Toxicological Sciences

Article	Citations
Correction to: Reducing uncertainties in quantitative adverse outcome pathways by analysis of thyroid hormone in the neonatal rat brain	82
Erratum to: An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability	81
Effect of third-party components on emissions from a pod style electronic cigarette	79
Dictyostelium discoideum:An Alternative Nonanimal Model for Developmental Toxicity Testing	72
Cadmium inhibits calcium activity in hippocampal CA1 neurons of freely moving mice	59
Early detection of genotoxic hepatocarcinogens in rats using γH2AX and Ki-67: prediction by machine learning	59
Comment on: “Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis”	54
Low-dose inhalation exposure to trichloroethylene induces dopaminergic neurodegeneration in rodents	49
Mono-(2-ethylhexyl) phthalate reversibly disrupts the blood-testis barrier in pubertal rats	47
Haloacetamides exacerbate non-alcoholic fatty liver disease induced by a high-fat diet in C57BL/6J mice	46
Quantitative and qualitative concordance between clinical and nonclinical toxicity data	44
DNA adducts form in mouse lung and liver after oral naphthalene exposure	43
Kupffer cell expression of macrophage receptor with collagenous structure modulates macrophage gene induction and limits acute liver injury	42
The Foam Cell Formation Associated With Imbalanced Cholesterol Homeostasis Due to Airborne Magnetite Nanoparticles Exposure	40
Correction to: Repeated exposure to eucalyptus wood smoke alters pulmonary gene and metabolic profiles in male Long-Evans rats	40
Low-Dose Cadmium Potentiates Metabolic Reprogramming Following Early-Life Respiratory Syncytial Virus Infection	40
Dolutegravir Impairs Stem Cell-Based 3D Morphogenesis Models in a Manner Dependent on Dose and Timing of Exposure: An Implication for Its Developmental Toxicity	39
The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior	36
Parenteral nutrition-associated liver injury: clinical relevance and mechanistic insights	36
Circ_0089282 inhibits carbon black nanoparticle-induced DNA damage by promoting DNA repair protein in the lung	35
Evaluation of neurotoxicity and the role of oxidative stress of cobalt nanoparticles, titanium dioxide nanoparticles, and multiwall carbon nanotubes in Caenorhabditis elegans	35
Multigenerational Effects of an Environmentally Relevant Phthalate Mixture on Reproductive Parameters and Ovarian miRNA Expression in Female Rats	34
Effects of mixed metal exposure on MRI metrics in basal ganglia	34
Blockade of Voltage-Dependent K+ Channels by Benztropine, a Muscarinic Acetylcholine Receptor Inhibitor, in Coronary Arterial Smooth Muscle Cells	33
Persistent γ-H2AX Formation and Expression of Stem Cell Markers in N-Butyl-N-(4-Hydroxybutyl)Nitrosamine-Induced Bladder Carcinogenesis in Rats	32

In vitro modeling of the post-ingestion bioaccessibility of per- and polyfluoroalkyl substances sorbed to soil and house dust	31
Prenatal prednisone exposure impacts liver development and function in fetal mice and its characteristics	31
Effects of combustible cigarettes and heated tobacco products on immune cell-driven inflammation in chronic obstructive respiratory diseases	30
Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity	29
Adolescent exposure to a mixture of per- and polyfluoroalkyl substances (PFAS) depletes the ovarian reserve, increases ovarian fibrosis, and alters the Hippo pathway in adult female mice	27
A mixture of organophosphate esters sex-specifically impacts monocyte–macrophages in Sprague-Dawley rats	26
Adapting Existing Toxicokinetic Models to Relate Perfluoroalkyl and Polyfluoroalkyl Intake to Biomarkers in Humans	26
Steatotic liver disease induced by TCPOBOP-activated hepatic constitutive androstane receptor: primary and secondary gene responses with links to disease progression	26
A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury	25
Quantitation and identification of microplastics accumulation in human placental specimens using pyrolysis gas chromatography mass spectrometry	23
Comparative toxicological assessment of 2 bisphenols using a systems approach: evaluation of the behavioral and transcriptomic responses of Danio rerio to bisphenol A and tetrabromobisphenol A	22
