Journal of Biochemical and Molecular Toxicology

Article	Citations
Imbalanced GSH/ROS and sequential cell death	118
Enriched cancer stem cells, dense stroma, and cold immunity: Interrelated events in pancreatic cancer	64
The current knowledge concerning solid cancer and therapy	64
Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF‐7 human breast cancer cell line	59
Effects of heavy metals on reproduction owing to infertility	52
Chlorogenic acid induces 4T1 breast cancer tumor's apoptosis via p53, Bax, Bcl‐2, and caspase‐3 signaling pathways in BALB/c mice	39
Ferroptosis: A potential therapeutic target for neurodegenerative diseases	36
LncRNA Snhg8 attenuates microglial inflammation response and blood–brain barrier damage in ischemic stroke through regulating miR‐425‐5p mediated SIRT1/NF‐κB signaling	36
Rosmarinic acid attenuates chromium‐induced hepatic and renal oxidative damage and DNA damage in rats	35
Rutin ameliorates copper sulfate‐induced brain damage via antioxidative and anti‐inflammatory activities in rats	33
Synthesis, molecular docking, DFT study, and in vitro antimicrobial activity of some 4‐(biphenyl‐4‐yl)‐1,4‐dihydropyridine and 4‐(biphenyl‐4‐yl)pyridine derivatives	30
Discovery of novel pyrazole derivatives as a potent anti‐inflammatory agent in RAW264.7 cells via inhibition of NF‐ĸB for possible benefit against SARS‐CoV‐2	30
Cisplatin‐conjugated gold nanoparticles‐based drug delivery system for targeting hepatic tumors	29
Nephroprotective effect of umbelliferone against cisplatin‐induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO‐3, and NF‐kB‐p65 signaling pathways	28
The effects of mesenchymal stem cell mitochondrial transplantation on doxorubicin‐mediated nephrotoxicity in rats	28
Evaluation of the hepatoprotective effects of curcumin and nanocurcumin against paraquat‐induced liver injury in rats: Modulation of oxidative stress and Nrf2 pathway	27
Neuroprotective role of chrysin‐loaded poly(lactic‐co‐glycolic acid) nanoparticle against kindling‐induced epilepsy through Nrf2/ARE/HO‐1 pathway	27
Biologically active phthalocyanine metal complexes: Preparation, evaluation of α‐glycosidase and anticholinesterase enzyme inhibition activities, and molecular docking studies	26
Modulation of antioxidant enzymes, SIRT1 and NF‐κB by resveratrol and nicotinamide in alcohol‐aflatoxin B1‐induced hepatocellular carcinoma	26
Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer	25
From nature to therapy: Luteolin's potential as an immune system modulator in inflammatory disorders	24
Exosomal miR‐512‐3p derived from mesenchymal stem cells inhibits oxidized low‐density lipoprotein‐induced vascular endothelial cells dysfunction via regulating Keap1	24
LncRNA PVT1 exacerbates the inflammation and cell‐barrier injury during asthma by regulating miR‐149	24
Ferulic acid alleviates lipopolysaccharide‐induced acute lung injury through inhibiting TLR4/NF‐κB signaling pathway	24
Thymoquinone attenuates doxorubicin‐cardiotoxicity in rats	24

Neuroprotective potential of cinnamon and its metabolites in Parkinson's disease: Mechanistic insights, limitations, and novel therapeutic opportunities	24
Recent developments in the methods of quantitative analysis of microcystins	24
A review on the physiological and pathophysiological role of endothelial glycocalyx	23
The protective effect of natural compounds against rotenone‐induced neurotoxicity	23
Cinnamaldehyde and hesperetin attenuate TNBS‐induced ulcerative colitis in rats through modulation of the JAk2/STAT3/SOCS3 pathway	23
Neuroprotective role of gallic acid in aflatoxin B1‐induced behavioral abnormalities in rats	23
A novel role of the miR‐152‐3p/ERRFI1/STAT3 pathway modulates the apoptosis and inflammatory response after acute kidney injury	23
Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo	23
Silybin phytosome attenuates cerebral ischemia‐reperfusion injury in rats by suppressing oxidative stress and reducing inflammatory response: In vivo and in silico approaches	23
