Nature Medicine

Papers
(The H4-Index of Nature Medicine is 173. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
SCOTUS v. reproductive health in United States3423
Rise in ambient temperature is associated with increased mortality in Latin America1438
Telemonitoring for complicated pregnancies1436
How virtual reality therapy is shaping mental health1396
LLMs get a medical education944
Questionable role of new techniques in IVF embryo culture780
A genetic test to predict adverse drug reactions775
Easing the pain of endometriosis738
Liquid biopsies and tumor mutational burden: the cutoff conundrum697
A global metric of immune health650
Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology626
Solving medicine’s data bottleneck: Nightingale Open Science600
In vivo gene editing for inherited vision loss597
Recapitulating sensory feedback in artificial skin597
A fluid biomarker accurately detects tau aggregate pathology in Alzheimer’s disease574
Concerns about the Burden of Proof studies557
First tumor-agnostic approval for an ADC553
Remotely delivered weight management for people with long COVID and overweight: the randomized wait-list-controlled ReDIRECT trial547
Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids542
Not all KRAS-mutated pancreatic cancers are equal — mutant dosage matters516
Longitudinal analysis shows how microbiome changes might influence responses to immune checkpoint blockade512
Author Correction: Financial incentives for COVID-19 vaccines in a rural low-resource setting: a cluster-randomized trial508
Author Correction: Dapagliflozin in heart failure with improved ejection fraction: a prespecified analysis of the DELIVER trial487
Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes483
An AI chatbot for talking therapy referrals473
Can an implanted minipump deliver for diabetes patients?450
The capacity of brain circuits to enhance psychiatry429
Author Correction: Digital consults in heart failure care: a randomized controlled trial417
AI as a new paradigm for risk-based screening for breast cancer416
HIV prevention through PrEP in cisgender women416
Author Correction: Pembrolizumab and cabozantinib in recurrent metastatic head and neck squamous cell carcinoma: a phase 2 trial411
The role of research in China’s successful elimination of malaria411
Estimating the total effect of anthropogenic climate change on human health and wellbeing409
Promoting gender equity in the scientific and health workforce is essential to improve women’s health408
Pregnant and lactating women should be included in clinical trials for cardiovascular disease404
Combating vaccine revisionism402
Gene-edited pig liver successfully transplanted into human396
HIPAA is a misunderstood and inadequate tool for protecting medical data389
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial380
FDA approves first drug to delay type 1 diabetes375
The WHO genomics program of work for equitable implementation of human genomics for global health373
Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma370
Hippocampal network activity forecasts epileptic seizures370
An explainable foundation model for drug repurposing368
The uncertain science of preimplantation and prenatal genetic testing364
Targeted therapy for osteoarthritis: progress and pitfalls359
Urgent action is needed to confront artemisinin partial resistance in African malaria parasites356
Continuous glucose monitoring and intrapersonal variability in fasting glucose356
The inconvenient reality of AI-assisted embryo selection in IVF356
Estimating future heat-related and cold-related mortality under climate change, demographic and adaptation scenarios in 854 European cities353
Licensed H5N1 vaccines generate cross-neutralizing antibodies against highly pathogenic H5N1 clade 2.3.4.4b influenza virus350
In utero origin of myelofibrosis presenting in adult monozygotic twins346
Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19345
CanScreen5, a global repository for breast, cervical and colorectal cancer screening programs336
A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease335
Supported decision-making can advance clinical research participation for people with disabilities333
Trastuzumab deruxtecan in HER2-positive breast cancer with brain metastases: a single-arm, phase 2 trial331
Author Correction: Unexplained post-acute infection syndromes330
Pembrolizumab for advanced urothelial carcinoma: exploratory ctDNA biomarker analyses of the KEYNOTE-361 phase 3 trial325
Integrated image-based deep learning and language models for primary diabetes care320
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy318
Allogeneic CD5-specific CAR-T therapy for relapsed/refractory T-ALL: a phase 1 trial316
Changing climate and socioeconomic factors contribute to global antimicrobial resistance316
Anemia in women — an intractable problem that requires innovative solutions312
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial310
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants305
Phenotypic signatures in clinical data enable systematic identification of patients for genetic testing304
Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial303
The landscape of mRNA nanomedicine299
Partitioned polygenic risk scores identify distinct types of metabolic dysfunction-associated steatotic liver disease298
Will ChatGPT transform healthcare?296
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses292
Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial291
Integrating the environmental and genetic architectures of aging and mortality288
Low-voltage-area ablation for persistent atrial fibrillation: a randomized controlled trial284
IL-6 inhibition with clazakizumab in patients receiving maintenance dialysis: a randomized phase 2b trial282
Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality282
WHO sets research agenda for refugee and migrant health281
Machine learning improves prediction of clinical outcomes for invasive breast cancers280
The Yearbook280
An anti-obesity drug from the diabetes toolbox276
An outdated loophole is letting faulty lab tests hit the market275
Handwriting with a brain implant270
Rethinking aspirin for heart health269
High COVID-19 death toll in Africa269
Health in the Amazon268
Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts267
