OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Medicinal Food is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Decreased Docosahexaenoic Acid Levels in Serum of HIV Carrier Patients	41
The Effect of Mastic Chios Supplementation in Inflammatory Bowel Disease: A Systematic Literature Review	40
Therapeutic Plants with Immunoregulatory Activity and Their Applications: A Scientific Vision of Traditional Medicine in Times of COVID-19	25
Effects of Bonito Elastin HC on Skin Dryness, Wrinkles, and Pigmentation In Vitro and In Vivo	22
Umbilicaria esculenta Extract Exhibits Antiwrinkle Activity by Suppressing ErbB2 Phosphorylation	21
Korean Red Ginseng Extract Powder Mitigates Fasting And Postprandial Hyperglycemia in Type 2 Diabetic Mice	21
Actinidia arguta Extract Containing Myo-Inositol Suppresses TNF-α-Induced VCAM-1 Expression and Monocyte Adhesion to Endothelial Cells via Inhibition of the PTEN/Akt/GSK-3β	19
Chemometric and Dereplication Analyses of the Anti-Staphylococcus aureus Strains Activity of Salvia hispanica L. Seeds	19
Ginkgolic Acid Suppresses Nasopharyngeal Carcinoma Growth by Inducing Apoptosis and InhibitingAKT/NF-κBSignaling	18
Comparative Study of Two Erythronium sibiricum Bulb Polysaccharide Fractions in Alleviating Airway Remodeling by Affecting Autophagy and Apoptosis	18
Soy Sauce Lowers Body Weight and Fat Mass in High-Fat Diet-Induced Obese Rats	17
Dietary Supplementation of Carob and Whey Modulates Gut Morphology, Hemato-Biochemical Indices, and Antioxidant Biomarkers in Rabbits	16
Phosphodiesterase 4 mRNA Level Suppression is Important for Extract of Black Carrot to Protect Against Hepatic Injury Induced by Ethanol	16
Acknowledgment of Reviewers 2021	16
In Vitro and In Vivo Models for the Development of Hair Growth Materials By Regulating the β-Catenin Signaling Pathways	16
Hepatic Proteomics Analysis of Nonalcoholic Fatty Liver Disease Obese Rat Model After Short- and Long-Term Soy Protein Isolate Feeding	15
Unraveling the Potential Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Mechanisms of Ginger by Computational Target Fishing	15
A Systematic Review Evaluating Cinnamon's Effects on Glucose Utilizing a Ranking System to Assess Bias and Study Quality	14
Fermented Strawberry (Fragaria x Ananassa Duch.) Mitigates Renal Fibrosis in a Unilateral Ureteral Obstruction Model by Reducing Inflammation, Oxidative Stress, and Regulating Smad Signaling	14
Protective Effects of Cudrania tricuspidata Against Helicobacter pylori-Induced Inflammation in C57BL/6 Mice	14
Prebiotic Potential of Goji Berry (Lycium barbarum) in Improving Intestinal Integrity and Inflammatory Profiles via Modification of the Gut Microbiota in High-Fat Diet-Fed Rats	14
Gamma-Aminobutyric Acid in Rice Bran Extract Exerts Antistress Effects in Mouse Models with Depressive-Like Behaviors	14
Anti-Obesity Effect of Jeju Roasted Citrus Peel Extract in High-Fat Diet-Induced Obese Mice and 3T3-L1 Adipocytes Via Lipid Metabolism Regulation	14
Intermittent Versus Continuous Wild Blueberry Feeding Alters Inflammation and Behavior in Aged Male Rats	13
Laxative Effect of Crataegus azarolus Leaves Decoction Extract Against Loperamide-Induced Constipation and Oxidative Stress in Rats	13

Neurological Restorative Effects of (-)-Epicatechin in a Model of Gulf War Illness	12
Antidiabetic Activity of Xoconostle Fruit fromOpuntia matudaeScheivar in Mice	12
Pharmacological Evaluation of Respiratory Safety Following a Single Intravenous Administration of Theophylline in Sprague–Dawley Rats	12
Nigella sativa-Fortified Cookies Ameliorate Oxidative Stress, Inflammatory and Immune Dysfunction in Plasmodium berghei-Infected Murine Model	12
Hovenia dulcis Thunb. Fruit Extract Attenuates Psoriatic Skin Inflammation in Tumor Necrosis Factor-α-Stimulated Human Keratinocyte HaCaT Cells In Vitro	11
