OOIR: Observatory of International Research

Papers

(The TQCC of Pulmonary Pharmacology & Therapeutics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Dual-histamine receptor blockade with cetirizine - famotidine reduces pulmonary symptoms in COVID-19 patients	63
Sequential doxycycline and colchicine combination therapy in Covid-19: The salutary effects	52
Myricetin inhibits TNF-α-induced inflammation in A549 cells via the SIRT1/NF-κB pathway	49
Mepolizumab effectiveness on small airway obstruction, corticosteroid sparing and maintenance therapy step-down in real life	45
The immunomodulatory effects of macrolide antibiotics in respiratory disease	41
Antihistamines and azithromycin as a treatment for COVID-19 on primary health care – A retrospective observational study in elderly patients	35
Asthmatic children and MDI verbal inhalation technique counseling	33
Tofacitinib reduces mortality in coronavirus disease 2019 Tofacitinib in COVID-19	32
Mdivi-1 attenuates lipopolysaccharide-induced acute lung injury by inhibiting MAPKs, oxidative stress and apoptosis	31
Small-molecule drugs for cystic fibrosis: Where are we now?	27
The anti-inflammatory effects of cannabidiol and cannabigerol alone, and in combination	24
Glucagon-like peptide 1 receptor (GLP-1R) agonist relieved asthmatic airway inflammation via suppression of NLRP3 inflammasome activation in obese asthma mice model	22
Inhaled nintedanib is well-tolerated and delivers key pharmacokinetic parameters required to treat bleomycin-induced pulmonary fibrosis	22
Baicalin ameliorates cigarette smoke-induced airway inflammation in rats by modulating HDAC2/NF-κB/PAI-1 signalling	22
Bergenin-activated SIRT1 inhibits TNF-α-induced proinflammatory response by blocking the NF-κB signaling pathway	21
Advanced spray dried proliposomes of amphotericin B lung surfactant-mimic phospholipid microparticles/nanoparticles as dry powder inhalers for targeted pulmonary drug delivery	21
Aerosolized Beractant in neonatal respiratory distress syndrome: A randomized fixed-dose parallel-arm phase II trial	20
Effects of corticosteroids on Covid-19 patients: A systematic review and meta-analysis on clinical outcomes	19
Glabridin attenuates airway inflammation and hyperresponsiveness in a mice model of ovalbumin-induced asthma	18
Tetrahydropalmatine protects against acute lung injury induced by limb ischemia/reperfusion through restoring PI3K/AKT/mTOR-mediated autophagy in rats	17
Common molecular pathways targeted by nintedanib in cancer and IPF: A bioinformatic study	17
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice	17
Dihydroquercetin attenuates lipopolysaccharide-induced acute lung injury through modulating FOXO3-mediated NF-κB signaling via miR-132–3p	16
Significant improvement in lung function and asthma control after benralizumab treatment for severe refractory eosinophilic asthma	16
CXCR1 correlates to poor outcomes of EGFR-TKI against advanced non-small cell lung cancer by activating chemokine and JAK/STAT pathway	15

Gentiopicroside ameliorates ovalbumin-induced airway inflammation in a mouse model of allergic asthma via regulating SIRT1/NF-κB signaling pathway	15
Rapid effect of benralizumab for severe asthma with chronic rhinosinusitis with nasal polyps	15
A randomized, double-blind study to compare the efficacy and safety of two doses of mometasone furoate delivered via Breezhaler® or Twisthaler® in patients with asthma	14
Inhaled delivery of a lipid nanoparticle encapsulated messenger RNA encoding a ciliary protein for the treatment of primary ciliary dyskinesia	14
Comparative anti-inflammatory effect of curcumin at air-liquid interface and submerged conditions using lipopolysaccharide stimulated human lung epithelial A549 cells	14
Efficacy and safety of combined isoniazid-rifampicin-pyrazinamide-levofloxacin dry powder inhaler in treatment of pulmonary tuberculosis: A randomized controlled trial	14
Chrysin prevents lipopolysaccharide-induced acute lung injury in mice by suppressing the IRE1α/TXNIP/NLRP3 pathway	14
Long non-coding RNA LINC01224 promotes progression and cisplatin resistance in non-small lung cancer by sponging miR-2467	13
Effectiveness of mepolizumab therapy in patients with severe eosinophilic asthma: Austrian real-life data	13
Are short courses of antibiotic therapy as effective as standard courses for COPD exacerbations? A systematic review and meta-analysis	13
An overview of the biology of a long-acting inhaled treprostinil prodrug	13
The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells	12
Development of an inhaled anti-TSLP therapy for asthma	12
Clofazimine for treatment of multidrug-resistant non-tuberculous mycobacteria	11
The effects of fatty acid amide hydrolase and monoacylglycerol lipase inhibitor treatments on lipopolysaccharide-induced airway inflammation in mice	11
Effects of sildenafil on right ventricle remodelling in Portopulmonary hypertension	11
Investigating the effect of TRPV4 inhibition on pulmonary-vascular barrier permeability following segmental endotoxin challenge	11
Effect of piperlongumine during exposure to cigarette smoke reduces inflammation and lung injury	11
Tolerability of nintedanib-related diarrhea in patients with idiopathic pulmonary fibrosis	10
Epimedin C modulates the balance between Th9 cells and Treg cells through negative regulation of noncanonical NF-κB pathway and MAPKs activation to inhibit airway inflammation in the ovalbumin–induced	10
“The possible implication of endothelin in the pathology of COVID-19-induced pulmonary hypertension”	9
Inhalation: A means to explore and optimize nintedanib's pharmacokinetic/pharmacodynamic relationship	9
Leukotriene inhibition and the risk of lung cancer among U.S. veterans with asthma	9
Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-19	9
Benralizumab improves patient reported outcomes and functional parameters in difficult-to-treat patients with severe asthma: Data from a real-life cohort	9
Pharmacokinetics of indacaterol, glycopyrronium and mometasone furoate following once-daily inhalation as a combination in healthy subjects	8
Time-resolved proteome and transcriptome of paraquat-induced pulmonary fibrosis	8
Multiple single nucleotide polymorphisms of the transient receptor potential vanilloid 1 (TRPV1) genes associate with cough sensitivity to capsaicin in healthy subjects	8
The ALPACA study: (In)Appropriate LAMA prescribing in asthma: A cohort analysis	8
Treatment of respiratory viral infections through inhalation therapeutics: Challenges and opportunities	7
LncRNA STARD13-AS blocks lung squamous carcinoma cells growth and movement by targeting miR-1248/C3A	7
Characteristics of patients with severe asthma who experienced treatment failure with omalizumab	7
HDAC8-inhibitor PCI-34051-induced exosomes inhibit human bronchial smooth muscle cell proliferation via miR-381-3p mediated TGFB3	7
Scope of adjuvant therapy using roflumilast, a PDE-4 inhibitor against COVID-19	7
β-sitosterol targets glucocorticoid receptor to reduce airway inflammation and remodeling in allergic asthma	7
Diallyl disulfide prevents cigarette smoke-induced emphysema in mice	7
Pharmacokinetics of mometasone furoate delivered via two dry powder inhalers	7
Real-life safety and efficacy of omalizumab in Japanese patients with severe allergic asthma who were subjected to dosing table revision or expansion: A post-marketing surveillance	7
Ceiling effect of beclomethasone/formoterol/glycopyrronium triple fixed-dose combination in COPD: A translational bench-to-bedside study	7
Determinants of response to bronchodilator in patients with cough variant asthma- A randomized, single-blinded, placebo-controlled study	7