Pharmaceutical Development and Technology

Papers
(The median citation count of Pharmaceutical Development and Technology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Formulation and optimization of a single-layer coat for targeting budesonide pellets to the descending Colon81
Development of PLGA-SPC3 functionalized gefitinib mesoporous silica nano-scaffolds for breast cancer targeting: biodistribution and cytotoxicity analysis51
Insights into tablet sticking: a quantitative case study with an ibuprofen and methocarbamol-based formulation42
Glycyrrhizic acid assists anti-psoriatic efficacy of a self-deformable curcumin loaded transdermal gel34
Influence of punch coating surface properties on sticking during the tableting process30
Facile fabrication of degradable, serrated polyethylene diacrylate microneedles using stereolithography27
Boron phenyl alanine targeted ionic liquid decorated chitosan nanoparticles for mitoxantrone delivery to glioma cell line22
Cationic Okra gum coated nanoliposomes as a pH-sensitive carrier for co-delivery of hesperetin and oxaliplatin in colorectal cancers21
Emulgels: a promising topical drug delivery system for arthritis management and care20
Preparation, characterization, and antibacterial activity of tigecycline-loaded, ultrasound-activated microbubbles20
Comparison study of physicochemical and biopharmaceutics properties of hydrophobic drugs ground by two dry milling processes19
Preparation and functional evaluation of electrospun polymeric nanofibers as a new system for sustained topical ocular delivery of itraconazole18
Formulation development, characterization, and evaluation of bedaquiline fumarate – Soluplus ® – solid dispersion17
Scale-up in twin-screw wet granulation: impact of formulation properties16
Sustained release of curcumin self-emulsifying drug delivery system (SEDDS) from solvent-cast Soluplus® films16
An innovative carrier for the formulation of amorphous solid dispersion by hot-melt extrusion with no further downstream processes: a case study with indomethacin.16
Sustained linagliptin administration: superior glycemic control and less pancreatic injury in diabetic rats15
Preformulation evaluation of selumetinib for topical application: skin distribution and photodegradation analysis using MALDI imaging and LC-MS/MS15
Permeability of olmesartan medoxomil from lipid based and suspension formulations using an optimized HDM-PAMPA model14
Development of an enhanced formulation to minimize pharmacokinetic variabilities of a weakly basic drug compound14
Newly developed nano-biocomposite embedded hydrogel to enhance drug loading and modulated release of anti-inflammatory drug14
Development of rebamipide-loaded spray-dried microsphere using distilled water and meglumine: physicochemical characterization and pharmacokinetics in rats14
Tabletability and compactibility of α-lactose monohydrate powders of different particle size. I. Experimental comparison14
Evaluating the color stability of titanium dioxide-free film coats under environmental and light stress14
Enhanced dissolution and bioavailability of revaprazan using self-nanoemulsifying drug delivery system13
Enhancement of the dissolution and in-vitro activity of a new antineoplastic agent13
Drug-silica-cellulose ternary matrix for the oral delivery of Cyclosporine A: in vitro and in vivo evaluation13
Solid self-microemulsifying drug delivery system (S-SMEDDS) prepared by spray drying to improve the oral bioavailability of cinnamaldehyde (CA)13
Preparation and anti-tumor activity of paclitaxel silk protein nanoparticles encapsulated by biofilm12
Preparation of a novel tacrolimus ion sensitive ocular in situ gel and in vivo evaluation of curative effect of immune conjunctivitis12
Preparation, in vitro anti-tumour activity and in vivo pharmacokinetics of RGD-decorated liposomes loaded with shikonin12
Intranasal delivery of sulpiride nanostructured lipid carrier to central nervous system; in vitro characterization and in vivo study12
Formation and stabilization mechanism of Ginsenoside Rg3 inclusion complexes based on molecular simulation11
Formulation of smokeless tobacco products with a wide range of pH to study nicotine pharmacokinetics and pharmacodynamics11
mRNA-based vaccines – global approach, challenges, and could be a promising wayout for future pandemics11
Correction11
Buccal lidocaine mucoadhesive patches for pediatrics’ teething pain: overcoming possible hazards of oral gels11
Targeted delivery strategy of indocyanine green-mitoxantrone loaded liposomes co-modified with BTP-7 and BR2 for the treatment of glioma11
Design and evaluation of erucic acid-phytosphingosine structured cationic nanoemulsions as a plasmid DNA delivery system against breast cancer cells11
Microfluidics in drug delivery: review of methods and applications10
