Journal of Gene Medicine

Article	Citations
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Application of CAR‐T cell technology in autoimmune diseases and human immunodeficiency virus infection treatment	51
Hyperfunction variant rs708035 of interleukin 1 receptor‐associated kinases 2 gene involved in the predisposition of leprosy infection	42
Withdrawn: Z.Cui, Q.Sun, W.Yan, Q.Han, G.Wang, Y.Hu. The role of miR‐320a and its target gene GMEB1 in epithelial‐mesenchymal transition and invasion of colorectal cancer, published in The Journal of	29
Identification of module genes and functional pathway analysis in septic shock subtypes by integrated bioinformatics analysis	29
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Downregulated expression of plakophilin‐2 gene in patients with colon adenocarcinoma predicts an unfavorable prognosis and immune infiltrate	24
Withdrawn: X.Chen, Y.Li, M.Zhang, X.Wu, J.Zhu. Silencing LCK inactivates the NF‐κB pathway to attenuate cartilage injury in osteoarthritis: An in vivo and in vitro study, published in Th	24
Diverse cell death patterns‐related signature for predicting prognosis and drug sensitivity of osteosarcoma patients	24
WES and Transcriptome Analysis Identifies FN1 as a Candidate Gene for Anterior Segment Dysgenesis	22
Lnc00113 promotes triple‐negative breast cancer progression via the NOB‐1/MAPK signaling axis	22
Haplotype analysis and linkage disequilibrium of ApoB gene polymorphisms and its relationship with hyperlipidemia in patients with acne vulgaris	22
Interaction Between YTH Domain‐Containing Family Protein 2 and SET Domain‐Containing Lysine Methyltransferase 7 Suppresses Autophagy in Osteoarthritis Chondrocytes, Exacerbating Cartilage Damage	21
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Long non‐coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR‐326/PKM2 axis	19
YTHDF3 Promotes N6‐Methyladenosine Modification of SOCS1 to Inhibit JAK1/STAT3 Pathway in the Pathogenesis of Preeclampsia	19
Adenovirus VA RNAs impair maturation of primary microRNA	18
Constructing and validating a risk model based on neutrophil‐related genes for evaluating prognosis and guiding immunotherapy in colon cancer	18
Synovial Mesenchymal Stem Cell–Derived Exosomal miR‐3614‐5p Regulates Macrophage Polarization by Targeting ANXA2 to Relieve Knee Osteoarthritis	17
Autophagy‐related risk signature based on CDNK2A to facilitate survival prediction of patients with endometrial cancer	17
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Downregulation of indolethylamine N‐methyltransferase is an early event in the rat hepatocarcinogenesis and is associated with poor prognosis in hepatocellular carcinoma patients	16
Long Noncoding RNAs (LncRNA‐4.2, LncRNA‐4.3) and Their Correlation With Hypoxia‐Related Biomarkers in Breast Cancer	15
Antigen processing and presentation‐related signature‐derived BNIP3 is a novel oncogene and immunotherapy determinant in osteosarcoma based on machine learning and in vitro validation	15
Integrative analysis of an endoplasmic reticulum stress‐related signature in multiple myeloma	14

Bone marrow overexpression of SNAI1 is an early indicator of intrinsic drug resistance in patients with de novo acute myeloid leukemia	14
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Integrated mRNA and microRNA profiling in lung tissue and blood from human silicosis	14
Interleukin‐17A educated hepatic stellate cells promote hepatocellular carcinoma occurrence through fibroblast activation protein expression	14
Expression and prognostic value of cell‐cycle‐associated genes in lung squamous cell carcinoma	14
Pharmacogenomic evaluation of CYP2C19 alleles linking low clopidogrel response and the risk of acute coronary syndrome in Indians	13
Anisomycin inhibits the activity of human ovarian cancer stem cells via regulating antisense RNA NCBP2‐AS2/MEK/ERK/STAT3 signaling	13
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Studying the mechanism underlying lipid metabolism in osteosarcoma based on transcriptomic RNA sequencing and single‐cell data	13
A novel anoikis‐related prognostic signature associated with prognosis and immune infiltration landscape in lung adenocarcinoma	13
