Drugs & Aging

Article	Citations
Drug-Related Orthostatic Hypotension: Beyond Anti-Hypertensive Medications	61
Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management	59
Bimatoprost Implant: First Approval	45
Depression in Patients with Parkinson’s Disease: Current Understanding of its Neurobiology and Implications for Treatment	34
Romosozumab: A Review in Postmenopausal Osteoporosis	31
Safety of Janus Kinase Inhibitors in Older Patients: A Focus on the Thromboembolic Risk	31
Problematic Opioid Use Among Older Adults: Epidemiology, Adverse Outcomes and Treatment Considerations	28
Potentially Inappropriate Medications, Drug–Drug Interactions, and Anticholinergic Burden in Elderly Hospitalized Patients: Does an Association Exist with Post-Discharge Health Outcomes?	26
Adjunctive Perampanel in Older Patients With Epilepsy: A Multicenter Study of Clinical Practice	25
The FORTA (Fit fOR The Aged) List 2021: Fourth Version of a Validated Clinical Aid for Improved Pharmacotherapy in Older Adults	24
Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models	23
Drug–Drug Interactions and Prescription Appropriateness in Patients with COVID-19: A Retrospective Analysis from a Reference Hospital in Northern Italy	22
Attitudes Towards Deprescribing Among Older Adults with Limited Life Expectancy and Their Relatives: A Systematic Review	22
Immune Checkpoint Inhibitors for Patients Aged ≥ 75 Years with Advanced Cancer in First- and Second-Line Settings: A Meta-Analysis	22
Medical Cannabis Use Among Older Adults in Canada: Self-Reported Data on Types and Amount Used, and Perceived Effects	21
A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alz	20
Use of SGLT2 Inhibitors in Older Adults: Scientific Evidence and Practical Aspects	19
Opioids and Falls Risk in Older Adults: A Narrative Review	19
Pulmonary Tuberculosis in Older Adults: Increased Mortality Related to Tuberculosis Within Two Months of Treatment Initiation	18
Current Insights into Treating Vertigo in Older Adults	17
Efficacy and Safety of Once-Daily Vibegron for Treatment of Overactive Bladder in Patients Aged ≥65 and ≥75 Years: Subpopulation Analysis from the EMPOWUR Randomized, International, Phase III Study	16
Association Between Potentially Inappropriate Medications and Hospital Encounters Among Older Adults: A Meta-Analysis	16
Diagnosis and Management of Pain in Parkinson's Disease: A New Approach	16
Comparative Safety and Efficacy of Treatments for Overactive Bladder Among Older Adults: A Network Meta-analysis	15
Effects of Resveratrol Supplementation on the Cognitive Function of Patients with Alzheimer's Disease: A Systematic Review of Randomized Controlled Trials	15

Barriers and Enablers of Healthcare Providers to Deprescribe Cardiometabolic Medication in Older Patients: A Focus Group Study	15
Efficacy and Safety of Daridorexant in Older and Younger Adults with Insomnia Disorder: A Secondary Analysis of a Randomised Placebo-Controlled Trial	14
Safety and Tolerability Results from the PILLAR Study: A Phase IV, Double-Blind, Randomized, Placebo-Controlled Study of Mirabegron in Patients ≥ 65 years with Overactive Bladder-Wet	14
Hormonal Agents for the Treatment of Depression Associated with the Menopause	14
Prevalence of Musculoskeletal Pain and Analgesic Treatment Among Community-Dwelling Older Adults: Changes from 1999 to 2019	14
Diagnostic and Management Strategies for Patients with Chronic Prostatitis and Chronic Pelvic Pain Syndrome	13
Frequency and Acceptance of Clinical Decision Support System-Generated STOPP/START Signals for Hospitalised Older Patients with Polypharmacy and Multimorbidity	13
International Validation of the Turkish Inappropriate Medication Use in the Elderly (TIME) Criteria Set: A Delphi Panel Study	13
Assessment of Poor Inhaler Technique in Older Patients with Asthma or COPD: A Predictive Tool for Clinical Risk and Inhaler Performance	13
Pharmacotherapy for Spine-Related Pain in Older Adults	13
Onychomycosis in Older Adults: Prevalence, Diagnosis, and Management	12
