Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	498
Salty licorice taste receptor	481
Intracellular chloride regulation mediates local sleep pressure in the cortex	406
Non-REM sleep substates separate old and new memories	401
Alcohol’s necessary accessory	367
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	320
Computational complexity drives sustained deliberation	309
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	301
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	286
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	256
Differential replay of reward and punishment paths predicts approach and avoidance	241
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways	228
Implementation and validation of single-cell genomics experiments in neuroscience	220
Neural basis of anticipation and premature impulsive action in the frontal cortex	213
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	212
Daily feeding entrains hunger-sensing neurons	207
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	204
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	203
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	202
Climbing fibers provide essential instructive signals for associative learning	202
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	191
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	189
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	187
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	186
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	181

Pervasive environmental chemicals impair oligodendrocyte development	181
Genetic variants associated with longitudinal changes in brain structure across the lifespan	177
Neurons in the caudal ventrolateral medulla mediate descending pain control	171
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	170
Guest star in OCD	168
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	168
Computational strategies for deliberative thought	167
Organizing principles of the prefrontal cortex from a single-neuron projectome	166
COVID-19 and brain aging	162
How cancer and cortex collude	161
Lessons from resilience	157
Retraction Note: From neurons to microglia, with complements	150
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	147
Glioblastoma–neuron networks	145
Negative self-experiences shape responses to others’ emotional states	142
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	140
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	139
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	138
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	136
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	136
Marc G. Caron (1946–2022)	132
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	132
Aversion crosses over	132
Widespread brain–body integration during changes of arousal	131
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	130
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	126
A synergistic core for human brain evolution and cognition	124
The developmental emergence of reliable cortical representations	123
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	122
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	121
Common and stimulus-type-specific brain representations of negative affect	121
A neural mechanism for conserved value computations integrating information and rewards	121
Aging and injury drive neuronal senescence in the dorsal root ganglia	120
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	119
A European perspective on structural barriers to women’s career progression in neuroscience	118
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	117
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	116
Activity map of a cortico-cerebellar loop underlying motor planning	112
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	110
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	110
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	107
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	107
Translation for transmission	106
In conversation with Corey Harwell	106
Adult-born dentate granule cells promote hippocampal population sparsity	106
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	104
Cerebellar organoids get active	104
Real control in virtual rats	103
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	103
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	103

Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	99
Commensals boost nerve regeneration	99
Chronic brain recordings reveal objective biomarkers of chronic pain	98
Big data for classifying ASD	98
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	97
Facial expressions in mice reveal latent cognitive variables and their neural correlates	97
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	97
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	96
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	95
Dynamics of mature myelin	95
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	95
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	92
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	92
Microglia contribute to the propagation of Aβ into unaffected brain tissue	90
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	90
A fragile imbalance	89
How to build a cognitive map	89
Personalized EES for SCI	88
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	88
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	88
In conversation with Carla Shatz	87
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	87
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	86
AI predicts risk of mental health disorders	85
Re-conceptualizing domains in neuroscience, hopes and utopias aside	85
How collaboration between bioethicists and neuroscientists can advance research	85
Gene programs driving cortical neuron specifications	84
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	84
From pain to brain	84
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	83
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	82
How the brain regulates its own immune system	82
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	81
Using temperature to analyze the neural basis of a time-based decision	81
Thalamus-driven functional populations in frontal cortex support decision-making	81
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	80
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	79
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	79
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	79
Semantic reconstruction of continuous language from non-invasive brain recordings	78
Reply to: A curious concept of CNS clearance	78
Shared computational principles for language processing in humans and deep language models	78
Natural language instructions induce compositional generalization in networks of neurons	77
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	77
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	77
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	77
(Lost) gut feeling	76
Complex topology meets simple statistics	75
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	75
Gonads drive the brain	75
Refining the negative into general and specific	74
In conversation with Fernando de Castro Soubriet	74
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	74
Restoring sensation to prosthetics	74
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	73
Author Correction: Disordered grids in the third dimension	73
The cell-type underpinnings of the human functional cortical connectome	72
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	72
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	71
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	70
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	70
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	70
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	69
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	69
Neurogenic–angiogenic synchrony via lactate	69
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	69
A. D. (Bud) Craig, Jr. (1951–2023)	68
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	67
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	67
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	67
Sleep cycles process memories	67
Silencing gut CCK cells alters gut reaction to sugar	67
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	66
Spatially clustered neurons in the bat midbrain encode vocalization categories	66
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	66
Thalamic subnetworks as units of function	66
Large-scale high-density brain-wide neural recording in nonhuman primates	66
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	66
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	65
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	65