The ameliorative effect ofN‐acetylcysteine against penconazole induced neurodegenerative and neuroinflammatory disorders in rats	22
Loperamide potentiates doxorubicin sensitivity in triple‐negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl‐2: In vitro and molecular docking study	22
Effect of hesperidin on fluoride‐induced neurobehavioral and biochemical changes in rats	22
Coaction of hepatic thioredoxin and glutathione systems in iron overload‐induced oxidative stress	22
JAK1/STAT3 regulatory effect of β‐caryophyllene on MG‐63 osteosarcoma cells via ROS‐induced apoptotic mitochondrial pathway by DNA fragmentation	22
Curcumin induced apoptosis is mediated through oxidative stress in mutated p53 and wild type p53 colon adenocarcinoma cell lines	21
Methyl benzoate derivatives: in vitro Paraoxonase 1 inhibition and in silico studies	20
The modulation of SIRT1 and SIRT3 by natural compounds as a therapeutic target in doxorubicin‐induced cardiotoxicity: A review	20
ROS accumulation contributes to abamectin‐induced apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway in TM3 Leydig cells	20
The selective toxicity of superparamagnetic iron oxide nanoparticles (SPIONs) on oral squamous cell carcinoma (OSCC) by targeting their mitochondria	20
Antiosteoporotic effect of hesperidin against ovariectomy‐induced osteoporosis in rats via reduction of oxidative stress and inflammation	20
Effect of m6A methyltransferase METTL3 ‐mediated MALAT1/E2F1/AGR2 axis on adriamycin resistance in breast cancer	20
Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride‐induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling	19
Proanthocyanidin alleviates doxorubicin‐induced cardiac injury by inhibiting NF‐kB pathway and modulating oxidative stress, cell cycle, and fibrogenesis	19
Platycodin D suppresses cisplatin‐induced cytotoxicity by suppressing ROS‐mediated oxidative damage, apoptosis, and inflammation in HEK‐293 cells	19
Ginsenoside Rh2 impedes proliferation and migration and induces apoptosis by regulating NF‐κB, MAPK, and PI3K/Akt/mTOR signaling pathways in osteosarcoma cells	19
Zinc deficient diet increases the toxicity of bisphenol A in rat testis	19
Rutin restrains the growth and metastasis of mouse breast cancer cells by regulating the microRNA‐129‐1‐3p‐mediated calcium signaling pathway	19
Evaluation of in vitro inhibitory effects of some natural compounds on tyrosinase activity and molecular docking study: Antimelanogenesis potential	19
Carbendazim toxicity in different cell lines and mammalian tissues	19
Investigation of oxidant/antioxidant and anti‐inflammatory effects of apigenin on apoptosis in sepsis‐induced rat lung	19
Modulating NF‐κB, MAPK, and PI3K/AKT signaling by ergothioneine attenuates iron overload‐induced hepatocellular injury in rats	19
Natural compounds against cytotoxic drug‐induced cardiotoxicity: A review on the involvement of PI3K/Akt signaling pathway	19
Piperlongumine attenuates oxidative stress, inflammatory, and apoptosis through modulating the GLUT‐2/4 and AKT signaling pathway in streptozotocin‐induced diabetic rats	18
In vitro comparative cytotoxic assessment of pristine and carboxylic functionalized multiwalled carbon nanotubes on LN18 cells	18
Selenium nanoparticles and quercetin suppress thioacetamide‐induced hepatocellular carcinoma in rats: Attenuation of inflammation involvement	18
Biological evaluation and in silico study of benzohydrazide derivatives as paraoxonase 1 inhibitors	18
Effects of metformin and pioglitazone combination on apoptosis and AMPK/mTOR signaling pathway in human anaplastic thyroid cancer cells	17
Understanding the complicated relationship between antioxidants and carcinogenesis	17
Protective effect of carnosic acid on acrylamide‐induced liver toxicity in rats: Mechanistic approach over Nrf2‐Keap1 pathway	17
Protective effects of natural compounds against oxidative stress in ischemic diseases and cancers via activating the Nrf2 signaling pathway: A mini review	17
