Journal of Biomedical Optics

Papers
(The median citation count of Journal of Biomedical Optics is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Intraoperative characterization of cardiac tissue: the potential of light scattering spectroscopy66
Comparative analysis of intraoperative thermal and optical imaging for identification of the human primary sensory cortex62
Structured light imaging mesoscopy: detection of embedded morphological changes in superficial tissues55
ALA-based photodynamic priming in murine skin increases blood flow and oxygenation49
Phasor-based FLIM analysis of NAD(P)H and FAD autofluorescence for label-free bacterial classification42
Dual division of focal plane polarimeters-based collinear reflection Mueller matrix fast imaging microscope42
Automatic correction of motion artifact in dynamic contrast-enhanced fluorescence imaging during open orthopedic surgery35
Introduction to Special Issue on Metabolic Imaging and Spectroscopy, 202534
Er:YAG laser biofilm removal from zero-gap periodontal/peri-implant model system mimicking clinical attachment loss34
Imaging lymphatic function and inflammation response through hypoxia via endogenous biomarker33
Assessment of nonalcoholic fatty liver function by photoacoustic imaging32
Generalized 3D registration algorithm for enhancing retinal optical coherence tomography images29
In vivo hamster cheek pouch subepithelial ablation, biomaterial injection, and localization: pilot study29
Deep-learning–based optical coherence tomography reconstruction for high-speed and contrast morphology and vasculature imaging29
Approaching closed spherical, full-view detection for photoacoustic tomography28
Polarized hyperspectral and polarized light microscopic imaging for enhanced visualization of white blood cells28
Remote and low-cost intraocular pressure monitoring by deep learning of speckle patterns28
Monte Carlo simulation of the effect of melanin concentration on light–tissue interactions for transmittance pulse oximetry measurement27
Effects of phantom microstructure on their optical properties27
Blood component analysis using mid-infrared photoacoustic spectroscopy based on ultrasound detection: glucose analysis trial26
Characterization of vascular patterns in endometrial cancer via optical resolution photoacoustic microscopy26
Wide dynamic range measurement of blood flow in vivo using laser speckle contrast imaging24
Improved spatial speckle contrast model for tissue blood flow imaging: effects of spatial correlation among neighboring camera pixels23
Polarization-insensitive optical coherence tomography using pseudo-depolarized reference light for mitigating birefringence-related image artifacts23
Meshless Monte Carlo radiation transfer method for curved geometries using signed distance functions23
Difference imaging from single measurements in diffuse optical tomography: a deep learning approach22
Solid optical tissue phantom tools based on upconverting nanoparticles for biomedical applications22
Spectral correction of light emitting diodes enables accurate hydration ratio calculation using narrowband diffuse reflectance spectroscopy22
Hyperspectral imaging of 4T1 mammary carcinomas grown in dorsal skinfold window chambers: spectral renormalization and fluorescence modeling22
Tissue harvest with a laser microbiopsy (Erratum)22
Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems21
Minimizing near-infrared autofluorescence in preclinical imaging with diet and wavelength selection21
Enhanced resolution optoacoustic microscopy using a picosecond high repetition rate Q-switched microchip laser20
All-reflective tethered capsule endoscope for multimodal optical coherence tomography in the esophagus20
Multimodal microscope for optical coherence microscopy, tomography, vibrometry, and two-photon microscopy in the living mouse cochlea19
Influence of optical aberrations on depth-specific spatial frequency domain techniques19
Stain-free enucleation of mouse and human oocytes with a 1033 nm femtosecond laser19
Assessing spectral effectiveness in color fundus photography for deep learning classification of retinopathy of prematurity19
Special Section Guest Editorial: Introduction to the Special Section Celebrating 30 years of Open Source Monte Carlo Codes in Biomedical Optics18
3D-motion mapping of the malleus–incus complex using a robot-mounted optical coherence tomography vibrometry system18
Deep learning-based optical approach for skin analysis of melanin and hemoglobin distribution18
Spatial analysis of polarimetric images to enhance near-surface sampling sensitivity: feasibility in demineralized teeth and other tissue-like media18
