OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Toxicology is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-09-01 to 2024-09-01.)

Article	Citations
Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors	17
Development and Regulatory Challenges for Peptide Therapeutics	17
Safety Assessment of Silk Protein Ingredients as Used in Cosmetics	15
Tumor-Inhibitory Effects of Zerumbone Against HT-29 Human Colorectal Cancer Cells	15
Metabolomics as a Truly Translational Tool for Precision Medicine	14
Effects of Reverse Transcriptase Inhibitors on Proliferation, Apoptosis, and Migration in Breast Carcinoma Cells	14
Exposure and Public Health Effects of Polycyclic Aromatic Hydrocarbon Compounds in Sub-Saharan Africa: A Systematic Review	13
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™	12
Safety Assessment of Lecithin and Other Phosphoglycerides as Used in Cosmetics	11
Safety Assessment of PEGylated Alkyl Glycerides as Used in Cosmetics	10
α-Melanocyte-Stimulating Hormone Triggers Melanogenesis Via Activation of the Aryl Hydrocarbon Receptor Pathway in B16F10 Mouse Melanoma Cells	10
Exploring Potential Carcinogenic Activity of Per- and Polyfluorinated Alkyl Substances Utilizing High-Throughput Toxicity Screening Data	9
Toxicology Practice During COVID-19 Pandemic: Experience of the Dammam Poison Control Center-Eastern Province, Saudi Arabia	8
Safety Assessment of Polyaminopropyl Biguanide (Polyhexamethylene Biguanide Hydrochloride) as Used in Cosmetics	8
Evaluation of Pulmonary Effects of 3-D Printer Emissions From Acrylonitrile Butadiene Styrene Using an Air-Liquid Interface Model of Primary Normal Human-Derived Bronchial Epithelial Cells	8
Liquiritigenin Blocks Breast Cancer Progression by Inhibiting Connective Tissue Growth Factor Expression via Up-Regulating miR-383-5p	8
Amended Safety Assessment of Methylchloroisothiazolinone and Methylisothiazolinone as Used in Cosmetics	7
Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex	7
Combined Cardiopulmonary Assessments Using Impedance and Digital Implants in Conscious Freely Moving Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs: Pharmacological Characterization and Socia	6
Safety Assessment of AAV2-hGDNF Administered Via Intracerebral Injection in Rats for Treatment of Parkinson's Disease	6
Safety Assessment of Monoglyceryl Monoesters as Used in Cosmetics	6
Evaluation of the Effect of Hyaluronic Acid–Based Biomaterial Enriched With Tenascin-C on the Behavior of the Neural Stem Cells	6
Nonclinical Safety Profile of Sotorasib, a KRAS^G12C-Specific Covalent Inhibitor for the Treatment of KRAS p.G12C-Mutated Cancer	6
Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species	5
Drug-Induced Seizures: Considerations for Underlying Molecular Mechanisms	5

Four-Week Repeated Intravenous Dose Toxicity of Self-Assembled-Micelle Inhibitory RNA-Targeting Amphiregulin in Mice	5
Safety Assessment of Ceramides as Used in Cosmetics	5
Nonclinical Safety Assessment of Lipid Nanoparticle-and Emulsion-Based Self-Amplifying mRNA Vaccines in Rats	5
Safety Assessment of L-β-Aminoisobutyric Acid (L-BAIBA): Subchronic Toxicity Study in Sprague Dawley Rats	5
Evaluation of the Expression Profile of Antibiotic-Induced Thrombocytopenia Using the Japanese Adverse Drug Event Report Database	5
The Utility of Novel Urinary Biomarkers in Mice for Drug Development Studies	5
Influences of Unmodified and Carboxylated Carbon Nanotubes on Lipid Profiles in THP-1 Macrophages: A Lipidomics Study	5
Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics	5
Effects of Chronic Exposure to Microcystin-LR on the Gut Microbiota of Male Mice	5
Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease	5
Survivin Promoter-Driven DFF40 Gene Expression Sensitizes Melanoma Cancer Cells to Chemotherapy	5
miR-185-5p Represses Cells Growth and Metastasis of Osteosarcoma via Targeting Cathepsin E	5
Repeated Dose Toxicity Study and Developmental and Reproductive Toxicology Studies of a Respiratory Syncytial Virus Candidate Vaccine in Rabbits and Rats	5
Effects of Vanadium Inhalation and Sweetened Beverage Ingestion in Mice: Morphological and Biochemical Changes in the Liver	4
Wood Smoke Extract Promotes Extracellular Matrix Remodeling in Normal Human Lung Fibroblasts	4
