International Journal of Molecular Medicine

Article	Citations
Effects of sesamin on the chemosensitivity, invasiveness and immune evasion mechanism of human lung adenocarcinoma	113
Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)	111
New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)	87
The roles and heterogeneity of CD8 + T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)	81
Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)	80
[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4	79
[Retracted] TGF‑β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis	76
[Retracted] Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway	75
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states	75
Targeting p38 MAPK signaling pathway:  Quercetin as a novel therapy for TMJ synovitis	70
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration	68
[Retracted] Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure	67
miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways	61
Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)	58
Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis	55
ETS‑1/ETS‑2 transcription factors in CVD (Review)	55
Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review)	52
Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms	52
Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)	51
Common methods in mitochondrial research (Review)	50
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)	48
Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms	48
Exosomes derived from human dermal fibroblasts protect against UVB‑induced skin photoaging	48
NLRP3 inflammasome in health and disease (Review)	48
Epstein‑Barr virus as a promoter of tumorigenesis in the tumor microenvironment of breast cancer (Review)	48

YWHAH‑driven autophagy via MAPK/ERK signaling enhances CRC cell migration and invasion	46
Pyroptosis in gastric mucosal injury‑related diseases (Review)	45
Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury	45
[Retracted] Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway	45
Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)	45
Enocyanin promotes osteogenesis and bone regeneration by inhibiting MMP9	44
circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance	42
Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway	42
Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review)	41
Takotsubo syndrome: Unraveling the mystery behind its triggers (Review)	37
Association of endometriosis with cardiovascular disease: Genetic aspects (Review)	37
[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis	37
Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF	36
miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis	35
[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert	35
Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)	35
Human umbilical cord mesenchymal stem cell‑derived exosomes improve ovarian function in natural aging by inhibiting apoptosis	33
Current strategies for nonalcoholic fatty liver disease treatment (Review)	32
Effects and potential mechanism of Ca2+/calmodulin‑dependent protein kinase II pathway inhibitor KN93 on the development of ovarian follicle	31
MEIS1‑regulated miR‑488‑3p suppresses the malignant progression of laryngeal squamous cell carcinoma by targeting ACVR1C	30
Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review)	30
Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)	28
[Corrigendum] Μolecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance	28
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 ‘cytokine storm’	28
Free fatty acids induce coronary microvascular dysfunction via inhibition of the AMPK/KLF2/eNOS signaling pathway	28
Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy	28
HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression	27
From banked human cord blood to induced pluripotent stem cells: New opportunities and promise in induced pluripotent stem cell banking (Review)	26
[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues	26
[Corrigendum] Pharmacokinetics and antitumor efficacy of DSPE‑PEG2000 polymeric liposomes loaded with quercetin and temozolomide: Analysis of their effectiveness in enhancing the chemosensitization of	26
[Retracted] Sirt1 inhibits HG‑induced endothelial injury: Role of Mff‑based mitochondrial fission and F‑actin homeostasis‑mediated cellular migration	26
Understanding the impact of mitochondrial DNA mutations on aging and carcinogenesis (Review)	24
Research progress in single‑cell omics technologies for kidney disease (Review)	24
Identification of novel molecules and pathways associated with fascin actin‑bundling protein 1 in laryngeal squamous cell carcinoma through comprehensive transcriptome analysis	24
Apelin‑13 in the paraventricular nucleus (PVN) attenuates myocardial ischemia through V1a receptors in PVN/nucleus tractus solitarii (NTS) and GARγ2 in NTS	24
Protective effect of exercise on metabolic dysfunction‑associated fatty liver disease: Potential epigenetic mechanisms (Review)	23
Upregulation of MTHFD2 is associated with PD‑L1 activation in bladder cancer via the PI3K/AKT pathway	23
Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)	22
Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review)	22
Current status of severe fever with thrombocytopenia syndrome in China (Review)	22
Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis	22
Mechanisms of action of retinal microglia in diabetic retinopathy (Review)	22
Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)	22
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3	21