Metoclopramide loaded buccal films for potential treatment of migraine symptoms: in vitro and in vivo study10
pH/enzyme dual sensitive and nucleus-targeting dendrimer nanoparticles to enhance the antitumour activity of doxorubicin10
Enhanced bioavailability and pharmacokinetics parameters of Enalapril solid self nanoemulsifying oral dispersible tablet: formulation, in vitro and in vivo evaluation10
Formulation design, optimization and in vivo evaluation of oral co-encapsulated resveratrol-humic acid colloidal polymeric nanocarriers10
Impact of grinding balls on the size reduction of Aprepitant in wet ball milling procedure10
Acriflavine-loaded solid lipid nanoparticles: preparation, physicochemical characterization, and anti-proliferative properties10
Modern trends in the formulation of microparticles for lung delivery using porogens: methods, principles and examples10
Development and characterization of an amorphous curcumin-Eudragit®E100 solid dispersions with improved solubility, stability, and pharmacokinetic properties9
Preparation and cytotoxicity evaluation of folic acid-modified YF8-OA self-assembled lipid prodrug nanoparticles9
Ethanol-assisted kneading of apigenin with arginine for enhanced dissolution rate of apigenin: development of rapidly disintegrating tablets9
Thermosensitive gel based on cellulose derivative for topical delivery of propolis in acne treatment9
Dual-modified PCL-PEG nanoparticles for improved targeting and therapeutic efficacy of docetaxel against colorectal cancer9
Extracellular vesicle-based formulation of doxorubicin: drug loading optimization, characterization, and cytotoxicity evaluation in tumor spheroids8
Sustained latanoprost release from PEGylated solid lipid nanoparticle-laden soft contact lens to treat glaucoma8
Lipid-Gelucire based rectal delivery of ramipril prodrug exhibits significant lowering of intra-ocular pressure in normotensive rabbit: sustained structural relaxation release kinetics and IVIVC8
Effect of different molecular weight and terminal group PLGA on docetaxel nanoparticles: characterization and cytotoxic activity of castration-resistant prostate cancer cells8
Improved transdermal permeability of tanshinone IIA from cataplasms by loading onto nanocrystals and porous silica7
Improvement of liraglutide release from PLGA microspheres by a porous microsphere-gel composite system7
Co-delivery of curcumin and Bcl-2 siRNA to enhance therapeutic effect against breast cancer cells using PEI-functionalized PLGA nanoparticles7
Ivermectin: recent approaches in the design of novel veterinary and human medicines7
An overview of PLGA in-situ forming implants based on solvent exchange technique: effect of formulation components and characterization7
Itraconazole-loaded microemulsions: formulation, characterization, and dermal delivery using shed snakeskin as the model membrane7
Chitosan-biotin topical film: preparation and evaluation of burn wound healing activity7
Manufacturing classification system (MCS): enabling better understanding of oral solid dosage formulation design7
The quest for down scale representativeness: how to exploit CFD to design a shear study for vaccines7
Dissolving microneedles loaded with nimodipine for prevention of sleep disorders at a high altitude6
Two-dimensional printing of nanoparticles as a promising therapeutic method for personalized drug administration6
Application of plant-derived exosome-like nanoparticles in drug delivery6
Controlled release of bioactive IL-2 from visible light photocured biodegradable elastomers for cancer immunotherapy applications6
Formulation and statistical optimization of letrozole loaded nanotransferosomal gel for tumor targeting6
The therapeutic efficacy and safety improvements of crizotinib prodrug micelles on breast cancer treatment6
An overview of polyallylamine applications in gene delivery6
Challenges and recent advances in erythropoietin stability6
Nanocarriers with long-term retention in the respiratory system for prolonged drug exposure6
Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes6
Preparation and evaluation of vancomycin spray-dried powders for pulmonary delivery6
Pharmaceutical applications and requirements of resins for printing by digital light processing (DLP)6
Cubosome-based thermosensitive in situ gelling system for intranasal administration of lamotrigine with enhanced antiepileptic efficacy6
Intranasal delivery of doxepin: enhancing brain targeting efficiency utilizing nanostructured lipid carriers for a biopharmaceutics drug disposition classification system class-I drug6
Stability of trastuzumab during nanomedicine formulation using SEC-HPLC coupled with polyacrylamide gel electrophoresis6
In vitro galactose-targeted study of RSPP050-loaded micelles against liver hepatocellular carcinoma6