Cirsilineol attenuates LPS‐induced inflammation in both in vivo and in vitro models via inhibiting TLR‐4/NFkB/IKK signaling pathway	17
The deleterious effect of stress‐induced depression on rat liver: Protective role of resveratrol and dimethyl fumarate via inhibiting the MAPK/ERK/JNK pathway	17
Visnagin prevents isoproterenol‐induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats	17
Versatile role of sirtuins in metabolic disorders: From modulation of mitochondrial function to therapeutic interventions	17
Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives	16
Inhibition of NF‐κB is required for oleanolic acid to downregulate PD‐L1 by promoting DNA demethylation in gastric cancer cells	16
Advanced glycation end products and their adverse effects: The role of autophagy	16
Upregulation of lncRNA DARS‐AS1 accelerates tumor malignancy in cervical cancer by activating cGMP‐PKG pathway	16
Metformin and silymarin afford protection in cyclosporine A induced hepatorenal toxicity in rat by modulating redox status and inflammation	16
Zingerone suppresses cell proliferation via inducing cellular apoptosis and inhibition of the PI3K/AKT/mTOR signaling pathway in human prostate cancer PC‐3 cells	16

Bisphenol A exposure induces neurobehavioral deficits and neurodegeneration through induction of oxidative stress and activated caspase‐3 expression in zebrafish brain	16
In silico study, synthesis, and evaluation of the antimalarial activity of hybrid dimethoxy pyrazole 1,3,5‐triazine derivatives	16
SIRT1‐mediated amelioration of oxidative stress in kidney of alcohol‐aflatoxin‐B1‐induced hepatocellular carcinoma by resveratrol is catalase dependent and GPx independent	16
Crocin treatment promotes the oxidative stress and apoptosis in human thyroid cancer cells FTC‐133 through the inhibition of STAT/JAK signaling pathway	16
MicroRNAs and gene regulation in breast cancer	15
Homocysteine induced a calcium‐mediated disruption of mitochondrial function and dynamics in endothelial cells	15
The effect of ellagic acid on spinal cord and sciatica function in a mice model of multiple sclerosis	15
Decision making for promising quinoline‐based anticancer agents through combined methodology	15
Long noncoding RNA CRNDE functions as a diagnostic and prognostic biomarker in osteosarcoma, as well as promotes its progression via inhibition of miR‐335‐3p	15
Anti‐apoptotic effect of vinpocetine on cisplatin‐induced hepatotoxicity in mice: The role of Annexin‐V, Caspase‐3, and Bax	15
N‐arachidonoyl dopamine inhibits epithelial–mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol	15
Apigenin ameliorates oxidative stress and mitochondrial damage induced by multiwall carbon nanotubes in rat kidney mitochondria	15
Ethanol exacerbates manganese‐induced oxidative/nitrosative stress, pro‐inflammatory cytokines, nuclear factor‐κB activation, and apoptosis induction in rat cerebellar cortex	14
LINC00511 facilitates Temozolomide resistance of glioblastoma cells via sponging miR‐126‐5p and activating Wnt/β‐catenin signaling	14
Effects of quercetin on apoptosis and extracellular matrix degradation of chondrocytes induced by oxidative stress‐mediated pyroptosis	14
Citronellal ameliorates doxorubicin‐induced hepatotoxicity via antioxidative stress, antiapoptosis, and proangiogenesis in rats	14
ZNF667‐AS1, a positively regulating MEGF10, inhibits the progression of uveal melanoma by modulating cellular aggressiveness	14
Selective anticancer activity of superparamagnetic iron oxide nanoparticles (SPIONs) against oral tongue cancer using in vitro methods: The key role of oxidative stress on cancerous mitochondria	14
Mangiferin prevents the impairment of mitochondrial dynamics and an increase in oxidative stress caused by excessive fluoride in SH‐SY5Y cells	14
Thymoquinone has a neuroprotective effect against inflammation, oxidative stress, and endoplasmic reticulum stress in the brain cortex, medulla, and hippocampus due to doxorubicin	14
Perfluorooctanoic acid activates the unfolded protein response in pancreatic acinar cells	14
Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO‐1/NF‐κB signaling pathway	14
SNHG5 protects chondrocytes in interleukin‐1β‐stimulated osteoarthritis via regulating miR‐181a‐5p/TGFBR3 axis	14
Requirements for successful mitochondrial transplantation	14
Cabazitaxel exhibits more favorable molecular changes compared to other taxanes in androgen‐independent prostate cancer cells	14
Effects of rhaponticin on retinal oxidative stress and inflammation in diabetes through NRF2/HO‐1/NF‐κB signalling	14
Potential thiosemicarbazone‐based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking calculations	14
Ginsenoside‐Rg1 attenuates sepsis‐induced cardiac dysfunction by modulating mitochondrial damage via the P2X7 receptor‐mediated Akt/GSK‐3β signaling pathway	14
Ameliorative role of curcumin on copper oxide nanoparticles‐mediated renal toxicity in rats: An investigation of molecular mechanisms	13
MiRNA‐Wnt signaling regulatory network in colorectal cancer	13
The potential implications of estrogenic and antioxidant‐dependent activities of high doses of methyl paraben on MCF7 breast cancer cells	13
Atorvastatin attenuates pulmonary fibrosis in mice and human lung fibroblasts, by the regulation of myofibroblast differentiation and apoptosis	13
RIP3/MLKL pathway‐regulated necroptosis: A new mechanism of paclitaxel‐induced peripheral neuropathy	13
Genetic mutations of APOEε4 carriers in cardiovascular patients lead to the development of insulin resistance and risk of Alzheimer's disease	13
Purpurin binding interacts with LHPP protein that inhibits PI3K/AKT phosphorylation and induces apoptosis in colon cancer cells HCT‐116	13
Sesquiterpenoid bilobalide inhibits gastric carcinoma cell growth and induces apoptosis both in vitro and in vivo models	13
Proanthocyanidins attenuate the high glucose‐induced damage of retinal pigment epithelial cells by attenuating oxidative stress and inhibiting activation of the NLRP3 inflammasome	13
Reversal of cisplatin resistance by neferine/isoliensinine and their combinatorial regimens with cisplatin‐induced apoptosis in cisplatin‐resistant colon cancer stem cells (CSCs)	13
Protective roles and mechanisms of rosmarinic acid in cyclophosphamide‐induced premature ovarian failure	13
The protective effect of vitamin U on valproic acid‐induced lung toxicity in rats via amelioration of oxidative stress	13
Silencing of circCDC14A prevents cerebral ischemia‐reperfusion injury via miR‐23a‐3p/CXCL12 axis	13
Rutin treats myocardial damage caused by pirarubicin via regulating miR‐22‐5p‐regulated RAP1/ERK signaling pathway	13
A review on extracorporeal membrane oxygenation and kidney injury	12
Susceptibility to COVID‐19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants	12
Epoxyazadiradione induced apoptosis/anoikis in triple‐negative breast cancer cells, MDA‐MB‐231, by modulating diverse cellular effects	12
6‐Gingerol suppresses tumor cell metastasis by increasing YAPser127 phosphorylation in renal cell carcinoma	12
Ginsenoside Rg3 attenuates cisplatin‐induced kidney injury through inhibition of apoptosis and autophagy‐inhibited NLRP3	12
Environmental exposures and the etiopathogenesis of Alzheimer's disease: The potential role of BACE1 as a critical neurotoxic target	12
Spiraeoside protects human cardiomyocytes against high glucose‐induced injury, oxidative stress, and apoptosis by activation of PI3K/Akt/Nrf2 pathway	12
Beneficial effects of (−)‐epigallocatechin‐3‐O‐gallate on diabetic peripheral neuropathy in the rat model	12
Sinapic acid safeguards cardiac mitochondria from damage in isoproterenol‐induced myocardial infarcted rats	12
Benzimidazolium salts bearing the trifluoromethyl group as organofluorine compounds: Synthesis, characterization, crystal structure, in silico study, and inhibitory profiles against acetylcholinestera	12
Quercetin attenuates cyclophosphamide induced‐immunosuppressive indoleamine 2,3‐dioxygenase in the hippocampus and cerebral cortex of male Wister rats	12
