Molecular Diagnosis & Therapy

Papers
(The median citation count of Molecular Diagnosis & Therapy is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
ADORA3: A Key Player in the Pathogenesis of Intracranial Aneurysms and a Potential Diagnostic Biomarker142
Predictive Ability of Serum Amino Acid Levels to Differentiate Fibromyalgia Patients from Healthy Subjects94
The Role of MicroRNAs in the Pathogenesis and as Biomarkers for Pediatric Epilepsy: A Systematic Review77
Commercial ctDNA Assays for Minimal Residual Disease Detection of Solid Tumors66
A Window of Opportunity for Newborn Screening65
Indirect Clinical Validation of a Programmed Death-Ligand 1 Laboratory-Developed Test for Gastric/Gastroesophageal Junction Adenocarcinoma with 22C3 Antibody Concentrate51
Molecular Therapy for Choroideremia: Pre-clinical and Clinical Progress to Date49
Comment on “Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta‑Analysis”45
Personalized Cancer Monitoring Assay for the Detection of ctDNA in Patients with Solid Tumors39
Gene Therapy for Cardiomyocyte Renewal: Cell Cycle, a Potential Therapeutic Target37
Evaluation of Minimal Residual Disease in Patients with Neuroblastoma36
FAPI-Targeted Molecular Imaging: Transforming Insights into Post-Ischemic Myocardial Remodeling?36
Expression Signature of Immune-Related MicroRNAs in Autoimmune Skin Disease: Psoriasis and Vitiligo Insights30
Drug Hypersensitivity Reactions in Patients with Cystic Fibrosis: Potential Value of the Lymphocyte Toxicity Assay to Assess Risk29
Prediction of Biomarker Expression on Primary Pancreatic Ductal Adenocarcinoma Tissues Using Fine-Needle Biopsies: Paving the Way for a Patient-Tailored Molecular Imaging Approach27
Research Progress on Signal Conversion Based on Aptamer Combined CRISPR/Cas System in Biosensors27
Advances and Challenges in the Diagnosis of Leishmaniasis25
Glioma 2021 WHO Classification: The Superiority of NGS Over IHC in Routine Diagnostics22
Fatty Acid Desaturase: The Yin or Yang of Disease Pathology22
Inflammatory Gene Panel Guiding the Study of Genetics in Inflammatory Bowel Disease21
Personalizing Oncolytic Immunovirotherapy Approaches21
Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders20
Clinical Metagenomic Next-Generation Sequencing for Diagnosis of Central Nervous System Infections: Advances and Challenges20
Afamitresgene Autoleucel: First Approval19
Correction to: Revakinagene Taroretcel: First Approval18
Transcript-Based Diagnosis and Expanded Phenotype of an Intronic Mutation in TPM3 Myopathy17
Comment on “The Diagnostic and Prognostic Value of miR‑155 in Cancers: An Updated Meta‑analysis”17
Development of a New Rapid Simultaneous Molecular Assay for the Detection of STI Pathogens and Drug Resistance-Associated Mutations16
Long-Range PCR and Nanopore Sequencing Enables High-Throughput Detection of TCF4 Trinucleotide Repeat Expansions in Fuchs Endothelial Corneal Dystrophy16
Current and Emerging Applications of Droplet Digital PCR in Oncology: An Updated Review16
Smart PROTACs Enable Controllable Protein Degradation for Precision Cancer Therapy16
Advances in Pompe Disease Treatment: From Enzyme Replacement to Gene Therapy16
Molecular Therapeutics in Development to Treat Alzheimer’s Disease16
Diagnosis of Lung Cancer Through Exhaled Breath: A Comprehensive Study15
MET-Targeted Therapies and Clinical Outcomes: A Systematic Literature Review15
Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer14
The Road Traveled and Journey Ahead for the Genetics and Genomics of Tinnitus14
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis13
Molecular Dynamics as a Precision Therapy: A Perspective on Epileptic Encephalopathies13
Targeted Therapy in Salivary Gland Cancer: Prevalence of a Selected Panel of Actionable Molecular Alterations in a German Tertiary Referral Center Patient Cohort13
Achromatopsia: Genetics and Gene Therapy13
Performance of a Rapid Digital PCR Test for the Detection of Non-Small Cell Lung Cancer (NSCLC) Variants13
Evolutionary Overview and Future Perspectives: ESR1 Mutations, Liquid Biopsy, and Artificial Intelligence for a New Era of Personalized Medicine in ER+ Breast Cancer12
Preimplantation Genetic Testing for Monogenic Conditions: Is Cell-Free DNA Testing the Next Step?12
Is the Homologous Recombination Repair Mutation Defined by a 15-Gene Panel Associated with the Prognosis of Epithelial Ovarian Cancer?12
