate metabolism modulation on 2'-fucosyllactose production in engineered Escherichia coli	8
Potential targets for evaluation of sugarcane yellow leaf virus resistance in sugarcane cultivars: in silico sugarcane miRNA and target network prediction	8
Inhibitory activity of carbon quantum dots against Phytophthora infestans and fungal plant pathogens and their effect on dsRNA-induced gene silencing	7
The antitumor activity of cannabidiol on lung cancer cell lines A549 and H1299: the role of apoptosis	7
GE11 peptide modified CSO-SPION micelles for MRI diagnosis of targeted hepatic carcinoma	7
Effect of cadmium on the molecular and morpho-physiological traits ofPisum sativumL.	7
Genetic diversity and population structure of bread wheat varieties grown in Bulgaria based on microsatellite and phenotypic analyses	7
Genome-wide identification of Cellulose-like synthase D gene family in Dendrobium catenatum	7
Analytical detection methods for diagnosis of COVID-19: developed methods and their performance	7
Phytochemical investigation, antioxidant and antibacterial activities of the fruit extracts of Solanum anguivi	7
Comparative study on the metabolic behaviour of anode biofilm in microbial fuel cell under different external resistance	7
Transcriptome analysis of soybean leaves response to manganese toxicity	7
Combinations of mild chemical and bacterial pretreatment for improving enzymatic saccharification of corn stover	7
Effects of exogenous nitric oxide on wild barley (Hordeum brevisubulatum) under salt stress	7
Genome-wide identification of the CCCH gene family in rose (Rosa chinensis Jacq.) reveals its potential functions	7
Investigation on the active ingredient and mechanism of Cannabis sativa L. for treating epilepsy based on network pharmacology	7
Optimization of succinic acid production from xylose mother liquor (XML) by Actinobacillus succinogenes using response surface methodology	7
Decolourization of synthetic dyes by laccase produced from Bacillus sp. NU2	7
Initial sample processing can influence the soil microbial metabarcoding surveys, revealed by Leucocalocybe mongolica fairy ring ecosystem	6
Autologous ovarian platelet rich plasma treatment improves oocyte and embryo quality: a before-after prospective study	6
Effect of exogenous melatonin on salt stress in cucumber: alleviating effect and molecular basis	6
The wheat (Triticum aestiveum L.) MADS-box transcription factor TaMADS32 plays a role in response to abiotic stresses	6
Antibacterial mechanism of Aspergillus niger xj spore powder crude extract B10 against Agrobacterium tumefaciens T-37	6
Generalized anxiety in healthcare workers during the coronavirus pandemic	6
Metabolomics profiling and antimicrobial activity of fermented date fruit (Khastawi) used as functional ingredients for making Asian confectionary (Dodol)	6
Thyroid dysfunction as a long-term post-COVID-19 complication in mild-to-moderate COVID-19	6
Genome-wide identification, phylogeny and expression analysis of the bZIP gene family in Alfalfa (Medicago sativa)	6
Genetic diversity and population structure of modern Bulgarian and foreign durum wheat based on microsatellite and agronomic data	6
Enzyme activities in soils under heavy metal pollution: a case study from the surroundings of a non-ferrous metal plant in Bulgaria	6
Photoprotective activity and HPLC-MS-ESI-IT profile of flavonoids from the barks of Hymenaea martiana Hayne (Fabaceae): development of topical formulations containing the hydroalcoholic extract	6
Protective effect of newly synthesized indole imines against ethanol-induced gastric ulcer in rats	5
Initial safety evaluation of Enterococcus faecium LBB.E81	5
Assaying for antiviral activity of the folkloric medicinal desert plant Rhazya stricta on coronavirus SARS-CoV-2	5
Knockout of the DAS gene increases S-adenosylmethionine production in Komagataella phaffii	5

The antibacterial activity of four Saudi medicinal plants against clinical isolates ofPropionibacterium acnes	5
Efficient biodegradation of nitriles by a novel nitrile hydratase derived from Rhodococcus erythropolis CCM2595	5
Separation of selenium species in plant tissues by high performance liquid chromatography-ultraviolet treatment-hydride generation atomic fluorescence spectrometry using various mobile phases	5
Respiratory viruses crossing the species barrier and emergence of new human coronavirus infectious disease	5
Development of an immunoassay for the detection of human IgG against hepatitis C virus proteins using magnetic beads and flow cytometry	5
DNA barcoding coupled with high resolution melting for rapid identification of Ardisia gigantifolia and its toxic adulterants	5
Fermentation medium optimization, molecular modelling and docking analysis of the alginate lyase of a novel Pseudomonas sp. LB56 isolated from seaweed waste	5
What is the lowest lethal dose of colchicine?	5
Association of paraoxonase (PON1) polymorphisms and activity with colorectal cancer predisposition	5
A polyphasic approach to the characterization of potential silver-nanoparticles–producing and non-producing isolates of Alternaria species and antifungal activity against mycotoxigenic fungi	5