[Retracted] Isopsoralen‑mediated suppression of bone marrow adiposity and attenuation of the adipogenic commitment of bone marrow‑derived mesenchymal stem cells	21
Vitamin D affects antiphospholipid syndrome by regulating T cells (Review)	21
Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review)	21
[Corrigendum] A potential therapeutic effect of CYP2C8 overexpression on anti‑TNF‑α activity	21
IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)	21
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway	21

Predictive value of the sFlt‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)	21
Rab27: Molecular switch of tumor exosome secretion (Review)	21
RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)	20
[Retracted] Knockdown of SNHG16 suppresses the proliferation and induces the apoptosis of leukemia cells via miR‑193a‑5p/CDK8	20
[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development	20
[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway	19
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction	19
Exploring the association between melatonin and nicotine dependence (Review)	19
[Corrigendum]	19
[Expression of Concern] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy	19
Deciphering the emerging landscape of HOX genes in cardiovascular biology, atherosclerosis and beyond (Review)	18
Lymphangiogenesis: A new strategy for heart disease treatment (Review)	18
Short‑chain fatty acids regulate hepatocellular carcinoma progression: A metabolic perspective on tumor immunity (Review)	18
HIF‑1α: Its notable role in the maintenance of oxygen, bone and iron homeostasis (Review)	18
Importance of STAT3 signaling in preeclampsia (Review)	18
Quercetin ameliorates senescence and promotes osteogenesis of BMSCs by suppressing the repetitive element‑triggered RNA sensing pathway	18
Elimination of intracellular Ca2+ overload by BAPTA‑AM liposome nanoparticles: A promising treatment for acute pancreatitis	18
m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review)	18
GW8510 alleviates muscle atrophy and skeletal muscle dysfunction in mice through AMPK/PGC1α signaling	17
Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes	17
[Corrigendum] Knockdown of HOXA10 reverses the multidrug resistance of human chronic mylogenous leukemia K562/ADM cells by downregulating P‑gp and MRP‑1	17
A comprehensive review on pain: Model, target, therapy, and prospect (Review)	17
4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation	17
Study on the in vitro changes of human bone marrow‑related mesenchymal stem cells	16
[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells	16
Inflammation and coagulation abnormalities via the activation of the HMGB1‑RAGE/NF‑κB and F2/Rho pathways in lung injury induced by acute hypoxia	16
New insights into the role of ubiquitination in angiogenesis (Review)	16
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy	16
Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)	16
ZNF667 facilitates angiogenesis after myocardial ischemia through transcriptional regulation of VASH1 and Wnt signaling pathway	16
Emerging role of small RNAs in inflammatory bowel disease and associated colorectal cancer (Review)	16
[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress	16
The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)	16
Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)	15
The gut‑skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review)	15
Oridonin ameliorates ulcerative colitis by regulating the PI3K/AKT/mTOR signaling pathway to activate autophagy	15
[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes	15
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines	15
MicroRNA‑885‑5p regulates cell cycle progression in liver cancer cells	15
[Retracted] Hedgehog signaling is involved in the BMP9‑induced osteogenic differentiation of mesenchymal stem cells	15
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy	15
Ferroptosis and head and neck cancer: Mechanisms and therapeutic perspectives (Review)	14
Copper supplementation alleviates hypoxia‑induced ferroptosis and oxidative stress in neuronal cells	14
Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells	14
Unveiling the multifaceted role of adropin in various diseases (Review)	14
Current updates regarding biogenesis, functions and dysregulation of microRNAs in cancer: Innovative approaches for detection using CRISPR/Cas13‑based platforms (Review)	14
Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)	14
Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling	14
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer	14
Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol‑induced cell death and heart failure	13
Dysregulated programmed cell death of intestinal epithelial cells in ulcerative colitis: Molecular mechanisms and novel therapeutic interventions (Review)	13
Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)	13
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis	13
Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer	13
Circular RNAs and the regulation of gene expression in diabetic nephropathy (Review)	13
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy	13
[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation	13
Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review)	13
Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)	13
Repositioning of aripiprazole, an anti‑psychotic drug, to sensitize the chemotherapy of pancreatic cancer	13
[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway	13
[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16	13
Endothelial UNC5B regulates blood‑retinal barrier homeostasis	13
