Oncotargets and Therapy

Papers
(The TQCC of Oncotargets and Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Cancer and the Vasopressin Gene: Radioimmunoassay Values and Commentary on Copeptin as a Plasma Marker58
Sustained Clinical Response to 4th-Line Therapy with Selpercatinib in RET Fusion-Positive Combined Small Cell Lung Cancer45
Identification of an m7G-Related lncRNA Signature for Prognostic Prediction and Immune Landscape Characterization in Early Gastric Cancer39
Long Non-Coding RNA LINC01089 Enhances the Development of Gastric Cancer by Sponging miR-145-5p to Mediate SOX9 Expression [Retraction]36
MicroRNA-211 Promotes Non-Small-Cell Lung Cancer Proliferation and Invasion by Targeting MxA [Retraction]33
Effects of Combined Inhibition of STAT3 and VEGFR2 Pathways on the Radiosensitivity of Non-Small-Cell Lung Cancer Cells [Retraction]33
Anti-Tumor Effects of Gilteritinib on FLT3 Mutations: Insights into Resistance Mechanisms in Ba/F3 Cell Models28
Exploring Protein Expression Profiles in Lung Cancer Insufficient Microwave Ablation: Implications for Recurrence26
Efficacy and Safety of Regorafenib with or without Immune Checkpoint Inhibitors as Second-Line Treatment for Advanced Hepatocellular Carcinoma: A Systematic Review and Arm-Level Synthesis of Real-Worl25
Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer25
Studying Immunogenic Cell Death in Human Colorectal Cancer Organoids24
Ketoacidosis in a Patient with Type 2 Diabetes Requiring Alpelisib: Learnings and Observations Regarding Alpelisib Initiation and Rechallenge21
The Landscape of PARP Inhibitors in Solid Cancers21
miR-141-3p is a Key Negative Regulator of the EGFR Pathway in Osteosarcoma [Retraction]21
Hepatoid Adenocarcinoma of the Lung: Beyond a Shadow of Doubt and Risk of High Mortality [Letter]21
Recurrent Glioblastoma: Ongoing Clinical Challenges and Future Prospects20
LINC00565 Enhances Proliferative Ability in Endometrial Carcinoma by Downregulating KLF9 [Retraction]19
MicroRNA-188-5p Promotes Epithelial–Mesenchymal Transition by Targeting ID4 Through Wnt/β-Catenin Signaling in Retinoblastoma [Retraction]19
MiR-155-5p Accelerates the Metastasis of Cervical Cancer Cell via Targeting TP53INP1 [Retraction]19
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors19
Prognostic Value of Pretreatment Carcinoembryonic Antigen (CEA) in Rectal Cancer Treated with Preoperative Short-Course Radiotherapy with Delayed Surgery or Long-Course Radiotherapy18
LOXL 2 Promotes the Epithelial–Mesenchymal Transition and Malignant Progression of Cervical Cancer [Retraction]18
Successful Retreatment with Crizotinib After Crizotinib-Induced Liver Failure in ALK-Positive Advanced Lung Adenocarcinoma: A Case Report17
Targeting ANXA4 to Overcome Cisplatin Resistance in Ovarian Cancer: A Bioinformatics and in Vitro Study17
Combination of Aumolertinib, Dabrafenib, and Trametinib for a Patient with Advanced Lung Adenocarcinoma with an Osimertinib-Induced BRAF V600E Mutation: A Case Report17
Exploring TGF-β Signaling in Cancer Progression: Prospects and Therapeutic Strategies17
Survival Outcomes in Lung Cancer Patients Newly Diagnosed Through Brain Metastasis Surgery: Impact of Druggable Mutations and Radiotherapy16
Post-Hematopoietic Cell Transplantation Relapsed Acute Lymphoblastic Leukemia: Current Challenges and Future Directions16
Snake Venom Causes Apoptosis by Increasing the Reactive Oxygen Species in Colorectal and Breast Cancer Cell Lines [Corrigendum]16
