Seminars in Cell & Developmental Biology

Article	Citations
Interaction between bone and immune cells: Implications for postmenopausal osteoporosis	319
Spindle assembly checkpoint activation and silencing at kinetochores	143
Hepatic lipid droplet homeostasis and fatty liver disease	118
Iron in immune cell function and host defense	110
Mammalian cell cycle cyclins	105
Motile cilia and airway disease	102
GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer’s disease	98
Evolution and functional diversification of FLOWERING LOCUS T/TERMINAL FLOWER 1 family genes in plants	96
Direct trafficking pathways from the Golgi apparatus to the plasma membrane	92
Magnesium and inflammation: Advances and perspectives	92
Dermal extracellular matrix molecules in skin development, homeostasis, wound regeneration and diseases	92
Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin	90
Origin and evolution of gibberellin signaling and metabolism in plants	86
Human placental development and function	85
Sertoli cells as key drivers of testis function	84
Microglia and lipids: how metabolism controls brain innate immunity	83
Macrophage-mediated inflammation in diabetic wound repair	80
Primary cilia biogenesis and associated retinal ciliopathies	71
Developmental and regenerative paradigms of cilia regulated hedgehog signaling	67
Aluminium adjuvants in vaccines – A way to modulate the immune response	67
Lipid droplets in plants and algae: Distribution, formation, turnover and function	67
Transcriptional regulation of multiciliated cell differentiation	65
Mitotic chromosomes	64
Synapse pathology in Alzheimer’s disease	64
Tracing insights into de novo lipogenesis in liver and adipose tissues	61

Crossroads in the evolution of plant specialized metabolism	58
Human centrosome organization and function in interphase and mitosis	57
Microfluidic organoids-on-a-chip: The future of human models	56
Macrophage regulation of angiogenesis in health and disease	55
On the biosynthesis and evolution of apocarotenoid plant growth regulators	55
The molecular basis of mammary gland development and epithelial differentiation	55
Intraflagellar transport trains and motors: Insights from structure	54
RIPK protein kinase family: Atypical lives of typical kinases	53
Mechanisms of protein targeting to lipid droplets: A unified cell biological and biophysical perspective	52
Lipid metabolism in astrocytic structure and function	52
Life-long oligodendrocyte development and plasticity	51
A fork in the road: Where homologous recombination and stalled replication fork protection part ways	50
Lipid droplet biogenesis: A mystery “unmixing”?	49
Right, left and cilia: How asymmetry is established	49
Nucleolar stress: From development to cancer	49
Aging: All roads lead to mitochondria	47
RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease	47
The biology of lipid droplet-bound mitochondria	46
Role of Notch signaling in neurovascular aging and Alzheimer’s disease	45
Lipids in regulating oligodendrocyte structure and function	43
RAD51: Beyond the break	43
Cilia signaling and obesity	42
Aging biomarkers and the brain	42
From model organism to application: Bacteria-induced growth and development of the green seaweed Ulva and the potential of microbe leveraging in algal aquaculture	41
Kinetochore assembly throughout the cell cycle	41
Fundamentals of bone vasculature: Specialization, interactions and functions	41
Lipid droplets, bioenergetic fluxes, and metabolic flexibility	41
Multigenerational epigenetic inheritance: Transmitting information across generations	39
Ciliogenesis membrane dynamics and organization	38
Inflammation during post-injury skeletal muscle regeneration	38
SUMO-SIM interactions: From structure to biological functions	38
Making choices: DNA replication fork recovery mechanisms	38
Cilia and polycystic kidney disease	37
Control of the chromatin response to DNA damage: Histone proteins pull the strings	37
Roles of CDK/Cyclin complexes in transcription and pre-mRNA splicing: Cyclins L and CDK11 at the cross-roads of cell cycle and regulation of gene expression	37
Noradrenaline in the aging brain: Promoting cognitive reserve or accelerating Alzheimer's disease?	37
Coming of age in the frontal cortex: The role of puberty in cortical maturation	37
Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage	37
Chromoanagenesis, the mechanisms of a genomic chaos	37
Selenoproteins as regulators of T cell proliferation, differentiation, and metabolism	36
Comparative mammary gland postnatal development and tumourigenesis in the sheep, cow, cat and rabbit: Exploring the menagerie	35