lncRNA MALAT1 promotes osteogenic differentiation through the miR‐217/AKT3 axis: A possible strategy to alleviate osteoporosis	12
Construction and validation of risk model of EMT‐related prognostic genes for kidney renal clear cell carcinoma	12
Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia	12
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FOXA3: A Novel Tumor Suppressor in Esophageal Squamous Cell Carcinoma	12
Activation of toll‐like receptor 4/nuclear factor‐kappa B signaling by triggering a receptor expressed on myeloid cells 1 promotes alveolar macrophage M1 polarization and exacerbates septic acute lung	12
circANKRD28 inhibits cisplatin resistance in non‐small‐cell lung cancer through the miR‐221‐3p/SOCS3 axis	12
Successful liver transduction by re‐administration of different adeno‐associated virus vector serotypes in mice	12
Exploration of YBX1 role in the prognostic value and immune characteristics by single‐cell and bulk sequencing analysis for liver hepatocellular carcinoma	11
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Sequence variants in the BTD underlying biotinidase deficiency in families of Pakistani origin	10
Insights into the heterogeneity of the tumor microenvironment in lung adenocarcinoma and squamous carcinoma through single‐cell transcriptomic analysis: Implications for distinct immunotherapy outcome	10
Homozygous missense variant in POPDC3 causes recessive limb‐girdle muscular dystrophy type 26	10
Genomic instability‐associated two‐miRNA signature as a novel prognostic biomarker in breast cancer	10
Comprehensive profiling of endocrine metabolism identifies a novel signature with robust predictive value in ovarian cancer	10
Genetically predicted blood metabolites mediate the association between circulating immune cells and pancreatic cancer: A Mendelian randomization study	10
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Non‐coding RNAs are correlated to TGF‐β receptor type 2 in patients with colorectal cancer	10
A variant in sperm‐specific glycolytic enzyme enolase 4 (ENO4) causes human male infertility	9
Identification of SGMS2 as a molecule involved in natural killer cell recruitment and its in‐deep analysis in the liver cancer microenvironment: Evidence from large populations cohort	9
Development of an ubiquitin‐proteasome system signature for predicting prognosis and providing therapeutic guidance for patients with triple‐negative breast cancer	9
A combined diagnostic model based on circulating tumor cell in patients with solitary pulmonary nodules	9
FPPS Downregulation Attenuates Endoplasmic Reticulum Stress in Pulmonary Epithelial Cells	9
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Cis‐regulation of antisense non‐coding RNA at the JAZF1 locus in type 2 diabetes	9
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Circulating plasma miR222‐3P status and its potential diagnostic performance in prostate cancer	8
Prenatal diagnosis of Walker–Warburg syndrome due to compound mutations in the B3GALNT2 gene	8
Silencing of circDPP4 suppresses cell progression of human prostate cancer and enhances docetaxel cytotoxicity through regulating the miR‐564/ZIC2 axis	8
Insights Into the Dysfunctional Communication Switches Targeting Osteocyte Mechanotransduction and Lacunar–Canalicular Gene Network in Pathogenesis of Osteoarthritis	8
KDM1A Facilitates Oncogenic Potential in Colorectal Cancer Progression Through the Activation of AXIN/GSK3β/β‐Catenin Signaling Pathways: Evidence From Integrated Transcriptomics and In Vitro Studies	8
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JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial–mesenchymal transition in lung adenocarcinoma	8
Implantation of human urine stem cells promotes neural repair in spinal cord injury rats associated cadeharin‐1 and integrin subunit beta 1 expression	7
A comprehensive study of oxidative stress‐related effects on the prognosis and drug therapy of cervical cancer	7
Biocompatible hydroxyapatite‐based nano vehicle bypasses viral transduction and enables sustained silencing of a pluripotency marker gene, demonstrating desired differentiation in mouse embryonic stem	7
