Nitric Oxide-Biology and Chemistry

Article	Citations
Tackle the free radicals damage in COVID-19	82
Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19	73
Insights into nitric oxide-mediated water balance, antioxidant defence and mineral homeostasis in rice (Oryza sativa L.) under chilling stress	59
Recent developments of fluorescent probes for detection and bioimaging of nitric oxide	53
The solution chemistry of nitric oxide and other reactive nitrogen species	48
Nitric oxide dosed in short bursts at high concentrations may protect against Covid 19	46
Construction of a nitro-oxidative stress-driven, mechanistic model of mood disorders: A nomothetic network approach	43
Role of neuronal nitric oxide synthase on cardiovascular functions in physiological and pathophysiological states	41
Implications of SARS-Cov-2 infection on eNOS and iNOS activity: Consequences for the respiratory and vascular systems	36
Isolation and culture of murine bone marrow-derived macrophages for nitric oxide and redox biology	35
Inhaled high dose nitric oxide is a safe and effective respiratory treatment in spontaneous breathing hospitalized patients with COVID-19 pneumonia	29
Nitric oxide protects against ferroptosis by aborting the lipid peroxidation chain reaction	28
Proteomic analysis reveals the protective role of exogenous hydrogen sulfide against salt stress in rice seedlings	28
Hydrogen sulfide signaling in regulation of cell behaviors	28
A brief history of carbon monoxide and its therapeutic origins	27
Interactive role of exogenous 24 Epibrassinolide and endogenous NO in Brassica juncea L. under salinity stress: Evidence for NR-dependent NO biosynthesis	27
Blood nitrate and nitrite modulating nitric oxide bioavailability: Potential therapeutic functions in COVID-19	26
Mechanisms of the protective effects of nitrate and nitrite in cardiovascular and metabolic diseases	25
A comparison of the chemical biology of hydropersulfides (RSSH) with other protective biological antioxidants and nucleophiles	25
Chitosan chemically modified to deliver nitric oxide with high antibacterial activity	22
Supplementation of dietary nitrate attenuated oxidative stress and endothelial dysfunction in diabetic vasculature through inhibition of NADPH oxidase	22
Methods in sulfide and persulfide research	21
Sprint and endurance training in relation to redox balance, inflammatory status and biomarkers of aging in master athletes	21
Nitric oxide: Clinical applications in critically ill patients	20
Time course of human skeletal muscle nitrate and nitrite concentration changes following dietary nitrate ingestion	20

Head-to-head comparison of inorganic nitrate and metformin in a mouse model of cardiometabolic disease	20
Changes of nNOS expression in the tuberal hypothalamic nuclei during ageing	18
Total body irradiation-induced colon damage is prevented by nitrate-mediated suppression of oxidative stress and homeostasis of the gut microbiome	17
Endocan alters nitric oxide production in endothelial cells by targeting AKT/eNOS and NFkB/iNOS signaling	17
Association between hypertension, oral microbiome and salivary nitric oxide: A case-control study	17
Say “NO” to plant stresses: Unravelling the role of nitric oxide under abiotic and biotic stress	16
Effect of inorganic nitrate supplementation on blood pressure in older adults: A systematic review and meta-analysis	16
Cellular microdomains for nitric oxide signaling in endothelium and red blood cells	16
Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes	15
Control of rat muscle nitrate levels after perturbation of steady state dietary nitrate intake	15
Light-induced nitric oxide release in the skin beyond UVA and blue light: Red & near-infrared wavelengths	14
Administration of H2S improves erectile dysfunction by inhibiting phenotypic modulation of corpus cavernosum smooth muscle in bilateral cavernous nerve injury rats	13
Maternal disease and gasotransmitters	13
Peroxynitrite is a novel risk factor and treatment target of glaucoma	12
Nitric-oxide releasing chitosan nanoparticles towards effective treatment of cutaneous leishmaniasis	12
Effects of nitrite and far-red light on coagulation	12
Fractional exhaled Nitric Oxide (FeNO) level as a predictor of COVID-19 disease severity	12
