Seminars in Cell & Developmental Biology

Article	Citations
TGF-β1 – A truly transforming growth factor in fibrosis and immunity	257
Interaction between bone and immune cells: Implications for postmenopausal osteoporosis	204
Spindle assembly checkpoint activation and silencing at kinetochores	121
The substrate repertoire of γ-secretase/presenilin	113
Non-canonical (non-SMAD2/3) TGF-β signaling in fibrosis: Mechanisms and targets	94
Hepatic lipid droplet homeostasis and fatty liver disease	87
Motile cilia and airway disease	85
Filopodia and their links with membrane traffic and cell adhesion	80
Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin	80
Iron in immune cell function and host defense	80
Direct trafficking pathways from the Golgi apparatus to the plasma membrane	78
Mammalian cell cycle cyclins	77
Origin and evolution of gibberellin signaling and metabolism in plants	76
GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer’s disease	75
Microglia and lipids: how metabolism controls brain innate immunity	74
Evolution and functional diversification of FLOWERING LOCUS T/TERMINAL FLOWER 1 family genes in plants	71
Magnesium and inflammation: Advances and perspectives	64
Mechanisms regulating myoblast fusion: A multilevel interplay	64
Senotherapeutics: Targeting senescence in idiopathic pulmonary fibrosis	62
Towards a structural understanding of the remodeling of the actin cytoskeleton	61
Lipid droplets in plants and algae: Distribution, formation, turnover and function	60
LC3-associated phagocytosis - The highway to hell for phagocytosed microbes	59
Developmental and regenerative paradigms of cilia regulated hedgehog signaling	58
Transcriptional regulation of multiciliated cell differentiation	57
Mitotic chromosomes	57

Human placental development and function	55
Primary cilia biogenesis and associated retinal ciliopathies	55
Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases	53
Tracing insights into de novo lipogenesis in liver and adipose tissues	53
Aluminium adjuvants in vaccines – A way to modulate the immune response	52
Convergent extension in mammalian morphogenesis	52
Autophagy in intracellular bacterial infection	50
On the biosynthesis and evolution of apocarotenoid plant growth regulators	50
Endothelium-mediated contributions to fibrosis	50
Macrophage-mediated inflammation in diabetic wound repair	49
Sertoli cells as key drivers of testis function	49
Synovial fibroblasts and articular tissue remodelling: Role and mechanisms	48
Metabolic regulation of calcium signaling in beta cells	48
Intraflagellar transport trains and motors: Insights from structure	47
Lipid droplet biogenesis: A mystery “unmixing”?	46
Visual adaptations of diurnal and nocturnal raptors	46
The molecular basis of mammary gland development and epithelial differentiation	46
Human and mouse skeletal muscle stem and progenitor cells in health and disease	45
Role of autophagy during plant-virus interactions	44
Manipulation of autophagy by (+) RNA viruses	44
Contribution of the Presenilins in the cell biology, structure and function of γ-secretase	44
RIPK protein kinase family: Atypical lives of typical kinases	42
Cellular and molecular mechanisms of liver regeneration: Proliferation, growth, death and protection of hepatocytes	42
Human centrosome organization and function in interphase and mitosis	42
Mechanisms of protein targeting to lipid droplets: A unified cell biological and biophysical perspective	42
A fork in the road: Where homologous recombination and stalled replication fork protection part ways	42
A centralized communication network: Recent insights into the role of the cancer associated fibroblast in the development of drug resistance in tumors	40
RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease	40
Pancreatic α-cells – The unsung heroes in islet function	40
Lung regeneration: a tale of mice and men	40
Lipid metabolism in astrocytic structure and function	39
Kinetochore assembly throughout the cell cycle	39
Cilia signaling and obesity	39
Fundamentals of bone vasculature: Specialization, interactions and functions	38
Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration	37
Right, left and cilia: How asymmetry is established	37
RAD51: Beyond the break	37
Lipids in regulating oligodendrocyte structure and function	37
