Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	472
Salty licorice taste receptor	472
Non-REM sleep substates separate old and new memories	390
Alcohol’s necessary accessory	386
Neural basis of anticipation and premature impulsive action in the frontal cortex	345
Daily feeding entrains hunger-sensing neurons	304
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	298
Computational complexity drives sustained deliberation	286
Implementation and validation of single-cell genomics experiments in neuroscience	281
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	253
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways	236
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	219
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	214
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	209
Intracellular chloride regulation mediates local sleep pressure in the cortex	207
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	199
Climbing fibers provide essential instructive signals for associative learning	198
Differential replay of reward and punishment paths predicts approach and avoidance	197
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	194
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	191
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	181
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	181
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	181
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	180
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	180

Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	176
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	170
Genetic variants associated with longitudinal changes in brain structure across the lifespan	166
Pervasive environmental chemicals impair oligodendrocyte development	165
Neurons in the caudal ventrolateral medulla mediate descending pain control	164
Guest star in OCD	162
Computational strategies for deliberative thought	161
COVID-19 and brain aging	160
Organizing principles of the prefrontal cortex from a single-neuron projectome	156
How cancer and cortex collude	148
Widespread brain–body integration during changes of arousal	146
Lessons from resilience	146
The developmental emergence of reliable cortical representations	144
A neural mechanism for conserved value computations integrating information and rewards	141
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	140
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	137
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	136
Adult-born dentate granule cells promote hippocampal population sparsity	134
Aging and injury drive neuronal senescence in the dorsal root ganglia	130
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	129
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	129
Remembering Stephen T. Warren, a pillar of neurogenetics (1953–2021)	127
Retraction Note: From neurons to microglia, with complements	125
Aversion crosses over	125
Marc G. Caron (1946–2022)	125
Glioblastoma–neuron networks	122
Negative self-experiences shape responses to others’ emotional states	119
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	119
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	117
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	116
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	116
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	116
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	115
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	115
Common and stimulus-type-specific brain representations of negative affect	113
A European perspective on structural barriers to women’s career progression in neuroscience	111
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	109
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	109
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	109
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	108
Activity map of a cortico-cerebellar loop underlying motor planning	103
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	102
A synergistic core for human brain evolution and cognition	102
Cerebellar organoids get active	101
Translation for transmission	101
Dopamine drives mating via cAMP	101
In conversation with Corey Harwell	100
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	97
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	97
Real control in virtual rats	97

Chronic brain recordings reveal objective biomarkers of chronic pain	96
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	95
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	95
Commensals boost nerve regeneration	95
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	91
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	90
Dynamics of mature myelin	90
Microglia contribute to the propagation of Aβ into unaffected brain tissue	90
Causal reductionism and causal structures	90
How to build a cognitive map	89
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	89
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	88
Big data for classifying ASD	88
A fragile imbalance	87
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	87
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	87
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	87
Personalized EES for SCI	84
In conversation with Carla Shatz	84
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	83
How the brain regulates its own immune system	82
Microglia set the pace for tau spread	82
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	82
Gene programs driving cortical neuron specifications	81
How collaboration between bioethicists and neuroscientists can advance research	81
From pain to brain	81
AI predicts risk of mental health disorders	81
Reply to: A curious concept of CNS clearance	80
Re-conceptualizing domains in neuroscience, hopes and utopias aside	80
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	79
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	78
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	78
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	78
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	78
Thalamus-driven functional populations in frontal cortex support decision-making	78
Shared computational principles for language processing in humans and deep language models	77
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	77
Natural language instructions induce compositional generalization in networks of neurons	76
Using temperature to analyze the neural basis of a time-based decision	76
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	75
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	75
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	74
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	74
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	74
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	73
Semantic reconstruction of continuous language from non-invasive brain recordings	73
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	73
In conversation with Fernando de Castro Soubriet	72
Complex topology meets simple statistics	72
(Lost) gut feeling	72
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	72
Restoring sensation to prosthetics	72
Gonads drive the brain	72
Author Correction: Disordered grids in the third dimension	70
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	70
Refining the negative into general and specific	70
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	69
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	69
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	69
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	68
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	67
Silencing gut CCK cells alters gut reaction to sugar	67
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	67
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	67
Spatially clustered neurons in the bat midbrain encode vocalization categories	66
Sleep cycles process memories	66
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	65
A. D. (Bud) Craig, Jr. (1951–2023)	65
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	65
Thalamic subnetworks as units of function	64
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	64
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	64
Neurogenic–angiogenic synchrony via lactate	64
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	64
Large-scale high-density brain-wide neural recording in nonhuman primates	63
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	62
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	62
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	61
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	61
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	61

Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	61
The cell-type underpinnings of the human functional cortical connectome	60
Anorexia nervosa microbiota	60
Salience in the raphe	60
Polygenic risk scores do not add value for predicting schizophrenia outcomes	60
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	59
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	59
The eyes have it	59
A very sexy circuit	59
A common voice for neural data	59
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	59
Adult neurogenesis is altered in neurodegenerative disease	57
High-precision mapping reveals the structure of odor coding in the human brain	57
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	57
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	57
AI beats neuroscientists’ predictions	57
Stress and autophagy	57
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	57
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	56
Resilient cortical maps	56
Serotonin and addiction prevention	56
Endocannabinoid protection of the brain vasculature leads to stress resilience	56
Updating the striatal–pallidal wiring diagram	55
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	55
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	55
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence	54
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
Cerebellar associative learning underlies skilled reach adaptation	54
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	54
The role of the lateral orbitofrontal cortex in creating cognitive maps	54
Cortical interneurons in autism	53
Magnetic resonance-based eye tracking using deep neural networks	53
Control and recalibration of path integration in place cells using optic flow	52
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	52
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	52
Blood-to-brain communication in aging and rejuvenation	52
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	52
Gradients of neurotransmitter receptor expression in the macaque cortex	52
Propagation of neuronal micronuclei regulates microglial characteristics	52
In conversation with Aniruddha Das	52
Place fields illuminated	51
Blood proteins control microglia	51
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	51
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	51
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	51
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	50
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	50
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	50
Puberty reverses sex differences in learning	50
Altruism and social rewards	50
A distinct hypothalamus–habenula circuit governs risk preference	49
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	49
Multilevel visual motion opponency in Drosophila	49
Lewy body disease can spread via two distinct body-first routes	49
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	48
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	48
Reducing publication bias with Registered Reports	48
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	47
Precisely timed theta oscillations are selectively required during the encoding phase of memory	47
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	46
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	45
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	45
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	45
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	45
Value dynamics affect choice preparation during decision-making	45
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	44
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	44
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	44
Twenty-five years of Nature Neuroscience	43
A unifying theory explains seemingly contradictory biases in perceptual estimation	43
The stop and go of glymphatic flow	43
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	43
Together but opposites in reward	43
A cholinergic auditory pathway	43
Lack of myelin improves axon survival in inflammatory lesions in the CNS	43
Adolescent sleep molds adult social preferences	43
Integrated cardio-behavioral responses to threat define defensive states	43
A motor association area in the depths of the central sulcus	42
Functionally diverse human insular architecture with memory-related hippocampal interactions	42
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	42
Orexin neurons track temporal features of blood glucose in behaving mice	42
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler	42
Prefrontal engrams of long-term fear memory perpetuate pain perception	42
Corticospinal populations broadcast complex motor signals to coordinated spinal and striatal circuits	41
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	41
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	41
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	41
Parallel gut-to-brain pathways orchestrate feeding behaviors	41
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage	41
Norepinephrine links astrocytic activity to regulation of cortical state	41
Single-neuron projectome of mouse prefrontal cortex	40
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	40
Humans can intermittently respond to verbal stimuli when sleeping	40
Impaired gut barrier affects microglia health	40