Preclinical cardiovascular safety assessment of pharmacology-toxicology relationship for a set of novel kinase inhibitors	21
Pluripotent stem cells for target organ developmental toxicity testing	21
Cellular and molecular responses to ethyl-parathion in undifferentiated SH-SY5Y cells provide neurotoxicity pathway indicators for organophosphorus impacts	20
Chronic arsenic exposure affects stromal cells and signaling in the small intestine in a sex-specific manner	20
Advances in Assessing Hazard and Risk to Emerging Threats and Emergency Response: Comparing and Contrasting Efforts of 3 Federal Agencies	20
Caveolin-1 and Its Functional Peptide CSP7 Affect Silica-Induced Pulmonary Fibrosis by Regulating Fibroblast Glutaminolysis	20
MAD2L1 supports MYC-driven liver carcinogenesis in mice and predicts poor prognosis in human hepatocarcinoma	20
Investigating the replacement of carboxylates with carboxamides to modulate the safety and efficacy of platinum(II) thioether cyanide scavengers	19
Quantifying liver-toxic responses from dose-dependent chemical exposures using a rat genome-scale metabolic model	19
Environmental Exposure to Brominated Flame Retardants: Unraveling Endocrine and Mammary Gland Effects That May Increase Disease Risk	19
The role of corticosterone in nevirapine-induced idiosyncratic drug-induced liver injury	18
Antiepileptic drugs are endocrine disruptors for the human fetal testisex vivo	18
Are Non-animal Systemic Safety Assessments Protective? A Toolbox and Workflow	18
Assessment of associations between inhaled formaldehyde and lymphohematopoietic cancer through the integration of epidemiological and toxicological evidence with biological plausibility	18
Bbc3 Loss Enhances Survival and Protein Clearance in Neurons Exposed to the Organophosphate Pesticide Chlorpyrifos	18
Gestational ozone inhalation elicits maternal cardiac dysfunction and transcriptional changes to placental pericytes and endothelial cells	18
Use of Human iPSC-CMs in Nonclinical Regulatory Studies for Cardiac Safety Assessment	18
Integration of new approach methods for the assessment of data-poor chemicals	18
Lead exposure at the feto-maternal interface: a cause for concern for fetal membrane trophoblasts	17
Letter to the editor	17
A systems toxicology approach for identification of disruptions in cholesterol homeostasis after aggregated exposure to mixtures of perfluorinated compounds in humans	17
Trichloroethylene metabolite modulates DNA methylation-dependent gene expression in Th1-polarized CD4+ T cells from autoimmune-prone mice	17
Mechanistic investigation of liver injury induced by BMS-932481, an experimental ɣ-secretase modulator	17
Thank You, ToxSci 2024 Reviewers	17
Long-lasting developmental effects in rat offspring after maternal exposure to acetamiprid in the drinking water during gestation	17
Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate	16
Bone morphogenetic protein 4 is involved in cadmium-associated bone damage	16
Formaldehyde and the transient receptor potential ankyrin-1 contribute to electronic cigarette aerosol-induced endothelial dysfunction in mice	16
Genetic background in the rat affects endocrine and metabolic outcomes of bisphenol F exposure	16
Pharmacokinetic analysis of nicotine and its metabolites (cotinine and trans-3′-hydroxycotinine) in male Sprague-Dawley rats following nose-only inhalation, oral gavage, and intravenous infusio	15
Bayesian refinement of a physiologically based pharmacokinetic model for ethylbenzene pharmacokinetics in mice, rats, and humans	15
CTD tetramers: a new online tool that computationally links curated chemicals, genes, phenotypes, and diseases to inform molecular mechanisms for environmental health	15
A CRISPR-Cas9 mutation in sox9b long intergenic noncoding RNA (slincR) affects zebrafish development, behavior, and regeneration	15
Organophosphate ester flame retardants and plasticizers affect the phenotype and function of HepG2 liver cells	15
Perfluorooctane Sulfonic Acid Disrupts Protective Tight Junction Proteins via Protein Kinase D in Airway Epithelial Cells	14
