OOIR: Observatory of International Research

Papers

(The TQCC of In Vitro Cellular & Developmental Biology-Animal is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The origins of human pluripotent stem cells: the road from a cancer to regenerative medicine	45
DHA attenuates cartilage degeneration by mediating apoptosis and autophagy in human chondrocytes and rat models of osteoarthritis	33
Index	29
Comparative effect of goat and fetal bovine serum on goat muscle stem cell proliferation in vitro	24
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway	22
Neuroprotective effect of Saikogenin F on corticosterone-induced cytotoxicity in PC12 cells involves P2X7R-NLRP3 and cAMP-PKA pathways	21
Ghrelin inhibits NLRP3 inflammasome activation by upregulating autophagy to improve Alzheimer’s disease	20
Dexmedetomidine preserves neuronal function by promoting mitochondrial biogenesis through the AMPK/PGC-1α pathway	17
BMSC-derived exosomes regulate the Treg/Th17 balance through the miR-21-5p/TLR4/MyD88/NF-κB pathway to alleviate dry eye symptoms in mice	16
Coating materials enhance urochordate primary cell culture adherence	15
Mechanical regulation of N2A neural cell behavior by microtissue densification	15
Dihydrocapsaicin suppresses the migration and invasion of gastric cancer cells by upregulating TRPV1 expression	14
Endothelial cell-derived microRNAs-containing extracellular vesicles and diabetic retinopathy in a mouse model of diabetes	14
A comparative genotoxicity study of agrochemicals: nuclear abnormalities, comet assay, and gene expression alterations	13
Bringing cell biology into classroom: tips to culture and observe skeletal muscle cells in high school and college	13
Establishment of human embryonic stem cell line expressing EGFP reporter driven by human RAX promoter for evaluation of retinal progenitor cell potency	13
PRRX1 upregulates PD-L1 in human mesenchymal stem cells	13
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma	13
A cell line derived from the black soldier fly, Hermetia illucens (Diptera: Stratiomyidae)	13
Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs	12
Effects of centrifugation treatment before electroporation on gene editing in pig embryos	12
Differentiation of human endometrial mesenchymal cells to epithelial and stromal cells by seeding on the decellularized endometrial scaffold	12
MOF promotes cisplatin resistance in lung cancer cells by enhancing WSTF acetylation	11
Synergistic effects of micropatterned substrates and transforming growth factor-β1 on differentiation of human mesenchymal stem cells into vascular smooth muscle cells through modulation of Krϋppel-li	11
The protective effects of antioxidants against endogenous and exogenous oxidative stress on bull sperm	11

Liposome-iRGD loaded with astragaloside IV alleviates the functional damage of endothelial progenitor cells via the Hippo-YAP/TAZ signaling pathway	11
2-Aminoethoxydiphenyl borate induces arrhythmias via Cx43-S282 dephosphorylation	10
Effects of nylon mesh vitrification on the cytoskeleton, mitochondria, and aquaporins of mouse 2-cell embryos	10
KHDRBS3-mediated upregulation of circ_0024107 in gastric cancer cells and GC-MSCs synergistically drives gastric cancer cell migration and invasion	10
Optimization of a protocol for the high-yield isolation of active muscle stem cells from bovine skeletal muscle tissue	10
Establishment and characterization of a novel kidney cell line derived from the common bottlenose dolphin	10
Correction: The effects of carbon-ion beam irradiation on three-dimensional in vitro models of normal oral mucosa and oral cancer: development of a novel tool to evaluate cancer therapy	9
Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy	9
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish (Danio rerio) cell models	9
The combination of neurotropic B vitamins (B1, B6, and B12) is superior to individual B vitamins in promoting neurite growth in vitro	8
Nanoscale vibration could promote tenogenic differentiation of umbilical cord mesenchymal stem cells	8
Resolvin D1 suppresses inflammation in human fibroblast-like synoviocytes via the p-38, NF-κB, and AKT signaling pathways	8
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning	8
MiR-21-5p promotes RPE cell necroptosis by targeting Peli1 in a rat model of AMD	8
Macrophage pyroptosis promotes synovial fibrosis through the HMGB1/TGF- β1 axis: an in vivo and in vitro study	8
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells	7
The abnormal thyroxine signals triggers podocyte apoptosis in DN mice	7
