Shock

Article	Citations
Neutrophil-to-Lymphocyte Ratio and Outcomes in Louisiana COVID-19 Patients	84
Hemoglobin-based Oxygen Carriers: Current State-of-the-art and Novel Molecules	67
Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Attenuate LPS-Induced ARDS by Modulating Macrophage Polarization Through Inhibiting Glycolysis in Macrophages	64
Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Coronavirus	62
Mechanisms of Toxicity and Modulation of Hemoglobin-based Oxygen Carriers	58
Fibrinolysis Shutdown and Thrombosis in a COVID-19 ICU	57
Effects of Corticosteroid Treatment for Non-Severe COVID-19 Pneumonia: A Propensity Score-Based Analysis	51
Temporal Trends and Clinical Outcomes Associated with Vasopressor and Inotrope Use in The Cardiac Intensive Care Unit	49
Plasma miR-370-3P as a Biomarker of Sepsis-Associated Encephalopathy, the Transcriptomic Profiling Analysis of Microrna-Arrays From Mouse Brains	38
Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes	35
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS	35
Resuscitative Strategies to Modulate the Endotheliopathy of Trauma: From Cell to Patient	34
SARS-CoV-2/COVID-19: Evolving Reality, Global Response, Knowledge Gaps, and Opportunities	33
Preadmission Antihypertensive Drug Use and Sepsis Outcome: Impact of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin Receptor Blockers (ARBs)	28
Administration of Candida Albicans to Dextran Sulfate Solution Treated Mice Causes Intestinal Dysbiosis, Emergence and Dissemination of Intestinal Pseudomonas Aeruginosa and Lethal Sepsis	28
The Use of Tranexamic Acid (TXA) for the Management of Hemorrhage in Trauma Patients in the Prehospital Environment: Literature Review and Descriptive Analysis of Principal Themes	27
Selenium and Selenoprotein P Deficiency Correlates With Complications and Adverse Outcome After Major Trauma	27
COVID-19 Associated Hypercoagulability: Manifestations, Mechanisms, and Management	26
Users Guide to Pitfalls and Lessons Learned About HBOC-201 During Clinical Trials, Expanded Access, and Clinical Use in 1,701 Patients	26
A Review of Pathophysiology, Clinical Features, and Management Options of COVID-19 Associated Coagulopathy	26
Proenkephalin Compared to Conventional Methods to Assess Kidney Function in Critically Ill Sepsis Patients	26
Burn-Induced Coagulopathies: a Comprehensive Review	25
Heparin-Binding Protein as a Prognostic Biomarker of Sepsis and Disease Severity at the Emergency Department	25
Critically Ill COVID-19 Patients With Acute Kidney Injury Have Reduced Renal Blood Flow and Perfusion Despite Preserved Cardiac Function: A Case-Control Study Using Contrast-Enhanced Ultrasound	23
Hypoxia-Inducible Factor (HIF)-1α Promotes Inflammation and Injury Following Aspiration-Induced Lung Injury in Mice	23

Temporal Differential Expression of Physiomarkers Predicts Sepsis in Critically Ill Adults	23
Daily Changes in the Expression of Clock Genes in Sepsis and Their Relation with Sepsis Outcome and Urinary Excretion of 6-Sulfatoximelatonin	22
N-Acetylcysteine Ameliorates Gentamicin-Induced Nephrotoxicity by Enhancing Autophagy and Reducing Oxidative Damage in Miniature Pigs	22
The Diagnostic and Prognostic Value of suPAR in Patients with Sepsis: A Systematic Review and Meta-Analysis	22
Blockade Of PD-1 Attenuated Postsepsis Aspergillosis Via The Activation of IFN-γ and The Dampening of IL-10	22
Advanced Age Impairs Intestinal Antimicrobial Peptide Response and Worsens Fecal Microbiome Dysbiosis Following Burn Injury in Mice	21
Laboratory Markers of Acidosis and Mortality in Cardiogenic Shock: Developing a Definition of Hemometabolic Shock	21
Review of Existing Scoring Systems for Massive Blood Transfusion in Trauma Patients: Where Do We Stand?	21
Clinical Course of 195 Critically Ill COVID-19 Patients: A Retrospective Multicenter Study	21
Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice	21
Sphingosine-1-Phosphate Reduces Hemorrhagic Shock and Resuscitation-Induced Microvascular Leakage by Protecting Endothelial Mitochondrial Integrity	21
PINK1 Activation and Translocation to Mitochondria-Associated Membranes Mediates Mitophagy and Protects Against Hepatic Ischemia/Reperfusion Injury	21
Tissue-Resident Macrophages in the Control of Infection and Resolution of Inflammation	21
Hemophagocytic Lymphohistiocytosis in Critically Ill Patients	21
Perftoran (Vidaphor)—Introduction to Western Medicine	20
Fecal Microbiota Transplantation and Hydrocortisone Ameliorate Intestinal Barrier Dysfunction and Improve Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis	20
Mitochondrial Dysfunction is Associated With an Immune Paralysis Phenotype in Pediatric Sepsis	20
Feasibility and Clinical Outcome of Reboa in Patients with Impending Traumatic Cardiac Arrest	20
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study	20
Microcirculatory, Endothelial, and Inflammatory Responses in Critically Ill Patients With COVID-19 Are Distinct From Those Seen in Septic Shock: A Case Control Study	19
A New Echocardiographic Tool for Cardiac Output Evaluation: An Experimental Study	19
Antithrombin III Contributes to the Protective Effects of Fresh Frozen Plasma Following Hemorrhagic Shock by Preventing Syndecan-1 Shedding and Endothelial Barrier Disruption	19
Inhibition of Ferroptosis Attenuates Glutamate Excitotoxicity and Nuclear Autophagy in a CLP Septic Mouse Model	18
Plasma Angiopoietin-2/-1 Ratio is Elevated and Angiopoietin-2 Levels Correlate With Plasma Syndecan-1 Following Pediatric Trauma	18
Immunomodulatory and Therapeutic Effects of Mesenchymal Stem Cells on Organ Dysfunction in Sepsis	18
Complement as a Major Inducer of Harmful Events in Infectious Sepsis	18
sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions	18
Impaired B-Cell Maturation Contributes to Reduced B Cell Numbers and Poor Prognosis in Sepsis	18
Transfusion of Anaerobically or Conventionally Stored Blood After Hemorrhagic Shock	18
Hydrocortisone, Ascorbic Acid, and Thiamine (HAT) Therapy Decreases Oxidative Stress, Improves Cardiovascular Function, and Improves Survival in Murine Sepsis	18
Comparison of Associations Between Glucocorticoids Treatment and Mortality in COVID-19 Patients and SARS Patients: A Systematic Review and Meta-Analysis	18
Therapeutic Potential of B-1a Cells in COVID-19	18
Complex Feed-Forward and Feedback Mechanisms Underlie the Relationship Between Traumatic Brain Injury and the Gut–Microbiota–Brain Axis	18
Acute Inflammation in Traumatic Brain Injury and Polytrauma Patients Using Network Analysis	17
The Prognostic Value of Lactate in Cardiac Intensive Care Unit Patients With Cardiac Arrest and Shock	17
Overexpression of BCL-2 in the Intestinal Epithelium Prevents Sepsis-Induced Gut Barrier Dysfunction via Altering Tight Junction Protein Expression	17
Inhibition of Aerobic Glycolysis Promotes Neutrophil to Influx to the Infectious Site Via CXCR2 in Sepsis	17
Current Challenges in the Development of Acellular Hemoglobin Oxygen Carriers by Protein Engineering	17
Potential Immunotherapeutic Targets for Hypoxia Due to COVI-Flu	17
Cholecystokinin Modulates the Mucosal Inflammatory Response and Prevents the Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction	17
Severe COVID-19: Immunosuppression or Hyperinflammation?	17
IL-15 Improves Aging-Induced Persistent T Cell Exhaustion in Mouse Models of Repeated Sepsis	17
Complement Activation in Human Sepsis is Related to Sepsis-Induced Disseminated Intravascular Coagulation	17
Late Peaks of HMGB1 and Sepsis Outcome: Evidence For Synergy With Chronic Inflammatory Disorders	17