Technical evaluation and standardization of the human thyroid microtissue assay	14
Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and Ppara-null mouse livers	14
A perspective review on factors that influence mutagenicity in medicinal plants and their health implications	14
Particulate threats: aryl hydrocarbon receptor, alveolar epithelium, environmentally persistent free radicals, and endothelial dysfunction	14

NLRP3 activation in microglia contributes to learning and memory impairment induced by chronic lead exposure in mice	14
Tox-GAN: An Artificial Intelligence Approach Alternative to Animal Studies—A Case Study With Toxicogenomics	14
Correction to: 1,2-Dichloroethane Induces Reproductive Toxicity Mediated by the CREM/CREB Signaling Pathway in Male NIH Swiss Mice	14
Elucidating CD4+ and CD8+ T-cell involvement in patients with vancomycin-induced DRESS	14
Defining VOC signatures of airway epithelial cells with PM2.5 exposure	13
E-Cigarette (E-Cig) Liquid Composition and Operational Voltage Define the In Vitro Toxicity of Δ8Tetrahydrocannabinol/Vitamin E Acetate (Δ8THC/VEA) E-Cig Aerosols	13
Wedelolactone inhibits ferroptosis and alleviates hyperoxia-induced acute lung injury via the Nrf2/HO-1 signaling pathway	13
Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish	13
LncRNA DUXAP10 Upregulation and the Hedgehog Pathway Activation Are Critically Involved in Chronic Cadmium Exposure-Induced Cancer Stem Cell-Like Property	13
Development and Application of an Interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats	13
Relative contributions of endogenous and exogenous formaldehyde to formation of deoxyguanosine monoadducts and DNA-protein crosslink adducts of DNA in rat nasal mucosa	13
Parenchymal and Inflammatory Cell Responses to Single and Repeated Ozone Exposure in Healthy and Surfactant Protein-C Mutant Lung	13
Dermal Exposure to the Immunomodulatory Antimicrobial Chemical Triclosan Alters the Skin Barrier Integrity and Microbiome in Mice	13
Health risk assessment of toxic metals and DNA damage in somatic and germ cells by soil and groundwater of a major cement factory in Nigeria	12
Application of a metabolic network-based graph neural network for the identification of toxicant-induced perturbations	12
Azacitidine and cytarabine induce sustained lymphopenia with abnormal differentiation of common lymphoid progenitors and prolonged suppression of Dnmt3a and Dnmt3b expression in mice	12
Metabolomics of Lung Microdissections Reveals Region- and Sex-Specific Metabolic Effects of Acute Naphthalene Exposure in Mice	12
Cadmium-induced stress: a close look at the relationship between autophagy and apoptosis	12
The herbicide acetochlor causes lipid peroxidation by inhibition of glutathione peroxidase activity	12
ToxPoint: Copper Is the New Showstopper	12
Extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture:in vitrodose-dependent release, chemical content, and microRNA signatures involved in liver health	12
Children with Amalgam Dental Restorations Have Significantly Elevated Blood and Urine Mercury Levels	12
Inhalation of concentrated ambient PM2.5 promotes inactivation of telomerase reverse transcriptase, telomere shortening, and senescence of multiple cell types in mice	12
The association between histopathologic effects and liver weight changes induced in mice and rats by chemical exposures: an analysis of the data from Toxicity Reference Database (ToxRefDB)	12
Using transcriptomic signatures to elucidate individual and mixture effects of inorganic arsenic and manganese in human placental trophoblast HTR-8/SVneo cells	12
ToxPoint: Waste incineration management of plastic materials—an issue of increasing global public health importance	11
Aerosol physicochemical determinants of carbon black and ozone inhalation co-exposure induced pulmonary toxicity	11
The need for good practice in the application of mechanistic constructs in hazard and risk assessment	11
Formation of hepatocyte cytoplasmic inclusions and their contribution to methylcarbamate-induced hepatocarcinogenesis in F344 rats	11
Unraveling the hemolytic toxicity tapestry of peptides using chemical space complex networks	11
Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood lead levels using the Collaborative Cross mouse population	11
Bisphenol A and Male Murine Reproductive System: Finding a Link between Plasticizer and Compromised Health	11
Identification of an adverse outcome pathway (AOP) for chemical-induced craniofacial anomalies using the transgenic zebrafish model	11
Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for in vitro studies of drug transport and toxicity	11
Universal Accessible Biomarkers of Drug-Induced Tissue Injury and Systemic Inflammation in Rat: Performance Assessment of TIMP-1, A2M, AGP, NGAL, and Albumin	11
Associations between per- and polyfluoroalkyl substance exposures and metabolic dysfunction associated steatotic liver disease (MASLD) in adult National Health and Nutrition Examination Survey 2017 to	11
Potential Biomarker Identification by RNA-Seq Analysis in Antibiotic-Related Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A Pilot Study	11
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces liver lipid metabolism disorder via the ROS/AMPK/CD36 signaling pathway	11
Identifying environmental chemicals impacting neurodevelopment using a random mixture-based screening approach	11
Metabolites of Synthetic Cannabinoid 5F-MDMB-PINACA Retain Affinity, Act as High Efficacy Agonists and Exhibit Atypical Pharmacodynamic Properties at CB1 Receptors	11
Development of a physiologically based pharmacokinetic model for flunixin in cattle and swine following dermal exposure	11
Die hard: cell death mechanisms and their implications in nanotoxicology	11
Weight of evidence for cross-species conservation of androgen receptor-based biological activity	10
SETBP1-R54P mutation promotes malignant transformation of cadmium-induced 16HBE cells by down-regulating circ_0007095 expression	10
The Importance of Conventional Toxicological Metrics of Aerosol Characterization	10
Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction	10
Aflatoxin B1 Induces Gut-Inflammation-Associated Fecal Lipidome Changes in F344 Rats	10
Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation	10
Molecular Dosimetry of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer	10
Diet-induced obesity alters the ovarian chemical biotransformation and oxidative stress response proteins both basally and in response to 7,12-dimethylbenz[a]anthracene exposure	10
Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy)	10
Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary	10
Chronic exposure to BDE-47 aggravates acute pancreatitis and chronic pancreatitis by promoting acinar cell apoptosis and inflammation	10
Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity	10
Adrenal Stress Hormone Regulation of Hepatic Homeostatic Function After an Acute Ozone Exposure in Wistar-Kyoto Male Rats	10
The Postnatal Resolution of Developmental Toxicity Induced by Pharmacological Diacylglycerol Acyltransferase 2 (DGAT2) Inhibition During Gestation in Rats	10
Distribution of polybrominated diphenyl ethers (PBDEs) in placental tissues of maternal and fetal origin in exposed Wistar rats and associations with thyroid hormone levels	10
Decision-Making with New Approach Methodologies: Time to Replace Default Uncertainty Factors with Data	10
Gestational Cd Exposure in the CD-1 Mouse Sex-Specifically Disrupts Essential Metal Ion Homeostasis	9
Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in mice	9
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids	9
LC3B-regulated autophagy mitigates zinc oxide nanoparticle-induced epithelial cell dysfunction and acute lung injury	9
Recovered Hepatocytes Promote Macrophage Apoptosis Through CXCR4 After Acetaminophen-Induced Liver Injury in Mice	9
Inhaled toxicants and pulmonary lipid metabolism: biological consequences and therapeutic interventions	9
St. John’s Wort Exacerbates Acetaminophen-Induced Liver Injury by Activation of PXR and CYP-Mediated Bioactivation	9
A Sulfonyl Azide-Based Sulfide Scavenger Rescues Mice from Lethal Hydrogen Sulfide Intoxication	9
