Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	419
Salty licorice taste receptor	410
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	409
Non-REM sleep substates separate old and new memories	364
Alcohol’s necessary accessory	341
Maybe too much of a good thing in gene therapy	325
Neural basis of anticipation and premature impulsive action in the frontal cortex	304
Computational complexity drives sustained deliberation	278
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	271
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	260
Neurons in the caudal ventrolateral medulla mediate descending pain control	260
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	255
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways	232
Implementation and validation of single-cell genomics experiments in neuroscience	225
Intracellular chloride regulation mediates local sleep pressure in the cortex	212
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	209
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	200
Differential replay of reward and punishment paths predicts approach and avoidance	182
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	181
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	179
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	179
Climbing fibers provide essential instructive signals for associative learning	178
Daily feeding entrains hunger-sensing neurons	176
Genetic variants associated with longitudinal changes in brain structure across the lifespan	175
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	168

Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	166
Revisiting the neurovascular unit	166
Pervasive environmental chemicals impair oligodendrocyte development	162
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	159
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	155
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	154
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	154
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics	152
Computational strategies for deliberative thought	151
Guest star in OCD	151
COVID-19 and brain aging	148
Organizing principles of the prefrontal cortex from a single-neuron projectome	147
How cancer and cortex collude	146
Lessons from resilience	144
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	143
Activity map of a cortico-cerebellar loop underlying motor planning	142
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	141
A role for the cortex in sleep–wake regulation	138
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	137
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging	137
Common and stimulus-type-specific brain representations of negative affect	134
A European perspective on structural barriers to women’s career progression in neuroscience	132
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	132
Remembering Stephen T. Warren, a pillar of neurogenetics (1953–2021)	128
Marc G. Caron (1946–2022)	126
Aversion crosses over	125
Retraction Note: From neurons to microglia, with complements	123
Glioblastoma–neuron networks	122
Negative self-experiences shape responses to others’ emotional states	120
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	119
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	117
A synergistic core for human brain evolution and cognition	114
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	114
The developmental emergence of reliable cortical representations	112
A neural mechanism for conserved value computations integrating information and rewards	110
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	110
Adult-born dentate granule cells promote hippocampal population sparsity	110
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	108
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	107
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	107
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway	105
Dopamine drives mating via cAMP	104
Translation for transmission	103
Cerebellar organoids get active	103
In conversation with Corey Harwell	103
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement	102
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	102
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	102
How to build a cognitive map	100
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders	99

Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	99
Real control in virtual rats	98
Chronic brain recordings reveal objective biomarkers of chronic pain	98
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	98
Commensals boost nerve regeneration	96
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	96
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	95
Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time	94
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	91
Causal reductionism and causal structures	91
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	90
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	89
Microglia contribute to the propagation of Aβ into unaffected brain tissue	89
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	89
Dynamics of mature myelin	89
A fragile imbalance	88
In conversation with Carla Shatz	87
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	87
Personalized EES for SCI	87
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	86
Microglia set the pace for tau spread	85
AI predicts risk of mental health disorders	85
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	84
How collaboration between bioethicists and neuroscientists can advance research	83
Gene programs driving cortical neuron specifications	83
Natural language instructions induce compositional generalization in networks of neurons	82
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	82
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	82
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	80
Reply to: A curious concept of CNS clearance	79
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	78
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	78
Using temperature to analyze the neural basis of a time-based decision	78
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	78
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	77
Re-conceptualizing domains in neuroscience, hopes and utopias aside	77
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	77
How the brain regulates its own immune system	76
From pain to brain	76
Shared computational principles for language processing in humans and deep language models	75
Semantic reconstruction of continuous language from non-invasive brain recordings	75
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	75
(Lost) gut feeling	75
Thalamus-driven functional populations in frontal cortex support decision-making	75
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	75
Complex topology meets simple statistics	74
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	73
Gonads drive the brain	73
Neurogenic–angiogenic synchrony via lactate	73
In conversation with Fernando de Castro Soubriet	72
Restoring sensation to prosthetics	71
Killing ageing neurons, one cell at a time	70
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	70
Author Correction: Disordered grids in the third dimension	69
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	69
Silencing gut CCK cells alters gut reaction to sugar	69
Refining the negative into general and specific	69
A. D. (Bud) Craig, Jr. (1951–2023)	68
Spatially clustered neurons in the bat midbrain encode vocalization categories	68
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	68
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	68
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	67
Divergent projections of the paraventricular nucleus of the thalamus mediate the selection of passive and active defensive behaviors	67
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	67
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	67
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	66
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	66
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	66
Thalamic subnetworks as units of function	66
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	66
The cell-type underpinnings of the human functional cortical connectome	65
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	65
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	65
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	64
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	64
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	63
Polygenic risk scores do not add value for predicting schizophrenia outcomes	63
Salience in the raphe	63
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	63
A very sexy circuit	62

Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	62
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	62
Anorexia nervosa microbiota	62
A common voice for neural data	61
The eyes have it	60
Propagation of neuronal micronuclei regulates microglial characteristics	59
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	59
AI beats neuroscientists’ predictions	59
Adult neurogenesis is altered in neurodegenerative disease	59
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	58
Endocannabinoid protection of the brain vasculature leads to stress resilience	58
Serotonin and addiction prevention	57
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	57
Cortical interneurons in autism	56
Updating the striatal–pallidal wiring diagram	56
The role of the lateral orbitofrontal cortex in creating cognitive maps	56
Magnetic resonance-based eye tracking using deep neural networks	56
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	56
Gradients of neurotransmitter receptor expression in the macaque cortex	56
Cerebellar associative learning underlies skilled reach adaptation	56
Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer’s disease	55
Blood-to-brain communication in aging and rejuvenation	55
Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility	55
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	55
High-precision mapping reveals the structure of odor coding in the human brain	54
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	54
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	54
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	54
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
Lewy body disease can spread via two distinct body-first routes	53
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence	53
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	53
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	53
In conversation with Aniruddha Das	53
Control and recalibration of path integration in place cells using optic flow	53
A unifying theory explains seemingly contradictory biases in perceptual estimation	52
Blood proteins control microglia	52
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	51
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	51
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	51
A distinct hypothalamus–habenula circuit governs risk preference	50
Puberty reverses sex differences in learning	50
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	50
Place fields illuminated	50
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	49
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	49
Altruism and social rewards	49
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	49
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	49
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	48
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	48
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	48
Reducing publication bias with Registered Reports	48
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	47
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	47
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	47
Precisely timed theta oscillations are selectively required during the encoding phase of memory	47
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	46
Twenty-five years of Nature Neuroscience	46
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	46
Lack of myelin improves axon survival in inflammatory lesions in the CNS	46
Exome sequencing in obsessive–compulsive disorder reveals a burden of rare damaging coding variants	46
Multilevel visual motion opponency in Drosophila	46
Value dynamics affect choice preparation during decision-making	46
A cholinergic auditory pathway	45
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	45
Adolescent sleep molds adult social preferences	45
The stop and go of glymphatic flow	45
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	45
Impaired gut barrier affects microglia health	45
Causal role for the primate superior colliculus in the computation of evidence for perceptual decisions	44
Prefrontal engrams of long-term fear memory perpetuate pain perception	44
Together but opposites in reward	44
A motor association area in the depths of the central sulcus	44
Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia	44
Parallel gut-to-brain pathways orchestrate feeding behaviors	44
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors	44
Orexin neurons track temporal features of blood glucose in behaving mice	43
Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation	43
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	42
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler	42
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage	42
Corticospinal populations broadcast complex motor signals to coordinated spinal and striatal circuits	42
Formalizing planning and information search in naturalistic decision-making	42
Integrated cardio-behavioral responses to threat define defensive states	41
Single-neuron projectome of mouse prefrontal cortex	41
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	41
Norepinephrine links astrocytic activity to regulation of cortical state	41
A potential target for noninvasive neuromodulation of PTSD symptoms derived from focal brain lesions in veterans	40
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction	40
Do all norepinephrine surges disrupt sleep?	40
Humans can intermittently respond to verbal stimuli when sleeping	40
Myelin lipid metabolism can provide energy for starved axons	40
Separating cognitive and motor processes in the behaving mouse	40
It’s go time	40