Journal of Ginseng Research

Papers
(The median citation count of Journal of Ginseng Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
The effects of Korean Red Ginseng-derived components on oligodendrocyte lineage cells: Distinct facilitatory roles of the non-saponin and saponin fractions, and Rb1, in proliferation, differentiation 300
Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability86
Letter to Editor: Antiviral activities of ginseng and its potential benefit against monkeypox virus: A mini review65
Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals53
Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism43
Potential application of ginseng in sepsis:42
Roles of ginsenosides in sepsis42
The potential inhibitory effect of ginsenoside Rh2 on mitophagy in UV-irradiated human dermal fibroblasts41
Panax ginseng as a potential therapeutic for neurological disorders associated with COVID-19; Toward targeting inflammasome41
The effect of ginsenosides on depression in preclinical studies: A systematic review and meta-analysis40
Ginsenoside Rd protects cerebral endothelial cells from oxygen-glucose deprivation/reoxygenation induced pyroptosis via inhibiting SLC5A1 mediated sodium influx36
Systemic and molecular analysis dissect the red ginseng induction of apoptosis and autophagy in HCC as mediated with AMPK36
Effects of Panax species and their bioactive components on allergic airway diseases35
Effect of Korean Red Ginseng on the motor performance and ataxia35
Prophylactic role of Korean Red Ginseng in astrocytic mitochondrial biogenesis through HIF-1α34
Anti-thrombotic effects of ginsenoside Rk3 by regulating cAMP and PI3K/MAPK pathway on human platelets33
Enzymatic bioconversion of ginseng powder increases the content of minor ginsenosides and potentiates immunostimulatory activity33
Ginseng, a promising choice for SARS-COV-2: A mini review32
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells32
A systematic exploration of ginsenoside Rg5 reveals anti-inflammatory functions in airway mucosa cells30
Safety and antifatigue effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial29
Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop28
Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways28
Reciprocal regulation of SIRT1 and AMPK by Ginsenoside compound K impedes the conversion from plasma cells to mitigate for podocyte injury in MRL/lpr mice in a B cell-specific manner28
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization28
The necrotroph Botrytis cinerea promotes disease development in Panax ginseng by manipulating plant defense signals and antifungal metabolites degradation27
Mechanism of Panax notoginseng saponins modulation of miR-214-3p/NR1I3 affecting the pharmacodynamics and pharmacokinetics of warfarin27
Korean Red Ginseng water extract inhibits cadmium-induced lung injury via suppressing MAPK/ERK1/2/AP-1 pathway27
The synergistic effects of Korean Red Ginseng and Cervi Parvum Cornu ameliorating FeCl3-induced arterial thrombosis by downregulating ICAM-1 and VCAM-127
Effects of red ginseng on gut, microbiota, and brain in a mouse model of post-infectious irritable bowel syndrome26
Biodistribution and pharmacokinetic evaluation of Korean Red Ginseng components using radioisotopes in a rat model25
Editorial Board25
Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg123
Emerging evidence that ginseng components improve cognition in subjective memory impairment, mild cognitive impairment, and early Alzheimer's disease dementia23
Ginsenoside Rg5, a potent agonist of Nrf2, inhibits HSV-1 infection-induced neuroinflammation by inhibiting oxidative stress and NF-κB activation23
Corrigendum to “Panax notoginseng saponins promotes angiogenesis after cerebral ischemia-reperfusion injury”[J Ginseng Res 48(6), November 2024, 592–602]22
Ancient herbal therapy: A brief history of Panax ginseng22
Panax ginseng and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects21
Effect of Korean Red Ginseng on metabolic syndrome21
Preparation and evaluation of proliposomes formulation for enhancing the oral bioavailability of ginsenosides21
Corrigendum to “Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models” [J Ginseng Res 46 (2022) 426-434]20
Atypical formations of gintonin lysophosphatidic acids as new materials and their beneficial effects on degenerative diseases20
Corrigendum to Mass spectrometry-based ginsenoside profiling: Recent applications, limitations, and perspectives [J. Ginseng Res. 48(2) (2024) 149–162]20
Respiratory protective effects of Korean Red Ginseng in a mouse model of particulate matter 4-induced airway inflammation20
Effects of Red ginseng on neuroinflammation in neurodegenerative diseases20
Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice20
Gintonin-enriched fraction improves sarcopenia by maintaining immune homeostasis in 20- to 24-month-old C57BL/6J mice20
