Journal of Gene Medicine

Papers
(The median citation count of Journal of Gene Medicine is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population33
Circulating microvesicles miR139‐3p from bronchopulmonary dysplasia aggravates pulmonary vascular simplification by targeting 4E binding protein 133
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Reappraising the role of chronic inflammatory burden in heart failure24
Interaction Between YTH Domain‐Containing Family Protein 2 and SET Domain‐Containing Lysine Methyltransferase 7 Suppresses Autophagy in Osteoarthritis Chondrocytes, Exacerbating Cartilage Damage23
Icariin Facilitates Osteogenic Differentiation and Suppresses Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Enhancing SOST Methylation in Postmenopausal Osteoporosis19
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CRISPR‐Cas9 screening identified lethal genes enriched in necroptosis pathway and of prognosis significance in osteosarcoma18
RNA sequencing and bioinformatics analysis revealed PACSIN3 as a potential novel biomarker for platinum resistance in epithelial ovarian cancer18
The CHST11 gene is linked to lung cancer and pulmonary fibrosis18
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T‐cell exhaustion: A potential target biomarker of the tumour microenvironment affecting oesophageal adenocarcinoma16
Targeted gene next‐generation sequencing reveals genomic profile in a cohort of 46 Chinese patients with breast cancer16
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Transcriptome and single‐cell sequencing analysis in tumor microenvironment15
Reducing the transcriptional read‐through rate of a lentiviral vector for β‐thalassemia gene therapy14
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Metabolic and immune‐related gene signatures: Predictive stratification and prognostic implications in gastric cancer14
USP31 serves as a potential biomarker for predicting prognosis and immune responses for clear cell renal cell carcinoma via single‐cell and bulk RNA‐sequencing14
Cytotoxic T‐lymphocytes in acute myeloid leukemia: Monitoring prognosis and guiding treatment choice13
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Diverse cell death patterns‐related signature for predicting prognosis and drug sensitivity of osteosarcoma patients13
Peroxisome proliferator‐activated receptors signature reveal the head and neck squamous cell carcinoma energy metabolism phenotype and clinical outcome13
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Age‐related genes USP2 and ARG2 are involved in the reduction of immune cell infiltration in elderly patients with rheumatoid arthritis13
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Characterization of the evolution trajectory and immune profiling of new histologic patterns in lung adenocarcinoma13
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Minicircle‐based expression of vascular endothelial growth factor in mesenchymal stromal cells from diverse human tissues12
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Application of CAR‐T cell technology in autoimmune diseases and human immunodeficiency virus infection treatment11
Zebrafish in understanding molecular pathophysiology, disease modeling, and developing effective treatments for Rett syndrome11
A glycosylation signature for predicting the progression and immunotherapeutic response of prostate cancer11
Lnc00113 promotes triple‐negative breast cancer progression via the NOB‐1/MAPK signaling axis11
A novel compound heterozygous variant linked to hematuria in a family with hereditary factor VII deficiency10
Leveraging SEER data through machine learning to predict distant lymph node metastasis and prognosticate outcomes in hepatocellular carcinoma patients10
Function and prognostic value of N6‐methyladenosine‐modified RNAs in lung adenocarcinoma10
Hyperfunction variant rs708035 of interleukin 1 receptor‐associated kinases 2 gene involved in the predisposition of leprosy infection10
Identification of module genes and functional pathway analysis in septic shock subtypes by integrated bioinformatics analysis10
X‐linked BCOR variants identified in Chinese Han patients with congenital heart disease10
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Novel algorithm for diagnosis of Arrhythmogenic cardiomyopathy and dilated cardiomyopathy: Key gene expression profiling using machine learning10
