Journal of Biomedical Optics

Papers
(The median citation count of Journal of Biomedical Optics is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Intraoperative characterization of cardiac tissue: the potential of light scattering spectroscopy68
Comparative analysis of intraoperative thermal and optical imaging for identification of the human primary sensory cortex66
Structured light imaging mesoscopy: detection of embedded morphological changes in superficial tissues61
ALA-based photodynamic priming in murine skin increases blood flow and oxygenation52
Dual division of focal plane polarimeters-based collinear reflection Mueller matrix fast imaging microscope49
Phasor-based FLIM analysis of NAD(P)H and FAD autofluorescence for label-free bacterial classification44
Automatic correction of motion artifact in dynamic contrast-enhanced fluorescence imaging during open orthopedic surgery39
Introduction to Special Issue on Metabolic Imaging and Spectroscopy, 202536
Er:YAG laser biofilm removal from zero-gap periodontal/peri-implant model system mimicking clinical attachment loss36
Imaging lymphatic function and inflammation response through hypoxia via endogenous biomarker34
Assessment of nonalcoholic fatty liver function by photoacoustic imaging32
Remote and low-cost intraocular pressure monitoring by deep learning of speckle patterns30
Deep-learning–based optical coherence tomography reconstruction for high-speed and contrast morphology and vasculature imaging30
Generalized 3D registration algorithm for enhancing retinal optical coherence tomography images30
Polarized hyperspectral and polarized light microscopic imaging for enhanced visualization of white blood cells29
Characterization of vascular patterns in endometrial cancer via optical resolution photoacoustic microscopy29
In vivo hamster cheek pouch subepithelial ablation, biomaterial injection, and localization: pilot study28
Monte Carlo simulation of the effect of melanin concentration on light–tissue interactions for transmittance pulse oximetry measurement26
Wide dynamic range measurement of blood flow in vivo using laser speckle contrast imaging25
Improved spatial speckle contrast model for tissue blood flow imaging: effects of spatial correlation among neighboring camera pixels25
Effects of phantom microstructure on their optical properties24
Blood component analysis using mid-infrared photoacoustic spectroscopy based on ultrasound detection: glucose analysis trial24
Approaching closed spherical, full-view detection for photoacoustic tomography24
Hyperspectral imaging of 4T1 mammary carcinomas grown in dorsal skinfold window chambers: spectral renormalization and fluorescence modeling23
Polarization-insensitive optical coherence tomography using pseudo-depolarized reference light for mitigating birefringence-related image artifacts23
Difference imaging from single measurements in diffuse optical tomography: a deep learning approach22
Tissue harvest with a laser microbiopsy (Erratum)22
Enhanced resolution optoacoustic microscopy using a picosecond high repetition rate Q-switched microchip laser22
Solid optical tissue phantom tools based on upconverting nanoparticles for biomedical applications22
Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems22
Stain-free enucleation of mouse and human oocytes with a 1033 nm femtosecond laser21
Influence of optical aberrations on depth-specific spatial frequency domain techniques21
Special Section Guest Editorial: Introduction to the Special Section Celebrating 30 years of Open Source Monte Carlo Codes in Biomedical Optics21
Multiplexed optical fiber cell temperature sensing system with high sensitivity and accuracy21
Depolarization diagrams for circularly polarized light scattering for biological particle monitoring20
Spatial analysis of polarimetric images to enhance near-surface sampling sensitivity: feasibility in demineralized teeth and other tissue-like media19
All-reflective tethered capsule endoscope for multimodal optical coherence tomography in the esophagus19
Multimodal microscope for optical coherence microscopy, tomography, vibrometry, and two-photon microscopy in the living mouse cochlea19
Noninvasive assessment of skin barrier function: evaluating ceramide-based moisturizer using confocal Raman spectroscopy19
Assessing spectral effectiveness in color fundus photography for deep learning classification of retinopathy of prematurity18
Minimizing near-infrared autofluorescence in preclinical imaging with diet and wavelength selection18
Meshless Monte Carlo radiation transfer method for curved geometries using signed distance functions18
