Metabolic Engineering

Article	Citations
Towards bio-upcycling of polyethylene terephthalate	151
CRISPR/Cas9 directed editing of lycopene epsilon-cyclase modulates metabolic flux for β-carotene biosynthesis in banana fruit	143
Machine learning for metabolic engineering: A review	135
Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator	94
Dynamic control in metabolic engineering: Theories, tools, and applications	91
In vitro prototyping of limonene biosynthesis using cell-free protein synthesis	79
Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440	77
Engineering the oleaginous yeast Yarrowia lipolytica for high-level resveratrol production	75
Tandem chemical deconstruction and biological upcycling of poly(ethylene terephthalate) to β-ketoadipic acid by Pseudomonas putida KT2440	75
Enhancing isoprenoid synthesis in Yarrowia lipolytica by expressing the isopentenol utilization pathway and modulating intracellular hydrophobicity	75
Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeast	71
Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield	69
A guide to metabolic flux analysis in metabolic engineering: Methods, tools and applications	66
Engineered Pseudomonas putida simultaneously catabolizes five major components of corn stover lignocellulose: Glucose, xylose, arabinose, p-coumaric acid, and acetic acid	65
Targeting pathway expression to subcellular organelles improves astaxanthin synthesis in Yarrowia lipolytica	64
An optimized methanol assimilation pathway relying on promiscuous formaldehyde-condensing aldolases in E. coli	62
Development of a growth coupled and multi-layered dynamic regulation network balancing malonyl-CoA node to enhance (2S)-naringenin biosynthesis in Escherichia coli	62
Metabolic engineering of Saccharomyces cerevisiae for the de novo production of psilocybin and related tryptamine derivatives	61
Valorization of CO2 through lithoautotrophic production of sustainable chemicals in Cupriavidus necator	59
Stress-driven dynamic regulation of multiple tolerance genes improves robustness and productive capacity of Saccharomyces cerevisiae in industrial lignocellulose fermentation	58
Engineering yeast subcellular compartments for increased production of the lipophilic natural products ginsenosides	57
Combining genetically-encoded biosensors with high throughput strain screening to maximize erythritol production in Yarrowia lipolytica	57
Elucidation of the complete biosynthetic pathway of the main triterpene glycosylation products of Panax notoginseng using a synthetic biology platform	56
Total in vitro biosynthesis of the nonribosomal macrolactone peptide valinomycin	56
The metabolic potential of plastics as biotechnological carbon sources – Review and targets for the future	55

A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acids	53
Direct production of commodity chemicals from lignocellulose using Myceliophthora thermophila	53
High-yield production of L-valine in engineered Escherichia coli by a novel two-stage fermentation	51
Metabolic compartmentalization in yeast mitochondria: Burden and solution for squalene overproduction	51
Enzyme capacity-based genome scale modelling of CHO cells	51
Engineering Saccharomyces cerevisiae for high yield production of α-amyrin via synergistic remodeling of α-amyrin synthase and expanding the storage pool	49
Rebalancing microbial carbon distribution for L-threonine maximization using a thermal switch system	48
What CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines	48
Metabolic design for selective production of nicotinamide mononucleotide from glucose and nicotinamide	47
Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers	47
Metabolism of syringyl lignin-derived compounds in Pseudomonas putida enables convergent production of 2-pyrone-4,6-dicarboxylic acid	47
Efficient production of saffron crocins and picrocrocin in Nicotiana benthamiana using a virus-driven system	46
Green production of silybin and isosilybin by merging metabolic engineering approaches and enzymatic catalysis	46
Biosynthesis of functional polyhydroxyalkanoates by engineered Halomonas bluephagenesis	45
Revealing metabolic mechanisms of interaction in the anaerobic digestion microbiome by flux balance analysis	45
Direct biosynthesis of adipic acid from lignin-derived aromatics using engineered Pseudomonas putida KT2440	44
Synergistic improvement of N-acetylglucosamine production by engineering transcription factors and balancing redox cofactors	43
