Journal of Gene Medicine

Article	Citations
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Long non‐coding RNA SNHG1 activates glycolysis to promote hepatocellular cancer progression through the miR‐326/PKM2 axis	42
Hyperfunction variant rs708035 of interleukin 1 receptor‐associated kinases 2 gene involved in the predisposition of leprosy infection	41
Identification of module genes and functional pathway analysis in septic shock subtypes by integrated bioinformatics analysis	27
Withdrawn: Z.Cui, Q.Sun, W.Yan, Q.Han, G.Wang, Y.Hu. The role of miR‐320a and its target gene GMEB1 in epithelial‐mesenchymal transition and invasion of colorectal cancer, published in The Journal of	26
Withdrawn: X.Chen, Y.Li, M.Zhang, X.Wu, J.Zhu. Silencing LCK inactivates the NF‐κB pathway to attenuate cartilage injury in osteoarthritis: An in vivo and in vitro study, published in Th	23
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Diverse cell death patterns‐related signature for predicting prognosis and drug sensitivity of osteosarcoma patients	22
Downregulated expression of plakophilin‐2 gene in patients with colon adenocarcinoma predicts an unfavorable prognosis and immune infiltrate	22
Lnc00113 promotes triple‐negative breast cancer progression via the NOB‐1/MAPK signaling axis	21
WES and Transcriptome Analysis Identifies FN1 as a Candidate Gene for Anterior Segment Dysgenesis	21
Application of CAR‐T cell technology in autoimmune diseases and human immunodeficiency virus infection treatment	20
Interaction Between YTH Domain‐Containing Family Protein 2 and SET Domain‐Containing Lysine Methyltransferase 7 Suppresses Autophagy in Osteoarthritis Chondrocytes, Exacerbating Cartilage Damage	19
Haplotype analysis and linkage disequilibrium of ApoB gene polymorphisms and its relationship with hyperlipidemia in patients with acne vulgaris	19
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Adenovirus VA RNAs impair maturation of primary microRNA	18
Autophagy‐related risk signature based on CDNK2A to facilitate survival prediction of patients with endometrial cancer	17
LINC01291 promotes hepatocellular carcinoma development by targeting the miR‐186‐5p/OXSR1 axis	17
Downregulation of indolethylamine N‐methyltransferase is an early event in the rat hepatocarcinogenesis and is associated with poor prognosis in hepatocellular carcinoma patients	17
Constructing and validating a risk model based on neutrophil‐related genes for evaluating prognosis and guiding immunotherapy in colon cancer	17
Interleukin‐17A educated hepatic stellate cells promote hepatocellular carcinoma occurrence through fibroblast activation protein expression	17
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Antigen processing and presentation‐related signature‐derived BNIP3 is a novel oncogene and immunotherapy determinant in osteosarcoma based on machine learning and in vitro validation	16
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Integrative analysis of an endoplasmic reticulum stress‐related signature in multiple myeloma	14
FOXA3: A Novel Tumor Suppressor in Esophageal Squamous Cell Carcinoma	14
Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia	13
Integrated mRNA and microRNA profiling in lung tissue and blood from human silicosis	13
Bone marrow overexpression of SNAI1 is an early indicator of intrinsic drug resistance in patients with de novo acute myeloid leukemia	13
Studying the mechanism underlying lipid metabolism in osteosarcoma based on transcriptomic RNA sequencing and single‐cell data	13
Expression and prognostic value of cell‐cycle‐associated genes in lung squamous cell carcinoma	13
Activation of toll‐like receptor 4/nuclear factor‐kappa B signaling by triggering a receptor expressed on myeloid cells 1 promotes alveolar macrophage M1 polarization and exacerbates septic acute lung	12
Pharmacogenomic evaluation of CYP2C19 alleles linking low clopidogrel response and the risk of acute coronary syndrome in Indians	12
A novel anoikis‐related prognostic signature associated with prognosis and immune infiltration landscape in lung adenocarcinoma	12
