OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Gene Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
COVID‐19: Virology, biology and novel laboratory diagnosis	211
OMICRON: Virology, immunopathogenesis, and laboratory diagnosis	33
Long non‐coding RNAs: Promising new targets in pulmonary fibrosis	25
U7 snRNA: A tool for gene therapy	24
Synovial mesenchymal stem cell‐derived extracellular vesicles containing microRN555A‐26a‐5p ameliorate cartilage damage of osteoarthritis	23
Circ‐PRMT5 promotes breast cancer by the miR‐509‐3p/TCF7L2 axis activating the PI3K/AKT pathway	22
Gene therapy in cancer	22
CRISPR‐Cas9 screening identified lethal genes enriched in necroptosis pathway and of prognosis significance in osteosarcoma	19
SNHG16/miR‐485‐5p/BMP7 axis modulates osteogenic differentiation of human bone marrow‐derived mesenchymal stem cells	19
lncRNA OIP5‐AS1 knockdown or miR‐223 overexpression can alleviate LPS‐induced ALI/ARDS by interfering with miR‐223/NLRP3‐mediated pyroptosis	18
MicroRNA‐145‐5p targeting of TRIM2 mediates the apoptosis of retinal ganglion cells via the PI3K/AKT signaling pathway in glaucoma	18
Circular RNA circ_0001588 sponges miR‐211‐5p to facilitate the progression of glioblastoma via up‐regulating YY1 expression	18
Circulating miR‐181a and miR‐223 expression with the potential value of biomarkers for the diagnosis of systemic lupus erythematosus and predicting lupus nephritis	18
RETRACTED: Long non‐coding RNA KCNQ1OT1 promotes the progression of gastric cancer via the miR‐145‐5p/ARF6 axis	18
lncRNA MCM3AP‐AS1 inhibits the progression of colorectal cancer via the miR‐19a‐3p/FOXF2 axis	17
PD‐L1 versus tumor mutation burden: Which is the better immunotherapy biomarker in advanced non‐small cell lung cancer?	17
Long non‐coding DANCR targets miR‐185‐5p to upregulate LIM and SH3 protein 1 promoting prostate cancer via the FAK/PI3K/AKT/GSK3β/snail pathway	17
Identification of the shared gene signatures and molecular pathways in systemic lupus erythematosus and diffuse large B‐cell lymphoma	17
EZH2 upregulates the expression of MAPK1 to promote intervertebral disc degeneration via suppression of miR‐129‐5p	16
Long non‐coding RNA SNHG8 promotes prostate cancer progression through repressing miR‐384 and up‐regulating HOXB7	16
Long non‐coding RNA ADAMTS9‐AS1 inhibits the progression of prostate cancer by modulating the miR‐142‐5p/CCND1 axis	16
Histidine‐enhanced gene delivery systems: The state of the art	15
Inhibition of hsa_circ_0003489 shifts balance from autophagy to apoptosis and sensitizes multiple myeloma cells to bortezomib via miR‐874‐3p/HDAC1 axis	15
Stromal cell‐derived factor‐1 promotes osteoblastic differentiation of human bone marrow mesenchymal stem cells via the lncRNA‐H19/miR‐214‐5p/BMP2 axis	14
An assessment of the analytical performance of non‐invasive prenatal testing (NIPT) in detecting sex chromosome aneuploidies: 34,717‐patient sample in a single prenatal diagnosis Centre in China	14

Bioinformatics‐based analysis of programmed cell death pathway and key prognostic genes in gastric cancer: Implications for the development of therapeutics	14
STAT3 activates the transcription of lncRNA NR2F1‐AS1 to promote the progression of melanoma via regulating the miR‐493‐5p/GOLM1 axis	14
Circular RNA hsa_circ_0005397 promotes hepatocellular carcinoma progression by regulating the miR‐326/PDK2 axis	13
CircADAMTS6/miR‐431‐5p axis regulate interleukin‐1β induced chondrocyte apoptosis	13
CSRP3, p.Arg122*, is responsible for hypertrophic cardiomyopathy in a Chinese family	13
Long non‐coding RNA MCF2L‐AS1 promotes the aggressiveness of colorectal cancer by sponging miR‐874‐3p and thereby up‐regulating CCNE1	13
Rare genetic disorders: Beyond whole‐exome sequencing	13
Circular RNA ITCH attenuates the progression of nasopharyngeal carcinoma by inducing PTEN upregulation via miR‐214	13
Inhibition of circ_0081234 reduces prostate cancer tumor growth and metastasis via the miR‐1/MAP 3 K1 axis	13
LINC02288 promotes chondrocyte apoptosis and inflammation through miR‐374a‐3p targeting RTN3	13
Down‐regulation of circITCH promotes osteosarcoma development and resistance to doxorubicin via the miR‐524/RASSF6 axis	13
