OOIR: Observatory of International Research

Papers

(The median citation count of Pediatric Drugs is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
An Update on the Management of Childhood-Onset Systemic Lupus Erythematosus	69
Neurocognitive Effects of Antiseizure Medications in Children and Adolescents with Epilepsy	43
Recent Developments and Advances in Atopic Dermatitis: A Focus on Epidemiology, Pathophysiology, and Treatment in the Pediatric Setting	38
Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2	34
Drug Treatment of Epilepsy Neuropsychiatric Comorbidities in Children	30
Assessment and Management of Acute Disseminated Encephalomyelitis (ADEM) in the Pediatric Patient	30
Potential Antibiotics for the Treatment of Neonatal Sepsis Caused by Multidrug-Resistant Bacteria	29
Dupilumab Treatment in Children Aged 6–11 Years With Atopic Dermatitis: A Multicentre, Real-Life Study	28
The Use of Linaclotide in Children with Functional Constipation or Irritable Bowel Syndrome: A Retrospective Chart Review	22
Lidocaine Infusions for Pain Management in Pediatrics	22
Phentermine/Topiramate: Pediatric First Approval	21
Benefits and Risks of Antidepressant Drugs During Pregnancy: A Systematic Review of Meta-analyses	20
Sodium Thiosulfate: Pediatric First Approval	20
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years	19
Letermovir for Prophylaxis and Pre-emptive Therapy of Cytomegalovirus Infection in Paediatric Allogeneic Haematopoietic Cell Transplant Patients	19
Viloxazine: Pediatric First Approval	19
An Update on CFTR Modulators as New Therapies for Cystic Fibrosis	19
Managing Adverse Events Associated with Dinutuximab Beta Treatment in Patients with High-Risk Neuroblastoma: Practical Guidance	19
Laboratory Safety of Dupilumab in Patients Aged 6–11 Years with Severe Atopic Dermatitis: Results from a Phase III Clinical Trial	18
Secukinumab: A Review in Moderate to Severe Pediatric Plaque Psoriasis	18
An Update of Pharmacological Management in Children with Functional Constipation	18
Managing Patient Pressure to Prescribe Antibiotics in the Clinic	16
Ranibizumab: A Review in Retinopathy of Prematurity	16
Pain Management in Children: NSAID Use in the Perioperative and Emergency Department Settings	15
Navigating the Regulatory Landscape to Develop Pediatric Oncology Drugs: Expert Opinion Recommendations	14

Impact of Antiseizure Medications on Appetite and Weight in Children	14
Safety of Quinolones in Children: A Systematic Review and Meta-Analysis	13
Targeted Therapy for Pediatric Psoriasis	11
Optimizing the Use of Antibiotic Agents in the Pediatric Intensive Care Unit: A Narrative Review	11
Metamizole Use in Children: Analysis of Drug Utilisation and Adverse Drug Reactions at a German University Hospital between 2015 and 2020	11
A Mixed-Methods Analysis of Medication Safety Incidents Reported in Neonatal and Children’s Intensive Care	11
Subgroup Analysis of Crisaborole for Mild-to-Moderate Atopic Dermatitis in Children Aged 2 to < 18 Years	10
Executive Function Outcome of Treatment with Viloxazine Extended-Release Capsules in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Post-Hoc Analysis of Four Randomized Clin	10
Ceftaroline Fosamil for Treatment of Pediatric Complicated Skin and Soft Tissue Infections and Community-Acquired Pneumonia	10
Teriflunomide: Pediatric First Approval	10
Efficacy and Safety of the Adjuvant Use of Probiotic Bacillus clausii Strains in Pediatric Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study	10
Effect of Mirtazapine on Nausea in Children with Functional Nausea and Functional Dyspepsia Postprandial Distress Syndrome	10