circANKRD28 inhibits cisplatin resistance in non‐small‐cell lung cancer through the miR‐221‐3p/SOCS3 axis	12
Anisomycin inhibits the activity of human ovarian cancer stem cells via regulating antisense RNA NCBP2‐AS2/MEK/ERK/STAT3 signaling	12
Successful liver transduction by re‐administration of different adeno‐associated virus vector serotypes in mice	12
lncRNA MALAT1 promotes osteogenic differentiation through the miR‐217/AKT3 axis: A possible strategy to alleviate osteoporosis	12
Identification of SGMS2 as a molecule involved in natural killer cell recruitment and its in‐deep analysis in the liver cancer microenvironment: Evidence from large populations cohort	11
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Construction and validation of risk model of EMT‐related prognostic genes for kidney renal clear cell carcinoma	11
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A combined diagnostic model based on circulating tumor cell in patients with solitary pulmonary nodules	10
Exploration of YBX1 role in the prognostic value and immune characteristics by single‐cell and bulk sequencing analysis for liver hepatocellular carcinoma	10
Noninvasive detection of fetal genetic variations through polymorphic site sequencing of maternal plasma DNA	10
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Genetically predicted blood metabolites mediate the association between circulating immune cells and pancreatic cancer: A Mendelian randomization study	9
Insights into the heterogeneity of the tumor microenvironment in lung adenocarcinoma and squamous carcinoma through single‐cell transcriptomic analysis: Implications for distinct immunotherapy outcome	9
Homozygous missense variant in POPDC3 causes recessive limb‐girdle muscular dystrophy type 26	9
Genomic instability‐associated two‐miRNA signature as a novel prognostic biomarker in breast cancer	9
Sequence variants in the BTD underlying biotinidase deficiency in families of Pakistani origin	9
A variant in sperm‐specific glycolytic enzyme enolase 4 (ENO4) causes human male infertility	9
Cis‐regulation of antisense non‐coding RNA at the JAZF1 locus in type 2 diabetes	9
Comprehensive profiling of endocrine metabolism identifies a novel signature with robust predictive value in ovarian cancer	9
FPPS Downregulation Attenuates Endoplasmic Reticulum Stress in Pulmonary Epithelial Cells	9
Non‐coding RNAs are correlated to TGF‐β receptor type 2 in patients with colorectal cancer	9
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Development of an ubiquitin‐proteasome system signature for predicting prognosis and providing therapeutic guidance for patients with triple‐negative breast cancer	8
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Implantation of human urine stem cells promotes neural repair in spinal cord injury rats associated cadeharin‐1 and integrin subunit beta 1 expression	8
FN1 and cancer‐associated fibroblasts markers influence immune microenvironment in clear cell renal cell carcinoma	8
Silencing N29 Regulated miR‐193b‐5p/TGFBR2 Axis to Mitigate the Progression of Cardiac Hypertrophy	8
JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial–mesenchymal transition in lung adenocarcinoma	8
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Mechanism of Tourette Syndrome Induced by ABGA‐Mediated CaMKII‐TH Pathway	7
Development of the prognostic value in lung adenocarcinoma based on anoikis‐related genes and initial experimental validation	7
Prenatal diagnosis of Walker–Warburg syndrome due to compound mutations in the B3GALNT2 gene	7
Identification of prognostic value of anoikis‐related gene score model combined with tumor microenvironment score models in esophageal squamous cell carcinoma	7
Machine learning reveals PANoptosis as a potential reporter and prognostic revealer of tumour microenvironment in lung adenocarcinoma	7
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Silencing of circDPP4 suppresses cell progression of human prostate cancer and enhances docetaxel cytotoxicity through regulating the miR‐564/ZIC2 axis	7