3D-motion mapping of the malleus–incus complex using a robot-mounted optical coherence tomography vibrometry system17
Spectral correction of light emitting diodes enables accurate hydration ratio calculation using narrowband diffuse reflectance spectroscopy16
Laser absorption spectroscopy measurements of different pulmonary oxygen gas concentrations in transmittance and remittance geometry: phantom study16
Scattering angle resolved optical coherence tomography measures morphological changes in Bacillus subtilis colonies16
Deep learning-based optical approach for skin analysis of melanin and hemoglobin distribution16
Noninvasive detection and prediction method for temperature in ex vivo biological tissue based on opto-thermal-acoustic co-coupling16
Photoacoustic imaging plus X: a review16
Deep structural brain imaging via computational three-photon microscopy16
Structure of tendon causes highly optical anisotropic properties and transport16
Evaluating clinical near-infrared surgical camera systems with a view to optimizing operator and computational signal analysis15
Noise insensitive volumetric fusion method for enhanced photoacoustic microscopy15
Automated three-dimensional image registration for longitudinal photoacoustic imaging15
Retrieval of chromophore concentration changes in a digital human head model using analytical mean partial pathlengths of photons15
Automatic granular and spinous epidermal cell identification and analysis on in vivo reflectance confocal microscopy images using cell morphological features15
Comparison of minimal detectable protoporphyrin IX concentrations with a loupe device and conventional 5-ALA fluorescence microscopy: an experimental study14
Short-wave infrared (SWIR) spectroscopy and imaging of biological tissues: a decade of advancements (2016-2025)14
Hybrid CNN–transformer demosaicing for bioinspired single-chip color-near-infrared fluorescence imaging in oncologic surgery14
Direct three-dimensional segmentation of prostate glands with nnU-Net14
Multi-exposure speckle imaging through an optical fiber bundle14
CellSNAP: a fast, accurate algorithm for 3D cell segmentation in quantitative phase imaging14
Characterization of bacteria swarming effect under plasmonic optical fiber illumination14
Optical coherence tomography–enabled classification of the human venoatrial junction13
Development of a statistically standardized optical digital wrist model through integrated MRI-diffuse optical imaging methodology13
Evaluating backscattering polarized light imaging microstructural mapping capabilities through neural tissue and analogous phantom imaging13
Reflective optical imaging for scattering medium using chaotic laser13
Circularly polarized light scattering imaging of a cancerous layer creeping under a healthy layer for the diagnosis of early-stage cervical cancer13
Deep learning-based spectroscopic single-molecule localization microscopy13
Photoacoustic imaging on its way toward clinical utility: a tutorial review focusing on practical application in medicine13
Emerging uses of 5-aminolevulinic-acid-induced protoporphyrin IX in medicine: a review of multifaceted, ubiquitous, molecular diagnostic, therapeutic, and theranostic opportunities13
Intravital photoacoustic brain stimulation with high-precision13
Two-step regression analysis approach to assess burn wound severity using spatial frequency domain imaging13
Development of a shortwave infrared sinuscope for the detection of cerebrospinal fluid leaks13
LED-based multicolor extended resolution transmission fluorescence microscopy13
Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array13
Clinical PDT dose dosimetry for pleural Photofrin-mediated photodynamic therapy12
Development of breast-mimicking phantoms for use in optical coherence elastography12
Perspective on the optics of medical imaging12
Beyond light scattering: the effects of intralipid on benzoporphyrin derivative-sensitized photodynamic treatment in ovarian cancer cells12
Design and validation of a high-speed hyperspectral laparoscopic imaging system12
Label-free imaging flow cytometry for cell classification based directly on multiple off-axis holographic projections12
Assessment of open-field fluorescence guided surgery systems: implementing a standardized method for characterization and comparison12
Lightweight and precise cell classification based on holographic tomography-derived refractive index point cloud12
Toward fluorescence digital twins: multi-parameter experimental validation of fluorescence Monte Carlo simulations using solid phantoms12
Impact of sample handling protocols on soft tissue attenuation coefficient and morphology12