Efficacy and Safety of the MDM2–p53 Antagonist Brigimadlin (BI 907828) in Patients with Advanced Biliary Tract Cancer: A Case Series16
Hsp90 Inhibitor NMS-E973 Exerts the Anticancer Effect Against Glioblastoma via Induction of PUMA-Mediated Apoptosis [Retraction]15
A Review of SIK2 in Ovarian Cancer: Function and Emerging Targeted Therapies15
Evaluating the Prognostic Value of a Pan-Cancer Circulating Tumor DNA Next-Generation Sequencing Panel in Advanced Cancer Patients15
Pan-Cancer Analysis of WRN: From Multi-Omics Biomarker Discovery to Therapy-Guiding Functional Evidence15
CD93: A Promising NETs-Related Biomarker for Diagnosis and Therapy in Actinic Keratosis15
Identification of Cuproptosis-Related Genes for Molecular Subtyping: Predicting Prognostic and Therapeutic Response in Glioma14
Doxorubicin and Edelfosine Combo-Loaded Lipid–Polymer Hybrid Nanoparticles for Synergistic Anticancer Effect Against Drug-Resistant Osteosarcoma [Retraction]14
Identification of Osteosarcoma Metastasis-Associated Gene Biomarkers and Potentially Targeted Drugs Based on Bioinformatic and Experimental Analysis [Retraction]14
PLK1 Contributes to Autophagy by Regulating MYC Stabilization in Osteosarcoma Cells [Retraction]13
Molecular Characteristics and the Effect of KRAS Mutation on the Prognosis of Immunotherapy in Non-Small Cell Lung Cancer in Xinjiang, China13
Identification of Potential Biomarkers in Papillary Thyroid Carcinoma Based on Proteomics12
Survival Outcomes and Prognostic Factors in Patients with Metastatic Colorectal Cancer Treated First-Line mFOLFOXIRI Plus Bevacizumab: A Real-World Study in Vietnam12
Clinical Applications of Aneuploidies in Evolution of NSCLC Patients: Current Status and Application Prospect12
Knockdown of Immature Colon Carcinoma Transcript-1 Inhibits Proliferation of Glioblastoma Multiforme Cells through Gap 2/Mitotic Phase Arrest [Retraction]12
Precision Nanomedicine for Cancer: Innovations, Strategies, and Translational Challenges12
Hyperbilirubinemia in a Patient Receiving Alectinib for Anaplastic Lymphoma Kinase Positive Non-Small-Cell Lung Cancer: A Histological Features11
Applications of Yttrium-90 (90Y) in Hepatocellular Carcinoma11
Advances in ORMDL Research in Malignant Tumors: A Review11
The Potential Treatment Options and Combination Strategies of KRAS-Mutated Lung Cancer11
Colon Metastasis from Pancreatic Cancer: A Case Report11
The Roles of Serum CXCL16 in Circulating Tregs and Gastrointestinal Stromal Tumor Cells [Retraction]11
Screening and Studying of Blood miRNAs as Potential Diagnostic Markers for Papillary Thyroid Carcinoma11
From Co-Stimulation to Co-Inhibition: A Continuum of Immunotherapy Care Toward Long-Term Survival in Melanoma10
Partial Response to Crizotinib in a Lung Adenocarcinoma Patient with a Novel FBXO11 (Intergenic)-ALK (Exon 20-29) Fusion10
Molecular Changes in Chronic Myeloid Leukemia During Tyrosine Kinase Inhibitors Treatment. Focus on Immunological Pathways10
c-Kit Receptors as a Therapeutic Target in Cancer: Current Insights10
Nephrotoxicity in Bispecific Antibodies Recipients: Focus on T-Cell-Engaging Bispecific Antibodies10
Noncoding RNA-Mediated High Expression of PFKFB3 Correlates with Poor Prognosis and Tumor Immune Infiltration of Lung Adenocarcinoma9
Targeting the Inactive Conformation of the Epidermal Growth Factor Receptor Identifies EG31: A Novel Small Molecule Inhibitor Effective Against Normal and 5-Fluorouracil-Resistant Triple Negative Brea9
