OOIR: Observatory of International Research

Papers

(The H4-Index of Experimental and Molecular Medicine is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
The mechanism of HMGB1 secretion and release	330
Zebrafish as an animal model for biomedical research	235
Type I and III interferon responses in SARS-CoV-2 infection	210
On the origin and evolution of SARS-CoV-2	198
Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury	182
Hepatocellular carcinoma: old friends and new tricks	180
The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies	176
Stress and the dopaminergic reward system	175
Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms	156
Innate immune sensing of coronavirus and viral evasion strategies	153
Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission	151
The aftermath of the interplay between the endoplasmic reticulum stress response and redox signaling	144
Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis	137
Protein arginine methyltransferases: promising targets for cancer therapy	135
Tailoring photosensitive ROS for advanced photodynamic therapy	132
Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators	129
Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis	115
Severe fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy	115
Function of γδ T cells in tumor immunology and their application to cancer therapy	114
The evolution and future of influenza pandemic preparedness	111
Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions	110
Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance	109
LSD1: more than demethylation of histone lysine residues	104
Single-cell network biology for resolving cellular heterogeneity in human diseases	90
METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner	90

DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells	84
Nuciferine modulates the gut microbiota and prevents obesity in high-fat diet-fed rats	81
Small but mighty: the causes and consequences of micronucleus rupture	81
Cancer-associated fibroblast-secreted exosomal miR-423-5p promotes chemotherapy resistance in prostate cancer by targeting GREM2 through the TGF-β signaling pathway	77
Roles of circadian clocks in cancer pathogenesis and treatment	73
O-GlcNAcylation in health and neurodegenerative diseases	71
Tumor microenvironment and radioresistance	69
The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders	69
Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway	67
Aurora kinase A, a synthetic lethal target for precision cancer medicine	65
Mitochondrial quality control in intervertebral disc degeneration	59
Gut microbiota restoration through fecal microbiota transplantation: a new atopic dermatitis therapy	58
Tumor-promoting macrophages prevail in malignant ascites of advanced gastric cancer	58
Organoids in image-based phenotypic chemical screens	57
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability	57
Transcriptional regulatory network for the establishment of CD8+ T cell exhaustion	54
Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis	52
Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice	52
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion	51
Advances in transcriptome analysis of human brain aging	51
Interactions between tumor-derived proteins and Toll-like receptors	50
Senescent tumor cells: an overlooked adversary in the battle against cancer	50
Regulation of common neurological disorders by gut microbial metabolites	49