Nature Neuroscience

Papers
(The TQCC of Nature Neuroscience is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Reactive astrocyte nomenclature, definitions, and future directions1018
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19855
Parameterizing neural power spectra into periodic and aperiodic components768
Synergy between amyloid-β and tau in Alzheimer’s disease539
Disease-associated astrocytes in Alzheimer’s disease and aging490
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex370
Using Bayes factor hypothesis testing in neuroscience to establish evidence of absence336
The extent and drivers of gender imbalance in neuroscience reference lists293
Topographic organization of the human subcortex unveiled with functional connectivity gradients279
Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map277
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization276
The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice271
The multiplex model of the genetics of Alzheimer’s disease269
Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons252
Neuroinflammatory astrocyte subtypes in the mouse brain252
Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice239
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques232
Considering sex as a biological variable will require a global shift in science culture230
Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia226
Revisiting the neurovascular unit222
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease217
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits211
Preservation of a remote fear memory requires new myelin formation200
An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank194
Motor learning promotes remyelination via new and surviving oligodendrocytes190
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions190
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level187
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles186
Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory176
Long-term maturation of human cortical organoids matches key early postnatal transitions176
Spatiotemporal single-cell analysis of gene expression in the mouse suprachiasmatic nucleus174
Machine translation of cortical activity to text with an encoder–decoder framework171
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys171
Brain capillary pericytes exert a substantial but slow influence on blood flow170
Microglia phagocytose myelin sheaths to modify developmental myelination167
A community-based transcriptomics classification and nomenclature of neocortical cell types164
Single-cell analysis of olfactory neurogenesis and differentiation in adult humans159
Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo158
Edge-centric functional network representations of human cerebral cortex reveal overlapping system-level architecture154
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice152
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain151
Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning150
Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons150
AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset150
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells149
Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation148
Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72146
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis146
Phase separation at the synapse144
Interplay between persistent activity and activity-silent dynamics in the prefrontal cortex underlies serial biases in working memory144
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease142
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production142
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing140
Quantifying behavior to understand the brain140
Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury135
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2134
Revealing the structure of pharmacobehavioral space through motion sequencing134
Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia131
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis129
Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits127
A genetically encoded sensor for measuring serotonin dynamics126
Acute social isolation evokes midbrain craving responses similar to hunger124
Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans124
Neural mechanisms of aggression across species124
Large-scale neural recordings call for new insights to link brain and behavior118
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction117
Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke117
Active dendritic currents gate descending cortical outputs in perception115
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence115
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer’s disease111
CNS fibroblasts form a fibrotic scar in response to immune cell infiltration111
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease110
The claustrum coordinates cortical slow-wave activity108
High-fat food biases hypothalamic and mesolimbic expression of consummatory drives107
Issues and recommendations from the OHBM COBIDAS MEEG committee for reproducible EEG and MEG research106
Recent advances in neurotechnologies with broad potential for neuroscience research106
Diversity and dynamism in the cerebellum106
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex105
Recurrent architecture for adaptive regulation of learning in the insect brain104
Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD104
Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits103
Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons102
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics102
Shared computational principles for language processing in humans and deep language models101
Transcriptomic organization of the human brain in post-traumatic stress disorder100
Identification of neural oscillations and epileptiform changes in human brain organoids100
Paraventricular nucleus CRH neurons encode stress controllability and regulate defensive behavior selection98
Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex98
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges97
Anatomically segregated basal ganglia pathways allow parallel behavioral modulation95
Prefrontal–amygdala circuits in social decision-making94
Spatial and cell type transcriptional landscape of human cerebellar development93
Challenges and future directions for representations of functional brain organization92
Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression91
A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice91
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice91
Dense neuronal reconstruction through X-ray holographic nano-tomography89
Brainstem neurons that command mammalian locomotor asymmetries88
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders88
Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer’s disease88
A prefrontal–paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice88
Wireless multilateral devices for optogenetic studies of individual and social behaviors88
Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels86
Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition86
Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks85
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble85
General anesthetics activate a potent central pain-suppression circuit in the amygdala85
Live-imaging of astrocyte morphogenesis and function in zebrafish neural circuits84
Microglia contribute to the propagation of Aβ into unaffected brain tissue84
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder84
Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents83
Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit83
Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia82
Decoding molecular and cellular heterogeneity of mouse nucleus accumbens81
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine81
Long-term self-renewing stem cells in the adult mouse hippocampus identified by intravital imaging81
A glycolytic shift in Schwann cells supports injured axons81
GABAergic signaling to astrocytes in the prefrontal cortex sustains goal-directed behaviors79
Brain proteome-wide association study implicates novel proteins in depression pathogenesis79
Prefrontal cortex exhibits multidimensional dynamic encoding during decision-making79
Synaptic vesicles transiently dock to refill release sites79
Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain78
Ultrasonic signals associated with different types of social behavior of mice78
