Microbes and Infection

Article	Citations
Immunization with the amino-terminus region of dense granule protein 6 (GRA6) of Toxoplasma gondii activates CD8+ cytotoxic T cells capable of removing tissue cysts of the parasite through antigen pre	69
Copyright page Elsevier	50
Borrelia burgdorferi colonizes the mammary glands of lactating C3H mice: does not cause congenital Lyme disease	40
Special issue: emerging technologies for infectious disease research	38
Intense P.1 (Gamma) diversification followed by rapid Delta substitution in Southern Brazil: a SARS-CoV-2 genomic epidemiology study	37
Investigating immune responses of the house cricket, Acheta domesticus to pathogenic Escherichia coli K1	31
SARS-CoV-2 prevalence in wildlife 2020–2022: a worldwide systematic review and meta-analysis	25
Altered cellular immune response to vaccination against SARS-CoV-2 in patients suffering from autoimmunity with B-cell depleting therapy	24
Molecular characterization of the Gyrovirus galga 1 strain detected in various zoo animals: the first report from China	24
Middle East respiratory coronavirus (MERS-CoV) internalized by llama alveolar macrophages does not result in virus replication or induction of pro-inflammatory cytokines	23
Identification of SARS-CoV-2 m6A modification sites correlate with viral pathogenicity	23
The functions of EF-hand proteins from host and zoonotic pathogens	22
Characterization of a rare clinical isolate of A. spinulosporus following a central nervous system infection	22
Conference report: the first bacterial genome sequencing pan-European network conference	22
Helicobacter pylori promotes gastric fibroblast proliferation and migration by expulsing exosomal miR-124-3p	21
Editorial board	20
Upward trend for “Microbes and Infection”	20
Protective efficacy of mucosal and subcutaneous immunization with DnaJ-ΔA146Ply against influenza and Streptococcus pneumoniae co-infection in mice	20
Loss of cilia in chemosensory neurons inhibits pathogen avoidance in Caenorhabditis elegans	19
Chlamydia pneumoniae relies on host glutathione for its growth and induces integrated stress response-mediated changes in macrophage glutathione metabolism	19
Rab27a via its effector JFC1 localizes to Anaplasma inclusions and promotes Anaplasma proliferation in leukocytes	18
Biogenic silver nanoparticles reduce Toxoplasma gondii infection and proliferation in RAW 264.7 macrophages by inducing tumor necrosis factor-alpha and reactive oxygen species production in the cells	18
A systematical association analysis of 25 common virus infection and genetic susceptibility of COVID-19 infection	18
Cutibacterium acnes as an overseen autoimmunity trigger: Unearthing heat-shock driven molecular mimicry	17
Intranasal immunization with poly I:C and CpG ODN adjuvants enhances the protective efficacy against Helicobacter pylori infection in mice	17

Promotion of intestinal epithelial cell apoptosis by enterotoxigenic Escherichia coli via PKA-mediated inhibition of mTORC1 activation	17
Copyright page Elsevier	17
Subcellular particles for characterization of host-parasite interactions	16
Candida albicans causes brain regional invasion and necrosis, and activation of microglia during lethal neonatal neurocandidiasis	16
Engineering Mycoplasma pneumoniae to bypass the association with Guillain-Barré syndrome	16
Acinetobacter baumannii pneumonia increases surfactant proteins SP-A, SP-B, and SP-D levels, while decreasing SP-C level in bronchoalveolar lavage in rats	15
Macrophage-depleted young mice are beneficial in vivo models to assess the translocation of Klebsiella pneumonia from the gastrointestinal tract to the liver in the elderly	15
Extracellular vesicles in the pathogenesis of Campylobacter jejuni	14
Trypanosoma cruzi Vps34 colocalizes with Beclin1 and plays a role in parasite invasion of the host cell by modulating the expression of a sub-group of trans-sialidases	13
Corrigendum to “N-acetyl-cysteine mediates protection against Mycobacterium avium through induction of human β-defensin-2” [Microb Infect 22 (10) (2020) 567–575]	13
The influenza A virus promotes fungal growth of Aspergillus fumigatus via direct interaction in vitro	12
Clinical and genomic data of sars-cov-2 detected in maternal–fetal interface during the first wave of infection in Brazil	12
SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages	12
