OOIR: Observatory of International Research

Papers

(The median citation count of Free Radical Research is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Role of oxidative stress in nanoparticles toxicity	119
Ferroptosis and cardiovascular disease: role of free radical-induced lipid peroxidation	82
Protein carbonylation: molecular mechanisms, biological implications, and analytical approaches	66
Understanding the antioxidant and carbonyl sequestering activity of carnosine: direct and indirect mechanisms	55
On the relevance of hydroxyl radical to purine DNA damage	49
MicroRNA-1287-5p promotes ferroptosis of osteosarcoma cells through inhibiting GPX4	44
MicroRNA-670-3p suppresses ferroptosis of human glioblastoma cells through targeting ACSL4	40
Erythrocytes as a preferential target of oxidative stress in blood	33
MicroRNA-302a-3p induces ferroptosis of non-small cell lung cancer cells via targeting ferroportin	31
Recent advances in the antioxidant activity and mechanisms of chalcone derivatives: a computational review	30
Reactive oxygen species: the root cause of nanoparticle-induced toxicity in Drosophila melanogaster	29
Antioxidant action of vitamin Ein vivoas assessed from its reaction products with multiple biological oxidants	24
4-Hydroxy-2-nonenal, a lipid peroxidation product, as a biomarker in diabetes and its complications: challenges and opportunities	24
G6PD deficiency, redox homeostasis, and viral infections: implications for SARS-CoV-2 (COVID-19)	24
Melatonin alleviates hydrogen peroxide induced oxidative damage in MC3T3-E1 cells and promotes osteogenesis by activating SIRT1	21
SARS-CoV-2 induces mitochondrial dysfunction and cell death by oxidative stress/inflammation in leukocytes of COVID-19 patients	19
Feedback of hypoxia-inducible factor-1alpha (HIF-1alpha) transcriptional activity via redox factor-1 (Ref-1) induction by reactive oxygen species (ROS)	19
Recent advances in iron homeostasis and regulation - a focus on epigenetic regulation and stroke	17
Gasotransmitter signaling in energy homeostasis and metabolic disorders	17
Activation of DNA damage response signaling in mammalian cells by ionizing radiation	17
Iron metabolism: an emerging therapeutic target underlying the anti-cancer effect of quercetin	15
Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells	15
Uranium induces kidney cells pyroptosis in culture involved in ROS/NLRP3/caspase-1 signaling	15
Antioxidant action of persulfides and polysulfides against free radical-mediated lipid peroxidation	15
Proportional coexistence of okanin chalcone glycoside and okanin flavanone glycoside inBidens pilosaleaves and theoretical investigation on the antioxidant properties of their aglycones	15

Autoxidation and photooxidation of tetrahydrobiopterin: a theoretical study	15
The mitochondrial antioxidant SS-31 attenuated lipopolysaccharide-induced apoptosis and pyroptosis of nucleus pulposus cells via scavenging mitochondrial ROS and maintaining the stability of mitochond	15
Redox reactions of organoselenium compounds: Implication in their biological activity	14
The effect of a color tattoo on the local skin redox regulatory network: an N-of-1 study	14
Chemical and biological basis for development of novel radioprotective drugs for cancer therapy	14
MicroRNA-217 modulates inflammation, oxidative stress, and lung injury in septic mice via SIRT1	13
An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by β-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChR-mediated signalling	12
Implication of mitochondrial ROS-NLRP3 inflammasome axis during two-hit mediated acute lung injury in mice	12
Lipid composition dictates the rate of lipid peroxidation in artificial lipid droplets	12
Hydroperoxyl radical (HOO^•) as a reducing agent: unexpected synergy with antioxidants. A review	11
Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress	11
Comparison of three methods for in vivo quantification of glutathione in tissues of hypertensive rats	11
Quercetin-3-rutinoside protects against gamma radiation inflicted hematopoietic dysfunction by regulating oxidative, inflammatory, and apoptotic mediators in mouse spleen and bone marrow	10
Autism spectrum disorder (ASD)-associated mitochondrial deficits are revealed in children’s platelets but unimproved by hyperbaric oxygen therapy	10
Heavy-ion beam-induced reactive oxygen species and redox reactions	10
Valproic acid promotes SOD2 acetylation: a potential mechanism of valproic acid-induced oxidative stress in developing systems	10
MicroRNA-328-3p facilitates the progression of gastric cancer via KEAP1/NRF2 axis	10
MicroRNA-499-5p targets SIRT1 to aggravate lipopolysaccharide-induced acute lung injury	10
HIF-1α protects osteoblasts from ROS-induced apoptosis	10