Effects of Pear Extracts on Microbiome and Immunocytokines to Alleviate Air Pollution-Related Respiratory Hypersensitivity	11
Scrophularia buergeriana Extract (Brainon) Attenuates Neuroinflammation in BV-2 Microglia Cells and Promotes Neuroprotection in SH-SY5Y Neuroblastoma Cells	11
Association Between Consumption of Foods Containing Vitamin D and All-Cause Mortality in Korea	11
Sesamin Attenuates Obesity-Associated Nonalcoholic Steatohepatitis in High-Fat and High-Fructose Diet-Fed Mice	11
Is Cottonseed Oil the Next Healthy Oil?	11
Thyme (Thymus vulgaris [Lamiaceae]) Leaves Inhibit Contraction of the Nonpregnant Mouse Uterus	11
Lactobacillus gasseri BNR17 Ameliorates Dexamethasone-Induced Muscle Loss in BALB/c Mice and C2C12 Myotubes	10
The Effect of Royal Jelly on Telomere Length and Some Biochemical Parameters in Wistar Albino Rats with Liver Damage Caused by Carbon Tetrachloride	10
Natural Honey Proteins Prevent Diet-Induced Obesity and Metabolic Disorders in Rats	10
Salvia hispanica L. Seed Oil: Effect on Cell Viability in Colon Cancer Line Caco2 and Breast Cancer Line MCF7	10
Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α	10
Evaluation of the Consumption of Fruits and Vegetables by Phenylketonurics in the Metabolic Control of Phenylalanine: An Integrative Review	10
Acmella oleracea Is a Medicinal Plant That Decreases Chymase Activity, Oxidative Stress, and Inflammation: Possible Role in the Adjuvant Treatment of COVID-19	10
Melinjo (Gnetum gnemon L) Extract Attenuates Colonic Inflammation in a Mouse Colitis Model by Regulating the AMPK/NFκB/Sirt1 Pathway	10
Black Mulberry Extract Elicits Hepatoprotective Effects in Nonalcoholic Fatty Liver Disease Models by Inhibition of Histone Acetylation	10
High-Fat Diet with LyophilizedAcrocomia aculeataPulp Increases High-Density Lipoprotein-Cholesterol Levels and Inhibits Adipocyte Hypertrophy in Mice	10
Metabolites Generated from Foods Through Lactic Fermentation and Their Benefits on the Intestinal Microbiota and Health	9
Immune Boosting Effect of Limosilactobacillus Reuteri in Immunocompetent C57BL/6J Mice	9
Antinociceptive and Anti-Inflammatory Properties of Cannabidiol Alone and in Combination with Standardized Bioflavonoid Composition	9
Effect of GHX02 on an Asthma–Rhinitis Mouse Model Induced by Ovalbumin and Diesel Particulate Matter	9
Silymarin Prevents High-Fat Diet-Induced Muscle Atrophy by Regulating Protein Degradation and Synthesis in Mice	8
Application of Metabolomics and Microbiome Analysis for Revealing the Endogenous Mechanism of Baizhu Xiaozhong San in Postpartum Rats with Spleen-qi Deficiency	8
Correction to: Lactic Acid Bacteria and Natural Product Complex Ameliorates Ovalbumin-Induced Airway Hyperresponsiveness in Mice, by Nam et al. J Med Food 2021; 24(5):517–526. doi: 10	8
Pumpkin Seed Extracts Inhibit Proliferation and Induce Autophagy in PC-3 Androgen Insensitive Prostate Cancer Cells	8
Butein-Enriched Fractions of Butea monosperma (Lam.) Taub. Flower Decrease Weight Gains and Increase Energy Expenditure in High-Fat Diet-Induced Obese Mice	8
Garlic Scape (Allium sativum L.) Extract Decreases Adipogenesis by Activating AMK-Activated Protein Kinase During the Differentiation in 3T3-L1 Adipocytes	8
The Short-Term Effect of Olive Oil Extract Enriched with Hydroxytyrosol on Cardiovascular Function	7
Neuroprotective Potential of Brown Seaweed Phytochemicals in Rodent Models of Cerebral Ischemia	7
Cytotoxicity Screening of Sterculia striata A.St.-Hil. & Naudin (Chichá) and Arachis hypogaea L. (Peanut) and Comparative Chemical Profiles Before and After in Vitro Digestion	7
Rosa Roxburghii Tratt Polysaccharides Prevent Alzheimer’s Disease-Like Cognitive Dysfunctions and Pathology in Rats by Regulating the Microbiota-Gut-Brain Axis and Oxidative Stress	7