Corrigendum to: Torsadogenic Action of Cisapride, dl-Sotalol, Bepridil, and Verapamil Analyzed by the Chronic Atrioventricular Block Cynomolgus Monkeys: Comparison With That Reported in the CiPA In Si	9
Behavior and brain size of larval zebrafish exposed to environmentally relevant concentrations of beta-methylamino-l-alanine	9
Exploring the effects of topoisomerase II inhibitor XK469 on anthracycline cardiotoxicity and DNA damage	9
Serum glutamate dehydrogenase activity enables sensitive and specific diagnosis of hepatocellular injury in humans	9
Assessing Safety Without Animal Testing: The Road Ahead	9
Correction: Ammonium perchlorate: serum dosimetry, neurotoxicity, and resilience of the neonatal rat thyroid system	9
Single-cell transcriptomics unveiled that early life BDE-99 exposure reprogrammed the gut-liver axis to promote a proinflammatory metabolic signature in male mice at late adulthood	9
Exposure to the Organophosphate Pesticide Fenitrothion Directly Induced Defects in Mouse Embryonic External Genitalia	9
Mast cells are key mediators in the pulmonary inflammatory response to formaldehyde exposure	8
A mixture parameterized biologically based dosimetry model to predict body burdens of polycyclic aromatic hydrocarbons in developmental zebrafish toxicity assays	8
Pulmonary immune response regulation, genotoxicity, and metabolic reprogramming by menthol- and tobacco-flavored e-cigarette exposures in mice	8
A computational framework to in silico screen for drug-induced hepatocellular toxicity	8
Disposition of glycolic acid into the embryo following oral administration of ethylene glycol during placentation in the rat and rabbit	8
Developmental immunotoxicity study of tris(chloropropyl) phosphate in Hsd:Sprague Dawley SD rats exposed through dosed feed	8

An open-source interactive physiologically based pharmacokinetic model of tylosin in broiler chickens and laying hens	8
A transcriptomic biomarker predictive of cell proliferation for use in adverse outcome pathway-informed testing and assessment	8
Incorporating Metabolic Competence into High-Throughput Profiling Assays	8
An environmentally relevant mixture of per- and polyfluoroalkyl substances (PFAS) impacts proliferation, steroid hormone synthesis, and gene transcription in primary human granulosa cells	8
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats	8
Exposure to quasi-ultrafine particulate matter accelerates memory impairment and Alzheimer’s disease-like neuropathology in the AppNL-G-F knock-in mouse model	8
Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model	8
Developmental PFOS exposure alters lung inflammation and barrier integrity in juvenile mice	8
Corrigendum to: Children with Amalgam Dental Restorations Have Significantly Elevated Blood and Urine Mercury Levels	8
Is statistical re-evaluation of hemolymphoreticular neoplasms from aspartame studies valid?	7
Peripubertal exposure to oxyfluorfen, a diphenyl herbicide, delays pubertal development in the male rat by antagonizing androgen receptor activity	7
Pulmonary and neurological health effects associated with exposure to representative composite manufacturing emissions and corresponding alterations in circulating metabolite profiles	7
A pragmatic framework for the application of new approach methodologies in one health toxicological risk assessment	7
Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development inXenopus laevisUsing Iopanoic Acid	7
Naturally occurring autoimmune disease in (NZB × NZW) F1 mice is correlated with suppression of MZ B-cell development due to aberrant B-cell receptor (BCR) signaling, which is exacerbated by exposure	7
The aryl hydrocarbon receptor differentially modulates the expression profile of antibody isotypes in a human B-cell line	7
The imprinted geneZac1regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease	7
Maternal PBDE exposure disrupts gut microbiome and promotes hepatic proinflammatory signaling in humanized PXR-transgenic mouse offspring over time	7
Impact of artificial sunlight aging on the respiratory effects of polyethylene terephthalate microplastics through degradation-mediated terephthalic acid release in male mice	7
An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability	7