Genotoxicity of Glyphosate on Cultured Human Lymphocytes	4
Practical Considerations in Determining Adversity and the No-Observed-Adverse-Effect-Level (NOAEL) in Nonclinical Safety Studies: Challenges, Perspectives and Case Studies	4
Confounders and Pharmacological Characterization When Using the QT, JTp, and Tpe Intervals in Beagle Dogs	4
Safety Assessment of Saccharide Esters as Used in Cosmetics	4
Assessment of Statin Interactions With the Human NTCP Transporter Using a Novel Fluorescence Assay	4
Evaluation of Novel Urinary Biomarkers in Beagle Dogs With Amphotericin B-Induced Kidney Injury	4
NEW: Haschek and Rousseaux’s Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology, 4th Edition - 2021	4
Using Evidence Integration Techniques in the Development of Health-Based Occupational Exposure Levels	4
Behavioral, Histopathologic, and Molecular Biological Responses of Nanoparticle- and Solution-Based Formulations of Vincristine in Mice	4
Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines	4
Comparison of Illicit Drug Seizures Products of Natural Origin Using a Molecular Networking Approach	4
Recent Advances in Drug Discovery Toxicology	4
Protein-Ligand Identification andIn VitroInhibitory Effects of Cathine on 11 Major Human Drug Metabolizing Cytochrome P450s	4
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics	4
Tumorigenicity Assessment of Human Cancer Cell Lines Xenografted on Immunodeficient Mice as Positive Controls of Tumorigenicity Testing	3
Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits	3
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics	3
Safety Assessment of Plant-Derived Proteins and Peptides as Used in Cosmetics	3
Proposal to Eliminate Urethane-Treated Positive Control Dose Groups in 26-Week Tg.rasH2 Carcinogenicity Studies	3
Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations	3
Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use	3
Deriving Compound-Specific Exposure Limits for Chemicals Used in Pharmaceutical Synthesis: Challenges in Expert Decision-Making Exemplified Through a Case Study-Based Workshop	3
Safety Assessment of Phosphoric Acid and Its Salts as Used in Cosmetics	3
Amended Safety Assessment of Methylisothiazolinone as Used in Cosmetics	3
Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison	3
Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin	3
Assessment of Global DNA Methylation in SH-SY5Y Cells Exposed to the Neonicotinoid Insecticides Imidacloprid and Thiamethoxam	3
Evidence for Hesperidin as an Effective Factor in Initiating the Intrinsic Pathway of Apoptosis in KG1a Leukemia Cells	2
Final Amended Safety Assessment of Sodium Sulfate as Used in Cosmetics	2
Expression of Cytochrome P450 Enzymes in Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas: Possible Role in Carcinogenesis and Treatment Response	2
MicroRNA-9-5p Is Involved in Lipopolysaccharide-Induced Acute Lung Injury Via the Regulation of Macrophage Polarization	2
Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent	2
Safety Assessment of Polyfluorinated Polymers as Used in Cosmetics	2
Safety Assessment of Eucalyptus globulus (Eucalyptus)-Derived Ingredients as Used in Cosmetics	2
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate	2

Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics	2
Evaluation of the AV7909 Anthrax Vaccine Toxicity in Sprague Dawley Rats Following Three Intramuscular Administrations	2
Safety Assessment of Inorganic Hydroxides as Used in Cosmetics	2
Non-Human Primate Husbandry and Impact on Non-Human Primates Health: Outcomes From an IQ DruSafe/3RS Industrial Benchmark Survey	2
Application of the Key Characteristics of Carcinogens to Bisphenol A	2
Dose Range-Finding Toxicity Study in Rats With Recombinant Human Lactoferrin Produced in Komagataella phaffii	2
Safety Assessment of Apple-Derived Ingredients as Used in Cosmetics	2
Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics	2
Isoflurane Promotes Cell Proliferation, Invasion, and Migration by Regulating BACH1 and miR-375 in Prostate Cancer Cells In Vitro	2
Safety Assessment of Polyene Group as Used in Cosmetics	2
Safety Assessment of Citrus Peel-Derived Ingredients as Used in Cosmetics	2
Current Trends of Practices in Nonclinical Toxicology: An Industry Survey	2