Presepsin Values Predict Septic Acute Kidney Injury, Acute Respiratory Distress Syndrome, Disseminated Intravascular Coagulation, and Shock	17
The Prognostic Usefulness of the Lactate/Albumin Ratio for Predicting Clinical Outcomes in Out-of-Hospital Cardiac Arrest: a Prospective, Multicenter Observational Study (koCARC) Study	16
Increased Intracranial Hemorrhage Amid Elevated Inflammatory Markers in Those With COVID-19 Supported With Extracorporeal Membrane Oxygenation	16
Cytokine Drizzle—The Rationale for Abandoning “Cytokine Storm”	16
Neutrophil Phenotypes and Functions in Trauma and Trauma-Related Sepsis	16
Norepinephrine vs Vasopressin: Which Vasopressor Should Be Discontinued First in Septic Shock? A Meta-Analysis	16

Microvascular Dysfunction in Patients with Critical Covid-19, a Pilot Study	16
Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model	16
Remote Intestinal Injury Early After Experimental Polytrauma and Hemorrhagic Shock	16
Sex- and Gender-Dependent Differences in Clinical and Preclinical Sepsis	16
Activation of AMP-Activated Protein Kinase by A769662 Ameliorates Sepsis-Induced Acute Lung Injury in Adult Mice	16
Platelet–Monocyte Aggregates: Understanding Mechanisms and Functions in Sepsis	16
The Warburg Effect Promotes Mitochondrial Injury Regulated by Uncoupling Protein-2 in Septic Acute Kidney Injury	15
TUDCA Ameliorates Liver Injury Via Activation of SIRT1–FXR Signaling in a Rat Hemorrhagic Shock Model	15
The Greater Omentum—A Vibrant and Enigmatic Immunologic Organ Involved in Injury and Infection Resolution	15
Autophagy Induction Ameliorates Inflammatory Responses in Intestinal Ischemia–Reperfusion Through Inhibiting NLRP3 Inflammasome Activation	15
Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia	15
Incidence, Patient Characteristics, Mode of Drug Delivery, and Outcomes of Septic Shock Patients Treated With Vasopressors in the Arise Trial	15
Tracking DO2 with Compensatory Reserve During Whole Blood Resuscitation in Baboons	15
Etomidate Attenuates the Ferroptosis in Myocardial Ischemia/Reperfusion Rat Model via Nrf2/HO-1 Pathway	14
Pyruvate-Driven Oxidative Phosphorylation is Downregulated in Sepsis-Induced Cardiomyopathy: A Study of Mitochondrial Proteome	14
A Prediction Model for Assessing Prognosis in Critically Ill Patients with Sepsis-associated Acute Kidney Injury	14
Risk Factors of Multidrug Resistant Pathogens Induced Infection in Severe Acute Pancreatitis	14
Phagocytosis–Inflammation Crosstalk in Sepsis: New Avenues for Therapeutic Intervention	14
Early Positive Fluid Balance is Associated with Mortality in Patients Treated with Veno-Arterial Extra Corporeal Membrane Oxygenation For Cardiogenic Shock: a Retrospective Cohort Study	14
Lactic Acidosis and the Role of Sodium Bicarbonate: A Narrative Opinion	14
Endothelial Dysfunction is Associated With Increased Incidence, Worsened Severity, and Prolonged Duration of Acute Kidney Injury After Severe Trauma	14
Circulating Syndecan-1 and Tissue Factor Pathway Inhibitor, Biomarkers of Endothelial Dysfunction, Predict Mortality in Burn Patients	14
Myocardial Edema: an Overlooked Mechanism of Septic Cardiomyopathy?	14
Temporal Changes in REBOA Utilization Practices are Associated With Increased Survival: an Analysis of the AORTA Registry	14
Inhibition of Lipolysis With Acipimox Attenuates Postburn White Adipose Tissue Browning and Hepatic Fat Infiltration	14
Perfluorocarbons: Knowledge Gained From Clinical Trials	14
Right Ventricular Function and Long-Term Outcome in Sepsis: A Retrospective Cohort Study	14
Postconditioning with Calreticulin Attenuates Myocardial Ischemia/Reperfusion Injury and Improves Autophagic Flux	14
Effect of Vasopressors on the Macro- and Microcirculation During Systemic Inflammation in Humans In Vivo	14
Complement Deposition on the Surface of RBC After Trauma Serves a Biomarker of Moderate Trauma Severity: A Prospective Study	14