VEGF165 gene‐modified human umbilical cord blood mesenchymal stem cells protect against acute liver failure in rats9
RNA expression profiling in lymphoblastoid cell lines from mutated and non‐mutated amyotrophic lateral sclerosis patients9
The profile of cytokines against bacterial infection in dental pulp9
Hematopoietic stem cell gene therapy for the treatment of SYNGAP1‐related non‐specific intellectual disability9
Autophagy‐related CMTM6 promotes glioblastoma progression by activating Wnt/β‐catenin pathway and acts as an onco‐immunological biomarker9
Characterization of neutrophil extracellular traps related gene pair for predicting prognosis in hepatocellular carcinoma9
The diagnostic significance of circulating lncRNA ADAMTS9‐AS2 tumor biomarker in non‐small cell lung cancer among the Egyptian population8
Long non‐coding DANCR targets miR‐185‐5p to upregulate LIM and SH3 protein 1 promoting prostate cancer via the FAK/PI3K/AKT/GSK3β/snail pathway8
Association of CYP4A22 gene polymorphisms with cerebral stroke risk in the Chinese Han population8
Fiber modifications enable fowl adenovirus 4 vectors to transduce human cells8
M2 macrophage marker CHI3L2 could serve as a potential prognostic and immunological biomarker in glioma by integrated single‐cell and bulk RNA‐Seq analysis8
Withdrawn: Y.Yin, X.Lu, M.Yang, J.Shangguan, Y.Zhang. Inhibition of lncRNA MALAT1 reduces myocardial ischemia–reperfusion injury of rat cardiomyocytes through regulating the miR‐135a‐5p/HIF1AN axis, p8
NLRC4‐mediated pyroptosis was involved in coagulation disorders of acute pancreatitis8
Shikonin potentiates skin wound healing in Sprague–Dawley rats by stimulating fibroblast and endothelial cell proliferation and angiogenesis8
Downregulated expression of plakophilin‐2 gene in patients with colon adenocarcinoma predicts an unfavorable prognosis and immune infiltrate8
Decoding dysregulated genes, molecular pathways and microRNAs involved in cervical cancer8
Withdrawn: X.Chen, Y.Li, M.Zhang, X.Wu, J.Zhu. Silencing LCK inactivates the NF‐κB pathway to attenuate cartilage injury in osteoarthritis: An in vivo and in vitro study, published in Th8
Withdrawn: Z.Cui, Q.Sun, W.Yan, Q.Han, G.Wang, Y.Hu. The role of miR‐320a and its target gene GMEB1 in epithelial‐mesenchymal transition and invasion of colorectal cancer, published in The Journal of 8
Cuproptosis‐related classification and personalized treatment in lower‐grade gliomas to prompt precise oncology8
lncRNA FBXL19‐AS1 is a diagnosis biomarker for paediatric patients with acute myeloid leukemia7
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Investigating the prognostic role of lncRNAs associated with disulfidptosis‐related genes in clear cell renal cell carcinoma7
WES and Transcriptome Analysis Identifies FN1 as a Candidate Gene for Anterior Segment Dysgenesis7
Genetic variation in catechol‐O‐methyltransferase is associated with individual differences in conditioned pain modulation in healthy subjects7
Identification of novel homozygous missense and deletion mutations manifesting oligospermia infertility in Kashmiri population7
The long non‐sacoding RNA TMEM147‐AS1/miR‐133b/ZNF587 axis regulates the Warburg effect and promotes prostatic carcinoma invasion and proliferation7
Long non‐coding RNA KCNQ1OT1 promotes proliferation, migration and invasion via targeting miR‐134 in retinoblastoma7
Transcriptome mapping of renal clear cell carcinoma revealed by machine learning algorithm based on enhanced computed tomography images7
Hsa_circ_0040809 regulates colorectal cancer development by upregulating methyltransferase DNMT1 via targeting miR‐515‐5p6
Prognosis and therapy in thyroid cancer by gene signatures related to natural killer cells6
Long non‐coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR‐326/PKM2 axis6
Amino acids and their roles in tumor immunotherapy of breast cancer6
Global analysis of urinary extracellular vesicle small RNAs in autosomal dominant polycystic kidney disease6
Bioinformatics‐based analysis of programmed cell death pathway and key prognostic genes in gastric cancer: Implications for the development of therapeutics6
Haplotype analysis and linkage disequilibrium of ApoB gene polymorphisms and its relationship with hyperlipidemia in patients with acne vulgaris6
Expression pattern of long non‐coding RNAs MALAT1 and MEG3 in COVID‐19 patients6