Flexible catheter optical coherence tomography of the porcine middle ear via the Eustachian tube using a 3D-printed reflective objective12
Monte Carlo simulation platform for laser Doppler flowmetry11
Motion-resistant three-wavelength spatial frequency domain imaging system with ambient light suppression using an 8-tap CMOS image sensor11
Enhanced neuroimaging with a calcium sensor in ex-vivo Drosophila melanogaster brains using closed-loop adaptive optics light-sheet fluorescence microscopy11
Non-invasive assessment of sublingual microcirculation using flow derived from green light PPG: evaluation and reference values11
Influence mechanism of the temporal duration of laser irradiation on photoacoustic technique: a review11
Restoration of metabolic functional metrics from label-free, two-photon human tissue images using multiscale deep-learning-based denoising algorithms11
Two-stage classification strategy for breast cancer diagnosis using ultrasound-guided diffuse optical tomography and deep learning11
New Year, New JBO Editor-in-Chief11
Wavefront shaping improves the transparency of the scattering media: a review (Publisher’s Note)11
Hyperspectral dark-field microscopy of human breast lumpectomy samples for tumor margin detection in breast-conserving surgery11
Incremental residual polarization caused by aging in human skin11
Polarimetric analysis of the Alzheimer’s pathology in excised mouse brain tissue11
Motion-artifact-free single shot two-beam optical coherence elastography system11
Utilizing convolutional neural networks for discriminating cancer and stromal cells in three-dimensional cell culture images with nuclei counterstain11
Improved 3D image reconstruction via deep-learning-based fusion of light-field microscopy and Fourier light-field microscopy images11
Imaging the ex-vivo human cochlea using 1.3-μm and 1.7-μm optical coherence tomography11
Two-stage diffuse fluorescence tomography for monitoring of drug distribution in photodynamic therapy of tumors11
Honoring Lihong V. Wang, a pioneer in biomedical optics10
Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling10
Quantitative estimation of optical properties in bilayer media within the subdiffusive regime using a tilted fiber-optic probe in diffuse reflectance spectroscopy, part 1: a theoretical framework for 10
Hardware-software co-design of an open-source automatic multimodal whole slide histopathology imaging system10
Photoplethysmographic imaging and analysis of pulsatile pressure wave in palmar artery at 10 wavelengths10
HyperTRCSS: A hyperspectral time-resolved compressive sensing spectrometer for depth-sensitive monitoring of cytochrome-c-oxidase and blood oxygenation10
Asynchronous optical coherence elastography and directional phase gradient analysis10
Terahertz Mie scattering in tissue: diffuse polarimetric imaging and Monte Carlo validation in highly attenuating media models10
Scaling down the dimensions of a Fabry–Perot polymer film acoustic sensor for photoacoustic endoscopy10
Perspective on the use of fluorescence molecular imaging for peripheral and deep en face margin assessment10
Photoacoustic and fluorescence dual-modality imaging of cerebral biomarkers in Alzheimer’s disease rodent model10
Noninvasive continuous blood pressure prediction using FlexNIRS and machine learning during carotid endarterectomy10
Perioperative diffuse optical imaging of blood flow distributions for porcine skin flap viability assessment10
Comparison of diffuse correlation spectroscopy analytical models for measuring cerebral blood flow in adults10
Depth-dependent fluence compensation without a priori knowledge of tissue composition for quantitative ultrasound-guided photoacoustic imaging10
Exploring near-infrared autofluorescence properties in parathyroid tissue: an analysis of fresh and paraffin-embedded thyroidectomy specimens10
Transmission infrared micro-spectroscopic study of individual human hair10
Mapping functional hemodynamic and metabolic responses to dementia: a broadband spectroscopy pilot study10
Quantitative evaluation of the site-dependent cell viability in three-dimensional hepatocyte spheroids based on dynamic optical coherence tomography9
Wavefront shaping improves the transparency of the scattering media: a review9
Combined frequency domain near-infrared spectroscopy and diffuse correlation spectroscopy system for comprehensive metabolic monitoring of inspiratory muscles during loading9
Femtosecond laser-assisted selective holding with ultra-low power for direct manipulation of biological species9
Evaluating blue light impact on reconstructed human epidermis using laser speckle imaging9