Direct reprogramming of Müller glia into photoreceptors via multiple transcription factors and small molecules: molecular mechanisms and transcriptomic analysis	7
Efficacy determination of a disinfectant against channel catfish virus by in vitro and in vivo methods	7
Compatibility of Calycosin-Tanshinone IIA improves Ang II-induced renal artery endothelial cell dysfunction through lncRNA-mRNA co-expression network	7
miR-155-5p can be involved in acquisition of osseointegration on titanium surface	7
Plant Posters	7
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs	7
Characterization and arbovirus susceptibility of cultured CERNI cells derived from sika deer (Cervus nippon)	7
Serotype-specific effects of adenovirus 5 and 52 E4ORF1 proteins on endothelial cell-mediated regulation of hematopoietic stem cell expansion and lineage differentiation	6
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action: comment	6
The adaptation of bovine embryonic stem cells to the changes of feeder layers	6
Production of MSTN knockout porcine cells using adenine base-editing-mediated exon skipping	6
Paclitaxel-induced cytoskeletal and focal adhesion reorganisation alters connexin43 and α-smooth muscle actin in cardiac cells	6
Prevalence of cyprinid herpesvirus-2 in goldfish aquarium shops in Tamil Nadu, India: a case report	6
Establishment, characterization, and sensory characteristics (taste and flavor) of an immortalized muscle cell line from the seven-band grouper Epinephelus septemfasciatus: implications for cultured s	6
Ginsenoside Rg1 treats chronic heart failure by downregulating ERK1/2 protein phosphorylation	6
Knockdown of Chk1 inhibits proliferation and promotes apoptosis in mouse granulosa cells and its regulation mechanism by miR-15a and miR-16	6
Cathepsin K degrades osteoprotegerin to promote osteoclastogenesis in vitro	6
Joint Symposium	6
Pluripotent cells derived from 50% epiboly zebrafish embryos	6
2025 Special Reviewers Thank You	6
Ginsenoside Rg1 mitigates myocardial ischemia/reperfusion injury by inhibiting NLRP3-mediated pyroptosis	6
Liver organoids cocultured on decellularized native liver scaffolds as a bridging therapy improves survival from liver failure in rabbits	6
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models	6
Study on the mechanism of SAR1B in sodium acetate promoting milk fat synthesis	6
Overexpression of long non‑coding RNA H19 enhances cell viability and inhibits apoptosis in recurrent spontaneous abortion by targeting the miR-29a-3p/SOCS3 axis	6
NEURL1 acts as a candidate suppressor in bladder cancer by down-regulating PDE9A	6
Animal Contributed Papers	5
miR-106b enhances human mesenchymal stem cell differentiation to spermatogonial stem cells under germ cell profile genes involved in TGF-b signaling pathways	5
Wnt signaling in cardiac development and heart diseases	5
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway	5
Novel use of a − 20°C cryoprotectant yields high viability and improved aggregation of marine sponge cells	5
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies	5
Dentin matrix protein-1 promoted osteogenic differentiation of valvular interstitial cells via MAPK signal pathway during aortic valve calcification	5

ATF4 regulates PI3K/AKT signaling axis to promote angiogenesis after myocardial infarction	5
α-Cyperone affects the development and chemosensitivity of breast cancer by modulating TRIM24	5
Xuebijing inhibits alveolar macrophage M1 polarization by regulating ROS-mediated NLRP3 inflammasome signaling	5
Animal Symposia and Workshops	5
JAML inhibits colorectal carcinogenesis by modulating the tumor immune microenvironment	5
The active ingredient of Ginkgo biloba extract (quercetin) improved H2O2-induced microglia injury by activating NQO1-PI3K/Akt/mTOR signaling	5
Exosomal miR-590-3p derived from bone marrow mesenchymal stem cells promotes osteoblast differentiation and osteogenesis by targeting TGFBR1	5
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis	5
Generation of allogenic chimera carrying mutations in PDX1 and TP53 genes via phytohemagglutinin-mediated blastomere aggregation in pigs	5
Secukinumab plays a synergistic role with starvation therapy in promoting autophagic cell death of hepatocellular carcinoma via inhibiting IL-17A-increased BCL2 level	5
Strongylopus grayii tadpole blastema extract exerts cytotoxic effects on embryonal rhabdomyosarcoma cells	5
IL-17A inhibits the degradation of RANKL in osteoblasts by inhibiting BCL2-Beclin1-autophagy signaling	5
Impact and mechanism of the TBX-22 gene mutation G874A on the epithelial-mesenchymal transition in medial edge epithelial cells	5