Photoacoustic imaging plus X: a review17
Multiplexed optical fiber cell temperature sensing system with high sensitivity and accuracy17
Depolarization diagrams for circularly polarized light scattering for biological particle monitoring17
Noninvasive assessment of skin barrier function: evaluating ceramide-based moisturizer using confocal Raman spectroscopy17
Automatic granular and spinous epidermal cell identification and analysis on in vivo reflectance confocal microscopy images using cell morphological features16
Scattering angle resolved optical coherence tomography measures morphological changes in Bacillus subtilis colonies16
CellSNAP: a fast, accurate algorithm for 3D cell segmentation in quantitative phase imaging16
Deep structural brain imaging via computational three-photon microscopy16
Laser absorption spectroscopy measurements of different pulmonary oxygen gas concentrations in transmittance and remittance geometry: phantom study15
Automated three-dimensional image registration for longitudinal photoacoustic imaging15
Emerging uses of 5-aminolevulinic-acid-induced protoporphyrin IX in medicine: a review of multifaceted, ubiquitous, molecular diagnostic, therapeutic, and theranostic opportunities15
Structure of tendon causes highly optical anisotropic properties and transport15
Retrieval of chromophore concentration changes in a digital human head model using analytical mean partial pathlengths of photons15
Multi-exposure speckle imaging through an optical fiber bundle15
Hybrid CNN–transformer demosaicing for bioinspired single-chip color-near-infrared fluorescence imaging in oncologic surgery15
Short-wave infrared (SWIR) spectroscopy and imaging of biological tissues: a decade of advancements (2016-2025)15
Noise insensitive volumetric fusion method for enhanced photoacoustic microscopy15
Development of a statistically standardized optical digital wrist model through integrated MRI-diffuse optical imaging methodology15
Noise-robust phase-space deconvolution for light-field microscopy14
Development of a shortwave infrared sinuscope for the detection of cerebrospinal fluid leaks14
Direct three-dimensional segmentation of prostate glands with nnU-Net14
Comparison of minimal detectable protoporphyrin IX concentrations with a loupe device and conventional 5-ALA fluorescence microscopy: an experimental study14
Characterization of bacteria swarming effect under plasmonic optical fiber illumination14
Evaluating backscattering polarized light imaging microstructural mapping capabilities through neural tissue and analogous phantom imaging14
Photoacoustic imaging on its way toward clinical utility: a tutorial review focusing on practical application in medicine14
Evaluating clinical near-infrared surgical camera systems with a view to optimizing operator and computational signal analysis14
LED-based multicolor extended resolution transmission fluorescence microscopy14
Circularly polarized light scattering imaging of a cancerous layer creeping under a healthy layer for the diagnosis of early-stage cervical cancer13
Beyond light scattering: the effects of intralipid on benzoporphyrin derivative-sensitized photodynamic treatment in ovarian cancer cells13
Deep learning-based spectroscopic single-molecule localization microscopy13
Two-step regression analysis approach to assess burn wound severity using spatial frequency domain imaging13
Impact of sample handling protocols on soft tissue attenuation coefficient and morphology13
Intravital photoacoustic brain stimulation with high-precision13
Optical coherence tomography–enabled classification of the human venoatrial junction13
Reflective optical imaging for scattering medium using chaotic laser13
Development of breast-mimicking phantoms for use in optical coherence elastography12
Design and validation of a high-speed hyperspectral laparoscopic imaging system12
Clinical PDT dose dosimetry for pleural Photofrin-mediated photodynamic therapy12
Dual-modality fluorescence lifetime imaging-optical coherence tomography intravascular catheter system with freeform catheter optics12
Perspective on the optics of medical imaging12
Label-free imaging flow cytometry for cell classification based directly on multiple off-axis holographic projections12
Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array12
Flexible catheter optical coherence tomography of the porcine middle ear via the Eustachian tube using a 3D-printed reflective objective12
Toward fluorescence digital twins: multi-parameter experimental validation of fluorescence Monte Carlo simulations using solid phantoms12
Lightweight and precise cell classification based on holographic tomography-derived refractive index point cloud12
