OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Peptide Science is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
New generation of cell‐penetrating peptides: Functionality and potential clinical application	41
Antimicrobial therapeutic enhancement of levofloxacin via conjugation to a cell‐penetrating peptide: An efficient sonochemical catalytic process	37
Chemical modifications of tryptophan residues in peptides and proteins	32
New trends in the development of multifunctional peptides to functionalize biomaterials	22
The effect of structural modification of antimicrobial peptides on their antimicrobial activity, hemolytic activity, and plasma stability	22
Peptide‐based hydrogels as delivery systems for doxorubicin	20
Naturally occurring and synthetic peptides: Efficient tyrosinase inhibitors	19
Multiple action mechanism and in vivo antimicrobial efficacy of antimicrobial peptide Jelleine‐I	19
N‐terminal acetylation of antimicrobial peptide L163 improves its stability against protease degradation	17
Peptide hydrogels for affinity‐controlled release of therapeutic cargo: Current and potential strategies	16
Heterochiral tetrapeptide self‐assembly into hydrogel biomaterials for hydrolase mimicry	14
Antioxidant activities of major tryptophyllin L peptides: A joint investigation of Gaussian‐based 3D‐QSAR and radical scavenging experiments	13
Peptide‐based covalent inhibitors of protein–protein interactions	13
Antimicrobial activity and secondary structure of a novel peptide derived from ovalbumin	12
Design of acid‐activated cell‐penetrating peptides with nuclear localization capacity for anticancer drug delivery	12
Effects of N‐terminal modifications on the stability of antimicrobial peptide SAMP‐A4 analogues against protease degradation	11
Cationic amphipathic peptide analogs of cathelicidin LL‐37 as a probe in the development of antimicrobial/anticancer agents	10
Capacity for increased surface area in the hydrophobic core of β‐sheet peptide bilayer nanoribbons	10
Similarities and differences for membranotropic action of three unnatural antimicrobial peptides	10
Exploring the copper binding ability of Mets7 hCtr‐1 protein domain and His7 derivative: An insight in Michael addition catalysis	9
Identification of β‐aminopyrrolidine containing peptides as β‐amyloid aggregation inhibitors for Alzheimer's disease	9
Self‐assembling systems comprising intrinsically disordered protein polymers like elastin‐like recombinamers	8
Interactions of two enantiomers of a designer antimicrobial peptide with structural components of the bacterial cell envelope	8
DIC/Oxyma‐based accelerated synthesis and oxidative folding studies of centipede toxin RhTx	8
Amphiphilic conjugates of ferrocene with amino acids and peptides: Design, synthesis, and studies on their aggregation behavior	7

Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion	7
Effect of positive charges in the structural interaction of crabrolin isoforms with lipopolysaccharide	7
Inhibitory and anti‐inflammatory effects of two antimicrobial peptides moronecidin and temporin‐1Dra against Propionibacterium acnes in vitro and in vivo	7
Targeted β‐catenin ubiquitination and degradation by multifunctional stapled peptides	7
Net charge tuning modulates the antiplasmodial and anticancer properties of peptides derived from scorpion venom	7
Discovery, synthesis, and optimization of teixobactin, a novel antibiotic without detectable bacterial resistance	7
Sequence sensitivity and pH dependence of maleimide conjugated N‐terminal cysteine peptides to thiazine rearrangement	7
Cyclic dipeptide‐based small molecules modulate zinc‐mediated liquid–liquid phase separation of tau	7
Esc‐1GN shows therapeutic potentials for acne vulgaris and inflammatory pain	6
Structure–activity relationship study of amphipathic antimicrobial peptides using helix‐destabilizing sarcosine	6