The SARS-CoV-2 antibody-dependent enhancement façade	11
Editorial board	11
Organoids and organ-on-chip technology for investigating host-microorganism interactions	11
Pro-inflammatory properties of aureocin A53	11
Genomic and phylogenetic profiling of RNA of tick-borne arboviruses in Hainan Island, China	11
Alteration of microbiota and immune response of mice gavaged with Klebsiella oxytoca	10
Dirty mice join the immunologist's toolkit	10
The dual M protein systems have diverse biological characteristics, but both contribute to M18-type Group A Streptococcus pathogenicity	10
Extracellular vesicles secreted by Echinococcus multilocularis: important players in angiogenesis promotion	10
Impacts of clofazimine on the treatment outcomes of drug-resistant tuberculosis	10
A retrospective analysis of Q fever osteomyelitis in children, with recommendations	10
Donor screening for fecal microbiota transplantation with a direct stool testing-based strategy: a prospective cohort study	10
Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection	10
Corydalis saxicola Bunting total alkaloid eliminates Porphyromonas gingivalis strain 33277 internalized into macrophages by inhibition of TLR2	9
Glycolytic stress deteriorates 229E virulence to improve host defense response	9
First report and whole-genome sequencing of Pseudochrobactrum saccharolyticum in Latin America	9
Label-free quantitative proteomics reveals the Steap3-Gm2a axis inhibiting the phagosomal escape of Listeria monocytogenes	9
Time dependent decline of neutralizing antibody titers in COVID-19 patients from Pune, India and evidence of reinfection	9
Integrated analysis of microbiome and host transcriptome unveils correlations between lung microbiota and host immunity in bronchoalveolar lavage fluid of pneumocystis pneumonia patients	9
High-resolution kinetics and cellular determinants of SARS-CoV-2 antibody response over two years after COVID-19 vaccination	9
Identification of two-component system ArcAB and the universal stress protein E in Pasteurella multocida and their effects on bacterial fitness and pathogenesis	8
Real-time, label-free detection and identification of bacteria through non-invasive optical imaging	8
Reduced vitamin D receptor (VDR) and cathelicidin antimicrobial peptide (CAMP) gene expression contribute to the maintenance of inflammatory immune response in leprosy patients	8
Cross-species transmission and animal infection model of hepatitis E virus	8
Metabolic profile and disordered glycerophospholipid metabolism in recurrent vulvovaginal candidiasis	8
LPS-LBP complex induced endothelial cell pyroptosis in aortic dissection is associated with gut dysbiosis	8
Phosphodiesterase delta governs the mechanical properties of erythrocytes infected with Plasmodium falciparum gametocytes	8
HERV-W ENV transcription in B cells predicting symptomatic COVID-19 and risk for long COVID can express a full-length protein despite stop codon in mRNA from chromosome X via a ribosome readthrough	8
Biomolecular condensates with liquid properties formed during viral infections	8
Phylogenetic analysis of Mycobacterium caprae highlights past and present epidemiological links at the Iberian Peninsula scale	8
Beta-lactam induced morphological changes in serum of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae blood isolates	8
Identification of combinatorial mutations associated with colistin resistance in Shewanella algae	8
Chlamydia trachomatis relies on the scavenger role of aryl hydrocarbon receptor with detyrosinated tubulin for its intracellular growth, but this is impaired by excess indole	7
COVID-19 patients with high TNF/IFN-γ levels show hallmarks of PANoptosis, an inflammatory cell death	7
Secondary prophylaxis for Clostridioides difficile infection for patients on non-C. difficile antibiotics: a retrospective cohort study	7
SNP-based high-resolution typing of Chlamydia psittaci from humans and wild birds in Sweden: circulation of the Mat116 genotype reveals the transmission mode to humans	7
Improving the identification and diagnostic efficiency of Metagenomic Next-Generation Sequencing for mycobacterial granuloma on postoperative formalin-fixed paraffin-embedded specimens	7

Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages	7
Controlling viral inflammatory lesions by inhibiting fatty acid metabolism	7
