Experimental and Molecular Medicine

Papers
(The median citation count of Experimental and Molecular Medicine is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Exploiting the mechanism of estrogen-induced transcription to fight breast cancer396
Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss268
BIX01294 inhibits EGFR signaling in EGFR-mutant lung adenocarcinoma cells through a BCKDHA-mediated reduction in the EGFR level215
Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals198
LINC00319 promotes cancer stem cell-like properties in laryngeal squamous cell carcinoma via E2F1-mediated upregulation of HMGB3182
Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy170
Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response168
Calbindin regulates Kv4.1 trafficking and excitability in dentate granule cells via CaMKII-dependent phosphorylation159
Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations in mismatch repair genes in methotrexate-resistant HT-29 cells157
Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis153
TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury147
Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis135
SRF is a nonhistone methylation target of KDM2B and SET7 in the regulation of skeletal muscle differentiation132
Methods in organoids: a model that goes beyond our imagination122
Novel KCNQ4 variants in different functional domains confer genotype- and mechanism-based therapeutics in patients with nonsyndromic hearing loss122
Hypothalamic primary cilium: A hub for metabolic homeostasis119
Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis117
Relapse of pathological angiogenesis: functional role of the basement membrane and potential treatment strategies115
Protein arginine methyltransferases: promising targets for cancer therapy78
Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells76
MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-473
The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis71
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability69
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway66
Fibrinolytic nanocages dissolve clots in the tumor microenvironment, improving the distribution and therapeutic efficacy of anticancer drugs66
Roles of circadian clocks in cancer pathogenesis and treatment64
Plasma extracellular vesicle delivery of miR-210-3p by targeting ATG7 to promote sepsis-induced acute lung injury by regulating autophagy and activating inflammation62
Aurora kinase A, a synthetic lethal target for precision cancer medicine54
Neuroendocrine control of appetite and metabolism52
The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders52
Type I and III interferon responses in SARS-CoV-2 infection52
Proto-oncoprotein Zbtb7c and SIRT1 repression: implications in high-fat diet-induced and age-dependent obesity51
Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair48
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells46
ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP145
The clinical use of blood-test factors for Alzheimer’s disease: improving the prediction of cerebral amyloid deposition by the QPLEXTM Alz plus assay kit45
circSPG21 protects against intervertebral disc disease by targeting miR-1197/ATP1B344
Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis42
The p53-caspase-2 axis in the cell cycle and DNA damage response42
Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-β1 pathways in IVF embryos39
MicroRNA-26a/b-5p promotes myocardial infarction-induced cell death by downregulating cytochrome c oxidase 5a39
Improved resolution in single-molecule localization microscopy using QD-PAINT37
Glutathione peroxidase-1 regulates ASK1-dependent apoptosis via interaction with TRAF2 in RIPK3-negative cancer cells36
Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia35
Splenectomy improves liver fibrosis via tumor necrosis factor superfamily 14 (LIGHT) through the JNK/TGF-β1 signaling pathway34
The impact of fine particulate matter (PM) on various beneficial functions of human endometrial stem cells through its key regulator SERPINB234
PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis34
Application of QPLEXTM biomarkers in cognitively normal individuals across a broad age range and diverse regions with cerebral amyloid deposition34
LncRNA HSPA7 in human atherosclerotic plaques sponges miR-223 and promotes the proinflammatory vascular smooth muscle cell transition33
REDD1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregulation of VEGFR-2/3 expression32
Gastrointestinal cancer organoids—applications in basic and translational cancer research32
Emerging and re-emerging fatal viral diseases32
Function of γδ T cells in tumor immunology and their application to cancer therapy32
On the origin and evolution of SARS-CoV-230
Organoids as host models for infection biology – a review of methods29
Organoids in image-based phenotypic chemical screens28
Editorial Expression of Concern: Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species producti28
CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury28
Hippocampal regenerative medicine: neurogenic implications for addiction and mental disorders27
WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling26
Inducible Prmt1 ablation in adult vascular smooth muscle leads to contractile dysfunction and aortic dissection26
GSK3B induces autophagy by phosphorylating ULK126
The interplay of microRNAs and transcription factors in autophagy regulation in nonalcoholic fatty liver disease26
Tumor microenvironment and radioresistance25
Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury25
Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer25
Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa25
Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency22
IL-30† (IL-27A): a familiar stranger in immunity, inflammation, and cancer22
Concept and application of circulating proteasomes22
Ahnak deficiency attenuates high-fat diet-induced fatty liver in mice through FGF21 induction21
Hepatocyte organoids and cell transplantation: What the future holds21
Regulation of MDM2 E3 ligase-dependent vascular calcification by MSX1/220
Loss of Sirt6 in adipocytes impairs the ability of adipose tissue to adapt to intermittent fasting20
Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis20
Gut microbiota restoration through fecal microbiota transplantation: a new atopic dermatitis therapy20
Excessive mechanical strain accelerates intervertebral disc degeneration by disrupting intrinsic circadian rhythm20
The role of exosomal lncRNAs in cancer biology and clinical management19
Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP19
Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease19
From bedside to bench: regulation of host factors in SARS-CoV-2 infection18
The evolution and future of influenza pandemic preparedness18
Roles of IκB kinases and TANK-binding kinase 1 in hepatic lipid metabolism and nonalcoholic fatty liver disease18
Retraction Note: Downregulation of the long noncoding RNA MBNL1-AS1 protects sevoflurane-pretreated mice against ischemia-reperfusion injury by targeting KCNMA118
Cereblon contributes to the development of pulmonary fibrosis via inactivation of adenosine monophosphate-activated protein kinase α118
Mutational spectrum of SARS-CoV-2 during the global pandemic18
The roles of the inhibitory autophagy regulator Rubicon in the heart: A new therapeutic target to prevent cardiac cell death18
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