Oncotargets and Therapy

Papers
(The TQCC of Oncotargets and Therapy is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Exploring Protein Expression Profiles in Lung Cancer Insufficient Microwave Ablation: Implications for Recurrence66
MicroRNA-211 Promotes Non-Small-Cell Lung Cancer Proliferation and Invasion by Targeting MxA [Retraction]52
Effects of Combined Inhibition of STAT3 and VEGFR2 Pathways on the Radiosensitivity of Non-Small-Cell Lung Cancer Cells [Retraction]42
Cancer and the Vasopressin Gene: Radioimmunoassay Values and Commentary on Copeptin as a Plasma Marker35
Studying Immunogenic Cell Death in Human Colorectal Cancer Organoids31
Progress of Immune Checkpoint Inhibitors Therapy for pMMR/MSS Metastatic Colorectal Cancer31
Case Report: Targeted Therapy with Anlotinib for a Rare Case of Spinal Cord Glioblastoma with FGFR3 Mutation30
Clinical and Pathological Features of Primary Renal Well-Differentiated Neuroendocrine Tumor30
miR-132 Can Inhibit Glioma Cells Invasion and Migration by Target MMP16 in vitro [Retraction]28
LncRNA RNF144A-AS1 Promotes Bladder Cancer Progression via RNF144A-AS1/miR-455-5p/SOX11 Axis [Retraction]26
Sustained Clinical Response to 4th-Line Therapy with Selpercatinib in RET Fusion-Positive Combined Small Cell Lung Cancer25
Overexpressed Long Noncoding RNA TUG1 Affects the Cell Cycle, Proliferation, and Apoptosis of Pancreatic Cancer Partly Through Suppressing RND3 and MT2A [Retraction]23
Long Non-Coding RNA LINC01089 Enhances the Development of Gastric Cancer by Sponging miR-145-5p to Mediate SOX9 Expression [Retraction]22
An Innovative Site-Specific Anti-HER2 Antibody-Drug Conjugate with High Homogeneity and Improved Therapeutic Index22
The Landscape of PARP Inhibitors in Solid Cancers22
Efficient Everolimus Treatment for Metastatic Castration Resistant Prostate Cancer with AKT1 Mutation: A Case Report21
Anti-Tumor Effects of Gilteritinib on FLT3 Mutations: Insights into Resistance Mechanisms in Ba/F3 Cell Models21
A Hybrid Glioma Tumor Cell Lysate Immunotherapy Vaccine Demonstrates Good Clinical Efficacy in the Rat Model [Corrigendum]21
LINC00565 Enhances Proliferative Ability in Endometrial Carcinoma by Downregulating KLF9 [Retraction]20
Hepatoid Adenocarcinoma of the Lung: Beyond a Shadow of Doubt and Risk of High Mortality [Letter]20
MicroRNA-188-5p Promotes Epithelial–Mesenchymal Transition by Targeting ID4 Through Wnt/β-Catenin Signaling in Retinoblastoma [Retraction]19
Ketoacidosis in a Patient with Type 2 Diabetes Requiring Alpelisib: Learnings and Observations Regarding Alpelisib Initiation and Rechallenge19
miR-141-3p is a Key Negative Regulator of the EGFR Pathway in Osteosarcoma [Retraction]19
Prognostic Value of Pretreatment Carcinoembryonic Antigen (CEA) in Rectal Cancer Treated with Preoperative Short-Course Radiotherapy with Delayed Surgery or Long-Course Radiotherapy19
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors18
FGFR2-ERC1: A Subtype of FGFR2 Oncogenic Fusion Variant in Lung Adenocarcinoma and the Response to Anlotinib18
Exploring the Role of Transglutaminase in Patients with Glioblastoma: Current Perspectives17
Progression-Free Survival of a Patient with Advanced Hepatocellular Carcinoma Treated with Adoptive Cell Therapy Using Natural Killer Cells: A Case Report17