Mannosylation of pH-sensitive liposomes promoted cytoplasmic delivery of protein to macrophages: green fluorescent protein (GFP) performed as an endosomal escape tracer6
NGR-poly(2-ethyl-2-oxazoline)-cholesteryl methyl carbonate enhances the antitumor effect of quercetin liposomes in triple-negative breast cancer6
Black seed oil boosts antidiabetic activity of glibenclamide: development of solidified self nanoemulsifying drug delivery system and evaluation in Streptozotocin-Induced diabetic rat model6
Porous microneedle arrays as promising tools for the quantification of drugs in the skin: a proof of concept study5
In-vitro evaluation of dendrimeric formulation of oxaliplatin5
Correction5
Exploring the use of niosomes in cosmetics for efficient dermal drug delivery5
The pioneering impact of artificial intelligence (AI) on pharmaceutical research and drug development (invited editorial)5
Enhanced skin penetration and clinical antifungal activity of eugenol encapsulated in aspasomes5
Nanosized ethosomal dispersions for enhanced transdermal delivery of nebivolol using intradermal/transfollicular sustained reservoir: in vitro evaluation, confocal laser5
Ionic liquids and their potential use in development and improvement of drug delivery systems: evidence of their tendency to promote drug accumulation in the brain5
The effect of some acrylic polymers on dissolution of celecoxib solid dispersion formulations5
The influence of input material properties on hot melt granules prepared using a counter-rotating batch mixer5
Formulation and performance evaluation of emulgel platform for combined skin delivery of curcumin and propolis5
Pharmaceutical excipients in pediatric and geriatric drug formulations: safety, efficacy, and regulatory perspectives5
Nanoparticle-based chewable gels of praziquantel5
Development of stabilized fuzapladib solution for injection: forced degradation study and pharmacokinetic evaluation5
Nanocoating and biological evaluation of clindamycin- and rifampicin-loaded nanospheres impregnated silicone tube for antibacterial application5
Enhanced stability of foot-and-mouth disease vaccine antigens with a novel formulation5
Intrinsic dissolution rate modeling for the pharmacopoeia apparatus rotating disk compared to flow channel method5
Drug content determination of low-dosed hot-melt extruded filaments using Raman spectroscopy5
Atorvastatin-loaded cubosome: a repurposed targeted delivery systems for enhanced targeting against breast cancer4
In vitro evaluation of enteral tube administration of lansoprazole orally disintegrating tablets4
Ten years of the manufacturing classification system: a review of literature applications and an extension of the framework to continuous manufacture4
Recent advances and persistent challenges in the design of freeze-drying process for monoclonal antibodies4
Major difference in particle size, minor difference in release profile: a case study of solid lipid nanoparticles4
Mini-tablets as technological strategy for modified release of morphine sulfate4
Transdermal drug delivery of rizatriptan using microneedles array patch: preparation, characterization and ex-vivo/in-vivo study4
Self-assembled micelles enhance the oral delivery of curcumin for the management of alcohol-induced tissue injury4
Using chitosan-coated magnetite nanoparticles as a drug carrier for opioid delivery against breast cancer4
Inhalable spray-dried polycaprolactone-based microparticles of Sorafenib Tosylate with promising efficacy on A549 cells4
An overview on the advantages and limitations of 3D printing of microneedles4
Preparation and characterization of duloxetine-loaded nanofiber scaffold composed of polyvinyl alcohol and chitosan as wound healing agent, fabricated by electrospinning method4
Review of industrially recognized polymers and manufacturing processes for amorphous solid dispersion based formulations4
Docetaxel liposomes for lung targeted delivery: development and evaluation4
Microsponges-mediated targeted topical delivery of rosemary oil for hair growth promotion: optimization and in-vivo studies4
Caspofungin formulations for buccal and sublingual mucosae anti-fungal infections: physicochemical characterization, rheological analysis, release and ex vivo permeabili4
Surface Modification of lactose carrier particles using a fluid bed coater to improve fine particle fraction for dry powder inhalers3
Formulation development and evaluation of push-pull osmotic pump bi-layered tablets for phencynonate HCl in the treatment of motion sickness3
Recent advances in targeting malaria with nanotechnology-based drug carriers3
Co-crystallization of Hesperidin with different co-formers to enhance solubility, antioxidant and anti-inflammatory activities3
