OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Molecular Medicine is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Pyroptosis in gastric mucosal injury‑related diseases (Review)	106
Effects of sesamin on the chemosensitivity, invasiveness and immune evasion mechanism of human lung adenocarcinoma	101
Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review)	82
Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia‑reperfusion injury	75
Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)	74
Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)	68
The roles and heterogeneity of CD8 ⁺ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)	68
New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)	68
[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4	64
Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms	63
[Retracted] TGF‑β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis	63
[Retracted] Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway	58
Epstein‑Barr virus as a promoter of tumorigenesis in the tumor microenvironment of breast cancer (Review)	54
[Retracted] Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure	53
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states	53
Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)	53
YWHAH‑driven autophagy via MAPK/ERK signaling enhances CRC cell migration and invasion	49
miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways	48
Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)	47
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)	47
ETS‑1/ETS‑2 transcription factors in CVD (Review)	45
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration	45
NLRP3 inflammasome in health and disease (Review)	44
Common methods in mitochondrial research (Review)	44
Targeting p38 MAPK signaling pathway: Quercetin as a novel therapy for TMJ synovitis	43

Effects and potential mechanism of Ca²⁺/calmodulin‑dependent protein kinase II pathway inhibitor KN93 on the development of ovarian follicle	43
Exosomes derived from human dermal fibroblasts protect against UVB‑induced skin photoaging	43
Takotsubo syndrome: Unraveling the mystery behind its triggers (Review)	42
Total flavonoids of Rhizoma Drynariae enhances CD31^hiEmcn^hi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF	42
Human umbilical cord mesenchymal stem cell‑derived exosomes improve ovarian function in natural aging by inhibiting apoptosis	41
[Retracted] Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway	41
Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway	41
Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review)	39
[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis	38
Association of endometriosis with cardiovascular disease: Genetic aspects (Review)	37
Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway	36
Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review)	36
circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance	36
Enocyanin promotes osteogenesis and bone regeneration by inhibiting MMP9	36
Current strategies for nonalcoholic fatty liver disease treatment (Review)	33
MEIS1‑regulated miR‑488‑3p suppresses the malignant progression of laryngeal squamous cell carcinoma by targeting ACVR1C	32
Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)	32
[Corrigendum] Μolecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance	30
Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy	29
Free fatty acids induce coronary microvascular dysfunction via inhibition of the AMPK/KLF2/eNOS signaling pathway	29
[Retracted] Sirt1 inhibits HG‑induced endothelial injury: Role of Mff‑based mitochondrial fission and F‑actin homeostasis‑mediated cellular migration	28
HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression	28
[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues	27
[Corrigendum] Pharmacokinetics and antitumor efficacy of DSPE‑PEG2000 polymeric liposomes loaded with quercetin and temozolomide: Analysis of their effectiveness in enhancing the chemosensitization of	27
From banked human cord blood to induced pluripotent stem cells: New opportunities and promise in induced pluripotent stem cell banking (Review)	27
Identification of novel molecules and pathways associated with fascin actin‑bundling protein 1 in laryngeal squamous cell carcinoma through comprehensive transcriptome analysis	26
Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)	25
Multifaceted regulation and functions of 53BP1 in NHEJ‑mediated DSB repair (Review)	25
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 ‘cytokine storm’	25
Understanding the impact of mitochondrial DNA mutations on aging and carcinogenesis (Review)	24
Cholesterol metabolism and cancer: Molecular mechanisms, immune regulation and an epidemiological perspective (Review)	24
Current status of severe fever with thrombocytopenia syndrome in China (Review)	24
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway	24
Research progress in single‑cell omics technologies for kidney disease (Review)	23
Apelin‑13 in the paraventricular nucleus (PVN) attenuates myocardial ischemia through V1a receptors in PVN/nucleus tractus solitarii (NTS) and GARγ2 in NTS	23
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3	22
Mechanisms of action of retinal microglia in diabetic retinopathy (Review)	22
Predictive value of the sFlt‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)	22
Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)	22
