Pulmonary Pharmacology & Therapeutics

Papers
(The median citation count of Pulmonary Pharmacology & Therapeutics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Myricetin inhibits TNF-α-induced inflammation in A549 cells via the SIRT1/NF-κB pathway58
The immunomodulatory effects of macrolide antibiotics in respiratory disease56
Sequential doxycycline and colchicine combination therapy in Covid-19: The salutary effects53
Antihistamines and azithromycin as a treatment for COVID-19 on primary health care – A retrospective observational study in elderly patients40
Tofacitinib reduces mortality in coronavirus disease 2019 Tofacitinib in COVID-1936
Glucagon-like peptide 1 receptor (GLP-1R) agonist relieved asthmatic airway inflammation via suppression of NLRP3 inflammasome activation in obese asthma mice model32
The anti-inflammatory effects of cannabidiol and cannabigerol alone, and in combination31
Small-molecule drugs for cystic fibrosis: Where are we now?31
Baicalin ameliorates cigarette smoke-induced airway inflammation in rats by modulating HDAC2/NF-κB/PAI-1 signalling27
Aerosolized Beractant in neonatal respiratory distress syndrome: A randomized fixed-dose parallel-arm phase II trial25
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice23
Effects of corticosteroids on Covid-19 patients: A systematic review and meta-analysis on clinical outcomes22
Gentiopicroside ameliorates ovalbumin-induced airway inflammation in a mouse model of allergic asthma via regulating SIRT1/NF-κB signaling pathway18
Clofazimine for treatment of multidrug-resistant non-tuberculous mycobacteria17
CXCR1 correlates to poor outcomes of EGFR-TKI against advanced non-small cell lung cancer by activating chemokine and JAK/STAT pathway17
The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells17
Chrysin prevents lipopolysaccharide-induced acute lung injury in mice by suppressing the IRE1α/TXNIP/NLRP3 pathway16
An overview of the biology of a long-acting inhaled treprostinil prodrug15
Are short courses of antibiotic therapy as effective as standard courses for COPD exacerbations? A systematic review and meta-analysis15
Development of an inhaled anti-TSLP therapy for asthma15
Long non-coding RNA LINC01224 promotes progression and cisplatin resistance in non-small lung cancer by sponging miR-246715
Efficacy and safety of combined isoniazid-rifampicin-pyrazinamide-levofloxacin dry powder inhaler in treatment of pulmonary tuberculosis: A randomized controlled trial15
Inhaled delivery of a lipid nanoparticle encapsulated messenger RNA encoding a ciliary protein for the treatment of primary ciliary dyskinesia14
Epimedin C modulates the balance between Th9 cells and Treg cells through negative regulation of noncanonical NF-κB pathway and MAPKs activation to inhibit airway inflammation in the ovalbumin–induced14
Pulmonary drug delivery for acute respiratory distress syndrome13
Effects of sildenafil on right ventricle remodelling in Portopulmonary hypertension12
Time-resolved proteome and transcriptome of paraquat-induced pulmonary fibrosis12
Real-world safety profiles of pirfenidone and nintedanib in idiopathic pulmonary fibrosis patients12
Diallyl disulfide prevents cigarette smoke-induced emphysema in mice11
Treatment of respiratory viral infections through inhalation therapeutics: Challenges and opportunities11
Leukotriene inhibition and the risk of lung cancer among U.S. veterans with asthma11
β-sitosterol targets glucocorticoid receptor to reduce airway inflammation and remodeling in allergic asthma11
HDAC8-inhibitor PCI-34051-induced exosomes inhibit human bronchial smooth muscle cell proliferation via miR-381-3p mediated TGFB310
Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-1910
“The possible implication of endothelin in the pathology of COVID-19-induced pulmonary hypertension”10
WITHDRAWN: Oncogenic lncRNA MALAT-1 recruits E2F1 to upregulate RAD51 expression and thus promotes cell autophagy and tumor growth in non-small cell lung cancer9
The ALPACA study: (In)Appropriate LAMA prescribing in asthma: A cohort analysis9
An open label trial of nemiralisib, an inhaled PI3 kinase delta inhibitor for the treatment of Activated PI3 kinase Delta Syndrome9
CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis8
Ceiling effect of beclomethasone/formoterol/glycopyrronium triple fixed-dose combination in COPD: A translational bench-to-bedside study8
Serum exosomal m6A demethylase FTO promotes gefitinib resistance in non-small cell lung cancer by up-regulating FLRT3, PTGIS and SIRPα expression8
Scope of adjuvant therapy using roflumilast, a PDE-4 inhibitor against COVID-197
Pharmacokinetics of mometasone furoate delivered via two dry powder inhalers7
Characteristics of patients with severe asthma who experienced treatment failure with omalizumab7