Rg3-enriched red ginseng extracts enhance apoptosis in CoCl2-stimulated breast cancer cells by suppressing autophagy19
The ways for ginsenoside Rh2 to fight against cancer: the molecular evidences in vitro and in vivo.19
20(S)-ginsenoside Rg3 exerts anti-fibrotic effect after myocardial infarction by alleviation of fibroblasts proliferation and collagen deposition through TGFBR1 signaling pathways19
Inhibitory effect of ginsenglactone A from Panax ginseng on the tube formation of human umbilical vein endothelial cells and migration of human ovarian cancer cells18
Can Panax ginseng help control cytokine storm in COVID-19?18
Ginsenoside Rb3 ameliorates podocyte injury under hyperlipidemic conditions via PPARδ- or SIRT6-mediated suppression of inflammation and oxidative stress18
Panaxcerol D from Panax ginseng ameliorates the memory impairment induced by cholinergic blockade or Aβ25–35 peptide in mice18
Ginsenosides for the treatment of insulin resistance and diabetes: Therapeutic perspectives and mechanistic insights17
Ginsenoside F2 Restrains Hepatic Steatosis and Inflammation by Altering the Binding Affinity of Liver X Receptor Coregulators17
Editorial Board17
Editorial Board16
Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithelial cells16
Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model15
The regulatory role of Korean ginseng in skin cells15
Comment on antiviral activities of ginseng and putative benefits against monkeypox virus15
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades15
The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review15
Korean Red Ginseng inhibits methamphetamine addictive behaviors by regulating dopaminergic and NMDAergic system in rodents15
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy14
Korean red ginseng water extract produces antidepressant-like effects through involving monoamines and brain-derived neurotrophic factor in rats14
The molecular mechanism of ginsenoside Rh2 and its octyl ester derivative on anti-angiogenesis in cancer treatment: The battle between PI3K and ROS14
The potential of Panax notoginseng against COVID-19 infection14
Ginseng as a therapeutic target to alleviate gut and brain diseases via microbiome regulation14
Editorial Board14
Ginsenoside Rg1 suppresses cancer cell proliferation through perturbing mitotic progression14
Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGE2 pathways13
Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy13
Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice13
Skin wound healing effects of (+)-syringaresinol from ginseng berry13
Newly identified maltol derivatives in Korean Red Ginseng and their biological influence as antioxidant and anti-inflammatory agents13
Influence of the plant growth promoting Rhizobium panacihumi on aluminum resistance in Panax ginseng13
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways13
The necessity of eliminating the interference of panaxatriol saponins to maximize the preventive effect of panaxadiol saponins against Parkinson's disease in rats12
Rg3-enriched red ginseng extract promotes lung cancer cell apoptosis and mitophagy by ROS production12
Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing12
Pharmacological potential of ginseng and ginsenosides in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis12
DK-MGAR101, an extract of adventitious roots of mountain ginseng, improves blood circulation by inhibiting endothelial cell injury, platelet aggregation, and thrombus formation12
Visualizing the distributions and spatiotemporal changes of metabolites in Panax notoginseng by MALDI mass spectrometry imaging12
Structural analysis, anti-inflammatory activity of the main water-soluble acidic polysaccharides (AGBP-A3) from Panax quinquefolius L berry12
Ginseng polysaccharides: Potential antitumor agents11
High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture11
Effect of red ginseng on visual function and vision-related quality of life in patients with glaucoma11
Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-15211
The effects of Korean Red Ginseng on stress-related neurotransmitters and gene expression: A randomized, double-blind, placebo-controlled trial11
Korean Red Ginseng saponin fraction exerts anti-inflammatory effects by targeting the NF-κB and AP-1 pathways11
Microbiota, co-metabolites, and network pharmacology reveal the alteration of the ginsenoside fraction on inflammatory bowel disease11
Synthesis of ginsenoside Rb1-imprinted magnetic polymer nanoparticles for the extraction and cellular delivery of therapeutic ginsenosides11
Ginsenoside-Re-rich ethanol extract of Panax ginseng berry enhances healthspan extension via mitostasis and NAD metabolism10
Corrigendum to “Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway” [J Ginseng Res 46 (2022) 156–166]10