Development of the prognostic value in lung adenocarcinoma based on anoikis‐related genes and initial experimental validation	7

Silencing N29 Regulated miR‐193b‐5p/TGFBR2 Axis to Mitigate the Progression of Cardiac Hypertrophy	7
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Mechanism of Tourette Syndrome Induced by ABGA‐Mediated CaMKII‐TH Pathway	7
FN1 and cancer‐associated fibroblasts markers influence immune microenvironment in clear cell renal cell carcinoma	7
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Identification of prognostic value of anoikis‐related gene score model combined with tumor microenvironment score models in esophageal squamous cell carcinoma	7
Machine learning reveals PANoptosis as a potential reporter and prognostic revealer of tumour microenvironment in lung adenocarcinoma	7
A‐to‐I RNA Edited miR‐605‐3p Has a Heightened Anti‐Tumor Effect in Colorectal Cancer Through Modulating Immune Infiltration Mediated by CDK6	6
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Idiopathic Pulmonary Fibrosis Is Associated With Type 1 Diabetes: A Two‐Sample Mendelian Randomization Study	6
Exploring the Protein–Metabolite Interplay to Discover Novel Drug Targets for Alzheimer's Disease	6
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Novel algorithm for diagnosis of Arrhythmogenic cardiomyopathy and dilated cardiomyopathy: Key gene expression profiling using machine learning	6
Reappraising the role of chronic inflammatory burden in heart failure	6
The profile of cytokines against bacterial infection in dental pulp	6
Anti‐Glutamic Acid Decarboxylase 65 (GAD65) Antibodies and Neurological Syndromes	6
Bioinformatics‐based analysis of programmed cell death pathway and key prognostic genes in gastric cancer: Implications for the development of therapeutics	6
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Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR‐217	6
Reducing the transcriptional read‐through rate of a lentiviral vector for β‐thalassemia gene therapy	6
Characterization of the evolution trajectory and immune profiling of new histologic patterns in lung adenocarcinoma	6
lncRNA OIP5‐AS1 knockdown or miR‐223 overexpression can alleviate LPS‐induced ALI/ARDS by interfering with miR‐223/NLRP3‐mediated pyroptosis	6
Hsa_circ_0003596 enhances the development of cell renal clear cell carcinoma through the miR‐502‐5p/IGF1/PI3K/AKT axis	5
Apoptosis pathways and osteoporosis: An approach to genomic analysis	5
Long non‐coding RNA linc00659 promotes tumour progression by regulating FZD6/Wnt/β‐catenin signalling pathway in colorectal cancer via m6A reader IGF2BP1	5
Three molecular subtypes and a five‐gene signature for hepatocellular carcinoma based on m7G‐related classification	5
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A novel variant of C12orf4 linked to autosomal recessive intellectual disability type 66 with phenotype expansion	5
Histidine‐enhanced gene delivery systems: The state of the art	5
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Novel molecular insights into pyroptosis in triple‐negative breast cancer prognosis and immunotherapy	5
Network pharmacology and bioinformatics analysis on the underlying mechanisms of baicalein against oral squamous cell carcinoma	5
Inhibition of HIST1H2AB suppresses the proliferation of lung adenocarcinoma	5
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USP18 promotes colon adenocarcinoma progression via targeting the ERK‐MNK signaling pathway	5
sRNA21, a novel small RNA, protects Mycobacterium abscessus against oxidative stress	5
Metabolism‐related gene vaccines and immune infiltration in ovarian cancer: A novel risk score model of machine learning	5
Integrated transcriptome, proteome and single‐cell sequencing uncover the prognostic and immunological features of colony‐stimulating factor 3 receptor in pan‐cancer	5
Exploring Potential Hub Genes and Molecular Mechanisms Linking Cardia Carcinoma With Sjögren's Syndrome Based on Comprehensive Bioinformatics Analysis and Machine Learning	5
The inflammatory response‐related robust machine learning signature in endometrial cancer: Based on multi‐cohort studies	5
A Treg‐related riskscore model may improve the prognosis evaluation of colorectal cancer	5
