Nature Medicine

Article	Citations
AI to expand the reach of oncology trials	3415
CAR T cells drive multiple myeloma out	3303
Immunity boost against pancreatic cancer	1761
Treatment boost for spinal muscular atrophy	1317
Tocilizumab for the treatment of severe COVID-19	1118
Oligonucleotides get triglycerides under control	973
Gene therapy helps children with immunodeficiency	906
An implant to treat cluster headaches	840
A solid start for gene therapy in Tay–Sachs disease	810
A genetic test to predict adverse drug reactions	736
Digital intervention improves tuberculosis treatment outcomes	687
Health nationalism in Aotearoa New Zealand during COVID-19: problems for global health equity	633
Combination treatment for immune-mediated HIV remission	595
MRI decoders translate thoughts into words	572
Telehealth enables safe medication abortion in shifting health and legal contexts	570
Precision medicine for advanced breast cancer	553
Making treatment decisions in a void of information	552
siRNA against anti-thrombin reduces bleeding in hemophilia	527
International transmission complicates HCV elimination	524
Questionable role of new techniques in IVF embryo culture	509
Genomic reanalysis of a pan-European rare-disease resource yields new diagnoses	501
Population-based, first-tier genomic newborn screening in the maternity ward	500
Genetic basis of early onset and progression of type 2 diabetes in South Asians	494
Phenome-wide associations of sleep characteristics in the Human Phenotype Project	490
Estimating future heat-related and cold-related mortality under climate change, demographic and adaptation scenarios in 854 European cities	483

Diabetes risk after COVID-19	475
Sustainable, low-cost cancer diagnostics	473
Epidural stimulation of the cervical spinal cord for post-stroke upper-limb paresis	469
Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial	464
Big tech companies invest billions in health research	461
CAR T cells reach clinical milestone in prostate cancer	455
Deep-learning-enabled protein–protein interaction analysis for prediction of SARS-CoV-2 infectivity and variant evolution	454
Cancer immunotherapy: the quest for better biomarkers	451
Diagnostic classification of childhood cancer using multiscale transcriptomics	451
Wearables and AI better predict the progression of muscular dystrophy	424
Sexual and reproductive health and rights must be enshrined in universal healthcare	420
In vivo gene editing for inherited vision loss	405
Reporting standards for the use of large language model-linked chatbots for health advice	403
Heterogeneity and predictors of the effects of AI assistance on radiologists	398
Deep brain stimulation for obsessive–compulsive disorder: a crisis of access	394
RET inhibitors go tumor-agnostic	393
Unmasking the elusive erythropoietin-producing ‘Norn’ cell	391
CAR-T cell therapies for large B cell lymphoma	383
Repurposing a diabetes drug to treat Parkinson’s disease	383
Psychiatry goes psychedelic	381
Cracking the code of the Y chromosome	357
Vaccine development needs a boost	357
LLMs get a medical education	355
Immunotherapy for esophageal cancer	348
Recapitulating sensory feedback in artificial skin	347
The international Unity study for antivirals against mpox is a blueprint for future epidemics	343
Deciphering the genetic architecture of pain intensity	343
“I had to be with bodyguards with guns”—attacks on scientists during the pandemic	337
FDA approves first drug to delay type 1 diabetes	336
Subcutaneous infusion of exenatide and cardiovascular outcomes in type 2 diabetes: a non-inferiority randomized controlled trial	332
Hitting the right notes for pain relief	325
Easing the pain of endometriosis	324
Can an implanted minipump deliver for diabetes patients?	323
Career equity in medicine	318
Mapping peripartum brain changes in women	317
Predicting breast cancer risk in women of African ancestry	316
A plethora of gene therapies for hemoglobinopathies	308
Innovative approaches from recent conflicts can aid the health crisis in Ukraine	306
SCOTUS v. reproductive health in United States	306
A randomized controlled trial to test financial incentives for COVID-19 vaccination in Ghana	306
Renewed action on hypertension to improve health and reduce global inequalities	301
Lingering cardiac involvement in previously well people after mild COVID-19	297
The capacity of brain circuits to enhance psychiatry	294
What will it take to make precision health a global reality	289
Navigating the health frontiers of Africa’s climate challenge	286
Precision public health in the era of genomics and big data	285
Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron	283
JAK inhibitor reinvigorates cancer immunotherapy	281
A life-course multisectoral approach to precision health in LMICs	280
Improving the FITness of colorectal cancer screening	277

