Drugs & Aging

Article	Citations
Relationship Amongst Vitamin K Status, Vitamin K Antagonist Use and Osteoarthritis: A Review	84
An Educational Intervention to Promote Central Nervous System-Active Deprescribing in Dementia: A Pilot Study	51
Systemic Treatment for Older Patients with Unresectable Hepatocellular Carcinoma	44
Healthcare Costs Associated with Potentially Inappropriate Medication Prescribing Detected by Computer Algorithm Among Older Patients	36
The Association of Gabapentin Initiation with Cognitive and Behavioral Changes in Older Adults with Cognitive Impairment: A Retrospective Cohort Study	34
Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees	32
Sodium-Glucose Cotransporter 2 Inhibitors in Frail Patients with Heart Failure: Clinical Experience of a Heart Failure Unit	28
Ghent Older People’s Prescriptions Community Pharmacy Screening (GheOP3S)-Tool Version 2: Update of a Tool to Detect Drug-Related Problems in Older People in Primary Care	27
Clinician and Family Caregiver Perspectives on Deprescribing Chronic Disease Medications in Older Nursing Home Residents Near the End of Life	27
Hallucinations, Antipsychotic Use, and Mortality in Older Adults with Dementia: Retrospective Cohort Study of Two Medicare-Linked National Health Surveys	25
The Information-Seeking Behavior and Unmet Knowledge Needs of Older Medicinal Cannabis Consumers in Canada: A Qualitative Descriptive Study	25
Direct Oral Anticoagulants and Non-valvular Atrial Fibrillation: Compliance with Dose Level Guidelines in Patients Aged 80 Years and Over	25
Unlocking Deprescribing Potential in Nursing Homes: Insights from a Focus Group Study with Healthcare Professionals	24
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders	23
Low-Dose Glucocorticoids in Older Patients with Rheumatoid Arthritis: What Does the Evidence Say?	21
Prescribing Appropriate Medicines to Older Adults: A Finnish Experience with the Web-Based Meds75+ Database	21
Clinical Considerations for Insulin Therapy in Older Adults with Type 1 Diabetes	20
Seborrheic Dermatitis in Older Adults: Pathogenesis and Treatment Options	20
Drug Survival, Safety, and Effectiveness of Biologics in Older Patients with Psoriasis: A Comparison with Younger Patients—A BioCAPTURE Registry Study	20
A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alz	19
Geriatric Assessment in the Era of Targeted and Immunotherapy	19
Pharmacotherapies in Older Adults with COPD: Challenges and Opportunities	18
Decreased Kidney Function Explains Higher Vancomycin Exposure in Older Adults	18
Frequency and Acceptance of Clinical Decision Support System-Generated STOPP/START Signals for Hospitalised Older Patients with Polypharmacy and Multimorbidity	18
Impact of Fall Risk and Direct Oral Anticoagulant Treatment on Quality-Adjusted Life-Years in Older Adults with Atrial Fibrillation: A Markov Decision Analysis	18

Current Therapies and Drug Development Pipeline in Lewy Body Dementia: An Update	16
Medical Cannabis Use Among Older Adults in Canada: Self-Reported Data on Types and Amount Used, and Perceived Effects	15
Fall-Risk-Increasing Drugs and Gait Performance in Community-Dwelling Older Adults: Exploratory Results from the Gait and Brain Study	15
Benzodiazepine Receptor Agonists Use and Cessation Among Multimorbid Older Adults with Polypharmacy: Secondary Analysis from the OPERAM Trial	15
Temporal Trends Over Two Decades in the Use of Anticholinergic Drugs Among Older Community-Dwelling People in Helsinki, Finland	15
Association between the Use of Suvorexant and Hip Fracture in Older Adults in Japan Using a Nationwide Administrative Claims Database: A Matched Case–Control Study	14
Pharmacological Management of IgG4-Related Disease: From Traditional to Mechanism-Based Targeted Therapies	13
Trends, Patterns and Associated User Characteristics of Antidepressant Prescriptions in Older Adults: A Nationwide Descriptive Cohort Study in Denmark	13
The Prognostic Utility of Anticholinergic Burden Scales: An Integrative Review and Gap Analysis	13
Elevating Safe Use of Over-The-Counter Medications in Older Adults: A Narrative Review of Pharmacy Involved Interventions and Recommendations for Improvement	13