Comparative Genotoxicity and Mutagenicity of Cigarette, Cigarillo, and Shisha Tobacco Products in Epithelial and Cardiac Cells	7
Arsenic Induces GSK3β-Dependent p-Tau, Neuronal Apoptosis, and Cognitive Impairment via an Interdependent Hippocampal ERα and IL-1/IL-1R1 Mechanism in Female Rats	7
Long-term exposure to silica nanoparticles induces cardiac hypertrophy through the pyroptosis pathway	7
Impact of Neonatal Activation of Nuclear Receptor CAR (Nr1i3) on Cyp2 Gene Expression in Adult Mouse Liver	7
A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets	7
Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors	7
Considering developmental neurotoxicityin vitrodata for human health risk assessment using physiologically-based kinetic modeling: deltamethrin case study	7
Evaluation of the Uptake, Metabolism, and Secretion of Toxicants by Zebrafish Larvae	7
Alternative Flavored Inhalable Products—A New Respiratory Hazard?	7
DNA Damage and Repair and Epigenetic Modification in the Role of Oxoguanine Glycosylase 1 in Brain Development	7
Profiling the cytotoxic effects of naled and other pesticides in primary human placental cytotrophoblasts	7
In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array	7
Immunotoxicity of N-butylbenzenesulfonamide: impacts on immune function in adult mice and developmentally exposed rats	7
Dioxin Disrupts Thyroid Hormone and Glucocorticoid Induction of klf9, a Master Regulator of Frog Metamorphosis	6
Characterization of an Anti-CD70 Half-Life Extended Bispecific T-Cell Engager (HLE-BiTE) and Associated On-Target Toxicity in Cynomolgus Monkeys	6
Myclobutanil-mediated alteration of liver-gut FXR signaling in mice	6
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies	6
Synthetic Amorphous Silica Nanoparticles Promote Human Dendritic Cell Maturation and CD4+ T-Lymphocyte Activation	6
Evaluation of in vitro rat and human airway epithelial models for acute inhalation toxicity testing	6
Targeted Intracellular Demethylation of Methylmercury Enhances Elimination Kinetics and Reduces Developmental Toxicity in TransgenicDrosophila	6
Evidence evaluated by European Food Safety Authority does not support lowering the temporary tolerable daily intake for bisphenol A	6
Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities	6
The dose disrupts the pathway: application of Paracelsus principle to mechanistic toxicology	6
Increased sensitivity to chemically induced colitis in mice harboring a DNA-binding deficient aryl hydrocarbon receptor	6
Preclinical Toxicological Assessment of A Novel siRNA, SLN360, Targeting Elevated Lipoprotein (a) in Cardiovascular Disease	6
Reproductive and developmental toxicity following exposure to organophosphate ester flame retardants and plasticizers, triphenyl phosphate and isopropylated phenyl phosphate, in Sprague Dawley rats	6
Public health evaluation of PFAS exposures and breastfeeding: a systematic literature review	6
Emissions from plastic incineration induce inflammation, oxidative stress, and impaired bioenergetics in primary human respiratory epithelial cells	6
Arsenic causes distinct gene expression changes in macrophages polarizedin vitrowith either interferon-γ or interleukin-4	6
Corrigendum to: Polychlorinated Biphenyl–Induced Reduction of Dopamine Transporter Expression as a Precursor to Parkinson's Disease–Associated Dopamine Toxicity	6
Exploring the Influence of Experimental Design on Toxicity Outcomes in Zebrafish Embryo Tests	6
Perfluorooctane sulfonate exposure and alcohol-associated liver disease severity in a mouse chronic-binge ethanol feeding model	6
Excretion of polybrominated diphenyl ethers and AhR activation in breastmilk among firefighters	6
Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated in mouse and cynomolgus monkey toxicology studies	6
Single-cell insights into mouse testicular toxicity under peripubertal exposure to di(2-ethylhexyl) phthalate	6
Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases	6
Profiling mechanisms that drive acute oral toxicity in mammals and its prediction via machine learning	6
