Journal of Ginseng Research

Papers
(The median citation count of Journal of Ginseng Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop98
Corrigendum to “Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models” [J Ginseng Res 46 (2022) 426-434]82
The necrotroph Botrytis cinerea promotes disease development in Panax ginseng by manipulating plant defense signals and antifungal metabolites degradation67
Ginsenoside Rh2 alleviates inflammatory response and enhances motor function recovery in spinal cord injury mice via the ROS/MAPK14 signaling pathway59
Korean Red Ginseng water extract inhibits cadmium-induced lung injury via suppressing MAPK/ERK1/2/AP-1 pathway55
Anti-thrombotic effects of ginsenoside Rk3 by regulating cAMP and PI3K/MAPK pathway on human platelets53
Ginsenoside Rb1 attenuates coronary microvascular inflammatory injury via NDUFS4-SIRT5-DUSP1-mediated mitochondrial quality control in a murine ischemia-reperfusion model51
Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg150
Panax ginseng and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects50
The antitumor effects and apoptotic mechanism of 20(S)-Protopanaxadiol in acute myeloid leukemia48
Ginsenoside Rg5, a potent agonist of Nrf2, inhibits HSV-1 infection-induced neuroinflammation by inhibiting oxidative stress and NF-κB activation45
Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways43
Korean Red Ginseng saponin fraction exerts anti-inflammatory effects by targeting the NF-κB and AP-1 pathways42
Ginsenoside F2 Restrains Hepatic Steatosis and Inflammation by Altering the Binding Affinity of Liver X Receptor Coregulators40
Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway38
Influence of the plant growth promoting Rhizobium panacihumi on aluminum resistance in Panax ginseng38
Ginsenoside Rg1 suppresses cancer cell proliferation through perturbing mitotic progression36
Panaxcerol D from Panax ginseng ameliorates the memory impairment induced by cholinergic blockade or Aβ25–35 peptide in mice36
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt135
Inhibitory effect of ginsenglactone A from Panax ginseng on the tube formation of human umbilical vein endothelial cells and migration of human ovarian cancer cells34
A review of the immunomodulatory activities of polysaccharides isolated from Panax species34
Ginsenoside Rg3-enriched Korean Red Ginseng extract attenuates Non-Alcoholic Fatty Liver Disease by way of suppressed VCAM-1 expression in liver sinusoidal endothelium33
Enhancement of seed germination and microbial disinfection on ginseng by cold plasma treatment33
Production and characterization of lentivirus vector-based SARS-CoV-2 pseudoviruses with dual reporters: Evaluation of anti-SARS-CoV-2 viral effect of Korean Red Ginseng33
Ginsenoside Rg5 modulates the TLR4 and BCL-2 pathways by inhibiting NOX1, thereby alleviating inflammation, apoptosis and pyroptosis in hyperuricemia nephropathy33
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway33
Gintonin influences the morphology and motility of adult brain neurons via LPA receptors32
Protective effects of Panax ginseng berry extract on blue light-induced retinal damage in ARPE-19 cells and mouse retina32
Korean Red Ginseng slows coreceptor switch in HIV-1 infected patients28
Safety of red ginseng and herb extract complex (RHC) in menopausal women: A randomized, double-blind, placebo-controlled trial27
Effects of Korean red ginseng on T-cell repopulation after autologous hematopoietic stem cell transplantation in childhood cancer patients27
Korean Red Ginseng and Rb1 restore altered social interaction, gene expressions in the medial prefrontal cortex, and gut metabolites under post-weaning social isolation in mice27
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2”[J Ginseng Res 45(5) September 20226
Assessing systemic, developmental, and reproductive toxicity and estrogenicity of Korean red ginseng extract G1899 in juvenile Sprague-Dawley Rats25
Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway25
Compound K-enriched Korean red ginseng prevents lung cancer progression by targeting cancer cells and fibroblasts25
Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD25
Antiviral effects of Korean Red Ginseng on human coronavirus OC4324
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway24
Korean Red Ginseng extract treatment prevents post-antibiotic dysbiosis-induced bone loss in mice24
The dehiscence process in Panax ginseng seeds and the stigmasterol biosynthesis pathway in terms of metabolomics24
20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo24
Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy24
Ginsenoside Re prevents 3-methyladenine-induced catagen phase acceleration by regulating Wnt/β-catenin signaling in human dermal papilla cells23
20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL323
Ginsenoside compound K reduces ischemia/reperfusion-induced neuronal apoptosis by inhibiting PTP1B-mediated IRS1 tyrosine dephosphorylation23
Evaluation of storage period of fresh ginseng for quality improvement of dried and red processed varieties23
Identification and confirmation of 14-3-3 ζ as a novel target of ginsenosides in brain tissues22