Combination of Aumolertinib, Dabrafenib, and Trametinib for a Patient with Advanced Lung Adenocarcinoma with an Osimertinib-Induced BRAF V600E Mutation: A Case Report16
Exploring TGF-β Signaling in Cancer Progression: Prospects and Therapeutic Strategies16
Recurrent Glioblastoma: Ongoing Clinical Challenges and Future Prospects16
Successful Retreatment with Crizotinib After Crizotinib-Induced Liver Failure in ALK-Positive Advanced Lung Adenocarcinoma: A Case Report15
SPINDOC is Highly Expressed in Pan-Cancer Samples and Can Promote the Proliferation, Invasion and Migration of Hepatocellular Carcinoma Cells by Activating Wnt/β-Catenin Signaling Pathway15
AATF is Overexpressed in Human Head and Neck Squamous Cell Carcinoma and Regulates STAT3/Survivin Signaling15
Identification of Osteosarcoma Metastasis-Associated Gene Biomarkers and Potentially Targeted Drugs Based on Bioinformatic and Experimental Analysis [Retraction]15
Snake Venom Causes Apoptosis by Increasing the Reactive Oxygen Species in Colorectal and Breast Cancer Cell Lines [Corrigendum]15
Efficacy and Safety of the MDM2–p53 Antagonist Brigimadlin (BI 907828) in Patients with Advanced Biliary Tract Cancer: A Case Series15
Survival Outcomes in Lung Cancer Patients Newly Diagnosed Through Brain Metastasis Surgery: Impact of Druggable Mutations and Radiotherapy15
Bone Marrow Mesenchymal Stem Cells-Derived Exosomal miR-425-5p Inhibits Acute Myeloid Leukemia Cell Proliferation, Apoptosis, Invasion and Migration by Targeting WTAP [Retraction]15
Precision Nanomedicine for Cancer: Innovations, Strategies, and Translational Challenges14
Molecular Characteristics and the Effect of KRAS Mutation on the Prognosis of Immunotherapy in Non-Small Cell Lung Cancer in Xinjiang, China13
Hsp90 Inhibitor NMS-E973 Exerts the Anticancer Effect Against Glioblastoma via Induction of PUMA-Mediated Apoptosis [Retraction]13
CD93: A Promising NETs-Related Biomarker for Diagnosis and Therapy in Actinic Keratosis13
Identification of Cuproptosis-Related Genes for Molecular Subtyping: Predicting Prognostic and Therapeutic Response in Glioma13
High Red Cell Distribution Width Independently Predicts Adverse Survival in Patients with Newly Diagnosed Skull Base Chordoma12
Screening and Studying of Blood miRNAs as Potential Diagnostic Markers for Papillary Thyroid Carcinoma12
Cytochrome 4Z1 Expression is Associated with Poor Prognosis in Colon Cancer Patients12
Treatment Patterns and Outcomes Among Elderly Glioblastoma Patients in Riyadh, Saudi Arabia12
Selinexor, Bortezomib and Dexamethasone: An Effective Salvage Regimen for Heavily Pretreated Myeloma Patients12
Post-Hematopoietic Cell Transplantation Relapsed Acute Lymphoblastic Leukemia: Current Challenges and Future Directions12
Evaluating the Prognostic Value of a Pan-Cancer Circulating Tumor DNA Next-Generation Sequencing Panel in Advanced Cancer Patients12
Migfilin: Cell Adhesion Effect and Comorbidities12
Efficacy and Drug Resistance Analysis of ALK Inhibitors in Combination with Stereotactic Body Radiation Therapy for Treating Lung Squamous Carcinoma Patient Harboring EML4-ALK Rearrangement11
The Roles of Serum CXCL16 in Circulating Tregs and Gastrointestinal Stromal Tumor Cells [Retraction]11
From Co-Stimulation to Co-Inhibition: A Continuum of Immunotherapy Care Toward Long-Term Survival in Melanoma11
