OOIR: Observatory of International Research

Papers

(The median citation count of Drug Delivery is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application	174
Milk exosomes-mediated miR-31-5p delivery accelerates diabetic wound healing through promoting angiogenesis	86
Preservation of small extracellular vesicles for functional analysis and therapeutic applications: a comparative evaluation of storage conditions	72
Metal nanoparticles as a promising technology in targeted cancer treatment	71
Disitamab vedotin: a novel antibody-drug conjugates for cancer therapy	68
Preserving extracellular vesicles for biomedical applications: consideration of storage stability before and after isolation	61
Cell-derived biomimetic nanocarriers for targeted cancer therapy: cell membranes and extracellular vesicles	59
Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review	55
Exosome-transmitted circVMP1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting miR-524-5p-METTL3/SOX2 axis	55
Progress in the development of stabilization strategies for nanocrystal preparations	54
Preparation and characterization of 2-hydroxyethyl starch microparticles for co-delivery of multiple bioactive agents	53
Drug delivery of amoxicillin molecule as a suggested treatment for covid-19 implementing functionalized mesoporous SBA-15 with aminopropyl groups	51
Poly(lactic-co-glycolic acid) microsphere production based on quality by design: a review	51
Formulation, characterization, and cellular toxicity assessment of tamoxifen-loaded silk fibroin nanoparticles in breast cancer	49
Application of chitosan/alginate nanoparticle in oral drug delivery systems: prospects and challenges	49
Recent advances in the local antibiotics delivery systems for management of osteomyelitis	48
Network pharmacology and experimental investigation ofRhizoma polygonatiextract targeted kinase with herbzyme activity for potent drug delivery	46
Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage	44
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy	42
Preparation and use of nanogels as carriers of drugs	42
Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis	41
Functional ligands for improving anticancer drug therapy: current status and applications to drug delivery systems	40
Recent advances in cell membrane-camouflaged nanoparticles for inflammation therapy	39
Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy	39
Enrofloxacin/florfenicol loaded cyclodextrin metal-organic-framework for drug delivery and controlled release	38

Exosome loaded genipin crosslinked hydrogel facilitates full thickness cutaneous wound healing in rat animal model	36
Targeted treatment for osteoarthritis: drugs and delivery system	36
Development of L-carnosine functionalized iron oxide nanoparticles loaded with dexamethasone for simultaneous therapeutic potential of blood brain barrier crossing and ischemic stroke treatment	36
Hepatic stellate cell reprogramming via exosome-mediated CRISPR/dCas9-VP64 delivery	34
Stimuli-responsive drug delivery systems for head and neck cancer therapy	34
Structural and biological investigation of chitosan/hyaluronic acid with silanized-hydroxypropyl methylcellulose as an injectable reinforced interpenetrating network hydrogel for cartilage tissue engi	34
Layer-by-Layer assembled nano-drug delivery systems for cancer treatment	32
Self-emulsifying drug delivery systems: a novel approach to deliver drugs	31
Docetaxel-loaded exosomes for targeting non-small cell lung cancer: preparation and evaluation in vitro and in vivo	30
Targeted delivery of quercetin by biotinylated mixed micelles for non-small cell lung cancer treatment	30
Topical delivery of l-ascorbic acid spanlastics for stability enhancement and treatment of UVB induced damaged skin	30
Thymoquinone-entrapped chitosan-modified nanoparticles: formulation optimization to preclinical bioavailability assessments	29
Enhancement of oral bioavailability of quercetin by metabolic inhibitory nanosuspensions compared to conventional nanosuspensions	29
β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation	28
Nanodelivery of essential oils as efficient tools against antimicrobial resistance: a review of the type and physical-chemical properties of the delivery systems and applications	28