Statins’ still controversial role in pulmonary fibrosis: What does the evidence show?7
Comparison of l-Carnitine and l-Carnitine HCL salt for targeted lung treatment of pulmonary hypertension (PH) as inhalation aerosols: Design, comprehensive characterization, in vitro 2D/3D cell cultur6
Use of nintedanib in interstitial lung disease other than idiopathic pulmonary fibrosis: much caution is warranted6
Treatment of pulmonary hypertension in patients with Hereditary Hemorrhagic Telangiectasia – A case series and systematic review6
Effect of functional principle, delivery technique, and connection used on aerosol delivery from different nebulizers: An in-vitro study6
Impacts of deficiency in vitamin D derivatives on disease severity in adult bronchial asthma patients6
The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant6
Pyrroloquinoline quinone (PQQ) improves pulmonary hypertension by regulating mitochondrial and metabolic functions6
Dose bridging data for mometasone furoate in once-daily fixed-dose inhaled combinations of mometasone furoate/indacaterol and mometasone furoate/ indacaterol/glycopyrronium in patients with asthma6
The promoting role of Cx43 on the proliferation and migration of arterial smooth muscle cells for angiotensin II-dependent hypertension6
Effects of inhaled JAK inhibitor GDC-4379 on exhaled nitric oxide and peripheral biomarkers of inflammation6
Evaluation of high dose N- Acetylcysteine on airway inflammation and quality of life outcomes in adults with bronchiectasis: A randomised placebo-controlled pilot study5
Amygdalin epimers exert discrepant anti-pulmonary fibrosis activity via inhibiting TGF-β1/Smad2/3 pathway5
Inhaled bronchodilators use and clinical course of adult inpatients with Covid-19 pneumonia in Spain: A retrospective cohort study5
Mechanistic insights into the amelioration effects of lipopolysaccharide-induced acute lung injury by baicalein: An integrated systems pharmacology study and experimental validation5
Sildenafil for idiopathic pulmonary fibrosis: A systematic review and meta-analysis5
Inflammatory and contractile profile in LPS-challenged equine isolated bronchi: Evidence for IL-6 as a potential target against AHR in equine asthma5
A retro-inverso modified peptide alleviated ovalbumin-induced asthma model by affecting glycerophospholipid and purine metabolism of immune cells5
Differential redox proteomic profiles of serum from severe asthma patients after one month of benralizumab and mepolizumab treatment5
May a different kinetic mode explain the high efficacy/safety profile of inhaled budesonide?5
Effect of centrally and peripherally acting GABAB agonism on the healthy human cough reflex5
Haemodynamic effects of PAH-targeted therapies in pulmonary hypertension due to lung disease: A systematic review and meta-analysis4
The role of TRPA1 and TRPV4 channels in bronchoconstriction and plasma extravasation in airways of rats treated with captopril4
Management of severe asthma during the first lockdown phase of SARS-CoV-2 pandemic: Tips for facing the second wave4
Protective effects of adipose-derived biogenic nanoparticles on the pulmonary microvascular endothelial barrier in mice with ventilator-induced lung injury via the TRPV4/ROCK1 signalling pathway4
The roles of immune system and autoimmunity in pulmonary arterial hypertension: A review4
Commercial α1-antitrypsin preparations markedly differ in their potential to inhibit the ATP-induced release of monocytic interleukin-1β4
Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats4
Safety and usefulness of nebulized liposomal amphotericin B: Systematic scoping review4
Hypoxia-induced antizyme inhibitors 2 regulates cisplatin resistance through epithelia-mesenchymal transition pathway in non-small cell lung cancer4
Esketamine inhaled as dry powder: Pharmacokinetic, pharmacodynamic and safety assessment in a preclinical study4
Which LABA/LAMA should be chosen in COPD patients in real life?4
Nebulized amphotericin B for preventing exacerbations in allergic bronchopulmonary aspergillosis: A systematic review and meta-analysis4
A phase 1, randomized study to evaluate safety, tolerability, and pharmacokinetics of GDC-3280, a potential novel anti-fibrotic small molecule, in healthy subjects4
Evaluation of efficacy of nebulized low molecular weight heparin as an adjunctive extra treatment for acute mild-moderate asthma attack; a randomized clinical trial study4
The tolerability and efficacy of antifibrotic therapy in patients with idiopathic pulmonary fibrosis: Results from a real-world study4
Inhaled nebulised unfractionated heparin (UFH) for the treatment of hospitalised patients with COVID-19: A randomised controlled pilot study4
Dihydroquercetin (DHQ) ameliorates LPS-induced acute lung injury by regulating macrophage M2 polarization through IRF4/miR-132-3p/FBXW7 axis4
