OOIR: Observatory of International Research

Papers

(The median citation count of Prostaglandins & Other Lipid Mediators is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Oxysterols as lipid mediators: Their biosynthetic genes, enzymes and metabolites	44
A review on mPGES-1 inhibitors: From preclinical studies to clinical applications	41
A journey of celecoxib from pain to cancer	35
Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases	32
Role of arachidonic cascade in COVID-19 infection: A review	32
Cytochrome P450-derived eicosanoids and inflammation in liver diseases	25
Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes	24
The chemistry, biology and pharmacology of the cyclopentenone prostaglandins	23
20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance	22
Role of cytochrome P450-derived, polyunsaturated fatty acid mediators in diabetes and the metabolic syndrome	22
Understanding the possible role of endocannabinoid system in obesity	21
Sphingosine 1-phosphate signaling in ischemia and reperfusion injury	20
An overview of lipoxygenase inhibitors with approach of in vivo studies	19
Accurate identification of breast cancer margins in microenvironments of ex-vivo basal and luminal breast cancer tissues using Raman spectroscopy	18
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer	17
Dual soluble epoxide hydrolase inhibitor/PPAR-γ agonist attenuates renal fibrosis	17
Licofelone, a potent COX/5-LOX inhibitor and a novel option for treatment of neurological disorders	17
Host sphingolipids: Perspective immune adjuvant for controlling SARS-CoV-2 infection for managing COVID-19 disease	16
Influential role of 7-Ketocholesterol in the progression of Alzheimer’s disease	16
Regulation of arachidonic acid oxidation and metabolism by lipid electrophiles	15
Relevance of seminal F2-dihomo-IsoPs, F2-IsoPs and F4-NeuroPs in idiopathic infertility and varicocele	15
A combination of LCPUFAs regulates the expression of miRNA-146a-5p in a murine asthma model and human alveolar cells	15
Lipoxin A4 promotes reduction and antibiotic efficacy against Pseudomonas aeruginosa biofilm	14
Formation of lipoxins and resolvins in human leukocytes	14
Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells	13

Dysregulated metabolism of polyunsaturated fatty acids in eosinophilic allergic diseases	13
The function of specialized pro-resolving endogenous lipid mediators, vitamins, and other micronutrients in the control of the inflammatory processes: Possible role in patients with SARS-CoV-2 related	13
Prostaglandin E2 as a therapeutic target in bladder cancer: From basic science to clinical trials	12
Intrathecal administration of Resolvin D1 and E1 decreases hyperalgesia in mice with bone cancer pain: Involvement of endocannabinoid signaling	12
20-HETE-promoted cerebral blood flow autoregulation is associated with enhanced pericyte contractility	12
Sphingolipid metabolism as a marker of hepatotoxicity in drug-induced liver injury	12
Aspirin attenuates the expression of adhesion molecules, risk of obesity, and adipose tissue inflammation in high-fat diet-induced obese mice	12
Improved quantification of lipid mediators in plasma and tissues by liquid chromatography tandem mass spectrometry demonstrates mouse strain specific differences	12
Changes of tear lipid mediators after eyelid warming or thermopulsation treatment for meibomian gland dysfunction	12
20-hydroxyeicosatetraenoic acid alters endothelial cell barrier integrity independent of oxidative stress and cell death	11
Diosgenin suppresses COX-2 and mPGES-1 via GR and improves LPS-induced liver injury in mouse	11
Circulating microRNA-126 &122 in patients with coronary artery disease: Correlation with small dense LDL	11
Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration	11
Involvement of prostacyclin synthase in high-fat-diet-induced obesity	10
Linoleic acid induces secretion of extracellular vesicles from MDA-MB-231 breast cancer cells that mediate cellular processes involved with angiogenesis in HUVECs	10
Shengmai Yin formula exerts cardioprotective effects on rats with chronic heart failure via regulating Linoleic Acid metabolism	10
Prostaglandin E2, 9S-, 13S-HODE and resolvin D1 are strongly associated with the post-stroke cognitive impairment	10
Prostaglandin E2 receptors and their role in gastrointestinal motility – Potential therapeutic targets	10
Effect of acyl and alkyl analogs of platelet-activating factor on inflammatory signaling	9
Synthesis and function of fatty acids and oxylipins, with a focus on Caenorhabditis elegans	9
Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts	9
Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease	9
Gamma-Linolenic acid alters migration, proliferation and apoptosis in human and rat glioblastoma cells	9
EPA/DHA and linseed oil have different effects on liver and adipose tissue in rats fed with a high-fat diet	9
Therapeutic approaches to diabetic cardiomyopathy: Targeting the antioxidant pathway	9
Role of sphingolipids in the pathogenesis of intrahepatic cholestasis	9
Parasitic load determination by differential expressions of 5-lipoxygenase and PGE2 synthases in visceral leishmaniasis	8
The role of Resolvin D1 in liver diseases	8
Micronized / ultramicronized palmitoylethanolamide (PEA) as natural neuroprotector against COVID-19 inflammation	8
Aloe emodin shows high affinity to active site and low affinity to two other sites to result consummately reduced inhibition of lipoxygenase	8
Role of arachidonic acid lipoxygenase pathway in Asthma	8
Stimulatory effect of docosahexaenoic acid alone or loaded in zinc oxide or silver nanoparticles on the expression of glucose transport pathway	7
Effects of antiemetic doses of dexamethasone on plasma mediators of inflammation resolution and pain after surgery in women	7
Assessment of soluble epoxide hydrolase activity in vivo: A metabolomic approach	7
Cyclooxygenase-2 contributes to diabetic nephropathy through glomerular EP4 receptor	7
Fatty acids act on vascular endothelial cells and influence the development of cardiovascular disease	7
Cd36 gene expression in adipose and hepatic tissue mediates the lipids accumulation in liver of obese rats with sucrose-induced hepatic steatosis	7
Pomegranate seed oil and bitter melon extract supplemented in diet influence the lipid profile and intensity of peroxidation in livers of SPRD rats exposed to a chemical carcinogen	6
Sphingosine kinase 1 is required for myristate-induced TNFα expression in intestinal epithelial cells	6
Mechanism of thromboxane receptor-induced vasoconstriction in human saphenous vein	6
Nonsteroidal anti-inflammatory drugs for retinal neurodegenerative diseases	6
Resolvin D2 promotes host defense in a 2 - hit model of sepsis with secondary lung infection	6
Intrinsic 5-lipoxygenase activity regulates migration and adherence of mantle cell lymphoma cells	5
Profiling oxylipins released from human platelets activated through the GPVI collagen receptor	5
Duloxetine strengthens osteoblast activation by prostaglandin E1: Upregulation of p38 MAP kinase	5
Post-mortem changes of prostanoid concentrations in tissues of mice: Impact of fast cervical dislocation and dissection delay	5
Platelet activating factor in the eye: Physiological roles, diseases and future perspectives	5
Role of epoxyeicosatrienoic acids in the lung	5
Lipidomic profiling analysis of the phospholipid molecules in SCAP-induced lipid droplet formation in bovine mammary epithelial cells	5
The role of platelets in non-alcoholic fatty liver disease: From pathophysiology to therapeutics	5

Formulation of wheat germ oil based on nanoemulsions to mitigate cisplatin's nephrotoxic effects	5
Anti-inflammatory activity of 2-((3-(chloromethyl)benzoyl)oxy)benzoic acid in LPS-induced rat model	5
Enalapril improves obesity associated liver injury ameliorating systemic metabolic markers by modulating Angiotensin Converting Enzymes ACE/ACE2 expression in high-fat feed mice	5
Role of cyclooxygenases and prostaglandins in adult brain neurogenesis	5
The COX-2 inhibitor NS398 selectively sensitizes hypoxic HeLa cells to ionising radiation by mechanisms both dependent and independent of COX-2	5
14,15-EET involved in the development of diabetic cardiac hypertrophy mediated by PPARs	4
Cycloarta-23-ene-3beta,25-diol a pentacyclic steroid from Euphorbia spinidens, as COX inhibitor with molecular docking, and in vivo study of its analgesic and anti-inflammatory activities in male swis	4
Pathophysiological role of prostaglandin E synthases in liver diseases	4
The effect of Conjugated Linoleic Acid intake on oxidative stress parameters and antioxidant enzymes: A systematic review and meta-analysis of randomized clinical trials	4
Prostaglandin E2 induces dual-specificity phosphatase-1, thereby attenuating inflammatory genes expression in human osteoarthritic synovial fibroblasts	4
Evaluation of the pharmacokinetics of 2-carba-cyclic phosphatidic acid by liquid chromatography-triple quadrupole mass spectrometry	4
Lipoxin A4 reduces house dust mite and TNFα-induced hyperreactivity in the mouse trachea	4