The gut microbiota composition has no predictive value for the endotoxin-induced immune response or development of endotoxin tolerance in humans in vivo	7
Host–parasite interactions after in vitro infection of human macrophages by Leishmania major : Dual analysis of microRNA and mRNA profiles reveals regulation of key processes through time kinetics	7
Role of vaginal microbiota in idiopathic infertility: a prospective study	7
Genomic description and characterization of Nigeribacterium massiliense gen. nov., sp. nov., isolated from the human gut	7
Characterization of Acinetobacter baumannii at a tertiary hospital in Guangzhou: a genomic and clinical study	6
COVID-19 and Fungal infections: a double debacle	6
The “proletarian disease” on stage. Theatrical anti-tuberculosis propaganda in the early Soviet Union	6
Therapeutic approaches for combating Pseudomonas aeruginosa infections	6
Comparative analysis of rabies pathogenic and vaccine strains detection by RIG-I-like receptors	6
MicroRNA-155 triggers a cellular antiviral immune response against Chandipura virus in human microglial cells	6
TRIM32 positively regulates c-di-GMP-Induced type I interferon signaling pathway in Listeria monocytogenes infection	6
Characterization of novel HIV fusion-inhibitory lipopeptides with the M-T hook structure	6
Deficiency in indoleamine-2, 3-dioxygenase induces upregulation of guanylate binding protein 1 and inducible nitric oxide synthase expression in the brain during cerebral infection with Toxoplasma gon	6
Helicobacter pylori acquisition rates and the associated risk factors amongst newlywed couples; a prospective cohort study in Tehran, Iran	6
Editorial board	6
HSP-27 and HSP-70 negatively regulate protective defence responses from macrophages during mycobacterial infection	6
Propionibacterium acnes contributes to low back pain via upregulation of NGF in TLR2-NF-κB/JNK or ROS pathway	6
Uncovering the morphological differences between SARS-CoV-2 and SARS-CoV based on transmission electron microscopy images	6
Transcriptome profiles of macrophages upon infection by morphotypic smooth and rough variants of Mycobacterium abscessus	5
Vitamin D3 affects the gut microbiota in an LPS-stimulated systemic inflammation mouse model	5
Developing and validating a modified enzyme linked immunosorbent assay method for detecting HEV IgG antibody from dried blood spot (DBS) samples in endemic settings	5
Ivermectin-induced bacterial gut dysbiosis does not increase susceptibility to Pseudomonas aeruginosa lung infection but exacerbates liver damage	5
Characterization of Brucella abortus S19 as a challenge strain for use in a mouse model of brucellosis	5
Anti-malarial humoral immunity: the long and short of it	5
Delineating the functional role of the PPE50 (Rv3135) - PPE51 (Rv3136) gene cluster in the pathophysiology of Mycobacterium tuberculosis	5
Cause or effect? The spatial organization of pathogens and the gut microbiota in disease	5
Porphyromonas gingivalis as a promotor in the development of the alcoholic liver disease via ferroptosis	5
The role of sexual dimorphism in susceptibility to SARS-CoV-2 infection, disease severity, and mortality: facts, controversies and future perspectives	5
Characterization and proteome profiling of extracellular vesicles in a murine model of Staphylococcus aureus endophthalmitis	5
Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model	5
Extracellular vesicles in parasitic diseases – from pathogenesis to future diagnostic tools	5
TGEV nonstructural protein ORF3b upregulates the expression of SLA-DR at the transcriptional level in monocyte-derived porcine dendritic cells	5
Editorial board	5
Abnormal M1 polarization of placental macrophage induced by IL-15/STAT5 activation in VVC may lead to adverse pregnancy outcomes	5
Bioactives from medicinal herb against bedaquiline resistant tuberculosis: removing the dark clouds from the horizon	5
Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?	5
Epigenetic reprogramming mechanisms of immunity during influenza A virus infection	5
Elemental sulfur enhances the anti-fungal effect of Lacticaseibacillus rhamnosus Lcr35	5
CD4, but not Cxcr6, is necessary for control of Pneumocystis murina infection	5
Enteroaggregative Escherichia coli induced activation of epidermal growth factor receptor contributes to IL-8 secretion by cultured human intestinal epithelial cells	5
