OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Molecular Medicine is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Pyroptosis in gastric mucosal injury‑related diseases (Review)	362
miR‑4730 suppresses the progression of liver cancer by targeting the high mobility group A1 pathway	79
Common methods in mitochondrial research (Review)	78
Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia‑reperfusion injury	66
Effects of sesamin on the chemosensitivity, invasiveness and immune evasion mechanism of human lung adenocarcinoma	64
Research progress, challenges and perspectives of phospholipids metabolism in the LXR‑LPCAT3 signaling pathway and its relation to NAFLD (Review)	60
NLRP3 inflammasome in health and disease (Review)	54
Exosomes derived from human dermal fibroblasts protect against UVB‑induced skin photoaging	52
Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms	52
New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)	49
Hydrogen sulfide attenuates cigarette smoke‑induced pyroptosis through the TLR4/NF‑κB signaling pathway	46
Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states	45
Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)	43
[Retracted] Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA‑124 and thereby upregulating STAT3	42
[Retracted] TGF‑β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis	42
[Retracted] Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway	42
TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation	41
Secretome of EMSCs neutralizes LPS‑induced acute lung injury via aerosol administration	41
[Retracted] Effect of apelin on the cardiac hemodynamics in hypertensive rats with heart failure	39
Takotsubo syndrome: Unraveling the mystery behind its triggers (Review)	38
Epstein‑Barr virus as a promoter of tumorigenesis in the tumor microenvironment of breast cancer (Review)	38
Metformin inhibits pulmonary artery smooth muscle cell proliferation by upregulating p21 via NONRATT015587.2	36
Enocyanin promotes osteogenesis and bone regeneration by inhibiting MMP9	35
Effects and potential mechanism of Ca²⁺/calmodulin‑dependent protein kinase II pathway inhibitor KN93 on the development of ovarian follicle	35
Molecular modelling of novel ADCY3 variant predicts a molecular target for tackling obesity	35

[Retracted] Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway	34
Total flavonoids of Rhizoma Drynariae enhances CD31^hiEmcn^hi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF	34
Mitochondrial dysfunction in chronic neuroinflammatory diseases (Review)	34
Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway	33
Human umbilical cord mesenchymal stem cell‑derived exosomes improve ovarian function in natural aging by inhibiting apoptosis	33
Association of endometriosis with cardiovascular disease: Genetic aspects (Review)	33
Current strategies for nonalcoholic fatty liver disease treatment (Review)	32
Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review)	32
Upregulation of MTHFD2 is associated with PD‑L1 activation in bladder cancer via the PI3K/AKT pathway	31
[Corrigendum] Pharmacokinetics and antitumor efficacy of DSPE‑PEG2000 polymeric liposomes loaded with quercetin and temozolomide: Analysis of their effectiveness in enhancing the chemosensitization of	30
Identification of novel molecules and pathways associated with fascin actin‑bundling protein 1 in laryngeal squamous cell carcinoma through comprehensive transcriptome analysis	29
HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple‑negative breast cancer metastasis via the inhibition of CXCR4 expression	28
Free fatty acids induce coronary microvascular dysfunction via inhibition of the AMPK/KLF2/eNOS signaling pathway	28
Attenuation of hepatic ischemia‑reperfusion injury by adipose stem cell‑derived exosome treatment via ERK1/2 and GSK‑3β signaling pathways	27
MEIS1‑regulated miR‑488‑3p suppresses the malignant progression of laryngeal squamous cell carcinoma by targeting ACVR1C	26
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 ‘cytokine storm’	26
[Corrigendum] Μolecular impact of bone morphogenetic protein 7, on lung cancer cells and its clinical significance	26
Mechanisms of action of retinal microglia in diabetic retinopathy (Review)	25
[Retracted] Sirt1 inhibits HG‑induced endothelial injury: Role of Mff‑based mitochondrial fission and F‑actin homeostasis‑mediated cellular migration	25