In vivo LNP-CRISPR Approaches for the Treatment of Hemophilia12
Correction to: Molecular Therapeutics in Development to Treat Alzheimer’s Disease12
Lifileucel: First Approval11
Celomic Fluid: Laboratory Workflow for Prenatal Diagnosis of Monogenic Diseases11
Selecting Targets for Molecular Imaging of Gastric Cancer: An Immunohistochemical Evaluation11
The Role οf Ion Channels in the Development and Progression of Prostate Cancer11
Role of lncRNAs in Remodeling of the Coronary Artery Plaques in Patients with Atherosclerosis11
Correction: Recent Advancements in Nanomaterials: A Promising Way to Manage Neurodegenerative Disorders11
Comment on “Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta‑Analysis”10
Correction to: Analytical and Clinical Performance of Droplet Digital PCR in the Detection and Quantification of SARS-CoV-210
Cell-Free HPV-DNA in Screening, Diagnosis, Prognosis, and Treatment Response Monitoring of Cervical Cancer10
Bridging the Gap: Cost-Effective Strategies for Detecting Ph-Like B-Lineage ALL in Resource-Limited Settings10
Correction to: Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus10
Fluorescence Imaging-Assessed Surgical Margin Detection in Head and Neck Oncology by Passive and Active Targeting9
Correction to: Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of R9
Extracellular Histones Profiles of Pediatric H3K27-Altered Diffuse Midline Glioma9
Emerging RNAi Therapies to Treat Hypertension9
Psoriasis: A Multidimensional Review of Onset, Progression, Treatment, and the Evolution of Disease Models9
Human Papillomavirus Type and Viral Load in Relation to Circulating Cell-Free Tumour HPV DNA Level and Survival in Cervical Cancer8
Blood Biomarkers of Long COVID: A Systematic Review8
Flavonoids in the Treatment of Non-small Cell Lung Cancer via Immunomodulation: Progress to Date8
Papillary Thyroid Carcinoma: Correlation Between Molecular and Clinical Features8
The Role of [18F]F-FDG PET/CT for Predicting Histology and Prognosis in Patients with Thymic Lesions8
Future Prospects for Epigenetics in Autism Spectrum Disorder8
Obecabtagene Autoleucel: First Approval8
Exploratory Prognostic Biomarkers of Complement-Mediated Thrombotic Microangiopathy (CM-TMA) in Adults with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of a Phase III Study of Ravulizumab8
Chimeric Genes Causing 11β-Hydroxylase Deficiency: Implications in Clinical and Molecular Diagnosis8
Diagnostic Approaches to Investigate JAK2-Unmutated Erythrocytosis Based on a Single Tertiary Center Experience8
Author reply to Wang et al.: “The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta‑analysis”8
Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of “Second Hit” in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma8
Inner Ear Gene Therapy: An Overview from Bench to Bedside8
EasyNAT MP Assay: A Simple, Rapid, and Low-Cost Method to Detect Mycoplasma pneumoniae Using Cross-Priming Amplification Technology8
Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma8
Mutational Characteristics of Primary Mucosal Melanoma: A Systematic Review8
Functional Association of miR-133b and miR-21 Through Novel Gene Targets ATG5, LRP6 and SGPP1 in Coronary Artery Disease7
The Complement System and C4b-Binding Protein: A Focus on the Promise of C4BPα as a Biomarker to Predict Clopidogrel Resistance7
Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta-Analysis7
Nanocarrier-Mediated Delivery of MicroRNAs for Fibrotic Diseases7
Exploring the Role of HtrA Family Genes in Cancer: A Systematic Review7
Cardiovascular Aging: From Molecular Mechanisms to Targeted Therapies7
Evaluation of the Suitability of RNAscope as a Technique to Measure Gene Expression in Clinical Diagnostics: A Systematic Review7
Effective Utilization of a Customized Targeted Hybrid Capture RNA Sequencing in the Routine Molecular Categorization of Adolescent and Adult B-Lineage Acute Lymphoblastic Leukemia: A Real-World Experi7
Identification of Somatic Genetic Variants in Superficial Vascular Malformations by Liquid Biopsy in a Cohort of 88 Patients from a French Hospital6
Long-Read Nanopore Sequencing of RPGR ORF15 is Enhanced Following DNase I Treatment of MinION Flow Cells6
Tumour Marker Expression in Head and Neck Malignancies to Identify Potential Targets for Intraoperative Molecular Near-Infrared Imaging6
