International Journal of Toxicology

Papers
(The TQCC of International Journal of Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Development and Regulatory Challenges for Peptide Therapeutics18
Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors17
Tumor-Inhibitory Effects of Zerumbone Against HT-29 Human Colorectal Cancer Cells16
Exposure and Public Health Effects of Polycyclic Aromatic Hydrocarbon Compounds in Sub-Saharan Africa: A Systematic Review15
Safety Assessment of Silk Protein Ingredients as Used in Cosmetics15
Metabolomics as a Truly Translational Tool for Precision Medicine15
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™13
α-Melanocyte-Stimulating Hormone Triggers Melanogenesis Via Activation of the Aryl Hydrocarbon Receptor Pathway in B16F10 Mouse Melanoma Cells11
Exploring Potential Carcinogenic Activity of Per- and Polyfluorinated Alkyl Substances Utilizing High-Throughput Toxicity Screening Data9
Safety Assessment of Polyaminopropyl Biguanide (Polyhexamethylene Biguanide Hydrochloride) as Used in Cosmetics8
Evaluation of Pulmonary Effects of 3-D Printer Emissions From Acrylonitrile Butadiene Styrene Using an Air-Liquid Interface Model of Primary Normal Human-Derived Bronchial Epithelial Cells8
Liquiritigenin Blocks Breast Cancer Progression by Inhibiting Connective Tissue Growth Factor Expression via Up-Regulating miR-383-5p8
Toxicology Practice During COVID-19 Pandemic: Experience of the Dammam Poison Control Center-Eastern Province, Saudi Arabia8
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex7
Amended Safety Assessment of Methylchloroisothiazolinone and Methylisothiazolinone as Used in Cosmetics7
Safety Assessment of AAV2-hGDNF Administered Via Intracerebral Injection in Rats for Treatment of Parkinson's Disease6
Safety Assessment of Monoglyceryl Monoesters as Used in Cosmetics6
Genotoxicity of Glyphosate on Cultured Human Lymphocytes6
Nonclinical Safety Profile of Sotorasib, a KRASG12C-Specific Covalent Inhibitor for the Treatment of KRAS p.G12C-Mutated Cancer6
Evaluation of the Effect of Hyaluronic Acid–Based Biomaterial Enriched With Tenascin-C on the Behavior of the Neural Stem Cells6
Survivin Promoter-Driven DFF40 Gene Expression Sensitizes Melanoma Cancer Cells to Chemotherapy6
Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database6
Drug-Induced Seizures: Considerations for Underlying Molecular Mechanisms6
Combined Cardiopulmonary Assessments Using Impedance and Digital Implants in Conscious Freely Moving Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs: Pharmacological Characterization and Socia6
Safety Assessment of L-β-Aminoisobutyric Acid (L-BAIBA): Subchronic Toxicity Study in Sprague Dawley Rats6
Effects of Chronic Exposure to Microcystin-LR on the Gut Microbiota of Male Mice6
Safety Assessment of Ceramides as Used in Cosmetics5
Repeated Dose Toxicity Study and Developmental and Reproductive Toxicology Studies of a Respiratory Syncytial Virus Candidate Vaccine in Rabbits and Rats5
Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease5
Safety Assessment of Saccharide Esters as Used in Cosmetics5
Influences of Unmodified and Carboxylated Carbon Nanotubes on Lipid Profiles in THP-1 Macrophages: A Lipidomics Study5
Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics5
Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison5
Four-Week Repeated Intravenous Dose Toxicity of Self-Assembled-Micelle Inhibitory RNA-Targeting Amphiregulin in Mice5
miR-185-5p Represses Cells Growth and Metastasis of Osteosarcoma via Targeting Cathepsin E5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats5
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species5
Protein-Ligand Identification and In Vitro Inhibitory Effects of Cathine on 11 Major Human Drug Metabolizing Cytochrome P450s5
The Utility of Novel Urinary Biomarkers in Mice for Drug Development Studies5
Effects of Vanadium Inhalation and Sweetened Beverage Ingestion in Mice: Morphological and Biochemical Changes in the Liver4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines4
Evaluation of Novel Urinary Biomarkers in Beagle Dogs With Amphotericin B-Induced Kidney Injury4
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics4
Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits4
Behavioral, Histopathologic, and Molecular Biological Responses of Nanoparticle- and Solution-Based Formulations of Vincristine in Mice4
Wood Smoke Extract Promotes Extracellular Matrix Remodeling in Normal Human Lung Fibroblasts4
Recent Advances in Drug Discovery Toxicology4
Using Evidence Integration Techniques in the Development of Health-Based Occupational Exposure Levels4
Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin4
Comparison of Illicit Drug Seizures Products of Natural Origin Using a Molecular Networking Approach4
Practical Considerations in Determining Adversity and the No-Observed-Adverse-Effect-Level (NOAEL) in Nonclinical Safety Studies: Challenges, Perspectives and Case Studies4
NEW: Haschek and Rousseaux’s Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology, 4th Edition - 20214
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics3
Proposal to Eliminate Urethane-Treated Positive Control Dose Groups in 26-Week Tg.rasH2 Carcinogenicity Studies3
Tumorigenicity Assessment of Human Cancer Cell Lines Xenografted on Immunodeficient Mice as Positive Controls of Tumorigenicity Testing3
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury3
Safety Assessment of Plant-Derived Proteins and Peptides as Used in Cosmetics3
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam3
Safety Assessment of Polyfluorinated Polymers as Used in Cosmetics3
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations3
Deriving Compound-Specific Exposure Limits for Chemicals Used in Pharmaceutical Synthesis: Challenges in Expert Decision-Making Exemplified Through a Case Study-Based Workshop3
Safety Assessment of Phosphoric Acid and Its Salts as Used in Cosmetics3
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics3
Amended Safety Assessment of Methylisothiazolinone as Used in Cosmetics3
Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use3
Small RNA Sequencing to Discover Circulating MicroRNA Biomarkers of Testicular Toxicity in Dogs2
MicroRNA-9-5p Is Involved in Lipopolysaccharide-Induced Acute Lung Injury Via the Regulation of Macrophage Polarization2
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive2
Transcription Factor E2F8 Promotes Cisplatin Resistance in Hepatocellular Carcinoma by Regulating DNA Damage via NUSAP12
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey2
Amended Safety Assessment of Malic Acid and Sodium Malate as Used in Cosmetics2
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics2
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue2
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro2
Application of the Key Characteristics of Carcinogens to Bisphenol A2
Evaluation of the AV7909 Anthrax Vaccine Toxicity in Sprague Dawley Rats Following Three Intramuscular Administrations2
Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Current Trends of Practices in Nonclinical Toxicology: An Industry Survey2
Safety Assessment of Citrus Peel-Derived Ingredients as Used in Cosmetics2
Palmitoylethanolamide: Prenatal Developmental Toxicity Study in Rats2
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics2
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics2
Evidence for Hesperidin as an Effective Factor in Initiating the Intrinsic Pathway of Apoptosis in KG1a Leukemia Cells2
Safety Assessment of Inorganic Hydroxides as Used in Cosmetics2
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Expression of Cytochrome P450 Enzymes in Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas: Possible Role in Carcinogenesis and Treatment Response2
Final Amended Safety Assessment of Sodium Sulfate as Used in Cosmetics2
Quantitative Risk Assessment of Dermal Sensitization Potential Following Use of Shampoo Products Containing the Formaldehyde Releasing Preservative DMDM Hydantoin2
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii2
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate2
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