OOIR: Observatory of International Research

Papers

(The median citation count of Prostaglandins & Other Lipid Mediators is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Role of arachidonic cascade in COVID-19 infection: A review	36
Formation of lipoxins and resolvins in human leukocytes	27
20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance	25
Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration	23
Understanding the possible role of endocannabinoid system in obesity	22
Accurate identification of breast cancer margins in microenvironments of ex-vivo basal and luminal breast cancer tissues using Raman spectroscopy	22
Regulation of arachidonic acid oxidation and metabolism by lipid electrophiles	20
Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells	20
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer	18
Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders	18
Changes of tear lipid mediators after eyelid warming or thermopulsation treatment for meibomian gland dysfunction	18
Sphingolipid metabolism as a marker of hepatotoxicity in drug-induced liver injury	17
Host sphingolipids: Perspective immune adjuvant for controlling SARS-CoV-2 infection for managing COVID-19 disease	17
Lipoxin A4 promotes reduction and antibiotic efficacy against Pseudomonas aeruginosa biofilm	16
Influential role of 7-Ketocholesterol in the progression of Alzheimer’s disease	16
Circulating microRNA-126 &122 in patients with coronary artery disease: Correlation with small dense LDL	16
20-HETE-promoted cerebral blood flow autoregulation is associated with enhanced pericyte contractility	16
The function of specialized pro-resolving endogenous lipid mediators, vitamins, and other micronutrients in the control of the inflammatory processes: Possible role in patients with SARS-CoV-2 related	15
Fatty acids act on vascular endothelial cells and influence the development of cardiovascular disease	14
Improved quantification of lipid mediators in plasma and tissues by liquid chromatography tandem mass spectrometry demonstrates mouse strain specific differences	14
Diosgenin suppresses COX-2 and mPGES-1 via GR and improves LPS-induced liver injury in mouse	13
Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts	13
Intrathecal administration of Resolvin D1 and E1 decreases hyperalgesia in mice with bone cancer pain: Involvement of endocannabinoid signaling	13
Shengmai Yin formula exerts cardioprotective effects on rats with chronic heart failure via regulating Linoleic Acid metabolism	13
Aspirin attenuates the expression of adhesion molecules, risk of obesity, and adipose tissue inflammation in high-fat diet-induced obese mice	13

Role of arachidonic acid lipoxygenase pathway in Asthma	12
Involvement of prostacyclin synthase in high-fat-diet-induced obesity	12
Prostaglandin E2, 9S-, 13S-HODE and resolvin D1 are strongly associated with the post-stroke cognitive impairment	12
Stimulatory effect of docosahexaenoic acid alone or loaded in zinc oxide or silver nanoparticles on the expression of glucose transport pathway	11
Resolvin D2 promotes host defense in a 2 - hit model of sepsis with secondary lung infection	11
Prostaglandin E2 receptors and their role in gastrointestinal motility – Potential therapeutic targets	11
The role of Resolvin D1 in liver diseases	11
The role of platelets in non-alcoholic fatty liver disease: From pathophysiology to therapeutics	11
Micronized / ultramicronized palmitoylethanolamide (PEA) as natural neuroprotector against COVID-19 inflammation	10
Pomegranate seed oil and bitter melon extract supplemented in diet influence the lipid profile and intensity of peroxidation in livers of SPRD rats exposed to a chemical carcinogen	10
The effect of Conjugated Linoleic Acid intake on oxidative stress parameters and antioxidant enzymes: A systematic review and meta-analysis of randomized clinical trials	10
Linoleic acid induces secretion of extracellular vesicles from MDA-MB-231 breast cancer cells that mediate cellular processes involved with angiogenesis in HUVECs	9
EPA/DHA and linseed oil have different effects on liver and adipose tissue in rats fed with a high-fat diet	9
Effect of acyl and alkyl analogs of platelet-activating factor on inflammatory signaling	9
Intrinsic 5-lipoxygenase activity regulates migration and adherence of mantle cell lymphoma cells	8
Platelet activating factor in the eye: Physiological roles, diseases and future perspectives	8
Nonsteroidal anti-inflammatory drugs for retinal neurodegenerative diseases	8
