Immunity

Article	Citations
Immunology of COVID-19: Current State of the Science	1292
SARS-CoV-2 Vaccines: Status Report	917
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals	903
Herd Immunity: Understanding COVID-19	821
COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome	560
Inflammation in obesity, diabetes, and related disorders	495
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms	489
Cytokine Storms: Understanding COVID-19	488
Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses	428
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity	376
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination	349
Autophagy in inflammation, infection, and immunometabolism	333
Distinct Early Serological Signatures Track with SARS-CoV-2 Survival	331
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway	321
Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation	307
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver	283
The CD47-SIRPα Immune Checkpoint	281
Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity	279
SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation	277
Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients	277
MDSC: Markers, development, states, and unaddressed complexity	276
Determinants of Resident Tissue Macrophage Identity and Function	276
Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease	269
Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein	269
The immunology of sepsis	267

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses	264
Lessons for COVID-19 Immunity from Other Coronavirus Infections	264
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19	263
Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19	261
A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice	260
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors	257
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging	255
Chemokines and the immune response to cancer	254
Low-Avidity CD4+ T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19	253
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis	244
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease	233
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection	229
Germinal Center and Extrafollicular B Cell Responses in Vaccination, Immunity, and Autoimmunity	226
Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease	226
The Neutrophil	224
Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer	217
Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19	213
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses	209
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations	209
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions	206
Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells	200
Respiratory Virus Infections: Understanding COVID-19	200
Microglia: Immune and non-immune functions	197
SARS-CoV-2 Epitopes Are Recognized by a Public and Diverse Repertoire of Human T Cell Receptors	184
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species	184
Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis	184
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity	183
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation	177
Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion	176
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity	175
PD-1-Expressing SARS-CoV-2-Specific CD8+ T Cells Are Not Exhausted, but Functional in Patients with COVID-19	174
COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses	172
Cytotoxic CD4+ T cells in cancer: Expanding the immune effector toolbox	170
Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity	167
Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity	166
Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies	164
Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling	161
Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke	159
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity	158
Accelerated COVID-19 vaccine development: milestones, lessons, and prospects	158
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children	156
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy	151
Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity	151
Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo	149
FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells	149
Fibroblast-macrophage reciprocal interactions in health, fibrosis, and cancer	147
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans	145
Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor	144
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses	141
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy	141

The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans	138
The Intersection of Epigenetics and Metabolism in Trained Immunity	138
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19	135
Biology of lung macrophages in health and disease	131
The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis	129
Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response	129
Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens	128
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade	126
Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity	125
Implications of Sex Differences in Immunity for SARS-CoV-2 Pathogenesis and Design of Therapeutic Interventions	122
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses	119
T Cell Memory: Understanding COVID-19	117
An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells	117
Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids	113
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2	113
Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid	113
CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis	113
Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants	112
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes	111
Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration	109
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity	108
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation	108
Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage	108
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake	107
The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts	107
The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling	107
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA	106
mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants	105
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity	105
Astrocyte-immune cell interactions in physiology and pathology	104
Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant	104
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development	102
B cell memory: understanding COVID-19	102
A subset of Kupffer cells regulates metabolism through the expression of CD36	100
The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24	100
Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine	99
A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages	98
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment	98
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets	98
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection	97
Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer	96
A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver	96
Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease	95
Germline genetic contribution to the immune landscape of cancer	93
Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA	91
Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge	91
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control	89
Metabolic adaptation of lymphocytes in immunity and disease	89
Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons	88
Transcriptional Networks Driving Dendritic Cell Differentiation and Function	88
MAIT Cell Development and Functions: the Microbial Connection	88
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors	87
Transition to endemicity: Understanding COVID-19	86
Modification of Proteins by Metabolites in Immunity	86
Innate immune mechanisms of mRNA vaccines	85
The unique biology of germinal center B cells	85
Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy	84
Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy	83
Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2	82
Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection	82
COVID-19 vaccine access in Africa: Global distribution, vaccine platforms, and challenges ahead	81
Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity	81
Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins	79
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity	79
Itch: A Paradigm of Neuroimmune Crosstalk	78
CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells	78
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery	78
Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation	77
Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses	77
Resident cardiac macrophages mediate adaptive myocardial remodeling	77
Liver macrophages in health and disease	77
The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation	77
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes	77
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells	77
Deconstructing Mechanisms of Diet-Microbiome-Immune Interactions	76
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor	76
mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern	76
SARS-CoV-2 infections in children: Understanding diverse outcomes	76
Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING	75
Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity	75

Systemic Immunometabolism: Challenges and Opportunities	74
MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function	74
Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia	73
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming	73
Antibody-mediated neutralization of SARS-CoV-2	73
Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties	73
Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity	73
Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells	72
Antigenic drift: Understanding COVID-19	72
Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation	71
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs	71
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases	71
Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis	71
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis	70
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas	69
Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease	69
Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow	69
Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection	69
Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis	69
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections	69
Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells	68
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses	68
A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope	67
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation	67
Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function	67
Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β	67
Redefining macrophage and neutrophil biology in the metastatic cascade	67
Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche	66
Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response	66
Mucosal immune responses to infection and vaccination in the respiratory tract	66
Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses	66
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage	65
Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques	65
SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic	65
Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides	65
Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring	64
The pathogenesis of rheumatoid arthritis	64
Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma	63
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching	63
TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures	63
Dietary Regulation of Immunity	63
A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function	63
COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge	63
Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut	62
Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1	62
Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment	62
Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism	61
Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages	61
A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation	60
Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses	60
Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron	60
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones	60
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway	60
Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3	59
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade	59
Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses	59
Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity	59
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes	58
The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries	58
Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development	57
Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy	57
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses	56
Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation	56
Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer	56
Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses	56
Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93	54
Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity	54
Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation	54
The COVID-19 Serology Studies Workshop: Recommendations and Challenges	54
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity	53
Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress	53
SARS-CoV-2 in immunocompromised individuals	52
T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes	52
Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function	52
Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges	52
Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation	51
Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles	51
Principles of regulatory T cell function	50
Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers	50
Emerging roles of innate and adaptive immunity in Alzheimer’s disease	50
Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants	50
Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma	50
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma	50