Nature Neuroscience

Papers
(The median citation count of Nature Neuroscience is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Reactive astrocyte nomenclature, definitions, and future directions1053
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19872
Parameterizing neural power spectra into periodic and aperiodic components809
Synergy between amyloid-β and tau in Alzheimer’s disease559
Disease-associated astrocytes in Alzheimer’s disease and aging500
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex400
Using Bayes factor hypothesis testing in neuroscience to establish evidence of absence346
The extent and drivers of gender imbalance in neuroscience reference lists299
Topographic organization of the human subcortex unveiled with functional connectivity gradients288
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization281
Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map281
The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice277
Neuroinflammatory astrocyte subtypes in the mouse brain267
Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons256
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques245
Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia238
Considering sex as a biological variable will require a global shift in science culture235
Revisiting the neurovascular unit232
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease225
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits222
An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank204
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions200
Motor learning promotes remyelination via new and surviving oligodendrocytes198
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level194
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles189
Long-term maturation of human cortical organoids matches key early postnatal transitions181
Machine translation of cortical activity to text with an encoder–decoder framework179
Brain capillary pericytes exert a substantial but slow influence on blood flow177
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys176
Microglia phagocytose myelin sheaths to modify developmental myelination170
A community-based transcriptomics classification and nomenclature of neocortical cell types170
Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo165
Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning159
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells157
AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset157
Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice157
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain157
Edge-centric functional network representations of human cerebral cortex reveal overlapping system-level architecture157
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis154
Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons153
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease149
Interplay between persistent activity and activity-silent dynamics in the prefrontal cortex underlies serial biases in working memory148
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production148
Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72147
Quantifying behavior to understand the brain147
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing142
Revealing the structure of pharmacobehavioral space through motion sequencing138
Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury138
A genetically encoded sensor for measuring serotonin dynamics134
Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia134
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis133
Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits132
Neural mechanisms of aggression across species129
Large-scale neural recordings call for new insights to link brain and behavior127
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction127
Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans126
Acute social isolation evokes midbrain craving responses similar to hunger126
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence121
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex121
Active dendritic currents gate descending cortical outputs in perception119
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease114
CNS fibroblasts form a fibrotic scar in response to immune cell infiltration113
Recent advances in neurotechnologies with broad potential for neuroscience research112
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer’s disease112
The claustrum coordinates cortical slow-wave activity111
Shared computational principles for language processing in humans and deep language models110
High-fat food biases hypothalamic and mesolimbic expression of consummatory drives109
Diversity and dynamism in the cerebellum108
Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits107
Issues and recommendations from the OHBM COBIDAS MEEG committee for reproducible EEG and MEG research107
Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD106
Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex106
Identification of neural oscillations and epileptiform changes in human brain organoids105
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics105
Recurrent architecture for adaptive regulation of learning in the insect brain104
Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons104
Transcriptomic organization of the human brain in post-traumatic stress disorder103
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges100
Prefrontal–amygdala circuits in social decision-making99
Anatomically segregated basal ganglia pathways allow parallel behavioral modulation97
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders96
Spatial and cell type transcriptional landscape of human cerebellar development96
Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels93
Challenges and future directions for representations of functional brain organization93
Wireless multilateral devices for optogenetic studies of individual and social behaviors93
A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice93
Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit93
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice93
Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression92
Brainstem neurons that command mammalian locomotor asymmetries91
A prefrontal–paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice91
Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer’s disease90
Dense neuronal reconstruction through X-ray holographic nano-tomography90
Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks88
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble88
Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition88
Live-imaging of astrocyte morphogenesis and function in zebrafish neural circuits87
General anesthetics activate a potent central pain-suppression circuit in the amygdala87
Microglia contribute to the propagation of Aβ into unaffected brain tissue86
Rotational dynamics reduce interference between sensory and memory representations86
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine85
The neural basis of psychedelic action84
Circuit and molecular architecture of a ventral hippocampal network84
A glycolytic shift in Schwann cells supports injured axons84
Decoding molecular and cellular heterogeneity of mouse nucleus accumbens84
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine84
GABAergic signaling to astrocytes in the prefrontal cortex sustains goal-directed behaviors83
Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents83
Single-neuron projectome of mouse prefrontal cortex83
Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia83
Prefrontal cortex exhibits multidimensional dynamic encoding during decision-making82
Microglial Gi-dependent dynamics regulate brain network hyperexcitability82
Long-term self-renewing stem cells in the adult mouse hippocampus identified by intravital imaging81
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB81
Brain proteome-wide association study implicates novel proteins in depression pathogenesis81
Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain80
Synaptic vesicles transiently dock to refill release sites80
An amygdala-to-hypothalamus circuit for social reward80
Mice alternate between discrete strategies during perceptual decision-making80
A shared disease-associated oligodendrocyte signature among multiple CNS pathologies79
Gene-based therapies for neurodegenerative diseases79
Attractor dynamics gate cortical information flow during decision-making78
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies77
Hippocampal neurons represent events as transferable units of experience77
Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity77
A synergistic core for human brain evolution and cognition76
Probing neural codes with two-photon holographic optogenetics75
An investigation across 45 languages and 12 language families reveals a universal language network75