VEGF₁₆₅ gene‐modified human umbilical cord blood mesenchymal stem cells protect against acute liver failure in rats	13
Exosomes derived from bone marrow mesenchymal stem cells pretreated with decellularized extracellular matrix enhance the alleviation of osteoarthritis through miR‐3473b/phosphatase and tensin homolog	12
lncRNA MALAT1 promotes osteogenic differentiation through the miR‐217/AKT3 axis: A possible strategy to alleviate osteoporosis	12
YY1‐mediated up‐regulation of lncRNA LINC00466 facilitates glioma progression via miR‐508/CHEK1	12
The lncRNA MEG3/miR‐16‐5p/VGLL4 regulatory axis is involved in etoposide‐induced senescence of tumor cells	12
Circ_0006006 facilitates non‐small cell lung cancer progression by modulating miR‐924/SRSF7 axis	11
Long noncoding RNA SNHG9 facilitates growth of glioma stem‐like cells via miR‐326/SOX9 axis	11
A brief introduction of meta‐analyses in clinical practice and research	11
Design of a new cell penetrating peptide for DNA, siRNA and mRNA delivery	11
Circular RNA circ_0040823 inhibits the proliferation of acute myeloid leukemia cells and induces apoptosis by regulating miR‐516b/PTEN	11
Pharmacogenetic profiling of dihydropyrimidine dehydrogenase (DPYD) variants in the Indian population	11
Profiling of specific long non‐coding RNA signatures identifies ST8SIA6‐AS1 AS a novel target for breast cancer	11
Antibody‐dependent enhancement (ADE) of dengue virus: Identification of the key amino acid that is vital in DENV vaccine research	10
Homozygous missense variant in POPDC3 causes recessive limb‐girdle muscular dystrophy type 26	10
Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system	10
Prenatal diagnosis of 913 fetuses samples using copy number variation sequencing	10
CircVAPA exerts oncogenic property in non‐small cell lung cancer by the miR‐876‐5p/WNT5A axis	10
Circulating status of microRNAs 660‐5p and 210‐3p in breast cancer patients	10
LINC00852 is associated with poor prognosis in non‐small cell lung cancer patients and its inhibition suppresses cancer cell proliferation and chemoresistance via the hsa‐miR‐145‐5p/KLF4 axis	10
Fiber modifications enable fowl adenovirus 4 vectors to transduce human cells	10
Down‐regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR‐455‐5p	9
Location of a single histidine within peptide carriers increases mRNA delivery	9
PCSK9 genetic (rs11591147) and epigenetic (DNA methylation) modifications associated with PCSK9 expression and serum proteins in CAD patients	9
Hsa_circ_0040809 regulates colorectal cancer development by upregulating methyltransferase DNMT1 via targeting miR‐515‐5p	9
FN1 and cancer‐associated fibroblasts markers influence immune microenvironment in clear cell renal cell carcinoma	9
The lncRNA HOXA11‐AS acts as a tumor promoter in breast cancer through regulation of the miR‐125a‐5p/TMPRSS4 axis	9
Vitamin D receptor gene polymorphismTaqI(rs731236) and its association with the susceptibility to coronary artery disease among Pakistani population	9
Inhibition of lncRNA DCST1‐AS1 suppresses proliferation, migration and invasion of cervical cancer cells by increasing miR‐874‐3p expression	9
Extracellular vesicle‐packaged miR‐181c‐5p from epithelial ovarian cancer cells promotes M2 polarization of tumor‐associated macrophages via the KAT2B/HOXA10 axis	9
Hsa_circRNA_102229 facilitates the progression of triple‐negative breast cancer via regulating the miR‐152‐3p/PFTK1 pathway	9
Non‐coding RNAs are correlated to TGF‐β receptor type 2 in patients with colorectal cancer	8
Dysregulated cholesterol regulatory genes as a diagnostic biomarker for cancer	8
Genetic variation in catechol‐O‐methyltransferase is associated with individual differences in conditioned pain modulation in healthy subjects	8
Role of FTO gene polymorphisms in Wilms tumor predisposition: A five‐center case–control study	8
Molecular characterization of two Chinese pedigrees with maternally inherited hypertension	8
circANKRD28 inhibits cisplatin resistance in non‐small‐cell lung cancer through the miR‐221‐3p/SOCS3 axis	8
lncRNA ANRIL accelerates wound healing in diabetic foot ulcers via modulating HIF1A/VEGFA signaling through interacting with FUS	8