Formulation and evaluation of carrier-based dry powders containing budesonide and arformoterol for inhalation therapy3
Revolutionizing treatment for topical fungal infections: evaluating penetration-enhancer-containing vesicles as a fluconazole delivery system: Ex-vivo and 3
Nanoparticles as carriers of photosensitizers to improve photodynamic therapy in cancer3
Long-acting release of fluocinolone acetonide microspheres using electrospray technology for noninfectious uveitis therapy3
Quercetin nanocrystals stabilized by glycyrrhizic acid for liver targeted drug delivery: impact of glycyrrhizic acid concentrations3
Preparation, characterisation and pharmacokinetics evaluation of dry power inhalation formulations of polymyxin B3
Ectoine gel transdermal formulation as a novel therapeutic approach in melanoma using 3D printed microneedles3
Preparation, characterization, and anti-colon cancer activity of oridonin-loaded long-circulating liposomes3
Preparation and characterisation of esculetin-loaded nanostructured lipid carriers gels for topical treatment of UV-induced psoriasis3
Preparation of an isorhamnetin phospholipid complex for improving solubility and anti-hyperuricemia activity3
Characterization and ex vivo evaluation of curcumin nanoethosomes for melanoma treatment3
Perspective on the influence of suspension manufacturing unit operations on bioburden viability and selection of sampling points at the pilot scale3
Green polymer altered in-situ gel oral liquid sustainable release preparation of vildagliptin suitable for dysphagic diabetic patients: assessment in-vitro & in-vivo3
Correction3
Impact of critical process parameters on the dimensional, mean weight, and swelling properties of 3D-printed intravaginal rings: a quality by design approach3
Surface modifications of gold nanoparticles: stabilization and recent applications in cancer therapy3
Enhancing ocular drug delivery: development and in vivo evaluation of mucoadhesive nanostructured lipid carriers for terbinafine3
Permeation, stability and acute dermal irritation of miroestrol and deoxymiroestrol from Pueraria candollei var. mirifica crude extract loaded transdermal gels3
A study on distribution and stability of drugs at the interface of a scutellarin-loaded emulsion3
Fast dissolving microneedle patch for pronounced systemic delivery of an antihyperlipidemic drug3
Hyaluronic acid/lactoferrin–coated polydatin/PLGA nanoparticles for active targeting of CD44 receptors in lung cancer3
Novel bioequivalent oral disintegrating tablet of aripiprazole prepared by direct compression technique with shortened disintegration time3
pH-sensitive chitosan-deoxycholic acid/alginate nanoparticles for oral insulin delivery3
Engineering orally disintegrating tablets for buccal delivery of cilostazol with enhanced dissolution and bioavailability: a novel dual porogenic approach, in vitro char3
Application of a novel multicomponent nanoemulsion to tumor therapy Based on the theory of “unification of drugs and excipients”3
Optimization of a solidified micelle formulation for enhanced oral bioavailability of atorvastatin calcium using statistical experimental design3
Development of thermosensitive liposome-containing in-situ gel systems for intranasal administration of thiocolchicoside and in vivo evaluation in a rabbit model3
Different applications of temperature responsive nanogels as a new drug delivery system mini review3
Preparation of tofacitinib sustained-release tablets using hot melt extrusion technology3
‘Applications of machine learning in liposomal formulation and development’2
Fabrication of gastro-floating sustained-release etoricoxib and famotidine tablets: design, optimization , in-vitro , and in-vivo evaluati2
Design, fabrication, and in vitro-in vivo evaluation of surface-engineered pyrazinamide-loaded lipid nanoparticles for tuberculosis therapy2
Nanonized carbamazepine for nose-to-brain delivery: pharmaceutical formulation development2
Injectable testosterone PLGA microsphere with different characteristics: effect of preparation method (paddle mixing versus microfluidic device)2
Chitosan-bovine serum albumin-Carbopol 940 nanogels for mupirocin dermal delivery: ex-vivo permeation and evaluation of cellular binding capacity via radiolabeling2
Effect of strength and porosity of tablets on the magnitudes of subdivision forces2
Novel dapagliflozin di-L-proline cocrystal-loaded tablet: preparation, physicochemical characterization, and pharmacokinetics in beagle dogs and mini-pigs2
Development and optimization of oral nanoemulsion of rutin for enhancing its dissolution rate, permeability, and oral bioavailability2
Comparative study on the performance of monoolein cubic nanoparticles and trimyristin solid lipid nanoparticles as carriers for docetaxel2