Resuscitation From Hemorrhagic Shock With Fresh and Stored Blood and Polymerized Hemoglobin	13
Role of Von Willebrand Factor after Injury: It May Do More Than We Think	13
Does Fenoldopam Protect Kidney in Cardiac Surgery? A Systemic Review and Meta-Analysis With Trial Sequential Analysis	13
Function is Dissociated From Activation-Related Immunophenotype on Phagocytes From Patients With SIRS/Sepsis Syndrome	13
Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation	13
Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) for Use in Temporizing Intra-Abdominal and Pelvic Hemorrhage: Physiologic Sequelae and Considerations	13
Immunosuppression is Inappropriately Qualifying the Immune Status of Septic and SIRS Patients	13
Cardiac Dysfunction in Severely Burned Patients: Current Understanding of Etiology, Pathophysiology, and Treatment	12
Protein Compositions Changes of Circulating Microparticles in Patients With Valvular Heart Disease Subjected to Cardiac Surgery Contribute to Systemic Inflammatory Response and Disorder of Coagulation	12
Skeletal Muscle Interleukin-6 Contributes to the Innate Immune Response in Septic Mice	12
Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx	12
Rhabdomyolysis is Associated with In-Hospital Mortality in Patients with COVID-19	12
Thrombin Generation Following Severe Trauma: Mechanisms, Modulators, and Implications for Hemostasis and Thrombosis	12
Histone Deacetylase Inhibitors: A Novel Strategy in Trauma and Sepsis	12
The Colombian Experience in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): The Progression From a Large Caliber to a Low-Profile Device at a Level I Trauma Center	12
Lymphocyte Immunosuppression and Dysfunction Contributing to Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PICS)	12
Endovascular Resuscitation and Trauma Management (EVTM)—Practical Aspects and Implementation	12
Cirrhotic Patients Admitted to the ICU With Septic Shock: Factors Predicting Short and Long-Term Outcome	12
Nicotine Improves Survivability, Hypotension, and Impaired Adenosinergic Renal Vasodilations in Endotoxic Rats: Role of α7-nAChRs/HO-1 Pathway	12
Comparison Between Continuous and Intermittent Administration of Hydrocortisone During Septic Shock: A Randomized Controlled Clinical Trial	12
Shock Index and Postpartum Hemorrhage in Vaginal Deliveries: A Multicenter Retrospective Study	12
MIR-190B Alleviates Cell Autophagy and Burn-Induced Skeletal Muscle Wasting via Modulating PHLPP1/Akt/FoxO3A Signaling Pathway	12
Heparin Binding Protein for the Early Diagnosis and Prognosis of Sepsis in the Emergency Department: The Prompt Multicenter Study	12
Resuscitation Fluids in Septic Shock: A Network Meta-Analysis of Randomized Controlled Trials	12
Prehospital Point of Care Testing for the Early Detection of Shock and Prediction of Lifesaving Interventions	12
Sequential Changes of NLRP3 Inflammasome Activation in Sepsis and its Relationship With Death	12
Aerosol Exposure During Surgical Tracheotomy in SARS-CoV-2 Positive Patients	12
Methane-Rich Saline Protects Against Sepsis-Induced Liver Damage by Regulating the PPAR-γ/NF-κB Signaling Pathway	12
Gut Barrier Dysfunction Induced by Aggressive Fluid Resuscitation in Severe Acute Pancreatitis is Alleviated by Necroptosis Inhibition in Rats	12
Demographics, Treatments, and Outcomes of Acute Respiratory Distress Syndrome: the Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis, and Trauma (FORECAST) Stu	11
Effect of Combined Hydrocortisone, Ascorbic Acid and Thiamine for Patients with Sepsis and Septic Shock: A Systematic Review and Meta-Analysis	11
Mechanistic Studies of DNase I Activity: Impact of Heparin Variants and PAD4	11
HIF-1α and Hypoxia Responsive Genes are Differentially Expressed in Leukocytes from Survivors and Non-Survivors Patients during Clinical Sepsis	11