Targeted therapy of rheumatoid arthritis via macrophage repolarization	27
Targeted nano-delivery strategies for facilitating thrombolysis treatment in ischemic stroke	27
Gemcitabine cationic polymeric nanoparticles against ovarian cancer: formulation, characterization, and targeted drug delivery	27
Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology	27
Combined and targeted drugs delivery system for colorectal cancer treatment: Conatumumab decorated, reactive oxygen species sensitive irinotecan prodrug and quercetin co-loaded nanostructured lipid ca	27
Anti-lung cancer effect of paclitaxel solid lipid nanoparticles delivery system with curcumin as co-loading partner in vitro and in vivo	27
Novel cubosome based system for ocular delivery of acetazolamide	26
Novel chitosan and bacterial cellulose biocomposites tailored with polymeric nanoparticles for modern wound dressing development	26
Extracellular vesicles: emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy	26
Recent advances in anti-multidrug resistance for nano-drug delivery system	26
Statistical optimization of bile salt deployed nanovesicles as a potential platform for oral delivery of piperine: accentuated antiviral and anti-inflammatory activity in MERS-CoV challenged mice	26
Utilization of PEGylated cerosomes for effective topical delivery of fenticonazole nitrate: in-vitro characterization, statistical optimization, and in-vivo assessment	26
Electrospun multifunctional nanofibrous mats loaded with bioactive anemoside B4 for accelerated wound healing in diabetic mice	25
Sonodynamical reversion of immunosuppressive microenvironment in prostate cancer via engineered exosomes	25
Intranasal administration of dauricine loaded on graphene oxide: multi-target therapy for Alzheimer's disease	25
Dextran sulfate-based MMP-2 enzyme-sensitive SR-A receptor targeting nanomicelles for the treatment of rheumatoid arthritis	25
3D-printed implantable devices with biodegradable rate-controlling membrane for sustained delivery of hydrophobic drugs	24
Polymeric versus lipid nanocapsules for miconazole nitrate enhanced topical delivery: in vitro and ex vivo evaluation	24
Construction of pH-sensitive targeted micelle system co-delivery with curcumin and dasatinib and evaluation of anti-liver cancer	24
Combination prostate cancer therapy: Prostate-specific membranes antigen targeted, pH-sensitive nanoparticles loaded with doxorubicin and tanshinone	24
The optimized drug delivery systems of treating cancer bone metastatic osteolysis with nanomaterials	24
Development and optimization of curcumin analog nano-bilosomes using 2¹.3¹full factorial design for anti-tumor profiles improvement in human hepatocellular carcinoma:in-vitro<	23
Cubogel as potential platform for glaucoma management	23
Development of omega-3 loxoprofen-loaded nanoemulsion to limit the side effect associated with NSAIDs in treatment of tooth pain	23
Hybrid thermosensitive-mucoadhesive in situ forming gels for enhanced corneal wound healing effect of L-carnosine	23
Amplification of anticancer efficacy by co-delivery of doxorubicin and lonidamine with extracellular vesicles	23
Co-delivery of paclitaxel (PTX) and docosahexaenoic acid (DHA) by targeting lipid nanoemulsions for cancer therapy	22
Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization and in vivo evaluat	22
An efficient enzyme-triggered controlled release system for colon-targeted oral delivery to combat dextran sodium sulfate (DSS)-induced colitis in mice	22
From blood to brain: blood cell-based biomimetic drug delivery systems	22
Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment	21
Combined delivery of salinomycin and docetaxel by dual-targeting gelatinase nanoparticles effectively inhibits cervical cancer cells and cancer stem cells	21
Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery	21
Synthesis of nanocapsules blended polymeric hydrogel loaded with bupivacaine drug delivery system for local anesthetics and pain management	21
A detailed insight of the tumor targeting using nanocarrier drug delivery system	21

Effect of pH-sensitive nanoparticles on inhibiting oral biofilms	21
