International Journal of Toxicology

Papers
(The TQCC of International Journal of Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Safety Assessment of Adenosine as Used in Cosmetics19
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats17
Isopropyl Lanolate15
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics13
Mink Oil12
I Wish I Had Known That! Impactful Guidance and Perspectives for a Fulfilling Career in Toxicology12
Effect of Chronic Consumption of Fluoridated Water on Sciatic Nerve Conduction Velocity in Male Wistar Rats11
In Utero Exposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment9
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro9
Editor’s Response to Jorge A. García-Valenzuela and Martha R. Baez-Gaxiola8
Sodium α-Olefin Sulfonates8
A Characterization of the Nonclinical Pharmacology and Toxicology of Aficamten, a Reversible Allosteric Inhibitor of Cardiac Myosin8
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations8
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics8
Glycol Stearate and Glycol Stearate SE7
Editor’s Note7
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics7
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development7
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review7
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics7
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics6
Amended Safety Assessment of Acid Violet 43 as Used in Cosmetics6
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate6
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics6
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients6
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species6
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity6
A Commentary on Fasting of Nonclinical Research Animals6
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics6
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii6
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice6
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex5
Lard and Lard-Derived Ingredients5
Polyamino Sugar Condensate5
Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics5
Amyl Acetate and Isoamyl Acetate5
Toxicology Certification: The Need, the Value, and an Evolving Landscape5
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats4
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey4
Thank you to our ad hoc reviewers!4
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review4
Book Review: Reproductive and Developmental Toxicology Third Edition4
Amended Safety Assessment of Methylchloroisothiazolinone and Methylisothiazolinone as Used in Cosmetics4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines4
Comparative Analyses of the Influences of Vehicles on Selected Biological Parameters Following Single-Dose Oral Administration in Sprague-Dawley Rats4
Safety Assessment of Methylxanthines as Used in Cosmetics4
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety4
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration4
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults4
Book Review: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals3
Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers3
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System3
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics3
Safety Assessment of Alkyl Amide MIPA Ingredients as Used in Cosmetics3
Book Review: Haschek and Rousseaux’s Handbook of Toxicologic Pathology3
Final Amended Safety Assessment of Sodium Sulfate as Used in Cosmetics3
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue3
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples3
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models3
Exploring the Biological Effects of Polystyrene Nanoplastics on Spermatogenesis: Insights From Transcriptomic Analysis in Mouse Spermatocytes3
Effects of Vanadium Inhalation and Sweetened Beverage Ingestion in Mice: Morphological and Biochemical Changes in the Liver3
Quaternium-18 and Quaternium-18 Bentonite3
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations3
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics2
BHT – Butylated Hydroxytoluene2
Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database2
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics2
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics2
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate2
Editor’s note2
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research2
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury2
Book Reviews2
Eleventh Triennial Toxicology Salary Survey2
Biotin2
Editor’s note2
Mutagenesis and Carcinogenesis Risk Evaluation for AAV and Lentiviral Gene Therapies2
Recent Advances in Drug Discovery Toxicology2
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys (Macaca mulatta)2
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD2
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,2
Hexamidine and Hexamidine Diisethionate2
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics2
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics2
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study2
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes2
Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model2
Comments on the Risks From Exposure to Denatonium Benzoate (Bitrex®): Denatured Alcohol Disinfection and Pandemic Times2
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™2
An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles—Nonclinical Considerations2
Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmetics2
Isobutane, Isopentane, Butane, and Propane2
A Review of the Main Considerations for Formulation Development in Preclinical Toxicology Studies2
Safety Evaluation of KP-10 (Metastin 45–54) Following once Daily Intravenous Administration for 14 Days in Dog2
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