A Systematic Review of the Current Evidence from Randomised Controlled Trials on the Impact of Medication Optimisation or Pharmacological Interventions on Quantitative Measures of Cognitive Function i	13
Postoperative Pain Treatment in Patients with Dementia: A Retrospective Observational Study	13
What Makes Deprescription of Psychotropic Drugs in Nursing Home Residents with Dementia so Challenging? A Qualitative Systematic Review of Barriers and Facilitators	13
Optimizing Medications with the Geriatrics 5Ms: An Age-Friendly Approach	12
The FORTA (Fit fOR The Aged) List 2021: Fourth Version of a Validated Clinical Aid for Improved Pharmacotherapy in Older Adults	11
Risk factors predictive of adverse drug events and drug-related falls in aged care residents: secondary analysis from the ReMInDAR trial	11
Topical Medications for Chronic Itch in Older Patients: Navigating a Pressing Need	11
Real-World Drug Survival of Biologics and Targeted Synthetic Disease-Modifying Anti-rheumatic Drugs Among Patients with Psoriatic Arthritis	11
Post-Stroke Depression in Older Adults: An Overview	11
Hormonal Agents for the Treatment of Depression Associated with the Menopause	11
Vaccination in Older Adults: An Underutilized Opportunity to Promote Healthy Aging in India	11
From Drugs to Dry Mouth: A Systematic Review Exploring Oral and Psychological Health Conditions Associated with Dry Mouth in Older Adults with Polypharmacy	10
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma in Older Patients: Are New Agents Bringing New Hope?	10
Authors’ Reply to Moura et al.: “Safety of Janus Kinase Inhibitors in Older Patients: A Focus on the Thromboembolic Risk”	10
Complement Mediators in Development to Treat Age-Related Macular Degeneration	10
Association of Potentially Inappropriate Medication Classes with Mortality Risk Among Older Adults Initiating Hemodialysis	10
Respiratory Syncytial Virus Infection in Older Adults: An Update	10
Factors Associated with Psychotropic Medication Use in People Living with Dementia in the Community: A Systematic Review and Meta-Analysis	10
Minimising Harm and Managing Pain: Deprescribing Opioids in Older Adults	9
TANGO: Development of Consumer Information Leaflets to Support TAperiNG of Opioids in Older Adults with Low Back Pain and Hip and Knee Osteoarthritis	9
Treating LUTS in Men with Benign Prostatic Obstruction: A Review Article	9
Estimating the Time to Benefit for Therapies in Heart Failure with Reduced Ejection Fraction: A Case Study of Sacubitril-Valsartan Using Reconstructed Data from a Randomized Controlled Trial	9
The Difficulties of Managing Pain in People Living with Frailty: The Potential for Digital Phenotyping	9
Efficacy and Safety of Oral P2Y12 Inhibitors in Older Patients with Acute Coronary Syndrome: A Frequentist Network Meta-Analysis	9
Acknowledgement to Referees	9
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults	9
Prevalence and Factors Associated with Cumulative Anticholinergic Burden Among Older Long-Stay Nursing Home Residents with Overactive Bladder	9
Prescribing Cascades with Recommendations to Prevent or Reverse Them: A Systematic Review	9
Hormone Treatment and Alzheimer’s Disease: Déjà Vu or Confused All Over Again?	9
Management of Scleritis in Older Adults	9
Measuring Quality of Life in Deprescribing Trials: A Scoping Review	8
Priority-Setting to Address the Geriatric Pharmacoparadox for Pain Management: A Nursing Home Stakeholder Delphi Study	8
Attitudes to Drug Use in Residential Aged Care Facilities: A Cross-Sectional Survey of Nurses and Care Staff	8
Ulcerative Colitis in Adulthood and in Older Patients: Same Disease, Same Outcome, Same Risks?	8
A Cohort Study on Influenza Vaccine and All-Cause Mortality in Older Adults: Methodological Concerns and Public Health Implications	8
Individualized Dosing Patterns in the Treatment of Older Patients with Gastrointestinal Stromal Tumors: Results of a Registry-Based Observational National Cohort Study Including 871 Patients	8
Anticholinergic Exposure, Drug Dose and Postoperative Delirium: Comparison of Dose-Related and Non-Dose-Related Anticholinergic Burden Scores in a Retrospective Cohort Study of Older Orthopaedic and T	7
Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models	7
Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia	7
