Biotechnology and Bioprocess Engineering

Article	Citations
Homotaurine exhibits contrasting effects of DRD1-mediated thermogenesis-related regulators in C2C12 myoblasts and 3T3−L1 white adipocytes	64
Improvement of menopausal symptoms by oat hull extracts in ovariectomized animal model	45
Improved enzyme-linked immunosorbent assay using surface-adhesive antibody-oriented immobilizing biolinker: a proof-of-concept study	41
The latest techniques for inducing macrophage differentiation	25
Non-invasive online monitoring of polyol lipid production with Aureobasidium pullulans using fluorescence measurement	23
Inhibition of Cyclopropane Fatty Acid Synthesis in the Membrane of Halophilic Halomonas socia CKY01 by Kanamycin	23
L-Asparaginase production by Neurospora sitophila SK5: from identification to bioprocess optimization	23
Elucidation of the Mechanism and Kinetics of Ultrasonic Extraction of Paclitaxel from Plant Cell Cultures of Taxus chinensis	19
Identification and characterization of l-ribulose 3-epimerase from Leifsonia aquatica and its application in d-allulose production	19
Development of a glucose enzyme fuel cell based on thin film electrode using biocatalysts	18
CircBRMS1L Participates in Lipopolysaccharide-induced Chondrocyte Injury via the TLR4/NF-κB Pathway through Serving as a miR-142-5p Decoy	17
Convolution Neural Network Approaches for Cancer Cell Image Classification	17
Effect of reduced atmospheric pressures on the morphology and astaxanthin biosynthesis of microalga Haematococcus lacustris	17
Impact of the Synthetic Scaffold Strategy on the Metabolic Pathway Engineering	16
Mechanistic Insight into Phenolic Compounds Toxicity and State-of-the-art Strategies for Enhancing the Tolerance of Escherichia coli to Phenolic Compounds	16
C13-apocarotenoids biosynthesis with engineered microbes	16
A comparison of metabolic engineering strategies applied in Yarrowia lipolytica for β-carotene production	16
Bioprocess Challenges in Purification of Therapeutic Protein Charge Variants	16
Multi-bioinspired Sprayable Nanotherapeutics for Tumor-Specific Focal Cancer Therapy	16
Novel Synthesis of Ca2+-Doped MgAl2O3-G-SiO2 Mesoporous Nanospheres toward Sensing Effects for Selective Electrochemical Performance of Azithromycin	16
The Enzymatic Process of Macroalgae for Conversion into High-tech Bioproducts	15
Recent Progress in Microalgal Squalene Production and Its Cosmetic Application	15
Recent Advances in the Utilization of Brown Macroalgae as Feedstock for Microbial Biorefinery	15
Trans-anethole Induces Thermogenesis via Activating SERCA/SLN Axis in C2C12 Muscle Cells	14
Erratum to: Optimization of Vacuum Frying Process for Sweet Potato Chip Manufacturing Using Response Surface Methodology and Artificial Neural Network Model	14

Assessment of Damnacanthus major Siebold & Zucc callus for antioxidative and moisturizing capacities using an artificial skin alternative	14
L-Dihydroxyphenylalanine (L-Dopa) Induces Brown-like Phenotype in 3T3-L1 White Adipocytes via Activation of Dopaminergic and β3-adrenergic Receptors	14
Cyclic AMP Responsive Element Binding Protein 3-like 4/AarF Domain Containing Kinase 5 Axis Facilitates Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells by Modulating the TGFβ Pathwa	14
Production of Tagatose by Whole-cell Bioconversion from Fructose Using Corynebacterium glutamicum	14
An Aligned Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Scaffold Fixed with Fibronectin to Enhance the Attachment and Growth of Human Endothelial Progenitor Cells	13
Albumin: A Multi-talented Clinical and Pharmaceutical Player	13
Drug-eluting Microneedles Embedded with Nanoparticles for Anti-inflammatory Purposes	13
A Review of Microbial Molecular Profiling during Biomass Valorization	13
Efficient production of 1,3-propanediol from glycerol by a newly isolated soil bacterium using fed-batch fermentation	13
