OOIR: Observatory of International Research

Papers

(The TQCC of Experimental and Molecular Medicine is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-12-01 to 2024-12-01.)

Article	Citations
The mechanism of HMGB1 secretion and release	370
Zebrafish as an animal model for biomedical research	254
Type I and III interferon responses in SARS-CoV-2 infection	215
On the origin and evolution of SARS-CoV-2	198
Stress and the dopaminergic reward system	193
Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury	182
Hepatocellular carcinoma: old friends and new tricks	180
Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission	165
Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms	160
The aftermath of the interplay between the endoplasmic reticulum stress response and redox signaling	153
Innate immune sensing of coronavirus and viral evasion strategies	153
Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis	149
Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators	147
Protein arginine methyltransferases: promising targets for cancer therapy	135
Tailoring photosensitive ROS for advanced photodynamic therapy	132
The evolution and future of influenza pandemic preparedness	122
Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis	121
Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions	119
Function of γδ T cells in tumor immunology and their application to cancer therapy	117
Severe fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy	115
Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance	112
LSD1: more than demethylation of histone lysine residues	104
METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner	94
Nuciferine modulates the gut microbiota and prevents obesity in high-fat diet-fed rats	81
The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders	78

Roles of circadian clocks in cancer pathogenesis and treatment	76
Aurora kinase A, a synthetic lethal target for precision cancer medicine	73
O-GlcNAcylation in health and neurodegenerative diseases	71
Tumor microenvironment and radioresistance	69
Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway	67
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability	66
Gut microbiota restoration through fecal microbiota transplantation: a new atopic dermatitis therapy	63
Organoids in image-based phenotypic chemical screens	62
Mitochondrial quality control in intervertebral disc degeneration	59
Tumor-promoting macrophages prevail in malignant ascites of advanced gastric cancer	58
Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice	57
Transcriptional regulatory network for the establishment of CD8+ T cell exhaustion	54
Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis	52
Regulation of common neurological disorders by gut microbial metabolites	52
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion	51
Senescent tumor cells: an overlooked adversary in the battle against cancer	50
Interactions between tumor-derived proteins and Toll-like receptors	50
Immunomodulatory functional foods and their molecular mechanisms	48
m6A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis	46
Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis	45
Organoids as host models for infection biology – a review of methods	45
Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease	44
Regulation of antiviral innate immune signaling and viral evasion following viral genome sensing	42
Neuroendocrine control of appetite and metabolism	39
S100A9 in adult asthmatic patients: a biomarker for neutrophilic asthma	39
GSK3B induces autophagy by phosphorylating ULK1	37