The visible and hidden mortality caused by flooding264
Using unlabeled data to enhance fairness of medical AI263
Mapping the cellular landscape of the brain261
Acquired blood mutations cause acute kidney injury via dysregulated inflammation260
Author Correction: Identification of a new orthonairovirus associated with human febrile illness in China259
Familial confounding in the associations between maternal health and autism257
Microbiome–metabolome dynamics associated with impaired glucose control and responses to lifestyle changes256
Technology-assisted cognitive-behavioral therapy for perinatal depression delivered by lived-experience peers: a cluster-randomized noninferiority trial255
Simulation-based estimates and projections of global, regional and country-level maternal mortality by cause, 1990–2050253
Steps to prevent and respond to an H5N1 epidemic in the USA252
A benchmarking crisis in biomedical machine learning251
Maternal diabetes and risk of attention-deficit/hyperactivity disorder in offspring in a multinational cohort of 3.6 million mother–child pairs249
Anti-amyloid could help prevent genetic form of Alzheimer’s disease246
A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial245
Mutations in the U4 snRNA gene RNU4-2 cause one of the most prevalent monogenic neurodevelopmental disorders244
Multi-omic profiling a defined bacterial consortium for treatment of recurrent Clostridioides difficile infection242
Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial240
Evaluation of the extended efficacy of the Dengvaxia vaccine against symptomatic and subclinical dengue infection240
Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial239
Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primates239
Open Letter to G7 and G20 leaders: resolve global crises to secure our future237
From neoadjuvant to organ-sparing immunotherapy for colorectal cancer237
Reply to Guyton, J. R. & Boden, W. E.; Schreiber, S. et al.237
Use of mobile diagnostics and digital clinical trials in cardiology236
An African One Health network for antimicrobial resistance and neglected tropical diseases234
Coproducing health research with Indigenous peoples234
The expanding universe of checkpoint inhibitors for nasopharyngeal cancer233
Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV230
A gene-by-sex interaction contributes to liver disease susceptibility in women229
Health benefits of calorie restriction227
Prenatal exposure to famine affects lifelong health225
How patient advocates influence health policy224
Meningioma risk stratification with a targeted gene-expression biomarker223
siRNA therapy lowers triglycerides in patients with rare condition223
Brain pathology of COVID-19220
The effect of embryonic genome imbalances on pregnancy220
Using genetics to predict toxicity of cancer immunotherapy216
Menstrual health without stigma215
Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination214
Smartwatch- and smartphone-based remote assessment of brain health and detection of mild cognitive impairment214
Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults212
Partial recovery of visual function in a blind patient after optogenetic therapy211
Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial209
Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis207
The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans205
Mpox continues to spread in Africa and threatens global health security203
Artificial intelligence–enabled electrocardiograms for identification of patients with low ejection fraction: a pragmatic, randomized clinical trial201
Salt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial201
Genome-wide polygenic score to predict chronic kidney disease across ancestries200
Advancing global antibiotic research, development and access200
The limits of fair medical imaging AI in real-world generalization199
Emerging diagnostics and therapeutics for Alzheimer disease198
Prospective implementation of AI-assisted screen reading to improve early detection of breast cancer196
Clinical AI tools must convey predictive uncertainty for each individual patient194
D3S-001 in advanced solid tumors with KRASG12C mutations: a phase 1 trial194
Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety192
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial190
AI-generated text may have a role in evidence-based medicine189
Author Correction: Autologous T cell therapy for PRAME+ advanced solid tumors in HLA-A*02+ patients: a phase 1 trial188
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer186
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations186
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity186
Determinants of COVID-19 vaccination status and hesitancy among older adults in China186
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial186
A meta-analysis of GFR slope as a surrogate endpoint for kidney failure185
Self-improving generative foundation model for synthetic medical image generation and clinical applications185
Author Correction: Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury185
Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials184
An integrated cell atlas of the lung in health and disease183
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia183
Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy183
Could video games be good for your health?181
Pig-to-human transplants inch closer to reality181
Gene therapy for alcohol-use disorder181
ALS therapy hits molecular mark but misses clinical one181
A human brain circuit for addiction remission179
Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year179
A pinch of salt for heart disease179
A smart solution for detecting ear problems179
AI-guided precision parenteral nutrition for neonatal intensive care units178
Challenges with benchmarking of MDMA-assisted psychotherapy177
Reduction in life expectancy in Brazil after COVID-19175
Author Correction: The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial175
Cities, communities and clinics can be testbeds for human exposome and aging research174
Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial174
The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology173
The economic value of reducing avoidable mortality173
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