Mechanism of thromboxane receptor-induced vasoconstriction in human saphenous vein	7
Enalapril improves obesity associated liver injury ameliorating systemic metabolic markers by modulating Angiotensin Converting Enzymes ACE/ACE2 expression in high-fat feed mice	7
Cyclooxygenase-2 contributes to diabetic nephropathy through glomerular EP4 receptor	7
The enantioselective separation and quantitation of the hydroxy-metabolites of arachidonic acid by liquid chromatography – tandem mass spectrometry	6
Post-mortem changes of prostanoid concentrations in tissues of mice: Impact of fast cervical dislocation and dissection delay	6
Profiling oxylipins released from human platelets activated through the GPVI collagen receptor	6
Duloxetine strengthens osteoblast activation by prostaglandin E1: Upregulation of p38 MAP kinase	6
DHA, RvD1, RvD5, and MaR1 reduce human coronary arteries contractions induced by PGE2	5
Pomegranate seed oil mitigates liver and kidney damage in an experimental colitis model: Modulation of NF-κB activation and apoptosis	5
Tumorigenic effect mediated by ROS/eicosanoids and their regulation on TP53 expression in a murine mammary gland adenocarcinoma	5
Role of cyclooxygenases and prostaglandins in adult brain neurogenesis	5
Pathophysiological role of prostaglandin E synthases in liver diseases	5
Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior	5
The synergistic effect of nanocurcumin and donepezil on Alzheimer's via PI3K/AKT/GSK-3β pathway modulating	5
Thromboxane-dependent coronary vasoconstriction in obese mice: Role of peroxynitrite	5
Microsomal prostaglandin E synthase-1 inhibition promotes shunting in arachidonic acid metabolism during inflammatory responses in vitro	5
Anti-inflammatory activity of 2-((3-(chloromethyl)benzoyl)oxy)benzoic acid in LPS-induced rat model	5
Clinical implications of lipid peroxides levels in plasma and tumor tissue in breast cancer patients	5
Docosahexaenoic acid inhibits ischemic stroke to reduce vascular dementia and Alzheimer’s disease	5
Formulation of wheat germ oil based on nanoemulsions to mitigate cisplatin's nephrotoxic effects	5
Sexual dimorphism in renal heme oxygenase-1 and arachidonic acid metabolizing enzymes in spontaneously hypertensive rats versus normotensive Wistar Kyoto rats	4
Divergent PGD2 and leukotriene C4 metabolite excretion following aspirin therapy: Ten patients with systemic mastocytosis	4
Exploring nitric oxide as a crucial prognostic biomarker of coronary artery disease	4
Detection and quantification of prostaglandin E2 in saliva by liquid chromatography-tandem mass spectrometry using microextraction by packed sorbent	4
Prostaglandin E2 induces dual-specificity phosphatase-1, thereby attenuating inflammatory genes expression in human osteoarthritic synovial fibroblasts	4
Loss of lysophosphatidic acid receptor 1 in hepatocytes reduces steatosis via down-regulation of CD36	4
The effect of SARS-CoV-2 variants on the plasma oxylipins and PUFAs of COVID-19 patients	4
Cross-talk between bioactive lipid mediators and the unfolded protein response in ischemic stroke	4
Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana	4
Specialized pro-resolving lipid mediators and resolution of viral diseases	4
Lipoxin and glycation in SREBP signaling: Insight into diabetic cardiomyopathy and associated lipotoxicity	4
Eicosanoid production by macrophages during inflammation depends on the M1/M2 phenotype	4
12-HETE activates Müller glial cells: The potential role of GPR31 and miR-29	4

Altered mucosal and plasma polyunsaturated fatty acids, oxylipins, and endocannabinoids profiles in Crohn’s disease	4
17-(R/S)-hydroxyeicosatetraenoic acid (HETE) induces cardiac hypertrophy through the CYP1B1 in enantioselective manners	4
Physical exercise regulates apoptosis and prostatic inflammatory effects induced by high-fat diet in PPAR-alpha deleted mice	4
Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells	4
Imbalanced serum levels of resolvin E1 (RvE1) and leukotriene B4 (LTB4) may contribute to the pathogenesis of atherosclerosis	4
Elabela relaxes rat pulmonary artery and trachea via BKCa, KV, and KATP channels	3
Effects of Lactobacillus acidophilus administration to anorexigenic neuropeptides and some biochemical parameters on rats fed with a high-fat diet	3
Individual resolvin E family members work distinctly and in a coordinated manner in the resolution of inflammation	3
Effect of CLA supplementation on factors related to vascular dysfunction in arteries of orchidectomized rats	3