[6]‐Gingerol impedes 7,12‐dimethylbenz(a)anthracene‐induced inflammation and cell proliferation‐associated hamster buccal pouch carcinogenesis through modulating Nrf2 signaling events	12
The potential toxic effects of magnesium oxide nanoparticles and valproate on liver tissue	12
Propofol protects cardiomyocytes from hypoxia/reoxygenation injury via regulating MALAT1/miR‐206/ATG3 axis	12
Protective effect of astaxanthin on experimental ovarian damage in rats	12
Shifting of cell cycle arrest from the S‐phase to G2/M phase and downregulation of EGFR expression by phytochemical combinations in HeLa cervical cancer cells	12
Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ‐induced diabetic rats	12
Strategic targeting of non‐small‐cell lung cancer utilizing genetic material‐based delivery platforms of nanotechnology	12
Boldine treatment protects acetaminophen‐induced liver inflammation and acute hepatic necrosis in mice	12
Preconditioning the rat heart with 5‐azacytidine attenuates myocardial ischemia/reperfusion injury via PI3K/GSK3β and mitochondrial KATP signaling axis	12
Eriocitrin, a dietary flavonoid suppressed cell proliferation, induced apoptosis through modulation of JAK2/STAT3 and JNK/p38 MAPKs signaling pathway in MCF‐7 cells	12
Novel amino acid Schiff base Zn(II) complexes as new therapeutic approaches in diabetes and Alzheimer's disease: Synthesis, characterization, biological evaluation, and molecular docking studies	12
Daphnetin exerts an anticancer effect by attenuating the pro‐inflammatory cytokines	12
Protective effect of panaxydol against repeated administration of aristolochic acid on renal function and lipid peroxidation products via activating Keap1‐Nrf2/ARE pathway in rat kidney	12
microRNA‐186 alleviates oxygen‐glucose deprivation/reoxygenation‐induced injury by directly targeting hypoxia‐inducible factor‐1α	12
Tomentosin inhibits cell proliferation and induces apoptosis in MOLT‐4 leukemia cancer cells through the inhibition of mTOR/PI3K/Akt signaling pathway	12
Vitexin prevents Aβ proteotoxicity in transgenic Caenorhabditis elegans model of Alzheimer's disease by modulating unfolded protein response	12
Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β‐catenin signaling pathways	12
Curcumin alleviates acute kidney injury in a dry‐heat environment by reducing oxidative stress and inflammation in a rat model	11
Protective effect of valsartan against doxorubicin‐induced cardiotoxicity: Histopathology and metabolomics in vivo study	11
Developmental toxicity, antioxidant, and marker enzyme assessment of swertiamarin in zebrafish (Danio rerio)	11
Exposure to environmental pollutant bisphenol A causes oxidative damage and lipid accumulation in Zebrafish larvae: Protective role of WL15 peptide derived from cysteine and glycine‐rich protein 2	11
Protective effect of naringin against oxaliplatin‐induced peripheral neuropathy in rats: A behavioral and molecular study	11
miR‐141‐5p suppresses vascular smooth muscle cell inflammation, proliferation, and migration via inhibiting the HMGB1/NF‐κB pathway	11
Scutebarbatine A induces cytotoxicity in hepatocellular carcinoma via activation of the MAPK and ER stress signaling pathways	11
Downregulation of long noncoding RNA SNHG7 protects against inflammation and apoptosis in Parkinson's disease model by targeting the miR‐425‐5p/TRAF5/NF‐κB axis	11
Neuroprotective effect of alpha‐pinene is mediated by suppression of the TNF‐α/NF‐κB pathway in Alzheimer's disease rat model	11
Anticancer activity of Vicenin‐2 against 7,12 dimethylbenz[a]anthracene‐induced buccal pouch carcinoma in hamsters	11

Association between SLCO1A2 genetic variation and methotrexate toxicity in human rheumatoid arthritis treatment	11
Scutellarein induces apoptosis and inhibits proliferation, migration, and invasion in ovarian cancer via inhibition of EZH2/FOXO1 signaling	11
Arbutin attenuates ethanol‐induced acute hepatic injury by the modulation of oxidative stress and Nrf‐2/HO‐1 signaling pathway	11