Aging: All roads lead to mitochondria	37
The biology of lipid droplet-bound mitochondria	37
The exceptional diversity of visual adaptations in deep-sea teleost fishes	36
Crossroads in the evolution of plant specialized metabolism	36
Nucleolar stress: From development to cancer	36
Inflammation during post-injury skeletal muscle regeneration	35
Life-long oligodendrocyte development and plasticity	35
Macrophage regulation of angiogenesis in health and disease	35
Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding	35
Roles of CDK/Cyclin complexes in transcription and pre-mRNA splicing: Cyclins L and CDK11 at the cross-roads of cell cycle and regulation of gene expression	35
Lipid droplets, bioenergetic fluxes, and metabolic flexibility	35
Visual system diversity in coral reef fishes	34

Contributions of alternative splicing to muscle type development and function	34
Upstream regulation of the Hippo-Yap pathway in cardiomyocyte regeneration	34
Cilia and polycystic kidney disease	33
Mechanisms of neurodegeneration — Insights from familial Alzheimer’s disease	33
Aging biomarkers and the brain	33
Role of Notch signaling in neurovascular aging and Alzheimer’s disease	33
Noradrenaline in the aging brain: Promoting cognitive reserve or accelerating Alzheimer's disease?	32
Excitable networks controlling cell migration during development and disease	32
Unraveling the complexity of γ-secretase	31
Selenoproteins as regulators of T cell proliferation, differentiation, and metabolism	31
Perisynaptic schwann cells - The multitasking cells at the developing neuromuscular junctions	30
Control of the chromatin response to DNA damage: Histone proteins pull the strings	30
SUMO-SIM interactions: From structure to biological functions	30
Chromoanagenesis, the mechanisms of a genomic chaos	30
Multigenerational epigenetic inheritance: Transmitting information across generations	30
Cellular complexity in brain organoids: Current progress and unsolved issues	29
Cilia, neural development and disease	29
Coming of age in the frontal cortex: The role of puberty in cortical maturation	29
Successive cleavage of β-amyloid precursor protein by γ-secretase	29
Making choices: DNA replication fork recovery mechanisms	29
Osteoclast formation at the bone marrow/bone surface interface: Importance of structural elements, matrix, and intercellular communication	29
Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage	29
Nuclear actin dynamics in gene expression and genome organization	29
Comparative mammary gland postnatal development and tumourigenesis in the sheep, cow, cat and rabbit: Exploring the menagerie	28
The adverse impact of cadmium on immune function and lung host defense	28
There and back again: An evolutionary perspective on long-distance coordination of plant growth and development	28
DNA double-strand break repair: Putting zinc fingers on the sore spot	28
The retinal basis of vision in chicken	28
Regulation of actin isoforms in cellular and developmental processes	28
From model organism to application: Bacteria-induced growth and development of the green seaweed Ulva and the potential of microbe leveraging in algal aquaculture	28
Molecular mechanisms of heart regeneration	27
Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases	27
Prolactin: A hormone with diverse functions from mammary gland development to cancer metastasis	27
On being the right shape: Roles for motile cilia and cerebrospinal fluid flow in body and spine morphology	27
Ciliogenesis membrane dynamics and organization	27
Synapse pathology in Alzheimer’s disease	27
A direct look at the dysfunction and pathology of the β cells in human type 2 diabetes	27
The many implications of actin filament helicity	27
RIPK2 NODs to XIAP and IBD	27
Therapeutic strategies for miRNA delivery to reduce hepatocellular carcinoma	26
Embryonic mammary gland development	26
The diverse roles of RIP kinases in host-pathogen interactions	26
Intrinsic and extrinsic regulators of oligodendrocyte progenitor proliferation and differentiation	26
25 years of research put RIPK1 in the clinic	26
Novel insights into the coupling of osteoclasts and resorption to bone formation	26
Synaptic modifications in learning and memory – A dendritic spine story	26
Regulation of mammalian spermatogenesis by miRNAs	25
Human CtIP: A ‘double agent’ in DNA repair and tumorigenesis	25
