OOIR: Observatory of International Research

Papers

(The TQCC of Preparative Biochemistry & Biotechnology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Research on soft sensing method of photosynthetic bacteria fermentation process based on ant colony algorithm and least squares support vector machine	59
Direct and cost-effective method for histone isolation from cultured mammalian cells	22
Production of milk-coagulating protease by fungus Pleurotus djamor through solid state fermentation using wheat bran as the low-cost substrate	20
UV mutagenesis for lipase overproduction from Bacillus cereus ATA179, nutritional optimization, characterization and its usability in the detergent industry	18
Purification of O-antigen for polysaccharide vaccine development against Salmonella paratyphi	18
Antimicrobial peptides (AMPs) from microalgae as an alternative to conventional antibiotics in aquaculture	17
A novel strategy to construct multi-strain starter cultures: an insight to evolve from natural to directed fermentation	17
The effects of different extraction methods on the structure and antioxidant properties of Bletilla striata polysaccharide	17
GFP fusion promotes the soluble and active expression of a pea actin isoform (PEAc1) in Escherichia coli	17
Microbial fermentation technology for degradation of saponins from peony seed meal	16
Synergistic phytohormonal stimulation for enhanced carotenogenesis in Dunaliella salina	16
Engineered Saccharomyces cerevisiae harbors xylose isomerase and xylose transporter improves co-fermentation of xylose and glucose for ethanol production	15
Xylanase of Bacillus sp. NIORKP76 grown under solid state fermentation: production, purification, characterization and its saccharification potential	15
Biosynthesis and characterization of terpolymer P(3HB- co -3HV- co -4HB) produced by <	15
Industrial-grade α-amylase production, purification, and functional characterization via co-culturing of Aspergillus niger	14
Immobilization of Coprinus comatus with magnetic alginate hydrogel microsphere for improving the antioxidant activity of fermentation products	13
Optimization of exopolysaccharide production from the novel Enterococcus species, using statistical design of experiment	13
Valorization of low-grade Gracilaria verrucosa biomass via optimized acid hydrolysis: a sustainable route to high-value sugars for bioproduct development	13
New wheat straw fermentation feed: recombinant Schizosaccharomyces pombe efficient degradation of lignocellulose and increase feed protein	13
Purification and biochemical characterization of lactoperoxidase from Jersey bovine milk and kefir: inhibition and molecular modeling	13
A secretory system for extracellular production of spider neurotoxin huwentoxin-I in Escherichia coli	13
Choice of gDNA isolation method has a significant impact on average murine Telomere Length estimates	13
Impacts of conventional and industrial wastewaters-based media on biomass production, nutrient dynamics, and fatty acid profile in a thraustochytrid culture	12
Biological synthesis of Glycyrrhiza glabra -based silver nanoparticles and determination of their bioactivities	11
A Box-Behnken design-optimized preparative strategy for anti-hyperuricemic flavonoids from Humulus lupulus L.: from extraction to bioactivity evaluation	11

Preparation of esculin acetates through transesterification reaction catalyzed by Novozyme 435 ^® and their Purification followed by NMR characterization	11
High-level production of poly-γ-glutamic acid by a newly isolated Bacillus sp. YJY-8 and potential use in increasing the production of tomato	10
PEGylation versus glycosylation: effect on the thermodynamics and thermostability of crisantaspase	10
Optimization of solid-state fermentation parameters and post-harvest stabilization for the mass production of Trichoderma citrinoviride EGE-K-128 micropr	10
High purity of human secreted phospholipase A2 group IIE in Pichia pastoris using basal salts medium comparison with YPD medium	10
Enhancement in T1 lipase purification recovery using the novel construct pGEX4T1/His-T1	10
In situ recovery of taxadiene using solid adsorption in cultivations with Saccharomyces cerevisiae	10
Optimization and purification of laccase activity from Mammaliicoccus sciuri isolated from the soils of Similipal, Odisha, India: a kinetics study of crystal violet dye	10
Kinetics of dye decolorization using heterogeneous catalytic system with immobilized Achromobacter xylosoxidans DDB6	10
Detoxification of areca nut acid hydrolysate and production of xylitol by Candida tropicalis (MTCC 6192)	9
Production of reverse transcriptase from Moloney murine Leukemia virus in Escherichia coli expression system	9
Selenopolysaccharides: advances in synthesis, structural characterization and biological applications	9
Optimization of alkali, acid and organic solvent pretreatment on rice husk and its techno economic analysis for efficient sugar production	9
Microencapsulation of astaxanthin-rich lipid extract from L. vannamei cephalothorax in calcium alginate matrix	9
Electrospun PVA based scaffolds engineered with bimetallic Ag-ZnO nanoparticles fabricated using Chromolaena odorata for wound healing applications	9
A systematic study on the characteristics and applications of laccases produced by fungi: insights on their potential for biotechnologies	9
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture	9