Preparation of pumpkin oil-based nanoemulsion as a potential estrogen replacement therapy to alleviate neural-immune interactions in an experimental postmenopausal model	3
The association between total cholesterol and cognitive impairment in chronic obstructive pulmonary disease patients	3
Metabolism and biological functions of 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid	3
Rosa damascena Miller essential oil relaxes rat trachea via KV channels, KATP channels, and BKCa channels	3
A single extraction 96-well method for LC-MS/MS quantification of urinary eicosanoids, steroids and drugs	3
Plasma oxylipin profiles reflect Parkinson's disease stage	3
Evaluation of inhibitors of the arachidonic acid cascade with intact platelets using an on-line dilution and on-line solid phase extraction HPLC–MS method	3
Lipid mediated brain disorders: A perspective	3
Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet	3
Conjugated linoleic acid strengthens the apoptotic effect of cisplatin in A549 cells	3
Trisomy 21 impairs PGE2 production in dermal fibroblasts	3
12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets	3
Role of sphingosine-1-phosphate mediated signalling in systemic lupus erythematosus	3
Moringa oleifera leaves extract loaded gold nanoparticles offers a promising approach in protecting against experimental nephrotoxicity	3
Anti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells stimulated by cigarette smoke extract	2
The analysis of fatty acids and their derivatives in the liver of C57BL/6 mice with long-term caloric restrictions	2
Prostaglandin D2 regulates Escherichia coli-induced inflammatory responses through TLR2, TLR4, and NLRP3 in macrophages	2
Activation of phospholipase A2 by prostaglandin in vitro	2
An updated review of the effects of eicosapentaenoic acid- and docosahexaenoic acid-derived resolvins on bone preservation	2
Protective effect of misoprostol against paclitaxel-induced cardiac damage in rats	2
Leukotriene receptor antagonism with montelukast as a possible therapeutic for venous thromboembolism prophylaxis: An observational study	2
Sphingolipidomic profile and HDL subfractions in obese dyslipidemic type 2 diabetic patients	2
Changes in the level of cytokines in the saliva of hypertensive patients with chronic periodontitis after scaling and root planning	2
20-HETE downregulates Na/K-ATPase α1 expression via the ubiquitination pathway	2
The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms	2
Lipoxin A4 inhibits the development of endometriosis in a mouse model by suppressing local estradiol synthesis	2
The biosynthetic pathways of the protectins	2
Modulations of urinary lipid mediators in acute bladder cystitis	2
FBXO31 suppresses lipogenesis and tumor progression in glioma by promoting ubiquitination and degradation of CD147	2
Prostaglandin E2/Leukotriene B4 balance and viral load in distinct clinical stages of COVID-19: A cross-sectional study	2
A paracrine effect of 15 (S)-hydroxyeicosatetraenoic acid revealed in prostaglandin production by human follicular dendritic cell-like cells	2
The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells	2
N-glycosylation modifies prostaglandin E2 uptake by reducing cell surface expression of SLCO2A1	2
ANTI-INFLAMMATORY AND MOLECULAR DOCKING ANALYSIS OF LEUCAS VESTITA Wall. Ex. Benth. EXTRACT AGAINST CYCLO-OXYGENASE-2	2
Effects of 15-lipoxygenase overexpressing adipose tissue mesenchymal stem cells on the Th17 / Treg plasticity	2
Exploring the role of polyunsaturated fatty acid ratios in modulating neuroinflammation in LPS-induced microglia: A comprehensive in vitro analysis	2
The frequency of cytochrome 4F2 rs2108622 genetic variant and its effects on the lipid profile and complications of type II diabetes among a sample of patients in Jordan: A pilot study	2
A synthetic prostaglandin E1 analogue, misoprostol, ameliorates paclitaxel-induced oxidative damage in rat brain	2
Prevention of nephrotoxicity induced by amikacin: The role of misoprostol, A prostaglandin E1 analogue	2
Set up and validation of a sensitive method to quantify prostaglandins, prostaglandin-glycerol esters and prostaglandin-ethanolamides, as well as their respective precursors	2
Functional and pathological role of 15-Lipoxygenase and its metabolites in pregnancy and pregnancy-associated complications	2
Rosa damascena Miller essential oil relaxes rat thoracic aorta through the NO-cGMP-dependent pathway	2
Effect of calcium hydroxide alone or in combination with ibuprofen and ciprofloxacin on postoperative pain and periapical prostaglandin E2 level: A randomized clinical study	2