Knockdown of Immature Colon Carcinoma Transcript-1 Inhibits Proliferation of Glioblastoma Multiforme Cells through Gap 2/Mitotic Phase Arrest [Retraction]11
Partial Response to Crizotinib in a Lung Adenocarcinoma Patient with a Novel FBXO11 (Intergenic)-ALK (Exon 20-29) Fusion11
Advances in ORMDL Research in Malignant Tumors: A Review11
Identification of Potential Biomarkers in Papillary Thyroid Carcinoma Based on Proteomics10
Applications of Yttrium-90 (90Y) in Hepatocellular Carcinoma10
Hyperbilirubinemia in a Patient Receiving Alectinib for Anaplastic Lymphoma Kinase Positive Non-Small-Cell Lung Cancer: A Histological Features10
Clinical Evaluation of Ramucirumab for the Treatment of Hepatocellular Carcinoma (HCC): Place in Therapy10
Clinical Applications of Aneuploidies in Evolution of NSCLC Patients: Current Status and Application Prospect10
The Potential Treatment Options and Combination Strategies of KRAS-Mutated Lung Cancer10
The Development of Non-Invasive Diagnostic Tools in Bladder Cancer10
Nephrotoxicity in Bispecific Antibodies Recipients: Focus on T-Cell-Engaging Bispecific Antibodies10
c-Kit Receptors as a Therapeutic Target in Cancer: Current Insights9
Role of Reactivating Mutant p53 Protein in Suppressing Growth and Metastasis of Triple-Negative Breast Cancer9
Noncoding RNA-Mediated High Expression of PFKFB3 Correlates with Poor Prognosis and Tumor Immune Infiltration of Lung Adenocarcinoma9
Colon Metastasis from Pancreatic Cancer: A Case Report9
LOXL1-AS1 Drives the Progression of Gastric Cancer via Regulating miR-142-5p/PIK3CA Axis [Retraction]9
A Novel Intergenic Region (chr2: 30,316,870)-ALK Fusion in a Patient with Lung Adenocarcinoma Responding to Crizotinib Combined with Pemetrexed Treatment: A Case Report8
Management and Future Therapeutic Perspectives of Classic Kaposi’s Sarcoma: An Evidence-Based Review8
Vitamin C Selectively Inhibits Kidney Renal Clear Cell Carcinoma Cell Growth by Suppressing the HIF-1 Pathway8
Targeting the Inactive Conformation of the Epidermal Growth Factor Receptor Identifies EG31: A Novel Small Molecule Inhibitor Effective Against Normal and 5-Fluorouracil-Resistant Triple Negative Brea8
Leptomeningeal Metastatic L858R EGFR-mutant Lung Cancer: Prompt Response to Osimertinib in the Absence of T790M-mutation and Effective Subsequent Pulsed Erlotinib8
Cetuximab and Dabrafenib Plus Trametinib for Untreated Colonic Metastasis of BRAFV600E Mutant Primary Lung Adenocarcinoma with Signet Ring Cell Features: An Interesting and Rare Case Report8
Scalp Metastasis After Breast Cancer Surgery: A Case Report8
Comprehensive Pan-Cancer Analysis of the Prognostic Role of KLF Transcription Factor 2 (KLF2) in Human Tumors8
Molecular Changes in Chronic Myeloid Leukemia During Tyrosine Kinase Inhibitors Treatment. Focus on Immunological Pathways8
Concentrations of Irinotecan and SN-38 in the Ascites and the Fluid Product of Cell-Free and Concentrated Ascites Reinfusion Therapy 9 Days After Administration of Irinotecan in a Patient with Gastric8
Knockdown of Fibrous Sheath Interacting Protein 1 Expression Reduces Bladder Urothelial Carcinoma Cell Proliferation and Induces Apoptosis via Inhibition of the PI3K/AKT Pathway [Retraction]8
HER2-Directed Therapy in Advanced Breast Cancer: Benefits and Risks8
