International Journal of Toxicology

Papers
(The TQCC of International Journal of Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro21
Mink Oil16
Effect of Chronic Consumption of Fluoridated Water on Sciatic Nerve Conduction Velocity in Male Wistar Rats14
In Utero Exposure to Di-n-butyl Phthalate Causes Modulation in Neurotransmitter System of Wistar Rats: A Multigenerational Assessment13
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats11
Safety Assessment of Adenosine as Used in Cosmetics11
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations10
I Wish I Had Known That! Impactful Guidance and Perspectives for a Fulfilling Career in Toxicology10
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics10
A Characterization of the Nonclinical Pharmacology and Toxicology of Aficamten, a Reversible Allosteric Inhibitor of Cardiac Myosin10
Sodium α-Olefin Sulfonates10
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics10
Isopropyl Lanolate10
Amended Safety Assessment of Synthetically Manufactured Amorphous Silica and Hydrated Silica as Used in Cosmetics9
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics9
Glycol Stearate and Glycol Stearate SE9
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review8
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development8
Editor’s Note8
Microplastics: A Narrative Review on Modes of Exposure and Impact on Human Health8
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients7
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics7
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics7
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics7
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity7
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate6
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii6
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics6
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice6
Polyamino Sugar Condensate6
A Commentary on Fasting of Nonclinical Research Animals6
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species6
Amyl Acetate and Isoamyl Acetate6
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration5
Book Review: Reproductive and Developmental Toxicology Third Edition5
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam5
Lard and Lard-Derived Ingredients5
Toxicology Certification: The Need, the Value, and an Evolving Landscape5
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey5
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats4
Incidence of Neoplasms and Selected Non-Neoplastic Findings in Control and Positive Control Groups in CByB6F1-Tg(HRAS)2Jic Hemizygous (rasH2 TM ) Mouse Carcinogenici4
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review4
Thank you to our ad hoc reviewers!4
Safety Assessment of Methylxanthines as Used in Cosmetics4
Effects of Solvent Dimethyl Sulfoxide Invites a Rethink of Its Application in Amyloid Beta Cytotoxicity4
Predictive Modeling of Pharmacokinetic Drug–Drug and Herb–Drug Interactions in Oncology: Insights From PBPK Studies4
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex4
Comparative Analyses of the Influences of Vehicles on Selected Biological Parameters Following Single-Dose Oral Administration in Sprague-Dawley Rats4
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines4
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics3
Re-Review Summary of PEG Stearates as Used in Cosmetics3
Book Review: Haschek and Rousseaux’s Handbook of Toxicologic Pathology3
Mitochondria: Key Mediator for Environmental Toxicant–Induced Neurodegeneration3
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models3
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples3
Book Reviews3
Safety Assessment of Alkyl Amide MIPA Ingredients as Used in Cosmetics3
Safety Assessment of Carica papaya (Papaya)—Derived Ingredients as Used in Cosmetics3
Book Review: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals3
Exploring the Biological Effects of Polystyrene Nanoplastics on Spermatogenesis: Insights From Transcriptomic Analysis in Mouse Spermatocytes3
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue3
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics3
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study3
Are Repeat-Dose Toxicity Studies Informative for Safety Assessment of Vaccine Candidates? A Survey of Vaccine Developers3
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System3
Re-Review Summary of VA/Crotonates Copolymer as Used in Cosmetics3
Quaternium-18 and Quaternium-18 Bentonite3
Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics3
Eleventh Triennial Toxicology Salary Survey2
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,2
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys (Macaca mulatta)2
Isobutane, Isopentane, Butane, and Propane2
Hexamidine and Hexamidine Diisethionate2
Editor’s note2
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™2
Safety Assessment of Polyquaternium-6 as Used in Cosmetics2
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations2
Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics2
Editor’s note2
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive2
Biotin2
Re-Review Summary of Sodium Sesquicarbonate, Sodium Carbonate, and Sodium Bicarbonate as Used in Cosmetics2
An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles—Nonclinical Considerations2
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics2
The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients—The Putative Mechanism Behind ILD2
Recent Advances in Drug Discovery Toxicology2
Safety Assessment of Scutellaria baicalensis -Derived Ingredients as Used in Cosmetics2
Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics2
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent2
Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model2
Methylglyoxal Aggregates α-Synuclein by Inhibiting SIRT1-Hif-1α in Intestinal Enteroendocrine Cells2
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics2
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research2
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes2
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics2
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury2
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate2
Safety Assessment of Basic Yellow 57 as Used in Cosmetics2
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