HER2-Directed Therapy in Advanced Breast Cancer: Benefits and Risks9
Elevated Expression of Tiam1 Is Associated with Poor Prognosis and Promotes Tumor Progression in Pancreatic Cancer [Retraction]9
LOXL1-AS1 Drives the Progression of Gastric Cancer via Regulating miR-142-5p/PIK3CA Axis [Retraction]9
Vitamin C Selectively Inhibits Kidney Renal Clear Cell Carcinoma Cell Growth by Suppressing the HIF-1 Pathway9
A Circular RNA Derived from Golgi Glycoprotein 1 mRNA Regulates KRAS Expression and Promotes Colorectal Cancer Progression by Targeting microRNA-622 [Retraction]9
Comprehensive Pan-Cancer Analysis of the Prognostic Role of KLF Transcription Factor 2 (KLF2) in Human Tumors9
MFAP2 Promotes Epithelial–Mesenchymal Transition in Gastric Cancer Cells by Activating TGF-β/SMAD2/3 Signaling Pathway [Retraction]9
Small Nucleolar RNAs (snoRNAs) in Cancer: From Biogenesis to Clinical Potential8
Scalp Metastasis After Breast Cancer Surgery: A Case Report8
Concentrations of Irinotecan and SN-38 in the Ascites and the Fluid Product of Cell-Free and Concentrated Ascites Reinfusion Therapy 9 Days After Administration of Irinotecan in a Patient with Gastric8
Management and Future Therapeutic Perspectives of Classic Kaposi’s Sarcoma: An Evidence-Based Review8
Oral Anlotinib Maintenance Therapy for an Advanced Malignant Peritoneal Mesothelioma Diagnosed by Laparoscopy After Initial Misdiagnosis to Obtain Longer Progression-Free Survival: Case Report and Lit8
Cetuximab and Dabrafenib Plus Trametinib for Untreated Colonic Metastasis of BRAFV600E Mutant Primary Lung Adenocarcinoma with Signet Ring Cell Features: An Interesting and Rare Case Report8
Curcumin Potentiates the Potent Antitumor Activity of ACNU Against Glioblastoma by Suppressing the PI3K/AKT and NF-κB/COX-2 Signaling Pathways [Retraction]8
UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1 [Retraction]7
CRISPR-Cas13a Targeting the FGFR3-TACC3 Fusion Gene Inhibits Proliferation of Bladder Cancer Cells in vitro and in vivo7
Synchronous Multiple Primary Malignant Adenocarcinoma of the Descending Colon and Fungating Bleeding Adenocarcinoma of the Terminal Ileum Presenting Massive Rectal Bleeding: A Trap for the Unwary7
MicroRNA 628 Suppresses Migration and Invasion of Breast Cancer Stem Cells through Targeting SOS1 [Retraction]7
A Nomogram Prognostic Model for Advanced Hepatocellular Carcinoma Based on the Interaction Between CD8+T Cell Counts and Age7
Down-Regulation of SREBP via PI3K/AKT/mTOR Pathway Inhibits the Proliferation and Invasion of Non-Small-Cell Lung Cancer Cells [Retraction]7
A Novel Intergenic Region (chr2: 30,316,870)-ALK Fusion in a Patient with Lung Adenocarcinoma Responding to Crizotinib Combined with Pemetrexed Treatment: A Case Report7
Hopea odorata Extract Inhibits Hepatocellular Carcinoma via Induction of Caspase-Dependent Apoptosis [Erratum]7
ALK-Positive Anaplastic Large-Cell Lymphoma in a Patient with Chronic Lymphocytic Leukemia: A Case Report and Literature Review7
Implications of the Receptor Tyrosine Kinase Axl in Gastric Cancer Progression [Retraction]7
A Durable Response of Primary Advanced Colonic Plasmacytoma Using a Combination of Surgical Resection and Adjuvant Bortezomib: A Case Report and Literature Review7
Antimetastatic Effect of Epigenetic Drugs, Hydralazine and Valproic Acid, in Ras-Transformed NIH 3T3 Cells [Corrigendum]7
