Nature Neuroscience

Article	Citations
Maladaptive myelination promotes seizure progression in generalized epilepsy	550
Salty licorice taste receptor	508
Non-REM sleep substates separate old and new memories	437
Alcohol’s necessary accessory	424
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)	410
Intracellular chloride regulation mediates local sleep pressure in the cortex	339
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape	335
Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties	329
Neural basis of anticipation and premature impulsive action in the frontal cortex	304
Daily feeding entrains hunger-sensing neurons	264
Differential replay of reward and punishment paths predicts approach and avoidance	263
Neural basis of concurrent deliberation toward a choice and confidence judgment	256
Hippocampus shapes entorhinal cortical output through a direct feedback circuit	234
The cholinergic basal forebrain provides a parallel channel for state-dependent sensory signaling to auditory cortex	230
Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus	229
Latent neural population dynamics underlying breathing, opioid-induced respiratory depression and gasping	221
Computational complexity drives sustained deliberation	219
Implementation and validation of single-cell genomics experiments in neuroscience	219
Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling	215
Climbing fibers provide essential instructive signals for associative learning	203
Neurons in the caudal ventrolateral medulla mediate descending pain control	200
A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease	200
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development	199
Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience	197
Pervasive environmental chemicals impair oligodendrocyte development	191

Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy	187
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks	183
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics	183
Genetic variants associated with longitudinal changes in brain structure across the lifespan	182
A global multicohort study to map subcortical brain development and cognition in infancy and early childhood	178
Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy	176
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease	173
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration	171
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex	157
Guest star in OCD	156
Computational strategies for deliberative thought	155
Organizing principles of the prefrontal cortex from a single-neuron projectome	151
COVID-19 and brain aging	150
How cancer and cortex collude	147
Lessons from resilience	147
Retraction Note: From neurons to microglia, with complements	143
Glioblastoma–neuron networks	141
Marc G. Caron (1946–2022)	140
Negative self-experiences shape responses to others’ emotional states	140
Aversion crosses over	139
Widespread brain–body integration during changes of arousal	137
A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila	134
A European perspective on structural barriers to women’s career progression in neuroscience	133
Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD	130
Astrocytes make room for microglia	129
Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses	129
Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis	126
Adult-born dentate granule cells promote hippocampal population sparsity	125
Voltage imaging reveals hippocampal inhibitory dynamics shaping pyramidal memory-encoding sequences	125
Activity map of a cortico-cerebellar loop underlying motor planning	125
Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization	124
The developmental emergence of reliable cortical representations	123
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy	117
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing	115
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice	114
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs	114
A neural mechanism for conserved value computations integrating information and rewards	114
TDP-43 loss induces cryptic polyadenylation in ALS/FTD	113
A synergistic core for human brain evolution and cognition	112
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease	111
Aging and injury drive neuronal senescence in the dorsal root ganglia	109
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes	107
Antipsychotic drug efficacy correlates with the modulation of D1 rather than D2 receptor-expressing striatal projection neurons	107
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy	105
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease	105
Common and stimulus-type-specific brain representations of negative affect	105
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology	104
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy	104
Gender and geographical disparity in editorial boards of journals in psychology and neuroscience	104
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease	102

In conversation with Corey Harwell	101
Translation for transmission	100
Cerebellar organoids get active	100
Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics	99
Real control in virtual rats	99
Augmenting AMPA receptor signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery	97
Flipping APOE to reverse Alzheimer’s disease traits	97
Author Correction: Tracking neural activity from the same cells during the entire adult life of mice	97
Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time	97
Big data for classifying ASD	96
Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms	96
Commensals boost nerve regeneration	95
Chronic brain recordings reveal objective biomarkers of chronic pain	95
Facial expressions in mice reveal latent cognitive variables and their neural correlates	94
Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit	94
Trans-Seq maps a selective mammalian retinotectal synapse instructed by Nephronectin	94
A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging	94
Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury	93
Dynamics of mature myelin	93
Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys	93
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state	92
Increased neural excitability and glioma synaptic activity drives glioma proliferation in human cortex	91
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	88
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety	87
Impaired capillary–venous drainage contributes to gliosis and demyelination in mouse white matter during aging	87
Next steps for global collaboration to minimize racial and ethnic bias in neuroscience	85
A fragile imbalance	85
In conversation with Carla Shatz	85
How to build a cognitive map	85
Personalized EES for SCI	85
AI predicts risk of mental health disorders	84
Publisher Correction: Nested compressed co-representations of multiple sequential experiences during sleep	84
Gene programs driving cortical neuron specifications	82
Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells	82
From pain to brain	81
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis	81
How the brain regulates its own immune system	81
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement	80
Reply to: A curious concept of CNS clearance	80
How collaboration between bioethicists and neuroscientists can advance research	80
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways	79
Publisher Correction: Hormonal milieu influences whole-brain structural dynamics across the menstrual cycle using dense sampling in multiple individuals	78
Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health	78
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis	78
Using temperature to analyze the neural basis of a time-based decision	78
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression	77
Thalamus-driven functional populations in frontal cortex support decision-making	77
Shared computational principles for language processing in humans and deep language models	77
Intermediate acoustic-to-semantic representations link behavioral and neural responses to natural sounds	77
Single-cell genotyping and transcriptomic profiling of mosaic focal cortical dysplasia	76
Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model	76
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve	75
Semantic reconstruction of continuous language from non-invasive brain recordings	75
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	75
Natural language instructions induce compositional generalization in networks of neurons	75
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis	75
Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice	74
Complex topology meets simple statistics	74
Gonads drive the brain	74
(Lost) gut feeling	74
Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques	73
In conversation with Fernando de Castro Soubriet	73
Noninvasive reduction of neural rigidity alters autistic behaviors in humans	73
Refining the negative into general and specific	73
Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses	72
Neurogenic–angiogenic synchrony via lactate	71
Sleep cycles process memories	71
Silencing gut CCK cells alters gut reaction to sugar	71
Large-scale high-density brain-wide neural recording in nonhuman primates	70
TDP-43 loss brings RNA to a twist ending	70
A. D. (Bud) Craig, Jr. (1951–2023)	70
Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration	69
Spatially clustered neurons in the bat midbrain encode vocalization categories	69
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus	69
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice	68
Restoring sensation to prosthetics	67
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus	67
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains	66
Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy	66
Estrogen dominance drives distinct patterns of brain plasticity	66