Sleep timing and the circadian clock in mammals: Past, present and the road ahead	25
Functions of TopBP1 in preserving genome integrity during mitosis	25
Role of cilia in the pathogenesis of congenital heart disease	25
Germ cell migration—Evolutionary issues and current understanding	25
Modeling neurological disorders using brain organoids	24
Myogenesis control by SIX transcriptional complexes	24
Transgenerational programming of nephron deficits and hypertension	24
Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells	24
The evolution of cytokinin signaling and its role in development before Angiosperms	24
Substrate recognition by TRIM and TRIM-like proteins in innate immunity	24
Experiment, theory, and the keratocyte: An ode to a simple model for cell motility	24
Genome (in)stability at tandem repeats	23
Integrated stress response in hepatitis C promotes Nrf2-related chaperone-mediated autophagy: A novel mechanism for host-microbe survival and HCC development in liver cirrhosis	23
Dickkopf signaling, beyond Wnt-mediated biology	23
The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis	23
The why and how of sleep-dependent synaptic down-selection	23
Cellular and molecular basis of liver regeneration	23
Modelling neurodegenerative disease using brain organoids	23
The road best traveled: Neural crest migration upon the extracellular matrix	23
Heart organoids and tissue models for modeling development and disease	23
A frog’s eye view: Foundational revelations and future promises	22
Muscle development : a view from adult myogenesis in Drosophila	22
Cellular evasion strategies of Helicobacter pylori in regulating its intracellular fate	22
Microfluidic organoids-on-a-chip: The future of human models	22
Tissue cross talks governing limb muscle development and regeneration	22
Oligodendrogenesis and myelination regulate cortical development, plasticity and circuit function	22
Endoplasmic Reticulum Protein Quality Control in β Cells	22
Histone H2A variants: Diversifying chromatin to ensure genome integrity	21
Sex differences in daily timekeeping and circadian clock circuits	21
Multifarious roles of lipid droplets in autophagy – Target, product, and what else?	21
The roles of microRNAs in regulation of autophagy during bacterial infection	21
Hydrostatic pressure as a driver of cell and tissue morphogenesis	21

Principles and functions of pericentromeric satellite DNA clustering into chromocenters	21
Patterning and mechanics of somite boundaries in zebrafish embryos	21
Anti-fibrotic mechanisms of exogenously-expanded mesenchymal stromal cells for fibrotic diseases	21
Chromothripsis as a pathogenic driver of multiple myeloma	21
Bioengineering tissue morphogenesis and function in human neural organoids	20
Thyroid hormone, gene expression, and Central Nervous System: Where we are	20
Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo	20
Death versus dedifferentiation: The molecular bases of beta cell mass reduction in type 2 diabetes	20
Mechanical regulation of formin-dependent actin polymerization	20
Long non-coding RNAs in antiviral immunity	20
Axes of visual adaptation in the ecologically diverse family Cichlidae	20
Anaphase B: Long-standing models meet new concepts	20
Deconstructing and reconstructing the human brain with regionally specified brain organoids	20
Regulatory mechanisms of RIPK1 in cell death and inflammation	20
A classical revival: Human satellite DNAs enter the genomics era	20
Growth and mechanobiology of the tendon-bone enthesis	20
Stem Leydig cells: Current research and future prospects of regenerative medicine of male reproductive health	20
Viral non-coding RNAs: Stealth strategies in the tug-of-war between humans and herpesviruses	20
Manganese homeostasis at the host-pathogen interface and in the host immune system	19
Rationally-based therapeutic disease modification in systemic sclerosis: Novel strategies	19
γ-Secretase inhibitors and modulators: Mechanistic insights into the function and regulation of γ-Secretase	19
Tenascin-C in fibrosis in multiple organs: Translational implications	19
The metaphase spindle at steady state – Mechanism and functions of microtubule poleward flux	19
New friends for seipin — Implications of seipin partner proteins in the life cycle of lipid droplets	19
