OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Genomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown	27
Investigative power of genomic informational field theory relative to genome-wide association studies for genotype-phenotype mapping	24
Identification of shared and disease-specific intratumoral microbiome-host gene associations in gastrointestinal tumors	20
Prolonged obesity alters males’ adipose profile: implications for disease?	20
Assessing the impact of boldine on the gastrocnemius using multiomics profiling at 7 and 28 days post-complete spinal cord injury in young male mice	19
Impact of stress phenotype, elevated temperature, and bacterin exposure on male Atlantic salmon (Salmo salar) growth, stress, and immune biomarker gene expression	19
Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia	18
Analysis of a genetic region affecting mouse body weight	18
Deciphering taxonomic and functional patterns of microbial communities associated with the tiger tail seahorse (Hippocampus comes)	17
The expression profile of 79 genes from 107 viruses revealed new insights into disease susceptibility in rats, mice, and muskrats	17
A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice	17
Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy	16
Genetic background determines renal response to chronic lithium treatment in female mice	16
Dose-dependent progression of multiple low-dose streptozotocin-induced diabetes in mice	15
Chronic binge alcohol and ovariectomy dysregulate omental adipose tissue metaboproteome in simian immunodeficiency virus-infected female macaques	14
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways	14
Integrated analysis of transcriptome profiling of lncRNAs and mRNAs in livers of type 2 diabetes mellitus	13
The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats	12
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	11
Knockout of Hsp70 genes significantly affects locomotion speed and gene expression in leg skeletal muscles of Drosophila melanogaster	11
Cardiac biomarker responses following high-intensity interval and continuous exercise: the influence of ACE-I/D gene polymorphism and training status in men	11
Characteristics of circular RNAs expression of peripheral blood mononuclear cells in humans with coronary artery disease	11
Changes in environmental stress over COVID-19 pandemic likely contributed to failure to replicate adiposity phenotype associated with Krtcap3	11
Single-cell profiling of the peripheral blood immune landscape during mid- and late-stage pregnancy	10
Platelet proteome dynamics in hibernating 13-lined ground squirrels	10

Gene expression profile and injury sites in mice treated with Shiga toxin 2 and lipopolysaccharide as a Shiga toxin-associated hemolytic uremic syndrome model	9
MicroRNA-499-5p promotes vascular smooth muscle cell proliferation and migration via inhibiting SOX6	9
Physiological, biochemical, and genome-wide expression patterns during graded normobaric hypoxia in healthy individuals	9
Transcriptomics and proteomics revealed sex differences in human pulmonary microvascular endothelial cells	8
Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury	8
Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise	8
Fecal dysbiosis and inflammation in intestinal-specific Cftr knockout mice on regimens preventing intestinal obstruction	8
Lost in translation? Evidence for a muted proteomic response to thermal stress in a stenothermal Antarctic fish and possible evolutionary mechanisms	7
Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity	7
Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients	7
Retraction for Huang et al., PEA15-HKII, stabilized by U2AF2, form a molecular switch governing cellular fate after spinal cord injury via MAPK pathway	7
Host-microbiota interactions contributing to the heterogeneous tumor microenvironment in colorectal cancer	7
Gut microbiota of wild fish as reporters of compromised aquatic environments sleuthed through machine learning	7
The genetic regulation of the gastric transcriptome is associated with metabolic and obesity-related traits and diseases	7
Off the shelf: Regulation of fish blood pH through ionocyte membrane remodelling and protein translocation without additional synthesis	7
RNA sequencing indicates age-dependent shifts in the cardiac fibroblast transcriptome between fetal, neonatal, and adult developmental ages	7
Age-dependent transcriptional alterations in cardiac endothelial cells	6
Differences in the bacterial communities along the intestinal tract of juvenile channel (Ictalurus punctatus) and hybrid (I. punctatus× I. furcatus) catfish	6
Podocyte cell-specific Npr1 is required for blood pressure and renal homeostasis in male and female mice: role of sex-specific differences	6
Lung proinflammatory microRNA and cytokine expression in a mouse model of allergic inflammation: role of sex chromosome complement and gonadal hormones	6
Low carbohydrate availability promotes a distinct circulating microRNA profile 24 h following aerobic exercise	6
Extracellular vesicle-mediated transfer of lncRNA CLDN10-AS1 aggravates low-density lipoprotein-induced vascular endothelial injury	6
Computational modeling of the synergistic role of GCN2 and the HPA axis in regulating the integrated stress response in the central circadian timing system	6
Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia	6
Maternal-fetal interfaces transcriptome changes associated with placental insufficiency and a novel gene therapy intervention	6
Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates	6
Vacuole membrane protein 1 and miRNA-21: are they reliable partners to rescue acute kidney injury?	6
Myocardial transcriptomic and proteomic landscapes across the menopausal continuum in a murine model of chemically-induced accelerated ovarian failure	5
Drivers of transcriptional variance in human intestinal epithelial organoids	5
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice	5
Chronic jetlag-induced alterations in pancreatic diurnal gene expression	5
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages	5
Immune and metabolic challenges induce changes in pain sensation and related pathways in the hypothalamus	5
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study	5
The effect of high-fiber diet based on gut microbiota in patients with chronic heart failure	5
Epigenetic fluctuations underlie gene expression timescales and variability	5
A genetic variant associated with Aquaporin 3 expression is correlated to in-hospital death in COVID-19 patients with extracellular hyperosmolality	5
Knockdown of deoxythymidylate kinase suppresses progression and epithelial-mesenchymal-transition of lung adenocarcinoma via STAT3 signaling	5