In vitro analysis of catalase and superoxide dismutase mimetic properties of blue tattoo ink	10
Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment	9
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway	9
Hypoxia induces proliferation via NOX4-Mediated oxidative stress and TGF-β3 signaling in uterine leiomyoma cells	9
Oxidative stress and gender disparity in cancer	9
Growth differentiation factor 11 mitigates cardiac radiotoxicity via activating AMPKα	9
The role of miR-199b-3p in regulating Nrf2 pathway by dihydromyricetin to alleviate septic acute kidney injury	9
Glutathione peroxidase 2 (Gpx2) preserves mitochondrial function and decreases ROS levels in chronologically aged yeast	9
Serum superoxide dismutase activity: a sensitive, convenient, and economical indicator associated with the prevalence of chronic type 2 diabetic complications, especially in men	8
Detection and structural analysis of lipid-derived radicals in vitro and in vivo	8
Free radical scavenging activity of gallic acid toward various reactive oxygen, nitrogen, and sulfur species: a DFT approach	8
A new mitochondrial probe combining pyrene and a triphenylphosphonium salt for cellular oxygen and free radical detection via fluorescence lifetime measurements	8
Cold atmospheric plasma-induced oxidative stress and ensuing immunological response – a Neo-Vista in immunotherapy	7
Generation and measurement of low-temperature plasma for cancer therapy: a historical review	7
Antioxidant and prooxidant modulation of lipid peroxidation by integral membrane proteins	7
Cross-talk between TRPC-1, mTOR, PGC-1α and PPARδ in the dystrophic muscle cells treated with tempol	7
Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: biochemical and histopathological evidence	7
Melatonin improves the antioxidant capacity in cardiac tissue of Wistar rats after exhaustive exercise	7
Adsorption of free radical TEMPO onto Al₂O₃ nanoparticles and evaluation of radical scavenging activity	7
Electrophilic oxysterols: generation, measurement and protein modification	6
Impact of eugenol onin vivomodel of 6-hydroxydopamine-induced oxidative stress	6
The radical scavenger capacity and mechanism of prenylated coumestan-type compounds: a DFT analysis	6
Theoretical insights into the radical scavenging activity of glipizide: DFT and molecular docking studies	6
Phenotypic characterization of circulating endothelial cells induced by inflammation and oxidative stress in ankylosing spondylitis	6
Antioxidant activity of caffeic acid: thermodynamic and kinetic aspects on the oxidative degradation pathway	6
Lactobacillus brevis MTCC 1750 enhances oxidative stress resistance and lifespan extension with improved physiological and functional capacity in Caenorhabditis elegans via the DAF-16 pa	6
Exercise associated with γ-oryzanol supplementation suppresses oxidative stress and prevents changes in locomotion in Drosophila melanogaster	6
Trafficking of oxidative stress-generated lipid hydroperoxides: pathophysiological implications	6
Andrographolide attenuates sepsis-induced acute kidney injury by inhibiting ferroptosis through the Nrf2/FSP1 pathway	6
Metabolomics analysis of the effects of quercetin on hepatotoxicity induced by acrylamide exposure in rats	5
Antioxidant activity of erlotinib and gefitinib: theoretical and experimental insights	5

Relationship between hemodynamic alteration and sympathetic nerve activation following a single oral dose of cinnamtannin A2	5
Deoxyarbutin attenuates severe acute pancreatitis via the HtrA2/PGC-1α pathway	5
Betulinic acid mitigates oxidative stress-mediated apoptosis and enhances longevity in the yeast Saccharomyces cerevisiae model	5
Mitochondrial bioenergetics and enzymatic antioxidant defense differ in Paraná pine cell lines with contrasting embryogenic potential	5
Role of oxidative stress in induction of trans-differentiation of neutrophils in patients with rheumatoid arthritis	5
The microbiota catabolites of quercetin glycosides concertedly enhance the resistance against acetaldehyde-induced oxidative stress	5
Graphene oxide nanoflakes prevent reperfusion injury of Langendorff isolated rat heart providing antioxidative activity in situ	5
Cancer-specific cytotoxicity of Ringer’s acetate solution irradiated by cold atmospheric pressure plasma	5
Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds	4
Effects of LET on oxygen-dependent and-independent generation of hydrogen peroxide in water irradiated by carbon-ion beams	4
Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric ca	4
Flavoenzyme-catalyzed single-electron reduction of nitroaromatic antiandrogens: implications for their cytotoxicity	4