Protective effect of exercise on metabolic dysfunction‑associated fatty liver disease: Potential epigenetic mechanisms (Review)	21
Upregulation of MTHFD2 is associated with PD‑L1 activation in bladder cancer via the PI3K/AKT pathway	21
[Retracted] Isopsoralen‑mediated suppression of bone marrow adiposity and attenuation of the adipogenic commitment of bone marrow‑derived mesenchymal stem cells	20
[Expression of Concern] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy	20
IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)	20
Vitamin D affects antiphospholipid syndrome by regulating T cells (Review)	20
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction	20
[Corrigendum] A potential therapeutic effect of CYP2C8 overexpression on anti‑TNF‑α activity	20
Deciphering the emerging landscape of HOX genes in cardiovascular biology, atherosclerosis and beyond (Review)	19
[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway	19
[Retracted] Knockdown of SNHG16 suppresses the proliferation and induces the apoptosis of leukemia cells via miR‑193a‑5p/CDK8	19

m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review)	19
[Corrigendum]	19
HIF‑1α: Its notable role in the maintenance of oxygen, bone and iron homeostasis (Review)	19
Short‑chain fatty acids regulate hepatocellular carcinoma progression: A metabolic perspective on tumor immunity (Review)	19
Quercetin ameliorates senescence and promotes osteogenesis of BMSCs by suppressing the repetitive element‑triggered RNA sensing pathway	19
Exploring the association between melatonin and nicotine dependence (Review)	19
RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)	18
A comprehensive review on pain: Model, target, therapy, and prospect (Review)	18
Emerging role of small RNAs in inflammatory bowel disease and associated colorectal cancer (Review)	18
Lymphangiogenesis: A new strategy for heart disease treatment (Review)	18
Importance of STAT3 signaling in preeclampsia (Review)	18
ZNF667 facilitates angiogenesis after myocardial ischemia through transcriptional regulation of VASH1 and Wnt signaling pathway	18
Elimination of intracellular Ca²⁺ overload by BAPTA‑AM liposome nanoparticles: A promising treatment for acute pancreatitis	18
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines	18
GW8510 alleviates muscle atrophy and skeletal muscle dysfunction in mice through AMPK/PGC1α signaling	17
4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation	17
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy	17
The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)	17
New insights into the role of ubiquitination in angiogenesis (Review)	17
[Corrigendum] Knockdown of HOXA10 reverses the multidrug resistance of human chronic mylogenous leukemia K562/ADM cells by downregulating P‑gp and MRP‑1	17
Study on the in vitro changes of human bone marrow‑related mesenchymal stem cells	16
Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes	16
Inflammation and coagulation abnormalities via the activation of the HMGB1‑RAGE/NF‑κB and F2/Rho pathways in lung injury induced by acute hypoxia	16
Unveiling the multifaceted role of adropin in various diseases (Review)	15
Ferroptosis and head and neck cancer: Mechanisms and therapeutic perspectives (Review)	15
Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)	15
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy	15
Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling	15
[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2 cardiac myocytes	15
[Retracted] Hedgehog signaling is involved in the BMP9‑induced osteogenic differentiation of mesenchymal stem cells	15
Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)	15
The gut‑skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review)	15
Copper supplementation alleviates hypoxia‑induced ferroptosis and oxidative stress in neuronal cells	15
Dysregulated programmed cell death of intestinal epithelial cells in ulcerative colitis: Molecular mechanisms and novel therapeutic interventions (Review)	14
Current updates regarding biogenesis, functions and dysregulation of microRNAs in cancer: Innovative approaches for detection using CRISPR/Cas13‑based platforms (Review)	14
Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells	14
PANoptosis: Novel insight into regulated cell death and its potential role in cardiovascular diseases (Review)	14
Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review)	14
MicroRNA‑885‑5p regulates cell cycle progression in liver cancer cells	14
Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)	14
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer	14
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways	13
Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol‑induced cell death and heart failure	13
Circular RNAs and the regulation of gene expression in diabetic nephropathy (Review)	13
Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)	13
Gossypin induces apoptosis and autophagy via the MAPK/JNK pathway in HT‑29 human colorectal cancer cells	13
Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)	13
[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway	13
lncRNA DHFRL1‑4 knockdown attenuates cerebral ischemia/reperfusion injury by upregulating the levels of angiogenesis‑related genes	13
[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation	13
Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer	13
Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases (Review)	13
New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis	12
Endothelial UNC5B regulates blood‑retinal barrier homeostasis	12