A review of the immunomodulatory activities of polysaccharides isolated from Panax species10
Corrigendum to’ Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice’ [Journal of Ginseng Research Volume 46, Issue 610
Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway10
Corrigendum to “Korean red ginseng extract ameliorates melanogenesis in humans and induces anti-photo aging effects in ultraviolet B-irradiated hairless mice” [J Ginseng Res 44 (2020) 496–505]10
Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat10
Corrigendum to ‘Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice’[Journal of Ginseng Research Volume 47, Issue 2, 10
Rare ginsenosides transformed from stems and leaves of Panax ginseng reverse obesity by promoting browning of white fat through PKA/CREB pathway via REGγ negative regulation10
Comparative transcriptome and metabolome analyses of four Panax species explore the dynamics of metabolite biosynthesis9
Compound K ameliorates airway inflammation and mucus secretion through the regulation of PKC signaling in vitro and in vivo9
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt19
Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities9
The anti-platelet activity of panaxadiol fraction and panaxatriol fraction of Korean Red Ginseng in vitro and ex vivo9
Improvement of antithrombotic activity of red ginseng extract by nanoencapsulation using chitosan and antithrombotic cross-linkers: polyglutamic acid and fucoidan9
Effects of Panax ginseng and ginsenosides on oxidative stress and cardiovascular diseases: pharmacological and therapeutic roles9
Ginsenoside 20(S)-Rg3 reduces KIF20A expression and promotes CDC25A proteasomal degradation in epithelial ovarian cancer8
Production and characterization of lentivirus vector-based SARS-CoV-2 pseudoviruses with dual reporters: Evaluation of anti-SARS-CoV-2 viral effect of Korean Red Ginseng8
Synergetic effect of soluble whey protein hydrolysate and Panax ginseng berry extract on muscle atrophy in hindlimb-immobilized C57BL/6 mice8
Metabolism and drug interactions of Korean ginseng based on the pharmacokinetic properties of ginsenosides: Current status and future perspectives8
20(S)- Protopanaxadiol suppresses hepatic stellate cell activation via WIF1 demethylation-mediated inactivation of the Wnt/β-catenin pathway8
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway8
Botrytis cinerea hypovirulent strain △BcSpd1 induced Panax ginseng defense8
Effects of red ginseng extract on gut microbial distribution8
Impact of HIV-1 subtypes on gross deletion in the nef gene after Korean Red Ginseng treatment8
Ginsenoside F1 attenuates pirarubicin-induced cardiotoxicity by modulating Nrf2 and AKT/Bcl-2 signaling pathways8
The non-saponin fraction of Korean Red Ginseng ameliorates sarcopenia by regulating immune homeostasis in 22–26-month-old C57BL/6J mice8
Enhancement of seed germination and microbial disinfection on ginseng by cold plasma treatment8
A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline8
Protective effects of Panax ginseng berry extract on blue light-induced retinal damage in ARPE-19 cells and mouse retina7
Therapeutic applications of ginseng for skeletal muscle-related disorder management7
Siderophore-producing rhizobacteria reduce heavy metal-induced oxidative stress in Panax ginseng Meyer7
Ginsenoside compound K reduces the progression of Huntington's disease via the inhibition of oxidative stress and overactivation of the ATM/AMPK pathway7
Korean Red Ginseng reduces chronic social defeat stress-induced mood disorders via N-methyl-D-aspartate receptor modulation in mice7
Ginsenoside Rg3-enriched Korean Red Ginseng extract attenuates Non-Alcoholic Fatty Liver Disease by way of suppressed VCAM-1 expression in liver sinusoidal endothelium7
Integration of virtual screening and proteomics reveals potential targets and pathways for ginsenoside Rg1 against myocardial ischemia7
Korean Red Ginseng suppresses emphysematous lesions induced by cigarette smoke condensate through inhibition of macrophage-driven apoptosis pathways7
Korean red ginseng suppresses mitochondrial apoptotic pathway in denervation-induced skeletal muscle atrophy7
Foeniculum vulgare essential oil nanoemulsion inhibits Fusarium oxysporum causing Panax notoginseng root-rot disease7
Antiviral activities of ginseng and its potential and putative benefits against monkeypox virus: A mini review7
Ginsenoside Rg5 promotes muscle regeneration via p38MAPK and Akt/mTOR signaling7
Ginsenoside Rg1 promotes neurite growth of retinal ganglion cells through cAMP/PKA/CREB pathways7
Proteomic analysis for the effects of non-saponin fraction with rich polysaccharide from Korean Red Ginseng on Alzheimer's disease in a mouse model7
Ginsenoside Rg1 enhances the healing of injured tendon in achilles tendinitis through the activation of IGF1R signaling mediated by oestrogen receptor6