Extracellular Fenton-like reaction via glucose oxidase-loaded nanocapsule to Fe₃O₄ nanoparticle cascades enables enhanced cancer cell killing	13
Fabrication of folic acid–cysteamine-modified silver nanoparticles as promising contrast agent for computed tomography imaging	13
3D microcapsules for human bone marrow-derived mesenchymal stem cell biomanufacturing in a vertical-wheel bioreactor	13
Improving the Thermostability of α-Glucosidase from Xanthomonas campestris through Proline Substitutions Guided by Semi-rational Design	13
Automatic cancer nuclei segmentation on histological images: comparison study of deep learning methods	12
Sodium-potassium Adenosine Triphosphatase α2 Subunit (ATP1A2) Negatively Regulates UCP1-dependent and UCP1-independent Thermogenesis in 3T3-L1 Adipocytes	12
Bioreducible polysorbate-based micelles encapsulating mitochondria-targeting sonosensitizers for efficient chemo-sonodynamic cancer therapy	12
Inhibiting angiogenesis and osteogenesis by targeted regulation of KLK4 via the exosomal MiR-422a derived from bone mesenchymal stem cells	12
Ceramide’s Role and Biosynthesis: A Brief Review	11
Continuous cell recycling in methylotrophic yeast Pichia pastoris to enhance product yields: a case study with Yarrowia lipolytica lipase Lip2	11
Lentiviral Surface Engineering via Tris(2-Carboxyethyl)Phosphine-mediated HEK-293T Cell Modification	11
Current Updates on COVID-19 Vaccines and Therapeutics: As of June 2022	11
Metallic Vessel with Mesh Culture Surface Fabricated Using Three-dimensional Printing Engineers Tissue Culture Environment	11
Cell-free Biosynthesis of Peptidomimetics	11
Erratum to: Impact of the Synthetic Scaffold Strategy on the Metabolic Pathway Engineering	11
Functional expression of loosenins in Escherichia coli and their characterization for the application to cellulose saccharification	11
Zero-valent Iron Enhances Acetate and Butyrate Production from Carbon Monoxide by Fonticella tunisiensis HN43	11
Bioimprinted Aspergillus niger Lipase Combined with Adsorption Immobilization by Resin and Its Experiment in Catalytic Synthesis of Sucrose-6-acetate	11
Agarwood Pill Enhances Immune Function in Cyclophosphamide-induced Immunosuppressed Mice	11
Material technical guide for on-demand additive manufacturing production of bioreactors	10
Ultrasound- and Negative Pressure-assisted Fractional Precipitation of Paclitaxel from Taxus chinensis	10
Evaluation of hair growth-promoting, anti-inflammatory, and 5α-reductase inhibitory effects of Spirulina extract using in vitro and in vivo models	10
A study on the relationship between MDR1 mutation and ex vivo drug sensitivities of canine lymphomas	10
Wound healing-promoting effects of flavonoid from Quercus Mongolica via 15-PGDH Inhibition and collagen biosynthesis	10
Enhancing the Thermostability of Cellulase from Clostridium thermocellum via Salt Bridge Interactions	10
Candida rugosa Lipase Immobilization on Fe3O4 Coated Carboxyl Functionalised Multiwalled Carbon Nanotubes for Production of Food Flavour Esters	10
Investigation of β-phenylethanol production by a wild-type Pichia kudriavzevii isolated from jiuqu of rice-flavor baijiu	10
Green synthesis of gold nanoparticles using Acorus calamus leaf extract and study on their anti-alzheimer potential	10
Selective Extraction of Chlorophyll a/Photosystem Polypeptides from Spirulina maxima Using Aqueous Two Phase Extraction	10
Redox switch protein Hsp33 has a novel zinc-dependent DNA binding function under cold stress in Escherichia coli	9
Promotion of germination and astaxanthin production in Haematococcus pluvialis by pressurization of seed cysts	9
Identification Process and Physiological Properties of Transporters of Carboxylic Acids in Escherichia coli	9
Bone enhancement effect of microalgae-derived unsaponifiable matters on osteoblast through differentiation regulation	9