Understanding the impact of mitochondrial DNA mutations on aging and carcinogenesis (Review)	24
Protective effect of exercise on metabolic dysfunction‑associated fatty liver disease: Potential epigenetic mechanisms (Review)	23
Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease	23
Multifaceted regulation and functions of 53BP1 in NHEJ‑mediated DSB repair (Review)	23
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR‑18a‑3p/Gsdmd pathway	23
Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3	23
Current status of severe fever with thrombocytopenia syndrome in China (Review)	23
Apelin‑13 in the paraventricular nucleus (PVN) attenuates myocardial ischemia through V1a receptors in PVN/nucleus tractus solitarii (NTS) and GARγ2 in NTS	23
From banked human cord blood to induced pluripotent stem cells: New opportunities and promise in induced pluripotent stem cell banking (Review)	22
Vitamin D affects antiphospholipid syndrome by regulating T cells (Review)	22
[Corrigendum] A potential therapeutic effect of CYP2C8 overexpression on anti‑TNF‑α activity	22
Predictive value of the sFlt‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)	22
[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway	22
[Retracted] Knockdown of SNHG16 suppresses the proliferation and induces the apoptosis of leukemia cells via miR‑193a‑5p/CDK8	21
[Retracted] Isopsoralen‑mediated suppression of bone marrow adiposity and attenuation of the adipogenic commitment of bone marrow‑derived mesenchymal stem cells	21
Quercetin ameliorates senescence and promotes osteogenesis of BMSCs by suppressing the repetitive element‑triggered RNA sensing pathway	20
KIF22 promotes bladder cancer progression by activating the expression of CDCA3	20
Deciphering the emerging landscape of HOX genes in cardiovascular biology, atherosclerosis and beyond (Review)	20
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction	20
m6A modification of non‑coding RNA: Mechanisms, functions and potential values in human diseases (Review)	19
The DR1‑CSE/H₂S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice	19
Lymphangiogenesis: A new strategy for heart disease treatment (Review)	19
Molecular pathways associated with oxidative stress and their potential applications in radiotherapy (Review)	18
EGCG prevents pressure overload‑induced myocardial remodeling by downregulating overexpression of HDAC5 in mice	18
[Expression of Concern] S100A8‑targeting siRNA enhances arsenic trioxide‑induced myeloid leukemia cell death by down‑regulating autophagy	18
Exploring the association between melatonin and nicotine dependence (Review)	18
Elimination of intracellular Ca²⁺ overload by BAPTA‑AM liposome nanoparticles: A promising treatment for acute pancreatitis	18
HIF‑1α: Its notable role in the maintenance of oxygen, bone and iron homeostasis (Review)	17
[Corrigendum] miR‑490‑5p regulates the proliferation, migration, invasion and epithelial‑mesenchymal transition of pharyngolaryngeal cancer cells by targeting mitogen‑activated protein kinase kinase k	17
Inflammation and coagulation abnormalities via the activation of the HMGB1‑RAGE/NF‑κB and F2/Rho pathways in lung injury induced by acute hypoxia	17
Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors	17

Study on the in vitro changes of human bone marrow‑related mesenchymal stem cells	17
[Corrigendum] Knockdown of HOXA10 reverses the multidrug resistance of human chronic mylogenous leukemia K562/ADM cells by downregulating P‑gp and MRP‑1	17
Importance of STAT3 signaling in preeclampsia (Review)	17
Short‑chain fatty acids regulate hepatocellular carcinoma progression: A metabolic perspective on tumor immunity (Review)	17
The gut‑skin axis: Emerging insights in understanding and treating skin diseases through gut microbiome modulation (Review)	17
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines	16
New insights into the role of ubiquitination in angiogenesis (Review)	16
ZNF667 facilitates angiogenesis after myocardial ischemia through transcriptional regulation of VASH1 and Wnt signaling pathway	16
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy	16
Emerging role of small RNAs in inflammatory bowel disease and associated colorectal cancer (Review)	16
In situ hybridization for the assessment of urokinase plasminogen activator and plasminogen activator inhibitor type‑1 in formalin‑fixed paraffin‑embedded breast cancer specimens	15