Stem-and-leaf of new hydroponically-cultured ginseng cultivar K-1: A sustainable and innovative resource of ginsenosides for anti-inflammatory agents6
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2” [J. Ginseng Res. 47 (1) (January 6
Compositional changes and physiological activities of fresh ginseng extracts prepared at various temperatures in subcritical water6
Ginsenosides Rg1 regulate lipid metabolism and temperature adaptation in Caenorhabditis elegans6
Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134–mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression6
Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models6
Targeting the DNA damage response (DDR) of cancer cells with natural compounds derived from Panax ginseng and other plants6
Total saponins from Panax Japonicus regulate the ferritin heavy chain to reduce inflammation in aging adipose tissue by mediating iron metabolism6
Corrigendum to “Ginsenoside compound K protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury via inhibition of nuclear factor-kB, p38, and JNK MAPK pa6
Methanol-involved heterogeneous transformation of ginsenoside Rb1 to rare ginsenosides using heteropolyacids embedded in mesoporous silica with HPLC-MS investigation6
Systematic exploration of therapeutic effects and key mechanisms of Panax ginseng using network-based approaches6
Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway5
Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells5
Korean Red ginseng-induced astrocytic HIF-1α: A key regulator of neuroglobin derived from neural stem cell differentiation in physiologic retina and brain5
Growth promotion effect of red ginseng dietary fiber to probiotics and transcriptome analysis of Lactiplantibacillus plantarum5
Syringaresinol derived from Panax ginseng berry attenuates oxidative stress-induced skin aging via autophagy5
The pharmacological role of Ginsenoside Rg3 in liver diseases: A review on molecular mechanisms5
Gintonin influences the morphology and motility of adult brain neurons via LPA receptors5
Effects of Korean red ginseng on T-cell repopulation after autologous hematopoietic stem cell transplantation in childhood cancer patients5
Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells5
Saponin attenuates diesel exhaust particle (DEP)-induced MUC5AC expression and pro-inflammatory cytokine upregulation via TLR4/TRIF/NF-κB signaling pathway in airway epithelium and ovalbumin (OVA)-sen5
Gypenoside XVII protects against myocardial ischemia and reperfusion injury by inhibiting ER stress–induced mitochondrial injury5
Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD5
Cognitive function improvement effects of gintonin-enriched fraction in subjective memory impairment: An assessor- and participant-blinded placebo-controlled study5
The dehiscence process in Panax ginseng seeds and the stigmasterol biosynthesis pathway in terms of metabolomics5
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway5
Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss in mice5
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway5
Ginsenoside Rg1 reduces cardiac inflammation against myocardial ischemia/reperfusion injury by inhibiting macrophage polarization4
Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction4
Gintonin-enriched fraction protects against sarcopenic obesity by promoting energy expenditure and attenuating skeletal muscle atrophy in high-fat diet-fed mice4
Corona-Cov-2 (COVID-19) and ginseng: Comparison of possible use in COVID-19 and influenza4
Safety of red ginseng and herb extract complex (RHC) in menopausal women: A randomized, double-blind, placebo-controlled trial4
Ginsenoside Rk1 inhibits HeLa cell proliferation through an endoplasmic reticulum signaling pathway4
Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice4
20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo4
Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation4
Panax ginseng: Inflammation, platelet aggregation, thrombus formation, and atherosclerosis crosstalk4
Preventive effects of ginseng against atherosclerosis and subsequent ischemic stroke: A randomized controlled trial (PEGASUS trial)4
Dexamethasone-induced muscle atrophy and bone loss in six genetically diverse collaborative cross founder strains demonstrates phenotypic variability by Rg3 treatment4
Neuroprotective effects of Korean White ginseng and Red ginseng in an ischemic stroke mouse model4
Gintonin facilitates brain delivery of donepezil, a therapeutic drug for Alzheimer disease, through lysophosphatidic acid 1/3 and vascular endothelial growth factor receptors4
Methods on improvements of the poor oral bioavailability of ginsenosides: Pre-processing, structural modification, drug combination, and micro- or nano- delivery system4
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