OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Genomics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Artificial intelligence and machine learning to fight COVID-19	391
The COVID-19 pandemic: a global health crisis	269
SARS-CoV-2, ACE2 expression, and systemic organ invasion	99
Harnessing innate immunity to eliminate SARS-CoV-2 and ameliorate COVID-19 disease	75
Sleep fragmentation increases blood pressure and is associated with alterations in the gut microbiome and fecal metabolome in rats	59
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project	54
Oxytocin’s anti-inflammatory and proimmune functions in COVID-19: a transcriptomic signature-based approach	30
Implementation of convolutional neural network approach for COVID-19 disease detection	30
Silencing of MYH7 ameliorates disease phenotypes in human iPSC-cardiomyocytes	29
Cell dormancy plasticity: quiescence deepens into senescence through a dimmer switch	26
Cell-free DNA and RNA—measurement and applications in clinical diagnostics with focus on metabolic disorders	22
Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19	21
Nrf2 signaling in heart failure: expression of Nrf2, Keap1, antioxidant, and detoxification genes in dilated or ischemic cardiomyopathy	18
Drivers of transcriptional variance in human intestinal epithelial organoids	17
Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision medicine to subclassify NAFLD	17
Functional genomics analysis of human colon organoids identifies key transcription factors	16
Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia	16
Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in vitro-produced embryos	15
Transcriptomic signature of fasting in human adipose tissue	14
Machine learning-based classification and diagnosis of clinical cardiomyopathies	14
Methylation of histone 4’s lysine 20: a critical analysis of the state of the field	14
Can cilia provide an entry gateway for SARS-CoV-2 to human ciliated cells?	13
Lysine demethylase KDM6B regulates HIF-1α-mediated systemic and cellular responses to intermittent hypoxia	12
Frequency and management of medically actionable incidental findings from genome and exome sequencing data: a systematic review	12
Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity	12

Genomic and epigenomic active vitamin D responses in human colonic organoids	11
Molecular signatures of muscle growth and composition deciphered by the meta-analysis of age-related public transcriptomics data	11
High-fat diet negatively impacts both metabolic and behavioral health in outbred heterogeneous stock rats	11
Identification of a peripheral blood gene signature predicting aortic valve calcification	11
Circulating and tissue matricellular RNA and protein expression in calcific aortic valve disease	11
Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise	10
Integration of metabolomics and transcriptomics reveals convergent pathways driving radiation-induced salivary gland dysfunction	10
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	10
Time-course analysis of the effect of embedded metal on skeletal muscle gene expression	10
Probing metabolic memory in the hepatic response to fasting	10
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways	10
Gene expression of the IGF hormones and IGF binding proteins across time and tissues in a model reptile	9
Characteristics of circular RNAs expression of peripheral blood mononuclear cells in humans with coronary artery disease	9
Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity	9
Fetal ovine skeletal and cardiac muscle transcriptomics are differentially altered by increased maternal cortisol during gestation	9
eQTL variants in COL22A1 are associated with muscle injury in athletes	9
Genetic ablation of bone marrow beta-adrenergic receptors in mice modulates miRNA-transcriptome networks of neuroinflammation in the paraventricular nucleus	9
Difference in potential DNA methylation impact on gene expression between fast- and slow-type myofibers	9
mRatBN7.2: familiar and unfamiliar features of a new rat genome reference assembly	8
Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension	8
High-resolution analysis of differential gene expression during skeletal muscle atrophy and programmed cell death	8
Platelet proteome dynamics in hibernating 13-lined ground squirrels	8
Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice	8
Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats	7
Distribution of cardiomyocyte-selective adeno-associated virus serotype 9 vectors in swine following intracoronary and intravenous infusion	7
Progesterone-dependent and progesterone-independent modulation of luminal epithelial transcription to support pregnancy in cattle	7
Chronic jetlag-induced alterations in pancreatic diurnal gene expression	7
Gut microbiota of wild fish as reporters of compromised aquatic environments sleuthed through machine learning	7
Human endogenous retroviruses: our genomic fossils and companions	7