The cell-type underpinnings of the human functional cortical connectome	65
Semi-orthogonal subspaces for value mediate a binding and generalization trade-off	65
Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice	65
Central nervous system-associated macrophages modulate the immune response following stroke in aged mice	65
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error	64
Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood	64
A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety	64
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation	64
Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)	64
Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy	63
Anorexia nervosa microbiota	63
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	63
Salience in the raphe	63
Thalamic subnetworks as units of function	63
Author Correction: Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons	62
The eyes have it	62
Glial plasticity dysregulation contributes to learning impairments in the neurogenetic disorder NF1	62
A common voice for neural data	62
Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans	62
A very sexy circuit	62
Endocannabinoid protection of the brain vasculature leads to stress resilience	61
AI beats neuroscientists’ predictions	61
Resilient cortical maps	61
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance	60
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking	59
Stress and autophagy	59
Author Correction: Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain	59
Propagation of neuronal micronuclei regulates microglial characteristics	59
Author Correction: Meta-reinforcement learning via orbitofrontal cortex	59
High-precision mapping reveals the structure of odor coding in the human brain	58
Cerebellar associative learning underlies skilled reach adaptation	58
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex	57
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons	57
Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation	56
Blood-to-brain communication in aging and rejuvenation	56
Updating the striatal–pallidal wiring diagram	56
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition	56
Decoding motor plans using a closed-loop ultrasonic brain–machine interface	56
Control and recalibration of path integration in place cells using optic flow	56
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	54
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning	54
Gradients of neurotransmitter receptor expression in the macaque cortex	54
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time	54
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior	53
Blood proteins control microglia	53
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia	53
The role of the lateral orbitofrontal cortex in creating cognitive maps	53
Neuronal activity stimulates a genetic program to rapidly generate synapses during development	52
Place fields illuminated	52
In conversation with Aniruddha Das	52
Author Correction: Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance	52
Author Correction: Large-scale encoding of emotion concepts becomes increasingly similar between individuals from childhood to adolescence	52
Puberty reverses sex differences in learning	51
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment	51
Altruism and social rewards	51
Lewy body disease can spread via two distinct body-first routes	51
Value dynamics affect choice preparation during decision-making	50
Reducing publication bias with Registered Reports	50
Multilevel visual motion opponency in Drosophila	50
A distinct hypothalamus–habenula circuit governs risk preference	50
CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes	50
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery	50
Apolipoprotein E in Alzheimer’s disease trajectories and the next-generation clinical care pathway	50
Serotonergic modulation of the BNST–CeA pathway reveals sex differences in fear learning	50
Context-dependent decision-making in the primate hippocampal–prefrontal circuit	49
Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution	49
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution	49
High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations	48
Distinct origin and region-dependent contribution of stromal fibroblasts to fibrosis following traumatic injury in mice	48
Membrane mechanics dictate axonal pearls-on-a-string morphology and function	48
A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning	47
A unifying theory explains seemingly contradictory biases in perceptual estimation	47
Adolescent sleep molds adult social preferences	46
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification	46
Lack of myelin improves axon survival in inflammatory lesions in the CNS	46
Neural patterns differentiate traumatic from sad autobiographical memories in PTSD	46
A cholinergic auditory pathway	46
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	46
Author Correction: A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function	45
Integrated cardio-behavioral responses to threat define defensive states	45
Twenty-five years of Nature Neuroscience	45
The stop and go of glymphatic flow	45
Functionally diverse human insular architecture with memory-related hippocampal interactions	45
Together but opposites in reward	45
An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates	45
Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits	44
Impaired gut barrier affects microglia health	44
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	43
A motor association area in the depths of the central sulcus	43
Orexin neurons track temporal features of blood glucose in behaving mice	43
Prefrontal engrams of long-term fear memory perpetuate pain perception	43
Single-neuron projectome of mouse prefrontal cortex	43
In conversation with Sonia Mayoral	42
It’s go time	42
Norepinephrine links astrocytic activity to regulation of cortical state	42