Antioxidant and Hepatoprotective Effect ofRosa davuricaPall Seed Oil on CCl₄-Induced Acute Liver Injury in Mice	7
Therapeutic Potential of Artichoke in the Treatment of Fatty Liver: A Systematic Review and Meta-Analysis	7
Ameliorative Effects of Fermented Red Ginseng Extract on Muscle Atrophy in Dexamethasone-Induced C2C12 Cell And Hind Limb-Immobilized C57BL/6J Mice	7
Efficacy and Tolerability of Ich Nieu Khang Dietary Supplement for Overactive Bladder	7
Effects of the Use of Curcumin on Ulcerative Colitis and Crohn's Disease: A Systematic Review	7
The Effect of Prebiotics and Probiotics (Synbiotics) on Weight Loss and Biochemical Parameters in Obese Individuals	7
Lowering of Blood Glucose Levels with the Peptide Mixture Deglusterol in In Vitro and In Vivo Models	7
Cardiomodulatory and Antioxidative Potentials of Almond–Citrus Peel Fortified Shortbread in High Fat Diet/L-NAME-Induced Hyperlipidemic–Hypertensive Rats	7
Vitamin A and Diabetes	7
Prefrontal Cortex and Hippocampus Inflammation in Mice Fed High-Carbohydrate or High-Fat Diets	7
Lactobacillus paracasei HY7015 Promotes Hair Growth in a Telogenic Mouse Model	7
Systemic/Immune-Modulation of Olea europaea Leaf Extract in Fetuses of Alloxan-Induced T1 Diabetic Rats	6
Artichoke Extract Directly Suppresses Inflammation and Apoptosis in Hepatocytes During the Development of Non-Alcoholic Fatty Liver Disease	6
Antidiarrheal, Antimicrobial, and Antioxidant Properties of the Aqueous Extract of Tunisian Persimmon (Diospyros kaki Thunb.) Fruits	6
Gastroprotective Role of Fruit Extracts in Gastric Damage Induced by Non-Steroidal Anti-Inflammatory Drugs: A Systematic Review	6

The Role of Garlic in Metabolic Diseases: A Review	6
In Vivo Chemosuppressive Effects of Kolaviron on 7,12-Dimethylbenzanthracene-Induced Mammary Lesions are Associated with Changes in Levels of Estrogen Receptor-α, CYP 1A1, Proinflammatory Cytok	6
Natural Products as Modulators of Mitochondrial Dysfunctions Associated with Cardiovascular Diseases: Advances and Opportunities	6
Effect of Collagen Peptide-Chelated Zinc Nanoparticles From Pufferfish Skin on Zinc Bioavailability in Rats	6
High Iron Consumption Modifies the Hepatic Transcriptome Related to Cholesterol Metabolism	6
Functional Observation Battery Test for Single Intravenous Caffeine Exposure in Male ICR Mice	6
Citric Acid-Enriched Extract of RipePrunus mume(Siebold) Siebold & Zucc. Induces Laxative Effects by Regulating the Expression of Aquaporin 3 and Prostaglandin E₂in Rats with Lop	6
Antioxidant and Anti-Inflammatory Activities of Zingiber montanum Oil in HepG2 Cells and Lipopolysaccharide-Stimulated RAW 264.7 Macrophages	6
Panax Notoginseng Saponins Regulate Angiogenic Cytokines Through the PI3K/AKT/mTOR Signaling Pathway to Promote Fracture Healing in Ovariectomized Rats	6
Suppressive Effects of Arriheuk Wheat Sprout Extract on Muscle Atrophy in Dexamethasone-Induced C2C12 Myotubes and a Mouse Model	6
β-Glucan-Rich Extract of Gray Oyster Mushroom, Pleurotus pulmonarius, Improves Object Recognition Memory and Hippocampus Morphology in Mice Fed a High-Fat Diet	6
Sweetly Improving Sugars? Reviewing Cinnamon's Effects on Blood Glucose	6
Corydalis yanhusuo Polysaccharides Ameliorate Chronic Stress-Induced Depression in Mice through Gut Microbiota-Derived Short-Chain Fatty Acid Activation of 5-Hydroxytryptamine Signaling	6
Maillard Reaction Products and Phenolic Compounds from Roasted Peanut Flour Extracts Prevent Scopolamine-Induced Amnesia Via Cholinergic Modulation and Antioxidative Effects in Mice	6
Tyrosol: Repercussion of the Lack of a Hydroxyl-Group in the Response of MCF-7 Cells to Hypoxia	6
Capsicum annuum var. abbreviatum Induces a Macrophage M2-Like Phenotype Mediated by Nrf2/HO-1 in LPS-Stimulated Macrophages	6
Chrysanthemum Zawadskii Var. and Platycodon Grandifloras Extract Mixture Protects Against Lipopolysaccharide-Induced Pulmonary Inflammation and Cyclophosphamide-Induced Immune Deficiency	6