lncRNA FBXL19‐AS1 is a diagnosis biomarker for paediatric patients with acute myeloid leukemia	8
LINC00460 promotes pancreatic cancer progression by sponging miR‐491‐5p	8

hsa_circ_0001610 knockdown modulates miR‐646‐STAT3 axis to suppress endometrial carcinoma progression	8
The impact of certain genetic variants (single nucleotide polymorphisms) on incidence and severity of COVID‐19	8
Long non‐coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR‐326/PKM2 axis	8
The diagnostic significance of circulating lncRNA ADAMTS9‐AS2 tumor biomarker in non‐small cell lung cancer among the Egyptian population	8
LINC00958 promotes endometrial cancer cell proliferation and metastasis by regulating the miR‐145‐3p/TCF4 axis	8
Viral and non‐viral gene therapy using 3D (bio)printing	7
Propofol attenuates renal ischemia/reperfusion injury by regulating the MALAT1/miR‐126‐5p axis	7
Long non‐coding RNA SCARNA2 induces cutaneous squamous cell carcinoma progression via modulating miR‐342‐3p expression	7
PP7080 expedites the proliferation and migration of lung adenocarcinoma cells via sponging miR‐670‐3p and regulating UHRF1BP1	7
lncRNA IGF2‐AS promotes the osteogenic differentiation of bone marrow mesenchymal stem cells by sponging miR‐3,126‐5p to upregulate KLK4	7
Long noncoding RNA 02027 inhibits proliferation, migration and invasion of hepatocellular carcinoma via miR‐625‐3p/PDLIM5 pathway	7
Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR‐217	7
Tumor promoting long non‐coding RNA CASC15 affects HMGB2 expression by sponging miR‐582‐5p in colorectal cancer	7
miR‐4286 promotes prostate cancer progression by targeting the expression of SALL1	7
Successful liver transduction by re‐administration of different adeno‐associated virus vector serotypes in mice	7
Genetic risk score constructed from common genetic variants is associated with cardiovascular disease risk in type 2 diabetes mellitus	7
Linoleic‐acid‐substituted polyethylenimine to silence heat shock protein 90B1 (HSP90B1) to inhibit migration of breast cancer cells	6
Assessment of ADCY9 polymorphisms and colorectal cancer risk in the Chinese Han population	6
GSK484, an inhibitor of peptidyl arginine deiminase 4, increases the radiosensitivity of colorectal cancer and inhibits neutrophil extracellular traps	6
Circ_0072088 knockdown contributes to cisplatin sensitivity and inhibits tumor progression by miR‐944/LASP1 axis in non‐small cell lung cancer	6
Long noncoding RNA AC092155 facilitates osteogenic differentiation of adipose‐derived stem cells through the miR‐143‐3p/STMN1 axis	6
Application of CAR‐T cell technology in autoimmune diseases and human immunodeficiency virus infection treatment	6
Inhibition of the long non‐coding RNA UNC5B‐AS1/miR‐4455/RSPO4 axis reduces cervical cancer growth in vitro and in vivo	6
ANKRD37 inhibits trophoblast migration and invasion by regulating the NF‐κB pathway in preeclampsia	6
Copy number variation characterization and possible candidate genes in miscarriage and stillbirth by next‐generation sequencing analysis	6
Network pharmacology and bioinformatics analysis on the underlying mechanisms of baicalein against oral squamous cell carcinoma	6
Association of CLU gene polymorphism with Parkinson's disease in the Chinese Han population	6
Rabbit umbilical cord mesenchymal stem cells: A new option for tissue engineering	6
Association of IRGM gene promoter polymorphisms with hepatitis B virus infection	6
Silencing of circDPP4 suppresses cell progression of human prostate cancer and enhances docetaxel cytotoxicity through regulating the miR‐564/ZIC2 axis	5
Unveiling Anoikis‐related genes: A breakthrough in the prognosis of bladder cancer	5
Studying the mechanism underlying lipid metabolism in osteosarcoma based on transcriptomic RNA sequencing and single‐cell data	5
STAT2‐induced linc02231 promotes tumorigenesis and angiogenesis through modulation of hnRNPA1/ANGPTL4 in colorectal cancer	5
LINC01291 promotes hepatocellular carcinoma development by targeting the miR‐186‐5p/OXSR1 axis	5
Associations between common genetic variants in microRNAs and Hirschsprung disease susceptibility in Southern Chinese children	5
