OOIR: Observatory of International Research

Papers

(The TQCC of Physiological Genomics is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Prolonged obesity alters males’ adipose profile: implications for disease?	36
Editorial Board	30
Assessing the impact of boldine on the gastrocnemius using multiomics profiling at 7 and 28 days post-complete spinal cord injury in young male mice	26
Identification of shared and disease-specific intratumoral microbiome-host gene associations in gastrointestinal tumors	26
Impact of stress phenotype, elevated temperature, and bacterin exposure on male Atlantic salmon (Salmo salar) growth, stress, and immune biomarker gene expression	25
Analysis of a genetic region affecting mouse body weight	23
Single-cell RNA sequencing reveals genes relevant to periodontal therapy and periodontitis	21
NR4A2-driven metabolic reprogramming in the heart: from adaptive response to maladaptive remodeling	21
Investigative power of genomic informational field theory relative to genome-wide association studies for genotype-phenotype mapping	18
The expression profile of 79 genes from 107 viruses revealed new insights into disease susceptibility in rats, mice, and muskrats	17
Obesity as an epigenetic continuum: developmental roots, adipose remodeling, and the limits of reversibility	17
A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice	15
Deciphering taxonomic and functional patterns of microbial communities associated with the tiger tail seahorse (Hippocampus comes)	15
Transcriptomic responses of equine skeletal muscle to acute exercise in a hot environment	14
Dose-dependent progression of multiple low-dose streptozotocin-induced diabetes in mice	14
Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy	13
Cardiac biomarker responses following high-intensity interval and continuous exercise: the influence of ACE-I/D gene polymorphism and training status in men	13
Changes in environmental stress over COVID-19 pandemic likely contributed to failure to replicate adiposity phenotype associated with Krtcap3	13
Mapping cardiac electrical abnormalities in rodents	13
Complementary human gene interaction maps from radiation hybrids and CRISPRi	12
Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice	11
Gut microbiome and host interactions in catfish: hybridization structures bacterial communities along catfish intestinal tract	11
Single-cell profiling of the peripheral blood immune landscape during mid- and late-stage pregnancy	11
MicroRNA-499-5p promotes vascular smooth muscle cell proliferation and migration via inhibiting SOX6	11
Transcriptomics and proteomics revealed sex differences in human pulmonary microvascular endothelial cells	11

Knockout of Hsp70 genes significantly affects locomotion speed and gene expression in leg skeletal muscles of Drosophila melanogas	11
Fecal dysbiosis and inflammation in intestinal-specific Cftr knockout mice on regimens preventing intestinal obstruction	10
Physiological, biochemical, and genome-wide expression patterns during graded normobaric hypoxia in healthy individuals	10
Retraction for Huang et al., PEA15-HKII, stabilized by U2AF2, form a molecular switch governing cellular fate after spinal cord injury via MAPK pathway	10
Off the shelf: Regulation of fish blood pH through ionocyte membrane remodelling and protein translocation without additional synthesis	10
Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury	10
Seasonal changes in the transcriptome of bat eyes reveal adaptive changes to exploit summer twilight	10
Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients	10
The microbiome shaping cancer development, progression, and therapeutic response	10
Host-microbiota interactions contributing to the heterogeneous tumor microenvironment in colorectal cancer	10
Maternal-fetal interfaces transcriptome changes associated with placental insufficiency and a novel gene therapy intervention	9
Connecting genes to physiology: the first 25 years of Physiological Genomics	9
Low carbohydrate availability promotes a distinct circulating microRNA profile 24 h following aerobic exercise	9
Lost in translation? Evidence for a muted proteomic response to thermal stress in a stenothermal Antarctic fish and possible evolutionary mechanisms	9
Vacuole membrane protein 1 and miRNA-21: are they reliable partners to rescue acute kidney injury?	9
Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia	9
Decoding exercise adaptation through multidimensional biocircuitry	9
Correction for Gomez et al., volume 57, 2025, p. 65–79	8
Lung proinflammatory microRNA and cytokine expression in a mouse model of allergic inflammation: role of sex chromosome complement and gonadal hormones	8
Extracellular vesicle-mediated transfer of lncRNA CLDN10-AS1 aggravates low-density lipoprotein-induced vascular endothelial injury	8
Gut microbial composition and diversity varies by CREBRF genotype among Samoan infants	8
Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates	8
The genetic regulation of the gastric transcriptome is associated with metabolic and obesity-related traits and diseases	8
Differences in the bacterial communities along the intestinal tract of juvenile channel (Ictalurus punctatus) and hybrid (I. punctatus× I. furcatus) catfish	8
Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study	7
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice	7
Computational modeling of the synergistic role of GCN2 and the HPA axis in regulating the integrated stress response in the central circadian timing system	7
The skeletal muscle of aged male mice exhibits sustained growth regulatory transcriptional profile following glucocorticoid exposure compared with young males	7
Embryonic hypoxia alters cardiac gene expression patterns in American alligators, Alligator mississippiensis	7
Multiomic characterization of DNA released after airway exposure to allergens and nanoparticles reveals selective export of repetitive and fragile site DNA	7
Rodents exposed to placental ischemia in utero display sex differences in brain miRNA expression, mitochondrial function, and blood pressure in adulthood	7
Knockdown of deoxythymidylate kinase suppresses progression and epithelial-mesenchymal-transition of lung adenocarcinoma via STAT3 signaling	7
Systems genomics reveals age- and sex-dependent metabolic dysregulation from Glo1 reduction in mice	7
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages	7
Podocyte cell-specific Npr1 is required for blood pressure and renal homeostasis in male and female mice: role of sex-specific differences	7
Immune and metabolic challenges induce changes in pain sensation and related pathways in the hypothalamus	7
Myocardial transcriptomic and proteomic landscapes across the menopausal continuum in a murine model of chemically induced accelerated ovarian failure	7
A genetic variant associated with aquaporin 3 expression is correlated to in-hospital death in COVID-19 patients with extracellular hyperosmolality	7
The effect of high-fiber diet based on gut microbiota in patients with chronic heart failure	6
White-throated sparrow (Zonotrichia albicollis) liver and pectoralis flight muscle transcriptomic changes in preparation for migration	6
Specific circulating miRNAs are associated with plasma lipids in a healthy American cohort	6
Transcriptomics and metabolomics analysis reveal cell subpopulations of trophoblast cells associated with preeclampsia	6
Editorial Board	6
METTL3-mediated m6A modification promotes processing and maturation of pri-miRNA-19a to facilitate nasopharyngeal carcinoma cell proliferation and invasion	6
Subdiaphragmatic vagal nerve stimulation attenuates the development of hypertension and alters nucleus of the solitary tract transcriptional networks in the spontaneously hypertensive rat	6
microRNA profiles in slow and fast skeletal muscle fibers	6
Transcriptome profiling suggests molecular sexual dimorphism in lumbosacral dorsal root ganglia and sex-specific mechanisms underlying visceral pain	6
Transcriptomic Profiling Reveals Immunometabolic Gene Regulation during a 24-Hour Cold Exposure Survival Simulation in Humans	6
Corrigendum for Medvar et al., Volume 48, 2016, p. 502–512	6
Changes in liver and lung antioxidant and mitochondrial biogenesis gene expression in decompression sickness resistant rats	6

Multidimensional characterization of the tumor microenvironment profiles in lung squamous cell carcinoma	6
PANoptosis in vascular smooth muscle cells regulated by TNF-α/IL-1β can be a new target for alleviating the progression of abdominal aortic aneurysm	6
Endothelial to mesenchymal transition in neonatal hyperoxic lung injury: role of sex as a biological variable	6