Single-neuron projectome of mouse prefrontal cortex78
Microglial Gi-dependent dynamics regulate brain network hyperexcitability78
The neural basis of psychedelic action77
Implicit adaptation compensates for erratic explicit strategy in human motor learning76
Hippocampal neurons represent events as transferable units of experience76
Rotational dynamics reduce interference between sensory and memory representations76
Circuit and molecular architecture of a ventral hippocampal network76
Attractor dynamics gate cortical information flow during decision-making75
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine75
A shared disease-associated oligodendrocyte signature among multiple CNS pathologies74
An amygdala-to-hypothalamus circuit for social reward74
Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity73
Gene-based therapies for neurodegenerative diseases73
Mice alternate between discrete strategies during perceptual decision-making73
A synergistic core for human brain evolution and cognition73
Probing neural codes with two-photon holographic optogenetics72
RNA transport and local translation in neurodevelopmental and neurodegenerative disease72
Maternal immune activation in mice disrupts proteostasis in the fetal brain72
An investigation across 45 languages and 12 language families reveals a universal language network72
Within-group synchronization in the prefrontal cortex associates with intergroup conflict71
Cortical-like dynamics in recurrent circuits optimized for sampling-based probabilistic inference71
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies71
Modeling behaviorally relevant neural dynamics enabled by preferential subspace identification69
The role of population structure in computations through neural dynamics69
Assessing the depth of language processing in patients with disorders of consciousness69
Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders69
Tau induces PSD95–neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration68
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states67
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB67
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines67
How to establish robust brain–behavior relationships without thousands of individuals67
The basal ganglia control the detailed kinematics of learned motor skills66
The preference for sugar over sweetener depends on a gut sensor cell65
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity65
Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk65
Genetic variants associated with longitudinal changes in brain structure across the lifespan65
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing65
A role for the cortex in sleep–wake regulation65
Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice64
Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival63
The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development62
Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology61
Visual and linguistic semantic representations are aligned at the border of human visual cortex61
Medial preoptic area antagonistically mediates stress-induced anxiety and parental behavior61
Multiple convergent hypothalamus–brainstem circuits drive defensive behavior61
Conservation of brain connectivity and wiring across the mammalian class60
Cortical interneurons in autism60
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons60
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis60
CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation59
Inferences on a multidimensional social hierarchy use a grid-like code59
Four core properties of the human brain valuation system demonstrated in intracranial signals59
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines59
Periods of synchronized myelin changes shape brain function and plasticity58
Complementary contributions of non-REM and REM sleep to visual learning57
Distinct synchronization, cortical coupling and behavioral function of two basal forebrain cholinergic neuron types56
Association between real-world experiential diversity and positive affect relates to hippocampal–striatal functional connectivity56
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting56
Independent generation of sequence elements by motor cortex55
Posterior amygdala regulates sexual and aggressive behaviors in male mice55
Temporally distinct myeloid cell responses mediate damage and repair after cerebrovascular injury55
Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression-like states55
Associative and plastic thalamic signaling to the lateral amygdala controls fear behavior54
A quantitative reward prediction error signal in the ventral pallidum54
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error54
Targeted photostimulation uncovers circuit motifs supporting short-term memory54
Neural fragility as an EEG marker of the seizure onset zone54
Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotective53
Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model52
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways52
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior52
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration52
Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function52
Membrane potential dynamics underlying context-dependent sensory responses in the hippocampus52
Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis51
Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition51
Correlations enhance the behavioral readout of neural population activity in association cortex50
AHR is a Zika virus host factor and a candidate target for antiviral therapy50
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging50
Identification of early neurodegenerative pathways in progressive multiple sclerosis50
Genetically identified amygdala–striatal circuits for valence-specific behaviors50
Mesophasic organization of GABAA receptors in hippocampal inhibitory synapses49
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation49
Primate auditory prototype in the evolution of the arcuate fasciculus49
A parsimonious description of global functional brain organization in three spatiotemporal patterns49
Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation48
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement48
New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination48
Episodic memory retrieval success is associated with rapid replay of episode content48
A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis48
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life48
Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior48
Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections48
How to build a cognitive map48
Neurons detect cognitive boundaries to structure episodic memories in humans48
Synaptic plasticity as Bayesian inference47
A cortical circuit for audio-visual predictions47
Causal role for the primate superior colliculus in the computation of evidence for perceptual decisions47
Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia47
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway47
Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation47
Pain modulates dopamine neurons via a spinal–parabrachial–mesencephalic circuit46
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging46
Placental endocrine function shapes cerebellar development and social behavior46
Dynamic representations in networked neural systems46
Interneuron origin and molecular diversity in the human fetal brain46
Systematic errors in connectivity inferred from activity in strongly recurrent networks46
Cross-hemispheric gamma synchrony between prefrontal parvalbumin interneurons supports behavioral adaptation during rule shift learning46
Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics45
Sleep down state-active ID2/Nkx2.1 interneurons in the neocortex45
Baseline brain function in the preadolescents of the ABCD Study45
Deconstructing the neurobiology of cannabis use disorder45
Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor45
Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice45
Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations44
Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation44
Semantic reconstruction of continuous language from non-invasive brain recordings44
USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans43
Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia43
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration43
Thalamic subnetworks as units of function42
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