Machine learning-based investigation of the relationship between gut microbiome and obesity status	5
Editorial board	5
Antigenic diversity of MASP gene family of Trypanosoma cruzi	5
Crystal violet decolorization assay: a simplified colorimetric test for the rapid detection of multidrug-resistant Mycobacterium tuberculosis isolates	5
CD38 deficiency up-regulated IL-1β and MCP-1 through TLR4/ERK/NF-κB pathway in sepsis pulmonary injury	5
SARS-CoV-2 neutralizing antibody response in vaccinated and non-vaccinated hospital healthcare workers with or without history of infection	4
Editorial board	4
S100A12 inhibits Streptococcus pneumoniae and aids in wound healing of corneal epithelial cells both in vitro and in vivo	4
Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice	4
Genomic characterization of Listeria spp. isolated from tonsils, udder and feces of domestic dairy ruminants in Spain	4
Potential genes associated with survival of Acinetobacter baumannii under ciprofloxacin stress	4
Host-pathogen interactions from a metabolic perspective: methods of investigation	4
Regulatory T cells in acute and chronic human Chikungunya infection	4
Genotype 4 hepatitis E virus infection and acute pancreatitis	4
A metagenomic study of the gut microbiome in PTB’S disease	4
Combination of colistin and tobramycin inhibits persistence of Acinetobacter baumannii by membrane hyperpolarization and down-regulation of efflux pumps	4
TLR9 promotes monocytic myeloid-derived suppressor cell induction during JEV infection	4
AroC, a chorismate synthase, is required for the formation of Edwardsiella tarda biofilms	4
Human gut microbiota from hepatitis B virus-infected individuals is associated with reduced triglyceride level in mice: faecal transplantation study	4
Imbalance of helper T cell subtypes and adipokine secretion in perivascular adipose tissue as a trigger of atherosclerosis in chronic Porphyromonas gingivalis W83 infection	4
Combination of baloxavir and oseltamivir for treatment of severe influenza infection in hematopoietic cell transplant recipients: a novel treatment strategy for a high-risk population	4
The prebiotic effect of human milk oligosaccharides 3′- and 6′-sialyllactose on adhesion and biofilm formation by Clostridioides difficile – pilot study	4
Phytomelatonin: a potential phytotherapeutic intervention on COVID-19-exposed individuals	4
Infection by exosome-carried Coxsackievirus B3 induces immune escape resulting in an aggravated pathogenesis	4
Airborne infection with Covid-19? A historical look at a current controversy	4
Avian sarcoma/leukosis virus (RCAS)-mediated over-expression of IFITM3 protects chicks from highly pathogenic avian influenza virus subtype H5N1	4
Complement killing of clinical Klebsiella pneumoniae isolates is serum concentration dependent	4
Cross-reactivity and immunotherapeutic potential of BamA recombinant protein from Acinetobacter baumannii	4
MicroRNAs correlate with bacillary index and genes associated to cell death processes in leprosy	4
Hemozoin-induced IFN-γ production mediates innate immune protection against sporozoite infection	4
Talaromyces stipitatus, a novel agent causing superficial mycosis in a diabetic patient from North India	4
Transcriptional regulation of suppressors of cytokine signaling during infection with Mycobacterium tuberculosis in human THP-1-derived macrophages and in mice	4
Gut microb-aging and its relevance to frailty aging	4
Pretreatment of outer membrane vesicle and subsequent infection with influenza virus induces a long-lasting adaptive immune response against broad subtypes of influenza virus	3
Editorial board	3
Prevotella, a dominant bacterium in young people with stage Ⅲ periodontitis, related to the arachidonic acid metabolism pathway	3
NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity	3
Endogenous retroelement expression in modeled airway epithelial repair	3

Intranasal immunization with chitosan microparticles enhances LACK-DNA vaccine protection and induces specific long-lasting immunity against visceral leishmaniasis	3
The great ESKAPE	3
The intestinal microbiota: from health to disease, and back	3
The pathogenic and colonization potential of Candida africana	3
Copyright page Elsevier	3
Editorial board	3
In vivo assessment of differences in fungal cell density in cerebral cryptococcomas of mice infected with Cryptococcus neoformans or Cryptococcus gattii	3