Structurally constrained and pathology-aware convolutional transformer generative adversarial network for virtual histology staining of human coronary optical coherence tomography images9
Two-color fluorescence-guided surgery for head and neck cancer resections9
Field programmable gate array compression for large array multispeckle diffuse correlation spectroscopy9
Remote sensing of alcohol consumption using machine learning speckle pattern analysis9
Radiometric and spectral characterization of multipanel planar light-emitting devices: a generalizable irradiance mapping approach for dose estimation9
Diffuse optical tomography system for acute traumatic brain injury in the intensive care unit: a prospective study on healthy volunteers9
Relationship between depth-wise refractive index and biomechanical properties of human articular cartilage9
Learnable real-time inference of molecular composition from diffuse spectroscopy of brain tissue9
Light sources and detectors: applications in nanoscale imaging, sensing, and actuation9
3D photogrammetry quantifies the size of basal cell carcinoma lesions with submillimeter accuracy: high correlation with lesion response to photodynamic therapy9
Impact of image preprocessing on dermatological OCTA vessel segmentation: a DERMA-OCTA study9
Depth detection limit of a fluorescent object in tissue-like medium with background emission in continuous-wave measurements: a phantom study9
Off-axis digital lensless holographic microscopy based on spatially multiplexed interferometry9
Noninvasive holographic sensor system for measuring stiffness of soft micro samples9
NIRFASTerFF: an accessible, cross-platform Python package for fast photon modeling8
Patient-specific arterial input function for accurate perfusion assessment in intraoperative fluorescence imaging8
AI-powered remote monitoring of brain responses to clear and incomprehensible speech via speckle pattern analysis8
Convolutional neural network advances in demosaicing for fluorescent cancer imaging with color–near-infrared sensors8
Hyperspectral imaging in neurosurgery: a review of systems, computational methods, and clinical applications8
Effective transfer of tumor annotations from hematoxylin and eosin to fluorescence images of breast and lung tissues8
Optical intensity changes under static load and their dependence on dental implant design around bone-mimicking material8
Convolutional neural network-based regression analysis to predict subnuclear chromatin organization from two-dimensional optical scattering signals8
Deep-learning approach to stratified reconstructions of tissue absorption and scattering in time-domain spatial frequency domain imaging8
Real-time identification of life-threatening necrotizing soft-tissue infections using indocyanine green fluorescence imaging8
Combined optical-electromechanical wearable sensors for cardiac health monitoring8
Monte Carlo simulation of spatial frequency domain imaging for breast tumors during compression8
Deep learning segmentation of periarterial and perivenous capillary-free zones in optical coherence tomography angiography8
Fast and robust Fourier ptychographic microscopy with position misalignment correction8
In vivo tumor imaging of pre-clinical models via reflection-mode measurements of circular degree of polarization8
Efficient quality control of platelet-rich plasma preparation using computer vision and deep learning8
Adaptive correction method of hybrid aberrations in Fourier ptychographic microscopy8
Model for the diffuse reflectance in spatial frequency domain imaging (Erratum)8
Comprehensive framework of GPU-accelerated image reconstruction for photoacoustic computed tomography8
Near-infrared light-induced transcranial photobiomodulation enhances the visual pathway’s function in healthy volunteers8
Real-time fidelity assessment of fluorescence molecular imaging without reference images8
Development and preclinical evaluation of an endonasal Raman spectroscopy probe for transsphenoidal pituitary adenoma surgery8
Evaluation of analytical models to estimate depth of fluorescence objects in biological media8
Förster resonance energy transfer efficiency measurements on vinculin tension sensors at focal adhesions using a simple and cost-effective setup8
Elucidating the effect of tumor and background region-of-interest selection on the performance metrics used to assess fluorescence imaging8
Cherenkov light emission in external beam radiation therapy of the larynx8
Collagen microarchitecture from polarized light imaging: a biomechanics perspective8
Local protein detection with lateral flow assay read through tissue using X-ray excited luminescence chemical imaging8