Assessment of open-field fluorescence guided surgery systems: implementing a standardized method for characterization and comparison12
New Year, New JBO Editor-in-Chief12
Two-stage classification strategy for breast cancer diagnosis using ultrasound-guided diffuse optical tomography and deep learning11
Wavefront shaping improves the transparency of the scattering media: a review (Publisher’s Note)11
Enhanced neuroimaging with a calcium sensor in ex-vivo Drosophila melanogaster brains using closed-loop adaptive optics light-sheet fluorescence microscopy11
Two-stage diffuse fluorescence tomography for monitoring of drug distribution in photodynamic therapy of tumors11
Utilizing convolutional neural networks for discriminating cancer and stromal cells in three-dimensional cell culture images with nuclei counterstain11
Depth-dependent fluence compensation without a priori knowledge of tissue composition for quantitative ultrasound-guided photoacoustic imaging11
Scaling down the dimensions of a Fabry–Perot polymer film acoustic sensor for photoacoustic endoscopy11
Motion-resistant three-wavelength spatial frequency domain imaging system with ambient light suppression using an 8-tap CMOS image sensor11
Non-invasive assessment of sublingual microcirculation using flow derived from green light PPG: evaluation and reference values11
Hyperspectral dark-field microscopy of human breast lumpectomy samples for tumor margin detection in breast-conserving surgery11
Comparison of diffuse correlation spectroscopy analytical models for measuring cerebral blood flow in adults11
Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling11
Motion-artifact-free single shot two-beam optical coherence elastography system11
Polarimetric analysis of the Alzheimer’s pathology in excised mouse brain tissue11
Imaging the ex-vivo human cochlea using 1.3-μm and 1.7-μm optical coherence tomography11
Improved 3D image reconstruction via deep-learning-based fusion of light-field microscopy and Fourier light-field microscopy images11
Monte Carlo simulation platform for laser Doppler flowmetry11
Restoration of metabolic functional metrics from label-free, two-photon human tissue images using multiscale deep-learning-based denoising algorithms11
Asynchronous optical coherence elastography and directional phase gradient analysis10
Influence mechanism of the temporal duration of laser irradiation on photoacoustic technique: a review10
Mouthwash as a non-invasive method of indocyanine green delivery for near-infrared fluorescence dental imaging10
Perspective on the use of fluorescence molecular imaging for peripheral and deep en face margin assessment10
Detection of live breast cancer cells in bright-field microscopy images containing white blood cells by image analysis and deep learning10
Quantitative estimation of optical properties in bilayer media within the subdiffusive regime using a tilted fiber-optic probe in diffuse reflectance spectroscopy, part 1: a theoretical framework for 10
Noninvasive continuous blood pressure prediction using FlexNIRS and machine learning during carotid endarterectomy10
Two-color fluorescence-guided surgery for head and neck cancer resections10
Terahertz Mie scattering in tissue: diffuse polarimetric imaging and Monte Carlo validation in highly attenuating media models10
Incremental residual polarization caused by aging in human skin10
Honoring Lihong V. Wang, a pioneer in biomedical optics10
Hardware-software co-design of an open-source automatic multimodal whole slide histopathology imaging system10
Exploring near-infrared autofluorescence properties in parathyroid tissue: an analysis of fresh and paraffin-embedded thyroidectomy specimens10
Photoplethysmographic imaging and analysis of pulsatile pressure wave in palmar artery at 10 wavelengths9
Field programmable gate array compression for large array multispeckle diffuse correlation spectroscopy9
Quantitative evaluation of the site-dependent cell viability in three-dimensional hepatocyte spheroids based on dynamic optical coherence tomography9
Light sources and detectors: applications in nanoscale imaging, sensing, and actuation9
Evaluating blue light impact on reconstructed human epidermis using laser speckle imaging9
Photoacoustic and fluorescence dual-modality imaging of cerebral biomarkers in Alzheimer’s disease rodent model9
Structurally constrained and pathology-aware convolutional transformer generative adversarial network for virtual histology staining of human coronary optical coherence tomography images9