The effect of beetroot inorganic nitrate supplementation on cardiovascular risk factors: A systematic review and meta-regression of randomized controlled trials	12
Effect of inorganic nitrate on metabolic parameters in patients with type 2 diabetes: A 24-week randomized double-blind placebo-controlled clinical trial	12
Moving beyond inclusion: Methodological considerations for the menstrual cycle and menopause in research evaluating effects of dietary nitrate on vascular function	12
Using diaminofluoresceins (DAFs) in nitric oxide research	11
Buffer concentration dramatically affects the stability of S-nitrosothiols in aqueous solutions	11
Ideation and assessment of a nitric oxide delivery system for spontaneously breathing subjects	11
Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension	11
Lifestyle-mediated nitric oxide boost to prevent SARS-CoV-2 infection: A perspective	11
Phorbol myristate acetate induces differentiation of THP-1 cells in a nitric oxide-dependent manner	11
Acidified nitrite improves wound healing in type 2 diabetic rats: Role of oxidative stress and inflammation	11
Nitric oxide mediated alleviation of abiotic challenges in plants	11
Nitric oxide and skeletal muscle contractile function	10
Mechanisms of nitric oxide generation in living systems	10
Phytochemicals targeting nitric oxide signaling in neurodegenerative diseases	10
S-nitrosothiol-terminated poly(vinyl alcohol): Nitric oxide release and skin blood flow response	10
Renal nitrate clearance in chronic kidney disease	10
Prognostic value of asymmetric dimethylarginine in patients with coronary artery disease: A meta-analysis	9
Repeated but not acute exposure with a low dose range of the nitric oxide (NO) donor sodium nitroprusside (SNP) induces anxiolytic-like behaviour in a dose-independent manner in two different rat mode	9
Nitric oxide regulation of cellular metabolism: Adaptive tuning of cellular energy	9
Nitric oxide synthase inhibitor L-NG-nitroarginine methyl ester (L-NAME) attenuates remobilization-induced joint inflammation	9
Photobiomodulation and nitric oxide signaling	9
N-Nitrosomelatonin, an efficient nitric oxide donor and transporter in Arabidopsis seedlings	9
Rectal administration of carbon monoxide inhibits the development of intestinal inflammation and promotes intestinal wound healing via the activation of the Rho-kinase pathway in rats	9
Influence of muscle oxygenation and nitrate-rich beetroot juice supplementation on O2 uptake kinetics and exercise tolerance	9
Inorganic nitrate: A potential prebiotic for oral microbiota dysbiosis associated with type 2 diabetes	8
Estrogen receptor (ESR1 and ESR2)-mediated activation of eNOS–NO–cGMP pathway facilitates high altitude acclimatization	8
Valproic acid up-regulates the whole NO-citrulline cycle for potent iNOS-NO signaling to promote neuronal differentiation of adipose tissue-derived stem cells	8
The oral microbiome, nitric oxide and exercise performance	8
Real-time redox monitoring of a nitrosyl ruthenium complex acting as NO-donor agent in a single A549 cancer cell with multiplex Fourier-transform infrared microscopy	8
Recent advances in nanotherapeutic strategies that target nitric oxide pathway for preventing cartilage degeneration	8
Brain hydrogen sulfide suppresses the micturition reflex via brain GABA receptors in rats	8
A comparison of multifunctional donors of carbon monoxide: Their anticoagulant, antioxidant, anti-aggregatory and cytotoxicity activities in an in vitro model	8
Effects of resveratrol supplementation on nitric oxide-mediated vascular outcomes in hypertension: A systematic review	8

Blockade of nitric oxide signalling promotes resilience to the effects of social defeat stress on the conditioned rewarding properties of MDMA in mice	8
Photodissociation of nitric oxide from designed ruthenium nitrosyl complex: Studies on wound healing and antibacterial activity	7
Effects of albumin-bound nitrosyl iron complex with thiosulfate ligands on lipid peroxidation and activities of mitochondrial enzymes in vitro	7
Impact of nitric oxide in liver cancer microenvironment	7
Tri-iodide and vanadium chloride based chemiluminescent methods for quantification of nitrogen oxides	7
Reduced nitric oxide synthesis in winter: A potential contributing factor to increased cardiovascular risk	7
