International Journal of Molecular Medicine

Papers
(The TQCC of International Journal of Molecular Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Pyroptosis in gastric mucosal injury‑related diseases (Review)89
Effects of sesamin on the chemosensitivity, invasiveness and immune evasion mechanism of human lung adenocarcinoma87
New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)73
miR‑4730 suppresses the progression of liver cancer by targeting the high mobility group A1 pathway63
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states61
[Retracted] TGF‑β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis59
[Retracted] Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA‑124 and thereby upregulating STAT359
YWHAH‑driven autophagy via MAPK/ERK signaling enhances CRC cell migration and invasion55
Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms51
TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation51
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration48
[Retracted] Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway48
[Retracted] Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure47
Epstein‑Barr virus as a promoter of tumorigenesis in the tumor microenvironment of breast cancer (Review)46
Common methods in mitochondrial research (Review)44
Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia‑reperfusion injury44
Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)43
Targeting p38 MAPK signaling pathway:  Quercetin as a novel therapy for TMJ synovitis43
Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)42
NLRP3 inflammasome in health and disease (Review)41
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)40
Hydrogen sulfide attenuates cigarette smoke‑induced pyroptosis through the TLR4/NF‑κB signaling pathway39
Exosomes derived from human dermal fibroblasts protect against UVB‑induced skin photoaging39
Current strategies for nonalcoholic fatty liver disease treatment (Review)37
Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review)37
Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway36
Enocyanin promotes osteogenesis and bone regeneration by inhibiting MMP936
Takotsubo syndrome: Unraveling the mystery behind its triggers (Review)36
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.236
[Retracted] Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway36
Effects and potential mechanism of Ca2+/calmodulin‑dependent protein kinase II pathway inhibitor KN93 on the development of ovarian follicle35
Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review)35
Human umbilical cord mesenchymal stem cell‑derived exosomes improve ovarian function in natural aging by inhibiting apoptosis34
Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF33
MEIS1‑regulated miR‑488‑3p suppresses the malignant progression of laryngeal squamous cell carcinoma by targeting ACVR1C32
Association of endometriosis with cardiovascular disease: Genetic aspects (Review)32
Identification of novel molecules and pathways associated with fascin actin‑bundling protein 1 in laryngeal squamous cell carcinoma through comprehensive transcriptome analysis32
Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review)32
Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review)31
[Corrigendum] Μolecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance31
Apelin‑13 in the paraventricular nucleus (PVN) attenuates myocardial ischemia through V1a receptors in PVN/nucleus tractus solitarii (NTS) and GARγ2 in NTS29
Mechanisms of action of retinal microglia in diabetic retinopathy (Review)29
HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression28
[Retracted] Sirt1 inhibits HG‑induced endothelial injury: Role of Mff‑based mitochondrial fission and F‑actin homeostasis‑mediated cellular migration27
Predictive value of the sFlt‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)26
Current status of severe fever with thrombocytopenia syndrome in China (Review)26
Understanding the impact of mitochondrial DNA mutations on aging and carcinogenesis (Review)26
[Corrigendum] Pharmacokinetics and antitumor efficacy of DSPE‑PEG2000 polymeric liposomes loaded with quercetin and temozolomide: Analysis of their effectiveness in enhancing the chemosensitization of26
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 ‘cytokine storm’26
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease25
[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues24
Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy24
From banked human cord blood to induced pluripotent stem cells: New opportunities and promise in induced pluripotent stem cell banking (Review)23
Upregulation of MTHFD2 is associated with PD‑L1 activation in bladder cancer via the PI3K/AKT pathway23
Protective effect of exercise on metabolic dysfunction‑associated fatty liver disease: Potential epigenetic mechanisms (Review)23
Free fatty acids induce coronary microvascular dysfunction via inhibition of the AMPK/KLF2/eNOS signaling pathway23
Multifaceted regulation and functions of 53BP1 in NHEJ‑mediated DSB repair (Review)21
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ321