HyperTRCSS: A hyperspectral time-resolved compressive sensing spectrometer for depth-sensitive monitoring of cytochrome-c-oxidase and blood oxygenation9
Off-axis digital lensless holographic microscopy based on spatially multiplexed interferometry9
Age-related changes in diffuse optical tomography sensitivity profiles from childhood to adulthood9
Transmission infrared micro-spectroscopic study of individual human hair9
Mapping functional hemodynamic and metabolic responses to dementia: a broadband spectroscopy pilot study9
Noninvasive holographic sensor system for measuring stiffness of soft micro samples9
Learnable real-time inference of molecular composition from diffuse spectroscopy of brain tissue9
Relationship between depth-wise refractive index and biomechanical properties of human articular cartilage9
Deep-learning approach to stratified reconstructions of tissue absorption and scattering in time-domain spatial frequency domain imaging8
Depth detection limit of a fluorescent object in tissue-like medium with background emission in continuous-wave measurements: a phantom study8
Diffuse optical tomography system for acute traumatic brain injury in the intensive care unit: a prospective study on healthy volunteers8
Radiometric and spectral characterization of multipanel planar light-emitting devices: a generalizable irradiance mapping approach for dose estimation8
Comprehensive framework of GPU-accelerated image reconstruction for photoacoustic computed tomography8
Remote sensing of alcohol consumption using machine learning speckle pattern analysis8
Deep learning segmentation of periarterial and perivenous capillary-free zones in optical coherence tomography angiography8
Combined frequency domain near-infrared spectroscopy and diffuse correlation spectroscopy system for comprehensive metabolic monitoring of inspiratory muscles during loading8
DOT-AE-GAN: a hybrid autoencoder–GAN model for enhanced ultrasound-guided diffuse optical tomography reconstruction8
Robust, high-density lesion mapping in the left atrium with near-infrared spectroscopy8
3D photogrammetry quantifies the size of basal cell carcinoma lesions with submillimeter accuracy: high correlation with lesion response to photodynamic therapy8
Single-distance and dual-slope frequency-domain near-infrared spectroscopy to assess skeletal muscle hemodynamics8
NIRFASTerFF: an accessible, cross-platform Python package for fast photon modeling8
Patient-specific arterial input function for accurate perfusion assessment in intraoperative fluorescence imaging8
Development and preclinical evaluation of an endonasal Raman spectroscopy probe for transsphenoidal pituitary adenoma surgery8
AI-powered remote monitoring of brain responses to clear and incomprehensible speech via speckle pattern analysis8
Evaluation of analytical models to estimate depth of fluorescence objects in biological media8
Femtosecond laser-assisted selective holding with ultra-low power for direct manipulation of biological species8
Real-time identification of life-threatening necrotizing soft-tissue infections using indocyanine green fluorescence imaging8
Near-infrared light-induced transcranial photobiomodulation enhances the visual pathway’s function in healthy volunteers8
Impact of image preprocessing on dermatological OCTA vessel segmentation: a DERMA-OCTA study8
Wavefront shaping improves the transparency of the scattering media: a review8
Förster resonance energy transfer efficiency measurements on vinculin tension sensors at focal adhesions using a simple and cost-effective setup8
Monte Carlo simulation of spatial frequency domain imaging for breast tumors during compression8
Fast and robust Fourier ptychographic microscopy with position misalignment correction8
Quantitative phase imaging techniques for measuring scattering properties of cells and tissues: a review—part I7
Compact and ultracompact spectral imagers: technology and applications in biomedical imaging7
In vivo tumor imaging of pre-clinical models via reflection-mode measurements of circular degree of polarization7
Ninety years of pulse oximetry: history, current status, and outlook7
Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise7
Optimizing optical coherence tomography to detect occult spermatozoa in rat testis after induced non-obstructive azoospermia7
Hyperspectral imaging in neurosurgery: a review of systems, computational methods, and clinical applications7
Improved U-net-based leukocyte segmentation method7
Targeted multispectral filter array design for the optimization of endoscopic cancer detection in the gastrointestinal tract7
Collagen microarchitecture from polarized light imaging: a biomechanics perspective7