Targeting of KDM5A by miR-421 in Human Ovarian Cancer Suppresses the Progression of Ovarian Cancer Cells [Retraction]7
Liquid-Based Cytology of Small Cell Carcinoma of the Cervix: A Multicenter Retrospective Study7
PAX8 as a Potential Target for Ovarian Cancer: What We Know so Far7
Long Noncoding RNA SNHG15 Serves as an Oncogene and Predicts Poor Prognosis in Epithelial Ovarian Cancer [Retraction]6
Real-World Experience of Niraparib as Maintenance Therapy in Patients with Newly Diagnosed Advanced Ovarian Cancer: A Single-Center Retrospective Study6
Tumor-Homing Antibody-Cytokine Fusions for Cancer Therapy6
The Potential Role and Effective Components of Sanyeqing as the Potential Therapeutic Candidates for IBD and CRC6
Efficacy and Safety of Combined PD-1 Inhibitor With Induction Chemotherapy Followed by IMRT Plus Nimotuzumab in Locally Advanced Nasopharyngeal Carcinoma: A Retrospective Analysis6
miR-218 Overexpression Suppresses Tumorigenesis of Papillary Thyroid Cancer via Inactivation of PTEN /PI3K/AKT Pathway by Targeting Runx2 [Retraction]6
Prognostic Value of miR-10a-3p in Non-Small Cell Lung Cancer Patients6
Traditional Chinese Medicine in Cushing’s Syndrome: A Narrative Review of Pathophysiology and Potential Therapeutic Effects6
Cervical Lymphadenopathy as Initial Presentation of Foamy Gland Adenocarcinoma of the Prostate: A Case Report6
Systemic Treatment for Gynecological Cancer Patients Undergoing Hemodialysis6
Targeted Treatment of Adults with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL): Tafasitamab in Context6
Upregulated Ubiquitin D is a Favorable Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative Concurrent Chemoradiotherapy6
Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression [Retraction]6
High BCR::ABL1 Expression Defines CD34+ Cells with Significant Alterations in Signal Transduction, Short-Proliferative Potential and Self-Renewal Ability6
miR-495 Inhibits Proliferation, Migration, and Invasion and Induces Apoptosis via Inhibiting PBX3 in Melanoma Cells [Retraction]6
Prognostic Impact of Pre-Treatment CRP/Albumin Ratio in Patients with Advanced-Stage Epithelial Ovarian Cancer6
Serum Response Factor Expression, Microvascular Density, and Postoperative Recurrence in Glioblastoma6
β-Catenin Promotes Cell Proliferation, Migration, and Invasion but Induces Apoptosis in Renal Cell Carcinoma [Retraction]6
A Multidisciplinary Approach to Improve the Management of Immune-Checkpoint Inhibitor-Related Pneumonitis5
MicroRNA-212 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induces Apoptosis by Targeting FOXA1 [Retraction]5
Cytotoxic Evaluation, Molecular Docking, Molecular Dynamics, and ADMET Prediction of Isolupalbigenin Isolated from Erythrina subumbrans (Hassk). Merr. (Fabaceae) Stem Bark: Unveiling Its Anticancer Ef5
The Study of PIK3CA Hotspot Mutations and Co-Occurring with EGFR, KRAS, and TP53 Mutations in Non-Small Cell Lung Cancer5
RPL38 Regulates the Proliferation and Apoptosis of Gastric Cancer via miR-374b-5p/VEGF Signal Pathway [Retraction]5
Mechanism of microRNA-152-3p-Mediated Regulation of Autophagy and Sensitivity in Paclitaxel-Resistant Ovarian Cancer Cells5
Capmatinib in MET Exon 14 Skipping Mutation-Positive Lung Adenocarcinoma with Extensive Central Nervous System Metastasis5
FMS-Like Tyrosine Kinase 3 Inhibitors in the Treatment of Acute Myeloid Leukemia: An Update on the Emerging Evidence and Safety Profile5