[Corrigendum] A potential therapeutic effect of CYP2C8 overexpression on anti‑TNF‑α activity20
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway20
Vitamin D affects antiphospholipid syndrome by regulating T cells (Review)19
[Retracted] Isopsoralen‑mediated suppression of bone marrow adiposity and attenuation of the adipogenic commitment of bone marrow‑derived mesenchymal stem cells19
[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway19
[Retracted] Knockdown of SNHG16 suppresses the proliferation and induces the apoptosis of leukemia cells via miR‑193a‑5p/CDK819
Deciphering the emerging landscape of HOX genes in cardiovascular biology, atherosclerosis and beyond (Review)18
[Expression of Concern] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy18
Short‑chain fatty acids regulate hepatocellular carcinoma progression: A metabolic perspective on tumor immunity (Review)18
m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review)18
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction18
Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors18
Lymphangiogenesis: A new strategy for heart disease treatment (Review)18
Elimination of intracellular Ca2+ overload by BAPTA‑AM liposome nanoparticles: A promising treatment for acute pancreatitis17
Molecular pathways associated with oxidative stress and their potential applications in radiotherapy (Review)17
[Corrigendum] miR‑490‑5p regulates the proliferation, migration, invasion and epithelial‑mesenchymal transition of pharyngolaryngeal cancer cells by targeting mitogen‑activated protein kinase kinase k17
A comprehensive review on pain: Model, target, therapy, and prospect (Review)17
Importance of STAT3 signaling in preeclampsia (Review)17
Quercetin ameliorates senescence and promotes osteogenesis of BMSCs by suppressing the repetitive element‑triggered RNA sensing pathway17
Study on the in vitro changes of human bone marrow‑related mesenchymal stem cells17
Exploring the association between melatonin and nicotine dependence (Review)17
HIF‑1α: Its notable role in the maintenance of oxygen, bone and iron homeostasis (Review)17
GW8510 alleviates muscle atrophy and skeletal muscle dysfunction in mice through AMPK/PGC1α signaling16
[Corrigendum] Knockdown of HOXA10 reverses the multidrug resistance of human chronic mylogenous leukemia K562/ADM cells by downregulating P‑gp and MRP‑116
Inflammation and coagulation abnormalities via the activation of the HMGB1‑RAGE/NF‑κB and F2/Rho pathways in lung injury induced by acute hypoxia16
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy16
New insights into the role of ubiquitination in angiogenesis (Review)16
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy16
Emerging role of small RNAs in inflammatory bowel disease and associated colorectal cancer (Review)16
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines16
Beclin‑1 exerts protective effects against cerebral ischemia‑reperfusion injury by promoting DNA damage repair through a non‑autophagy‑dependent regulatory mechanism15
Ferroptosis and head and neck cancer: Mechanisms and therapeutic perspectives (Review)15
The gut‑skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review)15
Dysregulated programmed cell death of intestinal epithelial cells in ulcerative colitis: Molecular mechanisms and novel therapeutic interventions (Review)15
In situ hybridization for the assessment of urokinase plasminogen activator and plasminogen activator inhibitor type‑1 in formalin‑fixed paraffin‑embedded breast cancer specimens15
ZNF667 facilitates angiogenesis after myocardial ischemia through transcriptional regulation of VASH1 and Wnt signaling pathway15
Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome15
[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes15
[Retracted] Hedgehog signaling is involved in the BMP9‑induced osteogenic differentiation of mesenchymal stem cells15
Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling14
Copper supplementation alleviates hypoxia‑induced ferroptosis and oxidative stress in neuronal cells14
Unveiling the multifaceted role of adropin in various diseases (Review)14
Current updates regarding biogenesis, functions and dysregulation of microRNAs in cancer: Innovative approaches for detection using CRISPR/Cas13‑based platforms (Review)14
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice14
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer13
Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol‑induced cell death and heart failure13
Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)13
Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review)13
PANoptosis: Novel insight into regulated cell death and its potential role in cardiovascular diseases (Review)13
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways13
lncRNA DHFRL1‑4 knockdown attenuates cerebral ischemia/reperfusion injury by upregulating the levels of angiogenesis‑related genes13
MicroRNA‑885‑5p regulates cell cycle progression in liver cancer cells13
Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)13
Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer13
Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases (Review)12
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis12
[Corrigendum] SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling12
[Corrigendum] miR‑29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC‑1α signaling: Implications for age‑related hearing loss12
SDF2 promotes glioma progression via GRP78‑mediated ERAD and copper homeostasis disruption12
Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases (Review)12
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review)12
Repositioning of aripiprazole, an anti‑psychotic drug, to sensitize the chemotherapy of pancreatic cancer12
Gossypin induces apoptosis and autophagy via the MAPK/JNK pathway in HT‑29 human colorectal cancer cells12
[Retracted] Altered expression of miR‑92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis12
New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis12
Insight into microbial extracellular vesicles as key communication materials and their clinical implications for lung cancer (Review)12
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy12
Circular RNAs and the regulation of gene expression in diabetic nephropathy (Review)12
[Retracted] Antagonist targeting miR‑106b‑5p attenuates acute renal injury by regulating renal function, apoptosis and autophagy via the upregulation of TCF412
Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)11
Mitochondrial dysfunction in perimenopausal mood disorders: From hormonal shifts to neuroenergetic failure (Review)11
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway11
miR‑27b‑3p modulates CD4+CD39+ Tregs to drive immune‑mediated intervertebraldisc degeneration11
[Retracted] Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway11
The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)11
Changes in the endoplasmic reticulum‑mitochondria communication in dermal fibroblasts from early‑stage bipolar disorder patients: Skin‑brain axis as a new route to understand the pathophysiology of me11
[Retracted] miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab1011
Silencing of circular RNA‑ZYG11B exerts a neuroprotective effect against retinal neurodegeneration11
Stanniocalcin‑1 suppresses TGF‑β‑induced mitochondrial dysfunction and cellular fibrosis in human renal proximal tubular cells11
Multidisciplinary approaches to study anaemia with special mention on aplastic anaemia (Review)11
[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP211
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD411
[Corrigendum] Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling10
Role of the TGF‑β/Smad signaling pathway in the transition from acute kidney injury to chronic kidney disease (Review)10
Advances in the study of regulators of ferroptosis in head and neck squamous cell carcinoma (Review)10
Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)10
13‑cis‑retinoic acid inhibits the self‑renewal, migration, invasion and adhesion of cholangiocarcinoma cells10
Insights on the differences between two‑ and three‑dimensional culture systems in tumor models (Review)10
Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)10
Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)10
[Corrigendum] Bax inhibitor‑1 suppresses early brain injury following experimental subarachnoid hemorrhage in rats10
Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding10
Research progress on mesenchymal stem cell‑derived exosomes in the treatment of osteoporosis induced by knee osteoarthritis (Review)10
Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)10
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling9
Expansion of B10 cells in vitro: Pathways, techniques and applications in transplantation (Review)9
Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia9
A novel and promising therapeutic approach for treating pancreatic cancer: Nectin‑4‑targeted antibody‑drug conjugates alone or combined with autophagy inhibitors9
Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 39
Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)9
Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)9
[Corrigendum] Morroniside protects SK‑N‑SH human neuroblastoma cells against H2O2‑induced damage9
Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells9
Dual roles of oxostephanine as an Aurora kinase inhibitor and angiogenesis suppressor9
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis9
Metformin reverses oxidative stress‑induced mitochondrial dysfunction in pre‑osteoblasts via the EGFR/GSK‑3β/calcium pathway9
Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)9
Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway9
Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)9
Multi‑omics analysis of right ventricles in rat models of pulmonary arterial hypertension: Consideration of mitochondrial biogenesis by chrysin9
Topical calcineurin and mammalian target of rapamycin inhibitors in inflammatory dermatoses: Current challenges and nanotechnology‑based prospects (Review)9
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