Mixotrophic production of bioplastics from agricultural feedstocks by a mutant strain of Cupriavidus necator	9
Publisher Erratum to: Effects of gltA and arcA Mutations on Biomass and 1,3-Propanediol Production in Klebsiella pneumoniae	9
Bioactive materials and drug delivery in 3D printing for bone regeneration	9
Photothermal heating of cell-free reactions for on-site production of recombinant proteins	9
Recycle of sugarcane molasses by Aurantiochytrium sp. for high-value docosahexaenoic acid	9
Sensitive detection of SARS-CoV2 spike antibodies by a paper-based polypyrrole/reduced graphene oxide sensor	9
Zirconium phosphate nanoplatelets promote osteogenic differentiation via MAPK/AKT pathway activation in MC3T3-E1 cells	9
Tumor Homing Peptides as Fusion Partners of Therapeutic Proteins for Efficient Delivery to Cancer Cells	9

Adsorption of Lithium on Cell Surface as Nanoparticles through Lithium Binding Peptide Display in Recombinant Escherichia coli	9
Development of Orthogonal Aminoacyl tRNA Synthetase Mutant with Enhanced Incorporation Ability with Para-azido-L-phenylalanine	8
Efficient biodegradation of low-density polyethylene by Pseudomonas plecoglossicida SYp2123 was observed through FT-IR and FE-SEM analysis	8
Development, physico-chemical characterization, and in vivo stability of a novel aglycosylated monoclonal antibody targeting FAM19A5	8
An ultrasound–negative pressure cavitation adsorption method for the recovery of paclitaxel from cell-free culture supernatants of Taxus chinensis	8
Engineering of the Substrate Pocket of α-ketoglutaric Semialdehyde Dehydrogenase for Improving the Activity toward 3-hydroxypropanal	8
Evaluation of Pretreatment and GABA Production Using Levilactobacillus brevis Fermentation of the Seaweed Saccharina japonica	8
Schisandrae Fructus Ameliorates Topical Particulate Matter 2.5-induced Keratoconjunctivitis Sicca That Are Accompanied by Retinal and Lipid Metabolism Disorders	8
Self-assembled micellization of nanoparticles for tunable functionalization by phospholipid-polyethylene glycol	8
Co-utilization of Maltose and Sodium Acetate via Engineered Corynebacterium glutamicum for Improved Itaconic Acid Production	8
Protective effect of Korean Citrus limon pulp ethanol extract on ultraviolet B-induced senescent keratinocytes	8
Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway	8
Metabolic modeling of microorganisms involved in anaerobic digestion	8
Alpha-tocopherol-incorporating liposomes as efficient protectors from skin cell damages by single infrared-A irradiation with cold stress	8
Methane Based Continuous Culture of Methylosinus trichosporium for Production of Poly-3-hydroxybutyrate Using Membrane Recycle System	8
In vitro and in silico study on glucosylation of caprylyl glycol	8
Quantitative analysis of GFP-fused elastin-like polypeptide expression: effects of guest residues, codon sequences, and length	7
Engineering potyvirus-like particles to display multiple copies of tuberculosis antigens	7
High-Throughput Production of Microcapsules for Human Bone Marrow Derived Mesenchymal Stem Cell Biomanufacturing in a Vertical-Wheel Bioreactor	7
Strategies to Enhance the Biosynthesis of Monounsaturated Fatty Acids in Escherichia coli	7
Tuning the Assembly of Bispecific Antibodies by Playing on Differential Polypeptide Chain Molar Ratios	7
Metabolic Engineering of Bacillus megaterium for the Production of β-alanine	7
From gene to green product: an integrated pipeline of biotechnology and green chemistry for sustainable phytochemical production	7
Bioactive Peptides and Its Alternative Processes: A Review	7
Antioxidant and Anticancer Effects of Epsilon-Poly-L-lysine Produced by Two Novel Strains of Paenibacillus polymyxa HS6 and Stenotrophomonas maltophilia YS8	7
Efficient isoprenol production in Escherichia coli via acetyl-CoA redirection	7