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Insights Into the Dysfunctional Communication Switches Targeting Osteocyte Mechanotransduction and Lacunar–Canalicular Gene Network in Pathogenesis of Osteoarthritis	7
A comprehensive study of oxidative stress‐related effects on the prognosis and drug therapy of cervical cancer	7
Biocompatible hydroxyapatite‐based nano vehicle bypasses viral transduction and enables sustained silencing of a pluripotency marker gene, demonstrating desired differentiation in mouse embryonic stem	7
Circulating plasma miR222‐3P status and its potential diagnostic performance in prostate cancer	7
Bioinformatics‐based analysis of programmed cell death pathway and key prognostic genes in gastric cancer: Implications for the development of therapeutics	6
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Characterization of the evolution trajectory and immune profiling of new histologic patterns in lung adenocarcinoma	6
A novel compound heterozygous variant linked to hematuria in a family with hereditary factor VII deficiency	6
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Exploring the Protein–Metabolite Interplay to Discover Novel Drug Targets for Alzheimer's Disease	6
lncRNA OIP5‐AS1 knockdown or miR‐223 overexpression can alleviate LPS‐induced ALI/ARDS by interfering with miR‐223/NLRP3‐mediated pyroptosis	6
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Idiopathic Pulmonary Fibrosis Is Associated With Type 1 Diabetes: A Two‐Sample Mendelian Randomization Study	6
The profile of cytokines against bacterial infection in dental pulp	6
Anti‐Glutamic Acid Decarboxylase 65 (GAD65) Antibodies and Neurological Syndromes	6
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Reappraising the role of chronic inflammatory burden in heart failure	6
Reducing the transcriptional read‐through rate of a lentiviral vector for β‐thalassemia gene therapy	6
A novel variant of C12orf4 linked to autosomal recessive intellectual disability type 66 with phenotype expansion	6
Novel algorithm for diagnosis of Arrhythmogenic cardiomyopathy and dilated cardiomyopathy: Key gene expression profiling using machine learning	6
sRNA21, a novel small RNA, protects Mycobacterium abscessus against oxidative stress	5
Histidine‐enhanced gene delivery systems: The state of the art	5
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Novel molecular insights into pyroptosis in triple‐negative breast cancer prognosis and immunotherapy	5
Integrated transcriptome, proteome and single‐cell sequencing uncover the prognostic and immunological features of colony‐stimulating factor 3 receptor in pan‐cancer	5
Metabolism‐related gene vaccines and immune infiltration in ovarian cancer: A novel risk score model of machine learning	5
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Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR‐217	5
Leveraging human–mouse studies to advance the genetics of hearing impairment in Africa	5
Homologous recombination repair gene‐based risk model predicts prognosis and immune microenvironment for primary lung cancer after previous malignancies	5
Long non‐coding RNA linc00659 promotes tumour progression by regulating FZD6/Wnt/β‐catenin signalling pathway in colorectal cancer via m6A reader IGF2BP1	5
Marked increase in tumor transfection with a truncated branched polymer	5
Hsa_circ_0003596 enhances the development of cell renal clear cell carcinoma through the miR‐502‐5p/IGF1/PI3K/AKT axis	5
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USP18 promotes colon adenocarcinoma progression via targeting the ERK‐MNK signaling pathway	5
Identification and characterization of RAC1‐related immune and prognostic subtypes of hepatocellular carcinoma	5
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Inhibition of HIST1H2AB suppresses the proliferation of lung adenocarcinoma	5
Three molecular subtypes and a five‐gene signature for hepatocellular carcinoma based on m7G‐related classification	5
The inflammatory response‐related robust machine learning signature in endometrial cancer: Based on multi‐cohort studies	5