Salmonella-mediated oral delivery of multiple-target vaccine constructs with conserved and variable regions of SARS-CoV-2 protect against the Delta and Omicron variants in hamster	3
Characterization of antibody-dependent cellular cytotoxicity induced by the plasma from persons living with HIV-1 based on target cells with or without CD4 molecules	3
The Leishmania antigen-specific pro-inflammatory response in cutaneous leishmaniasis is linked to disease progression but not to the therapeutic failure of pentavalent antimonials	3
Is there a role for herpes simplex virus type 1 in multiple sclerosis?	3
Had COVID-19 spread in the community before the first confirmed case in Nagasaki, Japan?	3
Detection of Mayaro virus in Aedes aegypti mosquitoes circulating in Goiânia-Goiás-Brazil	3
Nanomotion technology in combination with machine learning: a new approach for a rapid antibiotic susceptibility test for Mycobacterium tuberculosis	3
Virulence potential of the first Corynebacterium mycetoides strain isolated from human urine: a rare species of Corynebacterium	3
Biological differences between FIM2 and FIM3 fimbriae of Bordetella pertussis: not just the serotype	3
Respiratory viruses induce the expression of type I and III IFNs in MSCs through RLR/IRF3 signaling pathways	3
The proteomic analysis uncovers the cellular responses to the African swine fever virus membrane proteins p54, p17, and pB117L	3
Critical roles of parkin and PINK1 in coxsackievirus B3-induced viral myocarditis	3
Blocking pathogenic Leptospira invasion with aptamer molecules targeting outer membrane LipL32 protein	3
Bacterial and host factors involved in zoonotic Streptococcal meningitis	3
Bacterial and fungal co-infections among COVID-19 patients in intensive care unit	3
Knockdown of coagulation factor VII has potential anticoagulant and anti-inflammatory effects in a mouse model of group A streptococcal sepsis	3
Porcine alveolar macrophages and nasal epithelial cells internalize porcine epidemic diarrhea virus (PEDV) but do not support its replication in vitro	3
Staphylococcus aureus NAD kinase is required for envelop and antibiotic stress responses	3
Mycobacterium leprae is able to infect adipocytes, inducing lipolysis and modulating the immune response	3
Comparative virulence of the worldwide ST19 and emergent ST213 genotypes of Salmonella enterica serotype Typhimurium strains isolated from food	2
Biogenic silver nanoparticle exhibits schistosomicidal activity in vitro and reduces the parasitic burden in experimental schistosomiasis mansoni	2
Native human and mouse skin infection models to study Candida auris-host interactions	2
Dopaminergic neuronal regulation determines innate immunity of Caenorhabditis elegans during Klebsiella aerogenes infection	2
HERV reactivation by adenovirus infection is associated with viral immune regulation	2
The multiple frontiers in the study of extracellular vesicles produced by fungi	2
Polymeric promotion	2
Genetic recombination of Orientia tsutsugamushi strains from scrub typhus patients in Guangxi, Southwest China, and the analysis of clinical features	2
The efficacy of the bacteriocinogenic Enterococcus faecalis 14 in the control of induced necrotic enteritis in broilers	2
HIV-1 but not SIVmac239 induces higher interferon-α antiviral state in chronic infected northern pig-tailed macaques (Macaca leonina)	2
Salmonella Typhimurium infection causes defects and fastening of Caenorhabditis elegans developmental stages	2
Gene expression, levels and polymorphism (Ala16Val) of mitochondrial superoxide dismutase in tuberculosis patients of Rajasthan	2
Immunization with a Mu-class glutathione transferase from Echinococcus granulosus induces efficient antibody responses and confers long-term protection against secondary cystic echinococcosis	2
Patient-derived Enterococcus mundtii and its capsular polysaccharides cause depression through the downregulation of NF-κB-involved serotonin and BDNF expression	2
Copyright page Elsevier	2
Mycobiome profiling of nasopharyngeal region of SARS-CoV-2 infected individuals	2
Pseudomonas aeruginosa-derived DnaJ induces TLR2 expression through TLR10-mediated activation of the PI3K-SGK1 pathway in macrophages	2
Alanine racemase a promising Helicobacter pylori drug target inhibited by propanoic acid	2