Individualizing Antiretroviral Therapy in the Older Patient	7

Gout Flare Burden, Diagnosis, and Management: Navigating Care in Older Patients with Comorbidity	7
Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management	7
Safety and Tolerability of Antimicrobial Agents in the Older Patient	7
Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care	6
Medication Complexity Among Older Adults with HF: How Can We Assess Better?	6
Rho Kinase Inhibitors: Strategies in Glaucoma Treatment in Older Adults	6
Hypertension Treatment in Frail Older Adults: A Systematic Review and Appraisal of Guidelines	6
Pre-clinical Models for Geriatric Pharmacotherapy	6
Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study	6
Fibromyalgia in Older Individuals	6
Discontinuation of Loop Diuretics in Older Patients with Chronic Stable Heart Failure: A Narrative Review	6
Adjunctive Perampanel in Older Patients With Epilepsy: A Multicenter Study of Clinical Practice	6
Changes in Medication Complexity and Post-Hospitalization Outcomes in Older Adults Hospitalized for Heart Failure	6
Considerations for Choosing First-Line Urate-Lowering Treatment in Older Patients with Comorbid Conditions	6
Do Proton Pump Inhibitors Reduce Upper Gastrointestinal Bleeding in Older Patients with Atrial Fibrillation Treated with Oral Anticoagulants? A Nationwide Cohort Study in France	6
Lipid-Lowering Medications are Associated with Reduced Sarcopenia-Related Quality of Life in Older Adults with Hyperlipidemia	6
First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis	6
Correction to: A Structured Literature Review and International Consensus Validation of FORTA Labels of Oral Anticoagulants for Long-Term Treatment of Atrial Fibrillation in Older Patients (OAC-FORTA	5
Cumulative Anticholinergic Burden and its Predictors among Older Adults with Alzheimer’s Disease Initiating Cholinesterase Inhibitors	5
Repurposing Drugs for Diabetes Mellitus as Potential Pharmacological Treatments for Sarcopenia – A Narrative Review	5
Pharmacological Treatment in the Management of Glenohumeral Osteoarthritis	5
Crushed Tablet Administration for Patients with Dysphagia and Enteral Feeding: Challenges and Considerations	5
Oral Corticosteroids for Skin Disease in the Older Population: Minimizing Potential Adverse Effects	5
Correction to: The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation	5
Antipsychotic Initiation Among Older Dementia Patients Using Cholinesterase Inhibitors: A National Retrospective Cohort Study	5
Management of Hypertension in the Elderly and Frail Patient	5
HOSPITAL Score and LACE Index to Predict Mortality in Multimorbid Older Patients	5
Pharmacotherapy for Spine-Related Pain in Older Adults	5
Primary-Care Prescribers’ Perspectives on Deprescribing Opioids and Benzodiazepines in Older Adults	5
Correction to: Hexanic Extract of Serenoa repens (Permixon®): A Review in Symptomatic Benign Prostatic Hyperplasia	5
Older Canadians’ Perceptions of the Safety, Effectiveness and Accessibility of Cannabis for Medicinal Purposes: A Cross-Sectional Analysis	5
Highly Variable Paracetamol Pharmacokinetics After Multiple Oral Dosing in Frail Older People: A Population Pharmacokinetic Analysis	5
Effects of Resveratrol Supplementation on the Cognitive Function of Patients with Alzheimer's Disease: A Systematic Review of Randomized Controlled Trials	5
Patterns of Comorbidities and Prescribing and Dispensing of Non-steroidal Anti-inflammatory Drugs (NSAIDs) Among Patients with Osteoarthritis in the USA: Real-World Study	5
Prevalence of Adverse Drug Reactions in Hospital Among Older Patients with and Without Dementia	5
Difficult-to-Treat Rheumatoid Arthritis in Older Adults: Implications of Ageing for Managing Patients	4
Comment on: “Polypharmacy and Antibody Response to SARS-CoV-2 Vaccination in Residents of Long-Term Care Facilities: the GeroCovid Study”	4
Treatment of Metastatic Gastrointestinal Stromal Tumors (GIST): A Focus on Older Patients	4
Inappropriate Combined Antiplatelet and Anticoagulant Therapy in Older Patients with Atrial Fibrillation: Trend over Time (2009–18)	4
Problematic Opioid Use Among Older Adults: Epidemiology, Adverse Outcomes and Treatment Considerations	4
The Future of Incretin-Based Approaches for Neurodegenerative Diseases in Older Adults: Which to Choose? A Review of their Potential Efficacy and Suitability	4