Quantitative Risk Assessment of Dermal Sensitization Potential Following Use of Shampoo Products Containing the Formaldehyde Releasing Preservative DMDM Hydantoin	2
Amended Safety Assessment of Malic Acid and Sodium Malate as Used in Cosmetics	2
Palmitoylethanolamide: Prenatal Developmental Toxicity Study in Rats	2
Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury	2
Small RNA Sequencing to Discover Circulating MicroRNA Biomarkers of Testicular Toxicity in Dogs	2
The Non-Human Primate in Safety Assessment of a Bifunctional Long-Acting Insulin Analogue	2
Transcription Factor E2F8 Promotes Cisplatin Resistance in Hepatocellular Carcinoma by Regulating DNA Damage via NUSAP1	1
Recent Advances in Analytical Techniques for Antidepressants Determination in Complex Biological Matrices: A Review	1
Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review	1
Genetic Toxicity Studies of the Ketogenic Ester Bis Hexanoyl (R)-1,3-Butanediol	1
Investigational New Drug Enabling Nonclinical Safety Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent	1
Safety Assessment of Soy Proteins and Peptides as Used in Cosmetics	1
Lard and Lard-Derived Ingredients	1
Triacetin	1
Safety Assessment of Carbonate Salts as Used in Cosmetics	1
Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides as Used in Cosmetics	1
Safety Assessment ofHelianthus annuus(Sunflower)-Derived Ingredients as Used in Cosmetics	1
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development	1
Non-Clinical Cell Therapy Development Using the NCG Mouse Model as a Test System	1
Preclinical In-Vivo Safety of a Novel Thyrotropin-Releasing Hormone-Loaded Biodegradable Nanoparticles After Intranasal Administration in Rats and Primates	1
Alterations of Systemic and Hepatic Metabolic Function Following Exposure to Trans-nonachlor in Low and High Fat Diet Fed Male Sprague Dawley Rats	1
Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Exacerbates Methamphetamine-Induced Activation of Microglia and Neuroinflammation	1
Amended Safety Assessment of Butyl Polyoxyalkylene Ethers as Used in Cosmetics	1
Evaluation of Pharmaceuticals for DNA Damage in the Chicken Egg Genotoxicity Assay (CEGA)	1
Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model	1
Toxicological Implications of Biological Heterogeneity	1
Safety Evaluation of a Prototypical Diazirine-Based Covalent Crosslinker and Molecular Adhesive	1
Toxicological Assessment of Higher Olefins in OECD TG 422 Repeated Dose and Reproductive /Developmental Toxicity Screening Tests in Han Wistar Rats	1
AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration	1
Book Review: Handbook of Toxicology of Chemical Warfare Agents Third Edition	1
Nonclinical Testing Evaluation of Liposomes as Drug Delivery Systems	1
Safety Assessment of Ethers and Esters of Ascorbic Acid as Used in Cosmetics	1
Model Characterization: Total Body Irradiation or Busulfan for Conditioning in Human Cell Therapy Toxicology and Tumorigenicity Studies using NOD/SCID/IL2Rγnull (NSG) Mice	1
NRX-101, a Rapid-Acting Anti-Depressant, Does Not Cause Neurotoxicity Following Ketamine Administration in Preclinical Models	1
Glycol Stearate and Glycol Stearate SE	1
Amended Safety Assessment of Fatty Acyl Sarcosines and Sarcosinate Salts as Used in Cosmetics	1
Juvenile Bone Toxicity: Study Considerations, Regulations, and Techniques for Assessment	1
Imidazolidinyl Urea	1
Safety Evaluation of KP-10 (Metastin 45–54) Following once Daily Intravenous Administration for 14 Days in Dog	1
Book Review: Drug Safety Evaluation, Fourth Edition	1
Cottonseed Glyceride and Hydrogenated Cottonseed Glyceride	1
Regulatory Experience Assessing the Carcinogenic Potential of a Monoclonal Antibody Inhibiting PCSK9, Bococizumab, Including a 2-Year Carcinogenicity Study in Rats	1
Normal Neurodevelopment and Fertility in Juvenile Male Rats Exposed to Polyethylene Glycol Following Dosing With PEGylated rFIX (Nonacog Beta Pegol, N9-GP): Evidence from a 10-Week Repeat-Dose Toxicit	1
Safety Assessment of Rosa canina-derived Ingredients as Used in Cosmetics	1
Assessment of the Carcinogenic Potential of Pretomanid in Transgenic Tg.rasH2 Mice	1
Safety Assessment of Bovine Milk Proteins and Protein Derivatives as Used in Cosmetics	1