AKT/FOXM1/STMN1 signaling pathway activation by SMC1A promotes tumor growth in breast cancer6
Circular RNA circ_0001588 sponges miR‐211‐5p to facilitate the progression of glioblastoma via up‐regulating YY1 expression6
Leveraging human–mouse studies to advance the genetics of hearing impairment in Africa5
RETRACTION: Long non‐coding RNA KCNQ1OT1 Promotes the Progression of Gastric Cancer via the miR‐145‐5p/ARF6 Axis5
Dissecting the molecular profiling and tumor immune microenvironment of three subtypes of esophageal cancer5
Vitamin D receptor gene polymorphismTaqI(rs731236) and its association with the susceptibility to coronary artery disease among Pakistani population5
lncRNA OIP5‐AS1 knockdown or miR‐223 overexpression can alleviate LPS‐induced ALI/ARDS by interfering with miR‐223/NLRP3‐mediated pyroptosis5
Single‐cell sequencing reveals the correlation of aggrephagy signaling and multiple myeloma immune microenvironment composition5
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Global brain delivery of neuroligin 2 gene ameliorates seizures in a mouse model of epilepsy5
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Potentially functional genetic variants of the notch signaling pathway genes predict survival of Chinese patients with esophageal squamous cell carcinoma5
USP18 promotes colon adenocarcinoma progression via targeting the ERK‐MNK signaling pathway5
Identification and characterization of RAC1‐related immune and prognostic subtypes of hepatocellular carcinoma5
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Icariside II in NSCLC and COVID‐19: Network pharmacology and molecular docking study5
Hsa_circRNA_102229 facilitates the progression of triple‐negative breast cancer via regulating the miR‐152‐3p/PFTK1 pathway5
Safety of intravitreally delivered AAV2 vector‐mediated multi‐characteristic opsin genetic construct in wild type beagle dogs5
Adenovirus VA RNAs impair maturation of primary microRNA5
Exploring the mechanism underlying the therapeutic effects of butein in colorectal cancer using network pharmacology and single‐cell RNA sequencing data4
Dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in breast cancer: A comprehensive analysis4
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Interleukin‐17A educated hepatic stellate cells promote hepatocellular carcinoma occurrence through fibroblast activation protein expression4
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Association study of miR‐149, miR‐196a2, and miR‐499a polymorphisms with coronary artery aneurysm of Kawasaki disease in southern Chinese population4
Causal effects of female reproductive features on nonalcoholic fatty liver disease: A mendelian randomization study4
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sRNA21, a novel small RNA, protects Mycobacterium abscessus against oxidative stress4
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Comprehensive analysis of histone acetylation‐related genes in glioblastoma and lower‐grade gliomas: Insights into drug sensitivity, molecular subtypes, immune infiltration, and prognosis4
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A novel variant of C12orf4 linked to autosomal recessive intellectual disability type 66 with phenotype expansion4
LINC01291 promotes hepatocellular carcinoma development by targeting the miR‐186‐5p/OXSR1 axis4
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Natural killer cell‐based signature: Prognostic analysis in head and neck squamous cell carcinoma4
A novel PPRC1 point mutation in a Chinese family with premature ovarian failure: A case study4
Downregulation of indolethylamine N‐methyltransferase is an early event in the rat hepatocarcinogenesis and is associated with poor prognosis in hepatocellular carcinoma patients3
An m1A/m6A/m5C‐associated long non‐coding RNA signature: Prognostic and immunotherapeutic insights into cervical cancer3
mmu‐miR‐185 regulates osteoclasts differentiation and migration by targeting Btk3
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Identification and functional analysis of genetic variants of ISL1 gene promoter in human atrial septal defects3
COL3A1‐positive endothelial cells influence LUAD prognosis and regulate LUAD carcinogenesis by NCL–PI3K–AKT axis3
Disulfidptosis‐related PABPC3 promotes tumor progression and inhibits immune activity in osteosarcoma3
HGF facilitates methylation of MEG3, potentially implicated in vemurafenib resistance in melanoma3