Isolation and characterization of two halophilic bacteria producing polyhydroxybutyrate from high-salt environment	7
Reprogramming of Saccharomyces cerevisiae for sustainable cis, cis-muconic acid production from lignocellulosic biomass	7
Hyaluronic Acid Stimulated Enterocytic Differentiation of Intestinal Stem Cells and Enhanced Enteroid Grafting on Scaffolds	7
Transcriptional Characterization of the Effects of Macrophages on Inflammation-Induced Reconstructed Human Skin Equivalents	7
Ginkgolide B Suppresses TPA-induced Metastatic Potential in MCF-7 Human Breast Cancer Cells by Inhibiting MAPK/AP-1 Signaling	7
An Overview on Wound Dressings and Sutures Fabricated by Electrospinning	7
Enhanced 2,3-butanediol recovery from fermentation broth: a study on isobutanol/sodium chloride aqueous two-phase systems	7
Production of chitosan from Aspergillus niger and quantitative evaluation of the process using adapted analytical tools	6
Quantitative Methods for Metabolite Analysis in Metabolic Engineering	6
An integrated in silico reverse vaccinology approach for multi-epitope vaccine designing against Shigellosis caused by Shigella flexneri serotype X	6
An Algicidal Agent against Harmful Algae Using Novel N1-benzyl-N3, N3-diethylpropane-1,3-diamine Derivatives	6
Enhanced cytotoxicity of natural killer cells with Zn-alginate hydrogel microspheres	6
Stability Enhancement of Target Enzymes via Tyrosinase-Mediated Site-Specific Polysaccharide Coating	6
In silico screening and validation of different dehydrogenases to produce 2,3-butanediol in Bacillus subtilis	6
Colorimetric detection of milk spoilage at low temperatures: a novel PDA/ZnO@NC membrane for pH-based freshness monitoring	6
Curcumin Stimulates UCP1-independent Thermogenesis in 3T3-L1 White Adipocytes but Suppresses in C2C12 Muscle Cells	6
Large-scale direct sensing of pine trees for diagnosing pine wilt disease	6
Preparation and characterization of tannase immobilized titanium dioxide nanoparticles	6
Highly selective strategy for the extraction with salting-out method of bio 1,5-pentanediol produced from Escherichia coli whole-cell reaction	6
Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine	6
Optimization of enzymatic extraction of astaxanthin from Xanthophyllomyces dendrorhous using a recombinant cellulase	6
ATP1A2 negatively regulates myogenic differentiation and thermogenesis in C2C12 myoblasts	6
Advancing biofoundry development: strategies and challenges	6
Enhanced production of scopolamine and atropine alkaloids in in vitro cell suspension cultures of Atropa belladonna L. under 2-iP, 2,4-D, and ornithine	6
Inhibitory functions of Veratramine on high mobility group box protein 1-mediated severe inflammatory responses	6
Chrysin stimulates UCP1-independent thermogenesis in 3T3-L1 adipocytes and mouse model	5
Inhibitory Activities of GDX-365 on HMGB1-mediated Septic Responses	5
1-Deoxynojirimycin-producing bacteria: production, optimization, biosynthesis, biological activities	5
CRISPR/Cas12a-mediated electrochemical biosensor for the sensitive detection of Vibrio parahaemolyticus	5
Intracellular cholesterol efflux effects of mannose-beta cyclodextrin conjugates on cholesterol-laden foam cells	5
Biomimetic systems from microalgae and cyanobacteria: applications in biosensing, microrobots, engineered living materials and three-dimensional bioprinting	5
Oligopeptides derived from rice protein hydrolysates: absorption, bioactivity, preparation, debittering, and application	5
Theabrownin in Black Tea Suppresses UVB-induced Matrix Metalloproteinase-1 Expression in HaCaT Keratinocytes	5
Development of Tat-fused drug binding protein to improve anti-cancer effect of mammalian target of rapamycin inhibitors	5
Study on a Low-temperature Cellulose-degrading Strain: Fermentation Optimization, Straw Degradation, and the Effect of Fermentation Broth on Seed Growth	5