Ghent Older People’s Prescriptions Community Pharmacy Screening (GheOP3S)-Tool Version 2: Update of a Tool to Detect Drug-Related Problems in Older People in Primary Care	12
Factors Affecting Prescriber Implementation of Computer-Generated Medication Recommendations in the SENATOR Trial: A Qualitative Study	12
Chronic Post-Surgical Pain in the Frail Older Adult	11
Medication Counselling in Older Patients Prior to Hospital Discharge: A Systematic Review	11
Short-Course Systemic and Topical Non-Steroidal Anti-Inflammatory Drugs: Impact on Adverse Renal Events in Older Adults with Co-Morbid Disease	11
Prevalence and Factors Associated with Potential Drug-Drug Interactions in Older Community-Dwelling Adults: A Prospective Cohort Study	11
Overactive Bladder in Frail Older Adults	11
Use and Deprescribing of Potentially Inappropriate Medications in Frail Nursing Home Residents	11
Predictors of Mortality in the Older Population: The Role of Polypharmacy and Other Medication and Chronic Disease-Related Factors	11
Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes	10
Ethnic Variations in the Quality Use of Medicines in Older Adults: Māori and Non-Māori in Aotearoa New Zealand	10
Safety of Remdesivir for Patients 80 Years of Age or Older with Coronavirus Disease 2019 (COVID-19)	10
Current Therapies and Drug Development Pipeline in Lewy Body Dementia: An Update	10
Safety, Effectiveness, and Immunogenicity 6 Months After BNT162B2 mRNA Vaccine in Frail Nursing Home Residents	10
Use of Hormone Therapy in Postmenopausal Women with Alzheimer’s Disease: A Systematic Review	10
Treatment of Seizures in Older Patients with Dementia	10
Frailty and Potentially Inappropriate Prescribing in Older People with Polypharmacy: A Bi-Directional Relationship?	10
Decision Tools and Studies to Improve the Diagnosis of Urinary Tract Infection in Nursing Home Residents: A Narrative Review	10
Ulcerative Colitis in Adulthood and in Older Patients: Same Disease, Same Outcome, Same Risks?	10
Trends in Anticoagulant Use at Nursing Home Admission and Variation by Frailty and Chronic Kidney Disease Among Older Adults with Atrial Fibrillation	9
Preoperative Comparison of Three Anticholinergic Drug Scales in Older Adult Patients and Development of Postoperative Delirium: A Prospective Observational Study	9
The Cross-Talk between Age, Hypertension and Inflammation in COVID-19 Patients: Therapeutic Targets	9
Pharmacist Identification of Medication Therapy Problems Involving Cognition Among Older Adults Followed by a Home-Based Care Team	9
A Structured Literature Review and International Consensus Validation of FORTA Labels of Oral Anticoagulants for Long-Term Treatment of Atrial Fibrillation in Older Patients (OAC-FORTA 2019)	9
Measuring Medication Self-Management Capacity: A Scoping Review of Available Instruments	9
Diabetic Kidney Disease in Older People with Type 2 Diabetes Mellitus: Improving Prevention and Treatment Options	9
Management of the Older Patient with Myelodysplastic Syndrome	9
Gout Flare Burden, Diagnosis, and Management: Navigating Care in Older Patients with Comorbidity	9
Differential Diagnoses and Clinical Implications of Medication Nonadherence in Older Patients with Chronic Kidney Disease: A Review	8
Safety and Tolerability of Natural and Synthetic Cannabinoids in Older Adults: A Systematic Review and Meta-Analysis of Open-Label Trials and Observational Studies	8
Implications of Adverse Outcomes Associated with Antipsychotics in Older Patients with Dementia: A 2011–2022 Update	8
Drug Survival, Safety, and Effectiveness of Biologics in Older Patients with Psoriasis: A Comparison with Younger Patients—A BioCAPTURE Registry Study	8
Differences in Health-Related Quality of Life Among Adults with a Potential Dihydropyridine Calcium Channel Blocker–Loop Diuretic Prescribing Cascade	8
Major Depressive Disorder in Older Patients as an Inflammatory Disorder: Implications for the Pharmacological Management of Geriatric Depression	8
The Future of Incretin-Based Approaches for Neurodegenerative Diseases in Older Adults: Which to Choose? A Review of their Potential Efficacy and Suitability	8