Plant Symposia and Workshops	5
Advancing marine invertebrate cell line research: four key knowledge gaps	5
Ulinastatin ameliorates podocyte ferroptosis via regulating miR-144-3p/SLC7A11 axis in acute kidney injury	5
SERPINA3 is expressed in human adipocytes and modulated by TNF-α and vitamin B6	5
Transfection, cytotoxicity, and cell cycle studies on the two newly developed and characterized humpback grouper (Cromileptes altivelis) fin cell lines	5
Impact of repeated intravenous infusions of umbilical cord–derived versus bone marrow–derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat mod	5
Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake	4
DDX3 inhibits PTZ-induced ferroptosis in human neuronal SH-SY5Y cells via Wnt/β-catenin signaling	4
Role of Mydgf in the regulation of hypoxia/reoxygenation-induced apoptosis in cardiac microvascular endothelial cells	4
Myricetin ameliorates the IL-21-induced tumorigenic phenotype of adjuvant-induced arthritis FLS by modulating the choline kinase signaling cascade	4
PTIP inhibits proliferation, migration, and angiogenesis of retinal microvascular endothelial cells in a high-glucose environment	4
Wogonin improves high glucose-induced ARPE-19 cell damage by inhibiting ferroptosis via suppressing the cGAS-STING pathway	4
Therapeutic targeting of Nrf2/HO-1/NF-κB signaling axis with casticin mitigates intervertebral disc degeneration: in vitro and in vivo investigations	4
Taurine promotes insulin synthesis by enhancing Isl-1 expression through miR-7a/RAF1/ERK1/2 pathway	4
Human embryonic stem cells maintain their stemness in three-dimensional microenvironment	4
2023 Special Reviewers Thank You	4
Cadmium-induced nucleus pulposus derived mesenchymal stem cells apoptosis via MAPK signaling pathway contributes to IVD degeneration	4
In vitro inhibitory effect of zingerone on TNFα-stimulated fibroblast-like synoviocytes	4
Transcription factor HOXA4 promotes HBV replication and hepatocellular carcinoma proliferation by activating KIF11 transcription	4
Reduced myogenic differentiation capacity of satellite cell-derived myoblasts in male ICR mice compared with male C57BL/6 and BALB/c mice	4
Photobiomodulation therapy: a promising treatment for insulin resistance in type 2 diabetes	4
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers	4
Liriodendrin stimulates proliferation and milk protein synthesis of mammary epithelial cells via the PI3K-DDX18 signaling	4
SPARC: a key mediator of apoptosis in human umbilical vein endothelial cells and its role in hypertension mechanism	4
TRIM9 promotes Müller cell–derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7	4
Development and characterization of primary cell culture from the spinal cord of Asian seabass, Lates calcarifer	4
Distinguishing between ante factum and post factum properties of animal cell lines and demonstrating their use in grouping ray-finned fish cell lines into invitromes	4
Tumor endothelial cell-derived Sfrp1 supports the maintenance of cancer stem cells via Wnt signaling	4
Reprogramming cultured human fungiform (HBO) taste cells into neuron-like cells through in vitro induction	4
mTORC1 signalling and protein synthesis are elevated in response to amino acids in human myotubes obtained from young, old, and old trained men	4
Establishment and characterization of novel spontaneously immortalized larval cell lines from sablefish Anoplopoma fimbria	4
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose	4
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis	4
16th International Conference on Invertebrate and Fish Cell Culture	4
In vitro replication efficiency of tilapia parvovirus (TiPV) using different fish cell lines	4
LINC01224 promotes the Warburg effect in gastric cancer by activating the miR-486-5p/PI3K axis	4
Arf1 promotes porcine intestinal epithelial cell proliferation via the mTORC1 signaling pathway	4
SIVB’s 2024 In Vitro Biology Meeting: Program, Schedule, Awards, and Acknowledgements	4
Construction of tissue-engineered vascular sinoatrial node in vitro	4
RMI2 knockdown suppresses ovarian cancer cell growth by impairing DNA damage repair via the ATR/CHK1 signaling pathway	4
Education Posters	4
Overexpression of MEOX2 inhibits breast cancer cell metastasis by targeting oxidative stress-induced RGS5	4
Ginsenoside Rg1 relieves rat intervertebral disc degeneration and inhibits IL-1β-induced nucleus pulposus cell apoptosis and inflammation via NF-κB signaling pathway	4
Low expression of miR-1929-3p mediates murine cytomegalovirus-induced fibrosis in cardiac fibroblasts via targeting endothelin a receptor/NLRP3 inflammasome pathway	4