CD36 down regulation by the macrophage antioxidant 7,8-dihydroneopterin through modulation of PPAR-γ activity	4
Molecular and biochemical investigations of inborn errors of metabolism-altered redox homeostasis in branched-chain amino acid disorders, organic acidurias, and homocystinuria	4
Renoprotective effect of esculetin against ischemic acute kidney injury-diabetic comorbidity	4
The effects of nitric oxide or oxygen on the stable products formed from the tyrosine phenoxyl radical	4
Changes in tumor suppressors and inflammatory responses during hydrogen peroxide-induced senescence in rat fibroblasts	4
In-gel SOD assay reveals SOD-2 is the single active, water-soluble SOD enzyme in C. elegans	4
Thermodynamic and kinetic studies on antioxidant capacity of amentoflavone: a DFT (density functional theory) computational approach	4
Protective effect of ebselen on bleomycin-induced lung fibrosis: analysis of the molecular mechanism of lung fibrosis mediated by oxidized diacylglycerol	4
Dissecting the potential role of ferroptosis in liver diseases: an updated review	4
MiR-125b-5p is targeted by curcumin to regulate the cellular antioxidant capacity	4
Distribution and quantitative analysis of homoanserine and its 2-oxo derivative in mouse tissues	4
FeTMPyP a peroxynitrite decomposition catalyst ameliorated functional and behavioral deficits in chronic constriction injury induced neuropathic pain in rats	4
Modulation of reactive oxygen species in cancers: recent advances	4
Circadian rhythm and time-of-day-effects of (anti)oxidant biomarkers for epidemiological studies	4
Current understanding of plasma-activated solutions for potential cancer therapy	4
VDR promotes nucleus pulposus cell mitophagy as a protective mechanism against oxidative stress injury	4
Low-temperature plasma as magic wand to differentiate between the good and the evil	4
Recent advances in the antioxidant activity of metal-curcumin complexes: a combined computational and experimental review	4
Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH	4
Metabolomics analysis of the effects of quercetin on Cd-induced hepatotoxicityin rats	4
Febuxostat reduces muscle wasting in tumor-bearing mice with LM8 osteosarcoma cells via inhibition of reactive oxygen species generation	4
Redox interactions of immune cells and muscle in the regulation of exercise-induced pain and analgesia: implications on the modulation of muscle nociceptor sensory neurons	4
Guaiacol oxidation: theoretical insight into thermochemistry of radical processes involving methoxy group demethylation	3
Retrograde response to mitochondrial dysfunctions associated to LOF variations in FLAD1 exon 2: unraveling the importance of RFVT2	3
Increased production of 8-oxo-7,8-dihydroguanine in human urine, a novel biomarker of osteoporosis	3
Potential role of free-radical processes in biomolecules damage during COVID-19 and ways of their regulation	3
Superoxide dismutase and glutathione peroxidase activities in a population exposed to high indoor radon concentration: a preliminary report	3
Pharmacological inhibition of SIRT-2 by AK-7 modulates redox status and apoptosis via regulating Nrf2 in an experimental model of chronic obstructive pulmonary disease: an invivo and insilico study	3
Targeting endogenous gaseous signaling molecules as novel host-directed therapies against tuberculosis infection	3
Transferrin-mediated increase of labile iron Pool following simulated ischemia causes lipid peroxidation during the early phase of reperfusion	3
Defense systems to avoid ferroptosis caused by lipid peroxidation-mediated membrane damage	3
Near-infrared Nrf2 activator IR-61 dye alleviates radiation-induced lung injury	3
Non-thermal plasma elicits ferrous chloride-catalyzed DMPO-OH	3
Silver nanoparticles-induced H₂O₂ triggers apoptosis-like death and is associated with dinF in Escherichia coli	3
Mitochondrial targeted ROS scavenger based on nitroxide for treatment and MRI imaging of acute kidney injury	3
Alpha-synuclein interaction with mitochondria is the final mechanism of ferroptotic death induced by erastin in SH-SY5Y cells	3
Combined action of FOXO1 and superoxide dismutase 3 promotes MDA-MB-231 cell migration	3
A potential screening method for epigenetic drugs: uncovering stress-induced gene silencing in Chlamydomonas	3
Can the iron content of culture media impact on the leishmanicidal effect of artemisinin?	3
The downregulation of NADPH oxidase Nox4 during hypoxia in hemangioendothelioma cells: a possible role of p22^phox on Nox4 protein stability	3
A novel tin based hydroxamic acid complex induces apoptosis through redox imbalance and targets Stat3/JNK1/MMP axis to overcome drug resistance in cancer	3
Tetrachloroaurate (III)-induced oxidation increases non-thermal plasma-induced oxidative stress	3