Attitudes to Drug Use in Residential Aged Care Facilities: A Cross-Sectional Survey of Nurses and Care Staff	8
What Makes Deprescription of Psychotropic Drugs in Nursing Home Residents with Dementia so Challenging? A Qualitative Systematic Review of Barriers and Facilitators	8
Effect of Antihypertensive and Statin Medication Use on Muscle Performance in Community-Dwelling Older Adults Performing Strength Training	8
Drug–Drug Interactions and Prescription Appropriateness at Hospital Discharge: Experience with COVID-19 Patients	8

ThinkCascades: A Tool for Identifying Clinically Important Prescribing Cascades Affecting Older People	8
Primary-Care Prescribers’ Perspectives on Deprescribing Opioids and Benzodiazepines in Older Adults	8
Safety and Effectiveness of Immune Checkpoint Inhibitors in Older Patients with Cancer: A Systematic Review of 48 Real-World Studies	7
Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study	7
Fibromyalgia in Older Individuals	7
Impact of Fall Risk and Direct Oral Anticoagulant Treatment on Quality-Adjusted Life-Years in Older Adults with Atrial Fibrillation: A Markov Decision Analysis	7
Use of Antibiotics in Chronic Obstructive Pulmonary Disease: What is Their Current Role in Older Patients?	7
Difficult-to-Treat Rheumatoid Arthritis in Older Adults: Implications of Ageing for Managing Patients	7
Safety and Effectiveness of Biologic Disease-Modifying Antirheumatic Drugs in Older Patients with Rheumatoid Arthritis: A Prospective Cohort Study	7
Next-Generation Androgen Receptor-Signaling Inhibitors for Prostate Cancer: Considerations for Older Patients	7
Aspiring to Reasonableness in Accelerated Approval: Anticipating and Avoiding the Next Aducanumab	7
Use of Antidepressants in Older People during a 10-Year Period: An Observational Study on Prescribed Doses and Serum Levels	7
Age-Related Lymphocyte Output During Disease-Modifying Therapies for Multiple Sclerosis	7
Pharmacological Treatment in the Management of Glenohumeral Osteoarthritis	7
Efficacy, Safety, and Accuracy of Intra-articular Therapies for Hand Osteoarthritis: Current Evidence	6
Safety of Pyrazinamide for the Treatment of Tuberculosis in Older Patients Over 75 Years of Age: A Retrospective Monocentric Cohort Study	6
A Cohort Study on Influenza Vaccine and All-Cause Mortality in Older Adults: Methodological Concerns and Public Health Implications	6
Optimizing the Treatment of Moderate-to-Severe Psoriasis in Older Adults	6
Management of Ambulatory Anesthesia in Older Adults	6
Scoping Review of Studies Evaluating Frailty and Its Association with Medication Harm	6
MediQuit, an Electronic Deprescribing Tool for Patients on Polypharmacy: Results of a Feasibility Study in German General Practice	6
Priority-Setting to Address the Geriatric Pharmacoparadox for Pain Management: A Nursing Home Stakeholder Delphi Study	6
Seborrheic Dermatitis in Older Adults: Pathogenesis and Treatment Options	6
Interprofessional Interventions Involving Pharmacists and Targeting the Medicines Management Process Provided to Older People Residing in Nursing Homes: A Systematic Review and Meta-Analysis of Random	6
Efficacy and Safety of the Association of Nimodipine and Choline Alphoscerate in the Treatment of Cognitive Impairment in Patients with Cerebral Small Vessel Disease. The CONIVaD Trial	6
Psychotropic Drug Prescription in Nursing Homes During the COVID-19 Pandemic	6
Therapeutic Options Under Development for Nonneovascular Age-Related Macular Degeneration and Geographic Atrophy	6
Managing Nocturia in Frail Older Adults	6
Anticholinergic Burden and Fractures: A Systematic Review with Methodological Appraisal	5
Bladder Dysfunction in Older Adults: The Botulinum Toxin Option	5
The Risk of Falling and Consequences of Falling in Patients with Atrial Fibrillation Receiving Different Types of Anticoagulant	5
The Prevalence of Adverse Drug Reactions and Adverse Drug Events from Heart Failure Medications in Frail Older Adults: A Systematic Review	5
Highly Variable Paracetamol Pharmacokinetics After Multiple Oral Dosing in Frail Older People: A Population Pharmacokinetic Analysis	5