Thermoresponsive lipids engineered magnetic nanoparticles for spatiotemporal delivery of hesperidin to inflammatory sites in animal model2
Preparation and characterization of a hydroxypropyl methylcellulose based wafer for simultaneous delivery of phenytoin and insulin as wound dressing material2
Electrospun PVA nanofiber mat for topical Deflazacort delivery: accentuated anti-inflammatory efficacy for wound healing2
Development of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation2
The electronic tongue: an advanced taste-sensing multichannel sensory tool with global selectivity for application in the pharmaceutical and food industry2
Pharmacy Education, Science, and Practice Conference 2025 Supplement Part B2
Intranasal bilosomes in thermosensitive hydrogel: advancing desvenlafaxine succinate delivery for depression management2
Studies on pomegranate seed oil enriched galantamine hydrobromide microemulsion: formulation, in vitro antioxidant and neuroprotective potential2
Loading Pistacia atlantica essential oil in solid lipid nanoparticles and its effect on apoptosis of breast cancer cell line MDA-MB-2312
Development of posaconazole nanocrystalline solid dispersion: preparation, characterization and in vivo evaluation2
Dexibuprofen enteric film-coated tablets: design, characterization and pharmacokinetic analysis in human volunteers2
Impact of surfactant raw material variability on extrudate clarity appearance (transparency) in HME continuous manufacturing2
Fabrication and in vitro characterization of zinc oxide nanoparticles and hyaluronic acid-containing carboxymethylcellulose gel for wound healing application2
Improved direct compression properties of Gardeniae fructus water extract powders via fluid bed-mediated surface engineering2
Intravenous delivery of furosemide using lipid-based versus polymer-based nanocapsules: in vitro and in vivo studies2
Engineering nanosystems for transdermal delivery of antihypertensive drugs2
The synthesis of broccoli sprout extract-loaded silk fibroin nanoparticles as efficient drug delivery vehicles: development and characterization2
mPEG-Cholic acid/TPGS mixed micelles for combined delivery of paclitaxel and bufalin to treat hepatocellular carcinoma2
Inhibition of growth and lung metastasis of breast cancer by pH-responsive methotrexate/curcumin-loaded chitosan-stabilized nanoemulsions2
Recent progress in nanoparticulate-based intranasal delivery for treating of different central nervous system diseases2
Hydrolysis kinetics of the prodrug myristyl nicotinate2
Spray dried polymyxin B liposome for inhalation against gram-negative bacteria2
Bilayer nanofibrous wound dressing prepared by electrospinning containing gallic acid and quercetin with improved biocompatibility, antibacterial, and antioxidant effects2
Thermoresponsive biomaterial system of irinotecan and curcumin for the treatment of colorectal cancer: in-vitro and in-vivo investigations2
Covalently coupling doxorubicin to polymeric nanoparticles as potential inhaler therapy:in vitrostudies2
Hyperoside-loaded TPGs/mPEG-PDLLA self-assembled polymeric micelles: preparation, characterization and in vitro/in vivo evaluation2
Combination immunotherapy of PEG-modified preladenant thermosensitive liposomes and PD-1 inhibitor effectively enhances the anti-tumor immune response and therapeutic effects2
Peptide-functionalized gold nanoparticles for boron neutron capture therapy with the potential to use in Glioblastoma treatment2
In vitro evaluation and in vivo efficacy studies of a liposomal doxorubicin-loaded glycyrretinic acid formulation for the treatment of hepatocellular 2
Intensification of quercetin nanobubble formulation and performance by multi-factor optimization and interaction analysis2
Nanoformulated fenbendazole as an attractive approach for treating neurocysticercosis: in vitro and in vivo studies2
Feasibility of developing hospital preparation by semisolid extrusion 3D printing: personalized amlodipine besylate chewable tablets2
Data-driven approach to mitigate quality impact of hygroscopic pharmaceutical raw materials throughout the supply chain2
Effects of tableting process parameters and powder lubrication levels on tablet surface temperature and moisture content2
Targeted drug delivery via folate decorated nanocarriers based on linear polymer for treatment of breast cancer2
Delivery of a therapeutic antibody to the lower gastrointestinal tract for the treatment of Clostridium difficile infection (CDI)2
Ritonavir nanosuspensions prepared by microfluidization with enhanced solubility and desirable immunological properties2
Ocular polymeric nanomicelles for the posterior eye segment in the management of retinoblastoma: formulation, optimization, in vitro and ex vivo 2
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