Oral Anlotinib Maintenance Therapy for an Advanced Malignant Peritoneal Mesothelioma Diagnosed by Laparoscopy After Initial Misdiagnosis to Obtain Longer Progression-Free Survival: Case Report and Lit7
Curcumin Potentiates the Potent Antitumor Activity of ACNU Against Glioblastoma by Suppressing the PI3K/AKT and NF-κB/COX-2 Signaling Pathways [Retraction]7
PAX8 as a Potential Target for Ovarian Cancer: What We Know so Far7
Synchronous Multiple Primary Malignant Adenocarcinoma of the Descending Colon and Fungating Bleeding Adenocarcinoma of the Terminal Ileum Presenting Massive Rectal Bleeding: A Trap for the Unwary7
Silencing circZFR Inhibits the Proliferation, Migration and Invasion of Human Renal Carcinoma Cells by Regulating miR-206 [Retraction]7
Liquid-Based Cytology of Small Cell Carcinoma of the Cervix: A Multicenter Retrospective Study7
A Nomogram Prognostic Model for Advanced Hepatocellular Carcinoma Based on the Interaction Between CD8+T Cell Counts and Age7
Targeting TP53-Mutated Acute Myeloid Leukemia: Research and Clinical Developments7
CBX7, a Potential Prognostic Biomarker in Lung Adenocarcinoma7
Long Noncoding RNA SNHG15 Serves as an Oncogene and Predicts Poor Prognosis in Epithelial Ovarian Cancer [Retraction]7
UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1 [Retraction]7
A Durable Response of Primary Advanced Colonic Plasmacytoma Using a Combination of Surgical Resection and Adjuvant Bortezomib: A Case Report and Literature Review7
Down-Regulation of SREBP via PI3K/AKT/mTOR Pathway Inhibits the Proliferation and Invasion of Non-Small-Cell Lung Cancer Cells [Retraction]7
CRISPR-Cas13a Targeting the FGFR3-TACC3 Fusion Gene Inhibits Proliferation of Bladder Cancer Cells in vitro and in vivo7
Implications of the Receptor Tyrosine Kinase Axl in Gastric Cancer Progression [Retraction]7
Genetic Testing and Immunotherapy for Intracranial Inflammatory Myofibroblastic Tumor: A Case Report6
Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression [Retraction]6
The Potential Role and Effective Components of Sanyeqing as the Potential Therapeutic Candidates for IBD and CRC6
Systemic Treatment for Gynecological Cancer Patients Undergoing Hemodialysis6
Upregulated Ubiquitin D is a Favorable Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative Concurrent Chemoradiotherapy6
Hopea odorata Extract Inhibits Hepatocellular Carcinoma via Induction of Caspase-Dependent Apoptosis [Erratum]6
High BCR::ABL1 Expression Defines CD34+ Cells with Significant Alterations in Signal Transduction, Short-Proliferative Potential and Self-Renewal Ability6
Tumor-Homing Antibody-Cytokine Fusions for Cancer Therapy6
Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation [Corrigendum]6
Targeted Treatment of Adults with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL): Tafasitamab in Context6
Current Evidence and Future Perspectives about the Role of PARP Inhibitors in the Treatment of Thoracic Cancers6
Prognostic Value of miR-10a-3p in Non-Small Cell Lung Cancer Patients6
Targeting of KDM5A by miR-421 in Human Ovarian Cancer Suppresses the Progression of Ovarian Cancer Cells [Retraction]6
ALK-Positive Anaplastic Large-Cell Lymphoma in a Patient with Chronic Lymphocytic Leukemia: A Case Report and Literature Review6
Real-World Experience of Niraparib as Maintenance Therapy in Patients with Newly Diagnosed Advanced Ovarian Cancer: A Single-Center Retrospective Study6
Multiple Primary Lung Tumors of Different Pathological Types Including Squamous Cell Carcinoma, Adenocarcinoma, and Mixed Squamous Cell and Glandular Papilloma: A Case Report6
Gastric H+/K+-ATPase Expression in Normal Laryngeal Tissue and Laryngeal Carcinoma [Corrigendum]6
CDKN3 Overcomes Bladder Cancer Cisplatin Resistance via LDHA-Dependent Glycolysis Reprogramming6
Antimetastatic Effect of Epigenetic Drugs, Hydralazine and Valproic Acid, in Ras-Transformed NIH 3T3 Cells [Corrigendum]6
MicroRNA 628 Suppresses Migration and Invasion of Breast Cancer Stem Cells through Targeting SOS1 [Retraction]6
The Role of CELMoD Agents in Multiple Myeloma5
Serum Response Factor Expression, Microvascular Density, and Postoperative Recurrence in Glioblastoma5
Efficacy and Safety of Combined PD-1 Inhibitor With Induction Chemotherapy Followed by IMRT Plus Nimotuzumab in Locally Advanced Nasopharyngeal Carcinoma: A Retrospective Analysis5
Prolonged Clinical Benefit with Futibatinib in a Patient with FGFR Inhibitor–Pretreated FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma: Case Report5
A Comprehensive Review of Advances in Molecular Mechanisms and Targeted Therapies for the Specific Type of Cystic Lung Cancer5
KDM5C Expedites Lung Cancer Growth and Metastasis Through Epigenetic Regulation of MicroRNA-133a [Retraction]5
Development of a Prognostic Risk Model for Esophageal Cancer Based on M0 Macrophage-Related Genes5
Immune-Checkpoint Inhibitors in Lung Neuroendocrine Tumors – A Systematic Review and Meta-Analysis5
HER2 Amplification in Advanced NSCLC Patients After Progression on EGFR-TKI and Clinical Response to EGFR-TKI Plus Pyrotinib Combination Therapy5
The Study of PIK3CA Hotspot Mutations and Co-Occurring with EGFR, KRAS, and TP53 Mutations in Non-Small Cell Lung Cancer5
Capmatinib in MET Exon 14 Skipping Mutation-Positive Lung Adenocarcinoma with Extensive Central Nervous System Metastasis5
RPL38 Regulates the Proliferation and Apoptosis of Gastric Cancer via miR-374b-5p/VEGF Signal Pathway [Retraction]5
MicroRNA-212 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induces Apoptosis by Targeting FOXA1 [Retraction]5
Expression and Prognostic Value of Glucose Transporter 3 in Diffuse Large B Cell Lymphoma5
Cytotoxic Evaluation, Molecular Docking, Molecular Dynamics, and ADMET Prediction of Isolupalbigenin Isolated from Erythrina subumbrans (Hassk). Merr. (Fabaceae) Stem Bark: Unveiling Its Anticancer Ef5
Research Progress of NK Cells in Glioblastoma Treatment5
Mechanism of microRNA-152-3p-Mediated Regulation of Autophagy and Sensitivity in Paclitaxel-Resistant Ovarian Cancer Cells5
Roles of SPOCK1 in the Formation Mechanisms and Treatment of Non-Small-Cell Lung Cancer and Brain Metastases from Lung Cancer5
FMS-Like Tyrosine Kinase 3 Inhibitors in the Treatment of Acute Myeloid Leukemia: An Update on the Emerging Evidence and Safety Profile5
Let-7c-5p Inhibits Cell Proliferation and Migration and Promotes Apoptosis via the CTHRC1/AKT/ERK Pathway in Esophageal Squamous Cell Carcinoma [Retraction]5
HMGB1/RAGE Axis Mediates the Apoptosis, Invasion, Autophay, and Angiogenesis of the Renal Cell Carcinoma [Corrigendum]5
CCDC7 Activates Interleukin-6 and Vascular Endothelial Growth Factor to Promote Proliferation via the JAK-STAT3 Pathway in Cervical Cancer Cells [Retraction]5