Self‐assembling tripeptide forming water‐bound channels and hydrogels	6
Nucleation and growth inhibition of biological minerals by cementum attachment protein‐derived peptide (CAP‐pi)	6
Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes	5
Current synthetic chemistry towards cyclic antimicrobial peptides	5
Design, synthesis, and evaluation of peptide‐imidazo[1,2‐a]pyrazine bioconjugates as potential bivalent inhibitors of the VirB11 ATPase HP0525	5
Human estrogen sulfotransferase and its related fluorescently labeled decapeptides specifically interact with oxidized low‐density lipoprotein	5
Expression and purification of the native C‐amidated antimicrobial peptide maculatin 1.1	5
d‐Amino acid substitutions and dimerization increase the biological activity and stability of an IL‐15 antagonist peptide	5
Antimicrobial, cytotoxic, and insulin‐releasing activities of the amphibian host‐defense peptide ocellatin‐3N and its L‐lysine‐substituted analogs	5
Efficient synthesis of Aib⁸‐Arg³⁴‐GLP‐1 (7–37) by liquid‐phase fragment condensation	4
Different directions for retro‐inverso peptides	4
Comparison of different protein precipitation and solid‐phase extraction protocols for the study of the catabolism of peptide drugs by LC‐HRMS	4
Solid‐phase synthesis and bioactivity evaluation of cherimolacyclopeptide E	4
Cyclic peptides bearing the d‐Phe‐2‐Abz turn motif: Structural characterization and antimicrobial potential	4
The ring size of monocyclic ET‐1 controls selectivity and signaling efficiency at both endothelin receptor subtypes	4
Structural and functional swapping of amyloidogenic and antimicrobial peptides: Redefining the role of amyloidogenic propensity in disease and host defense	4
S‐Benzyl cysteine based cyclic dipeptide super hydrogelator: Enhancing efficacy of an anticancer drug via sustainable release	4
Development of membrane‐active peptide therapeutics in oncology	4
Position‐coded multivalent peptide–peptide interactions revealed by tryptophan‐scanning mutagenesis	4
Transcytosis mechanisms of cell‐penetrating peptides: Cation‐independent CC12 and cationic penetratin	4
SARS‐CoV‐2 main protease inhibitors: What is moving in the field of peptides and peptidomimetics?	4
Revisiting bone morphogenetic protein‐2 knuckle epitope and redesigning the epitope‐derived peptides	4
The synthesis and activity evaluation of N‐acylated analogs of echinocandin B with improved solubility and lower toxicity	3
Self‐assembly of a peptide sequence, EKKE, composed of exclusively charged amino acids: Role of charge in morphology and lead binding	3
Anti‐colon cancer activity tracking isolation of peptide from ginseng leaves and potential mechanisms evaluation in vitro and in vivo	3
Labeling and receptor affinity of an ultra‐short somatostatin analogue Thz‐Phe‐D‐Trp‐Lys‐Thr‐DOTA	3
Ameliorative effect of dandelion (Taraxacum officinale) peptides on benzo(a)pyrene‐induced oxidative stress and inflammation in human umbilical vein endothelial cells	3
Hyperglucosylated adhesin‐derived peptides as antigenic probes in multiple sclerosis: Structure optimization and immunological evaluation	3
Antifungal activity and mode of action of synthetic peptides derived from the tick OsDef2 defensin	3
Modulation of hydrogel networks by metal ions	3
Design, synthesis, and evaluation of the self‐assembled antimicrobial peptides based on the ovalbumin‐derived peptide TK913	3
Stapled peptides as potential inhibitors of SARS‐CoV‐2 binding to the hACE2 receptor	3
Application of 2,2′‐dipyridyl disulfide‐mediated thiazolidine ring‐opening reaction to glycoprotein synthesis: Total chemical synthesis of evasin‐3	3
Effect of the powerful plasticity of the tert‐butyl side chain on the conformational equilibrium of ascidiacyclamides	3
Total synthesis of the natural, medium‐length, peptaibol pentadecaibin and study of the chemical features responsible for its membrane activity	3