Correction to: Glycemic Index and Glycemic Load of Two Dishes Cooked with Alache (Anoda cristata) and Chaya (Cnidoscolus aconitifolius) Plants from the Traditional Mexican Diet by	6
Portulaca Oleracea L. Phenolic Amide Methyl (3,4,5-Trimethoxybenzoyl) Valylprolinate Attenuates Diethylhexyl Phthalate-Induced Human Umbilical Vein Endothelial Cells’ Inflammation Through NLRP3 and NF	6
Myrciaria dubia Juice (camu-camu) Exhibits Analgesic and Antiedematogenic Activities in Mice	6
Crude Extracts of Pleurotus Spp. and the Presence of Their Proteins in the Ovicidal and Larvicidal Activity of Haemonchus contortus	6
Hypoglycemic and Hypolipogenic Action of Acetic Acid and Monascus-Fermented Grain Vinegar: A Comparative Study	5
Anti-Allergic Effects of the Subcritical Water Extract Powder of Citrus unshiu in Mouse and Guinea Pig Models	5
Cruciferous Plant Extracts, Their Isothyocianate or Indol Derivatives, and Their Effect on Cellular Viability of Breast Cancer Cell Lines	5
Acknowledgment of Reviewers 2024	5
Protective Effect of Whole Wheat on Muscle Atrophy in C2C12 Cells via Akt/FoxO1 Signaling Pathways	5
KGR-BG1, a Standardized Korean Black Ginseng Extract, Has No Significant Effects on Head or Face Temperature Compared with Korean Red Ginseng Extract and a Placebo	5
Tucumã (Astrocaryum aculeatum) Prevents Oxidative and DNA Damage to Retinal Pigment Epithelium Cells	5
Evidence of the Cardioprotective Effects of Aloysia polystachya in Isoproterenol-Induced Myocardial Infarction in Rats	5
Lactic Acid Bacteria and Natural Product Complex Ameliorates Ovalbumin-Induced Airway Hyperresponsiveness in Mice	5
Study of the Pharmacodynamic Material Basis and Mechanisms of the Action of Fubai Chrysanthemum in Relieving Visual Fatigue	5
Buttermilk and Whey as Functional Foods to Ameliorate Clindamycin-Induced Changes in Mouse Intestine: Modulation of Intestinal Motility and Toll-like Receptors Expression	5
Research Progress in the Medicine–Food Dual Use of Astragalus for Gastrointestinal Tumors	5
Hibiscus sabdariffa as a Novel Alternative Strategy Against Helicobacter pylori Infection Development to Gastric Cancer	5
Association of Common Foods with Inflammation and Mortality: Analysis from a Large Prospective Cohort Study	5
Impact of Chronic Consumption of Herbal Rooibos on Cardiovascular Function in Adults with Cardiovascular Risk	5
Cichorium glandulosum Ameliorates HFD-Induced Obesity in Mice by Modulating Gut Microbiota and Bile Acids	5
Ameliorative Effect of Myricetin on Nonalcoholic Fatty Liver Disease in ob/ob Mice	5
Hypoglycemic Activity of the Hydroalcoholic Extract of Porophyllum ruderale in CD1 Mice	5
Correction to: Ethyl Acetate Fraction of Abelmoschus manihot (L.) Medic Flowers Exerts Inhibitory Effects Against Oxidative Stress in H₂O₂-Induced HepG2 Cells and D-Galact	5
Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial	5
Savory Cracker Development for Blood Glucose Control and Management: Glycogen Storage Diseases	5
Effects of Krill Oil and Coconut Oil on Behavioral Changes and Inflammatory Markers in Rats with Chronic Unpredictable Mild Stress Induced Depression Model	5
The Anxiolytic-Like Effects of Protocatechuic Acid in an Animal Model of Post-Traumatic Stress Disorder	5
Momordica charantia Bioactive Components: Hypoglycemic and Hypolipidemic Benefits Through Gut Health Modulation	5
Abelmoschus esculentus (Okra) Prevents Insulin Resistance and Restores Neuron Autophagy by Regulating Dipeptidyl Peptidase-4 and Thus Improving Hippocampal Function	5
Neuroprotective Effects of Zerumbone on H₂O₂-Induced Oxidative Injury in Human Neuroblastoma SH-SY5Y Cells	5
Anticancer Effects of Washed-Dehydrated Solar Salt Doenjang on Colon Cancer-Induced C57BL/6 Mice	5