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Baicalin induces ferroptosis in oral squamous cell carcinoma by suppressing the activity of FTH1	4
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Network pharmacology and bioinformatics analysis on the underlying mechanisms of baicalein against oral squamous cell carcinoma	4
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Characterization of Immune Landscape Based on Homologous Recombination Deficiency Associated Signatures and Identification of Knockdown of ERCC6L to Promote Radiosensitivity in Breast Cancer	4
Claudin‐1, a Biomarker of Epithelial‐Mesenchymal Transformation, Enhances Lipid Metabolism in Colorectal Cancer Cells to Promote Tumor Metastasis	4
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OMICRON: Virology, immunopathogenesis, and laboratory diagnosis	4
Enhancement of adeno‐associated virus serotype 6 transduction into T cells with cell‐penetrating peptides	4
Identification and exploration of aging‐related subtypes and distinctive role of SERPINE1 in heart failure based on single‐cell and bulk RNA sequencing data	4
MYC‐activated LINC00607 promotes hepatocellular carcinoma progression by regulating the miR‐584‐3p/ROCK1 axis	4
Retraction: Bladder cancer‐associated transcript 2 contributes to nephroblastoma progression	4
Apoptosis pathways and osteoporosis: An approach to genomic analysis	4
Anoikis‐related signature in liver hepatocellular carcinoma defines the YBX1/SPP1 axis by machine learning strategies and valid experiments	4
In Silico Analysis of Novel circRNA‐miRNA‐mRNA Axis in BRAFV600E Melanoma: Implications for Primary to Metastasis Transformation and TIME Modulation	4
Multi‐Omics Integrated Analysis of the Protective Effect of Tertiary Lymphoid Structures and Associated Key Regulatory Genes in Human Gallbladder Cancer	4
ANKRD37 inhibits trophoblast migration and invasion by regulating the NF‐κB pathway in preeclampsia	4
A signature based on neutrophil extracellular trap‐related genes for the assessment of prognosis, immunoinfiltration, mutation and therapeutic response in hepatocellular carcinoma	4
Inhibition of AHNAK nucleoprotein 2 alleviates pulmonary fibrosis by downregulating the TGF‐β1/Smad3 signaling pathway	4
Intramyocardial adenoviral vascular endothelial growth factor‐D∆N∆C gene therapy does not induce ventricular arrhythmias	4
Association between polymorphisms of ABCB1 and prognosis in esophageal squamous cell carcinoma patients treated with taxane	4
Exploring Potential Hub Genes and Molecular Mechanisms Linking Cardia Carcinoma With Sjögren's Syndrome Based on Comprehensive Bioinformatics Analysis and Machine Learning	4
A Treg‐related riskscore model may improve the prognosis evaluation of colorectal cancer	4
Early distribution of18 F‐labeled AAV9 vectors in the cerebrospinal fluid after intracerebroventricular or intracisternal magna infusion in non‐human primates	4
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Necrotizing apoptosis‐related genes prognosis and treatment effect analysis of osteosarcoma in children	4
Comprehensive transcriptomic analysis and machine learning reveal unique gene expression profiles in patients with immune‐mediated necrotizing myopathy	4
Extracellular vesicles from bone marrow mesenchymal stem cells alleviate acute rejection injury after liver transplantation by carrying miR‐22‐3p and inducing M2 polarization of Kupffer cells	4
miR‐4286 promotes prostate cancer progression by targeting the expression of SALL1	4
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Peroxisome proliferator‐activated receptors signature reveal the head and neck squamous cell carcinoma energy metabolism phenotype and clinical outcome	3

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Circular RNA HIPK3 facilitates ferroptosis in gestational diabetes mellitus by regulating glutathione peroxidase 4 DNA methylation	3
Dipeptidyl peptidase 4: A predictor of ferroptosis in ulcerative colitis	3
MEG3 shuttled by exosomes released from human bone marrow mesenchymal stem cells promotes TP53 stability to regulate MCM5 transcription in keloid fibroblasts	3