Simultaneous secretion of seven lignocellulolytic enzymes by an industrial second-generation yeast strain enables efficient ethanol production from multiple polymeric substrates	42
Systems metabolic engineering of Vibrio natriegens for the production of 1,3-propanediol	42
Tailoring cyanobacteria as a new platform for highly efficient synthesis of astaxanthin	42
Engineering Escherichia coli for production of geraniol by systematic synthetic biology approaches and laboratory-evolved fusion tags	42
Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy	41
Model-guided dynamic control of essential metabolic nodes boosts acetyl-coenzyme A–dependent bioproduction in rewired Pseudomonas putida	41
Cell-free styrene biosynthesis at high titers	41
Metabolic engineering of Cupriavidus necator H16 for improved chemoautotrophic growth and PHB production under oxygen-limiting conditions	40
Tailored biosynthesis of gibberellin plant hormones in yeast	39
Engineering carotenoid production in mammalian cells for nutritionally enhanced cell-cultured foods	39
Production of moth sex pheromones for pest control by yeast fermentation	38
Automated engineering of synthetic metabolic pathways for efficient biomanufacturing	38
Engineering of the 2,3-butanediol pathway of Paenibacillus polymyxa DSM 365	37
Engineering Cupriavidus necator H16 for the autotrophic production of (R)-1,3-butanediol	37
Guiding stars to the field of dreams: Metabolically engineered pathways and microbial platforms for a sustainable lignin-based industry	37
Engineering of Corynebacterium glutamicum for high-level γ-aminobutyric acid production from glycerol by dynamic metabolic control	37
High-throughput insertional mutagenesis reveals novel targets for enhancing lipid accumulation in Nannochloropsis oceanica	37
Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1	36
Metabolic engineering of type II methanotroph, Methylosinus trichosporium OB3b, for production of 3-hydroxypropionic acid from methane via a malonyl-CoA reductase-dependent pathway	36
Systematic identification and elimination of flux bottlenecks in the aldehyde production pathway of Synechococcus elongatus PCC 7942	35
Engineering Saccharomyces cerevisiae for isoprenol production	35
High efficient production of plant flavonoids by microbial cell factories: Challenges and opportunities	35
Enhancement of the flavone contents of Scutellaria baicalensis hairy roots via metabolic engineering using maize Lc and Arabidopsis PAP1 transcription factors	35
Comprehensive study on Escherichia coli genomic expression: Does position really matter?	34
Integrated knowledge mining, genome-scale modeling, and machine learning for predicting Yarrowia lipolytica bioproduction	34
Efficient production of oxidized terpenoids via engineering fusion proteins of terpene synthase and cytochrome P450	34
Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly	34
Development of Klebsiella pneumoniae J2B as microbial cell factory for the production of 1,3-propanediol from glucose	34
High-level sustainable production of the characteristic protopanaxatriol-type saponins from Panax species in engineered Saccharomyces cerevisiae	34
K-FIT: An accelerated kinetic parameterization algorithm using steady-state fluxomic data	34
Quorum sensing-mediated protein degradation for dynamic metabolic pathway control in Saccharomyces cerevisiae	33
Highly efficient production of L-homoserine in Escherichia coli by engineering a redox balance route	33
Independent component analysis of E. coli's transcriptome reveals the cellular processes that respond to heterologous gene expression	33

Rewiring carbon flux in Escherichia coli using a bifunctional molecular switch	33
In vivo evolutionary engineering of riboswitch with high-threshold for N-acetylneuraminic acid production	33
INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis	32
Engineering Escherichia coli for methanol-dependent growth on glucose for metabolite production	32
A hybrid mechanistic-empirical model for in silico mammalian cell bioprocess simulation	32
Improving CRISPR/Cas9-mediated genome editing efficiency in Yarrowia lipolytica using direct tRNA-sgRNA fusions	32
Structure-guided reshaping of the acyl binding pocket of ‘TesA thioesterase enhances octanoic acid production in E. coli	31
Unlocking the biosynthesis of sesquiterpenoids from methane via the methylerythritol phosphate pathway in methanotrophic bacteria, using α-humulene as a model compound	31
A genetic toolbox for metabolic engineering of Issatchenkia orientalis	31
Engineering Halomonas bluephagenesis for L-Threonine production	31