CCDC7 Activates Interleukin-6 and Vascular Endothelial Growth Factor to Promote Proliferation via the JAK-STAT3 Pathway in Cervical Cancer Cells [Retraction]5
Ectopic Adrenocorticotropic Hormone-Secreting Pituitary Adenoma in the Clivus Region: A Case Report5
Current Evidence and Future Perspectives about the Role of PARP Inhibitors in the Treatment of Thoracic Cancers5
Roles of SPOCK1 in the Formation Mechanisms and Treatment of Non-Small-Cell Lung Cancer and Brain Metastases from Lung Cancer5
Let-7c-5p Inhibits Cell Proliferation and Migration and Promotes Apoptosis via the CTHRC1/AKT/ERK Pathway in Esophageal Squamous Cell Carcinoma [Retraction]5
Antitumor Effect of Triptolide in T-Cell Lymphoblastic Lymphoma by Inhibiting Cell Viability, Invasion, and Epithelial–Mesenchymal Transition via Regulating the PI3K/AKT/mTOR Pathway [Retraction]5
Immune-Checkpoint Inhibitors in Lung Neuroendocrine Tumors – A Systematic Review and Meta-Analysis5
RAB43 Promotes Gastric Cancer Cell Proliferation and Metastasis via Regulating the PI3K/AKT Signaling Pathway [Retraction]5
Familial Acute Promyelocytic Leukemia: A Case Report and Review of the Literature4
Circular RNA Controls Tumor Occurrence and Development via Cell Cycle Regulation4
Extensive-Stage Small-Cell Lung Cancer: Current Landscape and Future Prospects4
Immunotherapy Plus Radiotherapy for the Treatment of Sarcomas: Is There a Potential for Synergism?4
Thyroid Gland as a Metastatic Site for Hepatocellular Carcinoma: A Rare Case Report4
HOXC Cluster Antisense RNA 3, a Novel Long Non-Coding RNA as an Oncological Biomarker and Therapeutic Target in Human Malignancies4
KDM5C Expedites Lung Cancer Growth and Metastasis Through Epigenetic Regulation of MicroRNA-133a [Retraction]4
Response to Article “Serum Levels of Galectin-9 are Increased in Cervical Cancer Patients and are Higher in Advanced Clinical Stages” [Response to Letter]4
Prolonged Clinical Benefit with Futibatinib in a Patient with FGFR Inhibitor–Pretreated FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma: Case Report4
A Comprehensive Review of Advances in Molecular Mechanisms and Targeted Therapies for the Specific Type of Cystic Lung Cancer4
Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung Cancer [Retraction]4
Combination Use of First-Line Afatinib and Proton-Pump Inhibitors Reduces Overall Survival Among Patients with EGFFR Mutant Lung Cancer4
Red Sea Sponge Callyspongia siphonella Extract Induced Growth Inhibition and Apoptosis in Breast MCF-7 and Hepatic HepG-2 Cancer Cell Lines in 2D and 3D Cell Cultures4
Efficacy and Safety of Pyrotinib in Human Epidermal Growth Factor Receptor 2-Positive Advanced Breast Cancer: A Multicenter, Retrospective, Real-World Study4
Primary Hepatic Epithelioid Gastrointestinal Stromal Tumor: A Rare Case4
Management of Regorafenib-Induced Hand-Foot Skin Reaction with Topical Chinese Medicine and Urea Ointment: A Case Report and Literature Review4
The Role of CELMoD Agents in Multiple Myeloma4
SIM2: Its Prognostic Significance and Oncogenic Role in Endometrial Carcinoma4
Diagnosis and Management of Colorectal Cancer in the Gulf Area: Current Practice and Future Suggestions from Expert Opinions4
PTEN Expression Was Significantly Associated with PD-L1 Score but Not with EBV Infection in Gastric Cancer4
Development of a Prognostic Risk Model for Esophageal Cancer Based on M0 Macrophage-Related Genes4
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