[Retracted] Hedgehog signaling is involved in the BMP9‑induced osteogenic differentiation of mesenchymal stem cells	15
[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2 cardiac myocytes	15
MicroRNA‑885‑5p regulates cell cycle progression in liver cancer cells	15
Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome	15
GW8510 alleviates muscle atrophy and skeletal muscle dysfunction in mice through AMPK/PGC1α signaling	15
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis	15
PANoptosis: Novel insight into regulated cell death and its potential role in cardiovascular diseases (Review)	14
Unveiling the multifaceted role of adropin in various diseases (Review)	14
Current updates regarding biogenesis, functions and dysregulation of microRNAs in cancer: Innovative approaches for detection using CRISPR/Cas13‑based platforms (Review)	14
Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)	14
Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling	14
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice	14
Metformin prevents the onset and progression of intervertebral disc degeneration: New insights and potential mechanisms (Review)	14
Beclin‑1 exerts protective effects against cerebral ischemia‑reperfusion injury by promoting DNA damage repair through a non‑autophagy‑dependent regulatory mechanism	13
lncRNA DHFRL1‑4 knockdown attenuates cerebral ischemia/reperfusion injury by upregulating the levels of angiogenesis‑related genes	13
Ablation of CXCR4 expression in cardiomyocytes exacerbates isoproterenol‑induced cell death and heart failure	13
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer	13
Ferroptosis and head and neck cancer: Mechanisms and therapeutic perspectives (Review)	13
TNF‑α induces premature senescence in tendon stem cells via the NF‑κB and p53/p21/cyclin E/CDK2 signaling pathways	13
Copper supplementation alleviates hypoxia‑induced ferroptosis and oxidative stress in neuronal cells	13
Circular RNAs and the regulation of gene expression in diabetic nephropathy (Review)	13
Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases (Review)	13
Clarifying the molecular mechanism of tomentosin‑induced antiproliferative and proapoptotic effects in human multiple myeloma via gene expression profile and genetic interaction network analysis	12
Molecular mechanisms and clinicopathological characteristics of inhibin βA in thyroid cancer metastasis	12
Insight into microbial extracellular vesicles as key communication materials and their clinical implications for lung cancer (Review)	12
Role of lysine lactylation in neoplastic and inflammatory pulmonary diseases (Review)	12
[Corrigendum] miR‑29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC‑1α signaling: Implications for age‑related hearing loss	12
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy	12
Spotlight on HOX cluster‑embedded antisense lncRNAs in cardiovascular diseases (Review)	12
New insight for SS‑31 in treating diabetic cardiomyopathy: Activation of mitoGPX4 and alleviation of mitochondria‑dependent ferroptosis	12
[Retracted] Altered expression of miR‑92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis	12
Repositioning of aripiprazole, an anti‑psychotic drug, to sensitize the chemotherapy of pancreatic cancer	12
Gossypin induces apoptosis and autophagy via the MAPK/JNK pathway in HT‑29 human colorectal cancer cells	12
[Corrigendum] SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling	12
Silencing of circular RNA‑ZYG11B exerts a neuroprotective effect against retinal neurodegeneration	11
miR‑27b‑3p modulates CD4+CD39+ Tregs to drive immune‑mediated intervertebraldisc degeneration	11
[Corrigendum] Bax inhibitor‑1 suppresses early brain injury following experimental subarachnoid hemorrhage in rats	11
[Retracted] Ginsenoside Rg3 ameliorates acute pancreatitis by activating the NRF2/HO‑1‑mediated ferroptosis pathway	11
[Retracted] Antagonist targeting miR‑106b‑5p attenuates acute renal injury by regulating renal function, apoptosis and autophagy via the upregulation of TCF4	11
Multidisciplinary approaches to study anaemia with special mention on aplastic anaemia (Review)	11
Changes in the endoplasmic reticulum‑mitochondria communication in dermal fibroblasts from early‑stage bipolar disorder patients: Skin‑brain axis as a new route to understand the pathophysiology of me	11
