OOIR: Observatory of International Research

Papers

(The TQCC of Nitric Oxide-Biology and Chemistry is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Nitric oxide and tumor necrosis factor-⍺ levels are negatively correlated in endotoxin tolerance recovery in vitro	79
Editorial Board	70
Compartment-specific nitric oxide signaling in mouse cardiac endothelial cells: Intra- and extracellular measurements and the impact of cryopreservation	67
The effect of nitroglycerin treatment on cerebral ischaemia: A systematic review and meta-analysis of animal studies	67
ENDOGENOUS CYANIDE REGULATES THE FUNCTION OF ENDOTHELIAL CELLS	61
The role of H2S in isoproterenol-induced cardiac hypertrophy	48
Hydrogen Sulfide differentially shapes glial polarization	41
Hydrogen sulfide biology comes of age: Perspectives from the 8th International Conference on H2S in biology and medicine	34
Protective effects of hydrogen sulfide pretreatment on cyclophosphamide-induced bladder dysfunction in rats via suppression of bladder afferent nerves	32
Are salivary NO2− / NO2− and NO3− levels biomarkers for dental caries in children? Systematic review and meta-analysis	30
Editorial Board	30
The role of nitric oxide (NO) modulators in obsessive-compulsive disorder (OCD)	27
Corrigendum to “Cannabidiol induces systemic analgesia through activation of the PI3Kγ/ nNOS/NO/KATP signaling pathway in neuropathic mice. A KATP channel S-nitrosylation-dependent mechanism” [Nitric	26
Critical role of hydrogen sulfide in the management of neurodegenerative disease	26
Generation of high-concentration medical-grade nitric oxide via air-sourced pulsed arc discharge	26
Salvia Miltiorrhiza Derived Natural Compounds are Potent Inhibitors of 3-MERCAPTOPYRUVATE SULFURTRANSFERASE	25
Cysteine 317 as a potential regulatory site in Glucose-6-phosphate dehydrogenase (G6PDH) in Saccharomyces cerevisiae.	25
Protective effect of hydrogen-sulfide donors in preventing diabetic liver damage via ferroptosis inhibition in C57/BL6 mice	25
Application of hydrogen sulfide donor conjugates in different diseases	24
Roles of nitric oxide in improving post-harvest horticultural product quality: Crosstalk with hydrogen sulfide	23
Nitric oxide functional relationships with nitrogen-containing stress metabolites: Role in plant adaptation to adverse abiotic factors	23
Comparing in vitro nitric oxide blood uptake to its pulmonary diffusing capacity	22
Hydrogen sulfide potently promotes neuronal differentiation of adipose tissue-derived stem cells involving nitric oxide-mediated signaling cascade with the aid of cAMP-elevating agents	21
Editorial Board	21
Detection and proteomic identification of in vivo S-nitrosylated proteins in Vibrio cholerae: A novel evidence	20

Impact of nitric oxide in liver cancer microenvironment	19
Synthesis and secretion of Nerve Growth Factor is regulated by Nitric Oxide in bladder cells in vitro under a hyperglycemic environment	19
High Resolution Flow System for Quantifying the Time- and Concentration- Dependent Effects of H2S on Cell and Tissue Function.	19
Corrigendum to “Effects of dietary nitrate supplementation on peak power output: Influence of supplementation strategy and population” [Nitric Oxide 136-137C (2023) 33–47]	19
Cell-specific effects of 3-mercaptopyruvate sulfurtransferase in obesity	18
Numerical study on the distribution of nitric oxide concentration in the nasal cavity of healthy people during breathing	18
Spraying with encapsulated nitric oxide donor reduces weight loss and oxidative damage in papaya fruit	17
Effects of low doses of different nitric oxide (NO) donors in rat models of obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD)	16
Editorial Board	16
Diabetic peripheral neuropathy: Role of nitric oxide	16
Editorial Board	16
NO- and H2S- releasing nanomaterials: A crosstalk signaling pathway in cancer	16
Nitric oxide inhibits alginate biosynthesis in Pseudomonas aeruginosa and increases its sensitivity to tobramycin by downregulating algU gene expression	16
Editorial Board	16
Comprehensive evaluation of S-nitrosoglutathione and S-nitroso-N-acetylpenicillamine stability in biomedical contexts	16
Selective allosteric inhibition of cystathionine GAMMA-lyase as a broad anticancer strategy	15
A Novel H2S/NO Donor for INTRAOCULAR PRESSURE Reduction and Retinal Neuroprotection	15
Mapping hydrogen sulfide biosynthesis and oxidation pathways in placenta health and diseases: a scoping review	15
Fluorometric toolkit for methanethiol quantification and methanethiol oxidase activity determination in diverse biological systems	15
Butyrate inhibits LPC-induced endothelial dysfunction by regulating nNOS-produced NO and ROS production	14
Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice	14
Dimethylarginine Dimethylaminohydrolase - 1 expression is increased under tBHP-induced oxidative stress regulates nitric oxide production in PCa cells attenuates mitochondrial ROS-mediated apoptosis	13
Transdermal iontophoretic application of l-NAME is available in sweating research induced by heat stress in young healthy adults	13
Editorial Board	13
Editorial Board	13
MULTIMODAL ENVIRONMENTAL HYDROGEN SULFIDE EXPOSURE: A CONCEPTUAL FRAMEWORK LINKING EXOGENOUS SULFIDE DELIVERY TO REDOX SIGNALING IN BALNEOLOGY	12
Synthesis and nitroxyl (HNO) donating properties of benzoxadiazole-based Piloty's acids	12
Nitric oxide protects intestinal mucosal barrier function and prevents acute graft rejection after intestinal transplantation: A mini-review	12
Heterogenous improvements in endothelial function by sub-blood pressure lowering doses of ARBs result in major anti-aortic root remodeling effects	12
Phytochemicals targeting nitric oxide signaling in neurodegenerative diseases	12
SOLUBLE CD163 AS A BIOMARKER OF MACROPHAGE ACTIVATION IN OSTEOARTHRITIS: ASSOCIATION WITH HYDROGEN SULFIDE LEVELS	11
VISUALIZATION OF HYDROGEN SULFIDE IN ASTROCYTES THROUGH MOUSE CLOSED CRANIAL WINDOW WITH TWO PHOTON LASER MICROSCOPE	10
Divergent roles of endothelial and red blood cell nitric oxide synthase in regulating cardiovascular function during anemia	10
Nitric oxide: An emerging warrior of plant physiology under abiotic stress	10
Leveraging the redundancy of S-denitrosylases in response to S-nitrosylation of caspases: Experimental strategies and beyond	10
Involvement of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) levels in precancerous and cancerous cervical lesions	10
Regulation of molecular mechanisms by a pharmacological hydrogen sulfide donor targeting mitochondria in the regeneration of chronic gastric ulcers	10
Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes	10
Bystander effect in photosensitized prostate cancer cells with a different grade of malignancy: The role of nitric oxide	10
Editorial Board	9
Nitric oxide: A potential etiological agent for vaso-occlusive crises in sickle cell disease	9
Editorial Board	9
Editorial Board	9
Effect of nitrate supplementation on oxygen saturation levels for acute mountain sickness prevention: A systematic review and meta-analysis	9
Structure-activity relationship of S-adenosylmethionine analogs as pharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria	9
The role and mechanism of hydrogen sulfide in liver fibrosis	9
The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status	9
The Nitric Oxide Society and the Nitric Oxide Journal: Returning to our foundation to shape the future of redox biology	9
Investigating the effect of inhaled nitric oxide combined with prone position ventilation on ventilation/perfusion matching in patients with moderate-to-severe acute respiratory distress syndrome	9
Therapeutic potential of S-nitroso-l-cysteine in improving cardiorenal function in eNOS-KO CKD mice	9