Attenuation effect of polydeoxyribonucleotide on inflammatory cytokines and apoptotic factors induced by particulate matter (PM10) damage in human bronchial cells	11
Natural quinones induce ROS‐mediated apoptosis and inhibit cell migration in PANC‐1 human pancreatic cancer cell line	11
Upregulated lnc‐HZ02 and miR‐hz02 inhibited migration and invasion by downregulating the FAK/SRC/PI3K/AKT pathway in BPDE‐treated trophoblast cells	11
Embelin: A novel XIAP inhibitor for the prevention and treatment of chronic diseases	11
Capsaicin inhibits cell proliferation by enhancing oxidative stress and apoptosis through SIRT1/NOX4 signaling pathways in HepG2 and HL‐7702 cells	11
Myrtenol alleviates oxidative stress and inflammation in diabetic pregnant rats via TLR4/MyD88/NF‐κB signaling pathway	11
Novel insights into the potential mechanisms underlying carbendazim‐induced hepatorenal toxicity in rats	11
Rosmarinic acid relieves cisplatin‐induced ovary toxicity in female mice via suppression of oxidative stress and inflammation	11
Thymol ameliorates 5‐fluorouracil‐induced intestinal mucositis: Evidence of down‐regulatory effect on TGF‐β/MAPK pathways through NF‐κB	11
Ameliorative effect of betanin on experimental cisplatin‐induced liver injury; the novel impact of miRNA‐34a on the SIRT1/PGC‐1α signaling pathway	10
Protective role of zinc in liver damage in experimental diabetes demonstrated via different biochemical parameters	10
Exosomes derived from ADSCs containing miR‐378 promotes wound healing by targeting caspase‐3	10
Sirtuin‐3 activation by honokiol restores mitochondrial dysfunction in the hippocampus of the hepatic encephalopathy rat model of ammonia neurotoxicity	10
Cdc42 promotes thyroid cancer cell proliferation and migration and tumor‐associated macrophage polarization through the PTEN/AKT pathway	10
miR‐217 alleviates high‐glucose‐induced vascular smooth muscle cell dysfunction via regulating ROCK1	10
Surface modifications affect iron oxide nanoparticles' biodistribution after multiple‐dose administration in rats	10
Protective effects of 6‐gingerol on 6‐hydroxydopamine‐induced apoptosis in PC12 cells through modulation of SAPK/JNK and survivin activation	10
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline‐induced myocardial infarction via MIAT/miR‐200a/Nrf2/TXINP pathway	10
Cordyceps acid alleviates lung cancer in nude mice	10
S‐allyl cysteine, an active ingredient of garlic, attenuates acute liver dysfunction induced by lipopolysaccharide/d‐galactosamine in mouse: Underlying mechanisms	10
Antitumor activity of sitagliptin and vitamin B12 on Ehrlich ascites carcinoma solid tumor in mice	10
Cefepime and diclofenac sodium combined treatment‐potentiated multiple organ injury: Role of oxidative damage and disrupted lipid metabolism	10
Proteomics analysis of meclofenamic acid‐treated small cell lung carcinoma cells revealed changes in cellular energy metabolism for cancer cell survival	10
miR‐20a‐5p promotes pulmonary artery smooth muscle cell proliferation and migration by targeting ABCA1	10
NF‐κB‐upregulated miR‐155‐5p promotes hepatocyte mitochondrial dysfunction to accelerate the development of nonalcoholic fatty liver disease through downregulation of STC1	10
Celecoxib decreases mitochondrial complex IV activity and induces oxidative stress in isolated rat heart mitochondria: An analysis for its cardiotoxic adverse effect	10
The protective effect of resveratrol on diazinon‐induced oxidative stress and glucose hemostasis disorder in rats' liver	10
A synthetic coumarin derivative (4‐flourophenylacetamide‐acetyl coumarin) impedes cell cycle at G0/G1 stage, induces apoptosis, and inhibits metastasis via ROS‐mediated p53 and AKT signaling pathways	10
Pinocembrin attenuates benzo(a)pyrene‐induced CYP1A1 expression through multiple pathways: An in vitro and in vivo study	10
Deregulation of hepatic lipid metabolism associated with insulin resistance in rats subjected to chronic monocrotophos exposure	10
TMEM88 exhibits an antiproliferative and anti‐invasive effect in bladder cancer by downregulating Wnt/β‐catenin signaling	10