Evaluation of the prophylactic effect of hydroxychloroquine on people in close-contact with patients with COVID-194
Up-regulation of PPAR-γ involved in the therapeutic effect of icariin on cigarette smoke-induced inflammation4
The impact of nintedanib and pirfenidone on lung function and survival in patients with idiopathic pulmonary fibrosis in real-life setting3
Comparing the outcomes of intrapleural fibrinolytic and DNase therapy versus intrapleural fibrinolytic or DNase therapy: A systematic review and meta-analysis3
Differential effects of dexamethasone and roflumilast on asthma in mice with or without short cigarette smoke exposure3
Preventive effect of LCZ696 on hypoxic pulmonary hypertension in rats via regulating the PI3K/AKT signaling pathway3
Risk factors associated with increased discontinuation rate of trimethoprim–sulfamethoxazole used as a primary prophylaxis for Pneumocystis pneumonia: A retrospective cohort study3
Preliminary study regarding the predicted body weight-based dexamethasone therapy in patients with COVID-19 pneumonia3
Demethyleneberberine alleviates Pseudomonas aeruginosa-induced acute pneumonia by inhibiting the AIM2 inflammasome and oxidative stress3
m6A-modified miR-143-3p inhibits epithelial mesenchymal transition in bronchial epithelial cells and extracellular matrix production in lung fibroblasts by targeting Smad33
Considerations into pharmacogenomics of COVID-19 pharmacotherapy: Hope, hype and reality3
Safety and pharmacokinetic profile of pretomanid in healthy Chinese adults: Results of a phase I single dose escalation study3
Weight loss in nintedanib-treated patients with idiopathic pulmonary fibrosis3
Transcriptional factor MAZ promotes cisplatin-induced DNA damage repair in lung adenocarcinoma by regulating NEIL33
Effectiveness of inhalation technique assessment service for patients with Respimat® inhaler3
Reduction in asthma exacerbation rate after mepolizumab treatment initiation in patients with severe asthma: A real-world database study in Japan3
Allopurinol treatment reduced vascular remodeling and improved vascular functions in monocrotaline-induced pulmonary hypertensive rats3
Serum dipeptidyl peptidase-4 and eosinophil cationic protein levels in patients of bronchial asthma3
Tolerability and efficacy of second-line antifibrotics in patients with idiopathic pulmonary fibrosis3
Corrigendum to “Myricetin inhibits TNF-α-induced inflammation in A549 cells via the SIRT1/NF-κB pathway” [Pulm. Pharmacol. Therapeut. 65 (2020) 102000]2
IRE1α/XBP-1 promotes β-catenin signaling activation of airway epithelium in lipopolysaccharide-induced acute lung injury2
Efficacy and safety of selexipag, an oral prostacyclin receptor agonist for the treatment of pulmonary hypertension: A meta-analysis2
Nontuberculous mycobacterial (NTM) infections in bronchiectasis patients: A retrospective US registry cohort study2
Safety and tolerability of inhaled antibiotics in patients with bronchiectasis2
Pharmacokinetics and exposure-efficacy relationships of omalizumab in patients with nasal polyps2
Anlotinib prove to be a potential therapy for the treatment of pulmonary fibrosis complicated with lung adenocarcinoma2
Chronic obstructive pulmonary disease and emerging ER stress-related therapeutic targets2
TPMT and HLA-DQA1-HLA-DRB genetic profiling to guide the use of azathioprine in the treatment of interstitial lung disease: First experience2
Knockdown of HDAC10 inhibits POLE2-mediated DNA damage repair in NSCLC cells by increasing SP1 acetylation levels2
The impact of SARS-COV2 pandemic on the management oF IPF patients: Our narrative experience2
Activating transcription factor 6 in the endothelial context2
Mesenchymal stromal cells-based therapy in a murine model of elastase-induced emphysema: Simvastatin as a potential adjuvant in cellular homing2
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway2
Relative bioavailability of budesonide/glycopyrrolate/formoterol fumarate triple therapy delivered using next generation propellants with low global warming potential2
SIRT3 alleviates sepsis-induced acute lung injury by inhibiting pyroptosis via regulating the deacetylation of FoxO3a2
Enlightening clinical and therapeutic heterogeneity in thoracic actinomycosis: A review in bronchiectasis and non-bronchiectasis patients2
Efficacy and safety of sequential combination therapy for pulmonary arterial hypertension: A meta-analysis of Randomized-Controlled Trials2
Patients with moderate to severe COVID-19 outcomes on remdesivir according to baseline 4C mortality score2
Efficacy and safety of house dust mite subcutaneous immunotherapy in polysensitized children with allergic asthma2
An expert panel delphi consensus statement on patient selection and management for transitioning between oral and inhaled treprostinil2
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