Relative Efficacies of HBOC-201 and Polyheme to Increase Oxygen Transport Compared to Blood and Crystalloids	11
Evaluating the Timeliness and Specificity of CD69, CD64, and CD25 as Biomarkers of Sepsis in Mice	11
The Role of Macrophage Migration Inhibitory Factor in Remote Ischemic Conditioning Induced Hepatoprotection in a Rodent Model of Liver Transplantation	11
Comparative Early Hemodynamic Profiles in Patients Presenting to the Emergency Department with Septic and Nonseptic Acute Circulatory Failure Using Focused Echocardiography	11
Severe Trauma and Hemorrhage Leads to Platelet Dysfunction and Changes in Cyclic Nucleotides in The Rat	11
Cardiac and Skeletal Muscle Myosin Exert Procoagulant Effects	11
Modulation of Endoplasmic Reticulum Stress Influences Ischemia-Reperfusion Injury After Hemorrhagic Shock	11
Hemodynamic Impact of Cardiovascular Antihypertensive Medications in Patients With Sepsis-Related Acute Circulatory Failure	11
Irisin Protects Against LPS-Stressed Cardiac Damage Through Inhibiting Inflammation, Apoptosis, and Pyroptosis	11
Effects of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis	11
Luteolin Suppresses Sepsis-Induced Cold-Inducible RNA-Binding Protein Production and Lung Injury in Neonatal Mice	11
Autotaxin Activity Predicts 30-Day Mortality in Sepsis Patients and Correlates With Platelet Count and Vascular Dysfunction	11
Muscle-Derived Mitochondrial Transplantation Reduces Inflammation, Enhances Bacterial Clearance, and Improves Survival in Sepsis	11
Complications of Hemorrhagic Shock and Massive Transfusion – A Comparison before and after the Damage Control Resuscitation ERA	11
MUC1 Mitigates Renal Injury and Inflammation in Endotoxin-Induced Acute Kidney Injury by Inhibiting the TLR4-MD2 Axis and Reducing Pro-inflammatory Macrophages Infiltration	11
CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis	11
Survival Rates and Biomarkers in a Large Animal Model of Traumatic Brain Injury Combined With Two Different Levels of Blood Loss	11

Potential Value of Presepsin Guidance in Shortening Antibiotic Therapy in Septic Patients: a Multicenter, Prospective Cohort Trial	11
MiR-433 Regulates Myocardial Ischemia Reperfusion Injury by Targeting NDRG4 Via the PI3K/Akt Pathway	10
Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice	10
High Central Venous-to-Arterial CO2 Difference is Associated With Poor Outcomes in Patients After Cardiac Surgery: A Propensity Score Analysis	10
Remote Ischemic Conditioning in Emergency Medicine—Clinical Frontiers and Research Opportunities	10
The Consequences of Aging On the Response to Injury and Critical Illness	10
Kinetics of Ringer's Solution in Extracellular Dehydration and Hemorrhage	10
S1PR1-Associated Molecular Signature Predicts Survival in Patients with Sepsis	10
Adipocytokine Profile Reveals Resistin Forming a Prognostic-Related Cytokine Network in the Acute Phase of Sepsis	10
Histone Deacetylase 7 Inhibition in a Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury	10
Serum Lactate and A Relative Change in Lactate as Predictors of Mortality in Patients With Cardiogenic Shock – Results from the Cardshock Study	10
Elevated Plasma Levels of Matrix Metalloproteinase-3 and Tissue-Inhibitor of Matrix Metalloproteinases-1 Associate With Organ Dysfunction and Mortality in Sepsis	10
A Peptide-Based Checkpoint Immunomodulator Alleviates Immune Dysfunction in Murine Polymicrobial Sepsis	10
Modulation of Peroxynitrite Reduces Norepinephrine Requirements in Ovine MRSA Septic Shock	10
Buprenorphine Markedly Elevates a Panel of Surrogate Markers in a Murine Model of Sepsis	10
Extracorporeal Hemoadsorption: An Option for COVID-19-Associated Cytokine Storm Syndrome	10
Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis	10