Leveraging human–mouse studies to advance the genetics of hearing impairment in Africa	5
Identification and characterization of RAC1‐related immune and prognostic subtypes of hepatocellular carcinoma	5
Homologous recombination repair gene‐based risk model predicts prognosis and immune microenvironment for primary lung cancer after previous malignancies	5
OMICRON: Virology, immunopathogenesis, and laboratory diagnosis	4
ANKRD37 inhibits trophoblast migration and invasion by regulating the NF‐κB pathway in preeclampsia	4
Issue Information	4
Withdrawn: L.Xuan, Z.Sun, J.Wang, S.Gao. Long non‐coding RNA SNHG8 promotes ovarian cancer progression through serving as a sponge for miR‐1270 to regulate S100A11 expression, published in The Journal	4
Claudin‐1, a Biomarker of Epithelial‐Mesenchymal Transformation, Enhances Lipid Metabolism in Colorectal Cancer Cells to Promote Tumor Metastasis	4
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Baicalin induces ferroptosis in oral squamous cell carcinoma by suppressing the activity of FTH1	4
MYC‐activated LINC00607 promotes hepatocellular carcinoma progression by regulating the miR‐584‐3p/ROCK1 axis	4
Identification and exploration of aging‐related subtypes and distinctive role of SERPINE1 in heart failure based on single‐cell and bulk RNA sequencing data	4
Extracellular vesicles from bone marrow mesenchymal stem cells alleviate acute rejection injury after liver transplantation by carrying miR‐22‐3p and inducing M2 polarization of Kupffer cells	4
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Comprehensive transcriptomic analysis and machine learning reveal unique gene expression profiles in patients with immune‐mediated necrotizing myopathy	4
Multi‐Omics Integrated Analysis of the Protective Effect of Tertiary Lymphoid Structures and Associated Key Regulatory Genes in Human Gallbladder Cancer	4
Inhibition of AHNAK nucleoprotein 2 alleviates pulmonary fibrosis by downregulating the TGF‐β1/Smad3 signaling pathway	4
Characterization of Immune Landscape Based on Homologous Recombination Deficiency Associated Signatures and Identification of Knockdown of ERCC6L to Promote Radiosensitivity in Breast Cancer	4
Early distribution of18 F‐labeled AAV9 vectors in the cerebrospinal fluid after intracerebroventricular or intracisternal magna infusion in non‐human primates	4
Anoikis‐related signature in liver hepatocellular carcinoma defines the YBX1/SPP1 axis by machine learning strategies and valid experiments	4
Retraction: Bladder cancer‐associated transcript 2 contributes to nephroblastoma progression	4
Association between polymorphisms of ABCB1 and prognosis in esophageal squamous cell carcinoma patients treated with taxane	4
miR‐4286 promotes prostate cancer progression by targeting the expression of SALL1	4
Enhancement of adeno‐associated virus serotype 6 transduction into T cells with cell‐penetrating peptides	4
DSCC1 as a Novel Biomarker in Hepatocellular Carcinoma: Diagnostic Potential, Prognostic Impact, Correlation With Key Pathways, and Association With the Immune Landscape	4
Impact of ABCB1, ABCC1, ABCC2, and ABCG2 variants in predicting prognosis and clinical outcomes of north Indian lung cancer patients undergoing platinum‐based doublet chemo	4
Necrotizing apoptosis‐related genes prognosis and treatment effect analysis of osteosarcoma in children	4
Methyltransferase‐like 3 modulates osteogenic differentiation of adipose‐derived stem cells in osteoporotic rats	4
In Silico Analysis of Novel circRNA‐miRNA‐mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation	4

A signature based on neutrophil extracellular trap‐related genes for the assessment of prognosis, immunoinfiltration, mutation and therapeutic response in hepatocellular carcinoma	4
Genetic Relationship Between Menarche and Height in East Asians: Functional Role of LIN28B in Pubertal Timing and Growth	4
Intramyocardial adenoviral vascular endothelial growth factor‐D∆N∆C gene therapy does not induce ventricular arrhythmias	4
M2 macrophage marker CHI3L2 could serve as a potential prognostic and immunological biomarker in glioma by integrated single‐cell and bulk RNA‐Seq analysis	3