Rhodojaponin II inhibits TNF‐α‐induced inflammatory cytokine secretion in MH7A human rheumatoid arthritis fibroblast‐like synoviocytes	10
Downregulating lncRNA PRNCR1 ameliorates LPS‐induced pulmonary vascular endothelial cell injury by modulating miR‐330‐5p/TLR4 axis	10
Eugenol–piperine loaded polyhydroxy butyrate/polyethylene glycol nanocomposite‐induced apoptosis and cell death in nasopharyngeal cancer (C666‐1) cells through the inhibition of the PI3K/AKT/mTOR sign	10
Baicalin regulates mRNA expression of VEGF‐c, Ang‐1/Tie2, TGF‐β and Smad2/3 to inhibit wound healing in streptozotocin‐induced diabetic foot ulcer rats	10
Ferutinin: A phytoestrogen from ferula and its anticancer, antioxidant, and toxicity properties	10
Betulin ameliorates 7,12‐dimethylbenz(a)anthracene‐induced rat mammary cancer by modulating MAPK and AhR/Nrf‐2 signaling pathway	9
Suppression of reactive oxygen species in endothelial cells by an antagonist of growth hormone‐releasing hormone	9
Disturbed mitochondrial redox state and tissue energy charge in cholestasis	9
Antioxidant for treatment of diabetic complications: A meta‐analysis and systematic review	9
Syringic acid, a novel thyroid hormone receptor‐β agonist, ameliorates propylthiouracil‐induced thyroid toxicity in rats	9
Renoprotective potential of myo‐inositol on diabetic kidney disease: Focus on the role of the PINK1/Parkin pathway and mitophagy receptors	9
The effects of thymoquinone and quercetin on the toxicity of acrylamide in rat glioma cells	9
Sodium houttuyfonate attenuates neurological defects after traumatic brain injury in mice via inhibiting NLRP3 inflammasomes	9
Susceptibility of male reproductive system to bisphenol A, an endocrine disruptor: Updates from epidemiological and experimental evidence	9
Alpha‐lipoic acid prevents brain injury in rats administered with valproic acid	9
Hesperidin alleviates bupivacaine anesthesia‐induced neurotoxicity in SH‐SY5Y cells by regulating apoptosis and oxidative damage	9
Tanshinone II A improves the chemosensitivity of breast cancer cells to doxorubicin by inhibiting β‐catenin nuclear translocation	9
Betulinic acid abates N‐nitrosodimethylamine‐induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats	9
Preparation, DFT calculations, docking studies, antioxidant, and anticancer properties of new pyrazole and pyridine derivatives	9
Long noncoding RNA DARS‐AS1 regulates TP53 ubiquitination and affects ovarian cancer progression by modulation miR‐194‐5p/RBX1 axis	9
The advance anticancer role of polymeric core‐shell ZnO nanoparticles containing oxaliplatin in colorectal cancer	9
Low dose epigallocatechin‐3‐gallate revives doxorubicin responsiveness by a redox‐sensitive pathway in A549 lung adenocarcinoma cells	9
Epigallocatechin gallate and coenzyme Q10 attenuate cisplatin‐induced hepatotoxicity in rats via targeting mitochondrial stress and apoptosis	9
Vernodalin induces apoptosis through the activation of ROS/JNK pathway in human colon cancer cells	9
Cardiopreventive capacity of a novel (E)‐Nʹ‐(1‐(7‐methoxy‐2‐oxo‐2H‐chromen‐3‐yl) ethylidene)‐4‐methylbenzenesulfonohydrazide against isoproterenol‐induced myocardial infarction by moderating biochemic	9
Cerium oxide nanoparticles elicit antitumourigenic effect in experimental breast cancer induced by N‐methyl‐N‐nitrosourea and benzo(a)pyrene in female Wistar rats	9
The inhibitory mechanisms of losartan and vitamin D on amiodarone‐induced lung inflammation in rats: Role of mitogen‐activated protein kinases/activator protein‐1	9
Pinitol attenuates LPS‐induced pneumonia in experimental animals: Possible role via inhibition of the TLR‐4 and NF‐κB/IκBα signaling cascade pathway	8
Combined approaches for evaluation of xenoestrogen neural toxicity and thyroid dysfunction: Screening of oxido‐nitrosative markers, DNA fragmentation, and biogenic amine degradation	8
Nicotinamide attenuates cyclophosphamide‐induced hepatotoxicity in SD rats by reducing oxidative stress and apoptosis	8