Comparing the Predictivity of Human Placental Gene, microRNA, and CpG Methylation Signatures in Relation to Perinatal Outcomes	6
Thank you, ToxSci 2023 reviewers	6
CardioMotion: identification of functional and structural cardiotoxic liabilities in small molecules through brightfield kinetic imaging	6
Increased Renal Expression of Complement Components in Patients With Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination	6
Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways	6
Cadmium exposure and osteoporosis: epidemiological evidence and mechanisms	5
Multi-Omics Strategies for Investigating the Microbiome in Toxicology Research	5
Fetal and neonatal dioxin exposure causes sex-specific metabolic alterations in mice	5
Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice	5
Per- and polyfluoroalkyl substances (PFAS) in mixtures show additive effects on transcriptomic points of departure in human liver spheroids	5
An in vitro and machine learning framework for quantifying serum albumin binding of per- and polyfluoroalkyl substances	5
Retraction: Research Article Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood-Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice	5
Human-relevant exposure to di-n-butyl phthalate tampers with the ovarian insulin-like growth factor 1 system and disrupts folliculogenesis in young adult mice	5
In Memoriam: Donald J. Reed (1930–2022)	5
Environmental exposome meets muscle wasting: unraveling the VOC-sarcopenia nexus through urinary metabolomics, inflammatory mediation, and network pharmacology in the NHANES cohort	5
Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated With Chemical Alterations ofIn VitroNeural Network Formation	5
Nicotinamide mononucleotide ameliorates impaired testicular spermatogenesis in uranium-exposed mice by modulating glycolytic pathways	5
Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with DESI mass spectrometry imaging	5
Evaluation of phenotypic and behavioral toxicity of micro- and nano-plastic polystyrene particles in larval zebrafish (Danio rerio)	5
Effects of PFAS on human liver transporters: implications for health outcomes	5
Threshold for increased liver weight is protective of other effects in Peromyscus exposed to PFNA	5
Validation of Risk-Stratification Method for the Chronic Atrioventricular Block Cynomolgus Monkey Model and Its Mechanistic Interpretation Using 6 Drugs With Pharmacologically Distinct Profile	5
Ferrostatin-1 mitigates cellular damage in a ferroptosis-like environment in Caenorhabditis elegans	5
Metabolic reprograming and increased inflammation by cadmium exposure following early-life respiratory syncytial virus infection: the involvement of protein S-palmitoylation	5
Developmental exposure to pesticides that disrupt retinoic acid signaling causes persistent retinoid and behavioral dysfunction in zebrafish	5
Toxicity of waterpipe tobacco smoking: the role of flavors, sweeteners, humectants, and charcoal	5
Gallic acid relieved bortezomib-induced peripheral neurotoxicity by restoring Schwann cell lysosomal activity	5
Exposure to phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice	5
An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol, and Penicillin	5
LncRNA HOTAIRM1 Involved in Nano NiO-Induced Pulmonary Fibrosis via Regulating PRKCB DNA Methylation-Mediated JNK/c-Jun Pathway	5
TCDD alters essential transcriptional regulators of osteogenic differentiation in multipotent mesenchymal stem cells	5
Development and safety of investigational and approved drugs targeting the RAS function regulation in RAS mutant cancers	5
CoQ10 Promotes Resolution of Necrosis and Liver Regeneration After Acetaminophen-Induced Liver Injury	5
Effects of dopamine agonists on the estradiol-induced prolactin surge in ovariectomized female Wistar Han rats	5
In vitro seizure risk assessment using a microelectrode array and comparison with an in vivo rat study	5
Early Drug-Induced Liver Injury Risk Screening: “Free,” as Good as It Gets	4
Associations Between Residential Exposure to Volatile Organic Compounds and Liver Injury Markers	4
The Analgesic Dipyrone Affects Pregnancy Outcomes and Endocrine-Sensitive Endpoints in Female and Male Offspring Rats	4