‘Longing’ for the Next Generation of Liquid Biopsy: The Diagnostic Potential of Long Cell-Free DNA in Oncology and Prenatal Testing6
Molecular Diagnosis of Primary Cardiomyopathy in 231 Unrelated Pediatric Cases by Panel-Based Next-Generation Sequencing: A Major Focus on Five Carriers of Biallelic TNNI3 Pathogenic Variants6
Optimization of a Quantitative PCR Methodology for Detection of Aspergillus spp. and Rhizopus arrhizus6
Advances in RNA Viral Vector Technology to Reprogram Somatic Cells: The Paramyxovirus Wave6
Is There a Role for FAPI PET in Urological Cancers?6
Zevorcabtagene Autoleucel: First Approval6
Evaluation of Factors that Affect the Performance of COVID-19 Molecular Assays Including Presence of Symptoms, Number of Detected Genes and RNA Extraction Type6
Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies6
The Potential of Nanobodies for COVID-19 Diagnostics and Therapeutics6
Advancing Rabies Diagnosis: Time for a New “Gold Standard”?5
Clonal Hematopoiesis from a Diagnostic Perspective: 10 Years of CHIP5
A miRNA-Based Approach in Autosomal Dominant Polycystic Kidney Disease: Challenges and Insights from Adult to Pediatric Evidence5
Clostridium Bacteria: Harnessing Tumour Necrosis for Targeted Gene Delivery5
Tracking the Plasma C-Terminal Agrin Fragment as a Biomarker of Neuromuscular Decline in 18- to 87-Year-Old Men5
Modern Biomarkers for Autism Spectrum Disorder: Future Directions5
The Future of Chemogenetics for the Treatment of Spasticity5
Cell Therapy of Severe Ischemia in People with Diabetic Foot Ulcers—Do We Have Enough Evidence?5
SARS-CoV-2 Testing Strategies in the Diagnosis and Management of COVID-19 Patients in Low-Income Countries: A Scoping Review5
Gestational Diabetes is Associated with an Increased Expression of miR-27a in Peripheral Blood Mononuclear Cells5
The Future of CAR T Therapeutics to Treat Autoimmune Disorders5
Expanded Alternatives of CRISPR–Cas9 Applications in Immunotherapy of Colorectal Cancer5
Clinical Progresses and Challenges of Bispecific Antibodies for the Treatment of Solid Tumors5
Clinical Validation of a Targeted RNA-Sequencing Assay for Driver Gene Alteration Detection in Non-Small Cell Lung Cancer4
Pitfalls in Cutaneous Melanoma Diagnosis and the Need for New Reliable Markers4
Multicenter In-House Evaluation of an Amplicon-Based Next−Generation Sequencing Panel for Comprehensive Molecular Profiling4
Proclarix, A New Biomarker for the Diagnosis of Clinically Significant Prostate Cancer: A Systematic Review4
Multicenter Performance Evaluation of the Revogene® GBS DS Real-Time PCR Assay for Group B Streptococcus Detection During Labor4
Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option4
Single-Cell Sequencing in Neurodegenerative Disorders4
Mycobacterium tuberculosis Detection Using CRISPR Technology: An Updated Systematic Review and Meta-analysis4
MicroRNA-146a Signature in Psoriasis: A Systematic Review and Meta-Analysis4
Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid Biopsy4
Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis4
Digital PCR-Based Method for Detecting CDKN2A Loss in Brain Tumours4
Smelling the Disease: Diagnostic Potential of Breath Analysis3
Prevalence of NTRK Fusions in Canadian Solid Tumour Cancer Patients3
Development of a Novel Internally Controlled HrpB1 Gene-Based Real-Time qPCR Assay for Detection of Burkholderia pseudomallei3
Clinical Performance of the cobas Liat SARS-CoV-2 & Influenza A/B Assay in Nasal Samples3
Biomarker Determinants of Early Anthracycline-Induced Left Ventricular Dysfunction in Breast Cancer: A Systematic Review and Meta-Analysis3
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin3
Gene Therapies in Clinical Development to Treat Retinal Disorders3
Clinical Utility of Implementing a Frontline NGS-Based DNA and RNA Fusion Panel Test for Patients with Suspected Myeloid Malignancies3
Clinical Potential of Expanded Noninvasive Prenatal Testing for Detection of Aneuploidies and Microdeletion/Microduplication Syndromes3
The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications3
Immune Checkpoint Blockade Therapy for Breast Cancer: Lessons from Epithelial–Mesenchymal Transition3
Diagnostic Potential of Cross-Specimen microRNA Panels as Biomarkers for Colorectal Cancer: A Systematic Review and Meta-analysis3
0.11516499519348