Y-shaped oligonucleotides: a promising platform for enhanced therapy with siRNA and CpG Oligodeoxyribonucleotides	5
Tn5 transposase: a key tool to decrypt random transposition	5
Near-infrared and Thermo-sensitive Liposomes Incorporating Thiolated-carboxymethyl Cellulose-capped Gold Nanoparticles and Poly(N-isopropylacrylamide)	5
Development of a Spacer-optimized Quenchbody against Tumor Necrosis Factor Alpha	5
Characterization of GabT1, Yktc1, and GutB1 of Bacillus velezensis K26 and analysis of enzymatic one-pot reaction	5
Event-specific loop-mediated isothermal amplification for living modified cotton MON88701, MON531, MON15985, MON88913, and COT102	5
ROSA26 BAC-based system enables continuous high-yield protein production	5
Immobilization study of a monomeric oleate hydratase from Rhodococcus erythropolis	5
Recent advancements in flavonoid production through engineering microbial systems	5
Investigating the Performance of Machine Learning Methods in Predicting Functional Properties of the Hydrogenase Variants	5
Engineering of Escherichia coli intracellular metabolism by introduction of protein scaffold for the efficient production of 1-propanol	5
Reconstruction of genome-scale metabolic models of non-conventional yeasts: current state, challenges, and perspectives	5
Optimization of Vacuum Frying Process for Sweet Potato Chip Manufacturing Using Response Surface Methodology and Artificial Neural Network Model	5
Omics and CRISPR in CHO bioproduction: a state-of-the-art review	5
Circ_0005280 Protects Human Lens Epithelial Cells against H2O2-induced Apoptosis and Oxidative Stress though miR-326/PLCD3 Axis	5
Memristor device based on bioengineered elastin-like polypeptide and its bionanohybrid	5
An efficient method for isolation and expansion of hematopoietic stem cells derived from human umbilical cord blood cells	5
Preparation of 3-hydroxy propionic acid from levulinic acid by using Baeyer–Villiger monooxygenase as a key enzyme	4
Improvement of Lipid and Terpenoid Yield in Thraustochytrids Using Chemical Regulators: A Review	4

Highly regenerable waste sawdust-derived acidic catalysts for multiple-cycle biodiesel production from waste cooking oil	4
Hypertonic and vibrational modification of K562 feeder cells enhances natural killer cell activation	4
A neural ordinary differential equation model for predicting the growth of Chinese Hamster Ovary cell in a bioreactor system	4
Poly(ε-caprolactone), zinc oxide nanoparticles, and chitosan scaffold as skin substitutes: mechanical strength and cell viability analysis	4
A Cell-free Protein Synthesis Method for the Detection of Heavy Metal Ions Using a Personal Glucose Meter	4
High cell density cultivation of Methylorubrum extorquens using a modified pH-stat supplemented with intermittent formate feeding	4
Physicochemical Characteristics and Biogas Production Potentials of Olive Flounder and Starry Flounder Wastes	4
Rational modification of Tn5 transposase insertion bias via in silico modeling and in vivo assay	4
One-step spheroid formation via double-emulsion drops generated by a glass capillary-based microfluidic device for circadian rhythm investigation	4
Optimization of Process Parameters for Enhanced Production of Ranibizumab in Escherichia coli	4
Natural products ameliorating the adverse health effects by air particulate matter	4
Development of funnel-type fluidized bed reactor system using microcarriers for cultures of adherent cells	4
Safe and efficient treatment of drug-resistant colorectal cancer cells using kaempferol-loaded exosomes	4
Hydrolyzed oyster extracts suppress lipopolysaccharide-mediated inflammation and oxidative stress in RAW264.7 murine macrophages	4
Elucidation of the Role of Gas Bubbles in the Fractional Precipitation of Paclitaxel	4
Nanoemulsion as an Effective Inhibitor of Biofilm-forming Bacterial Associated Drug Resistance: An Insight into COVID Based Nosocomial Infections	4