Tumorigenic effect mediated by ROS/eicosanoids and their regulation on TP53 expression in a murine mammary gland adenocarcinoma	4
Thromboxane-dependent coronary vasoconstriction in obese mice: Role of peroxynitrite	4
Exploring nitric oxide as a crucial prognostic biomarker of coronary artery disease	4
Clinical implications of lipid peroxides levels in plasma and tumor tissue in breast cancer patients	4
A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage	4
Eicosanoid production by macrophages during inflammation depends on the M1/M2 phenotype	3
The enantioselective separation and quantitation of the hydroxy-metabolites of arachidonic acid by liquid chromatography – tandem mass spectrometry	3
Role of sphingosine-1-phosphate mediated signalling in systemic lupus erythematosus	3
Detection and quantification of prostaglandin E2 in saliva by liquid chromatography-tandem mass spectrometry using microextraction by packed sorbent	3
Loss of lysophosphatidic acid receptor 1 in hepatocytes reduces steatosis via down-regulation of CD36	3
Sexual dimorphism in renal heme oxygenase-1 and arachidonic acid metabolizing enzymes in spontaneously hypertensive rats versus normotensive Wistar Kyoto rats	3
The impact of Dl-3-n-butylphthalide on the lipidomics of the hippocampus in a rat model of lipopolysaccharide-induced depression	3
Physical exercise regulates apoptosis and prostatic inflammatory effects induced by high-fat diet in PPAR-alpha deleted mice	3
Metabolism and biological functions of 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid	3
Docosahexaenoic acid inhibits ischemic stroke to reduce vascular dementia and Alzheimer’s disease	3
Divergent PGD2 and leukotriene C4 metabolite excretion following aspirin therapy: Ten patients with systemic mastocytosis	3
Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana	3
Seasonal expressions of prostaglandin E synthases and receptors in the prostate of the wild ground squirrel (Spermophilus dauricus)	3
Elabela relaxes rat pulmonary artery and trachea via BKCa, KV, and KATP channels	3
Lipocalin-type Prostaglandin D2 Synthase appears to function as a Novel Adipokine Preventing Adipose Dysfunction in response to a High Fat Diet	3
A paracrine effect of 15 (S)-hydroxyeicosatetraenoic acid revealed in prostaglandin production by human follicular dendritic cell-like cells	2
Evaluation of inhibitors of the arachidonic acid cascade with intact platelets using an on-line dilution and on-line solid phase extraction HPLC–MS method	2
20-HETE downregulates Na/K-ATPase α1 expression via the ubiquitination pathway	2
Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells	2
Lipoxin A4 inhibits the development of endometriosis in a mouse model by suppressing local estradiol synthesis	2
An updated review of the effects of eicosapentaenoic acid- and docosahexaenoic acid-derived resolvins on bone preservation	2
Activation of phospholipase A2 by prostaglandin in vitro	2
Functional and pathological role of 15-Lipoxygenase and its metabolites in pregnancy and pregnancy-associated complications	2
ANTI-INFLAMMATORY AND MOLECULAR DOCKING ANALYSIS OF LEUCAS VESTITA Wall. Ex. Benth. EXTRACT AGAINST CYCLO-OXYGENASE-2	2
Effect of CLA supplementation on factors related to vascular dysfunction in arteries of orchidectomized rats	2
Exploring the role of polyunsaturated fatty acid ratios in modulating neuroinflammation in LPS-induced microglia: A comprehensive in vitro analysis	2
Gonadal function protects against organ culture-induced vascular damage. Involvement of prostanoids	2
Individual resolvin E family members work distinctly and in a coordinated manner in the resolution of inflammation	2
A synthetic prostaglandin E1 analogue, misoprostol, ameliorates paclitaxel-induced oxidative damage in rat brain	2
Microsomal prostaglandin E synthase-1 inhibition promotes shunting in arachidonic acid metabolism during inflammatory responses in vitro	2
Sphingolipidomic profile and HDL subfractions in obese dyslipidemic type 2 diabetic patients	2
Effect of calcium hydroxide alone or in combination with ibuprofen and ciprofloxacin on postoperative pain and periapical prostaglandin E2 level: A randomized clinical study	2
Rosa damascena Miller essential oil relaxes rat thoracic aorta through the NO-cGMP-dependent pathway	2
Lipid mediated brain disorders: A perspective	2
Rosa damascena Miller essential oil relaxes rat trachea via KV channels, KATP channels, and BKCa channels	2
Mechanisms underlying the protective effect of leukotriene receptor antagonist montelukast against doxorubicin induced testicular injury in rats	2