Medication and Fluid Management of Pediatric Sepsis and Septic Shock	9
Pharmacokinetics of Ceftazidime in Children and Adolescents with Obesity	9
Cardiovascular Drug Therapy during Interstage After Hybrid Approach: A Single-Center Experience in 51 Newborns with Hypoplastic Left Heart	9
Tyrosine Kinase Inhibitors and Beyond for Chronic Myeloid Leukemia in Children	9
A Review of Histamine-2 Receptor Antagonist and Proton Pump Inhibitor Therapy for Gastroesophageal Reflux Disease in Neonates and Infants	8
Lonapegsomatropin: Pediatric First Approval	8
What Role for Long-Acting Injectable Antipsychotics in Managing Schizophrenia Spectrum Disorders in Children and Adolescents? A Systematic Review	8
Deferred Consent in Neonatal Clinical Research: Why, When, How?	8
Managing Antiphospholipid Syndrome in Children and Adolescents: Current and Future Prospects	8
Best Evidence-Based Dosing Recommendations for Dexmedetomidine for Premedication and Procedural Sedation in Pediatrics: Outcome of a Risk-Benefit Analysis By the Dutch Pediatric Formulary	8
Prescribing Patterns and Impact of Factors Associated with Time to Initial Biologic Therapy among Children with Non-systemic Juvenile Idiopathic Arthritis	8
Pharmacotherapy for Spinal Muscular Atrophy in Babies and Children: A Review of Approved and Experimental Therapies	8
Immunosuppression Regimens for Intestinal Transplantation in Children	8
Laboratory Safety from a Randomized 16-Week Phase III Study of Dupilumab in Children Aged 6 Months to 5 Years with Moderate-to-Severe Atopic Dermatitis	8
Targeted Therapy in Pediatric AML: An Evolving Landscape	7
Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population	7
Treatment Options in Pediatric Behçet’s Disease	7
Immunotherapies for Pediatric Solid Tumors: A Targeted Update	7
Efficacy of Secukinumab Across Subgroups and Overall Safety in Pediatric Patients with Moderate to Severe Plaque Psoriasis: Week 52 Results from a Phase III Randomized Study	7
Asparaginase-Associated Pancreatitis in Pediatric Patients with Acute Lymphoblastic Leukemia: Current Perspectives	7
Prucalopride for Treatment of Upper Gastrointestinal Symptoms in Children	7
The Effect of Alfentanil on Emergence Delirium Following General Anesthesia in Children: A Randomized Clinical Trial	7
Haloperidol and Quetiapine for the Treatment of ICU-Associated Delirium in a Tertiary Pediatric ICU: A Propensity Score-Matched Cohort Study	7
Interventions to Reduce Pediatric Prescribing Errors in Professional Healthcare Settings: A Systematic Review of the Last Decade	7
Paradoxical Psoriasis in Children Receiving Anti-TNFα Treatment for Inflammatory/autoimmune Disease	6
Enhancing Mood, Cognition, and Quality of Life in Pediatric Multiple Sclerosis	6
Effectiveness and Safety of Adalimumab, Etanercept and Ustekinumab for Severe Psoriasis in Children Under 12 Years of Age: A French-Italian Daily Practice Cohort (BiPe Jr)	6
Medical Management of Infantile Hemangiomas: An Update	6
Hemodynamic Quality Improvement Bundle to Reduce the Use of Inotropes in Extreme Preterm Neonates	6
Developments in the Management of Severe Asthma in Children and Adolescents: Focus on Dupilumab and Tezepelumab	6
Acute Tolerability of Methylphenidate in Treatment-Naïve Children with ADHD: An Analysis of Naturalistically Collected Data from Clinical Practice	6
Management of IgA Vasculitis with Nephritis	6
Pharmacokinetics of l-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension	6
Safety of Ferric Carboxymaltose in Children: Report of a Case Series from Greece and Review of the Literature	6