Cellular complexity in brain organoids: Current progress and unsolved issues	35
Crossing boundaries: Interplay between the immune system and oligodendrocyte lineage cells	35
Cilia, neural development and disease	35
The adverse impact of cadmium on immune function and lung host defense	35
DNA double-strand break repair: Putting zinc fingers on the sore spot	34
There and back again: An evolutionary perspective on long-distance coordination of plant growth and development	33
Regulation of mammalian spermatogenesis by miRNAs	33
Human CtIP: A ‘double agent’ in DNA repair and tumorigenesis	33
Modeling neurological disorders using brain organoids	32

RIPK2 NODs to XIAP and IBD	32
Genome (in)stability at tandem repeats	32
Prolactin: A hormone with diverse functions from mammary gland development to cancer metastasis	32
Hydrostatic pressure as a driver of cell and tissue morphogenesis	31
Therapeutic strategies for miRNA delivery to reduce hepatocellular carcinoma	31
Developmental regulation of excitatory-inhibitory synaptic balance in the prefrontal cortex during adolescence	31
The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis	31
Synaptic modifications in learning and memory – A dendritic spine story	31
Role of cilia in the pathogenesis of congenital heart disease	30
Dickkopf signaling, beyond Wnt-mediated biology	30
Substrate recognition by TRIM and TRIM-like proteins in innate immunity	30
Oligodendrogenesis and myelination regulate cortical development, plasticity and circuit function	30
Osteoclast formation at the bone marrow/bone surface interface: Importance of structural elements, matrix, and intercellular communication	30
The detyrosination/re-tyrosination cycle of tubulin and its role and dysfunction in neurons and cardiomyocytes	30
Sleep timing and the circadian clock in mammals: Past, present and the road ahead	29
25 years of research put RIPK1 in the clinic	29
Novel insights into the coupling of osteoclasts and resorption to bone formation	29
Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases	29
The diverse roles of RIP kinases in host-pathogen interactions	29
The essence of the engram: Cellular or synaptic?	29
Embryonic mammary gland development	29
Functions of TopBP1 in preserving genome integrity during mitosis	28
The why and how of sleep-dependent synaptic down-selection	28
The homeostatic regulation of ribosome biogenesis	28
On being the right shape: Roles for motile cilia and cerebrospinal fluid flow in body and spine morphology	28
Sex differences in daily timekeeping and circadian clock circuits	28
Intrinsic and extrinsic regulators of oligodendrocyte progenitor proliferation and differentiation	28
A classical revival: Human satellite DNAs enter the genomics era	28
Olfactory modulation of the medial prefrontal cortex circuitry: Implications for social cognition	28
Ubiquitin-mediated mechanisms of translational control	27
Growth and mechanobiology of the tendon-bone enthesis	27
Manganese homeostasis at the host-pathogen interface and in the host immune system	27
A focus on yeast mating: From pheromone signaling to cell-cell fusion	26
Principles and functions of pericentromeric satellite DNA clustering into chromocenters	26
Modelling neurodegenerative disease using brain organoids	26
Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo	26
Histone H2A variants: Diversifying chromatin to ensure genome integrity	26
Heart organoids and tissue models for modeling development and disease	26
Reframing research on evolutionary novelty and co-option: Character identity mechanisms versus deep homology	25
The evolution of cytokinin signaling and its role in development before Angiosperms	25
Brain organoids, consciousness, ethics and moral status	25
RNA Polymerases I and III in development and disease	25
Patterning and mechanics of somite boundaries in zebrafish embryos	25
Tenascin-C in fibrosis in multiple organs: Translational implications	25
Anaphase B: Long-standing models meet new concepts	24
Evolution of holocentric chromosomes: Drivers, diversity, and deterrents	24
Long non-coding RNAs in antiviral immunity	24
Estrogens and the circadian system	24
Bioengineering tissue morphogenesis and function in human neural organoids	24
Stem Leydig cells: Current research and future prospects of regenerative medicine of male reproductive health	24
Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis	23
Ubiquitin and Legionella: From bench to bedside	23
The role of genetic risk factors of Alzheimer's disease in synaptic dysfunction	23
Effect of varicoceles on spermatogenesis	23
Imaging fetal anatomy	23
Regulatory mechanisms of RIPK1 in cell death and inflammation	23
