OOIR: Observatory of International Research

Papers

(The H4-Index of Experimental and Molecular Medicine is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway	554
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability	223
Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis	184
Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-β1 pathways in IVF embryos	109
Melatonin and doxorubicin synergistically enhance apoptosis via autophagy-dependent reduction of AMPKα1 transcription in human breast cancer cells	101
Inducible Prmt1 ablation in adult vascular smooth muscle leads to contractile dysfunction and aortic dissection	83
Loss of Sirt6 in adipocytes impairs the ability of adipose tissue to adapt to intermittent fasting	81
Dissecting single-cell genomes through the clonal organoid technique	79
Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP	79
An unusual nicotinamide derivative, 4-pyridone-3-carboxamide ribonucleoside (4PYR), is a novel endothelial toxin and oncometabolite	77
Roles of IκB kinases and TANK-binding kinase 1 in hepatic lipid metabolism and nonalcoholic fatty liver disease	74
O-GlcNAcylation in health and neurodegenerative diseases	72
Single-cell analysis of salt-induced hypertensive mouse aortae reveals cellular heterogeneity and state changes	69
Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli	67
Fecal microbiota transplantation ameliorates atherosclerosis in mice with C1q/TNF-related protein 9 genetic deficiency	66
Thrap3 promotes R-loop resolution via interaction with methylated DDX5	56
CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury	55
Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency	51
Tie1 contributes to the development of ovarian hyperstimulation syndrome under the regulation of EGR1 in granulosa cells	46
Senescent tumor cells: an overlooked adversary in the battle against cancer	45
The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats	45
Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions	42
Human kidney organoids reveal the role of glutathione in Fabry disease	42
Single-cell transcriptome analysis reveals cellular heterogeneity in the ascending aortas of normal and high-fat diet-fed mice	42
Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia	41

TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury	41
ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1	40
Concept and application of circulating proteasomes	39
Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis	39
Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair	39
Hepatocyte organoids and cell transplantation: What the future holds	32
Excessive mechanical strain accelerates intervertebral disc degeneration by disrupting intrinsic circadian rhythm	31
Oncogenic E3 ubiquitin ligase NEDD4 binds to KLF8 and regulates the microRNA-132/NRF2 axis in bladder cancer	31