OOIR: Observatory of International Research

Papers

(The TQCC of Korean Journal of Physiology & Pharmacology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
IDH2 gene deficiency accelerates unilateral ureteral obstruction-induced kidney inflammation through oxidative stress and activation of macrophages	27
Mad2B forms a complex with Cdc20, Cdc27, Rev3 and Rev1 in response to cisplatin-induced DNA damage	14
Deletion of adipose triglyceride lipase abolishes blood flow increase after β3-adrenergic stimulation in visceral adipose tissue of mice	13
Carbon monoxide activation of delayed rectifier potassium currents of human cardiac fibroblasts through diverse pathways	13
A simple and novel equation to estimate the degree of bleeding in haemorrhagic shock: mathematical derivation and preliminary in vivo validation	13
Corrigendum to: Pre-ischemic treatment with ampicillin reduces neuronal damage in the mouse hippocampus and neostriatum after transient forebrain ischemia	12
Protective effects and mechanism of coenzyme Q10 and vitamin C on doxorubicin-induced gastric mucosal injury and effects of intestinal flora	11
Carvacrol improves blood lipid and glucose in rats with type 2 diabetes mellitus by regulating short-chain fatty acids and the GPR41/43 pathway	10
Wogonin attenuates vascular remodeling by inhibiting smooth muscle cell proliferation and migration in hypertensive rat	10
Naringenin modulates GABA mediated response in a sexdependent manner in substantia gelatinosa neurons of trigeminal subnucleus caudalis in immature mice	10
Effects of sleep deprivation on coronary heart disease	10
Unveiling the impact of lysosomal ion channels: balancing ion signaling and disease pathogenesis	9
Ca²⁺ entry through reverse Na+/Ca²⁺ exchanger in NCI-H716, glucagon-like peptide-1 secreting cells	9
Aurantio-obtusin exerts an anti-inflammatory effect on acute kidney injury by inhibiting NF-κB pathway	9
HMGB1 increases RAGE expression in vascular smooth muscle cells via ERK and p-38 MAPK-dependent pathways	9
27-Hydroxycholesterol induces macrophage gene expression via LXR-dependent and -independent mechanisms	9
Lyso-globotriaosylsphingosine induces endothelial dysfunction via autophagy-dependent regulation of necroptosis	8
Hyperbaric oxygenation applied before or after mild or hard stress: effects on the redox state in the muscle tissue	8
MST1R as a potential new target antigen of chimeric antigen receptor T cells to treat solid tumors	8
Characterization of a conjugated polysuccinimide-carboplatin compound	8
Low-frequency auricular vagus nerve stimulation facilitates cerebrospinal fluid influx by promoting vasomotion	8
The NADPH oxidase inhibitor diphenyleneiodonium suppresses Ca²⁺ signaling and contraction in rat cardiac myocytes	8
3,3′,4,4′-tetrachlorobiphenyl (PCB77) enhances human Kv1.3 channel currents and alters cytokine production	7
Role of TGF-β1/SMADs signalling pathway in resveratrol-induced reduction of extracellular matrix deposition by dexamethasone-treated human trabecular meshwork cells	7
Lactobacillus johnsonii JERA01 upregulates the production of Th1 cytokines and modulates dendritic cells-mediated immune response	7