Evaluation and Treatment of Acute Trauma Pain in Older Adults	4
National Trends in Statin Use among the United States Nursing Home Population (2011–2016)	4
A Motivational Interviewing Intervention to Improve Adherence to ACEIs/ARBs among Nonadherent Older Adults with Comorbid Hypertension and Diabetes	4
Treating Hypertension in Older Adults in Light of the Recent STEP Trial: Can We Implement the Findings in Geriatric Practice?	4
Anticholinergic Burden and Associated Healthcare Resource Utilization in Older Adults with Overactive Bladder	4
Identifying Residents Who May Benefit from an Analgesic Review: Applying Analgesic Indicators in Residential Aged Care Services	4
Risk of Fractures in Older Adults with Chronic Non-cancer Pain Receiving Concurrent Benzodiazepines and Opioids: A Nested Case–Control Study	4
Deprescribing Medications that Increase the Risk of Falls in Older People: Exploring Doctors' Perspectives Using the Theoretical Domains Framework (TDF)	4
Real-World Experience of Immune-Checkpoint Inhibitors in Older Patients with Advanced Cutaneous Squamous Cell Carcinoma	4
Evaluation of Renal Function Testing in Older Australian Veterans Dispensed Medicines that Require Renal Function Monitoring	4
Acknowledgement to Referees	4
Drug–Drug Interactions in Patients with COVID-19 in Nursing Homes	4
Dosage Optimization of Digoxin in Older Patients with Heart Failure and Chronic Kidney Disease: A Population Pharmacokinetic Analysis	4
Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing	4
Psychotropic Drug Prescription in Nursing Homes During the COVID-19 Pandemic	4
A Proactive Approach to Prevent Hematopoietic Exhaustion During Cancer Chemotherapy in Older Patients: Temporary Cell-Cycle Arrest	4
Correlates of Opioid Use Among Ontario Long-Term Care Residents and Variation by Pain Frequency and Intensity: A Cross-sectional Analysis	4
Clinical Experience with Extended-Release Tacrolimus in Older Adult Kidney Transplant Recipients: A Retrospective Cohort Study	3
Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany	3
Prospective Observational Study Evaluating the Prognostic Value of the G8 Screening Tool for Extensive-Stage Small Cell Lung Cancer Patients Who Received Programmed Death-Ligand 1 Inhibitor plus Plati	3
Safety of Remdesivir for Patients 80 Years of Age or Older with Coronavirus Disease 2019 (COVID-19)	3
Management of Advanced Urothelial Carcinoma in Older and Frail Patients: Have Novel Treatment Approaches Improved Their Care?	3
Status Epilepticus in Older Adults: Diagnostic and Treatment Considerations	3
Efficacy and Safety of Fixed-Dose Combinations for Pain in Older Adults	3
Pharmacological Pain Treatment in Older Persons	3
Implications of Adverse Outcomes Associated with Antipsychotics in Older Patients with Dementia: A 2011–2022 Update	3
Relationship Between Frailty and Diabetic Pharmacologic Therapy in Older Adults with Type 2 Diabetes: A Cross-Sectional Study	3
Helicobacter pylori Eradication Treatment in Older Patients	3
Pharmacological Risk Assessment Among Older Patients with Polypharmacy Using the Clinical Decision Support System Janusmed Risk Profile: A Cross-Sectional Register Study	3
Secular Trends in Central Nervous System-Active Polypharmacy Among Serial Cross-Sections of US Adults, 2009–2020	3
Direct Oral Anticoagulants in Older and Frail Patients with Atrial Fibrillation: A Decade of Experience	3
Assessing Long-Term Adverse Outcomes in Older Kidney Transplant Recipients: A Propensity Score-Matched Comparison of Early Steroid Withdrawal Versus Continuous Steroid Immunosuppression Using a Large	3
Considerations for Anesthesia in Older Adults with Cannabis Use	3
Ageing with HIV: Medicine Optimisation Challenges and Support Needs for Older People Living with HIV: A Systematic Review	3
Topical Pharmacotherapy for Actinic Keratoses in Older Adults	3
Associated Factors to Efficacy and Tolerance of Immunotherapy in Older Patients with Cancer Aged 70 Years and Over: Impact of Coprescriptions	3
Psychotropic Medication Prescribing to Patients with Dementia Admitted to Acute Hospitals in Ireland	3
Pharmacological Treatments for Presbyopia	3
Platelet-Rich Plasma for Knee Osteoarthritis: What Does the Evidence Say?	3

