OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology & Biotechnological Equipment is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
STING-associated vasculopathy with onset in infancy: the first case in Bulgaria and review of the literature	55
Implementation of DPYD testing in Bulgarian patients with cancer	34
GPC3 as a potential diagnostic and prognostic marker for lung adenocarcinoma	32
The rhizosphere of the pioneer plant Dicranopteris dichotoma (Thunb.) Bernh. contains powerful and robust rhizosphere growth-promoting bacteria	30
High cross-pollination rate of Greek oregano ( O. vulgare ssp. hirtum ) with Common oregano ( O. vulgare ss	27
Endodontic and surgical treatment of chronic apical periodontitis: a randomized clinical study	26
An algorithm and application to efficiently analyse DNA fibre data	25
Identification and estimation of sequence variation dynamics of Tomato Leaf curl Palampur virus and betasatellite complex infecting a new weed host	22
Experimental temperature evaluation during a robotized bone drilling process	16
A comparison of dropout rate of three commonly used single cell RNA-sequencing protocols	15
Leber’s hereditary optic neuropathy: clinical and genetic analysis of Bulgarian patients	15
Costs of treating type 2 diabetes mellitus and its complications	15
Analysis of contrast sensitivity in patients implanted with Acunex Vario and LuxSmart extended depth of focus (E-DOF) intraocular lenses (IOLs)	15
Review and a case of rare Rosai-Dorfman disease	15
Overexpression of MYB transcription factor LrAN2 from Lycium ruthenicum activated the anthocyanin biosynthesis in the leaf and fruit of	14
Development and application of HPV31-specific monoclonal antibodies	13
Diagnostic value of hybrid perfusion SPECT/CT and CTPA for detection of pulmonary embolism	12
Time-course RNA-seq analysis provides an improved understanding of genetic regulation in response to cold stress from white clover (Trifolium repens L.)	12
SARS-CoV-2 variants and genomic surveillance in the low-resource north-west region of Pakistan	12
Mechanism of hydraulic shear generation in activated sludge reactors, its impact on sludge cultivation, and the evolution of quantitative expression methods	11
YKL-40 and LAMPs as possible markers in neuroinflammation and autophagy during central nervous system infections	11
AcdS gene of Bacillus cereus enhances salt tolerance of seedlings in tobacco (Nicotiana tabacum L.)	11
Mining public genomic databases for novel lanthipeptides: a case study on Bacillus amyloliquefaciens	11
3.5 GHz radiofrequency radiation may affect biomechanics of bone and muscle of diabetics	10
West Nile virus meningoencephalitis and cytokines analysis: review and case report	10

Refractive results after cataract surgery in patients: calculation with Holladay II and Barrett Universal II formulas	10
Study on patients with Clostridioides difficile infection during the COVID-19 pandemic in Bulgaria	10
Genome-wide analysis of the GRAS gene family in white clover ( Trifolium repens L.) provides insight into its critical role in response to cold stress	10
A novel prediction method for protein DNA-binding residues based on neighboring residue correlations	10
Inhibitory effect of pentoxifylline on the synthesis and deposition of glycosaminoglycans in hypothyroid skin	9
Combinations of mild chemical and bacterial pretreatment for improving enzymatic saccharification of corn stover	8
Improvement of the antibacterial and skin-protective performance of alcohol-based sanitizers using hydroglycolic phytocompounds	8
Antiviral activity of Humulus lupulus (HOP) aqueous extract against MERS-CoV and SARS-CoV-2: in-vitro and in-silico study	8
Cost/effectiveness of elivaldogene autotemcel vs. hematopoietic stem cells transplantation in patients with cerebral adrenoleukodystrophy (CALD)	8
The common bean (Phaseolus vulgaris) SULTR gene family: genome-wide identification, phylogeny, evolutionary expansion and expression patterns	7
Promoting effect of biogenic AgNPs on Echinops macrochaetus for improving growth parameters and mitigating the toxic effect caused by salinity stress	7
Cytokines levels in saliva in periodontitis, oral potentially malignant disorders and squamous cell carcinoma	7
Whole genome sequencing and functional analysis of porcine-borne Bacillus coagulans LYBC06	7
COVID-19 vaccination and potential predictors for vaccination among students in Bulgarian medical universities	7
Development and validation of a functional molecular marker for a CaAPRR2-like gene that controls green fruit colour in pepper	7
Research and pilot analysis of bevacizumab repurposing potential and its impact in clinical practice	7
Polymorphism in SNP G1 of the GDF9 gene associated with reproductive traits in Bulgarian dairy sheep	6
Analyzing real-world data to understand COVID-19 vaccination effects on hospitalization rates in patients with solid malignancies	6
Synthesis, antiproliferative and antimicrobial activities of (KLAKLAK) ₂ -NH ₂ analogue containing nor-Leu and its conjugates with	6
Research advance and clinical implication of circZNF609 in human diseases	6
The concept for the antivirulence therapeutics approach as alternative to antibiotics: hope or still a fiction?	6
Production and biochemical characterization of keratinase enzyme from Bacillus subtilis ES5 and its potential application in leather dehairing process: a clean leather t	6
Cost-effectiveness of therapeutic drug monitoring (TDM) of biologic treatment in rheumatic diseases: a narrative review	6
Nanodiamonds improve amaranth biodegradation in a lab-scale biofilter	6
Metabolic profiling of probiotic strain Lactobacillus delbrueckii subsp. bulgaricus L14 cultivated in presence of prebiotic oligosaccharid	6
Optimization of intracellular L-Asparaginase production by Streptomyces paulus CA01 isolated from wheat bran using the response surface methodology	6
Surveillance over cytomegalovirus (CMV) reactivation following hematopoietic stem cell transplantation: a single-center experience	5
Deep learning in oral surgery for third molar extraction: empirical evidence and original model	5
35 blood and urine biomarkers in Polycystic Kidney Disease: a bidirectional Mendelian randomization study	5
Investigation of IDO1 and TDO2 expression in breast tumors by immunohistochemistry and real-time polymerase chain reaction methods	5
Association between angiotensinogen M235T gene polymorphism and risk of ischemic stroke among the Ethiopian population: a case control study	5
Chemical composition, antimicrobial and anticancer activities of Paederia lanuginosa WALL	5
Micropropagation of guava ( Psidium guajava ) seedlings, a plant with interest in cool subtropics, using an innovative BB culture medium	5
Analysis of cytokinin content and associated genes at different developmental stages in pak choi (Brassica rapa ssp. chinensis Makino)	5
SRAP markers for characterization of the genetic diversity and differentiation of Pinus nigra populations in protected forested areas in Bulgaria, Greece, and Cyprus	5
Role of pharmacists in adherence in oncology patients	5
Inhibiting immune escape in lung adenocarcinoma: the role of SPARC in suppressing CD276 function	5