Dodecafluoropentane Emulsion (DDFPE) as a Resuscitation Fluid for Treatment of Hemorrhagic Shock and Traumatic Brain Injury: A Review	10
Prognosis and Risk Factors of Sepsis Patients in Chinese ICUs: A Retrospective Analysis of a Cohort Database	10
Fibrinolysis Shutdown and Thrombosis in a COVID-19 ICU	10
Sepsis Induces Deregulation of IL-13 Production and PD-1 Expression in Lung Group 2 Innate Lymphoid Cells	10
Cell–Cell Interaction Mechanisms in Acute Lung Injury	10
Effect of Coagulation Factor Concentrates on Markers of Endothelial Cell Damage in Experimental Hemorrhagic Shock	10
The Cardiac Physiology Underpinning Exsanguination Cardiac Arrest: Targets for Endovascular Resuscitation	10
Monophosphoryl Lipid a Attenuates Multiorgan Dysfunction During Post-Burn Pseudomonas Aeruginosa Pneumonia in Sheep	10
Tenascin C Plasma Levels in Critically Ill Patients with or Without Sepsis: A Multicenter Observational Study	10
Therapeutic Effects of Hyaluronic Acid in Peritonitis-Induced Sepsis in Mice	10
Population-Specific Metabolic Alterations in Professional Antigen-Presenting Cells Contribute to Sepsis-Associated Immunosuppression	10
Evaluation of the Initiation Timing of Hydrocortisone in Adult Patients With Septic Shock	9
The Association Between ABO Blood Type and Mortality Among Severely Injured Trauma Patients	9
NLRP3 Inflammasome Mediates Neurodegeneration in Rats with Chronic Neuropathic Pain	9
Operative Trauma and Blood Loss — Impact on Tumor Growth and Recurrence	9
H2S as a Therapeutic Adjuvant Against COVID-19: Why and How?	9
Exploring Clinically-Relevant Experimental Models of Neonatal Shock and Necrotizing Enterocolitis	9
The IL-33-ST2 Pathway Contributes to Ventilator-Induced Lung Injury in Septic Mice in a Tidal Volume-Dependent Manner	9
Macrophage Efferocytosis in Cardiac Pathophysiology and Repair	9
Thermoneutral Housing Temperature Improves Survival in a Murine Model of Polymicrobial Peritonitis	9
The Prognostic Value of Presepsin for Sepsis in Abdominal Surgery: A Prospective Study	9
Pharmacological and Genetic Inhibition of Translocator Protein 18 kDa Ameliorated Neuroinflammation in Murine Endotoxemia Model	9
Acute Lung Injury in Critically Ill Patients: Actin-Scavenger Gelsolin Signals Prolonged Respiratory Failure	9
The Role of TEG and ROTEM in Damage Control Resuscitation	9
Inhibition of PAR-2 Attenuates Neuroinflammation and Improves Short-Term Neurocognitive Functions Via ERK1/2 Signaling Following Asphyxia-Induced Cardiac Arrest in Rats	9
Accuracy Comparison Between Age-Adapted SOFA and SIRS in Predicting in-Hospital Mortality of Infected Children at China's PICU	9
High-Sensitivity Troponin T Predicts Postoperative Cardiogenic Shock Requiring Mechanical Circulatory Support in Patients With Valve Disease	9
Activation of Hypoxia-Inducible Factor-1α Via Succinate Dehydrogenase Pathway During Acute Lung Injury Induced by Trauma/Hemorrhagic Shock	9
Early Peritoneal Dialysis Ameliorates Blast Lung Injury by Alleviating Pulmonary Edema and Inflammation	9
Systemic and Cardiac Alterations After Long Bone Fracture	9
Hepcidin Alleviates LPS-Induced ARDS by Regulating the Ferritin-Mediated Suppression of Ferroptosis	9
Catecholamines Induce Endoplasmic Reticulum Stress Via Both Alpha and Beta Receptors	9
Mesenchymal Stem/Stromal Cells Increase Cardiac MIR-187-3P Expression in Polymicrobial Animal Model of Sepsis	9
Carbon Monoxide-Releasing Molecule-3 Ameliorates Acute Lung Injury in a Model of Hemorrhagic Shock and Resuscitation: Roles of p38MAPK Signaling Pathway	9
A New Time-Window Prediction Model For Traumatic Hemorrhagic Shock Based on Interpretable Machine Learning	9
Selective Prehospital Advanced Resuscitative Care – Developing a Strategy to Prevent Prehospital Deaths From Noncompressible Torso Hemorrhage	9