Dose-Dependent Restoration of Aminoglycoside Activity by Exogenous Hydrogen Sulfide in Carbapenem-Resistant Pseudomonas aeruginosa	8
Nitric oxide mediated alleviation of abiotic challenges in plants	8
H2S–SYNTHESIZING ENZYMES may play a role IN Breast CANCER CHEMORESISTANCE	8
Development of nitric oxide generators to produce high-dose nitric oxide for inhalation therapy	8
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis	8
Nitric oxide as a mediator of exercise performance: NO pain NO gain	8
A systematic review and dose‒response meta-analysis of the association between nitrate & nitrite intake and gastroesophageal cancer risk	8
A Novel H2S-Releasing Ibuprofen Derivative (EV-34) with Special Release KineticS Mitigates Doxorubicin-Induced Cardiac Injury	8
H2S Drives Slow-Fiber Remodeling and Restores PGC-1α Signaling in Duchenne Muscular Dystrophy	8
Reduction in blood pressure following acute dietary nitrate ingestion is correlated with increased red blood cell S-nitrosothiol concentrations	8
An observational analysis on the influence of parental allergic rhinitis, asthma and smoking on exhaled nitric oxide in offspring	8
Say “NO” to plant stresses: Unravelling the role of nitric oxide under abiotic and biotic stress	8
A Resveratrol–hydrogen sulfide donor hybrid as a multi-target therapeutic strategy for allergic asthma	8
Structural basis for a filamentous morpheein model of human cystathionine beta-synthase	8
Editorial Board	7
Mechanisms Mediating Stimulatory Effects of Hydrogen Sulfide on Insulin Secretion in Pancreatic Islets	7
Nitric oxide synthase inhibitors as potential therapeutic agents for gliomas: A systematic review	7
Diabetic nephropathy: Role of nitric oxide	7
Strategies targeting the NO pathway to counteract extra-pulmonary manifestations of COPD: A systematic review and meta-analysis	7
Carbon monoxide as a negative feedback mechanism on HIF-1α in the progression of metabolic-associated fatty liver disease	7
Endogenous Cyanide Generation by Pseudomonas aeruginosa Suppresses the Host Immune Response	7
Dietary nitrate supplementation increases nitrate and nitrite concentrations in human skin interstitial fluid	7
Macrophages, IL-10, and nitric oxide increase, induced by hyperglycemic conditions, impact the development of murine melanoma B16F10-Nex2	7
ORCHESTRATING THE TRANSCRIPTIONAL COORDINATION OF H2S AND NITRIC OXIDE BIOSYNTHETIC PATHWAYS IN 3D COLORECTAL CANCER-RESISTANT MODELS UNDER 5-FLUOROURACIL STRESS	7
5-HT7 receptor antagonist SB269970 attenuates seizures by modulating NO/cGMP signaling pathway and neuroinflammation in a pentylenetetrazol-induced epilepsy model in rats	7
Inhaled nitric oxide improves post-cardiac arrest outcomes via guanylate cyclase-1 in bone marrow-derived cells	7