Gastroprotective and Antioxidant Properties of Trigonella foenum graecum Seeds Aqueous Extract (Fenugreek) and Omeprazole Against Ethanol-Induced Peptic Ulcer	4
Anti-Obesity Effect of Porcine Collagen Peptide in 3T3-L1 Adipocytes and High-Fat Diet-Fed Mice by Regulating Adipogenesis	4
Antioxidant Properties of Salvia officinalis Decoction Extract and Mechanism of Its Protective Effects on Ethanol-Induced Liver and Kidney Injuries	4
Partial Replacement of High-Fat Diet with Beef Tallow Attenuates Dyslipidemia and Endoplasmic Reticulum Stress in db/db Mice	4
Tamarixetin Abrogates Adipogenesis Through Inhibiting p300/CBP-Associated Factor Acetyltransferase Activity in 3T3-L1 Preadipocyte Cells	4
Effects of Consuming Fermented Fish (Surströmming) on the Fecal Microflora in Healthy Individuals	4
Therapeutic Potential of Brassica oleracea and Raphanus sativus Aqueous Extracts on a Prediabetic Rat Model	4
Phenolic Composition, Toxicity Potential, and Antimicrobial Activity of Licania rigida Benth (Chrysobalanaceae) Leaf Extracts	4
Agave tequilana Counteracts Chronic Hypertension and Associated Vascular Damage	4
Cytotoxic and Antitumoral Effects of Methanolic Extracts of Avocado Fruit Mesocarp in Colorectal Cancer Cell Line HT29	4
Comprehensive Investigation of Homology and Heterogeneity Between Aurantii Fructus and Aurantii Fructus Immaturus Using Chemometrics Combined with Network Pharmacology	4
Myo-Inositol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy by Inhibiting PI3K/AKT Activation	4
Beneficial Effects of Flavonoids on Skeletal Muscle Health: A Systematic Review and Meta-Analysis	4
UP360, a Standardized Composition from Extracts of Aloe barbadense, Poria cocos, and Rosemary officinalis Protected Against Sepsis and Mitigated Acute Lung Injury in Murine Models	4
Red Ginseng Extract and γ-Aminobutyric Acid Synergistically Enhance Immunity Against Cancer Cells and Antitumor Metastasis Activity in Mice	4
Bacillus amyloliquefaciens SCGB1 Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Immune Regulation	4
Linseed Oil Attenuates Liver Inflammation, Fatty Acid Accumulation, and Lipid Distribution in Periportal and Perivenous Hepatocytes Induced by a High-Carbohydrate Diet in Mice	4
An Open-Label Pilot Study on Macumax Supplementation for Dry-Type Age-Related Macular Degeneration	4
Aruncus Dioicus Var. Kamtschaticus Extract Prevents Ocular Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress In Vitro	4
Angelica keiskei Root Extract Attenuates Bile Duct Ligation-Induced Liver Injury in Mice	4
Controlling Intestinal Infections and Digestive Disorders Using Probiotics	4
Antivirulence Activity of a Dietary Phytochemical: Hibiscus Acid Isolated from Hibiscus sabdariffa L. Reduces the Virulence of Pseudomonas aeruginosa in a Mouse Infection Model	4
β-Escin and Chokeberry Fruit Extract Supplementation in Smokers as Potential anti-Inflammatory Protection—a Pilot Proof-of-Concept Study	4
Exploring the Molecular Mechanisms of Herbs in the Treatment of Hyperlipidemia Based on Network Pharmacology and Molecular Docking	4
Fructus Mume (Wu Mei) Attenuates Acetic Acid-Induced Ulcerative Colitis by Regulating Inflammatory Cytokine, Reactive Oxygen Species, and Neuropeptide Levels in Model Rats	4
YES-10 Improves Stress, Tension, and Fatigue by Reducing Cortisol and IL-6 Levels	4
The Perceived Impact of Ashwagandha on Stress, Sleep Quality, Energy, and Mental Clarity for College Students: Qualitative Analysis of a Double-Blind Randomized Control Trial	4
Inhibitory Effects of Wheat Sprouts Extract on RANKL-Induced Osteoclast Differentiation via Suppressing MAPK and NFATc1 Signaling Pathways	4
Effects of a Mixture of Humulus japonicus on Longitudinal Bone Growth in Hypophysectomized Rats	4
A Food Supplement with Antioxidative Santa Herba Extract Modulates Energy Metabolism and Contributes to Weight Management	4