Anorexia nervosa microbiota	63
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	63
Salience in the raphe	63
A common voice for neural data	62
A very sexy circuit	62
The eyes have it	62
Polygenic risk scores do not add value for predicting schizophrenia outcomes	62
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	61
Cerebellar associative learning underlies skilled reach adaptation	61
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	61
Serotonin and addiction prevention	60
AI beats neuroscientists’ predictions	60
Resilient cortical maps	60
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	60
Endocannabinoid protection of the brain vasculature leads to stress resilience	60
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	60
The role of the lateral orbitofrontal cortex in creating cognitive maps	59
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	59
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence	59
Blood-to-brain communication in aging and rejuvenation	59
Adult neurogenesis is altered in neurodegenerative disease	59
Stress and autophagy	58
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	58
Gradients of neurotransmitter receptor expression in the macaque cortex	58
Magnetic resonance-based eye tracking using deep neural networks	58
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	58
Control and recalibration of path integration in place cells using optic flow	57
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	57
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	56
Propagation of neuronal micronuclei regulates microglial characteristics	56
High-precision mapping reveals the structure of odor coding in the human brain	56
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	55
Updating the striatal–pallidal wiring diagram	55
Cortical interneurons in autism	55
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	55
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	55
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	54
In conversation with Aniruddha Das	54
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	54
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	54
Blood proteins control microglia	54
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	53
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	53
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	53
Place fields illuminated	53
Lewy body disease can spread via two distinct body-first routes	52
Altruism and social rewards	52
Puberty reverses sex differences in learning	52
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	52
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	51
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	51
Value dynamics affect choice preparation during decision-making	51
A unifying theory explains seemingly contradictory biases in perceptual estimation	51
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	51
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	50
Reducing publication bias with Registered Reports	50
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	49
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	49
Multilevel visual motion opponency in Drosophila	49
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	49
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	49
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	49
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	48
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	48
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	48
A distinct hypothalamus–habenula circuit governs risk preference	48
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	47
Precisely timed theta oscillations are selectively required during the encoding phase of memory	47
Lack of myelin improves axon survival in inflammatory lesions in the CNS	47
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	46
Integrated cardio-behavioral responses to threat define defensive states	46
Twenty-five years of Nature Neuroscience	46
Together but opposites in reward	46
Adolescent sleep molds adult social preferences	46
A cholinergic auditory pathway	46
Functionally diverse human insular architecture with memory-related hippocampal interactions	45
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler	45
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	44
Impaired gut barrier affects microglia health	44
Parallel gut-to-brain pathways orchestrate feeding behaviors	44
Single-neuron projectome of mouse prefrontal cortex	44
A motor association area in the depths of the central sulcus	44
The stop and go of glymphatic flow	44
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	44
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	43
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	43
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	43
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage	43
Corticospinal populations broadcast complex motor signals to coordinated spinal and striatal circuits	43
Orexin neurons track temporal features of blood glucose in behaving mice	43
Prefrontal engrams of long-term fear memory perpetuate pain perception	43
Norepinephrine links astrocytic activity to regulation of cortical state	42
Humans can intermittently respond to verbal stimuli when sleeping	42