Rolling shutter-resistant confocal endomicroscopy image stitching via dual-path Gaussian U-Net7
Detection properties of indium-111 and IRDye800CW for intraoperative molecular imaging use across tissue phantom models7
Local protein detection with lateral flow assay read through tissue using X-ray excited luminescence chemical imaging7
Cherenkov light emission in external beam radiation therapy of the larynx7
Basis function model to extract the combined confocal and fall-off function from multiple optical coherence tomography A-scans7
Impact of corpus callosum fiber tract crossing on polarimetric images of human brain histological sections: ex vivo studies in transmission configuration7
Convolutional neural network-based regression analysis to predict subnuclear chromatin organization from two-dimensional optical scattering signals7
Improved in vivo optical coherence tomography imaging of animal peripheral nerves using a prism nerve holder7
Efficient quality control of platelet-rich plasma preparation using computer vision and deep learning7
Customizable optical tissue phantom platform for characterization of fluorescence imaging device sensitivity7
Effective transfer of tumor annotations from hematoxylin and eosin to fluorescence images of breast and lung tissues7
Optical intensity changes under static load and their dependence on dental implant design around bone-mimicking material7
Adaptive correction method of hybrid aberrations in Fourier ptychographic microscopy7
Convolutional neural network advances in demosaicing for fluorescent cancer imaging with color–near-infrared sensors7
Elucidating the effect of tumor and background region-of-interest selection on the performance metrics used to assess fluorescence imaging7
Model for the diffuse reflectance in spatial frequency domain imaging (Erratum)7
Deep-learning-based cross-modality translation from Stokes image to bright-field contrast7
Combined optical-electromechanical wearable sensors for cardiac health monitoring7
Quantitative estimation of optical properties in bilayer media within the subdiffusive regime using tilted fiber-optic probe diffuse reflectance spectroscopy, part 2: probe design, realization, and ex7
Detection of breast cancer using machine learning on time-series diffuse optical transillumination data7
Compact and cost-effective laser-powered speckle contrast optical spectroscopy fiber-free device for measuring cerebral blood flow7
Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer’s disease7
Challenges and advances in two-dimensional photoacoustic computed tomography: a review6
Subsurface fluorescence time-of-flight imaging using a large-format single-photon avalanche diode sensor for tumor depth assessment6
Special Section Guest Editorial: Tissue Phantoms to Advance Biomedical Optical Systems6
Near-infrared imaging of head and neck squamous cell carcinoma using indocyanine green that targets the αvβ6 peptide6
Advancing infantile hemangioma diagnosis by integrating temperature, color, and texture6
Looking deep inside tissue with photoacoustic molecular probes: a review6
X-ray Cherenkov-luminescence tomography reconstruction with a three-component deep learning algorithm: Swin transformer, convolutional neural network, and locality module6
Reconstruction of fluorophore absorption and fluorescence lifetime using early photon mesoscopic fluorescence molecular tomography: a phantom study6
Machine learning–based classification of spatially resolved diffuse reflectance and autofluorescence spectra acquired on human skin for actinic keratoses and skin carcinoma diagnostics aid6
Measuring and imaging of transcutaneous bilirubin, hemoglobin, and melanin based on diffuse reflectance spectroscopy6
Multiexposure laser speckle contrast analysis system calibration limited by perfusion-dependent scattering on the skin6
Subcellular analysis of nuclear and cytoplasmic redox indices differentiates breast cancer cell subtypes better than nuclear-to-cytoplasmic area ratio6
Accuracy and precision of depth-resolved estimation of attenuation coefficients in optical coherence tomography6
Increased fluorescence observation intensity during the photodynamic diagnosis of deeply located tumors by fluorescence photoswitching of protoporphyrin IX6
Improving diffuse optical tomography imaging quality using APU-Net: an attention-based physical U-Net model6
Bubble dynamics and speed of jets for needle-free injections produced by thermocavitation6
Light-guided dynamic phantom to mimic microvasculature for biomedical applications: an exploration for pulse oximeter6
Multiwavelength tissue-mimicking phantoms with tunable vessel pulsation6
