OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Neuroscience is 94. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Reactive astrocyte nomenclature, definitions, and future directions	1374
Parameterizing neural power spectra into periodic and aperiodic components	1163
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19	984
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex	598
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization	394
Neuroinflammatory astrocyte subtypes in the mouse brain	359
Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques	359
Revisiting the neurovascular unit	327
The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice	311
An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank	311
Considering sex as a biological variable will require a global shift in science culture	293
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level	290
Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia	289
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease	284
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex	266
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions	260
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease	251
Long-term maturation of human cortical organoids matches key early postnatal transitions	237
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis	228
Brain capillary pericytes exert a substantial but slow influence on blood flow	227
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain	226
AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset	219
Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo	219
A massive 7T fMRI dataset to bridge cognitive neuroscience and artificial intelligence	216
Quantifying behavior to understand the brain	203

Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice	202
Shared computational principles for language processing in humans and deep language models	200
Large-scale neural recordings call for new insights to link brain and behavior	190
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production	188
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells	178
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction	176
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing	174
A genetically encoded sensor for measuring serotonin dynamics	173
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB	164
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis	164
Acute social isolation evokes midbrain craving responses similar to hunger	162
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration	151
Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex	148
Identification of neural oscillations and epileptiform changes in human brain organoids	147
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease	147
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer’s disease	144
Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits	143
CNS fibroblasts form a fibrotic scar in response to immune cell infiltration	143
Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons	137
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders	137
The neural basis of psychedelic action	136
Recent advances in neurotechnologies with broad potential for neuroscience research	135
Prefrontal–amygdala circuits in social decision-making	133
Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders	133
An investigation across 45 languages and 12 language families reveals a universal language network	133
Diversity and dynamism in the cerebellum	132
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics	131
Mice alternate between discrete strategies during perceptual decision-making	128
Spatial and cell type transcriptional landscape of human cerebellar development	128
Decoding molecular and cellular heterogeneity of mouse nucleus accumbens	126
Rotational dynamics reduce interference between sensory and memory representations	125
Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit	124
A synergistic core for human brain evolution and cognition	124
Transcriptomic organization of the human brain in post-traumatic stress disorder	123
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity	123
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine	122
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine	120
Semantic reconstruction of continuous language from non-invasive brain recordings	119
Single-neuron projectome of mouse prefrontal cortex	119
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges	119
Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels	118
Wireless multilateral devices for optogenetic studies of individual and social behaviors	117
Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia	117
A shared disease-associated oligodendrocyte signature among multiple CNS pathologies	113
Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition	112
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies	110
Brain proteome-wide association study implicates novel proteins in depression pathogenesis	109
How to establish robust brain–behavior relationships without thousands of individuals	109
The basal ganglia control the detailed kinematics of learned motor skills	108
Microglia contribute to the propagation of Aβ into unaffected brain tissue	107

Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer’s disease	107
Gene-based therapies for neurodegenerative diseases	107
Genetic variants associated with longitudinal changes in brain structure across the lifespan	106
Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents	104
GABAergic signaling to astrocytes in the prefrontal cortex sustains goal-directed behaviors	104
An amygdala-to-hypothalamus circuit for social reward	104
Inferences on a multidimensional social hierarchy use a grid-like code	103
How to build a cognitive map	101
Maternal immune activation in mice disrupts proteostasis in the fetal brain	100
RNA transport and local translation in neurodevelopmental and neurodegenerative disease	100
Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology	100
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis	100
The role of population structure in computations through neural dynamics	100
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states	98
Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks	98
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience	96
Probing neural codes with two-photon holographic optogenetics	95
The preference for sugar over sweetener depends on a gut sensor cell	94
Microglial Gi-dependent dynamics regulate brain network hyperexcitability	94
Long-term self-renewing stem cells in the adult mouse hippocampus identified by intravital imaging	94