Neferine attenuates doxorubicin‐induced fibrosis and hypertrophy in H9c2 cells	8
Sodium benzoate induces neurobehavioral deficits and brain oxido‐inflammatory stress in male Wistar rats: Ameliorative role of ascorbic acid	8
SOX4 induces drug resistance of colorectal cancer cells by downregulating CYLD through transcriptional activation of microRNA‐17	8
Cytotoxicity of metformin against HT29 colon cancer cells contributes to mitochondrial Sirt3 upregulation	8
Organophosphate‐pesticides induced survival mechanisms and APE1‐mediated Nrf2 regulation in non‐small‐cell lung cancer cells	8
Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR‐4/NF‐κB, and JAK1/STAT3 signaling in cyclophosphamide‐intoxicated rats	8
Synthesis, molecular docking, ADME study, and antimicrobial potency of piperazine based cinnamic acid bearing coumarin moieties as a DNA gyrase inhibitor	8
Catechin and epicatechin as an adjuvant in the therapy of hemostasis disorders induced by snake venoms	8
The potential mechanism underlying the hepatorenal toxicity induced by hymexazol in rats and the role of NF‐κB signaling pathway	8
Local anesthetic bupivacaine inhibits proliferation and metastasis of hepatocellular carcinoma cells via suppressing PI3K/Akt and MAPK signaling	8
Emetine exerts anticancer effects in U2OS human osteosarcoma cells via activation of p38 and inhibition of ERK, JNK, and β‐catenin signaling pathways	8
Overexpression of heat shock protein 70 enhanced mesenchymal stem cell treatment efficacy in phosgene‐induced acute lung injury	8
Deoxyshikonin inhibits cisplatin resistance of non–small‐cell lung cancer cells by repressing Akt‐mediated ABCB1 expression and function	8
SNHG10/miR‐141‐3p/WTAP axis promotes osteosarcoma proliferation and migration	8
Synergistic effect of anethole and doxorubicin alleviates cell proliferation, cell cycle arrest, and ER stress and promotes ROS‐mediated apoptosis in triple‐negative breast cancer cells	8
Decabromodiphenyl ether induces ROS‐mediated intestinal toxicity through the Keap1‐Nrf2 pathway	8
Marine bioactive compound dieckol induces apoptosis and inhibits the growth of human pancreatic cancer cells PANC‐1	8
4‐O‐methylascochlorin activates autophagy by activating AMPK and suppressing c‐Myc in glioblastoma	8
l‐Arginine prevents 4‐hydroxy‐2‐nonenal accumulation and depresses inflammation via inhibiting NF‐κB activation	8
Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta‐TC‐6 cells via the generation of intracellular reactive oxygen species and mitochondrial superox	8
Sulforaphene targets NLRP3 inflammasome to suppress M1 polarization of macrophages and inflammatory response in rheumatoid arthritis	8
Studies on male gonadal toxicity of bisphenol A in diabetic rats: An example of exacerbation effect	8
Linagliptin, the dipeptidyl peptidase‐4 enzyme inhibitor, lessens CHOP and GRP78 biomarkers levels in cisplatin‐induced neurobehavioral deficits: A possible restorative gateway	8
The effect of a bis‐structured Schiff base on apoptosis, cytotoxicity, and DNA damage of breast cancer cells	8
Faster lipid β‐oxidation rate by acetyl‐CoA carboxylase 2 inhibition alleviates high‐glucose‐induced insulin resistance via SIRT1/PGC‐1α in human podocytes	8
Involvement of NF‐κB/PI3K/AKT signaling pathway in the protective effect of prunetin against a diethylnitrosamine induced hepatocellular carcinogenesis in rats	8
Biochemical and histological alterations of doxorubicin‐induced neurotoxicity in rats: Protective role of luteolin	8
Antioxidative effects of silymarin on the reduction of liver complications of fingolimod in patients with relapsing–remitting multiple sclerosis: A clinical trial study	8
Citronellal alleviates doxorubicin‐induced cardiotoxicity by suppressing oxidative stress and apoptosis via Na+/H+ exchanger‐1 inhibition	8
Effect of fumonisin B1 on oxidative stress and gene expression alteration of nutrient transporters in porcine intestinal cells	8
Hesperetin ameliorates lipopolysaccharide‐induced acute lung injury via the miR‐410/SOX18 axis	8