Insight into microbial extracellular vesicles as key communication materials and their clinical implications for lung cancer (Review)	12
Role of cuproptosis in digestive system tumors (Review)	12
Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases (Review)	12
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review)	12
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy	12
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis	12
Multidisciplinary approaches to study anaemia with special mention on aplastic anaemia (Review)	12
[Retracted] miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10	12
Repositioning of aripiprazole, an anti‑psychotic drug, to sensitize the chemotherapy of pancreatic cancer	12
[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16	12
SDF2 promotes glioma progression via GRP78‑mediated ERAD and copper homeostasis disruption	12
[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2	12
[Retracted] Altered expression of miR‑92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis	11
The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)	11
Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)	11
Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)	11
Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)	11
13‑cis‑retinoic acid inhibits the self‑renewal, migration, invasion and adhesion of cholangiocarcinoma cells	11
Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)	11
Mitochondrial dysfunction in perimenopausal mood disorders: From hormonal shifts to neuroenergetic failure (Review)	11
[Retracted] Antagonist targeting miR‑106b‑5p attenuates acute renal injury by regulating renal function, apoptosis and autophagy via the upregulation of TCF4	11
Silencing of circular RNA‑ZYG11B exerts a neuroprotective effect against retinal neurodegeneration	11
[Corrigendum] Bax inhibitor‑1 suppresses early brain injury following experimental subarachnoid hemorrhage in rats	11
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway	11
Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding	11
[Corrigendum] Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling	11

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy	11
Stanniocalcin‑1 suppresses TGF‑β‑induced mitochondrial dysfunction and cellular fibrosis in human renal proximal tubular cells	11
Changes in the endoplasmic reticulum‑mitochondria communication in dermal fibroblasts from early‑stage bipolar disorder patients: Skin‑brain axis as a new route to understand the pathophysiology of me	11
[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway	11
[Retracted] Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway	11
Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)	11
Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)	11
Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)	11
miR‑27b‑3p modulates CD4+CD39+ Tregs to drive immune‑mediated intervertebraldisc degeneration	11
Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)	10
A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)	10
Advances in the study of regulators of ferroptosis in head and neck squamous cell carcinoma (Review)	10
Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 3	10
[Corrigendum] Morroniside protects SK‑N‑SH human neuroblastoma cells against H₂O₂‑induced damage	10
ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)	10
[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis	10
Insights on the differences between two‑ and three‑dimensional culture systems in tumor models (Review)	10
Research progress on mesenchymal stem cell‑derived exosomes in the treatment of osteoporosis induced by knee osteoarthritis (Review)	10
Expansion of B10 cells in vitro: Pathways, techniques and applications in transplantation (Review)	10
Metformin reverses oxidative stress‑induced mitochondrial dysfunction in pre‑osteoblasts via the EGFR/GSK‑3β/calcium pathway	10
Topical calcineurin and mammalian target of rapamycin inhibitors in inflammatory dermatoses: Current challenges and nanotechnology‑based prospects (Review)	10
Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)	10
Role of the TGF‑β/Smad signaling pathway in the transition from acute kidney injury to chronic kidney disease (Review)	10
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis	10
Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)	10
CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway	9
Role of solute carrier transporters in ovarian cancer (Review)	9
Dual roles of oxostephanine as an Aurora kinase inhibitor and angiogenesis suppressor	9
A novel and promising therapeutic approach for treating pancreatic cancer: Nectin‑4‑targeted antibody‑drug conjugates alone or combined with autophagy inhibitors	9
Tanshinone IIA protects against chronic obstructive pulmonary disease via exosome‑shuttled miR‑486‑5p	9
Casticin suppresses RANKL‑induced osteoclastogenesis and prevents ovariectomy‑induced bone loss by regulating the AKT/ERK and NF‑κB signaling pathways	9
Clinical updates of B‑cell maturation antigen‑targeted therapy in multiple myeloma (MM) and relapsed/refractory MM (Review)	9
Effects of DNA methylation and its application in inflammatory bowel disease (Review)	9
Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway	9
FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)	9
Paeoniflorigenone inhibits ovarian cancer metastasis through targeting the MUC1/Wnt/β‑catenin pathway	9
[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liri	9
Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway	9
[Retracted]	9
Role of MEX3A in tumorigenesis: Mechanisms, tumor‑specific effects and therapeutic implications (Review)	9
Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)	9
Research progress in myocardial function and diseases related to muscarinic acetylcholine receptor (Review)	9
Compound Kushen injection attenuates angiotensin II‑mediated heart failure by inhibiting the PI3K/Akt pathway	9
Kirenol relieves rheumatoid arthritis by targeting the TWEAK/Fn14 pathway	9
Exosome‑mediated crosstalk between the cardiovascular and musculoskeletal systems: Mechanisms and therapeutic potential (Review)	8
FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages	8
Copper homeostasis and cuproptosis in Alzheimer's disease (Review)	8
Animal models accurately representing acute liver failure (Review)	8
Egr‑1 promotes the proliferation and migration of vascular smooth muscle cells by transcriptionally activating Egr‑2 in arteriovenous fistulas	8
Low‑intensity pulsed ultrasound accelerates diabetic wound healing by ADSC‑derived exosomes via promoting the uptake of exosomes and enhancing angiogenesis	8
Exosome‑encapsulated miR‑26a attenuates aldosterone‑induced tubulointerstitial fibrosis by inhibiting the CTGF/SMAD3 signaling pathway	8
TREM2, a critical activator of pyroptosis, mediates the anti‑tumor effects of piceatannol in uveal melanoma cells via caspase 3/GSDME pathwayTREM2, a critical activator of pyroptosis, mediates the ant	8
Role of non‑coding RNAs as biomarkers and the application of omics technologies in Alzheimer's disease (Review)	8
Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)	8
[Retracted] TRIM16 suppresses the progression of prostate tumors by inhibiting the Snail signaling pathway	8
Developments in the connection between epithelial‑mesenchymal transition and endoplasmic reticulum stress (Review)	8
[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration	8
Multiple roles and mechanisms of MUC6 in cancer (Review)	8
ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade	8
[Retracted] Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway	8
Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1	8
Dulaglutide markedly prevents peritoneal fibrosis in a rodent model of chronic kidney disease: Insights into the pathogenesis	8
Inflammatory signaling pathways in the treatment of Alzheimer's disease with inhibitors, natural products and metabolites (Review)	8
[Corrigendum] miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease	8
METTL14‑mediated RNA methylation in digestive system tumors	8
Curculigoside mitigates dextran sulfate sodium‑induced colitis by activation of KEAP1‑NRF2 interaction to inhibit oxidative damage and autophagy of intestinal epithelium barrier	8
Recent insights and perspectives into the role of the miRNA‑29 family in innate immunity (Review)	8
MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)	7
Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)	7
Prucalopride might improve intestinal motility by promoting the regeneration of the enteric nervous system in diabetic rats	7
RKIP suppresses the influenza A virus‑induced airway inflammatory response via the ERK/MAPK pathway	7
Ultrasound‑targeted microbubble destruction technology delivering β‑klotho to the heart enhances FGF21 sensitivity and attenuates heart remodeling post‑myocardial infarction	7
Nitric oxide‑mediated S‑Nitrosylation contributes to signaling transduction in human physiological and pathological status (Review)	7
Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)	7
Emerging threat of environmental microplastics: A comprehensive analysis of hepatic metabolic dysregulation and hepatocellular damage (Review)	7
[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of	7
Circular RNAs in coronary heart disease: From molecular mechanism to promising clinical application (Review)	7
[Corrigendum] Effects of miR‑340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines	7
[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway	7
Obesity in reproduction: Mechanisms from fertilization to post‑uterine development (Review)	7
Multi‑omics reveal neutrophil heterogeneity in sepsis (Review)	7
USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)	7
mROS‑calcium feedback loop promotes lethal ventricular arrhythmias and sudden cardiac death in early myocardial ischemia	7
[Retracted] Activation of the δ‑opioid receptor inhibits serum deprivation‑induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway	7
Role of the m⁶A demethylase ALKBH5 in gastrointestinal tract cancer (Review)	7
[Retracted] KIF22 promotes bladder cancer progression by activating the expression of CDCA3	7
Post‑translational modifications in diabetic kidney disease (Review)	7
Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2	7
Role of itaconate in intestinal disease (Review)	7
Tribbles pseudokinase 3 drives cancer stemness in oral squamous cell carcinoma cells by supporting the expression levels of SOX2 and EGFR	6
Role and mechanisms of cuproptosis in the pathogenesis of Wilson's disease (Review)	6
Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer	6
Role of DNA methylation transferase in urinary system diseases: From basic to clinical perspectives (Review)	6
Selective inhibition of JNK located on mitochondria protects against mitochondrial dysfunction and cell death caused by endoplasmic reticulum stress in mice with LPS‑induced ALI/ARDS	6
Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)	6