Basis function model to extract the combined confocal and fall-off function from multiple optical coherence tomography A-scans8
Robust, high-density lesion mapping in the left atrium with near-infrared spectroscopy8
Quantitative estimation of optical properties in bilayer media within the subdiffusive regime using tilted fiber-optic probe diffuse reflectance spectroscopy, part 2: probe design, realization, and ex8
Single-distance and dual-slope frequency-domain near-infrared spectroscopy to assess skeletal muscle hemodynamics8
DOT-AE-GAN: a hybrid autoencoder–GAN model for enhanced ultrasound-guided diffuse optical tomography reconstruction8
Detection of breast cancer using machine learning on time-series diffuse optical transillumination data7
Rolling shutter-resistant confocal endomicroscopy image stitching via dual-path Gaussian U-Net7
Detection properties of indium-111 and IRDye800CW for intraoperative molecular imaging use across tissue phantom models7
Improved in vivo optical coherence tomography imaging of animal peripheral nerves using a prism nerve holder7
Compact and ultracompact spectral imagers: technology and applications in biomedical imaging7
Ninety years of pulse oximetry: history, current status, and outlook7
Optimizing optical coherence tomography to detect occult spermatozoa in rat testis after induced non-obstructive azoospermia7
Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer’s disease7
Quantitative phase imaging techniques for measuring scattering properties of cells and tissues: a review—part I7
Impact of corpus callosum fiber tract crossing on polarimetric images of human brain histological sections: ex vivo studies in transmission configuration7
Improved U-net-based leukocyte segmentation method7
Deep-learning-based cross-modality translation from Stokes image to bright-field contrast7
Compact and cost-effective laser-powered speckle contrast optical spectroscopy fiber-free device for measuring cerebral blood flow7
Targeted multispectral filter array design for the optimization of endoscopic cancer detection in the gastrointestinal tract7
Integration of cellular-resolution optical coherence tomography and Raman spectroscopy for discrimination of skin cancer cells with machine learning7
Customizable optical tissue phantom platform for characterization of fluorescence imaging device sensitivity7
Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW7
Quantitative second harmonic generation microscopy for characterizing collagen remodeling in papillary thyroid carcinoma7
Improving diffuse optical tomography imaging quality using APU-Net: an attention-based physical U-Net model6
Evaluation of layered tissue scattering properties: a time-domain spatially resolved spectroscopy approach6
X-ray Cherenkov-luminescence tomography reconstruction with a three-component deep learning algorithm: Swin transformer, convolutional neural network, and locality module6
Considerations for the use of targeted fluorescence contrast agents to detect circulating cancer cell populations with diffuse in vivo flow cytometry6
Multiwavelength tissue-mimicking phantoms with tunable vessel pulsation6
Protoporphyrin IX delayed fluorescence imaging: a modality for hypoxia-based surgical guidance6
Light-guided dynamic phantom to mimic microvasculature for biomedical applications: an exploration for pulse oximeter6
Assessing the effects of prenatal poly-drug exposure on fetal brain vasculature using optical coherence angiography6
Depth-dependent attenuation and backscattering characterization of optical coherence tomography by stationary iterative method6
Enhancing intraoperative tumor delineation with multispectral short-wave infrared fluorescence imaging and machine learning6
Accuracy and precision of depth-resolved estimation of attenuation coefficients in optical coherence tomography6
Neighbor-based adaptive sparsity orthogonal least square for fluorescence molecular tomography6
Fiftieth anniversary of fiber optic–based fluorometry of brain mitochondrial NADH redox state monitored in vivo6
Polarized hyperspectral microscopic imaging system for enhancing the visualization of collagen fibers and head and neck squamous cell carcinoma6
Macroscopic inelastic scattering imaging using a hyperspectral line-scanning system identifies invasive breast cancer in lumpectomy and mastectomy specimens6
Increased fluorescence observation intensity during the photodynamic diagnosis of deeply located tumors by fluorescence photoswitching of protoporphyrin IX6
Acoustic resolution photoacoustic Doppler flowmetry for assessment of patient rectal cancer blood perfusion6