Repurposing Drugs for Diabetes Mellitus as Potential Pharmacological Treatments for Sarcopenia – A Narrative Review	5
Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia	5
Systemic Treatment for Older Patients with Unresectable Hepatocellular Carcinoma	5
Polypharmacy and Aging in People Living with HIV: 6 Years of Experience in a Multidisciplinary Outpatient Clinic	5
Impact of Pharmacotherapy on Insomnia in Patients with Alzheimer’s Disease	5
A 12-Year Retrospective Study of the Prevalence of Anticholinergic Polypharmacy and Associated Outcomes Among Medicare Patients with Overactive Bladder in the USA	5
Clinical Experience with Extended-Release Tacrolimus in Older Adult Kidney Transplant Recipients: A Retrospective Cohort Study	5
Safety and Tolerability of Antimicrobial Agents in the Older Patient	5
A Multimorbidity-Based, Risk-Stratified Reanalysis of the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Trial	5
Sedative Load in Community-Dwelling Older Adults with Mild–Moderate Alzheimer’s Disease: Longitudinal Relationships with Adverse Events, Delirium and Falls	5
Sex Differences in Association Between Anti-Hypertensive Medications and Risk of COVID-19 in Middle-Aged and Older Adults	5
Trends in the Dispensing and Costs of Glucose-Lowering Medications Among Older Australians: Findings from National Claims Data	5
Recent Advances in the Management of Migraine in Older Patients	5
Deprescribing Medications that Increase the Risk of Falls in Older People: Exploring Doctors' Perspectives Using the Theoretical Domains Framework (TDF)	5
HOSPITAL Score and LACE Index to Predict Mortality in Multimorbid Older Patients	5
The EURO-FORTA (Fit fOR The Aged) List Version 2: Consensus Validation of a Clinical Tool for Improved Pharmacotherapy in Older Adults	4
Hand Grip Strength May Affect the Association Between Anticholinergic Burden and Mortality Among Older Patients Discharged from Hospital	4
Opioid Initiation and the Hazard of Falls or Fractures Among Older Adults with Varying Levels of Central Nervous System Depressant Burden	4
Treatment of Metastatic Gastrointestinal Stromal Tumors (GIST): A Focus on Older Patients	4
Optimizing Medications with the Geriatrics 5Ms: An Age-Friendly Approach	4
Renal Function, Cardiovascular Diseases, Appropriateness of Drug Prescription and Outcomes in Hospitalized Older Patients	4
Does Older Age have an Impact on Rituximab Efficacy and Safety? Results from the NOR-DMARD Register	4
Pharmacological Pain Treatment in 2012 and 2017 Among Older People with Major Neurocognitive Disorder	4
Therapeutic Recommendations for the Management of Older Adult Patients with Sjögren’s Syndrome	4
Feasibility of Intranasal Dexmedetomidine in Treatment of Postoperative Restlessness, Agitation, and Pain in Geriatric Orthopedic Patients	4
A Motivational Interviewing Intervention to Improve Adherence to ACEIs/ARBs among Nonadherent Older Adults with Comorbid Hypertension and Diabetes	4
An Analysis of Anesthesia Induction Dosing in Female Older Adults	4
Real-World Effectiveness and Safety of Apremilast in Older Patients with Psoriasis	4
Association between Statins Prescribed for Primary and Secondary Prevention and Major Adverse Cardiac Events among Older Adults with Frailty: A Systematic Review	4
Adjunctive Brivaracetam in Older Patients with Focal Seizures: Evidence from the BRIVAracetam add‑on First Italian netwoRk Study (BRIVAFIRST)	4
Persistence of Effect of Medication Review on Potentially Inappropriate Prescriptions in Older Patients Following Hospital Discharge	4
Risk of Serious Adverse Events Associated With Individual Cholinesterase Inhibitors Use in Older Adults With Dementia: A Population-Based Cohort Study	4
Neuropsychiatric Systemic Lupus Erythematosus in Older Adults: Diagnosis and Management	4
Management of Hypertension in the Elderly and Frail Patient	4
Vaccination in Older Adults: An Underutilized Opportunity to Promote Healthy Aging in India	4
Hexanic Extract of Serenoa repens (Permixon®): A Review in Symptomatic Benign Prostatic Hyperplasia	4
Non-steroidal Anti-inflammatory Drug Use and Risk of Age-Related Macular Degeneration in the California Teachers Study	4