Delivery of human natural killer cell-derived exosomes for liver cancer therapy: an in vivo study in subcutaneous and orthotopic animal models	21
Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy	20
Hyaluronan-modified transfersomes based hydrogel for enhanced transdermal delivery of indomethacin	20
Manganese-containing polydopamine nanoparticles as theranostic agents for magnetic resonance imaging and photothermal/chemodynamic combined ferroptosis therapy treating gastric cancer	20
Flexible nano-liposomes-based transdermal hydrogel for targeted delivery of dexamethasone for rheumatoid arthritis therapy	19
Icaritin-loaded PLGA nanoparticles activate immunogenic cell death and facilitate tumor recruitment in mice with gastric cancer	19
Fabrication of silver nanoparticles/gelatin hydrogel system for bone regeneration and fracture treatment	19
Olive oil and clove oil-based nanoemulsion for topical delivery of terbinafine hydrochloride: in vitro and ex vivo evaluation	19
Anti-inflammatory and antioxidant effects of nanoformulations composed of metal-organic frameworks delivering rutin and/or piperine natural agents	19
pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable and self-amplification drug release for combating multidrug resistance cancer	19
Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability	19
Aqueous core epigallocatechin gallate PLGA nanocapsules: characterization, antibacterial activity against uropathogens, and in vivo reno-protective effect in cisplatin induced nephrotoxicity	19
Model-based optimized steering and focusing of local magnetic particle concentrations for targeted drug delivery	19
Management of recurrent aphthous ulcers exploiting polymer-based Muco-adhesive sponges: in-vitro and in-vivo evaluation	18
Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury	18
Recent progress in nanotechnology-based drug carriers for resveratrol delivery	18
Nanocubosomal based in situ gel loaded with natamycin for ocular fungal diseases: development, optimization, in-vitro, and in-vivo assessment	18
PLGA sustained-release microspheres loaded with an insoluble small-molecule drug: microfluidic-based preparation, optimization, characterization, and evaluation in vitro and in vivo	18
Green synthesis of gold nanoparticles from Dendrobium officinale and its anticancer effect on liver cancer	18
Nanophyto-gel against multi-drug resistant Pseudomonas aeruginosa burn wound infection	18
Pullulan based derivatives: synthesis, enhanced physicochemical properties, and applications	18
Microbubble drug conjugate and focused ultrasound blood brain barrier delivery of AAV-2 SIRT-3	18
Nanocrystals based pulmonary inhalation delivery system: advance and challenge	18
Simulating drug penetration during hyperthermic intraperitoneal chemotherapy	18
Cepharanthine loaded nanoparticles coated with macrophage membranes for lung inflammation therapy	17
The Port Delivery System with ranibizumab: a new paradigm for long-acting retinal drug delivery	17
Charge-reversal nanomedicine based on black phosphorus for the development of A Novel photothermal therapy of oral cancer	17
Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects	17
Nanotechnological approach to delivering nutraceuticals as promising drug candidates for the treatment of atherosclerosis	17
Development, optimization and characterization of nanoemulsion loaded with clove oil-naftifine antifungal for the management of tinea	17
Brain targeting efficiency of intranasal clozapine-loaded mixed micelles following radio labeling with Technetium-99m	17
Novel hyaluronic acid oligosaccharide-loaded and CD44v6-targeting oxaliplatin nanoparticles for the treatment of colorectal cancer	17
Alginate nanogels-based thermosensitive hydrogel to improve antidepressant-like effects of albiflorin via intranasal delivery	17
Preparation and characterization of paclitaxel palmitate albumin nanoparticles with high loading efficacy: an in vitro and in vivo anti-tumor study in mouse models	17
Self-assembling peptides-based nano-cargos for targeted chemotherapy and immunotherapy of tumors: recent developments, challenges, and future perspectives	17
Ligand-modified homologous targeted cancer cell membrane biomimetic nanostructured lipid carriers for glioma therapy	17