Drug-Induced Hearing Loss in Children: An Analysis of Spontaneous Reports in the French PharmacoVigilance Database	6
Emerging Treatments for Childhood Interstitial Lung Disease	6
Managing Lupus Nephritis in Children and Adolescents	6
Pediatric Urologic Surgery: Reducing Opioid Use	5

Mirabegron: Pediatric First Approval	5
Assessment of the Effects of a High Amikacin Dose on Plasma Peak Concentration in Critically Ill Children	5
Therapeutic Approaches in Heart Failure with Preserved Ejection Fraction (HFpEF) in Children: Present and Future	5
Mechanism-Based Pharmacological Treatment for Chronic Non-cancer Pain in Adolescents: Current Approaches and Future Directions	5
Intravenous Golimumab in Patients with Polyarticular Juvenile Idiopathic Arthritis and Juvenile Psoriatic Arthritis and Subcutaneous Ustekinumab in Patients with Juvenile Psoriatic Arthritis: Extrapol	5
Fetal, Preterm, and Term Neonate Exposure to Remifentanil: A Systematic Review of Efficacy and Safety	5
Respiratory Syncytial Virus Prefusion F Subunit Vaccine: First Approval of a Maternal Vaccine to Protect Infants	4
Pharmacological Management of Atypical Hemolytic Uremic Syndrome in Pediatric Patients: Current and Future	4
Efficacy and Safety of Tacrolimus in the Treatment of Pediatric Henoch–Schönlein Purpura Nephritis	4
Clinical and Economic Evaluation of the Impact of Midazolam on Morphine Therapy for Pain Relief in Critically Ill Ventilated Infants with Respiratory Distress Syndrome	4
Effectiveness and Safety of Ustekinumab for Pediatric Inflammatory Bowel Disease: A Systematic Review	4
20‑Valent Pneumococcal Conjugate Vaccine: Pediatric First Approval	4
Multidisciplinary Clinical Care in the Management of Patients Receiving Anti-GD2 Immunotherapy for High-Risk Neuroblastoma	4
The Management of Burn Pain in a Pediatric Burns-Specialist Hospital	4
Real-Life Use of Biosimilars in Pediatric Inflammatory Bowel Disease: A Nation-Wide Web Survey on Behalf of the SIGENP IBD Working Group	4
Analysis of Risk Factors for Chloral Hydrate Sedative Failure with Initial Dose in Pediatric Patients: a Retrospective Analysis	4
Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children: Rationale and Progress to Date	4
Mechanistic Links Between Obesity and Airway Pathobiology Inform Therapies for Obesity-Related Asthma	4
Amphotericin B in Pediatrics: Analysis by Age Stratification Suggests a Greater Chance of Adverse Events from 13 Months of Age Onwards	4
Treatment of Langerhans Cell Histiocytosis and Histiocytic Disorders: A Focus on MAPK Pathway Inhibitors	4
Slower Recovery with Early Lopinavir/Ritonavir use in Pediatric COVID-19 Patients: A Retrospective Observational Study	3
Evaluating and Mitigating Risk of Acute Kidney Injury with the Combination of Vancomycin and Piperacillin-Tazobactam in Children	3
Drug Treatment of Heart Failure in Children: Gaps and Opportunities	3
Common Selfcare Indications of Pain Medications in Children	3
The Future of Advanced Therapies for Pediatric Crohn’s Disease	3
Scope of JAK Inhibitors in Children: Recent Evidence and Way Forward	3
Efficacy and Costs of Three Pharmacotherapies for Patent Ductus Arteriosus Closure in Premature Infants	3
Management of Hospitalized Respiratory Syncytial Virus Bronchiolitis in the Pediatric Ward in Spain: Assessing the Impact of a New Clinical Practice Protocol	3
A Pilot Comparison of High- Versus Low-Tech Palatability Assessment Tools in Young Children	3
Perioperative Indications for Gabapentinoids in Pediatrics: A Narrative Review	3
Topical Management of Pediatric Psoriasis: A Review of New Developments and Existing Therapies	3
Treatment Options for Juvenile Pityriasis Rubra Pilaris	3