Effects of Sanguinate on Systemic and Microcirculatory Variables in a Model of Prolonged Hemorrhagic Shock	9
Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma	9
Mechanical Circulatory Support in Refractory Vasodilatory Septic Shock: a Randomized Controlled Porcine Study	8
The Prognostic Value of Prehospital Blood Lactate Levels to Predict Early Mortality in Acute Cardiovascular Disease	8
Regulatory Roles of Human Surfactant Protein B Variants on Genetic Susceptibility to Pseudomonas Aeruginosa Pneumonia-Induced Sepsis	8
The Hematopoietic Stem/Progenitor Cell Response to Hemorrhage, Injury, and Sepsis: A Review of Pathophysiology	8
Overexpressed lncRNA AC068039.4 Contributes to Proliferation and Cell Cycle Progression of Pulmonary Artery Smooth Muscle Cells Via Sponging miR-26a-5p/TRPC6 in Hypoxic Pulmonary Arterial Hypertension	8
Comparing Mortality Prediction by Quick Sequential Organ Failure Assessment with Emergency Physician Judgment	8
Delta Neutrophil Index for the Prediction of the Development of Sepsis-Induced Acute Kidney Injury in the Emergency Department	8
Airway Epithelial Hepcidin Coordinates Lung Macrophages and Immunity Against Bacterial Pneumonia	8
Hemorrhagic Shock and Resuscitation Causes Glycocalyx Shedding and Endothelial Oxidative Stress Preferentially in the Lung and Intestinal Vasculature	8
The Effect of Burn Resuscitation Volumes on the Gut Microbiome in a Swine Model	8
Involvement of NF-κB1 and the Non-canonical NF-κB Signaling Pathway in the Pathogenesis of Acute Kidney Injury in Shiga-toxin-2-induced Hemolytic-uremic Syndrome in Mice	8
Cardiogenic Shock Complicating ST-Segment Elevation Myocardial Infarction: An 18-Year Analysis of Temporal Trends, Epidemiology, Management, and Outcomes	8
Endotoxin Removal in Septic Shock with the Alteco LPS Adsorber Was Safe But Showed no Benefit Compared to Placebo in the Double-Blind Randomized Controlled Trial—the Asset Study	8
Early Differential Value of Plasma Presepsin on Infection of Trauma Patients	8
Sepsis Increases Muscle Proteolysis in Severely Burned Adults, but Does not Impact Whole-Body Lipid or Carbohydrate Kinetics	8
Findings and Prognostic Value of Lung Ultrasonography in Coronal Virus Disease 2019 (COVID-19) Pneumonia	8
Myocardial Electrical Remodeling and the Arrhythmogenic Substrate in Hemorrhagic Shock-Induced Heart: Anti-Arrhythmogenic Effect of Liposome-Encapsulated Hemoglobin (HbV) on the Myocardium	8
Specific Pathogen-Free Animals for Civilian and Military Trauma: a Cautionary Note in the Translation of New Drug Therapies	8
Admission Lactate and Base Deficit in Predicting Outcomes of Pediatric Trauma	8
Activation of the XBP1s/O-GlcNAcylation Pathway Improves Functional Outcome After Cardiac Arrest and Resuscitation in Young and Aged Mice	8
Early Hemoglobin Status as a Predictor of Long-Term Mortality for Sepsis Patients in Intensive Care Units	8
Effects of Systemic Hypothermia on Microcirculation in Conditions of Hemodynamic Stability and in Hemorrhagic Shock	8
Microvascular and Systemic Impact of Resuscitation with PEGylated Carboxyhemoglobin-Based Oxygen Carrier or Hetastarch in a Rat Model of Transient Hemorrhagic Shock	8
Sulforaphane-Dependent Up-Regulation of NRF2 Activity Alleviates Both Systemic Inflammatory Response and Lung Injury After Hemorrhagic Shock/Resuscitation in Mice	8
Early Axonal Injury and Delayed Cytotoxic Cerebral Edema are Associated with Microglial Activation in a Mouse Model of Sepsis	8
Memantine Alleviates Acute Lung Injury Via Inhibiting Macrophage Pyroptosis	8
Early Sequential Microcirculation Assessment In Shocked Patients as a Predictor of Outcome: A Prospective Observational Cohort Study	8
Low Microcirculatory Perfused Vessel Density and High Heterogeneity are Associated With Increased Intensity and Duration of Lactic Acidosis After Cardiac Surgery with Cardiopulmonary Bypass	8