Peroxisome proliferator‐activated receptors signature reveal the head and neck squamous cell carcinoma energy metabolism phenotype and clinical outcome	3
Single‐cell analysis of Crohn's disease: Unveiling heterogeneity and evaluating ustekinumab outcomes	3
THBS1 Contributes to Chemoresistance in Ovarian Clear Cell Carcinoma via Promoting Epithelial–Mesenchymal Transition	3
GRIK1‐AS1 deficiency accelerates endometriosis progression by boosting DNMT1‐dependent SFRP1 promoter methylation in endometrial stromal cells	3
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO‐1 Pathways	3
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MEG3 shuttled by exosomes released from human bone marrow mesenchymal stem cells promotes TP53 stability to regulate MCM5 transcription in keloid fibroblasts	3
Potentially functional genetic variants of the notch signaling pathway genes predict survival of Chinese patients with esophageal squamous cell carcinoma	3
Circular RNA HIPK3 facilitates ferroptosis in gestational diabetes mellitus by regulating glutathione peroxidase 4 DNA methylation	3
Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple‐vessel disease patients	3
De Novo Missense Variant in TP63 Gene: Insights on Clinical and Molecular Investigations	3
AKT/FOXM1/STMN1 signaling pathway activation by SMC1A promotes tumor growth in breast cancer	3
Function and prognostic value of N6‐methyladenosine‐modified RNAs in lung adenocarcinoma	3
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Leveraging SEER data through machine learning to predict distant lymph node metastasis and prognosticate outcomes in hepatocellular carcinoma patients	3
Exploring the interplay between bisphenol A exposure, the immune microenvironment and hepatocellular carcinoma progression	3
Viral and non‐viral gene therapy using 3D (bio)printing	3
Maternal ApoE genotype and risk of recurrent pregnancy loss: An updated systematic review and meta‐analysis	3
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Icariside II in NSCLC and COVID‐19: Network pharmacology and molecular docking study	3
Tele‐Genetic Versus Onsite Counseling for APOE Disclosure: A 6‐Month Study of Empowerment, Psychological Distress, and Behavioral Outcomes in Cognitively Diverse Individuals	3
Age‐related genes USP2 and ARG2 are involved in the reduction of immune cell infiltration in elderly patients with rheumatoid arthritis	3
Prognostic analysis and validation of lncRNAs in bladder cancer on the basis of neutrophil extracellular traps	3
Zebrafish in understanding molecular pathophysiology, disease modeling, and developing effective treatments for Rett syndrome	3
Liver Enzyme Genetics and Health Conditions in East Asians: Genetic Architecture and Causal Insights	3
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Metabolic and immune‐related gene signatures: Predictive stratification and prognostic implications in gastric cancer	3
Integrative Analysis Identifies NSUN2 as an Essential Coordinator for Glioma Malignancy and Glucose Metabolism	3
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Development of a novel prognostic signature based on single‐cell combined bulk RNA analysis in breast cancer	3
Impact of inflammatory cytokine and adipokine gene variations in the development of HIV‐associated lipodystrophy	3
Dipeptidyl peptidase 4: A predictor of ferroptosis in ulcerative colitis	3
Single‐cell sequencing reveals the correlation of aggrephagy signaling and multiple myeloma immune microenvironment composition	3
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Sp2 Transcription Factor Alleviates Chondrocyte Loss in Osteoarthritis by Repressing the DVL1‐Dependent Wnt/β‐Catenin Signaling Pathway	3
Genome wide analysis of dexamethasone stimulated mineralization in human dental pulp cells by RNA sequencing	3
Long non‐coding RNA LGALS8‐AS1 facilitates PLAGL2‐mediated malignant phenotypes in gastric cancer	3
RNA sequencing and bioinformatics analysis revealed PACSIN3 as a potential novel biomarker for platinum resistance in epithelial ovarian cancer	3
Cytotoxic T‐lymphocytes in acute myeloid leukemia: Monitoring prognosis and guiding treatment choice	3
Integrative analysis of cuproptosis‐associated genes for predicting immunotherapy response in single‐cell and multi‐cohort studies	2