Impact of ABCB1, ABCC1, ABCC2, and ABCG2 variants in predicting prognosis and clinical outcomes of north Indian lung cancer patients undergoing platinum‐based doublet chemo	3
Exploring the interplay between bisphenol A exposure, the immune microenvironment and hepatocellular carcinoma progression	3
DSCC1 as a Novel Biomarker in Hepatocellular Carcinoma: Diagnostic Potential, Prognostic Impact, Correlation With Key Pathways, and Association With the Immune Landscape	3
Impact of inflammatory cytokine and adipokine gene variations in the development of HIV‐associated lipodystrophy	3
Single‐cell sequencing reveals the correlation of aggrephagy signaling and multiple myeloma immune microenvironment composition	3
Long non‐coding RNA LGALS8‐AS1 facilitates PLAGL2‐mediated malignant phenotypes in gastric cancer	3
Genome wide analysis of dexamethasone stimulated mineralization in human dental pulp cells by RNA sequencing	3
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO‐1 Pathways	3
Function and prognostic value of N6‐methyladenosine‐modified RNAs in lung adenocarcinoma	3
Zebrafish in understanding molecular pathophysiology, disease modeling, and developing effective treatments for Rett syndrome	3
M2 macrophage marker CHI3L2 could serve as a potential prognostic and immunological biomarker in glioma by integrated single‐cell and bulk RNA‐Seq analysis	3
Viral and non‐viral gene therapy using 3D (bio)printing	3
Metabolic and immune‐related gene signatures: Predictive stratification and prognostic implications in gastric cancer	3
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AKT/FOXM1/STMN1 signaling pathway activation by SMC1A promotes tumor growth in breast cancer	3
GRIK1‐AS1 deficiency accelerates endometriosis progression by boosting DNMT1‐dependent SFRP1 promoter methylation in endometrial stromal cells	3
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Combination therapy with chitosan/siRNA nanoplexes targeting PDGF‐D and PDGFR‐β reveals anticancer effect in breast cancer	3
Development of a novel prognostic signature based on single‐cell combined bulk RNA analysis in breast cancer	3
Sp2 Transcription Factor Alleviates Chondrocyte Loss in Osteoarthritis by Repressing the DVL1‐Dependent Wnt/β‐Catenin Signaling Pathway	3
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Age‐related genes USP2 and ARG2 are involved in the reduction of immune cell infiltration in elderly patients with rheumatoid arthritis	3
Icariside II in NSCLC and COVID‐19: Network pharmacology and molecular docking study	3
RNA sequencing and bioinformatics analysis revealed PACSIN3 as a potential novel biomarker for platinum resistance in epithelial ovarian cancer	3
Cytotoxic T‐lymphocytes in acute myeloid leukemia: Monitoring prognosis and guiding treatment choice	3
Leveraging SEER data through machine learning to predict distant lymph node metastasis and prognosticate outcomes in hepatocellular carcinoma patients	3
Withdrawn: L.Xuan, Z.Sun, J.Wang, S.Gao. Long non‐coding RNA SNHG8 promotes ovarian cancer progression through serving as a sponge for miR‐1270 to regulate S100A11 expression, published in The Journal	3
Liver Enzyme Genetics and Health Conditions in East Asians: Genetic Architecture and Causal Insights	3
Methyltransferase‐like 3 modulates osteogenic differentiation of adipose‐derived stem cells in osteoporotic rats	3
Single‐cell analysis of Crohn's disease: Unveiling heterogeneity and evaluating ustekinumab outcomes	3
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Maternal ApoE genotype and risk of recurrent pregnancy loss: An updated systematic review and meta‐analysis	3
Prognostic analysis and validation of lncRNAs in bladder cancer on the basis of neutrophil extracellular traps	3
Tele‐Genetic Versus Onsite Counseling for APOE Disclosure: A 6‐Month Study of Empowerment, Psychological Distress, and Behavioral Outcomes in Cognitively Diverse Individuals	3
Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple‐vessel disease patients	3