Management of Hyperglycemia in Older Adults with Type 2 Diabetes	4
Benefit–Risk Assessment of Psychotropic Drugs in Older Patients with Chronic Obstructive Pulmonary Disease	3
Management of Advanced Urothelial Carcinoma in Older and Frail Patients: Have Novel Treatment Approaches Improved Their Care?	3
The Evolving Complexity of Treating Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer: Special Considerations in Older Breast Cancer Patients—Part II: M	3
Immunotherapy in Older Patients with Advanced Melanoma: A Review of the Current Evidence	3
Impact of Pharmaceutical Interventions with STOPP/START and PIM-Check in Older Hospitalized Patients: A Randomized Controlled Trial	3
Complement Mediators in Development to Treat Age-Related Macular Degeneration	3
Postoperative Pain Treatment in Patients with Dementia: A Retrospective Observational Study	3
Treatment Patterns of Lipid-Lowering Therapy in Patients with Coronary Artery Disease Aged Above and Below 75 Years: A Retrospective Cross-Sectional Study of 1500 Patients in a Tertiary Care Referral	3
Anticholinergic Burden Does Not Influence Delirium Subtype or the Delirium–Mortality Association in Hospitalized Older Adults: Results from a Prospective Cohort Study	3

Iterative Development of Clinician Guides to Support Deprescribing Decisions and Communication for Older Patients in Hospital: A Novel Methodology	3
Assessment of Comorbidity Burden and Treatment Response: Reanalysis of the SCD-HEFT Trial	3
Hypotension Under Antihypertensive Treatment and Incident Hospitalizations of Nursing Home Residents	3
Sex Differences in Antipsychotic and Benzodiazepine Prescribing Patterns: A Cohort Study of Newly Admitted Nursing Home Residents with Dementia in Ontario, Canada	3
Removal of Drugs for Alzheimer’s Disease from the List of Reimbursable Drugs in France: Analysis of Change in Drug Use, Disease Management and Cognition Using the National Alzheimer Data Bank (BNA)	3
SGLT2 Inhibitors in Older Adults with Heart Failure with Preserved Ejection Fraction	3
Anticholinergic Burden and Associated Healthcare Resource Utilization in Older Adults with Overactive Bladder	3
First-Line Biological Agents Plus Chemotherapy in Older Patients with Metastatic Colorectal Cancer: A Retrospective Pooled Analysis	3
Risk factors predictive of adverse drug events and drug-related falls in aged care residents: secondary analysis from the ReMInDAR trial	3
A Systematic Review of the Current Evidence from Randomised Controlled Trials on the Impact of Medication Optimisation or Pharmacological Interventions on Quantitative Measures of Cognitive Function i	3
Treatment of Bullous Pemphigoid in People Aged 80 Years and Older: A Systematic Review of the Literature	3
Non-Steroidal Anti-Inflammatory Drugs and Risk of Acute Kidney Injury and Hyperkalemia in Older Adults: A Retrospective Cohort Study and External Validation of a Clinical Risk Model	3
Incident Functional Limitations Among Community-Dwelling Adults Using Opioids: A Retrospective Cohort Study Using a Propensity Analysis with the Health and Retirement Study	3
Pain Management in Older Adults with Chronic Wounds	3
Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing	3
Management of Older Adults with Mantle Cell Lymphoma	3
The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation	3
Prevalence of Drug–Drug Interactions in Older Community-Dwelling Individuals: A Systematic Review and Meta-analysis	3
Medication Complexity Among Older Adults with HF: How Can We Assess Better?	3
Trends, Patterns and Associated User Characteristics of Antidepressant Prescriptions in Older Adults: A Nationwide Descriptive Cohort Study in Denmark	3
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders	3
Clinical Considerations for Insulin Therapy in Older Adults with Type 1 Diabetes	3
Menopausal Hormone Therapy in Older Women: Examining the Current Balance of Evidence	3
Nurses’, Pharmacists’ and Family Physicians’ Perceptions of Psychotropic Medication Monitoring in Australian Long-Term Care Facilities: A Qualitative Framework Analysis	3