Long-term administration of red ginseng non-saponin fraction rescues the loss of skeletal muscle mass and strength associated with aging in mice22
Neuroprotective effect of Korean Red Ginseng against single prolonged stress-induced memory impairments and inflammation in the rat brain associated with BDNF expression21
Enhancing effect of Panax ginseng on Zip4-mediated zinc influx into the cytosol20
Ginseng root-derived exosome-like nanoparticles protect skin from UV irradiation and oxidative stress by suppressing activator protein-1 signaling and limiting the generation of reactive oxygen specie20
Maltol, a compound in Korean Red Ginseng, attenuates the Staphylococcus aureus–induced inflammasome activation in the skin20
Corrigendum to ‘Reciprocal regulation of SIRT1 and AMPK by Ginsenoside compound K impedes the conversion from plasma cells to mitigate for podocyte injury in MRL/lpr mice in a B cell-specific manner’ 20
Effect of Korean Red Ginseng through comparative analysis of cardiac gene expression in db/db mice20
Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes20
Comprehensive understanding and underlying molecular mechanisms of the adaptogenic effects of Panax ginseng19
Role of ginseng in the neurovascular unit of neuroinflammatory diseases focused on the blood-brain barrier19
Ginsenoside Rc prevents dexamethasone-induced muscle atrophy and enhances muscle strength and motor function19
Editorial Board19
Inhibitory activity of gintonin on inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and collagen-induced arthritis in mice19
Bacterial endophytes from ginseng and their biotechnological application18
Sustainable production of natural products using synthetic biology: Ginsenosides18
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway18
Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NF-κB signaling pathway18
Corrigendum to “Panax notoginseng saponins promotes angiogenesis after cerebral ischemia-reperfusion injury”[J Ginseng Res 48(6), November 2024, 592–602]17
Biodistribution and pharmacokinetic evaluation of Korean Red Ginseng components using radioisotopes in a rat model17
Prophylactic role of Korean Red Ginseng in astrocytic mitochondrial biogenesis through HIF-1α17
Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals17
Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability17
Editorial Board16
Panax ginseng as a potential therapeutic for neurological disorders associated with COVID-19; Toward targeting inflammasome16
Comment on antiviral activities of ginseng and putative benefits against monkeypox virus16
Effect of Korean Red Ginseng on metabolic syndrome16
Effects of Panax species and their bioactive components on allergic airway diseases16
Editorial Board16
Effects of red ginseng on gut, microbiota, and brain in a mouse model of post-infectious irritable bowel syndrome16
20(S)-ginsenoside Rg3 exerts anti-fibrotic effect after myocardial infarction by alleviation of fibroblasts proliferation and collagen deposition through TGFBR1 signaling pathways15
Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat15
Effects of Korean red ginseng on auditory, cognitive, and liver functions in a naturally aged mouse model15
Ginsenoside Re promotes osteogenic differentiation via BMP2/p38 pathway in vivo and in vitro15
Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice14
Microbiota, co-metabolites, and network pharmacology reveal the alteration of the ginsenoside fraction on inflammatory bowel disease14
Structural analysis, anti-inflammatory activity of the main water-soluble acidic polysaccharides (AGBP-A3) from Panax quinquefolius L berry14
Rg3-enriched red ginseng extracts enhance apoptosis in CoCl2-stimulated breast cancer cells by suppressing autophagy14
Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing14
The ways for ginsenoside Rh2 to fight against cancer: the molecular evidences in vitro and in vivo.14
Compositional changes and physiological activities of fresh ginseng extracts prepared at various temperatures in subcritical water13
Antiviral activities of ginseng and its potential and putative benefits against monkeypox virus: A mini review13
Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models13
Comparative transcriptome and metabolome analyses of four Panax species explore the dynamics of metabolite biosynthesis13
Korean Red ginseng supplements improve quality of life in patients with mild chronic pancreatitis symptoms: A prospective clinical trial13
Impact of HIV-1 subtypes on gross deletion in the nef gene after Korean Red Ginseng treatment13
Corrigendum to “Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2” [J. Ginseng Res. 47 (1) (January 13
Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134–mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression13
Ginsenoside Rk1 inhibits HeLa cell proliferation through an endoplasmic reticulum signaling pathway12
Cognitive function improvement effects of gintonin-enriched fraction in subjective memory impairment: An assessor- and participant-blinded placebo-controlled study12