Gossypin induces apoptosis and autophagy via the MAPK/JNK pathway in HT‑29 human colorectal cancer cells	13
Myokines in exercise‑mediated bone homeostasis: Molecular signaling mechanisms and therapeutic implications for bone disorders (Review)	13
PANoptosis: Novel insight into regulated cell death and its potential role in cardiovascular diseases (Review)	13
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review)	13
Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases (Review)	13
Insight into microbial extracellular vesicles as key communication materials and their clinical implications for lung cancer (Review)	13
[Retracted] Antagonist targeting miR‑106b‑5p attenuates acute renal injury by regulating renal function, apoptosis and autophagy via the upregulation of TCF4	12
Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)	12
[Retracted] miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10	12
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways	12
Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases (Review)	12
Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome	12
[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway	12
[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy	12
[Retracted] Altered expression of miR‑92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis	12
Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)	12
Multidisciplinary approaches to study anaemia with special mention on aplastic anaemia (Review)	12

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)	12
[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2	12
Changes in the endoplasmic reticulum‑mitochondria communication in dermal fibroblasts from early‑stage bipolar disorder patients: Skin‑brain axis as a new route to understand the pathophysiology of me	12
New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis	12
Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)	12
Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)	11
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway	11
SDF2 promotes glioma progression via GRP78‑mediated ERAD and copper homeostasis disruption	11
Role of cuproptosis in digestive system tumors (Review)	11
Mitochondrial dysfunction in perimenopausal mood disorders: From hormonal shifts to neuroenergetic failure (Review)	11
Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)	11
[Corrigendum] Bax inhibitor‑1 suppresses early brain injury following experimental subarachnoid hemorrhage in rats	11
miR‑27b‑3p modulates CD4+CD39+ Tregs to drive immune‑mediated intervertebraldisc degeneration	11
Primary cilia dysfunction: A critical driver of metabolic diseases (Review)	11
[Corrigendum] Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling	11
Metformin reverses oxidative stress‑induced mitochondrial dysfunction in pre‑osteoblasts via the EGFR/GSK‑3β/calcium pathway	10
[Retracted] Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway	10
13‑cis‑retinoic acid inhibits the self‑renewal, migration, invasion and adhesion of cholangiocarcinoma cells	10
Role of the TGF‑β/Smad signaling pathway in the transition from acute kidney injury to chronic kidney disease (Review)	10
Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)	10
Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)	10
[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis	10
Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)	10
Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)	10
Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)	10
Topical calcineurin and mammalian target of rapamycin inhibitors in inflammatory dermatoses: Current challenges and nanotechnology‑based prospects (Review)	10
Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding	10
CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis	10
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis	9
Advances in the study of regulators of ferroptosis in head and neck squamous cell carcinoma (Review)	9
Insights on the differences between two‑ and three‑dimensional culture systems in tumor models (Review)	9
[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liri	9
Research progress in myocardial function and diseases related to muscarinic acetylcholine receptor (Review)	9
A novel and promising therapeutic approach for treating pancreatic cancer: Nectin‑4‑targeted antibody‑drug conjugates alone or combined with autophagy inhibitors	9
Role of MEX3A in tumorigenesis: Mechanisms, tumor‑specific effects and therapeutic implications (Review)	9
A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)	9
Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)	9
Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)	9
ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)	9
[Corrigendum] Morroniside protects SK‑N‑SH human neuroblastoma cells against H2O2‑induced damage	9
FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)	9
Role of solute carrier transporters in ovarian cancer (Review)	9
Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway	9
FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1	9
Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)	9
Research progress on mesenchymal stem cell‑derived exosomes in the treatment of osteoporosis induced by knee osteoarthritis (Review)	9
Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)	9
Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)	9
Dual roles of oxostephanine as an Aurora kinase inhibitor and angiogenesis suppressor	9
Paeoniflorigenone inhibits ovarian cancer metastasis through targeting the MUC1/Wnt/β‑catenin pathway	9
Expansion of B10 cells in vitro: Pathways, techniques and applications in transplantation (Review)	9