OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Genomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The COVID-19 pandemic: a global health crisis	295
SARS-CoV-2, ACE2 expression, and systemic organ invasion	114
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project	58
Implementation of convolutional neural network approach for COVID-19 disease detection	32
Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch	28
Cell-free DNA and RNA—measurement and applications in clinical diagnostics with focus on metabolic disorders	27
Nrf2 signaling in heart failure: expression of Nrf2, Keap1, antioxidant, and detoxification genes in dilated or ischemic cardiomyopathy	26
Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD	20
Drivers of transcriptional variance in human intestinal epithelial organoids	20
Methylation of histone 4’s lysine 20: a critical analysis of the state of the field	18
Genomic and epigenomic active vitamin D responses in human colonic organoids	15
Can cilia provide an entry gateway for SARS-CoV-2 to human ciliated cells?	14
Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia	14
Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity	14
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study	14
Identification of a peripheral blood gene signature predicting aortic valve calcification	12
Probing metabolic memory in the hepatic response to fasting	12
mRatBN7.2: familiar and unfamiliar features of a new rat genome reference assembly	12
Frequency and management of medically actionable incidental findings from genome and exome sequencing data: a systematic review	12
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways	12
Characteristics of circular RNAs expression of peripheral blood mononuclear cells in humans with coronary artery disease	11
Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction	11
Progesterone-dependent and progesterone-independent modulation of luminal epithelial transcription to support pregnancy in cattle	11
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	11
Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise	11

eQTL variants in COL22A1 are associated with muscle injury in athletes	11
Time-course analysis of the effect of embedded metal on skeletal muscle gene expression	10
Gut microbiota of wild fish as reporters of compromised aquatic environments sleuthed through machine learning	10
Difference in potential DNA methylation impact on gene expression between fast- and slow-type myofibers	10
Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity	9
Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension	9
METTL3-mediated m6A modification promotes processing and maturation of pri-miRNA-19a to facilitate nasopharyngeal carcinoma cell proliferation and invasion	9
Assessing the impact of boldine on the gastrocnemius using multiomics profiling at 7 and 28 days post-complete spinal cord injury in young male mice	8
Platelet proteome dynamics in hibernating 13-lined ground squirrels	8
Human endogenous retroviruses: our genomic fossils and companions	8
Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats	8
Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion	8
Chronic jetlag-induced alterations in pancreatic diurnal gene expression	8
The adducin saga: pleiotropic genomic targets for precision medicine in human hypertension—vascular, renal, and cognitive diseases	7
Na⁺/Cl⁻ cotransporter 2 is not fish-specific and is widely found in amphibians, non-avian reptiles, and select mammals	7
Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling	7
Dynamic transcriptomic responses to divergent acute exercise stimuli in young adults	6
The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats	6
RNA sequencing indicates age-dependent shifts in the cardiac fibroblast transcriptome between fetal, neonatal, and adult developmental ages	6
Integrated analysis of transcriptome profiling of lncRNAs and mRNAs in livers of type 2 diabetes mellitus	6
Dysregulation of miR-21-associated miRNA regulatory networks by chronic ethanol consumption impairs liver regeneration	6
Dynamic alterations in yak (Bos grunniens) rumen microbiome in response to seasonal variations in diet	6
Liver transcriptome response to periparturient hormonal and metabolic changes depends on the postpartum occurrence of subacute ruminal acidosis in Holstein cows	6
Single-cell RNA sequencing of mouse left ventricle reveals cellular diversity and intercommunication	6
Muscle transcriptomic circuits linked to periarticular physiology in end-stage osteoarthritis	5
LncRNA CARMN inhibits cervical cancer cell growth via the miR-92a-3p/BTG2/Wnt/β-catenin axis	5
Integrative physiology of lysine metabolites	5
SARS-CoV-2 transgressing LncRNAs uncovers the known unknowns	5
Age-dependent transcriptional alterations in cardiac endothelial cells	5
MicroRNA cargo of extracellular vesicles released by skeletal muscle fibro-adipogenic progenitor cells is significantly altered with disuse atrophy and IL-1β deficiency	5
Echocardiography phenotyping in murine genetic reference population of BXD strains reveals significant QTLs associated with cardiac function and morphology	5
Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies	5
Shared aspects of mRNA expression associated with oocyte maturation failure in humans and rhesus monkeys indicating compromised oocyte quality	5
Circulating extracellular DNA is in association with continuous metabolic syndrome score in healthy adolescents	5