OOIR: Observatory of International Research

Papers

(The TQCC of Pharmaceutical Development and Technology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Solid lipid nanoparticles and nanostructured lipid carriers: a review of the methods of manufacture and routes of administration	57
Nanotechnologies for intranasal drug delivery: an update of literature	42
Sustained latanoprost release from PEGylated solid lipid nanoparticle-laden soft contact lens to treat glaucoma	34
Mucoadhesive chitosan and thiolated chitosan nanoparticles containing alpha mangostin for possible Colon-targeted delivery	31
Mucoadhesive polymeric films comprising polyvinyl alcohol, polyvinylpyrrolidone, and poloxamer 407 for pharmaceutical applications	26
Application of plant-derived exosome-like nanoparticles in drug delivery	22
An overview of PLGA in-situ forming implants based on solvent exchange technique: effect of formulation components and characterization	22
Gelatin-methacryloyl hydrogel based in vitro blood–brain barrier model for studying breast cancer-associated brain metastasis	21
The use of electronic tongue and sensory panel on taste evaluation of pediatric medicines: a systematic review	20
pH-sensitive chitosan-deoxycholic acid/alginate nanoparticles for oral insulin delivery	20
Pulmonary drug delivery with aerogels: engineering of alginate and alginate–hyaluronic acid microspheres	20
Recent advances in targeting malaria with nanotechnology-based drug carriers	19
Chitosan caged liposomes for improving oral bioavailability of rivaroxaban: in vitro and in vivo evaluation	19
Silver nanoparticles obtained from Brazilian pepper extracts with synergistic anti-microbial effect: production, characterization, hydrogel formulation, cell viability, and in vitro efficacy	19
An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M^® membrane and excised human skin	18
Dry powder inhalation formulation of chitosan nanoparticles for co-administration of isoniazid and pyrazinamide	17
Acriflavine-loaded solid lipid nanoparticles: preparation, physicochemical characterization, and anti-proliferative properties	16
Anti-ageing peptides and proteins for topical applications: a review	15
Simvastatin nanosuspensions prepared using a combination of pH-sensitive and timed-release approaches for potential treatment of colorectal cancer	15
Tabletability and compactibility of α-lactose monohydrate powders of different particle size. I. Experimental comparison	15
Preparation and functional evaluation of electrospun polymeric nanofibers as a new system for sustained topical ocular delivery of itraconazole	15
Electrospun orally disintegrating film formulation of telmisartan	14
In vitro and in vivo evaluation of an ionic sensitive in situ gel containing nanotransfersomes for aripiprazole nasal delivery	14
Boron phenyl alanine targeted ionic liquid decorated chitosan nanoparticles for mitoxantrone delivery to glioma cell line	14
Folic acid-hydrophilic polymer coated mesoporous silica nanoparticles target doxorubicin delivery	14

Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: formulation, characterization, in vitro-ex vivo evaluation	13
Cilnidipine loaded poly (ε-caprolactone) nanoparticles for enhanced oral delivery: optimization using DoE, physical characterization, pharmacokinetic, and pharmacodynamic evaluation	13
A promising dual-drug targeted delivery system in cancer therapy: nanocomplexes of folate–apoferritin-conjugated cationic solid lipid nanoparticles	13
Formulation optimization of solid self-microemulsifying pellets for enhanced oral bioavailability of curcumin	13
Preparation and optimization of silibinin-loaded chitosan–fucoidan hydrogel: an in vivo evaluation of skin protection against UVB	13
Microemulsion-thermosensitive gel composites as in situ-forming drug reservoir for periodontitis tissue repair through alveolar bone and collagen regeneration strategy	12
Targeted drug delivery via folate decorated nanocarriers based on linear polymer for treatment of breast cancer	11
Co-delivery of curcumin and Bcl-2 siRNA to enhance therapeutic effect against breast cancer cells using PEI-functionalized PLGA nanoparticles	11
Ocular microemulsion of brinzolamide: Formulation, physicochemical characterization, and in vitro irritation studies based on EpiOcular™ eye irritation assay	11
Pharmaceutical, biomedical and ophthalmic applications of biodegradable polymers (BDPs): literature and patent review	11
Glutamate-urea-based PSMA-targeted PLGA nanoparticles for prostate cancer delivery of docetaxel	11
Feasibility of developing hospital preparation by semisolid extrusion 3D printing: personalized amlodipine besylate chewable tablets	11
PLA-coated Imwitor^® 900 K-based herbal colloidal carriers as novel candidates for the intra-articular treatment of arthritis	10
Galactosylated iron oxide nanoparticles for enhancing oral bioavailability of ceftriaxone	10
Chitosan-bovine serum albumin-Carbopol 940 nanogels for mupirocin dermal delivery: ex-vivo permeation and evaluation of cellular binding capacity via radiolabeling	10
Investigations into the use of machine learning to predict drug dosage form design to obtain desired release profiles for 3D printed oral medicines	10
Emulsions with alkyl polyglucosides as carriers for off-label topical spironolactone – safety and stability evaluation	10
Development of a microencapsulated probiotic delivery system for New Zealand black-footed abalone (Haliotis iris)	10
Loading Pistacia atlantica essential oil in solid lipid nanoparticles and its effect on apoptosis of breast cancer cell line MDA-MB-231	10
In vitro and in vivo evaluations on nanoparticle and phospholipid hybrid nanoparticles with absorption enhancers for oral insulin delivery	10
Influence of process temperature and residence time on the manufacturing of amorphous solid dispersions in hot melt extrusion	9
Spray freeze-drying for inhalation application: process and formulation variables	9
Co-delivery of CPP decorated doxorubicin and CPP decorated siRNA by NGR-modified nanobubbles for improving anticancer therapy	9
An overview on the advantages and limitations of 3D printing of microneedles	9
Brain targeting of agomelatine egg lecithin based chitosan coated nanoemulsion	9
Calcitonin-loaded octamaleimic acid–silsesquioxane nanoparticles in hydrogel scaffold support osteoinductivity in bone regeneration	9
Rivaroxaban-loaded SLNs with treatment potential of deep vein thrombosis: in-vitro, in-vivo, and toxicity evaluation	9
Formulation of solid dispersion to improve dissolution and oral bioavailability of poorly soluble dexibuprofen	9
pH/enzyme dual sensitive and nucleus-targeting dendrimer nanoparticles to enhance the antitumour activity of doxorubicin	8
3D printing and enteric coating of a hollow capsular device with controlled drug release characteristics prepared using extruded Eudragit® filaments	8
Fast dissolving microneedle patch for pronounced systemic delivery of an antihyperlipidemic drug	8
Medicinal cannabis pharmacokinetics and potential methods of delivery	8
Alternatives to titanium dioxide in tablet coating	8
Insightful exploring of advanced nanocarriers for the topical/transdermal treatment of skin diseases	8
In vitro galactose-targeted study of RSPP050-loaded micelles against liver hepatocellular carcinoma	8
Chitosan-biotin topical film: preparation and evaluation of burn wound healing activity	8
Combating hematopoietic and hepatocellular abnormalities resulting from administration of cisplatin: role of liver targeted glycyrrhetinic acid nanoliposomes loaded with amino acids	8
Cholecalciferol complexation with hydroxypropyl-β-cyclodextrin (HPBCD) and its molecular dynamics simulation	8
Oridonin-loaded lipid-coated calcium phosphate nanoparticles: preparation, characterization, and application in A549 lung cancer	7
Bile acids as novel enhancers of CNS targeting antitumor drugs: a comprehensive review	7
Development and characterization of lyophilized cefpodoxime proxetil-Pluronic^® F127/polyvinylpyrrolidone K30 solid dispersions with improved dissolution and enhanced antibacterial activity	7
Different applications of temperature responsive nanogels as a new drug delivery system mini review	7
Preparation and characterization of dexamethasone lipid nanoparticles by membrane emulsification technique, use of self-emulsifying lipids as a carrier and stabilizer	7
Preparation and characterization of dicarboxylic acids salt of aripiprazole with enhanced physicochemical properties	7
A multivariate data analysis approach to tablet sticking on an industrial scale: a qualitative case study of an ibuprofen-based formulation	7
Development of ACE2 loaded decoy liposomes and their effect on SARS-CoV-2 for Covid-19 treatment	7
Enhanced dissolution and bioavailability of revaprazan using self-nanoemulsifying drug delivery system	7
Investigation of propellant-free aqueous foams as pharmaceutical carrier systems	7
Chitosan functionalized PCL nanoparticles bearing tyrosine kinase inhibitor osimertinib mesylate for effective lung cancer therapy	7
Dual-modified PCL-PEG nanoparticles for improved targeting and therapeutic efficacy of docetaxel against colorectal cancer	7

Microfluidics in drug delivery: review of methods and applications	7
Promising nanogels loaded with usnic acid for oral ulcer treatment: development, characterization, and in vivo evaluation in rabbits	7
An overview of polyallylamine applications in gene delivery	7
Drug delivery to the intestinal lymph by oral formulations	6
Exploiting synergistic effects of brittle and plastic excipients in directly compressible formulations of sitagliptin phosphate and sitagliptin hydrochloride	6
Surface modifications of gold nanoparticles: stabilization and recent applications in cancer therapy	6
Impact of highly phospholipid-containing lipid nanocarriers on oral bioavailability and pharmacodynamics performance of genistein	6
The effect of some acrylic polymers on dissolution of celecoxib solid dispersion formulations	6
Self-assembled micelles enhance the oral delivery of curcumin for the management of alcohol-induced tissue injury	6
Development of rebamipide-loaded spray-dried microsphere using distilled water and meglumine: physicochemical characterization and pharmacokinetics in rats	6
Evaluation of antitumor efficacy of folate-poly(2-ethyl-2-oxazoline)-distearoyl phosphatidyl ethanolamine based liposome	6
Chitosan as a potential biomaterial for the management of oral mucositis, a common complication of cancer treatment	6
Covalently coupling doxorubicin to polymeric nanoparticles as potential inhaler therapy:in vitrostudies	6
Development and characterization of an amorphous curcumin-Eudragit^®E100 solid dispersions with improved solubility, stability, and pharmacokinetic properties	6
Hyperoside-loaded TPGs/mPEG-PDLLA self-assembled polymeric micelles: preparation, characterization and in vitro/in vivo evaluation	6
In-vitro evaluation of dendrimeric formulation of oxaliplatin	6
Preparation, characterization, and anti-colon cancer activity of oridonin-loaded long-circulating liposomes	6
Exploring the use of niosomes in cosmetics for efficient dermal drug delivery	6
Ethanol-assisted kneading of apigenin with arginine for enhanced dissolution rate of apigenin: development of rapidly disintegrating tablets	6