Topical calcineurin and mammalian target of rapamycin inhibitors in inflammatory dermatoses: Current challenges and nanotechnology‑based prospects (Review)	11
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4	11
Stanniocalcin‑1 suppresses TGF‑β‑induced mitochondrial dysfunction and cellular fibrosis in human renal proximal tubular cells	11
[Retracted] miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10	11
SDF2 promotes glioma progression via GRP78‑mediated ERAD and copper homeostasis disruption	11
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway	11
Role of dendritic cell‑derived exosomes in allergic rhinitis (Review)	10
Insights on the differences between two‑ and three‑dimensional culture systems in tumor models (Review)	10
Dual roles of oxostephanine as an Aurora kinase inhibitor and angiogenesis suppressor	10
13‑cis‑retinoic acid inhibits the self‑renewal, migration, invasion and adhesion of cholangiocarcinoma cells	10
Research progress on mesenchymal stem cell‑derived exosomes in the treatment of osteoporosis induced by knee osteoarthritis (Review)	10
Epitranscriptomics of cardiovascular diseases (Review)	10
2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling	10
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis	10
Multi‑omics analysis of right ventricles in rat models of pulmonary arterial hypertension: Consideration of mitochondrial biogenesis by chrysin	10
Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding	10
Role of the TGF‑β/Smad signaling pathway in the transition from acute kidney injury to chronic kidney disease (Review)	10
Advances in the study of regulators of ferroptosis in head and neck squamous cell carcinoma (Review)	10
Metformin reverses oxidative stress‑induced mitochondrial dysfunction in pre‑osteoblasts via the EGFR/GSK‑3β/calcium pathway	10
[Corrigendum] Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling	10
Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 3	10
A novel and promising therapeutic approach for treating pancreatic cancer: Nectin‑4‑targeted antibody‑drug conjugates alone or combined with autophagy inhibitors	9
Role of solute carrier transporters in ovarian cancer (Review)	9
Role of MEX3A in tumorigenesis: Mechanisms, tumor‑specific effects and therapeutic implications (Review)	9
Tanshinone IIA protects against chronic obstructive pulmonary disease via exosome‑shuttled miR‑486‑5p	9
Compound Kushen injection attenuates angiotensin II‑mediated heart failure by inhibiting the PI3K/Akt pathway	9
Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells	9
Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia	9

Expansion of B10 cells in vitro: Pathways, techniques and applications in transplantation (Review)	9
Effects of DNA methylation and its application in inflammatory bowel disease (Review)	9
Research progress in myocardial function and diseases related to muscarinic acetylcholine receptor (Review)	9
[Corrigendum] Morroniside protects SK‑N‑SH human neuroblastoma cells against H₂O₂‑induced damage	9
Paeoniflorigenone inhibits ovarian cancer metastasis through targeting the MUC1/Wnt/β‑catenin pathway	8
Exosome‑mediated crosstalk between the cardiovascular and musculoskeletal systems: Mechanisms and therapeutic potential (Review)	8
Copper homeostasis and cuproptosis in Alzheimer's disease (Review)	8
Exosome‑encapsulated miR‑26a attenuates aldosterone‑induced tubulointerstitial fibrosis by inhibiting the CTGF/SMAD3 signaling pathway	8
Multiple roles and mechanisms of MUC6 in cancer (Review)	8
Curculigoside mitigates dextran sulfate sodium‑induced colitis by activation of KEAP1‑NRF2 interaction to inhibit oxidative damage and autophagy of intestinal epithelium barrier	8
METTL14‑mediated RNA methylation in digestive system tumors	8
[Retracted] Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway	8
Recent insights and perspectives into the role of the miRNA‑29 family in innate immunity (Review)	8
Casticin suppresses RANKL‑induced osteoclastogenesis and prevents ovariectomy‑induced bone loss by regulating the AKT/ERK and NF‑κB signaling pathways	8
ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade	8
Role of non‑coding RNAs as biomarkers and the application of omics technologies in Alzheimer's disease (Review)	8
Hyperthermia accelerates neuronal loss differently between the hippocampal CA1 and CA2/3 through different HIF‑1α expression after transient ischemia in gerbils	8