B4GALNT1 promotes carcinogenesis by regulating epithelial–mesenchymal transition in hepatocellular carcinoma based on pan‐cancer analysis3
Construction and validation of molecular subtype and signature of immune cell‐related telomeric genes and prediction of prognosis and immunotherapy efficacy in ovarian cancer patients3
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MEG3 shuttled by exosomes released from human bone marrow mesenchymal stem cells promotes TP53 stability to regulate MCM5 transcription in keloid fibroblasts3
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Long non‐coding RNA LGALS8‐AS1 facilitates PLAGL2‐mediated malignant phenotypes in gastric cancer3
miR‐451a suppresses the proliferation and migration of high‐grade serous ovarian cancer by targeting RAB5A through the Ras/Raf/MEK/ERK pathway3
Ovarian cancer classification and prognosis assessment model based on prognostic target genes in key microRNA‐target gene networks3
Integrative analysis of an endoplasmic reticulum stress‐related signature in multiple myeloma3
Prognostic analysis and validation of lncRNAs in bladder cancer on the basis of neutrophil extracellular traps3
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Characterization of the m6A/m1A/m5C/m7G‐related regulators on the prognosis and immune microenvironment of glioma by integrated analysis of scRNA‐seq and bulk RNA‐seq data3
Antisense lncRNA‐RP11‐498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species‐induced mitophagy3
PCSK9 genetic (rs11591147) and epigenetic (DNA methylation) modifications associated with PCSK9 expression and serum proteins in CAD patients3
Relevance of pyroptosis‐associated genes in nasopharyngeal carcinoma diagnosis and subtype classification3
Multiomics blueprint of PANoptosis in deciphering immune characteristics and prognosis stratification of glioma patients3
Ovarian carcinoma immune‐related microRNA affects the heterogeneity of the endocrine microenvironment and anti‐tumor immune pattern3
A novel homozygous synonymous splicing variant in SELENOI gene causes spastic paraplegia 812
Constructing and validating a risk model based on neutrophil‐related genes for evaluating prognosis and guiding immunotherapy in colon cancer2
Combination therapy with chitosan/siRNA nanoplexes targeting PDGF‐D and PDGFR‐β reveals anticancer effect in breast cancer2
Inhibition of circ_0081234 reduces prostate cancer tumor growth and metastasis via the miR‐1/MAP 3 K1 axis2
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Histone acetylation gene‐based biomarkers as novel markers of the immune microenvironment in glioblastoma2
Genome wide analysis of dexamethasone stimulated mineralization in human dental pulp cells by RNA sequencing2
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BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells2
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Multi‐omics analysis reveals that ferroptosis‐related gene CISD2 is a prognostic biomarker of head and neck squamous cell carcinoma2
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Down‐regulation of circITCH promotes osteosarcoma development and resistance to doxorubicin via the miR‐524/RASSF6 axis2
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Linoleic‐acid‐substituted polyethylenimine to silence heat shock protein 90B1 (HSP90B1) to inhibit migration of breast cancer cells2
Anisomycin inhibits the activity of human ovarian cancer stem cells via regulating antisense RNA NCBP2‐AS2/MEK/ERK/STAT3 signaling2
Erxian Decoction‐induced serum exosomes slowed bone marrow mesenchymal stem cell senescence through mitophagy2
Network pharmacology and bioinformatics analysis on the underlying mechanisms of baicalein against oral squamous cell carcinoma2
Stable transduction of the neonatal mouse liver using a hybrid rAAV/sleeping beauty transposon gene delivery system2
A LncRNA gene polymorphism (rs1814343) is associated with the risk of coronary artery lesions in southern Chinese Kawasaki disease patients2
Exploration of the prognostic prediction value of the PANoptosis‐based risk score and its correlation with tumor immunity in lung adenocarcinoma2
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Circular RNA HIPK3 facilitates ferroptosis in gestational diabetes mellitus by regulating glutathione peroxidase 4 DNA methylation2