Animal-free heme production for artificial meat in Corynebacterium glutamicum via systems metabolic and membrane engineering	31
Constructing an ethanol utilization pathway in Escherichia coli to produce acetyl-CoA derived compounds	30
Cascaded valorization of brown seaweed to produce l-lysine and value-added products using Corynebacterium glutamicum streamlined by systems metabolic engineering	30
Promiscuous phosphoketolase and metabolic rewiring enables novel non-oxidative glycolysis in yeast for high-yield production of acetyl-CoA derived products	30
Portable bacterial CRISPR transcriptional activation enables metabolic engineering in Pseudomonas putida	30
Enhanced 2′-Fucosyllactose production by engineered Saccharomyces cerevisiae using xylose as a co-substrate	30
Heterologous production of the epoxycarotenoid violaxanthin in Saccharomyces cerevisiae	30
Overexpression of native ORANGE (OR) and OR mutant protein in Chlamydomonas reinhardtii enhances carotenoid and ABA accumulation and increases resistance to abiotic stress	29
Metabolic engineering for valorization of macroalgae biomass	29
Engineering cyanobacteria as cell factories for direct trehalose production from CO2	28
Engineering adipic acid metabolism in Pseudomonas putida	28
Engineering the permeability of Halomonas bluephagenesis enhanced its chassis properties	28
Metabolic flux analysis of the non-transitory starch tradeoff for lipid production in mature tobacco leaves	28
Machine-learning from Pseudomonas putida KT2440 transcriptomes reveals its transcriptional regulatory network	28
Characterization of aromatic acid/proton symporters in Pseudomonas putida KT2440 toward efficient microbial conversion of lignin-related aromatics	27
A modular autoinduction device for control of gene expression in Bacillus subtilis	27
Engineering Pseudomonas putida for efficient aromatic conversion to bioproduct using high throughput screening in a bioreactor	27
Organic waste conversion through anaerobic digestion: A critical insight into the metabolic pathways and microbial interactions	27
Biobased PET from lignin using an engineered cis, cis-muconate-producing Pseudomonas putida strain with superior robustness, energy and redox properties	27
Development of a clostridia-based cell-free system for prototyping genetic parts and metabolic pathways	27
Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster	27
The yeast platform engineered for synthetic gRNA-landing pads enables multiple gene integrations by a single gRNA/Cas9 system	27
Transportome-wide engineering of Saccharomyces cerevisiae	27
Isobutanol production in Corynebacterium glutamicum: Suppressed succinate by-production by pckA inactivation and enhanced productivity via the Entner–Doudoroff pathway	27
Rational engineering strategies for achieving high-yield, high-quality and high-stability of natural product production in actinomycetes	26
Metabolic engineering of E. coli for pyocyanin production	26
Systems metabolic engineering of Corynebacterium glutamicum for high-level production of 1,3-propanediol from glucose and xylose	26
Heterologous biosynthesis of lutein in S. cerevisiae enabled by temporospatial pathway control	26
Secretory production of spider silk proteins in metabolically engineered Corynebacterium glutamicum for spinning into tough fibers	26
Control of IgG glycosylation in CHO cell perfusion cultures by GReBA mathematical model supported by a novel targeted feed, TAFE	26
Engineering promiscuity of chloramphenicol acetyltransferase for microbial designer ester biosynthesis	26
Development of bifunctional biosensors for sensing and dynamic control of glycolysis flux in metabolic engineering	26
Recent advances in constraint and machine learning-based metabolic modeling by leveraging stoichiometric balances, thermodynamic feasibility and kinetic law formalisms	26
Metabolic engineering of Escherichia coli W3110 for efficient production of homoserine from glucose	25
Adaptive laboratory evolution of Escherichia coli lacking cellular byproduct formation for enhanced acetate utilization through compensatory ATP consumption	25
Debottlenecking 4-hydroxybenzoate hydroxylation in Pseudomonas putida KT2440 improves muconate productivity from p-coumarate	25
Pathway discovery and engineering for cleavage of a β-1 lignin-derived biaryl compound	25
Hydrogen utilization by Methylocystis sp. strain SC2 expands the known metabolic versatility of type IIa methanotrophs	25
Regulated redirection of central carbon flux enhances anaerobic production of bioproducts in Zymomonas mobilis	25