Circular RNAs in coronary heart disease: From molecular mechanism to promising clinical application (Review)	8
CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway	8
Activin A rescues preterm brain injury through a novel Noggin/BMP4/Id2 signaling pathway	8
TREM2, a critical activator of pyroptosis, mediates the anti‑tumor effects of piceatannol in uveal melanoma cells via caspase 3/GSDME pathwayTREM2, a critical activator of pyroptosis, mediates the ant	8
Clinical updates of B‑cell maturation antigen‑targeted therapy in multiple myeloma (MM) and relapsed/refractory MM (Review)	8
Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1	8
Low‑intensity pulsed ultrasound accelerates diabetic wound healing by ADSC‑derived exosomes via promoting the uptake of exosomes and enhancing angiogenesis	8
Efficacy of the use of mefenamic acid combined with standard medical care vs. standard medical care alone for the treatment of COVID‑19: A randomized double‑blind placebo‑controlled trial	8
Silencing of ISLR inhibits tumour progression and glycolysis by inactivating the IL‑6/JAK/STAT3 pathway in non‑small cell lung cancer	8
Kirenol relieves rheumatoid arthritis by targeting the TWEAK/Fn14 pathway	8
Developments in the connection between epithelial‑mesenchymal transition and endoplasmic reticulum stress (Review)	7
[Retracted] Activation of the δ‑opioid receptor inhibits serum deprivation‑induced apoptosis of human liver cells via the activation of PKC and the mitochondrial pathway	7
[Corrigendum] miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease	7
[Retracted] TRIM16 suppresses the progression of prostate tumors by inhibiting the Snail signaling pathway	7
Egr‑1 promotes the proliferation and migration of vascular smooth muscle cells by transcriptionally activating Egr‑2 in arteriovenous fistulas	7
[Retracted] KIF22 promotes bladder cancer progression by activating the expression of CDCA3	7
Dulaglutide markedly prevents peritoneal fibrosis in a rodent model of chronic kidney disease: Insights into the pathogenesis	7
mROS‑calcium feedback loop promotes lethal ventricular arrhythmias and sudden cardiac death in early myocardial ischemia	7
Sildenafil protects against pulmonary hypertension induced by hypoxia in neonatal rats via activation of PPARγ‑mediated downregulation of TRPC	7
Role of vitamins in the development and treatment of osteoporosis (Review)	7
RKIP suppresses the influenza A virus‑induced airway inflammatory response via the ERK/MAPK pathway	7
Inflammatory signaling pathways in the treatment of Alzheimer's disease with inhibitors, natural products and metabolites (Review)	7
Prucalopride might improve intestinal motility by promoting the regeneration of the enteric nervous system in diabetic rats	7
[Corrigendum] Effects of miR‑340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines	7
Advances of exosome regulating‑FXR to repair inflammatory bowel disease (Review)	7
Role of the m⁶A demethylase ALKBH5 in gastrointestinal tract cancer (Review)	6
TP53 mutations in cancer: Molecular features and therapeutic opportunities (Review)	6
Selective inhibition of JNK located on mitochondria protects against mitochondrial dysfunction and cell death caused by endoplasmic reticulum stress in mice with LPS‑induced ALI/ARDS	6
[Retracted] MicroRNA‑432 inhibits the aggressiveness of glioblastoma multiforme by directly targeting IGF‑1R	6
Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway	6
Role of DNA methylation transferase in urinary system diseases: From basic to clinical perspectives (Review)	6
Potential and challenges of utilizing exosomes in osteoarthritis therapy (Review)	6
Obesity in reproduction: Mechanisms from fertilization to post‑uterine development (Review)	6
Nitric oxide‑mediated S‑Nitrosylation contributes to signaling transduction in human physiological and pathological status (Review)	6
[Retracted] Circular RNA CSNK1G1 promotes the progression of osteoarthritis by targeting the miR‑4428/FUT2 axis	6
Gab2 promotes the growth of colorectal cancer by regulating the M2 polarization of tumor‑associated macrophages	6
Role and mechanisms of cuproptosis in the pathogenesis of Wilson's disease (Review)	6
The role of astrocyte metabolic reprogramming in ischemic stroke (Review)	6
Iron metabolism and the tumor microenvironment: A new perspective on cancer intervention and therapy (Review)	6
Role of ferroptosis in the pathogenesis and as a therapeutic target of inflammatory bowel disease (Review)	6
