OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Headache and Pain is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
CGRP-dependent sensitization of PKC-δ positive neurons in central amygdala mediates chronic migraine	473
Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition	234
Two-year effectiveness of erenumab in resistant chronic migraine: a prospective real-world analysis	149
Functionality, satisfaction, and global impression of change with ubrogepant for the acute treatment of migraine in triptan insufficient responders: a post hoc analysis of the ACHIEVE I and ACHIEVE II	108
Structured headache services as the solution to the ill-health burden of headache: 1. Rationale and description	103
Real-World experience of interictal burden and treatment in migraine: a qualitative interview study	101
Premonitory symptoms in migraine: a systematic review and meta-analysis of observational studies reporting prevalence or relative frequency	87
Psychological predictors of negative treatment outcome with Erenumab in chronic migraine: data from an open label long-term prospective study	82
Real-world impact of fremanezumab on migraine symptoms and resource utilization in the United States	73
The relationship between headache-attributed disability and lost productivity: 2. Empirical evidence from population-based studies in nine disparate countries	67
Differences in gray matter volume in episodic migraine patients with and without prior diagnosis or clinical care: a cross-sectional study	63
Patient-reported outcomes, health-related quality of life, and acute medication use in patients with a ≥ 75% response to eptinezumab: subgroup pooled analysis of the PROMISE trials	59
Efficacy of erenumab and factors predicting response after 3 months in treatment resistant chronic migraine: a clinical service evaluation	57
Identifying genetic variants for age of migraine onset in a Han Chinese population in Taiwan	57
Using natural language processing to automatically classify written self-reported narratives by patients with migraine or cluster headache	55
Pre-pregnancy migraine diagnosis, medication use, and spontaneous abortion: a prospective cohort study	54
Characteristics of N400 component elicited in patients who have migraine with aura	51
Visual stimulation and frequency of focal neurological symptoms engage distinctive neurocognitive resources in migraine with aura patients: a study of resting-state functional networks	49
Debate: Are cluster headache and migraine distinct headache disorders?	48
Measuring interictal burden among people affected by migraine: a descriptive survey study	48
Diagnostic criteria for acute headache attributed to ischemic stroke and for sentinel headache before ischemic stroke	47
Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients	46
CGRP and PACAP-38 play an important role in diagnosing pediatric migraine	45
Trigeminal ganglion itself can be a viable target to manage trigeminal neuralgia	45
Abnormalities in resting-state EEG microstates are a vulnerability marker of migraine	43

Age- and frequency-dependent changes in dynamic contrast perception in visual snow syndrome	42
Primary headaches during the COVID-19 lockdown in Germany: analysis of data from 2325 patients using an electronic headache diary	41
Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine	40
Similarities and differences between SUNCT and SUNA: a cross-sectional, multicentre study of 76 patients in China	39
One-quarter of individuals with weekly headache have never consulted a medical doctor: a Danish nationwide cross-sectional survey	39
A real-world study of acute and preventive medication use, adherence, and persistence in patients prescribed fremanezumab in the United States	37
Hypoperfusion in nucleus accumbens in chronic migraine using 3D pseudo-continuous arterial spin labeling imaging MRI	36
Efficacy and safety of erenumab in Japanese migraine patients with prior preventive treatment failure or concomitant preventive treatment: subgroup analyses of a phase 3, randomized trial	36
Real-world long-term efficacy and safety of erenumab in adults with chronic migraine: a 52-week, single-center, prospective, observational study	35
Total tenderness score and pressure pain thresholds in persistent post-traumatic headache attributed to mild traumatic brain injury	34
Swiss QUality of life and healthcare impact Assessment in a Real-world Erenumab treated migraine population (SQUARE study): interim results	34
A close association of freedom from pain, migraine-related functional disability, and other outcomes: results of a post hoc analysis of randomized lasmiditan studies SAMURAI and SPARTAN	33
Correction to: Manual joint mobilisation techniques, supervised physical activity, psychological treatment, acupuncture and patient education for patients with tension-type headache. A systematic revi	32