Developmental regulation of excitatory-inhibitory synaptic balance in the prefrontal cortex during adolescence	19
The dynamics of γ-secretase and its substrates	19
Biogenesis of circular RNAs and their role in cellular and molecular phenotypes of neurological disorders	19
Mammary gland development from a single cell ‘omics view	19
A focus on yeast mating: From pheromone signaling to cell-cell fusion	18
Vertebrate Wnt5a – At the crossroads of cellular signalling	18
Centrosome dysfunction in human diseases	18
The detyrosination/re-tyrosination cycle of tubulin and its role and dysfunction in neurons and cardiomyocytes	18
Control of cardiomyocyte differentiation timing by intercellular signaling pathways	18
Genome instability from nuclear catastrophe and DNA damage	18
Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis	18
Clustered cell migration: Modeling the model system of Drosophila border cells	18
The essence of the engram: Cellular or synaptic?	18
Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition	18
Insights regarding skin regeneration in non-amniote vertebrates: Skin regeneration without scar formation and potential step-up to a higher level of regeneration	18
Evolution of CLE peptide signalling	18
Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization	18
Establishing compartment boundaries in Drosophila wing imaginal discs: An interplay between selector genes, signaling pathways and cell mechanics	17
Pubertal mammary gland development is a key determinant of adult mammographic density	17
MicroRNA regulation of prefrontal cortex development and psychiatric risk in adolescence	17
MicroRNAs in shaping the resolution phase of inflammation	17
The multiple functions of hindbrain boundary cells: Tinkering boundaries?	17
Regulating metabolism to shape immune function: Lessons from Drosophila	17
Actin-based regulation of ciliogenesis – The long and the short of it	17
Brain organoids, consciousness, ethics and moral status	17
Cilia and centrosomes: Ultrastructural and mechanical perspectives	17
The homeostatic regulation of ribosome biogenesis	17
The De-, Re-, and trans-differentiation of β-cells: Regulation and function	16
MicroRNAs: Harbingers and shapers of periodontal inflammation	16
A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity	16
Less-well known functions of cyclin/CDK complexes	16
Roadblocks and fast tracks: How RNA binding proteins affect the viral RNA journey in the cell	16
Copper in infectious disease: Using both sides of the penny	16
Vision in sharks and rays: Opsin diversity and colour vision	16
Estrogens and the circadian system	16
Dissecting the neurobiology of linguistic disorganisation and impoverishment in schizophrenia	16
Brain-based mechanisms of late-life depression: Implications for novel interventions	16
The molecular clockwork of mammalian cells	16
Neuronal filopodia: From stochastic dynamics to robustness of brain morphogenesis	16
Function of peripheral nerves in the development and healing of tendon and bone	16
Spatial regulation of mTORC1 signalling: Beyond the Rag GTPases	16
The interplay of autophagy and enterovirus	15
Nuclear positioning during development: Pushing, pulling and flowing	15
The centriolar tubulin code	15
Mechanistic origins of diverse genome rearrangements in cancer	15
The impact of ageing and sex on sympathetic neurocirculatory regulation	15
Endothelial cell mechanics and blood flow forces in vascular morphogenesis	15
The lifecycle of the neuronal microtubule transport machinery	15
Tissue segregation in the early vertebrate embryo	15
Directing with restraint: Mechanisms of protrusion restriction in collective cell migrations	15
Neuronal ensembles in memory processes	15
Nuclear size and shape control	15
Centrosome structure and biogenesis: Variations on a theme?	15
RIPK1 ubiquitination: Evidence, correlations and the undefined	15
Effect of varicoceles on spermatogenesis	15
Role of cyclins and cyclin-dependent kinases in pluripotent stem cells and their potential as a therapeutic target	15
The m6A-epitranscriptome in brain plasticity, learning and memory	15
A unifying model for extrachromosomal circular DNA load in eukaryotic cells	15
The future of cerebral organoids in drug discovery	15
Impact of the actin cytoskeleton on cell development and function mediated via tropomyosin isoforms	15