Neogambogic acid relieves myocardial injury induced by sepsis via p38 MAPK/NF-κB pathway	7
Transcriptional regulation of genetic variants in the SLC40A1 promoter	6
Specific kinesin and dynein molecules participate in the unconventional protein secretion of transmembrane proteins	6
Lithium and exercise ameliorate insulin-deficient hyperglycemia by independently attenuating pancreatic α-cell mass and hepatic gluconeogenesis	6
Construction and validation of a synthetic phage-displayed nanobody library	6
Hemin attenuates bleomycin-induced lung fibrosis in mice by regulating the TGF-β1/MAPK and AMPK/SIRT1/PGC-1α/HO-1/NF-κB pathways	6
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling	6
The impact of CYP2D6 on donepezil concentration and its lack of effect on the treatment response and adverse effect in Korean patients with Alzheimer’s disease	6
Development and assessment of nano drug delivery systems for combined delivery of rosuvastatin and ezetimibe	6
Gaseous signal molecule SO₂ regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes	6
Biophysically stressed vascular smooth muscle cells express MCP-1 via a PDGFR-β-HMGB1 signaling pathway	6
GBA inhibition suppresses ovarian cancer growth, survival and receptor tyrosine kinase AXL-mediated signaling pathways	6
Microglial galectin-3 increases with aging in the mouse hippocampus	6
Nicotinamide phosphoribosyltransferase regulates the cell differentiation and mineralization in cultured odontoblasts	5
Inhibitory effects of the atypical antipsychotic, clozapine, on voltage-dependent K⁺ channels in rabbit coronary arterial smooth muscle cells	5
Melittin inhibits MPP⁺-induced HT22 cell death by suppressing Bax activation and improving mitochondrial function	5
Dexmedetomidine alleviates blood-brain barrier disruption in rats after cerebral ischemia-reperfusion by suppressing JNK and p38 MAPK signaling	5
Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling pathway	5
Functional interplay between non-canonical inflammasomes and autophagy in inflammatory responses and diseases	5
Mechanism of Wenshen Xuanbi Decoction in the treatment of osteoarthritis based on network pharmacology and experimental verification	5
Store-operated calcium entry in the satellite glial cells of rat sympathetic ganglia	5
Rosuvastatin activates autophagy via inhibition of the Akt/mTOR axis in vascular smooth muscle cells	5
Whole body hypoxic preconditioning-mediated multiorgan protection in db/db mice via nitric oxide-BDNF-GSK-3β-Nrf2 signaling pathway	4
Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase	4
Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner	4
Effects of gas signaling molecule SO₂ in cardiac functions of hyperthyroid rats	4
Lysophosphatidylcholine induces azurophil granule translocationviaRho/Rho kinase/F-actin polymerization in human neutrophils	4
Gallic acid-mitochondria targeting sequence-H₃R₉ induces mitochondria-targeted cytoprotection	4
Decrease of glycogen synthase kinase 3β phosphorylation in the rat nucleus accumbens shell is necessary for amphetamineinduced conditioned locomotor activity	4
Corrigendum to: Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion	4
Neurosteroids and neurological disorders	4
Vinpocetine, a phosphodiesterase 1 inhibitor, mitigates atopic dermatitis-like skin inflammation	4
Beneficial effects of naringenin and morin on interleukin-5 and reactive oxygen species production in BALB/c mice with ovalbumin-induced asthma	4
Triptolide improves myocardial fibrosis in rats through inhibition of nuclear factor kappa B and NLR family pyrin domain containing 3 inflammasome pathway	4
MicroRNA-21 promotes epithelial-mesenchymal transition and migration of human bronchial epithelial cells by targeting poly (ADP-ribose) polymerase-1 and activating PI3K/AKT signaling	3
Carbon monoxide activates large-conductance calcium-activated potassium channels of human cardiac fibroblasts through various mechanisms	3
Docetaxel-loaded PLGA nanoparticles to increase pharmacological sensitivity in MDA-MB-231 and MCF-7 breast cancer cells	3
Brain energy homeostasis: the evolution of the astrocyte-neuron lactate shuttle hypothesis	3
Atypical antipsychotic drug olanzapine inhibits 5-HT₃ receptor-mediated currents by allosteric and non-competitive mechanisms	3
Requirement of β subunit for the reduced voltage-gated Na⁺ current of a Brugada syndrome patient having novel double missense mutation (p.A385T/R504T) of SCN5A	3
Association between metabolic syndrome components and cardiac autonomic modulation in southern Indian adults with pre-metabolic syndrome: hyperglycemia is the major contributing factor	3
Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway	3
Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway	3
Differential expression of ORAI channels and STIM proteins in renal cell carcinoma subtypes: implications for metastasis and therapeutic targeting	3
Antioxidation and anti-inflammatory effects of gamma-irradiated silk sericin and fibroin in H2O2-induced HaCaT Cell	3
Apoptin gene delivery by a PAMAM dendrimer modified with a nuclear localization signal peptide as a gene carrier for brain cancer therapy	3
Carnosol induces the osteogenic differentiation of bone marrow-derived mesenchymal stem cells via activating BMP-signaling pathway	3
Loss of RAR-α and RXR-α and enhanced caspase-3-dependent apoptosis in N-acetyl-p-aminophenol-induced liver injury in mice is tissue factor dependent	3
Oxytocin-induced endothelial nitric oxide dependent vasorelaxation and ERK1/2-mediated vasoconstriction in the rat aorta	3
Astragalus polysaccharide ameliorates diabetic retinopathy by inhibiting the SHH-Gli1-AQP1 signaling pathway in streptozotocin-induced type 2 diabetic rats	3

Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation