Molecular Diagnosis & Therapy

Papers
(The median citation count of Molecular Diagnosis & Therapy is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Worldwide Prevalence of Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer: A Meta-Analysis83
Current and Emerging Applications of Droplet Digital PCR in Oncology: An Updated Review52
Lutetium Lu 177 Vipivotide Tetraxetan: First Approval42
Current and Emerging Clinical Treatment in Mitochondrial Disease41
Smelling the Disease: Diagnostic Potential of Breath Analysis41
Inferring Potential CircRNA–Disease Associations via Deep Autoencoder-Based Classification40
MET-Targeted Therapies and Clinical Outcomes: A Systematic Literature Review38
Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression37
Bi-specific and Tri-specific NK Cell Engagers: The New Avenue of Targeted NK Cell Immunotherapy35
Piflufolastat F 18: Diagnostic First Approval35
Clinical Exome Reanalysis: Current Practice and Beyond33
Modern Biomarkers for Autism Spectrum Disorder: Future Directions32
Leveraging the Fragment Length of Circulating Tumour DNA to Improve Molecular Profiling of Solid Tumour Malignancies with Next-Generation Sequencing: A Pathway to Advanced Non-invasive Diagnostics in 27
Achromatopsia: Genetics and Gene Therapy27
IDH Inhibitors and Beyond: The Cornerstone of Targeted Glioma Treatment26
Evaluation of the Suitability of RNAscope as a Technique to Measure Gene Expression in Clinical Diagnostics: A Systematic Review24
Reduction of Off-Target Effects of Gapmer Antisense Oligonucleotides by Oligonucleotide Extension21
Treatable Mechanisms in Asthma20
Commercial ctDNA Assays for Minimal Residual Disease Detection of Solid Tumors20
Analytical and Clinical Performance of Droplet Digital PCR in the Detection and Quantification of SARS-CoV-219
The Ubiquitin Proteasome System and Skin Fibrosis19
Metastasis Prevention: Focus on Metastatic Circulating Tumor Cells19
Elivaldogene Autotemcel: First Approval18
Epigenetics Beyond Fetal Growth Restriction: A Comprehensive Overview18
Epigenetics and ADHD: Reflections on Current Knowledge, Research Priorities and Translational Potential18
A Prospective Evaluation of the Analytical Performance of GENECUBE® HQ SARS-CoV-2 and GENECUBE® FLU A/B17
Circulating Exosomes of Neuronal Origin as Potential Early Biomarkers for Development of Stroke17
Future Prospects for Epigenetics in Autism Spectrum Disorder16
Proteomic Alterations in Salivary Exosomes Derived from Human Papillomavirus-Driven Oropharyngeal Cancer16
Exagamglogene Autotemcel: First Approval16
Concordance Study of a 520-Gene Next-Generation Sequencing-Based Genomic Profiling Assay of Tissue and Plasma Samples15
Omics in Seminal Plasma: An Effective Strategy for Predicting Sperm Retrieval Outcome in Non-obstructive Azoospermia15
Clinical Performance of the cobas Liat SARS-CoV-2 & Influenza A/B Assay in Nasal Samples14
Predictive Value of EGFR-PI3K-AKT-mTOR-Pathway Inhibitor Biomarkers for Head and Neck Squamous Cell Carcinoma: A Systematic Review14
Molecular Diagnosis of Inherited Cardiac Diseases in the Era of Next-Generation Sequencing: A Single Center’s Experience Over 5 Years14
Glioma 2021 WHO Classification: The Superiority of NGS Over IHC in Routine Diagnostics13
Targeting Mutated KRAS Genes to Treat Solid Tumours13
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis12
Diagnostic Accuracy of Two Molecular Tools for Diagnosis of Congenital Chagas Disease12
The lncRNA PRINS-miRNA-mRNA Axis Gene Expression Profile as a Circulating Biomarker Panel in Psoriasis11
Application of Nanopore Sequencing in the Diagnosis and Treatment of Pulmonary Infections11
Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option11
The Genetics of Inflammatory Bowel Disease11
Expansion of the CRISPR/Cas Genome-Sculpting Toolbox: Innovations, Applications and Challenges11
Smad7 Antisense Oligonucleotide-Based Therapy in Crohn's Disease: Is it Time to Re-Evaluate?11
Detecting ALK Rearrangement with RT-PCR: A Reliable Approach Compared with Next-Generation Sequencing in Patients with NSCLC11
Serum Levels of miR-146a in Patients with Psoriasis10
Using RNA-seq to Assess Off-Target Effects of Antisense Oligonucleotides in Human Cell Lines10
The Potential of Nanobodies for COVID-19 Diagnostics and Therapeutics10
Hyperactivating p53 in Human Papillomavirus-Driven Cancers: A Potential Therapeutic Intervention10
Evaluating Infectious, Neoplastic, Immunological, and Degenerative Diseases of the Central Nervous System with Cerebrospinal Fluid-Based Next-Generation Sequencing10
Equecabtagene Autoleucel: First Approval9
Clinical Utility of Implementing a Frontline NGS-Based DNA and RNA Fusion Panel Test for Patients with Suspected Myeloid Malignancies9
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin9
Gestational Diabetes is Associated with an Increased Expression of miR-27a in Peripheral Blood Mononuclear Cells9
Tabelecleucel: First Approval9
Flotufolastat F 18: Diagnostic First Approval9
Immuno-Oncolytic Viruses: Emerging Options in the Treatment of Colorectal Cancer9
Prevalence of NTRK Fusions in Canadian Solid Tumour Cancer Patients9
Emerging Landscape of SARS-CoV-2 Variants and Detection Technologies9
Hepatic Clearance of Cell-Free DNA: Possible Impact on Early Metastasis Diagnosis8
SARS-CoV-2 Testing Strategies in the Diagnosis and Management of COVID-19 Patients in Low-Income Countries: A Scoping Review8
Proclarix, A New Biomarker for the Diagnosis of Clinically Significant Prostate Cancer: A Systematic Review8
Role of Long Intergenic Noncoding RNAs in Cancers with an Overview of MicroRNA Binding8
The Diagnostic Accuracy of miR-371a-3p for Testicular Germ Cell Tumors: A Systematic Review and Meta-Analysis8
Human Papillomavirus DNA Detection by Droplet Digital PCR in Formalin-Fixed Paraffin-Embedded Tumor Tissue from Oropharyngeal Squamous Cell Carcinoma Patients8
The Potential Use of Peripheral Blood Mononuclear Cells as Biomarkers for Treatment Response and Outcome Prediction in Psychiatry: A Systematic Review8
Camelid Single-Domain Antibodies for the Development of Potent Diagnosis Platforms8
Neurofilament Light Chain as a Biomarker in Cerebral Small-Vessel Disease8
A Window of Opportunity for Newborn Screening8
Mutational Characteristics of Primary Mucosal Melanoma: A Systematic Review8
Economic Evaluation of Monoclonal Antibodies in Metastatic Colorectal Cancer: A Systematic Review7
Steps to Improve Precision Medicine in Epilepsy7
Follicular T Helper and Breg Cell Balance in Severe Allergic Asthma Before and After Omalizumab Therapy7
Pitfalls in Cutaneous Melanoma Diagnosis and the Need for New Reliable Markers7
Improved Variant Detection in Clinical Myeloid NGS Testing by Supplementing a Commercial Myeloid NGS Assay with Custom or Extended Data Filtering and Accessory Fragment Analysis7
Functional Association of miR-133b and miR-21 Through Novel Gene Targets ATG5, LRP6 and SGPP1 in Coronary Artery Disease7
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors7
CAH-X Syndrome: Genetic and Clinical Profile7
Oxidative Stress and Potential Antioxidant Therapies in Vitiligo: A Narrative Review7
Effect of E-cadherin on Prognosis of Colorectal Cancer: A Meta-Analysis Update7
Candidate MicroRNA Biomarkers in Lupus Nephritis: A Meta-analysis of Profiling Studies in Kidney, Blood and Urine Samples7
Routine Molecular Screening of Patients with Advanced Non-SmallCell Lung Cancer in Circulating Cell-Free DNA at Diagnosis and During Progression Using OncoBEAMTM EGFR V2 and NGS Technologies6
Molecular Diagnosis of Primary Cardiomyopathy in 231 Unrelated Pediatric Cases by Panel-Based Next-Generation Sequencing: A Major Focus on Five Carriers of Biallelic TNNI3 Pathogenic Variants6
The Road Ahead for Circulating microRNAs in Diagnosis and Management of Testicular Germ Cell Tumors6
Immune-Checkpoint Expression on CD4, CD8 and NK Cells in Blood, Bronchoalveolar Lavage and Lymph Nodes of Sarcoidosis6
Salivary Biomarkers as Indicators of TBI Diagnosis and Prognosis: A Systematic Review6
Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients6
Milestones of Precision Medicine: An Innovative, Multidisciplinary Overview6
RNA Sequencing Data from Human Intracranial Aneurysm Tissue Reveals a Complex Inflammatory Environment Associated with Rupture6
MicroRNAs Function in Dental Stem Cells as a Promising Biomarker and Therapeutic Target for Dental Diseases6