RNA transport and local translation in neurodevelopmental and neurodegenerative disease75
Cortical-like dynamics in recurrent circuits optimized for sampling-based probabilistic inference74
Maternal immune activation in mice disrupts proteostasis in the fetal brain73
The role of population structure in computations through neural dynamics73
Modeling behaviorally relevant neural dynamics enabled by preferential subspace identification72
Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders72
Within-group synchronization in the prefrontal cortex associates with intergroup conflict71
Assessing the depth of language processing in patients with disorders of consciousness70
How to establish robust brain–behavior relationships without thousands of individuals70
Tau induces PSD95–neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration70
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity70
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states70
Genetic variants associated with longitudinal changes in brain structure across the lifespan69
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration68
The preference for sugar over sweetener depends on a gut sensor cell68
The basal ganglia control the detailed kinematics of learned motor skills68
Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology67
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines67
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis67
Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival66
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing66
A role for the cortex in sleep–wake regulation66
Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk66
Cortical interneurons in autism64
Medial preoptic area antagonistically mediates stress-induced anxiety and parental behavior64
Visual and linguistic semantic representations are aligned at the border of human visual cortex64
Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice64
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines63
The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development63
Multiple convergent hypothalamus–brainstem circuits drive defensive behavior62
Inferences on a multidimensional social hierarchy use a grid-like code62
Conservation of brain connectivity and wiring across the mammalian class62
CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation61
Periods of synchronized myelin changes shape brain function and plasticity61
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons61
Four core properties of the human brain valuation system demonstrated in intracranial signals60
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting60
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error59
Complementary contributions of non-REM and REM sleep to visual learning58
Distinct synchronization, cortical coupling and behavioral function of two basal forebrain cholinergic neuron types58
Posterior amygdala regulates sexual and aggressive behaviors in male mice58
Temporally distinct myeloid cell responses mediate damage and repair after cerebrovascular injury58
Semantic reconstruction of continuous language from non-invasive brain recordings58
Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model57
Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior57
Independent generation of sequence elements by motor cortex57
Targeted photostimulation uncovers circuit motifs supporting short-term memory56
Association between real-world experiential diversity and positive affect relates to hippocampal–striatal functional connectivity56
Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression-like states56
Neural fragility as an EEG marker of the seizure onset zone56
Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation55
Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition54
Membrane potential dynamics underlying context-dependent sensory responses in the hippocampus54
Associative and plastic thalamic signaling to the lateral amygdala controls fear behavior54
Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function54
Genetically identified amygdala–striatal circuits for valence-specific behaviors54
Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis54
Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotective54
A quantitative reward prediction error signal in the ventral pallidum54
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways53
Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior53
Identification of early neurodegenerative pathways in progressive multiple sclerosis53
Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections52
Primate auditory prototype in the evolution of the arcuate fasciculus52
Pain modulates dopamine neurons via a spinal–parabrachial–mesencephalic circuit51
How to build a cognitive map51
Sustained effects of rapidly acting antidepressants require BDNF-dependent MeCP2 phosphorylation51
A parsimonious description of global functional brain organization in three spatiotemporal patterns51
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging51
AHR is a Zika virus host factor and a candidate target for antiviral therapy51
Correlations enhance the behavioral readout of neural population activity in association cortex51
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway51
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life50
USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans50
New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination50
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging50
A cortical circuit for audio-visual predictions50
Systematic errors in connectivity inferred from activity in strongly recurrent networks49
Neurons detect cognitive boundaries to structure episodic memories in humans49
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation49
Mesophasic organization of GABAA receptors in hippocampal inhibitory synapses49
Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement49
Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice48
Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia48
Interneuron origin and molecular diversity in the human fetal brain48
Causal role for the primate superior colliculus in the computation of evidence for perceptual decisions48
Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor48
Episodic memory retrieval success is associated with rapid replay of episode content48
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration47
Cross-hemispheric gamma synchrony between prefrontal parvalbumin interneurons supports behavioral adaptation during rule shift learning47
Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics47
Synaptic plasticity as Bayesian inference47
Placental endocrine function shapes cerebellar development and social behavior47
Dynamic representations in networked neural systems47
Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation46
Sleep down state-active ID2/Nkx2.1 interneurons in the neocortex46
Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations45
Thalamic subnetworks as units of function45
Deconstructing the neurobiology of cannabis use disorder45
Baseline brain function in the preadolescents of the ABCD Study45
Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer’s disease model mice44
Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia43
Reactivation predicts the consolidation of unbiased long-term cognitive maps43
Cerebellar granule cell axons support high-dimensional representations43
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus42
Multimodal neural recordings with Neuro-FITM uncover diverse patterns of cortical–hippocampal interactions42
Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system42
Adaptive circuit dynamics across human cortex during evidence accumulation in changing environments42
Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits41
An emergent neural coactivity code for dynamic memory41
Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility41
Memory trace interference impairs recall in a mouse model of Alzheimer’s disease40
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells40
A thalamo-amygdalar circuit underlying the extinction of remote fear memories40
Experience-dependent contextual codes in the hippocampus40
Emerging phenotyping strategies will advance our understanding of psychiatric genetics39
Massively parallel techniques for cataloguing the regulome of the human brain39
Vector trace cells in the subiculum of the hippocampal formation39
Formalizing planning and information search in naturalistic decision-making39
Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB38
Confronting racially exclusionary practices in the acquisition and analyses of neuroimaging data37
Anatomic resolution of neurotransmitter-specific projections to the VTA reveals diversity of GABAergic inputs37
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