Alginate-based aerogels as wound dressings for efficient bacterial capture and enhanced antibacterial photodynamic therapy	16
Facile surface functional polyetheretherketone with antibacterial and immunoregulatory activities for enhanced regeneration toward bacterium-infected bone destruction	16
Monoclonal antibody as a targeting mediator for nanoparticle targeted delivery system for lung cancer	16
Chitosan-coated bovine serum albumin nanoparticles for topical tetrandrine delivery in glaucoma: in vitro and in vivo assessment	16
Multifunctional liposome for photoacoustic/ultrasound imaging-guided chemo/photothermal retinoblastoma therapy	16
Functionalized chitosan nanoparticles for cutaneous delivery of a skin whitening agent: an approach to clinically augment the therapeutic efficacy for melasma treatment	16
Silk fibroin hydrogel containing Sesbania sesban L. extract for rheumatoid arthritis treatment	16
Lipidic cubic-phase leflunomide nanoparticles (cubosomes) as a potential tool for breast cancer management	16
Sorafenib-loaded nanostructured lipid carriers for topical ocular therapy of corneal neovascularization: development, in-vitro and in vivo study	16
Improved anticancer activity of betulinic acid on breast cancer through a grafted copolymer-based micelles system	16
RPE-derived exosomes rescue the photoreceptors during retina degeneration: an intraocular approach to deliver exosomes into the subretinal space	16
Low-density lipoprotein nanomedicines: mechanisms of targeting, biology, and theranostic potential	16
Local drug delivery using poly(lactic-co-glycolic acid) nanoparticles in thermosensitive gels for inner ear disease treatment	16
Bone tumors effective therapy through functionalized hydrogels: current developments and future expectations	16
Exosome mimetics derived from bone marrow mesenchymal stem cells deliver doxorubicin to osteosarcoma in vitro and in vivo	16
Hydrogels for localized chemotherapy of liver cancer: a possible strategy for improved and safe liver cancer treatment	16
GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases	16
Chitosan-modified hollow manganese dioxide nanoparticles loaded with resveratrol for the treatment of spinal cord injury	15
Targeted co-delivery biomimetic nanoparticles reverse macrophage polarization for enhanced rheumatoid arthritis therapy	15
Iodinated cyanine dye-based nanosystem for synergistic phototherapy and hypoxia-activated bioreductive therapy	15
D-optimal mixture design for optimization of topical dapsone niosomes: in vitro characterization and in vivo activity against Cutibacterium acnes	15
Docetaxel loaded mPEG-PLA nanoparticles for sarcoma therapy: preparation, characterization, pharmacokinetics, and anti-tumor efficacy	15
Ultrasound-sensitive siRNA-loaded nanobubbles fabrication and antagonism in drug resistance for NSCLC	15
Star polyester-based folate acid-targeting nanoparticles for doxorubicin and curcumin co-delivery to combat multidrug-resistant breast cancer	15
Enhancing thein vitroandin vivoactivity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules	15
Oral gel loaded with penciclovir–lavender oil nanoemulsion to enhance bioavailability and alleviate pain associated with herpes labialis	15
Design and optimization of cranberry extract loaded bile salt augmented liposomes for targeting of MCP-1/STAT3/VEGF signaling pathway in DMN-intoxicated liver in rats	15
GSH-responsive poly-resveratrol based nanoparticles for effective drug delivery and reversing multidrug resistance	15
In vitro and in vivo evaluation of self-assembled chitosan nanoparticles selectively overcoming hepatocellular carcinoma via asialoglycoprotein receptor	15
Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo assessments	15
Luteolin-loaded exosomes derived from bone marrow mesenchymal stem cells: a promising therapy for liver fibrosis	15
Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD⁺ bioavailability and attenuated cardiac ischemia/reperfusion injury in mice	14
Dasatinib self-assembled nanoparticles decorated with hyaluronic acid for targeted treatment of tumors to overcome multidrug resistance	14
Optimization of process parameters for fabrication of electrospun nanofibers containing neomycin sulfate and Malva sylvestris extract for a better diabetic wound healing	14