2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines	6
Emerging threat of environmental microplastics: A comprehensive analysis of hepatic metabolic dysregulation and hepatocellular damage (Review)	6
Tribbles pseudokinase 3 drives cancer stemness in oral squamous cell carcinoma cells by supporting the expression levels of SOX2 and EGFR	6
Starvation mediates pancreatic cancer cell sensitivity to ferroptosis via ERK1/2, JNK and changes in the cell mesenchymal state	6
Unveiling the role of RhoA and ferroptosis in vascular permeability: Implications for osteoarthritis	6
Sophoricoside attenuates autoimmune‑mediated liver injury through the regulation of oxidative stress and the NF‑κB signaling pathway	6
Bmi1 regulates neural differentiation of mesenchymal stem cells through the Wnt3a‑RhoA signaling pathway to repair ischemic brain injury in rats	6
Ultrasound‑targeted microbubble destruction technology delivering β‑klotho to the heart enhances FGF21 sensitivity and attenuates heart remodeling post‑myocardial infarction	6
Extracellular vesicles from tonsil‑derived mesenchymal stromal cells show anti‑tumor effect via miR‑199a‑3p	6
Role of GADD45A in myocardial ischemia/reperfusion through mediation of the JNK/p38 MAPK and STAT3/VEGF pathways	5
Talin‑1 interaction network in cellular mechanotransduction (Review)	5
Liriodendrin alleviates myocardial ischemia‑reperfusion injury via partially attenuating apoptosis, inflammation and mitochondria damage in rats	5
Senolytic combination of dasatinib and quercetin protects against diabetic kidney disease by activating autophagy to alleviate podocyte dedifferentiation via the Notch pathway	5
High‑dose X‑ray irradiation induces NETosis via the eCIRP/TREM‑1 axis in mouse neutrophils	5
[Retracted] Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar‑to‑ductal metaplasia through PI3K/Akt/IKK	5
Osteosarcoma stem cells resist chemotherapy by maintaining mitochondrial dynamic stability via DRP1	5
Cell death‑related molecules and targets in the progression of urolithiasis (Review)	5
Methylation‑sensitive restriction enzyme‑droplet digital PCR assay for the one‑step highly sensitive analysis of DNA methylation hotspots	5
Vestibular dysfunction leads to cognitive impairments: State of knowledge in the field and clinical perspectives (Review)	5
SENP1 promotes p27kip1 nuclear export though enhanced SUMOylation in cholangiocarcinoma leading to increased cell proliferation and chemoresistance	5
RBM8A promotes gastric cancer progression by binding with UPF3B to induce BBC3 mRNA degradation	5
Role of cellular senescence in hepatic diseases (Review)	5
[Retracted] MicroRNA‑7 functions as a tumor‑suppressor gene by regulating ILF2 in pancreatic carcinoma	5
[Retracted] Jumonji AT‑rich interactive domain 1B overexpression is associated with the development and progression of glioma	5
CD150‑dependent activation of EBV‑transformed B cells induces the differentiation of peripheral blood monocytes via the secretion of multiple cytokines	5
[Retracted] lncRNA KCNQ1OT1 promotes proliferation and invasion of glioma cells by targeting the miR‑375/YAP pathway	5
Resveratrol ameliorates nutritional steatohepatitis through the mmu‑miR‑599/PXR pathway	5
Linking microRNA to metabolic reprogramming and gut microbiota in the pathogenesis of colorectal cancer (Review)	5
[Retracted] MicroRNA‑15a‑5p‑targeting oncogene YAP1 inhibits cell viability and induces cell apoptosis in cervical cancer cells	5
Navigating paediatric virology through the COVID‑19 era (Review)	5
Vaginal microbiome and preterm birth: Composition, mechanisms and microbiota‑directed therapies (Review)	5
Exhaustion‑like dysfunction of T and NKT cells in an X‑linked severe combined immunodeficiency patient with maternal engraftment by single‑cell analysis	5
How lactate and lactylation shape the immunity system in atherosclerosis (Review)	5
Curcumin and Wnt/β‑catenin signaling in exudative age‑related macular degeneration (Review)	5
A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cell‑surface proteins on target cells	4
Lycorine upregulates the expression of RMB10, promotes apoptosis and inhibits the proliferation and migration of cervical cancer cells	4
Public neoantigens in breast cancer immunotherapy (Review)	4
Calycosin attenuates mitochondrial damage and pyroptosis in heart failure via the Nrf2/ROS/TXNIP pathway	4