Enteral and Parenteral Treatment with Caffeine for Preterm Infants in the Delivery Room: A Randomised Trial	3
Linking Genetic Diagnosis to Therapeutic Approach in Very Early Onset Inflammatory Bowel Disease: Pharmacologic Considerations	3
Toxicity Spectrum of Anti-GD2 Immunotherapy: A Real-World Study Leveraging the US Food and Drug Administration Adverse Event Reporting System	3
Intrapyloric Botulinum Toxin A Injection for Gastroparesis and Functional Upper Gastrointestinal Symptoms in Children: Mayo Clinic Experience, Review of the Literature, and Meta-analysis	3
Interventions for the Management of Pain and Sedation in Newborns Undergoing Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy: A Systematic Review	3
Randomized Clinical Trial of Metoclopramide as Prophylaxis of Gastroesophageal Reflux Disease in Preterm Infants	3
Diagnosis and Management of the Systemic Juvenile Idiopathic Arthritis Patient with Emerging Lung Disease	3
Ibrutinib: Pediatric First Approval	3
Secondary Dysgammaglobulinemia in Children with Hematological Malignancies Treated with Targeted Therapies	3
Can Pediatric Heart Failure Therapy Be Improved? Yes It Can, But…	3
Practical Approach to Diagnosis and Management of IL-1-Mediated Autoinflammatory Diseases (CAPS, TRAPS, MKD, and DIRA)	2
High-Concentration Intravenous Immunoglobulin May Influence the Course of Fever and Rate of Reported Treatment Resistance in Children With Kawasaki Disease: A Single-Center Retrospective Analysis	2
Infections in Children Aged 6 Months to 5 Years Treated with Dupilumab in a Placebo-Controlled Clinical Trial of Moderate-to-Severe Atopic Dermatitis	2
Ewing Sarcoma Drug Therapy: Current Standard of Care and Emerging Agents	2
Pharmacotherapy of Disruptive Behaviors in Children with Intellectual Disabilities	2
Bosutinib: Pediatric First Approval	2
Paediatric Agranulocytosis Associated with Metamizole Treatment	2
Personalized Dosing of Medicines for Children: A Primer on Pediatric Pharmacometrics for Clinicians	2
Macitentan in the Young—Mid-term Outcomes of Patients with Pulmonary Hypertensive Vascular Disease treated in a Pediatric Tertiary Care Center	2
Characterization of Cardiac Function by Echocardiographic Global Longitudinal Strain in a Cohort of Children with Neurofibromatosis Type 1 Treated with Selumetinib	2
Outcomes of Children with Fetal and Lactation Immunosuppression Exposure Born to Female Transplant Recipients	2
Thromboprophylaxis for Coagulopathy Related to COVID-19 in Pediatrics: A Narrative Review	2
Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and Prevention	2
Pitolisant: Pediatric First Approval	2
Golimumab in Children with Chronic Recurrent Multifocal Osteomyelitis: A Case Series and Review of the Literature	2
Pediatric Status Epilepticus: Treat Early and Avoid Delays	2
Dabigatran Etexilate: A Review in Pediatric Venous Thromboembolism	2
Cardiac Hypertrophy Associated with Insulin Therapy in Extremely Preterm Infants	2
CROCuS, a Phase II Study Evaluating the Antiviral Activity, Clinical Outcomes, and Safety of Rilematovir in Children Aged ≥ 28 Days and ≤ 3 Years with Acute Respiratory Tract Infection Due to Respirat	2
Drug Treatment of Low Bone Mass and Other Bone Conditions in Pediatric Patients	2
Population Pharmacokinetics of Moxifloxacin in Children	2
Azacitidine (Vidaza®) in Pediatric Patients with Relapsed Advanced MDS and JMML: Results of a Phase I/II Study by the ITCC Consortium and the EWOG-MDS Group (Study ITCC-015)	2
Therapeutic Drug Monitoring of Voriconazole in Critically Ill Pediatric Patients: A Single-Center Retrospective Study	2