Homologous recombination repair gene‐based risk model predicts prognosis and immune microenvironment for primary lung cancer after previous malignancies2
Synovial mesenchymal stem cell‐derived extracellular vesicles containing microRN555A‐26a‐5p ameliorate cartilage damage of osteoarthritis2
Extracellular vesicle‐packaged miR‐181c‐5p from epithelial ovarian cancer cells promotes M2 polarization of tumor‐associated macrophages via the KAT2B/HOXA10 axis2
Withdrawn: X.Sun, J.Sun, D.Zhao, Y.Song, L.Yu. Phosphatase and actin regulator 1 rs9349379 polymorphism is associated with an elevated susceptibility to coronary artery disease: a meta‐analysis, publi2
Association of matrix metalloproteinase‐2 gene variants with diabetic nephropathy risk2
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Key biomarkers in cerebral arteriovenous malformations: Updated review2
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STAT2‐induced linc02231 promotes tumorigenesis and angiogenesis through modulation of hnRNPA1/ANGPTL4 in colorectal cancer2
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Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR‐2172
New function of a well‐known promoter: Enhancer activity of minimal CMV promoter enables efficient dual‐cassette transgene expression2
Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple‐vessel disease patients2
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Development of oncolytic and gene therapy vectors based on adenovirus serotype 4 as an alternative to adenovirus serotype 52
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Histidine‐enhanced gene delivery systems: The state of the art2
LncRNA CDKN2B‐AS1 contributes to glioma development by regulating the miR‐199a‐5p/DDR1 axis2
Identification of a novel LRRC4C‐ALK fusion in lung adenocarcinoma and outcome of the response to anaplastic lymphoma kinase inhibitors2
CSRP3, p.Arg122*, is responsible for hypertrophic cardiomyopathy in a Chinese family2
Inhibition of hsa_circ_0003489 shifts balance from autophagy to apoptosis and sensitizes multiple myeloma cells to bortezomib via miR‐874‐3p/HDAC1 axis2
Idiopathic Pulmonary Fibrosis Is Associated With Type 1 Diabetes: A Two‐Sample Mendelian Randomization Study2
Gene therapy clinical trials worldwide to 2023—an update2
Bone marrow overexpression of SNAI1 is an early indicator of intrinsic drug resistance in patients with de novo acute myeloid leukemia2
Circ_0006006 facilitates non‐small cell lung cancer progression by modulating miR‐924/SRSF7 axis2
Inhibition of HIST1H2AB suppresses the proliferation of lung adenocarcinoma2
Antigen processing and presentation‐related signature‐derived BNIP3 is a novel oncogene and immunotherapy determinant in osteosarcoma based on machine learning and in vitro validation2
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Design of a new cell penetrating peptide for DNA, siRNA and mRNA delivery2
Circular RNA ITCH attenuates the progression of nasopharyngeal carcinoma by inducing PTEN upregulation via miR‐2142
Circulating miR‐181a and miR‐223 expression with the potential value of biomarkers for the diagnosis of systemic lupus erythematosus and predicting lupus nephritis2
lncRNA ANRIL accelerates wound healing in diabetic foot ulcers via modulating HIF1A/VEGFA signaling through interacting with FUS2
Autophagy‐related risk signature based on CDNK2A to facilitate survival prediction of patients with endometrial cancer2
The lncRNA HOXA11‐AS acts as a tumor promoter in breast cancer through regulation of the miR‐125a‐5p/TMPRSS4 axis1
Exploration of the prognostic effect of costimulatory genes in bladder cancer1
Tumor microenvironment phenotypes and prognostic evaluation tools for osteosarcoma characterized by different prognostic outcomes and immunotherapy responses1
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Metabolism‐related gene vaccines and immune infiltration in ovarian cancer: A novel risk score model of machine learning1
A novel anoikis‐related prognostic signature associated with prognosis and immune infiltration landscape in lung adenocarcinoma1
Identification of secretory pathway‐related genes based on Random Forest algorithm to predict the prognosis and immunotherapy response of hepatocellular carcinoma1
Potentially functional genetic variants of VAV2 and PSMA4 in the immune‐activation pathway and non‐small cell lung cancer survival1