Managing COVID-19 Lockdown Impacts: Sustaining GLP Compliance and Man Material Medium (MMM) Strategy for Augmenting Prevention of Workplace Infections	1
A Review of the Main Considerations for Formulation Development in Preclinical Toxicology Studies	1
Peanut Glycerides	1
Novel Finding of Urinary Erythropoietin as an Early Biomarker of Cisplatin-Induced Nephrotoxicity	1
Co-Culturing Rat Dorsal Root Ganglion Neurons With Rat Schwann Cells Protects Them Against the Cytotoxic Effects of Silver and Gold Nanoparticles	1
Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmetics	1
Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats	1
Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics	1
A Health Intersection of Toxicology and Clinical Medicine	0
In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations	0
Polyacrylamide	0
Amended Safety Assessment of Triglycerides as Used in Cosmetics	0
Safety Assessment of Polysilicone-11 as Used in Cosmetics	0
In Vitro Evaluation of Vancomycin-Induced Toxicity in Human Primary Knee Chondrocytes	0
Safety Assessment of Butyrospermum parkii (Shea)-Derived Ingredients as Used in Cosmetics	0
Book Review: Reproductive and Developmental Toxicology Third Edition	0
In vitro Safety Assessment of Extracts and Compounds From Plants as Sunscreen Ingredients	0
Erythorbic Acid and Sodium Erythorbate	0
Exploring Greater Flexibility for Chronic Toxicity Study Designs to Support Human Safety Assessment While Balancing 3Rs Considerations	0
2020 ACT Annual Meeting Poster Abstracts	0
Phytantriol	0
Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity, Drug Abuse Liability, and Pediatric Safety	0

Comments on the Risks From Exposure to Denatonium Benzoate (Bitrex^®): Denatured Alcohol Disinfection and Pandemic Times	0
5-Lipoxygenase Contributes to Benzo[a]pyrene-Induced Cytotoxicity and DNA Damage in Human Bronchial Epithelial Cells	0
Eleventh Triennial Toxicology Salary Survey	0
Mitochondrial Impact of Organophosphate Pesticide-Induced Cardiotoxicity: An In Silico and In Vitro Study	0
Thank you to our ad hoc reviewers!	0
Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics	0
Safety Assessment of Vinylpyrrolidone Polymers as Used in Cosmetics	0
Editor’s Response to Jorge A. García-Valenzuela and Martha R. Baez-Gaxiola	0
Methyl Alcohol	0
Book Review: Information Resources in Toxicology	0
American College of Toxicology	0
Mutagenicity Assessment of Homologous Series of Methyl Ester Sulphonates (MES) Using the Bacterial Reverse Mutation (Ames) Test	0
Sodium Naphthalenesulfonate and Sodium Polynaphthalenesulfonate	0
PPG-11 and PPG-15 Stearyl Ether	0
Sodium Dehydroacetate and Dehydroacetic Acid	0
Temperature Is a Key Factor Governing the Toxic Impact of Ultra-Violet Radiation-Emitting Nail Dryers When Used on Human Skin Cells	0
Editor’s Note	0
EDTA and Salts	0
Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951), a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor, in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study	0
Isobutane, Isopentane, Butane, and Propane	0
High-Throughput Drug Screen for Potential Combinations With Venetoclax Guides the Treatment of Transformed Follicular Lymphoma	0
Corrigendum to “Eleventh Triennial Toxicology Salary Survey”	0
Quaternium-26	0
Gene Expression and Pathway Analysis in Rat Brain and Liver After Exposure to Royal Demolition Explosive (Hexahydro-1,3,5-Trinitro-1,3,5-Triazine)	0
Hexamidine and Hexamidine Diisethionate	0
A Commentary on Fasting of Nonclinical Research Animals	0
Preclinical Safety Evaluation of Etripamil Nasal Spray in Cynomolgus Macaques (Macaca fascicularis) to Assess for Safety in Patients With Paroxysmal Supraventricular Tachycardia	0
Safety Assessment of Alkyl Sultaines as Used in Cosmetics	0
Editor’s note	0
Safety Assessment of Adenosine as Used in Cosmetics	0
Book Review: Drug Disposition and Pharmacokinetics: Principles and Applications for Medicine, Toxicology and Biotechnology	0
Comparative Analyses of Poly(ADP-Ribose) Polymerase Inhibitors	0
Mink Oil	0
A Proposal for New Strategies in Dose Selection for 26-Week Tg.Rash2 Carcinogenicity Studies	0
Editor’s note	0
Quaternium-18 and Quaternium-18 Bentonite	0
Distortion Product Otoacoustic Emission Test is Not the Test to Use in Nonclinical Safety Assessment	0
Editor’s Note	0
Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples	0
Corrigendum to “Safety Assessment of High-Purity, Synthetic Nicotinamide Riboside (NR-E) in a 90-Day Repeated Dose Oral Toxicity Study, With a 28-Day Recovery Arm”	0
13-Week Repeated Oral Toxicity and Toxicokinetic Studies of Rabeprazole Sodium and Sodium Bicarbonate Combination in Dogs	0
Telomere Length and Arsenic: Improving Animal Models of Toxicity by Choosing Mice With Shorter Telomeres	0
Safety Assessment of Palm-Derived Ingredients as Used in Cosmetics	0
Safety Assessment of Streptococcus salivarius UBSS-01 in Rats and Double-Blind Placebo-Controlled Study in Healthy Individuals	0
Safety Assessment of Alkane Diols as Used in Cosmetics	0
Safety Assessment of Polyol Phosphates as Used in Cosmetics	0
Glyceryl Diesters	0
Phosphatidylinositol 3-Kinase δ-Specific Inhibitor-Induced Changes in the Ovary and Testis in the Sprague Dawley Rat and Cynomolgus Monkey	0
The Nonclinical Assessment of Trans-1,3,3,3-tetrafluoropropene (HFO-1234ze (E)), a Near Zero Global Warming Potential Propellant for Use in Metered Dose Inhalation Products	0
Chloroxylenol	0
Amended Safety Assessment of Mentha piperita (Peppermint)–Derived Ingredients as Used in Cosmetics	0
Safety Assessment of Triphenyl Phosphate as Used in Cosmetics	0
Toxicology Certification: The Need, the Value, and an Evolving Landscape	0
Hepatitis A Virus Infection in Cynomolgus Monkeys Confounds the Safety Evaluation of a Drug Candidate	0
Thank You to Our Ad Hoc Reviewers!	0
Pharmaceutical Industry Perspective on the Non-Clinical Evaluation of Novel Excipients: Results From an Industry Survey Conducted by the IQ Novel Excipient Working Group	0
Electrophysiological Changes in the Rabbit Ventricular Wedge and Human-Induced Pluripotent Stem-Cell Derived (IPSC) Cardiomyocytes Translate to Severe Arrhythmia Observed in a Canine Toxicology Study,	0
Safety Assessment of Cocos nucifera (Coconut)-Derived Ingredients as Used in Cosmetics	0
Corrigendum to “Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside–β-Cyclodextrin Inclusion Complex”	0
Polyamino Sugar Condensate	0
Amended Safety Assessment of Persulfates as Used in Cosmetics	0
Glyoxal	0
The Spontaneous Incidence of Neurological Clinical Signs in Preclinical Species Using Cage-side Observations or High-definition Video Monitoring: A Retrospective Analysis	0
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats	0
Editor’s note	0
Book Reviews: The Coronavirus Pandemic and the Future Volume 1 and Volume 2: Virology, Epidemiology, Translational Toxicology and Therapeutics	0
Assessing the Safety of MA-[D-Leu-4]-OB3, a Synthetic Peptide Leptin Mimetic: Two Pre-Clinical Toxicity Studies in Male and Female C57BL/6 Mice	0
An Overview of Gene Editing Modalities and Related Non-clinical Testing Considerations	0
Book Review: Organ-on-a-Chip Engineered Microenvironments for Safety and Efficacy Testing	0
Isopropyl Lanolate	0
Harihara M. Mehendale: A Life Dedicated to Mentoring and Research	0
Amended Safety Assessment of Acid Violet 43 as Used in Cosmetics	0
Aluminum Starch Octenylsuccinate	0
Corrigendum to: “Toxicology Certification: The Need, the Value, and an Evolving Landscape”	0
ACT 2021 Virtual Annual Meeting Poster Abstracts	0
So…….You Want to be a Peer Reviewer?	0
Safety Assessment of Hydrogen Peroxide as Used in Cosmetics	0
Zinc Phenolsulfonate	0
Updating the Standards of Professional Competence in the Field of Toxicology: The Second Generation of Best Practice	0
Dioscorea Villosa (Wild Yam) Root Extract	0
Thank You to Our Ad Hoc Reviewers!	0
Preclinical Safety Evaluation of the Human-Identical Milk Oligosaccharide Lacto-N-Triose II	0
Copper Chaperone Atox1 Protected the Cochlea From Cisplatin by Regulating the Copper Transport Family and Cell Cycle	0
Squalane and Squalene	0
HC Yellow 5	0
A Review of Hydrotropic Solubilization Techniques for Enhancing the Bioavailability of Poorly Soluble Drugs	0
Putting a Face on Research	0
Safety Assessment of Hops as Used in Cosmetics	0
Sodium α-Olefin Sulfonates	0
Book Reviews	0
Safety Assessment of Methylxanthines as Used in Cosmetics	0
Editor’s Note	0
Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmetics	0
Amyl Acetate and Isoamyl Acetate	0
Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics	0