Saccharomyces boulardii prophylaxis for targeted antibiotics and infectious indications to reduce healthcare facility-onset Clostridioides difficile infection	2
S. aureus biofilm metabolic activity correlates positively with patients’ eosinophil frequencies and disease severity in chronic rhinosinusitis	2
Protection conferred by mucosal novel bivalent Klebsiella pneumoniae vaccine immunization associates with presence of lung CD4+ TRM	2
Cyclosporine A induces Epstein–Barr virus reactivation in tree shrew (Tupaia belangeri chinensis) model	2
Malate:quinone oxidoreductase knockout makes Mycobacterium tuberculosis susceptible to stress and affects its in vivo survival	2
Insight into the structural hierarchy of the protease cascade that regulates the mosquito melanization response	2
The COVID-19 epidemic and other notifiable infectious diseases in China	2
Intragenomic diversity of the small subunit rDNA gene shows limited impact on the pathogenicity of Blastocystis infection in clinical patients	2
Interleukin-6 and -27 as potential novel biomarkers for human pleural tuberculosis regardless of the immunological status	2
Staphylococcus pseudintermedius and Pseudomonas aeruginosa Lubbock Chronic Wound Biofilm (LCWB): a suitable dual-species model for in vitro studies	2
Effects of chronic Helicobacter pylori strain PMSS1 infection on whole brain and gastric iron homeostasis in male INS-GAS mice	2
Microbiota-gut-adipose axis: butyrate-mediated the improvement effect on inflammatory response and fatty acid oxidation dysregulation attenuates obesity in sleep-restricted mice	2
Highlights of the 3rd international BCG symposium: 100th anniversary of the first administration of BCG	2
Production of a monoclonal antibody targeting the SARS-CoV-2 Omicron spike protein and analysis of SARS-CoV-2 Omicron mutations related to monoclonal antibody resistance	2
Molecular characterization of consecutive isolates of OXA-48-producing Klebsiella pneumoniae: changes in the virulome using next-generation sequencing (NGS)	2
Bioluminescence imaging in Paracoccidioides spp.: a tool to monitor the infectious processes	2
Comparative immunogenicity analysis of intradermal versus intramuscular administration of SARS-CoV-2 RBD epitope peptide-based immunogen In vivo	2
Lineage classification and selective site identification of Orthoebolavirus zairense	2
The attenuation of Th1 and Th17 responses via autophagy protects against methicillin-resistant Staphylococcus aureus-induced sepsis	2
Chick heterophils release DNA extracellular traps (DETs) in vitro and in vivo upon Aspergillus fumigatus conidia exposure	2
Topical application of Lactobacilli successfully eradicates Pseudomonas aeruginosa biofilms and promotes wound healing in chronic wounds	2
Identification of defective early immune responses to Burkholderia pseudomallei infection in a diet-induced murine model of type 2 diabetes	2
Retrograde axonal transport property of adeno-associated virus and its possible application in future	2
Mycobacterium tuberculosis ketol-acid reductoisomerase down-regulation affects its ability to persist, and its survival in macrophages and in mice	2
Factors underlying the long-term efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome	2
Systems vaccinology studies – achievements and future potential	2
Butyrate induces oxidative burst mediated apoptosis via Glucose-6-Phosphate Dehydrogenase (G6PDH) in macrophages during mycobacterial infection	2
Efficacy of macozinone in mice with genetically diverse susceptibility to Mycobacterium tuberculosis infection	2
Staphylococcus epidermidis small colony variants, clinically significant quiescent threats for patients with prosthetic joint infection	2
Live Mycobacterium paragordonae induces heterologous immunity of natural killer cells by eliciting type I interferons from dendritic cells via STING-dependent sensing of cyclic-di-GMP	2
Editorial board	2
Prolonged viral shedding and antibody persistence in patients with COVID-19	2
Tim-3 expression is induced by mycobacterial antigens and identifies tissue-resident subsets of MAIT cells from patients with tuberculosis	2
Pertussis toxin-dependent and -independent protection by Bordetella pertussis against influenza	2
Novel serological biomarker panel using protein microarray can distinguish active TB from latent TB infection	2