Antitumor Effect of Triptolide in T-Cell Lymphoblastic Lymphoma by Inhibiting Cell Viability, Invasion, and Epithelial–Mesenchymal Transition via Regulating the PI3K/AKT/mTOR Pathway [Retraction]5
Ectopic Adrenocorticotropic Hormone-Secreting Pituitary Adenoma in the Clivus Region: A Case Report5
A Multidisciplinary Approach to Improve the Management of Immune-Checkpoint Inhibitor-Related Pneumonitis5
High Intelectin‐1 Expression Associated with Aggressive Tumor Behavior and Worse Survival in Rectal Cancer5
Extensive-Stage Small-Cell Lung Cancer: Current Landscape and Future Prospects5
Management of Regorafenib-Induced Hand-Foot Skin Reaction with Topical Chinese Medicine and Urea Ointment: A Case Report and Literature Review5
Rapid and Efficient Response to Gilteritinib and Venetoclax-Based Therapy in Two AML Patients with FLT3-ITD Mutation Unresponsive to Venetoclax Plus Azacitidine5
RAB43 Promotes Gastric Cancer Cell Proliferation and Metastasis via Regulating the PI3K/AKT Signaling Pathway [Retraction]5
An Effective Hormonal Therapy for a Patient with Estrogen Receptor 1 (ESR1)-Amplified Metastatic Ovarian Cancer: A Case Report5
lncRNA HAND2-AS1 Regulates Prostate Cancer Cell Growth Through Targeting the miR-106a-5p/RBM24 Axis [Retraction]4
Response to Article “Serum Levels of Galectin-9 are Increased in Cervical Cancer Patients and are Higher in Advanced Clinical Stages” [Response to Letter]4
Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung Cancer [Retraction]4
Undifferentiated Large Cell Carcinoma of the Thymus Associated with Plasma-Cell Type Castleman Disease-Like Reaction: A Case Series4
Circular RNA Controls Tumor Occurrence and Development via Cell Cycle Regulation4
Circular RNA circLRCH3 Inhibits Proliferation, Migration, and Invasion of Colorectal Cancer Cells Through miRNA-223/LPP Axis4
HOXC Cluster Antisense RNA 3, a Novel Long Non-Coding RNA as an Oncological Biomarker and Therapeutic Target in Human Malignancies4
Combination Use of First-Line Afatinib and Proton-Pump Inhibitors Reduces Overall Survival Among Patients with EGFFR Mutant Lung Cancer4
Red Sea Sponge Callyspongia siphonella Extract Induced Growth Inhibition and Apoptosis in Breast MCF-7 and Hepatic HepG-2 Cancer Cell Lines in 2D and 3D Cell Cultures4
Overcoming Obstacles in Liquid Biopsy Developments for Prostate Cancer4
SIM2: Its Prognostic Significance and Oncogenic Role in Endometrial Carcinoma4
PTEN Expression Was Significantly Associated with PD-L1 Score but Not with EBV Infection in Gastric Cancer4
Immunotherapy Plus Radiotherapy for the Treatment of Sarcomas: Is There a Potential for Synergism?4
Circular RNA SMARCA5 Inhibits the Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer by miR-19b-3p/HOXA9 Axis [Retraction]4
Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation [Corrigendum]4
Familial Acute Promyelocytic Leukemia: A Case Report and Review of the Literature4
Thyroid Gland as a Metastatic Site for Hepatocellular Carcinoma: A Rare Case Report4
Efficacy and Safety of Pyrotinib in Human Epidermal Growth Factor Receptor 2-Positive Advanced Breast Cancer: A Multicenter, Retrospective, Real-World Study4
Identification and Validation a Necroptosis‑related Prognostic Signature and Associated Regulatory Axis in Stomach Adenocarcinoma4
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