Inhalation of panaxadiol alleviates lung inflammation via inhibiting TNFA/TNFAR and IL7/IL7R signaling between macrophages and epithelial cells12
Korean Red Ginseng alleviates dextran sodium sulfate-induced colitis through gut microbiota modulation in mice12
Red ginseng extract inhibits lipopolysaccharide-induced platelet–leukocyte aggregates in mice12
Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice11
Ginseng and ginseng byproducts for skincare and skin health11
Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation11
Synergistic effects of ginsenoside Rb1 and peroxiredoxin 6 in enhancing myocardial injury treatment through anti-inflammatory, anti-oxidative, and anti-apoptotic mechanisms11
Growth promotion effect of red ginseng dietary fiber to probiotics and transcriptome analysis of Lactiplantibacillus plantarum11
Visualization of the binding between gintonin, a Panax ginseng-derived LPA receptor ligand, and the LPA receptor subtypes and transactivation of the EGF receptor11
Phenological growth stages of Korean ginseng (Panax ginseng) according to the extended BBCH scale10
Potential benefits of ginseng against COVID-19 by targeting inflammasomes10
P-hydroxybenzoic acid positively affect the Fusarium oxysporum to stimulate root rot in Panax notoginseng10
Ginsenoside F1 Attenuates Eosinophilic Inflammation in Chronic Rhinosinusitis by Promoting NK Cell Function10
The beneficial potential of ginseng for menopause10
The effects of Korean Red Ginseng on heme oxygenase-1 with a focus on mitochondrial function in pathophysiologic conditions10
Ginsenoside compound K ameliorates palmitate-induced atrophy in C2C12 myotubes via promyogenic effects and AMPK/autophagy-mediated suppression of endoplasmic reticulum stress10
Korean Red Ginseng attenuates ultraviolet-mediated inflammasome activation in keratinocytes10
Effects of red ginseng oil(KGC11o) on testosterone-propionate-induced benign prostatic hyperplasia10
Korean Red Ginseng and Rb1 facilitate remyelination after cuprizone diet-induced demyelination10
Red ginseng oil promotes hair growth and protects skin against UVC radiation10
Effect of ginseng and ginsenosides on attention deficit hyperactivity disorder: A systematic review10
Therapeutic potential of ginsenosides in circadian rhythm-based skin disorders10
Editorial Board9
Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism9
The effects of Korean Red Ginseng on stress-related neurotransmitters and gene expression: A randomized, double-blind, placebo-controlled trial9
High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture9
Corrigendum to’ Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice’ [Journal of Ginseng Research Volume 46, Issue 69
Letter to Editor: Antiviral activities of ginseng and its potential benefit against monkeypox virus: A mini review9
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways9
Skin wound healing effects of (+)-syringaresinol from ginseng berry9
Can Panax ginseng help control cytokine storm in COVID-19?9
Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy9
Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease9
The necessity of eliminating the interference of panaxatriol saponins to maximize the preventive effect of panaxadiol saponins against Parkinson's disease in rats9
Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-1529
Metabolism and drug interactions of Korean ginseng based on the pharmacokinetic properties of ginsenosides: Current status and future perspectives9
Synergetic effect of soluble whey protein hydrolysate and Panax ginseng berry extract on muscle atrophy in hindlimb-immobilized C57BL/6 mice8
Gintonin, a Panax ginseng-derived LPA receptor ligand, attenuates kainic acid-induced seizures and neuronal cell death in the hippocampus via anti-inflammatory and anti-oxidant activities8
Methanol-involved heterogeneous transformation of ginsenoside Rb1 to rare ginsenosides using heteropolyacids embedded in mesoporous silica with HPLC-MS investigation8
Regulation of appetite-related neuropeptides by Panax ginseng: A novel approach for obesity treatment8
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway8
Foeniculum vulgare essential oil nanoemulsion inhibits Fusarium oxysporum causing Panax notoginseng root-rot disease8
The clearing-up of misunderstanding on body temperature changes and heat responses after Panax ginseng or Panax quinquefolium intake8
Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction8
Recent progress (2015–2020) in the investigation of the pharmacological effects and mechanisms of ginsenoside Rb1, a main active ingredient in Panax ginseng Meyer8
Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells8
Ginsenoside Rg5 promotes muscle regeneration via p38MAPK and Akt/mTOR signaling8
Ginsenoside 20(S)-Rg3 reduces KIF20A expression and promotes CDC25A proteasomal degradation in epithelial ovarian cancer8
Korean Red Ginseng extract ameliorates demyelination by inhibiting infiltration and activation of immune cells in cuprizone-administrated mice8
Enhanced immunity effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial8
Ginsenoside compound K reduces the progression of Huntington's disease via the inhibition of oxidative stress and overactivation of the ATM/AMPK pathway8