A little knowledge can be a dangerous thing	277
Supported decision-making can advance clinical research participation for people with disabilities	277
Tackling under-reporting of violence against women	276
A fluid biomarker accurately detects tau aggregate pathology in Alzheimer’s disease	269
Rare and common genetic determinants of metabolic individuality and their effects on human health	264
Longitudinal analysis shows how microbiome changes might influence responses to immune checkpoint blockade	262
The poorest and most vulnerable communities should be the first to be vaccinated	262
Base editors in the clinic	260
A blood test for prenatal genetic diagnosis	258
Telemedicine for abortion access	254
Epigenomic dysregulation correlates with arachnoid cyst formation and neurodevelopmental symptoms	253
Telemonitoring for complicated pregnancies	251
Persistent mutations render cancer cells susceptible to immunotherapy	251
Putting the brakes on Alzheimer’s disease	249
Progress at last against RSV	247
AI as a new paradigm for risk-based screening for breast cancer	247
Reply to: Concerns about the Burden of Proof studies	246
Liquid biopsies and tumor mutational burden: the cutoff conundrum	244
Trialing precision medicine for type 2 diabetes	244
Microbiome research in Africa must be based on equitable partnerships	241
Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial	241
Licensed H5N1 vaccines generate cross-neutralizing antibodies against highly pathogenic H5N1 clade 2.3.4.4b influenza virus	240
Integrated image-based deep learning and language models for primary diabetes care	239
Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition	238
Hippocampal network activity forecasts epileptic seizures	237
Brain aging patterns in a large and diverse cohort of 49,482 individuals	236
Antisense oligonucleotide therapy in an individual with KIF1A-associated neurological disorder	230
Health benefits of fermented foods	230
The recombinant shingles vaccine is associated with lower risk of dementia	230
Broad-capture proteomics and machine learning for early detection of type 2 diabetes risk	229
A common framework for health data governance standards	228
New and emerging approaches to treat psychiatric disorders	228
Hindsight is 2020? Lessons in global health governance one year into the pandemic	223
Concerns about the Burden of Proof studies	222
HIPAA is a misunderstood and inadequate tool for protecting medical data	219
Evidence-based COVID-19 policy-making in schools	218
Aiming for equitable precision medicine in diabetes	217
Long-term health risks linked to childbirth	216
A global initiative to deliver precision health in diabetes	215
Monitoring metabolic changes during the menstrual cycle	214
Five award-winning researchers share their tips for inclusive health research	214
Rise in ambient temperature is associated with increased mortality in Latin America	212
Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation	209
Inhaled particulate accumulation with age impairs immune function and architecture in human lung lymph nodes	208
Gene editing advances on all fronts	208
Genetic testing in the neonatal ICU	207
How publishers can fight misinformation in and about science and medicine	206
Phthalate exposure linked to adverse pregnancy outcomes	204
Prescription for a healthy diet	204
Promoting gender equity in the scientific and health workforce is essential to improve women’s health	203
Dementia research needs a global approach	202
How virtual reality therapy is shaping mental health	200
Nirmatrelvir/ritonavir use in pregnant women with SARS-CoV-2 Omicron infection: a target trial emulation	200
The uncertain science of preimplantation and prenatal genetic testing	200
Delivering high-quality childbirth care	195
Dynamics and durability of HIV-1 neutralization are determined by viral replication	193
The role of research in China’s successful elimination of malaria	190
Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved	190
Effectiveness and safety of telehealth medication abortion in the USA	188
Evidence for iatrogenic transmission of Alzheimer’s disease	188
Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist	186
Screening for fibrosis to diagnose liver diseases early: the LIVERSCREEN project	186
HIV prevention through PrEP in cisgender women	184
Clinical trials assess a precision-medicine approach to cancer screening	184
Semaglutide and risk of suicidal ideations	182
A foundation model for clinician-centered drug repurposing	181
Datopotamab–deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial	181
Spatial multiomic landscape of the human placenta at molecular resolution	180
Computational brain models map diversity embedded in aging and dementia	179
HIV-1 remission following stem cell transplant without CCR5Δ32 mutation	179
Digital AVATAR therapy for distressing voices in psychosis: the phase 2/3 AVATAR2 trial	179
Fratricide-resistant CD7-CAR T cells in T-ALL	179
An explainable foundation model for drug repurposing	179
The battle for COVID-19 vaccines highlights the need for a new global governance mechanism	177
Citizen science as an instrument for women’s health research	177
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases	176
Integrative microbiomics in bronchiectasis exacerbations	175
Vaccine development for emerging infectious diseases	174
Prisons as ecological drivers of fitness-compensated multidrug-resistant Mycobacterium tuberculosis	173
One Health interprofessional stewardship to combat antimicrobial resistance	173

APOE4 homozygosity is a new genetic form of Alzheimer’s disease	171
Putting the MD back into MDMA	170
Molecular pathology markers of FTD and ALS in blood extracellular vesicles	169
An AI chatbot for talking therapy referrals	169
Tissue perfusion pressure enables continuous hemodynamic evaluation and risk prediction in the intensive care unit	169
Long COVID includes breathing and reproductive problems and has a range of risk factors	168
COVID-19 vaccines: acting on the evidence	166
HIV drug resistance to integrase inhibitors in low- and middle-income countries	165
Phenotypic signatures in clinical data enable systematic identification of patients for genetic testing	165
The future of personalized brain stimulation	164