Celastrol-conjugated chitosan oligosaccharide for the treatment of pancreatic cancer	14
A pH-responsive complex based on supramolecular organic framework for drug-resistant breast cancer therapy	14
The most promising microneedle device: present and future of hyaluronic acid microneedle patch	14
Carbopol emulgel loaded with ebastine for urticaria: development, characterization, in vitro and in vivo evaluation	14
Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles	14
Selective delivery of curcumin to breast cancer cells by self-targeting apoferritin nanocages with pH-responsive and low toxicity	14
Thermo-responsive injectable naringin-loaded hydrogel polymerised sodium alginate/bioglass delivery for articular cartilage	14
Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats	14
Topical anesthetic and pain relief using penetration enhancer and transcriptional transactivator peptide multi-decorated nanostructured lipid carriers	14

Anti-tumor effect of local injectable hydrogel-loaded endostatin alone and in combination with radiotherapy for lung cancer	13
Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design	13
Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation	13
Clinical comparative study of optimized metronidazole loaded lipid nanocarrier vaginal emulgel for management of bacterial vaginosis and its recurrence	13
Development, optimization, and evaluation of a nanostructured lipid carrier of sesame oil loaded with miconazole for the treatment of oral candidiasis	13
Compression-coated pulsatile chronomodulated therapeutic system: QbD assisted optimization	13
Oxaliplatin-loaded nanoemulsion containingTeucrium poliumL. essential oil induces apoptosis in Colon cancer cell lines through ROS-mediated pathway	13
Pulmonary delivery of resveratrol-β-cyclodextrin inclusion complexes for the prevention of zinc chloride smoke-induced acute lung injury	13
Stimuli-sensitive nano-drug delivery with programmable size changes to enhance accumulation of therapeutic agents in tumors	13
Aging erythrocyte membranes as biomimetic nanometer carriers of liver-targeting chromium poisoning treatment	13
Multimodal imaging and photothermal synergistic immunotherapy of retinoblastoma with tuftsin-loaded carbonized MOF nanoparticles	13
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells	13
In vitro and in vivo antitumor effects of lupeol-loaded galactosylated liposomes	13
Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films	13
Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery	13
Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis	13
Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation	13
In silico identification and experimental validation of cellular uptake by a new cell penetrating peptide P1 derived from MARCKS	13
Dissolving microneedle patch-assisted transdermal delivery of methotrexate improve the therapeutic efficacy of rheumatoid arthritis	12
Development of nanocubosomes co-loaded with dual anticancer agents curcumin and temozolomide for effective colon cancer therapy	12
Lipid bubbles combined with low-intensity ultrasound enhance the intratumoral accumulation and antitumor effect of pegylated liposomal doxorubicin in vivo	12
Targeting delivery and minimizing epidermal diffusion of tranexamic acid by hyaluronic acid-coated liposome nanogels for topical hyperpigmentation treatment	12
Efficacy and safety of novel-targeted drugs in the treatment of pulmonary arterial hypertension: a Bayesian network meta-analysis	12
Synthesis of dual-stimuli responsive metal organic framework-coated iridium oxide nanocomposite functionalized with tumor targeting albumin-folate for synergistic photodynamic/photothermal cancer ther	12
Enhanced oral bioavailability of koumine by complexation with hydroxypropyl-β-cyclodextrin: preparation, optimization, ex vivo and in vivo characterization	12
Emerging strategies in nanotechnology to treat respiratory tract infections: realizing current trends for future clinical perspectives	12
Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation, in vitro characterization, and in vivo pharmacodynamic evalua	12