Natural/Synthetic Polymer Materials for Bioink Development	4
Early short-term hypoxia exposure potentiates anti-tumor activity of natural killer cells	4
Chaperone-assisted chromatography oxidative refolding of disulfide-rich hyaluronidase from inclusion bodies	4
MiR-466d Targeting MMP13 Promotes the Differentiation of Osteoblasts Exposed to a Static Magnetic Field	4
Integrating genomic and ex vivo drug sensitivity profiling to predict treatment outcomes in Korean patients with non-Hodgkin lymphoma	4
Self-assembled Nanocomplex Using Cellulose Nanocrystal Based on Zinc/DNA Nanocluster for Gene Delivery	4
Virus-like Particles as Antiviral Vaccine: Mechanism, Design, and Application	4
Anisotropic alignment and mechanical properties of chitin nanofibers in marine hydroid perisarc	3
Enzymatic synthesis of nylon precursors by 4-aminobutyrate aminotransferase and 6-oxohexanoate dehydrogenase	3
Pan-genome Analysis Reveals Comparative Genomic Features of Central Metabolic Pathways in Methylorubrum extorquens	3
Degradation of 1,4-dioxane by Newly Isolated Acinetobacter sp. M21 with Molasses as the Auxiliary Substrate	3
Erratum to: Utilization of Glucocorticoids as Additives for Enhanced Sialylation of Fc-fusion Protein in CHO Cell Cultures	3
Harnessing balloon flower root-derived nanovesicles to mitigate hyperglycemia-induced cellular senescence	3
Quantitative Label-free Determination of Thrombin Using a Chemically-modified M13 Virus-electrode Interface	3
Retraction Note to: An alternative high-throughput staining method for detection of neutral lipids in green microalgae for biodiesel applications	3
A deep learning framework for HbA1c levels assessment using short-term continuous glucose monitoring data	3
RNA scaffold-guided assembly of lycopene biosynthetic enzymes CrtE, CrtB, and CrtI for in vitro lycopene synthesis	3
Highly Porous and Rigid, Full-thickness Human Skin Model from the Slime-webbed Fiber Scaffold	3
Use of endogenous acetate kinase for ATP regeneration system of whole-cell L-theanine production catalyzed by γ-glutamylmethylamide synthetase	3
Exploration of novel salt-tolerant β-galactosidases for GOS synthesis based on whole genome sequencing of Bacillus hwajinpoensis Zjut HJ2101	3
Hsa_circ_0001165 Regulates the Malignant Phenotype and Angiogenesis of Prostate Cancer Cells through miR-654-3p/DDAH1	3
Mechanical Stretch Promotes Invasion of Lung Cancer Cells via Activation of Tumor Necrosis Factor-alpha	3
Cell-free supernatant-assisted biogenic silver nanoparticles enhance the antibacterial efficacy of communicating bacterial pathogens	3
Real-time, Economical Identification of Microplastics Using Impedance-based Interdigital Array Microelectrodes and k-Nearest Neighbor Model	3
Changes in Fungal Community and Gene Expression of Specific Ligninolytic Enzymes in Response to Wood Decay	3
Comprehensive study on the inhibition mechanism of alpha-glucosidase by flavonoids via kinetic and structural analysis	3
Calculation of All Possible Stoichiometric Coefficients and Theoretical Yields of Microbial Global Reactions	3
Improvement of Sleeping Beauty Transposon System Enabling Efficient and Stable Protein Production	3
Bioactivity assay of Endophytes Colletotrichum siamense strain 67 and Meyerozyma guilliermondii strain CBS 2077 isolated from Stevia rebaudiana (Bertoni) Bertoni and their stevioside glycoside product	3
Rapid and scalable purification of Escherichia coli active ribosomes using strong anion exchange spin columns	3
Xylose Fermentation Was Improved by Kluyveromyces marxianus KHM89 through Up-regulation of Nicotinamide Adenine Dinucleotide (NAD+) Salvage Pathway	3
Biocatalytic syn-stereoselective synthesis of alkyloxime, oxime ether, and their derivatives	3
Biofoundries: Bridging Automation and Biomanufacturing in Synthetic Biology	3