Engineering a powerful green cell factory for robust photoautotrophic diterpenoid production	25
Systematic identification of Ocimum sanctum sesquiterpenoid synthases and (−)-eremophilene overproduction in engineered yeast	25
Dynamic control over feedback regulatory mechanisms improves NADPH flux and xylitol biosynthesis in engineered E. coli	25
Engineering Halomonas bluephagenesis as a chassis for bioproduction from starch	25
Rewiring the native methanol assimilation metabolism by incorporating the heterologous ribulose monophosphate cycle into Methylorubrum extorquens	24
Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver	24
Integrating thermodynamic and enzymatic constraints into genome-scale metabolic models	24
Single-gene regulated non-spore-forming Bacillus subtilis: Construction, transcriptome responses, and applications for producing enzymes and surfactin	24
Metabolic engineering for the utilization of carbohydrate portions of lignocellulosic biomass	24
Recent advances toward the bioconversion of methane and methanol in synthetic methylotrophs	24
CRISPR-based metabolic pathway engineering	24
Design of a genetically encoded biosensor to establish a high-throughput screening platform for L-cysteine overproduction	24
Protocatechuate overproduction by Corynebacterium glutamicum via simultaneous engineering of native and heterologous biosynthetic pathways	24
High-throughput screening for high-efficiency small-molecule biosynthesis	24
A “push-pull-restrain” strategy to improve citronellol production in Saccharomyces cerevisiae	24
Reprint of Organic waste conversion through anaerobic digestion: A critical insight into the metabolic pathways and microbial interactions	23
CRISPR-derived genome editing technologies for metabolic engineering	23
Microbial synthesis of wax esters	23
Metabolic engineering of β-oxidation to leverage thioesterases for production of 2-heptanone, 2-nonanone and 2-undecanone	23
Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone	23
Crabtree/Warburg-like aerobic xylose fermentation by engineered Saccharomyces cerevisiae	23
Targeting cofactors regeneration in methylation and hydroxylation for high level production of Ferulic acid	22
Reverse engineering of fatty acid-tolerant Escherichia coli identifies design strategies for robust microbial cell factories	22
Four-carbon dicarboxylic acid production through the reductive branch of the open cyanobacterial tricarboxylic acid cycle in Synechocystis sp. PCC 6803	22
Engineering yeast for high-level production of diterpenoid sclareol	22
Multilevel metabolic engineering of Bacillus licheniformis for de novo biosynthesis of 2-phenylethanol	22
Engineered citrate synthase alters Acetate Accumulation in Escherichia coli	21
Synthetic metabolic pathways for conversion of CO2 into secreted short-to medium-chain hydrocarbons using cyanobacteria	21
Metabolic engineering of Escherichia coli for the production of benzoic acid from glucose	21
Model reduction of genome-scale metabolic models as a basis for targeted kinetic models	21
Biological upgrading of pyrolysis-derived wastewater: Engineering Pseudomonas putida for alkylphenol, furfural, and acetone catabolism and (methyl)muconic acid production	21

Cycling between growth and production phases increases cyanobacteria bioproduction of lactate	21
Microbial production of riboflavin: Biotechnological advances and perspectives	20
Pyruvate metabolism redirection for biological production of commodity chemicals in aerobic fungus Aspergillus oryzae	20
Production of 1-octanol in Escherichia coli by a high flux thioesterase route	20
Engineering precursor supply for the high-level production of ergothioneine in Saccharomyces cerevisiae	20
Engineering Yarrowia lipolytica for the selective and high-level production of isocitric acid through manipulation of mitochondrial dicarboxylate–tricarboxylate carriers	20
Adaptive laboratory evolution and reverse engineering enhances autotrophic growth in Pichia pastoris	20
Improved methylation in E. coli via an efficient methyl supply system driven by betaine	20
Improved production of human hemoglobin in yeast by engineering hemoglobin degradation	20
Synthetic metabolic channel by functional membrane microdomains for compartmentalized flux control	20
Dynamic consolidated bioprocessing for direct production of xylonate and shikimate from xylan by Escherichia coli	20
Design of mutualistic microbial consortia for stable conversion of carbon monoxide to value-added chemicals	20
Novel two-stage processes for optimal chemical production in microbes	19