Potentially functional genetic variants of the notch signaling pathway genes predict survival of Chinese patients with esophageal squamous cell carcinoma	3
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Exploration of s new biomarker in osteosarcoma and association with clinical outcomes: TOP2A+cancer associated fibroblasts	2
Hypoxia‐Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin‐Induced Ferroptosis in Cervical Cancer Cells	2
Integrative analysis of cuproptosis‐associated genes for predicting immunotherapy response in single‐cell and multi‐cohort studies	2
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Adoptive Transfer of T Cells as a Potential Therapeutic Approach in the Bleomycin‐Injured Mouse Lung	2
Autophagy‐related CMTM6 promotes glioblastoma progression by activating Wnt/β‐catenin pathway and acts as an onco‐immunological biomarker	2
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Pericarpium Trichosanthis Inhibits TGF‐β1‐Smad3 Pathway‐Induced Cardiac Fibrosis in Heart Failure Rats via Upregulation of microRNA‐29b	2
TaqI polymorphism T/t genotypes at the vitamin D receptor gene (VDR) are associated with increased serum vitamin D levels in mild and moderate psoriasis vulgaris: A pilot study	2
Unveiling Anoikis‐related genes: A breakthrough in the prognosis of bladder cancer	2
Single‐cell RNA‐sequencing analysis reveals divergent transcriptome events between platinum‐sensitive and platinum‐resistant high‐grade serous ovarian carcinoma	2
Circ_0073228 serves as a competitive endogenous ribonucleic acid to facilitate proliferation and inhibit apoptosis of hepatocellular carcinoma cells by the miR‐139‐5p/deoxyribonuclease II axis	2
Long noncoding RNA 02027 inhibits proliferation, migration and invasion of hepatocellular carcinoma via miR‐625‐3p/PDLIM5 pathway	2
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Circular RNA ITCH attenuates the progression of nasopharyngeal carcinoma by inducing PTEN upregulation via miR‐214	2
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RNA expression profiling in lymphoblastoid cell lines from mutated and non‐mutated amyotrophic lateral sclerosis patients	2
NLRC4‐mediated pyroptosis was involved in coagulation disorders of acute pancreatitis	2
Comparison of immune‐related gene signatures and immune infiltration features in early‐ and late‐onset preeclampsia	2
Strategic deactivation of mRNA COVID‐19 vaccines: New applications for siRNA therapy and RIBOTACs	2
The suppression of OTUD7B by miR‐491‐5p enhances the ubiquitination of VEGFA to suppress vascular mimicry in non‐small cell lung cancer	2
Clinical and prognostic significance analysis of glycolysis‐related genes in HNSCC	2
Identification of the shared gene signatures and molecular pathways in systemic lupus erythematosus and diffuse large B‐cell lymphoma	2
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The role of ABCB1 gene polymorphisms in steroid‐resistant nephrotic syndrome: Evidence from a meta‐analysis of steroid‐receiving patients	2
Prognostic evaluation of the novel blueprint of DNA methylation sites by integrating bulk RNA‐sequencing and methylation modification data in endometrial cancer	2
Integrative Analysis Identifies NSUN2 as an Essential Coordinator for Glioma Malignancy and Glucose Metabolism	2
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SYNGR2 serves as a prognostic biomarker and correlates with immune infiltrates in esophageal squamous cell carcinoma	2
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BRIX1 promotes ribosome synthesis and enhances glycolysis by selected translation of GLUT1 in colorectal cancer	2
X‐linked BCOR variants identified in Chinese Han patients with congenital heart disease	2
Genome‐wide polygenic risk score for rheumatoid arthritis prediction in postmenopausal women	2
Single‐cell transcriptome analysis reveals heterogeneity of neutrophils in non‐small cell lung cancer	2
Functional analysis of hepatic long non‐coding ribonucleic acids during liver transplantation in humans	2
From cancer big data to treatment: Artificial intelligence in cancer research	2
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