Mutual structural effects of unmodified and pyroglutamylated amyloid β peptides during aggregation	3
Designed novel nuclear localizing anticancer peptide targets p53 negative regulator MDM2 protein	3
Molecular characterization and immunohistochemical localization of tilapia piscidin 3 in response to Aeromonas hydrophila infection in Nile tilapia	3
Solution structure of the anticancer p28 peptide in biomimetic medium	3
Longer charged amino acids favor β‐strand formation in hairpin peptides	3

Synergistic effects of short peptides and antibiotics against bacterial and fungal strains	3
Composition‐dependent multivalency of peptide–peptide interactions revealed by tryptophan‐scanning mutagenesis	3
Hydrocarbon stapling modification of peptide alyteserin‐2a: Discovery of novel stapled peptide antitumor agents	3
Biophysical study of the structure and dynamics of the antimicrobial peptide maximin 1	3
Insight into the bovine milk peptide LPcin‐YK3 selection in the proteolytic system of Lactobacillus species	2
Secondary structures, dynamics, and DNA binding of the homeodomain of human SIX1	2
Reversible crosslinked assembly of a trimeric coiled‐coil peptide into a three‐dimensional matrix for cell encapsulation and release	2
Chemical approaches for the preparation of ubiquitinated proteins via natural linkages	2
Conjugates of adenosine mimetics and arginine‐rich peptides serve as inhibitors and fluorescent probes but not as long‐lifetime photoluminescent probes for protein arginine methyltransferases	2
Effects of long‐acting analogues of lamprey GLP‐1 and paddlefish glucagon on alpha‐ to beta‐cell transdifferentiation in an insulin‐deficient transgenic mouse model	2
Strategies for the highly efficient synthesis of erythropoietin N‐glycopeptide hydrazides	2
Tryptophan‐cardanol fluorescent nanoparticles inhibit α‐synuclein aggregation and disrupt amyloid fibrils	2
Automated solid‐phase synthesis of metabolically stabilized triazolo‐peptidomimetics	2
Why to target G‐quadruplexes using peptides: Next‐generation G4‐interacting ligands	2
Intracellular targets: A multiple cargo transporting molecule	2
Glucopeptides derived from myelin‐relevant proteins and hyperglucosylated nontypeable Haemophilus influenzae bacterial adhesin cross‐react with multiple sclerosis specific antibodies	2
Metal ion‐induced assembly of dipeptide‐attached perylenediimide for fluorometric “turn on” detection of biologically important small molecule	2
Opening the amino acid toolbox for peptide‐based NTS2‐selective ligands as promising lead compounds for pain management	2
The first non‐helical Aib‐containing hexapeptide: The crystal structure of Z‐Gly‐Aib‐Gly‐Aib‐Gly‐Aib‐OtBu	2
Discovery of a novel antifungal agent: All‐hydrocarbon stapling modification of peptide Aurein1.2	2
Assessment of ¹⁷⁷Lu‐labeled carboxyl‐terminated polyamidoamine (PAMAM) dendrimer‐RGD peptide conjugate	2
Designing the antimicrobial peptide with centrosymmetric and amphipathic characterizations for improving antimicrobial activity	2
Safety‐catch linkers for Fmoc solid‐phase synthesis of peptide thioesters and hydrazides by amide‐to‐imide activation	2
N^α‐Methylation of arginine: Implications for cell‐penetrating peptides	2
Virtual screening and rational design of antioxidant peptides based on tryptophyllin L structures isolated from the Litoria rubella frog	2
Activities of a broad‐spectrum antimicrobial peptide analogue SAMP‐A4‐C8 and its combat against pneumonia in Staphylococcus aureus‐infected mice	2
Synthesis and characterization of two potential impurities (des‐ethyl‐Ganirelix) generated in the Ganirelix manufacturing process	2
A robust preparation method for the amyloidogenic and intrinsically disordered amyloid‐α peptide	2
Nuclear magnetic resonance studies on conformation and stability of mastoparan in methanol	2