Nitric oxide bioavailability for red blood cell deformability in the microcirculation: A review of recent progress	7
Skeletal muscle as a reservoir for nitrate and nitrite: The role of xanthine oxidase reductase (XOR)	6
Beet on Alps: Time-course changes of plasma nitrate and nitrite concentrations during acclimatization to high-altitude	6
Dietary N-nitroso compounds intake and bladder cancer risk: A systematic review and meta-analysis	6
Electrophilic nitrated fatty acids are potential therapeutic candidates for inflammatory and fibrotic lung diseases	6
Cellular mechanisms underlying carbon monoxide stimulated anion secretion in rat epididymal epithelium	6
Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy	6
The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development	6
More questions than answers for the use of inhaled nitric oxide in COVID-19	6
Tobacco smoke exposure and fractional exhaled nitric oxide levels among U.S. adolescents	6
GAPDH S-nitrosation contributes to age-related sarcopenia through mediating apoptosis	6
Preserved activity of soluble guanylate cyclase (sGC) in iliac artery from middle-aged rats: Role of sGC modulators	6
“Removal of nitrate and nitrite by hemodialysis in end-stage renal disease and by sustained low-efficiency dialysis in acute kidney injury”	6
Inhaled nitric oxide in adults with in-hospital cardiac arrest: A feasibility study	6
Effects of arginase genetic polymorphisms on nitric oxide formation in healthy pregnancy and in preeclampsia	6
Challenging development of storable particles for oral delivery of a physiological nitric oxide donor	6
Alcohol hangover induces nitric oxide metabolism changes by impairing NMDA receptor-PSD95-nNOS pathway	6
Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism	6
Animal models of hypertension: The status of nitric oxide and oxidative stress and the role of the renal medulla	6
Nitric oxide displays a biphasic effect on calcium dynamics in microglia	6
Combined inorganic nitrate/nitrite supplementation blunts α-mediated vasoconstriction during exercise in patients with type 2 diabetes	5
Decreased expression of neuronal nitric oxide synthase contributes to the endothelial dysfunction associated with cigarette smoking in human	5
There is no direct competition between arginase and nitric oxide synthase for the common substrate l-arginine	5
Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury	5
Targeting hydrogen sulfide and nitric oxide to repair cardiovascular injury after trauma	5
H2S signaling and extracellular matrix remodeling in cardiovascular diseases: A tale of tense relationship	5
Marching to the Beet: The effect of dietary nitrate supplementation on high altitude exercise performance and adaptation during a military trekking expedition	5
Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase	5
Y12 nitration of human calcitonin (hCT): A promising strategy to produce non-aggregation bioactive hCT	5
Involvement of nitric oxide in the neurobiology of fear-like behavior	5
Protein nitration induced by Hemin/NO: A complementary mechanism through the catalytic functions of hemin and NO-scavenging	5
TRPC channel-derived calcium fluxes differentially regulate ATP and flow-induced activation of eNOS	5
Nitric oxide and hormesis	5
The effect of dietary nitrate on exercise capacity in chronic kidney disease: a randomized controlled pilot study	5
Effect of nitric oxide inhibition in Bacillus Calmette-Guerin bladder cancer treatment	5
The regulatory role of MiR-203 in oxidative stress induced cell injury through the CBS/H2S pathway	5
Procognitive activity of nitric oxide inhibitors and donors in animal models	5
Hypochlorous acid facilitates inducible nitric oxide synthase subunit dissociation: The link between heme destruction, disturbance of the zinc-tetrathiolate center, and the prevention by melatonin	5
Dietary nitrate biochemistry and physiology. An update on clinical benefits and mechanisms of action	5
Myoglobin promotes nitrite-dependent mitochondrial S-nitrosation to mediate cytoprotection after hypoxia/reoxygenation	5
Activation of transcription factor HIF inhibits IL-1β-induced NO production in primary cultured rat hepatocytes	5
Potential role for age as a modulator of oral nitrate reductase activity	5
Utility of NO and H2S donating platforms in managing COVID-19: Rationale and promise	4
Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice	4
The new organic nitrate 2-nitrate-1,3-diocthanoxypropan (NDOP) induces nitric oxide production and vasorelaxation via activation of inward-rectifier potassium channels (KIR)	4
Dual role of nitric oxide in Alzheimer's disease	4
Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system	4
Nitric oxide in the Marfan vasculature: Friend or foe?	4
ADMA and homoarginine independently predict mortality in critically ill patients	4
Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action	4
The synthetic peptide PnPP-19 potentiates erectile function via nNOS and iNOS	4
The activity of IKCa and BKCa channels contributes to insulin-mediated NO synthesis and vascular tone regulation in human umbilical vein	4
Exhaled and nasal NO measurement: NO in your breath doesn’t imply a negative attitude!	4
Ghrelin activates the mesolimbic dopamine system via nitric oxide associated mechanisms in the ventral tegmental area	4
Hydrogen sulfide potentiates the protective effects of nitrite against myocardial ischemia-reperfusion injury in type 2 diabetic rats	4
Analysis of glutathione mediated S-(de)nitrosylation in complex biological matrices by immuno-spin trapping and identification of two novel substrates	3
Nitric oxide inhibits alginate biosynthesis in Pseudomonas aeruginosa and increases its sensitivity to tobramycin by downregulating algU gene expression	3
Nitric oxide synthases from photosynthetic organisms improve growth and confer nitrosative stress tolerance in E. coli. Insights on the pterin cofactor	3
Hydrogen sulfide potently promotes neuronal differentiation of adipose tissue-derived stem cells involving nitric oxide-mediated signaling cascade with the aid of cAMP-elevating agents	3
An updated systematic review and meta-analysis of the effect of statins on asymmetric dimethylarginine	3
Short-term beetroot juice supplementation improves muscle speed and power but does not reduce blood pressure or oxidative stress in 65–79 y old men and women	3
Nitric oxide mediated hypoxia dynamics in COVID-19	3
Regulation of nitrite reductase and lipid binding properties of cytoglobin by surface and distal histidine mutations	3
Organic mercury solid phase chemoselective capture for proteomic identification of S-nitrosated proteins and peptides	3
Nitric oxide and long-term outcomes after kidney transplantation: Results of the TransplantLines cohort study	3
The importance of the endothelial nitric oxide synthase on the release of 6-nitrodopamine from mouse isolated atria and ventricles and their role on chronotropism	3
The role of adipose tissue-derived hydrogen sulfide in inhibiting atherosclerosis	3
Bradykinin promotes murine melanoma cell migration and invasion through endogenous production of superoxide and nitric oxide	3
Inhaled nitric oxide reduces the intrapulmonary shunt to ameliorate severe hypoxemia after acute type A aortic dissection surgery	3
Systemic NOS inhibition reduces contracting muscle oxygenation more in intact female than male rats	3
Endogenous hydrogen sulfide promotes human preimplantation embryonic development by regulating metabolism-related gene expression	3
The procoagulant effects of extracellular vesicles derived from hypoxic endothelial cells can be selectively inhibited by inorganic nitrite	3
Effects of low doses of different nitric oxide (NO) donors in rat models of obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD)	3
Nitric oxide synthase inhibition with N(G)-monomethyl-l-arginine: Determining the window of effect in the human vasculature	3

Essential role for neuronal nitric oxide synthase in acute ethanol-induced motor impairment	3
Platelet dysfunction in a large-animal model of endotoxic shock; effects of inhaled nitric oxide and low-dose steroid	3
Polysulfides derived from the hydrogen sulfide and persulfide donor P* inhibit IL-1β-mediated inducible nitric oxide synthase signaling in ATDC5 cells: are CCAAT/enhancer-binding proteins β and δ invo	3
Bystander effect in photosensitized prostate cancer cells with a different grade of malignancy: The role of nitric oxide	3
Multiple-day high-dose beetroot juice supplementation does not improve pulmonary or muscle deoxygenation kinetics of well-trained cyclists in normoxia and hypoxia	3