Optimization of the production conditions of tri-GOS and lactosucrose from lactose and sucrose with recombinant β-galactosidase	9
Bidirectional fermentation of Monascus and Mulberry leaves enhances GABA and pigment contents: establishment of strategy, studies of bioactivity and mechanistic	9
Optimization of chitosan-PEG-geranium oil nanoparticles and in-vitro studies on pancreatic ductal adenocarcinoma	9
High-throughput clone screening and upstream process optimization for recombinant therapeutic peptide expression: biosimilar teriparatide (PTH-34): a case study	9
Extracellular collagenase isolated from Streptomyces antibioticus UFPEDA 3421: purification and biochemical characterization	9
Studies on a new antimicrobial peptide from Vibrio proteolyticus MT110	9
A comprehensive study of glucose and oxygen gradients in a scaled-down model of recombinant HuGM-CSF production in thermoinduced Escherichia coli fed-batch cultures	8
Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum	8
Aqueous two-phase extraction and characterization of thermotolerant alkaliphilic Cladophora hutchinsiae xylanase: biochemical properties and potential applications in fr	8
Extraction optimization of Phellinus baumii residue polysaccharides and investigation of their anti-aging effects via	8
Morphological and genomic change in lipase-producing Bacillus licheniformis NCU CS-5 induced by atmospheric room temperature plasma mutagenesis	8
Biosurfactant production by Pseudomonas aeruginosa WARP_W1: kinetics and structural elucidation of glycolipids	8
Optimization of medium composition of Lactobacillus plantarum Y44 using Plackett – Burman and Box–Behnken designs	8
Enhancing methane yield and shifting microbial communities in anaerobic reactors treating lipid-rich dairy wastewater through exogenous lipase addition	8
Peptidomic profiling of Kaempferia parviflora and Zingiber officinale and their antioxidant potentials	8
Electrochemical system for detection of fermentation-derived bioethanol via cyclic voltammetry using nickel oxide modified glassy carbon electrode	8
Development of an efficient extraction and enrichment method for total flavonoids compounds from Erigeron breviscapus using ultrasound-assisted extraction and macroporous resin adsorption	8
In vitro antioxidant activity evaluation of pine nut peptides ( Pinus koraiensis ) fermented by Bacillus subtilis LS-45	8
Methane bioconversion to methanol by Methylotuvimicrobium buryatense 5GB1C: mechanistic insights using molecular simulations	8
In-situ transesterification of single-cell oil for biodiesel production: a review	8
Multi-functional xylanase from Aspergillus sydowii : biosynthesis of nanoconjugates, optimization by Taguchi approach and biodeinking potential	8
Enhanced phytoremediation and biosorption of cationic methylene blue dye by Acidomyces acidophilus ATCC 26774	7
Development of a real-time PCR protocol for the detection of chicken DNA in meat products	7
Measurement of yield and quality of DNA in human buffy coat is extraction method dependent	7
One-pot green and sustainable process for the biotransformation of sophoricoside to genistein from Fructus Sophorae with magnetic cellulose spheres immobilized	7
Isolation and characterization of yogurt starter cultures from traditional yogurts and growth kinetics of selected cultures under lab-scale fermentation	7
A green approach to natural products mediated synthesis of nanomaterial using Astragalus pennatulus , characterization, biological effect, and quantifica	7
Enhanced production of yellow fever virus through tailored culture media optimization	7
Experimental validation off-line a nonlinear controller for removal of chromium using non-living cells of Yarrowia lipolytica	7
Multi-omics analyses reveal the regulation mechanisms of organic acid biosynthesis in newly isolated lactic acid bacteria with application in corn biomass fermentation	7
Production of highly soluble native human paraoxonase 2 with potential anti-biofilm property	7
Efficient whole-cell biosynthesis of S-adenosyl-L-methionine by the engineered Escherichia coli with high ATP regenerating system	7
Expression of Vitreoscilla hemoglobin gene in different organisms: a new approach to increase the efficiency of various biological processes	7

Optimization of lyoprotectant for recombinant human acidic fibroblast growth factor by response surface methodology	7
Chitinase induction in Trichoderma harzianum : a solid-state fermentation approach using shrimp waste and wheat bran/commercial chitin for chitooligosaccharides synthesi	6
CgMRP1 improves ethanol fermentation performance of Candida glycerinogenes in undetoxified lignocellulosic hydrolysate	6
Cellulase production by Aspergillus fumigatus A4112 and the potential use of the enzyme in cooperation with surfactant to enhance floating oil recovery and methane produ	6
Preparation of magnetic polyacrylamide hydrogel with chitosan for immobilization of glutamate decarboxylase to produce γ-aminobutyric acid	6
Biosynthesis of zinc oxide nanoparticles using Tamarix chinensis extract: evaluation of antioxidant, antimicrobial, and anti-MCF-7 cancer activities	6
Enzyme inhibitory and bioactive potential of ultrasound-assisted water extract from Sideritis montana subsp. montana	6
Synergistic bioactivity and application of polysaccharide-based prebiotics and probiotics on animal feed, foods and medicines: a review	6
Immobilization, optimization, characterization and kinetic properties of polyphenol oxidase to multi-walled carbon nanotube	6