TaqI polymorphism T/t genotypes at the vitamin D receptor gene (VDR) are associated with increased serum vitamin D levels in mild and moderate psoriasis vulgaris: A pilot study	2
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Autophagy‐related CMTM6 promotes glioblastoma progression by activating Wnt/β‐catenin pathway and acts as an onco‐immunological biomarker	2
The Role of the CLIC/GEEC Endocytic Pathway for Mechanophysical Transfection of DNA	2
The role of ABCB1 gene polymorphisms in steroid‐resistant nephrotic syndrome: Evidence from a meta‐analysis of steroid‐receiving patients	2
Identification of the shared gene signatures and molecular pathways in systemic lupus erythematosus and diffuse large B‐cell lymphoma	2
Adoptive Transfer of T Cells as a Potential Therapeutic Approach in the Bleomycin‐Injured Mouse Lung	2
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Unveiling Anoikis‐related genes: A breakthrough in the prognosis of bladder cancer	2
Pericarpium Trichosanthis Inhibits TGF‐β1‐Smad3 Pathway‐Induced Cardiac Fibrosis in Heart Failure Rats via Upregulation of microRNA‐29b	2
Long noncoding RNA 02027 inhibits proliferation, migration and invasion of hepatocellular carcinoma via miR‐625‐3p/PDLIM5 pathway	2
Strategic deactivation of mRNA COVID‐19 vaccines: New applications for siRNA therapy and RIBOTACs	2
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Combination therapy with chitosan/siRNA nanoplexes targeting PDGF‐D and PDGFR‐β reveals anticancer effect in breast cancer	2
From cancer big data to treatment: Artificial intelligence in cancer research	2
RNA expression profiling in lymphoblastoid cell lines from mutated and non‐mutated amyotrophic lateral sclerosis patients	2
X‐linked BCOR variants identified in Chinese Han patients with congenital heart disease	2
Comparison of immune‐related gene signatures and immune infiltration features in early‐ and late‐onset preeclampsia	2
Artificial Intelligence for Predictive Modeling in CRISPR/Cas9 Gene Editing: a Survey of Methods and Design Strategies	2
SYNGR2 serves as a prognostic biomarker and correlates with immune infiltrates in esophageal squamous cell carcinoma	2
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Circ_0073228 serves as a competitive endogenous ribonucleic acid to facilitate proliferation and inhibit apoptosis of hepatocellular carcinoma cells by the miR‐139‐5p/deoxyribonuclease II axis	2
Clinical and prognostic significance analysis of glycolysis‐related genes in HNSCC	2
The suppression of OTUD7B by miR‐491‐5p enhances the ubiquitination of VEGFA to suppress vascular mimicry in non‐small cell lung cancer	2
Exploration of s new biomarker in osteosarcoma and association with clinical outcomes: TOP2A+cancer associated fibroblasts	2
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Hypoxia‐Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin‐Induced Ferroptosis in Cervical Cancer Cells	2
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miRNAs in Erdheim‐Chester Disease: A Paradigm of Multisystem Histiocytosis	2
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Genome‐wide polygenic risk score for rheumatoid arthritis prediction in postmenopausal women	2
Ferroptosis‐Related Gene SAT1 Contributes to Immune Responses in Acute Pancreatitis	2
Functional analysis of hepatic long non‐coding ribonucleic acids during liver transplantation in humans	2
Molecular Crosstalk Between Osteoporosis and Osteosarcoma: Identification of Common Diagnostic Markers and Therapeutic Targets	2
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BRIX1 promotes ribosome synthesis and enhances glycolysis by selected translation of GLUT1 in colorectal cancer	2
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Single‐cell RNA‐sequencing analysis reveals divergent transcriptome events between platinum‐sensitive and platinum‐resistant high‐grade serous ovarian carcinoma	2
Single‐cell transcriptome analysis reveals heterogeneity of neutrophils in non‐small cell lung cancer	2
Prognostic evaluation of the novel blueprint of DNA methylation sites by integrating bulk RNA‐sequencing and methylation modification data in endometrial cancer	2