Pilocarpine in the Treatment of Presbyopia: Progress, Issues, and Future Prospects	3
Correction to: SGLT2 Inhibitors in Older Adults with Heart Failure with Preserved Ejection Fraction	3
Efficacy and Safety of Daridorexant in Older and Younger Adults with Insomnia Disorder: A Secondary Analysis of a Randomised Placebo-Controlled Trial	3
Associations Between Midlife Anticholinergic Medication Use and Subsequent Cognitive Decline: A British Birth Cohort Study	2
Pharmacotherapeutic Management of Well-Differentiated Neuroendocrine Tumors in Older Patients: Current Status and Potential Therapies	2
The Impact of Polypharmacy on Management of Lower Urinary Tract Symptoms in Parkinson’s Disease	2
Therapeutic Recommendations for the Management of Older Adult Patients with Sjögren’s Syndrome	2
Aspiring to Reasonableness in Accelerated Approval: Anticipating and Avoiding the Next Aducanumab	2
Opioids and Falls Risk in Older Adults: A Narrative Review	2
Utility of Big Data to Explore Medication Adherence in Māori and Non-Māori Community-Dwelling Older Adults with Heart Failure in Aotearoa New Zealand: A Cross-sectional Study	2
An Updated Analysis of Psychotropic Medicine Utilisation in Older People in New Zealand from 2005 to 2019	2
Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross-sectional study	2
Correction: Treating Lower Urinary Tract Symptoms in Older Adults: Intravesical Options	2
The Risk of Falling and Consequences of Falling in Patients with Atrial Fibrillation Receiving Different Types of Anticoagulant	2
MediQuit, an Electronic Deprescribing Tool for Patients on Polypharmacy: Results of a Feasibility Study in German General Practice	2
Opioid Initiation and the Hazard of Falls or Fractures Among Older Adults with Varying Levels of Central Nervous System Depressant Burden	2
NSAIDs for Pain Control During the Peri-Operative Period of Hip Fracture Surgery: A Systematic Review	2
Pain Management in Older Adults with Chronic Wounds	2
Comparative Effectiveness and Safety of Ticagrelor Versus Clopidogrel for Elderly Chinese Patients Undergoing Percutaneous Coronary Intervention: A Single-Center Retrospective Cohort Study	2
Opioid Prescriptions for Low Back Pain among Military-Connected Older Adults Across Multiple Care Systems	2
Development of a Frailty Screening Tool Using Electronic Community Pharmacy Records	2
Management of Older Adults with Sickle Cell Disease: Considerations for Current and Emerging Therapies	2
Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study	2
Correction to: Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross‑sectional study	2
Correction to: Risk factors predictive of adverse drug events and drug-related falls in aged care residents: secondary analysis from the ReMInDAR trial	2
Development and Pilot Testing of an Algorithm-Based Approach to Anticholinergic Deprescribing in Older Patients	2
The PROMISING Project: A Pilot Study to Improve Geriatric Care Through a Pharmacist-Led Psychotropic Stewardship Program	2
The Prevalence of Adverse Drug Reactions and Adverse Drug Events from Heart Failure Medications in Frail Older Adults: A Systematic Review	2
Major Depressive Disorder in Older Patients as an Inflammatory Disorder: Implications for the Pharmacological Management of Geriatric Depression	2
The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation	2
ThinkCascades: A Tool for Identifying Clinically Important Prescribing Cascades Affecting Older People	2
Independent Association Between Use of Proton Pump Inhibitors and Muscle Wasting in Patients with Heart Failure: A Single-Center, Ambispective, Observational Study	2
The Relationship Between Antipsychotics, Cognitive Enhancers, and Major Adverse Cardiovascular/Cerebrovascular Events (MACCE) in Older Adults with Behavioral and Psychological Symptoms of Dementia	2
Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF: A Systematic Review and Meta-Analysis	2
Correction to: The FORTA (Fit fOR The Aged) List 2021: Fourth Version of a Validated Clinical Aid for Improved Pharmacotherapy in Older Adults	2
Exploring Sex, Gender, and Gender-Related Sociocultural Factors in Clinical Decision-Making for Older Adults Using a Prescribing Cascade Vignette: A Transnational Qualitative Study	2