Effect of coadministration of enriched Korean Red Ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L) on cardiometabolic outcomes in type-2 diabetes: A randomized controlled trial7
Comparative antiplatelet and antithrombotic effects of red ginseng and fermented red ginseng extracts7
Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR27
Review of ginsenosides targeting mitochondrial function to treat multiple disorders: Current status and perspectives7
Panax ginseng exerts cardioprotective effect post myocardial infarction by attenuating myocardial fibrosis and inflammation through SIRT1 signaling pathways7
Nitrate enhances the secondary growth of storage roots in Panax ginseng7
COVID-19 infection and ginseng: Predictive influenza virus strains and non-predictive COVID-19 vaccine strains7
Ginsenoside Rg1 exerts antidepressant effect by regulating hepatic kynurenine metabolism through promoting the interaction between HNF4α and PGC1α7
Identification of a key signaling network regulating perennating bud dormancy in Panax ginseng7
In silico investigation of Panax ginseng lead compounds against COVID-19 associated platelet activation and thromboembolism7
Effects of Panax ginseng on hyperglycemia, hypertension, and hyperlipidemia: A systematic review and meta-analysis7
Human disease-related long noncoding RNAs: Impact of ginsenosides7
20(S)-Ginsenoside Rh2 induces apoptosis and autophagy in melanoma cells via suppressing Src/STAT3 signaling7
Saengmaeksan, a traditional herbal formulation consisting of Panax ginseng, ameliorates hyperuricemia by inhibiting xanthine oxidase activity and enhancing urate excretion in rats6
Potential application of ginseng in sepsis:6
Roles of ginsenosides in sepsis6
The potential inhibitory effect of ginsenoside Rh2 on mitophagy in UV-irradiated human dermal fibroblasts6
Ginsenoside Rb2: A review of pharmacokinetics and pharmacological effects6
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization6
Safety and antifatigue effect of Korean Red Ginseng capsule: A randomized, double-blind and placebo-controlled clinical trial6
The effect of ginsenosides on depression in preclinical studies: A systematic review and meta-analysis6
Korean Red Ginseng, a regulator of NLRP3 inflammasome, in the COVID-19 pandemic6
Modification of ginsenoside saponin composition via the CRISPR/Cas9-mediated knockout of protopanaxadiol 6-hydroxylase gene in Panax ginseng6
Amelioration of colitis progression by ginseng-derived exosome-like nanoparticles through suppression of inflammatory cytokines6
Emerging evidence that ginseng components improve cognition in subjective memory impairment, mild cognitive impairment, and early Alzheimer's disease dementia6
Enzymatic bioconversion of ginseng powder increases the content of minor ginsenosides and potentiates immunostimulatory activity6
Effects of Red ginseng on neuroinflammation in neurodegenerative diseases5
Targeting the DNA damage response (DDR) of cancer cells with natural compounds derived from Panax ginseng and other plants5
Rare ginsenosides transformed from stems and leaves of Panax ginseng reverse obesity by promoting browning of white fat through PKA/CREB pathway via REGγ negative regulation5
Ginsenoside Rg2, a principal effective ingredient of Panax ginseng, attenuates DSS-induced ulcerative colitis through NF-κB/NLRP3 pathway5
Effects of red ginseng extract on gut microbial distribution5
Ginsenoside Rg1 enhances the healing of injured tendon in achilles tendinitis through the activation of IGF1R signaling mediated by oestrogen receptor5
Respiratory protective effects of Korean Red Ginseng in a mouse model of particulate matter 4-induced airway inflammation5
The molecular mechanism of ginsenoside Rh2 and its octyl ester derivative on anti-angiogenesis in cancer treatment: The battle between PI3K and ROS5
Corrigendum to “Ginsenoside compound K protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury via inhibition of nuclear factor-kB, p38, and JNK MAPK pa5
Ginsenosides for the treatment of insulin resistance and diabetes: Therapeutic perspectives and mechanistic insights5
Effects of Panax ginseng and ginsenosides on oxidative stress and cardiovascular diseases: pharmacological and therapeutic roles5
Ginsenoside Rg1 promotes neurite growth of retinal ganglion cells through cAMP/PKA/CREB pathways5
Visualizing the distributions and spatiotemporal changes of metabolites in Panax notoginseng by MALDI mass spectrometry imaging5
Korean Red Ginseng inhibits methamphetamine addictive behaviors by regulating dopaminergic and NMDAergic system in rodents5
Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice5
Corrigendum to ‘Effect of fermented red ginseng on gut microbiota dysbiosis- or immobilization stress-induced anxiety, depression, and colitis in mice’[Journal of Ginseng Research Volume 47, Issue 2, 5
The anti-platelet activity of panaxadiol fraction and panaxatriol fraction of Korean Red Ginseng in vitro and ex vivo5
Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithelial cells5
Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy5
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