The metaphase spindle at steady state – Mechanism and functions of microtubule poleward flux	23
Mammary gland development from a single cell ‘omics view	22
Evolution of CLE peptide signalling	22
Viral non-coding RNAs: Stealth strategies in the tug-of-war between humans and herpesviruses	22
Impairments of glutamatergic synaptic transmission in Alzheimer’s disease	22
Tubulin mutations in human neurodevelopmental disorders	22
Deconstructing and reconstructing the human brain with regionally specified brain organoids	22
Regulating metabolism to shape immune function: Lessons from Drosophila	22
The centriolar tubulin code	22
Lipid profiling of brain tissue and blood after traumatic brain injury	22
Neuronal filopodia: From stochastic dynamics to robustness of brain morphogenesis	22
Copper in infectious disease: Using both sides of the penny	21
MicroRNA regulation of prefrontal cortex development and psychiatric risk in adolescence	21
Multifarious roles of lipid droplets in autophagy – Target, product, and what else?	21
Thyroid hormone, gene expression, and Central Nervous System: Where we are	21
Chromothripsis as a pathogenic driver of multiple myeloma	21
New friends for seipin — Implications of seipin partner proteins in the life cycle of lipid droplets	21
Function of peripheral nerves in the development and healing of tendon and bone	21
Nuclear positioning during development: Pushing, pulling and flowing	21
MicroRNAs in shaping the resolution phase of inflammation	20
Genome instability from nuclear catastrophe and DNA damage	20
Pubertal mammary gland development is a key determinant of adult mammographic density	20
Hypertension-related risk for dementia: A summary review with future directions	20
Brain-based mechanisms of late-life depression: Implications for novel interventions	20

A unifying model for extrachromosomal circular DNA load in eukaryotic cells	20
Neural crest cells as a source of microevolutionary variation	20
Revealing cell vulnerability in Alzheimer’s disease by single-cell transcriptomics	20
Roadblocks and fast tracks: How RNA binding proteins affect the viral RNA journey in the cell	20
Control of cardiomyocyte differentiation timing by intercellular signaling pathways	20
The impact of ageing and sex on sympathetic neurocirculatory regulation	20
Vertebrate Wnt5a – At the crossroads of cellular signalling	20
Mechanics of epidermal morphogenesis in the Drosophila pupa	20
Viral miRNA regulation of host gene expression	19
The future of cerebral organoids in drug discovery	19
A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity	19
Dissecting the neurobiology of linguistic disorganisation and impoverishment in schizophrenia	19
Biogenesis of circular RNAs and their role in cellular and molecular phenotypes of neurological disorders	19
Endothelial cell mechanics and blood flow forces in vascular morphogenesis	19
Circadian clock synchrony and chronotherapy opportunities in cancer treatment	19
Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly	19
Implications of mRNA translation dysregulation for neurological disorders	19
Centrosome dysfunction in human diseases	19
Mechanics and self-organization in tissue development	19
Spatial regulation of mTORC1 signalling: Beyond the Rag GTPases	19
MicroRNAs: Harbingers and shapers of periodontal inflammation	18
The molecular clockwork of mammalian cells	18
Epigenetic regulation of immunosuppressive tumor-associated macrophages through dysregulated microRNAs	18
Establishing compartment boundaries in Drosophila wing imaginal discs: An interplay between selector genes, signaling pathways and cell mechanics	18
Composition and function of stress granules and P-bodies in plants	18
Cilia and centrosomes: Ultrastructural and mechanical perspectives	18
Persistent behavioral and neurobiological consequences of social isolation during adolescence	18
Role of cyclins and cyclin-dependent kinases in pluripotent stem cells and their potential as a therapeutic target	18
Maturing heart muscle cells: Mechanisms and transcriptomic insights	18
Skeletal muscle fibers count on nuclear numbers for growth	18
Single cell RNA sequencing approaches to cardiac development and congenital heart disease	17
Mechanistic origins of diverse genome rearrangements in cancer	17
The multiple functions of hindbrain boundary cells: Tinkering boundaries?	17
Emerging functions of thrombospondin-1 in immunity	17
Less-well known functions of cyclin/CDK complexes	17
Keratin 17 in psoriasis: Current understanding and future perspectives	17
An ‘Arms Race’ between the Nonsense-mediated mRNA Decay Pathway and Viral Infections	17
