OOIR: Observatory of International Research

Papers

(The H4-Index of Organic Process Research & Development is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Development of Versatile Routes for the Preparation of an Intermediate to Immuno-Oncology Agonist BMS-986299	147
Issue Editorial Masthead	94
Development of the Enabling Route for a Novel HCV NS3/4A Inhibitor, Furaprevir	79
Deracemization via Periodic and Non-periodic Temperature Cycles: Rationalization and Experimental Validation of a Simplified Process Design Approach	76
Issue Publication Information	57
Green Chemistry Articles of Interest to the Pharmaceutical Industry	53
Three-Step One-Pot Process of 3-Methyl-5-Benzofuranol from Amine, Aldehydes, and p-Benzoquinone	52
Binary Solvent Swap Processing in a Bubble Column in Batch and Continuous Modes	48
Importance of Thermal Stability Data to Avoid Dangerous Reagents: Temozolomide Case Study	44
Improved Acylation of Pseudoproline: Masked Threonine in Flow Peptide Chemistry	42
Issue Editorial Masthead	42
Development of a Practical and Scalable Synthetic Route for the Adenosine Monophosphate-Activated Protein Kinase Activator, ASP4132	40
Development of an Optimized Synthetic Process for an Antiobesity Drug Candidate (S-234462) Featuring Mild Chlorination of Benzoxazolone and In Situ IR Monitoring of a Mitsunobu Reaction	39
Scaling up a C–H Borylation: Addressing the Safety Concerns of an Iridium-Catalyzed Process for Multikilo Scale Manufacture	38
Issue Publication Information	35
Polymorphs, Particle Size, and a Pandemic: Development of a Scalable Crystallization Process for Molnupiravir, an Antiviral for the Treatment of COVID-19	34
Consolidating and Managing Data for Drug Development within a Pharmaceutical Laboratory: Comparing the Mapping and Reporting Tools from Software Applications	34
Issue Publication Information	33
Reduction in the Thermal Stability of Nitro-Containing Compounds due to Cross-Catalyzed Autocatalytic Decomposition Caused by Nitro-Containing Impurities	32
In Support of Early-Career Researchers	32
Issue Publication Information	31
Implementation of MSMPR Crystallization to Avoid Liquid–Liquid Phase Separation	30
Biocatalysis: Improving Enzymatic Processes through Protein and Reaction Engineering	30
Synthesis of BACE1 Inhibitors E2609/E2071 via Oxime–Olefin Cycloaddition Following a Process Risk Mitigation Strategy	30
Process Development of Tacalcitol	30

Initial Route Scouting and Final Process Development for the Multi-Kg Production of 3-Fluoro-6-methoxyquinoline from p-Anisidine and 2-Fluoromalonic Acid	30
Some Items of Interest to Process R&D Chemists and Engineers	30
Issue Editorial Masthead	29
Issue Publication Information	29