Development of a naringenin microemulsion as a prospective ophthalmic delivery system for the treatment of corneal neovascularization: in vitro and in vivo evaluation	12
A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration	12
RETRACTED ARTICLE: Cerium oxide nanoparticle-loaded polyvinyl alcohol nanogels delivery for wound healing care systems on surgery	12
Repurposing ibuprofen-loaded microemulsion for the management of Alzheimer’s disease: evidence of potential intranasal brain targeting	12
Fenticonazole nitrate loaded trans-novasomes for effective management of tinea corporis: design characterization, in silico study, and exploratory clinical appraisal	12
Folate-functionalized SMMC-7721 liver cancer cell membrane-cloaked paclitaxel nanocrystals for targeted chemotherapy of hepatoma	12
Magnesium ascorbyl phosphate vesicular carriers for topical delivery; preparation, in-vitro and ex-vivo evaluation, factorial optimization and clinical assessment in melasma patients	12
Scalable flibanserin nanocrystal-based novel sublingual platform for female hypoactive sexual desire disorder: engineering, optimization adopting the desirability function approach and in vivo	12
Co-delivery of sorafenib and crizotinib encapsulated with polymeric nanoparticles for the treatment of in vivo lung cancer animal model	12
UTMD promoted local delivery of miR-34a-mimic for ovarian cancer therapy	12
Nanotransethosomes for enhanced transdermal delivery of mangiferin against rheumatoid arthritis: formulation, characterization, invivo pharmacokinetic and pharmacodynamic evaluation	12
Modification of sodium aescinate into a safer, more stable and effective water-soluble drug by liposome-encapsulation: anin vitroandin vivostudy	11
Lipid-based nano-formulation platform for eplerenone oral delivery as a potential treatment of chronic central serous chorioretinopathy: in-vitro optimization and ex-vivo assessment	11
Targeted inhibition of methicillin-resistant Staphylococcus aureus biofilm formation by a graphene oxide-loaded aptamer/berberine bifunctional complex	11
Microneedle mediated transdermal delivery of β-sitosterol loaded nanostructured lipid nanoparticles for androgenic alopecia	11
Recent advances in drug delivery systems for targeting brain tumors	11
Co-delivery of amphotericin B and pentamidine loaded niosomal gel for the treatment of Cutaneous leishmaniasis	11
A novel redox-responsive ursolic acid polymeric prodrug delivery system for osteosarcoma therapy	11
Radiotherapy-induced enrichment of EGF-modified doxorubicin nanoparticles enhances the therapeutic outcome of lung cancer	11
Microfluidic-based fabrication and characterization of drug-loaded PLGA magnetic microspheres with tunable shell thickness	11
cRGD peptide-conjugated polyethylenimine-based lipid nanoparticle for intracellular delivery of siRNA in hepatocarcinoma therapy	11
Effect and mechanism of paclitaxel loaded on magnetic Fe ₃ O ₄ @mSiO ₂ -NH ₂	11
Formulation and evaluation of butenafine loaded PLGA-nanoparticulate laden chitosan nano gel	11
Membrane protein-chimeric liposome-mediated delivery of triptolide for targeted hepatocellular carcinoma therapy	11
Preparation of PEG/ZIF-8@HF drug delivery system for melanoma treatment via oral administration	11
‘Mito-Bomb’: a novel mitochondria-targeting nanosystem for ferroptosis-boosted sonodynamic antitumor therapy	11
Development of local anesthetic drug delivery system by administration of organo-silica nanoformulations under ultrasound stimuli: in vitro and in vivo investigations	11
Assessment of efficacy and safety by CalliSpheres versus HepaSpheres for drug-eluting bead transarterial chemoembolization in unresectable large hepatocellular carcinoma patients	11
Development of surface modified bilosomes for the oral delivery of quercetin: optimization, characterization in-vitro antioxidant, antimicrobial, and cytotoxicity study	11
Construction of iron-mineralized black phosphorene nanosheet to combinate chemodynamic therapy and photothermal therapy	10
Theoretical model for the diclofenac release from PEGylated chitosan hydrogels	10
[²²³Ra] RaCl₂ nanomicelles showed potent effect against osteosarcoma: targeted alpha therapy in the nanotechnology era	10
Development and optimization of sitagliptin and dapagliflozin loaded oral self-nanoemulsifying formulation against type 2 diabetes mellitus	10
