Nature Biotechnology

Papers
(The H4-Index of Nature Biotechnology is 108. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)
ArticleCitations
Forum: Alexandrov and Le1450
Federation Bio: from single strains to a purely synthetic microbiome1024
People959
Forum: Optogenetics roundtable with Deisseroth and Gradinaru800
Multiplexed mapping of chromatin features at single-cell resolution623
First Rounders: Jay Keasling558
Synthetic GPCRs for controlling cellular responses498
Base editors483
Forum: CRISPR screening roundtable with Stegmaier and Doench424
People419
Biotech news from around the world415
Bilateral China–Brazil ties over agbiotech406
Bluebird’s CALD gene therapy poised for approval404
Biotech news from around the world377
Bat biotech takes flight371
Biotech news from around the world346
Diffusion model expands RoseTTAFold’s power344
Fungal architecture is a thing, and it’s eye-catching336
Engineered Cas13 variants with minimal collateral RNA targeting326
People320
Linking genetic variants to cellular function and disease299
Ultra-precision medicine295
First Rounders: Lita Nelsen281
Photys Therapeutics: customizing phosphorylation via molecular matchmaking281
The champions of drug development275
Putting CRISPR into African hands to future-proof crops265
Women build strength in numbers261
Synthetic biologics provide a path to target bHLH transcription factors260
Unlocking drug modes of action with multi-dimensional high-throughput metabolic profiling257
A neural network for long-term super-resolution imaging of live cells with reliable confidence quantification256
Increase vigilance against cyberattacks254
Patents benefit patients and patent reform would spur diagnostic and therapeutic development253
Biotech news from around the world232
Vector BioPharma: resurrecting adenoviral gene delivery230
Fluorescence microscopy resolution increases to near-atomic level229
Multiplex-GAM detects complex chromatin interactions229
Eight diseases for gene therapy accelerator228
People225
Wearable devices224
Decoding the building blocks of cellular processes from single-cell transcriptomics data217
Editor’s pick: Tenpoint Therapeutics217
Spanish tortillas go vegan216
HIV drug 100% protective214
A base editor modifies bacterial genes in the guts of living mice214
Personalized medicine is having its day212
Biotech news from around the world211
Protein design: the experts speak207
Radical solutions205
Big pharma craves slice of AI-based RNA drug discovery201
Monitoring protein proximity with fluorogens196
Nanopore sequencing190
Base editing marches on the clinic189
Detecting somatic mutations in single-cell data sets177
Precise intraoperative brain tumor classification176
An improved organoid model of the human cerebellum170
Startups probe hidden viruses in the ‘dark genome’ to treat disease170
Merck enlists trispecific killers168
Cancer Moonshot aims at liquid biopsies167
Single-cell multi-omics allows functional characterization of structural variants164
AI’s plastic recycling162
FDA okays first cardiac myosin inhibitor158
Biotech news from around the world157
Citizen chickpeas154
Single-cell RNA-seq keeps cells alive152
Vision–language AI assistance in human pathology152
100,000 genomes — in Africa, for Africa152
Biotech news from around the world151
People149
Has the PTAB made a difference in drug settlements and generic entry?148
In vivo CRISPR agent cuts HAE attacks 95%147
Supercharging T cell therapy with cancer mutations145
Single-molecule peptide sequencing on semiconductor chips144
Exploring tRNAs and their modifications and crosstalk using Nano-tRNAseq142
Around the world in a month141
Lentiviral vector cleared of causing blood cancer137
Editor’s pick: Switch Therapeutics136
Five questions with Weixin Tang136
Cellular shuttles put mislocalized proteins in their right place135
T cells135
An antigen discovery pipeline integrates multi-omics data and informs immunotherapy133
TRGT-ing the dark genome to accurately characterize tandem repeats at scale133
Uncovering the global RNA virome131
Government targets, end-of-year patenting rush and innovative performance in China130
Industry moves on 3Rs129
People128
Organoids and organs on a chip127
Spatial characterization of single tumor cells by proteomics127
Machine learning in drug discovery127
Denmark invests in mucosal vaccines126
Toward a safer and more secure US bioeconomy125
Mining extinct proteomes for antimicrobial peptides125
Glia-enriched cortical organoids implanted in mice capture astrocyte diversity124
Making space for spatial biology in the clinic122
Video game unleashes millions of citizen scientists on microbiome research121
Capturing and modeling cellular niches from dissociated single-cell and spatial data121
Sound healing and beyond119
CRISPR-free, strand-selective mitochondrial DNA base editing using a nickase115
AI for drug discovery is booming, but who owns the patents?114
Wireless microelectronic fibers to discover gut and brain pathways113
Identification of antimicrobial peptides from the human gut microbiome using deep learning112
Chroma Medicine and Tune Therapeutics: Two companies take up epigenome editing112
Club-goers take first bites of lab-made chicken111
Startup tackles oncogene-rich ecDNA111
CRISPR therapies march into clinic, but genotoxicity concerns linger111
Inferring cell–cell communication at single-cell resolution110
RNA drugs lower lipoprotein(a) and genetically driven cholesterol110
The lysosomal degraders110
Genotoxic effects of base and prime editing in human hematopoietic stem cells108
A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH108
Unidirectional single-file transport of full-length proteins through a nanopore108
Real-time monitoring of tumor-homing bacteria and tumor cells in vivo using ultrasound108
Prime editing using CRISPR-Cas12a and circular RNAs in human cells108
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