BACs-on-Beads Assay for the Prenatal Diagnosis of Microdeletion and Microduplication Syndromes6
Epidermolysis Bullosa: A Review of the Tissue-Engineered Skin Substitutes Used to Treat Wounds6
System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration6
Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus5
The Value of Pharmacogenetics to Reduce Drug-Related Toxicity in Cancer Patients5
Preimplantation Genetic Testing for Monogenic Conditions: Is Cell-Free DNA Testing the Next Step?5
Optimizing the Diagnostic Strategy to Identify Genetic Abnormalities in Miscarriage5
Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination5
Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis5
Internal Standardization of the Interpretation and Reporting of Sequence Variants in Hematologic Neoplasms5
Progress in Clinical Gene Therapy for Cardiac Disorders5
‘Longing’ for the Next Generation of Liquid Biopsy: The Diagnostic Potential of Long Cell-Free DNA in Oncology and Prenatal Testing5
Nucleic Acid Quality Assessment is Critical to the Success of the Oncomine Dx Target Test for Lung Cancer5
Longitudinal Relationship between Idylla Plasma ctBRAF V600 Mutation Detection and Tumor Burden in Patients with Metastatic Melanoma5
The Opportunities and Challenges of Molecular Tagging Next-Generation Sequencing in Liquid Biopsy5
Profiling of Circulating Gene Expression Reveals Molecular Signatures Associated with Intracranial Aneurysm Rupture Risk5
Associations between HLA-Cw1 and Systemic Treatment Response of Asian Psoriasis Patients4
Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of “Second Hit” in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma4
Celomic Fluid: Laboratory Workflow for Prenatal Diagnosis of Monogenic Diseases4
Digital PCR-Based Method for Detecting CDKN2A Loss in Brain Tumours4
Omidubicel: First Approval4
EasyNAT MP Assay: A Simple, Rapid, and Low-Cost Method to Detect Mycoplasma pneumoniae Using Cross-Priming Amplification Technology4
Long-Read Nanopore Sequencing of RPGR ORF15 is Enhanced Following DNase I Treatment of MinION Flow Cells4
Lifileucel: First Approval4
Biomarkers for Nonexudative Age-Related Macular Degeneration and Relevance for Clinical Trials: A Systematic Review4
Epigenetics in Non-tumor Immune-Mediated Skin Diseases4
Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of Ravulizumab4
Development of an Affordable ELISA Targeting the SARS-CoV-2 Nucleocapsid and Its Application to Samples from the Ongoing COVID-19 Epidemic in Ghana4
Prognostic Biomarker-Based Identification of Drugs for Managing the Treatment of Endometrial Cancer4
Single-Cell Sequencing in Neurodegenerative Disorders4
Clostridium Bacteria: Harnessing Tumour Necrosis for Targeted Gene Delivery3
Lutetium-177 Labelled Anti-PSMA Monoclonal Antibody (Lu-TLX591) Therapy for Metastatic Prostate Cancer: Treatment Toxicity and Outcomes3
Advances in RNA Viral Vector Technology to Reprogram Somatic Cells: The Paramyxovirus Wave3
The Role οf Ion Channels in the Development and Progression of Prostate Cancer3
Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis3
Smart PROTACs Enable Controllable Protein Degradation for Precision Cancer Therapy3
A Review of CRISPR-Based Advances in Dermatological Diseases3
Optimizing CAR-T Therapy for Glioblastoma3
Expression Signature of Immune-Related MicroRNAs in Autoimmune Skin Disease: Psoriasis and Vitiligo Insights3
The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications3
Indirect Clinical Validation of a Programmed Death-Ligand 1 Laboratory-Developed Test for Gastric/Gastroesophageal Junction Adenocarcinoma with 22C3 Antibody Concentrate3
Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders3
Ongoing Challenges in the Diagnosis of 11p15.5-Associated Imprinting Disorders3
Genetic Profiling of Diffuse Large B-Cell Lymphoma: A Comparison Between Double-Expressor Lymphoma and Non-Double-Expressor Lymphoma3
Evaluation of Factors that Affect the Performance of COVID-19 Molecular Assays Including Presence of Symptoms, Number of Detected Genes and RNA Extraction Type3
Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta-Analysis3
Herpes Simplex Virus-1 and -2 Rapid Detection in Whole Blood3
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