Gamma-aminobutyric acid and glutamate/glutamine levels in the dentate nucleus and periaqueductal gray with episodic and chronic migraine: a proton magnetic resonance spectroscopy study	32
Migraine epidemiology and comorbidities in Southern Israel: a clinical database study in a universal health coverage setting	32
Which is the best transcranial direct current stimulation protocol for migraine prevention? A systematic review and critical appraisal of randomized controlled trials	32
Attenuated alpha oscillation and hyperresponsiveness reveals impaired perceptual learning in migraineurs	32
Burden of migraine and unmet needs from the patients’ perspective: a survey across 11 specialized headache clinics in Korea	31
Inflammatory complications of CGRP monoclonal antibodies: a case series	30
Real-world evidence data on the monoclonal antibody erenumab in migraine prevention: perspectives of treating physicians in Germany	29
Intracranial pressure directly predicts headache morbidity in idiopathic intracranial hypertension	29
Activation of CamKIIα expressing neurons on ventrolateral periaqueductal gray improves behavioral hypersensitivity and thalamic discharge in a trigeminal neuralgia rat model	28
A phase 3, randomised, placebo-controlled study of erenumab for the prevention of chronic migraine in patients from Asia: the DRAGON study	28
Long term safety, tolerability, and efficacy of intracutaneous zolmitriptan (M207) in the acute treatment of migraine	28
Correction: Efficacy and safety of fremanezumab in clinical trial participants aged ≥60 years with episodic or chronic migraine: pooled results from 3 randomized, double-blind, placebo-controlled phas	28
HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain	27
Cerebral blood flow alterations in migraine patients with and without aura: An arterial spin labeling study	27
HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism	26
Altered effective connectivity in migraine patients during emotional stimuli: a multi-frequency magnetoencephalography study	26
Sphingosine-1 phosphate receptor 1 contributes to central sensitization in recurrent nitroglycerin-induced chronic migraine model	26
Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance	26
Osmophobia in primary headache patients: associated symptoms and response to preventive treatments	26
Manual joint mobilisation techniques, supervised physical activity, psychological treatment, acupuncture and patient education for patients with tension-type headache. A systematic review and meta-ana	26
Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy	25
Development and validation of a novel model for characterizing migraine outcomes within real-world data	25
The headache registry of the German Migraine and Headache Society (DMKG): baseline data of the first 1,351 patients	25
Unilateral facial injection of Botulinum neurotoxin A attenuates bilateral trigeminal neuropathic pain and anxiety-like behaviors through inhibition of TLR2-mediated neuroinflammation in mice	24
Eptinezumab treatment initiated during a migraine attack is associated with meaningful improvement in patient-reported outcome measures: secondary results from the randomized controlled RELIEF study	24
Age-related differences in resting state functional connectivity in pediatric migraine	24
Tracking the evolution of non-headache symptoms through the migraine attack	24
Acute prolonged motor aura resembling ischemic stroke after COVID − 19 vaccination (CoronaVac): the first case report	24
Reduction in acute migraine-specific and non-specific medication use in patients treated with erenumab: post-hoc analyses of episodic and chronic migraine clinical trials	24
De novo headache in ischemic stroke patients treated with thrombectomy: a prospective study	24
Cardiovascular outcomes in adults with migraine treated with eptinezumab for migraine prevention: pooled data from four randomized, double-blind, placebo-controlled studies	23
Regional homogeneity alterations in multi-frequency bands in tension-type headache: a resting-state fMRI study	23
Increased risk of all-cause, Alzheimer’s, and vascular dementia in adults with migraine in Korea: a population-based cohort study	23
Effectiveness and acceptability of noninvasive brain and nerve stimulation techniques for migraine prophylaxis: a network meta-analysis of randomized controlled trials	23
Microvascular decompression in trigeminal neuralgia - a prospective study of 115 patients	23
Pre-attack and pre-episode symptoms in cluster headache: a multicenter cross-sectional study of 327 Chinese patients	23
Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank	23

Correction: Burden of tension-type headache in the Middle East and North Africa region, 1990-2019