Bubble dynamics and speed of jets for needle-free injections produced by thermocavitation6
Large field-of-view short-wave infrared metalens for scanning fiber endoscopy6
Reconstruction of fluorophore absorption and fluorescence lifetime using early photon mesoscopic fluorescence molecular tomography: a phantom study6
Challenges and advances in two-dimensional photoacoustic computed tomography: a review6
Frameworks of wavelength selection in diffuse reflectance spectroscopy for tissue differentiation in orthopedic surgery6
Mueller matrix analysis of a biologically sourced engineered tissue construct as polarimetric phantom6
Machine learning–based classification of spatially resolved diffuse reflectance and autofluorescence spectra acquired on human skin for actinic keratoses and skin carcinoma diagnostics aid6
Deep-learning–enabled spatial frequency domain imaging of the spatiotemporal dynamics of skin physiology6
Advancing infantile hemangioma diagnosis by integrating temperature, color, and texture6
Affordable miniaturized speckle contrast diffuse correlation tomography device for depth-sensitive mapping of cerebral blood flow in rodents6
Subcellular analysis of nuclear and cytoplasmic redox indices differentiates breast cancer cell subtypes better than nuclear-to-cytoplasmic area ratio6
Margin assessment during breast conserving surgery using diffuse reflectance spectroscopy6
Self-calibrated pulse oximetry algorithm based on photon pathlength change and the application in human freedivers6
Brillouin microscopy in cancer research: a review6
Transport-of-intensity phase imaging using commercially available confocal microscope6
Spectral analysis of multiple scattering factors of turbid media for glucose measurement using near-infrared spectroscopy6
Robust lumen segmentation based on temporal residual U-Net using spatiotemporal features in intravascular optical coherence tomography images6
Near-infrared imaging of head and neck squamous cell carcinoma using indocyanine green that targets the αvβ6 peptide6
Color-filter-array-based multispectral photoplethysmography optical sensor and its motion artifact correction algorithm (Erratum)6
Can diffuse reflectance spectroscopy identify shuntodynia in pediatric hydrocephalus patients?6
ArthroNavi framework: stereo endoscope-guided instrument localization for arthroscopic minimally invasive surgeries6
Photoacoustic imaging of the dynamics of a dye-labeled IgG4 monoclonal antibody in subcutaneous tissue reveals a transient decrease in murine blood oxygenation under anesthesia6
Determination of tissue oxygen saturation by diffuse reflectance spectroscopy6
Measuring and imaging of transcutaneous bilirubin, hemoglobin, and melanin based on diffuse reflectance spectroscopy6
Dual SwinUNet architecture for enhanced photoacoustic imaging: a contrastive learning approach in image and sinogram domains6
JBO 2024 List of Reviewers6
Rapid inverse radiative transfer solver for multiparameter spectrophotometry without integrating sphere6
Tetherless miniaturized point detector device for monitoring cortical surface hemodynamics in mice6
Multifocal acoustic radiation force-based reverberant optical coherence elastography for evaluation of ocular globe biomechanical properties6
Multivariate analysis of breast tissue using optical parameters extracted from a combined time-resolved fluorescence and diffuse reflectance system for tumor margin detection6
Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics 6
Subsurface fluorescence time-of-flight imaging using a large-format single-photon avalanche diode sensor for tumor depth assessment6
Integrating optical coherence tomography and bioluminescence with predictive modeling for quantitative assessment of methicillin-resistant S. aureus biofilms6
Multiplane HiLo microscopy with speckle illumination and non-local means denoising5
Development of Pluoronic nanoparticles of fluorocoxib A for endoscopic fluorescence imaging of colonic adenomas5
Quantitative assessment of rheumatoid arthritis treatment response using short-wave infrared hyperspectral imaging soft abundance scoring5
Assessment of the activity of secondary caries lesions with short-wavelength infrared, thermal, and optical coherence tomographic imaging5
Development of hydrogel-based standards and phantoms for non-linear imaging at depth5
Evaluating feasibility of functional near-infrared spectroscopy in dolphins5
Vibrational imaging of metabolites for improved microbial cell strains5
Spatiotemporal image reconstruction to enable high-frame-rate dynamic photoacoustic tomography with rotating-gantry volumetric imagers5
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