Liver-targeted delivery of asiatic acid nanostructured lipid carrier for the treatment of liver fibrosis	10
A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis	10
Formulation of the novel structure curcumin derivative–loaded solid lipid nanoparticles: synthesis, optimization, characterization and anti-tumor activity screening in vitro	10
Design of hydroxy-α-sanshool loaded nanostructured lipid carriers as a potential local anesthetic	10
Transdermal delivery of inflammatory factors regulated drugs for rheumatoid arthritis	10
The efficacy of Origanum majorana nanocubosomal systems in ameliorating submandibular salivary gland alterations in streptozotocin-induced diabetic rats	10
Cyclodextrin metal-organic framework as vaccine adjuvants enhances immune responses	10
Hyaluronic acid-modified redox-sensitive hybrid nanocomplex loading with siRNA for non-small-cell lung carcinoma therapy	10
A novel dendritic mesoporous silica based sustained hydrogen sulfide donor for the alleviation of adjuvant-induced inflammation in rats	10
Eplerenone nanocrystals engineered by controlled crystallization for enhanced oral bioavailability	10
Layer-by-layer coated hybrid nanoparticles with pH-sensitivity for drug delivery to treat acute lung infection	10
The discovery of berberine erythrocyte-hemoglobin self-assembly delivery system: a neglected carrier underlying its pharmacokinetics	10
Pitavastatin-loaded bilosomes for oral treatment of hepatocellular carcinoma: a repurposing approach	10
Aptamer-mediated hollow MnO ₂ for targeting the delivery of sorafenib	10
A spatiotemporal computational model of focused ultrasound heat-induced nano-sized drug delivery system in solid tumors	10
Recent progress in the development of nanomaterials targeting multiple cancer metabolic pathways: a review of mechanistic approaches for cancer treatment	10
Unraveling enhanced brain delivery of paliperidone-loaded lipid nanoconstructs: pharmacokinetic, behavioral, biochemical, and histological aspects	10
Novel optimized drug delivery systems for enhancing spinal cord injury repair in rats	10
Polysialic acid-functionalized liposomes for efficient honokiol delivery to inhibit breast cancer growth and metastasis	10
Lysosome activable polymeric vorinostat encapsulating PD-L1KD for a combination of HDACi and immunotherapy	10
Enzyme-triggered- and tumor-targeted delivery with tunable, methacrylated poly(ethylene glycols) and hyaluronic acid hybrid nanogels	10
Inflammation-targeted cannabidiol-loaded nanomicelles for enhanced oral mucositis treatment	9
Formulation of novel niosomal repaglinide chewable tablets using coprocessed excipients: in vitro characterization, optimization and enhanced hypoglycemic activity in rats	9
Evaluation of the hepatoprotective effect of naringenin loaded nanoparticles against acetaminophen overdose toxicity	9
Green synthesis and characterization of gold nanoparticles from Pholiota adiposa and their anticancer effects on hepatic carcinoma	9
Transdermal delivery of triptolide–phospholipid complex to treat rheumatoid arthritis	9
GRP78-targeted and doxorubicin-loaded nanodroplets combined with ultrasound: a potential novel theranostics for castration-resistant prostate cancer	9
ROS-responsive dimeric prodrug-based nanomedicine targeted therapy for gastric cancer	9
Acute myocardial infarction therapy: in vitro and in vivo evaluation of atrial natriuretic peptide and triphenylphosphonium dual ligands modified, baicalin-loaded nanoparticulate system	9
Preparation of baicalin-loaded ligand-modified nanoparticles for nose-to-brain delivery for neuroprotection in cerebral ischemia	9
Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imagin	9
Gelatin hydrogel/contact lens composites as rutin delivery systems for promoting corneal wound healing	9
Facile design of lidocaine-loaded polymeric hydrogel to persuade effects of local anesthesia drug delivery system: complete in vitro and in vivo toxicity analyses	9
Nano-liposomal zein hydrolysate for improved apoptotic activity and therapeutic index in lung cancer treatment	9
Tumor-derived extracellular vesicles for the active targeting and effective treatment of colorectal tumors in vivo	9