TaqI polymorphism T/t genotypes at the vitamin D receptor gene (VDR) are associated with increased serum vitamin D levels in mild and moderate psoriasis vulgaris: A pilot study	5
SLC45A4 promotes glycolysis and prevents AMPK/ULK1‐induced autophagy in TP53 mutant pancreatic ductal adenocarcinoma	5
Association between HLA alleles and Epstein–Barr virus Zta‐IgA serological status in healthy males from southern China	5
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells	5
Global brain delivery of neuroligin 2 gene ameliorates seizures in a mouse model of epilepsy	5
The long non‐sacoding RNA TMEM147‐AS1/miR‐133b/ZNF587 axis regulates the Warburg effect and promotes prostatic carcinoma invasion and proliferation	5
Extracellular vesicles from bone marrow mesenchymal stem cells alleviate acute rejection injury after liver transplantation by carrying miR‐22‐3p and inducing M2 polarization of Kupffer cells	5
Profiling T cell receptor β‐chain in responders after immunization with recombinant hepatitis B vaccine	5
LncRNA CDKN2B‐AS1 contributes to glioma development by regulating the miR‐199a‐5p/DDR1 axis	5
Downregulation of indolethylamine N‐methyltransferase is an early event in the rat hepatocarcinogenesis and is associated with poor prognosis in hepatocellular carcinoma patients	5
Long non‐coding RNA KCNQ1OT1 promotes proliferation, migration and invasion via targeting miR‐134 in retinoblastoma	5
Withdrawn: Y.Yin, X.Lu, M.Yang, J.Shangguan, Y.Zhang. Inhibition of lncRNA MALAT1 reduces myocardial ischemia–reperfusion injury of rat cardiomyocytes through regulating the miR‐135a‐5p/HIF1AN axis, p	5
Withdrawn: Z.Cui, Q.Sun, W.Yan, Q.Han, G.Wang, Y.Hu. The role of miR‐320a and its target gene GMEB1 in epithelial‐mesenchymal transition and invasion of colorectal cancer, published in The Journal of	4
The role and mechanism of long non‐coding RNAs in homologous recombination repair of radiation‐induced DNA damage	4
Inhibition of AHNAK nucleoprotein 2 alleviates pulmonary fibrosis by downregulating the TGF‐β1/Smad3 signaling pathway	4
The role of ABCB1 gene polymorphisms in steroid‐resistant nephrotic syndrome: Evidence from a meta‐analysis of steroid‐receiving patients	4
Potentially functional genetic variants of VAV2 and PSMA4 in the immune‐activation pathway and non‐small cell lung cancer survival	4
Variants in TNF and NOS3 (eNOS) genes associated with sepsis in adult patients	4
Haplotype analysis and linkage disequilibrium of ApoB gene polymorphisms and its relationship with hyperlipidemia in patients with acne vulgaris	4
Novel algorithm for diagnosis of Arrhythmogenic cardiomyopathy and dilated cardiomyopathy: Key gene expression profiling using machine learning	4
Methyltransferase‐like 3 modulates osteogenic differentiation of adipose‐derived stem cells in osteoporotic rats	4
Prenatal diagnosis of Walker–Warburg syndrome due to compound mutations in the B3GALNT2 gene	4
Complete remission following icotinib administration in an advanced ectopic thymic carcinoma patient harbouring the EGFR exon 19 deletion	4
Marked increase in tumor transfection with a truncated branched polymer	4
Circular RNA HIPK3 facilitates ferroptosis in gestational diabetes mellitus by regulating glutathione peroxidase 4 DNA methylation	4
Investigating the prognostic role of lncRNAs associated with disulfidptosis‐related genes in clear cell renal cell carcinoma	4
Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population	4
Withdrawn: L.Xuan, Z.Sun, J.Wang, S.Gao. Long non‐coding RNA SNHG8 promotes ovarian cancer progression through serving as a sponge for miR‐1270 to regulate S100A11 expression, published in The Journal	4
Successful AAV8 readministration: Suppression of capsid‐specific neutralizing antibodies by a combination treatment of bortezomib and CD20 mAb in a mouse model of Pompe disease	4
The pathological tissue expression pattern and clinical significance of m6A‐regulatory genes in non‐small cell lung cancer	4
New association between splicing factor‐coding gene polymorphisms and the risk of acute lymphoblastic leukemia in southern Chinese children: A five‐center case–control study	4
An m1A/m6A/m5C‐associated long non‐coding RNA signature: Prognostic and immunotherapeutic insights into cervical cancer	4