A novel WRKY34-bZIP3 module regulates phenolic acid and tanshinone biosynthesis in Salvia miltiorrhiza	19
Construction of a carbon-conserving pathway for glycolate production by synergetic utilization of acetate and glucose in Escherichia coli	19
Role of cyanobacterial phosphoketolase in energy regulation and glucose secretion under dark anaerobic and osmotic stress conditions	19
Rational engineering of transcriptional riboswitches leads to enhanced metabolite levels in Bacillus subtilis	19
A manipulation of carotenoid metabolism influence biomass partitioning and fitness in tomato	19
Metabolic engineering of tomato fruit enriched in L-DOPA	19
Applied evolution: Dual dynamic regulations-based approaches in engineering intracellular malonyl-CoA availability	18
High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deleting genes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and 2,3-dimethylglycerate	18
Reconstructing a recycling and nonauxotroph biosynthetic pathway in Escherichia coli toward highly efficient production of L-citrulline	18
Integrated rational and evolutionary engineering of genome-reduced Pseudomonas putida strains promotes synthetic formate assimilation	18
A quantitative metabolic analysis reveals Acetobacterium woodii as a flexible and robust host for formate-based bioproduction	18
Regulatory control circuits for stabilizing long-term anabolic product formation in yeast	18
Precise promoter integration improves cellulose bioconversion and thermotolerance in Clostridium cellulolyticum	18
A SWEET surprise: Anaerobic fungal sugar transporters and chimeras enhance sugar uptake in yeast	18
Metabolic engineering of Saccharomyces cerevisiae for gram-scale diosgenin production	18
High-yield whole cell biosynthesis of Nylon 12 monomer with self-sufficient supply of multiple cofactors	17
Improving the production of NAD+ via multi-strategy metabolic engineering in Escherichia coli	17
Enhanced targeted DNA methylation of the CMV and endogenous promoters with dCas9-DNMT3A3L entails distinct subsequent histone modification changes in CHO cells	17
Syntrophic co-culture of a methanotroph and heterotroph for the efficient conversion of methane to mevalonate	17
Systematic evaluation of parameters for genome-scale metabolic models of cultured mammalian cells	17
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes	17
Engineered transient and stable overexpression of translation factors eIF3i and eIF3c in CHOK1 and HEK293 cells gives enhanced cell growth associated with increased c-Myc expression and increased reco	17
Identification of novel metabolic engineering targets for S-adenosyl-L-methionine production in Saccharomyces cerevisiae via genome-scale engineering	17
Harnessing plasmid replication mechanism to enable dynamic control of gene copy in bacteria	16
Stepwise genetic engineering of Pseudomonas putida enables robust heterologous production of prodigiosin and glidobactin A	16
Rational orthologous pathway and biochemical process engineering for adipic acid production using Pseudomonas taiwanensis VLB120	16
Biosensor-informed engineering of Cupriavidus necator H16 for autotrophic D-mannitol production	16
Characterization and directed evolution of propionyl-CoA carboxylase and its application in succinate biosynthetic pathway with two CO2 fixation reactions	16
Paving the way for synthetic C1 - Metabolism in Pseudomonas putida through the reductive glycine pathway	16
Synergistic experimental and computational approach identifies novel strategies for polyhydroxybutyrate overproduction	16
Dynamic flux regulation for high-titer anthranilate production by plasmid-free, conditionally-auxotrophic strains of Pseudomonas putida	16
Improving growth of Cupriavidus necator H16 on formate using adaptive laboratory evolution-informed engineering	16
Development of a nonauxotrophic L-homoserine hyperproducer in Escherichia coli by systems metabolic engineering	16
Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction	16
Systems engineering of Escherichia coli for high-level shikimate production	16
Assembly of pathway enzymes by engineering functional membrane microdomain components for improved N-acetylglucosamine synthesis in Bacillus subtilis	15
Global metabolic rewiring of the nonconventional yeast Ogataea polymorpha for biosynthesis of the sesquiterpenoid β-elemene	15
Multi-level rebalancing of the naringenin pathway using riboswitch-guided high-throughput screening	15
Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion	15