Profiling T cell receptor β‐chain in responders after immunization with recombinant hepatitis B vaccine1
Novel molecular insights into pyroptosis in triple‐negative breast cancer prognosis and immunotherapy1
Exploring the interplay between bisphenol A exposure, the immune microenvironment and hepatocellular carcinoma progression1
Expression and prognostic value of cell‐cycle‐associated genes in lung squamous cell carcinoma1
Disrupting methyl‐CpG‐binding protein 2 expression induces the transformation of induced pluripotent stem cell cardiomyocytes into pacemaker‐like cells by insulin gene enhancer binding protein 11
Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia1
Apoptosis pathways and osteoporosis: An approach to genomic analysis1
Maternal ApoE genotype and risk of recurrent pregnancy loss: An updated systematic review and meta‐analysis1
MiR‐431 promotes cardiomyocyte proliferation by targeting FBXO32 expression1
A non‐canonical role of endothelin converting enzyme 1 (ECE1) in promoting lung cancer development via directly targeting protein kinase B (AKT)1
Activation of toll‐like receptor 4/nuclear factor‐kappa B signaling by triggering a receptor expressed on myeloid cells 1 promotes alveolar macrophage M1 polarization and exacerbates septic acute lung1
Homologous recombination deficiency reflects the heterogeneity and monitoring treatment response for patients with breast cancer1
Exploration of s new biomarker in osteosarcoma and association with clinical outcomes: TOP2A+cancer associated fibroblasts1
A mass spectrometry assay for detection of endogenous and lentiviral engineered hemoglobin in cultured cells and sickle cell disease mice1
lncRNA MALAT1 promotes osteogenic differentiation through the miR‐217/AKT3 axis: A possible strategy to alleviate osteoporosis1
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Evaluation of CRISPR/Cas9 exon‐skipping vector for choroideremia using human induced pluripotent stem cell‐derived RPE1
Marked increase in tumor transfection with a truncated branched polymer1
Long non‐coding RNA linc00659 promotes tumour progression by regulating FZD6/Wnt/β‐catenin signalling pathway in colorectal cancer via m6A reader IGF2BP11
Integrative in silico approaches to analyse microRNA‐mediated responses in human diseases1
The activity of cytokines in dental pulp1
Hsa_circ_0003596 enhances the development of cell renal clear cell carcinoma through the miR‐502‐5p/IGF1/PI3K/AKT axis1
Augmentation of Solid Tumor Immunotherapy With IL‐121
Development of a novel prognostic signature based on single‐cell combined bulk RNA analysis in breast cancer1
A novel model incorporating chromatin regulatory factors for risk stratification, prognosis prediction, and characterization of the microenvironment in Wilms tumor1
Actin filament‐associated protein 1‐antisense RNA1 promotes the development and invasion of tongue squamous cell carcinoma via the AFAP1‐AS1/miR‐133a‐5p/ZIC2 axis1
Unveiling the immunogenomic landscape of cholangiocarcinoma: Identifying new prognostic markers and therapeutic targets based on CCL5 expression1
Association between HLA alleles and Epstein–Barr virus Zta‐IgA serological status in healthy males from southern China1
Three molecular subtypes and a five‐gene signature for hepatocellular carcinoma based on m7G‐related classification1
Studying the mechanism underlying lipid metabolism in osteosarcoma based on transcriptomic RNA sequencing and single‐cell data1
The inflammatory response‐related robust machine learning signature in endometrial cancer: Based on multi‐cohort studies1
Dysregulated cholesterol regulatory genes as a diagnostic biomarker for cancer1
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YAP1 Overexpression Enhances the Aerobic Glycolysis Process via Suppression of EGLN2 in Pancreatic Ductal Adenocarcinoma1
Successful liver transduction by re‐administration of different adeno‐associated virus vector serotypes in mice1
mRNA expression insights: Unraveling the relationship between COPD and lung cancer1
Impact of inflammatory cytokine and adipokine gene variations in the development of HIV‐associated lipodystrophy1
circANKRD28 inhibits cisplatin resistance in non‐small‐cell lung cancer through the miR‐221‐3p/SOCS3 axis1
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Integrated mRNA and microRNA profiling in lung tissue and blood from human silicosis1
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