Promising approaches in the extraction, characterization, and biotechnological applications of ursolic acid: a review	6
Synthesis of new bio-activated carbon filled epoxy composites	6
Production of tannase from a newly isolated yeast, Geotrichum cucujoidarum using agro-residues	6
Adsorption and immobilization of β-glucosidase from Thermoascus aurantiacus on macroporous cryogel by hydrophobic interaction	6
The scarlet metabolite: recent insights into prodigiosin biosynthesis, biological activities and potential applications – a review	6
Microbased biorefinery for gold nanoparticle production: recent advancements, applications and future aspects	6
Bioconversion of mustard oil cake for production of lipase, optimization and direct immobilization from solid-state fermentation extract	6
Isolation, optimization, and bioactivity evaluation of Streptomyces qinglanensis VITABS23 from mangrove sediments: an in vitro and in silico study	6
Agro-industrial wastes revalorization as feedstock: production of lignin-modifying enzymes extracts by solid-state fermentation using white rot fungi	6
Enhancement of bacterial cellulose production by ethanol and lactic acid by using Gluconacetobacter kombuchae	6
Green synthesized silver nanoparticles and elicitors enhance stevioside glycoside production in the endophyte Acremonium sclerotigenum from	6
Evaluation of the effect of different organic solvents in the efficiency of the recovery of pullulan synthesized by Aureobasidium pullulans	5
Synergistic utilization of glucose and xylose for the myo-inositol biosynthesis in recombinant Escherichia coli BL21	5
Immobilization of Aspergillus terreus URM4658 inulinase in calcium alginate beads, evaluation of their biochemical characteristics and kinetic/thermodynamic parameters,	5
Optimizing the extraction of active components from Salvia miltiorrhiza by combination of machine learning models and intelligent optimization algorithms and its correla	5
Cost-effective, high-yield production of Pyrobaculum calidifontis DNA polymerase for PCR application	5
Optimization of asymmetric bioreduction conditions of 1-(thiophen-2-yl)ethanone by Weissella cibaria N9 using a desirability function-embedded face-centered optimization	5
Optimization and purification of a novel bacteriocin-like substance from Tarhana-originated Enterococcus faecium	5
Enhancing the production of L-proline in recombinant Escherichia coli BL21 by metabolic engineering	5
Glassy carbon electrode modified with rice husk biochar for sodium diclofenac determination using square-wave voltammetry	5
Zinc oxide nanoparticle mediated modulation of antimicrobial and physico-chemical properties of essential oil containing PVA nanocomposites	5
Production of a genetically encoded biosensor for evaluating enterovirus 71 3C protease inhibitors	5
A new hydrophobin candidate from Cladosporium macrocarpum with super-hydrophobic surface	5
Evaluation of different nutrient limitation strategies for the efficient production of poly(hydroxybutyrate‐co‐hydroxyvalerate) from waste frying oil and propionic acid in high cell density fermentati	5
Optimization of ultrasound- and enzymatic-assisted extractions of polyphenols from dried red onion peels and evaluation of their antioxidant activities	5
Optimization and extraction kinetic modeling of antioxidants, polyphenols, and flavonoids from Garcinia cambogia and Myristica fra	5
Characterization of a novel marine microbial uricase from Priestia flexa and evaluation of the effects of CMCS conjugation on its enzymatic properties	5
Statistical optimization of process variables for agarase production using Microbacterium sp. SS5 strain from non-marine sources	5
High-productive recovery and purification of superoxide dismutase from Tetraselmis chuii using integrated ultrasonication–aqueous two-phase system	5
Bioactive metabolites from edible fungi: evaluation of antioxidant potential and cytotoxicity on human cell lines	5
Optimizing the extraction of high-potency antioxidants from Solanum lycopersicum L. fruit: a comparative study of microwave-assisted, ultrasound-assisted	5
Removal of orange G dye by Aspergillus niger and its effect on organic acid production	5
Role of key enzymes in the production of docosahexaenoic acid (DHA) by Thraustochytrium sp. T01	5
Production of Rhizopus oryzae by solid state fermentation and evaluation of its biocomposite characteristics	5
Antibacterial and antibiofilm activity of extracts from sponge-associated bacterial endophytes	5
Rapid alcoholic fermentation of Candida glycerinogenes under aerobic conditions	5
Bio-fabrication of polymeric silver nanoparticles (Ag-NPs) using polysaccharide extracted from Ulva reticulata : structural and functional characterizati	5
Antioxidant and immunomodulatory activities of Rehmannia glutinosa extracts obtained with complex enzymes and ultrasonic wave	5
Deep eutectic solvent assisted recovery of high molecular weight levan from an isolated Neobacillus pocheonensis BPSCM4	5
Development of a novel method for recovery of intracellular biopolymer polyhydroxyalkanoate from Bacillus flexus by regulating a lambda phage lytic syste	5
Exploring the antioxidant potential of fermented turmeric pulp: effect of extraction methods and microencapsulation	5
Molecular dynamics simulation and validation of spiramycin extraction using the thermosensitive polymer NPE-108/water aqueous two-phase system	5
Harnessing algal biomass for sustainable energy: cultivation, strain improvement, and biofuel production	5