Phytochemical screening, antioxidant and in vitro anticancer activities of Bombax buonopozense stem bark extracts	5
What food will we be eating on our journey to Mars?	5
Microbial profiling identifies potential key drivers in gastric cancer patients	5
Transcriptome analysis reveals light-induced anthocyanin synthesis candidate genes in rabbiteye blueberry (Vaccinium ashei: Reade)	5
Knowledge and attitude toward COVID-19 vaccines amongst medical, dental and pharmacy students. A cross-sectional study from Bulgaria	5
Research on prediction of contact stress of acetabular lining based on principal component analysis and support vector regression	5
Investigation of soil microbiota reveals variable dominant species at different land areas in China	5
Detection of chicken adulteration in beef via ladder-shape melting temperature isothermal amplification (LMTIA) assay	5
Antiviral activity of Humulus lupulus (HOP) aqueous extract against MERS-CoV and SARS-CoV-2: in-vitro and in-silico study	5
The concept for the antivirulence therapeutics approach as alternative to antibiotics: hope or still a fiction?	5
Analysis on bacterial community structure of new and old fermented pit mud of Shedian Liquor	5
Investigation of protein expression of Saccharomyces cerevisiae cells in quiescent and proliferating state before and after toxic stress	5
Identification and characterization of miRNAs and target genes in developing flax seeds by multigroup analysis	4
Ultrasound-assisted lipase-catalyzed synthesis of ethyl acetate: process optimization and kinetic study	4
Hyperglycemia attenuates fibroblast contractility via suppression of TβRII receptor modulated α-smooth muscle actin expression	4
Anti-cancer effect of Petasites hybridus L. (Butterbur) root extract on breast cancer cell lines	4
Ecballium elaterium extract reduces fibrosis during wound healing in rats	4
The common bean (Phaseolus vulgaris) SULTR gene family: genome-wide identification, phylogeny, evolutionary expansion and expression patterns	4
Genome-wide identification and expression pattern of alkaline/neutral invertase gene family inDendrobium catenatum	4
Quercetin affects membrane lipids and apoptosis in three-dimensional fibroblast cultures	4
Integration of transcriptomics and metabolomics to identify key coumarin biosynthetic genes in Bupleurum chinense	4
Astragalus glycyphyllos L.: antiviral activity and tablet dosage formulation of a standardized dry extract	4
Genetic diversity and population structure analysis – a prerequisite for constructing a mini core collection of Balkan Capsicum annuum germplasm	4
Comparative analysis of RNA-Seq data reveals adventitious root development is mediated by ChIFNα in lotus japonicus	4
High-throughput sequencing technology reveals polysaccharides from Angelica dahurica that affect gut microbiota in mice	4
Menadione and hydrogen peroxide trigger specific alterations in RNA polymerases profiles in quiescent Saccharomyces cerevisiae cells	4
The prospect of antimicrobial peptides from Bacillus species with biological control potential against insect pests and diseases of economic importance in agriculture, f	4
Identification and estimation of sequence variation dynamics of Tomato Leaf curl Palampur virus and betasatellite complex infecting a new weed host	4
Defense-related genes induced by application of silver nanoparticles, ascorbic acid and salicylic acid for enhancing the immune response system of eggplant against invasion of root–knot nematode, M	4
Genetic identification of a major, novel and stably expressed QTL for effective tiller number from tetraploid wheat	4
Identification of bioactive compounds in leaves and fruits of Actinidia arguta accessions from northeastern China and assessment of their antioxidant activity with a radical-scavenging effect	4
Molecular characterisation of the oldest domesticated Turkish einkorn wheat landraces with simple sequence repeat (SSR) markers	4
Screening of enzyme-producing strains from traditional Guizhou condiment	4
A survey of knowledge, attitudes and use of antibiotics among Bulgarian population	4
Genome sequence of Bacillus velezensis LZN01 inhibiting Fusarium oxysporum f. sp. niveum and producing myri	4
Prediction of fluid responsiveness: a review	4
Intratumoural expression of IL-6/STAT3, IL-17 and FOXP3 immune cells in the immunosuppressive tumour microenvironment of colorectal cancerImmune cells-positive for IL-6, STAT3, IL-17 and FOXP3 and	4
Enhancing precision medicine through clinical mass spectrometry platform	4
Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study	4
Complete chloroplast genomes of wild and cultivated Cryptomeria japonica var. sinensis	4
Bulked QTL-Seq identified a major QTL for the awnless trait in spring wheat cultivars in Qinghai, China	4
Observation of Spirulina platensis cultivation in a prototype household bubble column photobioreactor during 107 days	4
Bioactivities of crude polysaccharide extracted from fermented soybean curd residue by Cordyceps militaris	4
Nanobodies: their potential for applications in biotechnology, diagnosis and antiviral properties in Africa; focus on application in agriculture	4
Study on patients with Clostridioides difficile infection during the COVID-19 pandemic in Bulgaria	4