Overexpression of transcription factor BLIMP1/prdm1 leads to growth inhibition and enhanced secretory capacity in Chinese hamster ovary cells	15
Membrane transporter identification and modulation via adaptive laboratory evolution	15
Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics	15
Systems metabolic engineering of Corynebacterium glutamicum for the efficient production of β-alanine	15
Overproduction of medicinal ergot alkaloids based on a fungal platform	15
Metabolic engineering of the acid-tolerant yeast Pichia kudriavzevii for efficient L-malic acid production at low pH	15
Biosensor-assisted evolution for high-level production of 4-hydroxyphenylacetic acid in Escherichia coli	15
Engineering of a robust Escherichia coli chassis and exploitation for large-scale production processes	15
Improved biotin, thiamine, and lipoic acid biosynthesis by engineering the global regulator IscR	15
Punicic acid production in Brassica napus	14
Manipulating fatty-acid profile at unit chain-length resolution in the model industrial oleaginous microalgae Nannochloropsis	14
Active and machine learning-based approaches to rapidly enhance microbial chemical production	14
High titer methyl ketone production with tailored Pseudomonas taiwanensis VLB120	14
Systems metabolic engineering of Corynebacterium glutamicum eliminates all by-products for selective and high-yield production of the platform chemical 5-aminovalerate	14
Engineering the thermotolerant industrial yeast Kluyveromyces marxianus for anaerobic growth	14
A synthetic C2 auxotroph of Pseudomonas putida for evolutionary engineering of alternative sugar catabolic routes	14
The heterologous production of terpenes by the thermophile Parageobacillus thermoglucosidasius in a consolidated bioprocess using waste bread	14
Biosensor-assisted titratable CRISPRi high-throughput (BATCH) screening for over-production phenotypes	14
Multi-level metabolic engineering of Pseudomonas mutabilis ATCC31014 for efficient production of biotin	14
Microbial production of human milk oligosaccharide lactodifucotetraose	14
Introduction of NADH-dependent nitrate assimilation in Synechococcus sp. PCC 7002 improves photosynthetic production of 2-methyl-1-butanol and isobutanol	14
High-throughput enrichment of temperature-sensitive argininosuccinate synthetase for two-stage citrulline production in E. coli	14
Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum	14
Rewiring cyanobacterial photosynthesis by the implementation of an oxygen-tolerant hydrogenase	13
Two-stage dynamic deregulation of metabolism improves process robustness & scalability in engineered E. coli.	13
Biosynthesis of diverse α,ω-diol-derived polyhydroxyalkanoates by engineered Halomonas bluephagenesis	13
Using biopolymer bodies for encapsulation of hydrophobic products in bacterium	13
Genome-scale metabolic modeling of P. thermoglucosidasius NCIMB 11955 reveals metabolic bottlenecks in anaerobic metabolism	13
Transient vitamin B5 starving improves mammalian cell homeostasis and protein production	13
Quantifying the propagation of parametric uncertainty on flux balance analysis	13
Development of Methylorubrum extorquens AM1 as a promising platform strain for enhanced violacein production from co-utilization of methanol and acetate	13
Short and long-read ultra-deep sequencing profiles emerging heterogeneity across five platform Escherichia coli strains	13
Combinational quorum sensing devices for dynamic control in cross-feeding cocultivation	13
Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals	13
In vivo directed enzyme evolution in nanoliter reactors with antimetabolite selection	13
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins	13
Engineering Bacteroides thetaiotaomicron to produce non-native butyrate based on a genome-scale metabolic model-guided design	13
Triggering the stringent response enhances synthetic methanol utilization in Escherichia coli	13
Metabolic engineering of the oleaginous alga Nannochloropsis for enriching eicosapentaenoic acid in triacylglycerol by combined pulling and pushing strategies	13
Sustainable production of genistin from glycerol by constructing and optimizing Escherichia coli	12
Investigation of putative genes for the production of medium-chained acids and alcohols in autotrophic acetogenic bacteria	12
Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction	12
In-planta production of the biodegradable polyester precursor 2-pyrone-4,6-dicarboxylic acid (PDC): Stacking reduced biomass recalcitrance with value-added co-product	12