Membrane-actin interactions in morphogenesis: Lessons learned from Drosophila cellularization	17
Wiring of higher-order cortical areas: Spatiotemporal development of cortical hierarchy	17
The lifecycle of the neuronal microtubule transport machinery	17
Alliances of the gut and bone axis	17
Direct reprogramming as a route to cardiac repair	17
Morphogenesis of the human preimplantation embryo: bringing mechanics to the clinics	17
eIF2-dependent translation initiation: Memory consolidation and disruption in Alzheimer’s disease	17
An organismal understanding of C. elegans innate immune responses, from pathogen recognition to multigenerational resistance	17
Cell sorting and morphogenesis in early Drosophila embryos	17
Mechanisms of epigenetic regulation by C. elegans nuclear RNA interference pathways	17
The m6A-epitranscriptome in brain plasticity, learning and memory	16
Genome diversity and instability in human germ cells and preimplantation embryos	16
Nuclear size and shape control	16
RIPK1 ubiquitination: Evidence, correlations and the undefined	16
Extremophilic red algae as models for understanding adaptation to hostile environments and the evolution of eukaryotic life on the early earth	16
Ciliary signaling in stem cells in health and disease: Hedgehog pathway and beyond	16
The gut-brain axis and cognitive control: A role for the vagus nerve	16
Neuronal ensembles in memory processes	16
Exercise to Mend Aged-tissue Crosstalk in Bone Targeting Osteoporosis & Osteoarthritis	16
Chatterboxes: the structural and functional diversity of cyclins	16
Overview of the regulation of the class IA PI3K/AKT pathway by SUMO	16
Planar cell polarity (PCP) proteins support spermatogenesis through cytoskeletal organization in the testis	16
Multiple myeloma—A painful disease of the bone marrow	16
Non-coding RNAs in cardiac regeneration: Mechanism of action and therapeutic potential	16
Centrosome structure and biogenesis: Variations on a theme?	16
The developmental and evolutionary origins of cellular pluripotency in the vertebrate neural crest	16
Mechanical control of tissue shape: Cell-extrinsic and -intrinsic mechanisms join forces to regulate morphogenesis	16
The importance of virion-incorporated cellular RNA-Binding Proteins in viral particle assembly and infectivity	16
The evolution, formation and connectivity of the anterior commissure	16
Histone renegades: Unusual H2A histone variants in plants and animals	15
The ‘a, b, c’s of pretangle tau and their relation to aging and the risk of Alzheimer’s Disease	15
Implications of mitochondrial fusion and fission in skeletal muscle mass and health	15
Back to the new beginning: Mitotic exit in space and time	15
Taming human brain organoids one cell at a time	15
Temporal regulation of neural diversity in Drosophila and vertebrates	15
Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic	15
Feeling the force: Multiscale force sensing and transduction at the cell-cell interface	15
Tissue segregation in the early vertebrate embryo	15
Directing with restraint: Mechanisms of protrusion restriction in collective cell migrations	15
Transcription blockage by DNA damage in nucleotide excision repair-related neurological dysfunctions	15
Dynamic regulation of ribosome levels and translation during development	15
Epithelial to mesenchymal transition during mammalian neural crest cell delamination	15
Carnegie in 4D? Stem-cell-based models of human embryo development	15
Assigning function to SNPs: Considerations when interpreting genetic variation	15
Fibroblasts: The grey eminence of mammary gland development	15
Muscle-derived factors influencing bone metabolism	15
Regulatory roles of MicroRNA in shaping T cell function, differentiation and polarization	15
Temporal transitions in the postembryonic nervous system of the nematode Caenorhabditis elegans: Recent insights and open questions	15
Actions and interactions of IGF-I and MMPs during muscle regeneration	14
Histone variants in archaea – An undiscovered country	14
RINGO/Speedy proteins, a family of non-canonical activators of CDK1 and CDK2	14
Human epiblast lumenogenesis: From a cell aggregate to a lumenal cyst	14
Oligodendrocyte progenitors as environmental biosensors	14
Targeted protein degradation using intracellular antibodies and its application to neurodegenerative disease	14
Mechanical regulation of synapse formation and plasticity	14
Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems	14
The emerging role of miRNA in the perturbation of tumor immune microenvironment in chemoresistance: Therapeutic implications	14
The evolving role of abscisic acid in cell function and plant development over geological time	14