Large field-of-view short-wave infrared metalens for scanning fiber endoscopy6
Margin assessment during breast conserving surgery using diffuse reflectance spectroscopy6
Integration of cellular-resolution optical coherence tomography and Raman spectroscopy for discrimination of skin cancer cells with machine learning6
Multivariate analysis of breast tissue using optical parameters extracted from a combined time-resolved fluorescence and diffuse reflectance system for tumor margin detection6
Can diffuse reflectance spectroscopy identify shuntodynia in pediatric hydrocephalus patients?6
Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW6
JBO 2024 List of Reviewers6
Depth-dependent attenuation and backscattering characterization of optical coherence tomography by stationary iterative method6
Polarized hyperspectral microscopic imaging system for enhancing the visualization of collagen fibers and head and neck squamous cell carcinoma6
Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics 6
Three-dimensional C-scan-based generation adversarial network with synthetic input to improve optical coherence tomography angiography6
Robust lumen segmentation based on temporal residual U-Net using spatiotemporal features in intravascular optical coherence tomography images6
Integrating optical coherence tomography and bioluminescence with predictive modeling for quantitative assessment of methicillin-resistant S. aureus biofilms6
Tetherless miniaturized point detector device for monitoring cortical surface hemodynamics in mice6
Affordable miniaturized speckle contrast diffuse correlation tomography device for depth-sensitive mapping of cerebral blood flow in rodents6
Transport-of-intensity phase imaging using commercially available confocal microscope6
Macroscopic inelastic scattering imaging using a hyperspectral line-scanning system identifies invasive breast cancer in lumpectomy and mastectomy specimens6
Spectral analysis of multiple scattering factors of turbid media for glucose measurement using near-infrared spectroscopy6
Acoustic resolution photoacoustic Doppler flowmetry for assessment of patient rectal cancer blood perfusion6
Quantitative second harmonic generation microscopy for characterizing collagen remodeling in papillary thyroid carcinoma6
Self-calibrated pulse oximetry algorithm based on photon pathlength change and the application in human freedivers6
Fiftieth anniversary of fiber optic–based fluorometry of brain mitochondrial NADH redox state monitored in vivo6
Brillouin microscopy in cancer research: a review6
Multifocal acoustic radiation force-based reverberant optical coherence elastography for evaluation of ocular globe biomechanical properties6
ArthroNavi framework: stereo endoscope-guided instrument localization for arthroscopic minimally invasive surgeries6
Considerations for the use of targeted fluorescence contrast agents to detect circulating cancer cell populations with diffuse in vivo flow cytometry6
Development and clinical validation of a clinically translatable non-chip-on-tip transvaginal imaging system (GynoSight v2.0) for early detection of premalignant cervical lesions5
Light-based therapy of infected wounds: a review of dose considerations for photodynamic microbial inactivation and photobiomodulation5
Needle guidance with Doppler-tracked polarization-sensitive optical coherence tomography5
Nanosecond multipulse retinal damage thresholds of elongated irradiance profiles in explant measurements and simulations5
Preclinical evaluation of Raman spectroscopy for pedicular screw insertion surgical guidance in a porcine spine model5
Quantitative phase imaging techniques for measuring scattering properties of cells and tissues: a review–part II5
Assessment of the activity of secondary caries lesions with short-wavelength infrared, thermal, and optical coherence tomographic imaging5
Introducing the Special Issue on Label-Free Quantitative Phase Imaging Honoring Prof. Gabriel Popescu, a Pioneer in Biomedical Optics5
Detection and margin assessment of thyroid carcinoma with microscopic hyperspectral imaging using transformer networks5
Spatiotemporal image reconstruction to enable high-frame-rate dynamic photoacoustic tomography with rotating-gantry volumetric imagers5
Review of imaging test phantoms5
Complex conjugate removal in optical coherence tomography using phase aware generative adversarial network5
DNA-hybridization on gold nanospheres: a dual-fluorescence investigation of surface loading and strand length effects5
Detection of low-frequency oscillations in neonatal piglets with speckle contrast diffuse correlation tomography5
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