OOIR: Observatory of International Research

Papers

(The TQCC of Wound Repair and Regeneration is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Chronic wounds: Treatment consensus	152
Fibroblast‐like synoviocytes: Role in synovial fibrosis associated with osteoarthritis	60
Diabetic wound healing: The impact of diabetes on myofibroblast activity and its potential therapeutic treatments	55
Myofibroblast progeny in wound biology and wound healing studies	46
Monocyte and macrophage derived myofibroblasts: Is it fate? A review of the current evidence	43
Pullulan‐Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings	39
Vimentin regulates the assembly and function of matrix adhesions	33
Stem cell‐mediated angiogenesis in skin tissue engineering and wound healing	33
Granulation tissue myofibroblasts during normal and pathological skin healing: The interaction between their secretome and the microenvironment	30
What is the “normal” wound bed temperature? A scoping review and new hypothesis	26
Antibiofilm activity of chitosan/epsilon‐poly‐L‐lysine hydrogels in a porcine ex vivo skin wound polymicrobial biofilm model	25
Myofibroblast fate plasticity in tissue repair and fibrosis: Deactivation, apoptosis, senescence and reprogramming	25
Prophylactic dressings in the prevention of pressure ulcer related to the use of personal protective equipment by health professionals facing the COVID‐19 pandemic: A randomized clinical trial	24
Is there an association between anemia and diabetic foot ulcers? A systematic review and meta‐analysis	22
A story of fibers and stress: Matrix‐embedded signals for fibroblast activation in the skin	21
LncRNA HOTAIR modulates chondrocyte apoptosis and inflammation in osteoarthritis via regulating miR‐1277‐5p/SGTB axis	21
Evaluation of LL‐37 in healing of hard‐to‐heal venous leg ulcers: A multicentric prospective randomized placebo‐controlled clinical trial	20
A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimic	19
Analyzing factors affecting quality of life in patients hospitalized with chronic wound	19
Food and Drug Administration perspective: Advancing product development for non‐healing chronic wounds	19
Assessment of a smartphone‐based application for diabetic foot ulcer measurement	18
Effects of physical activity as an adjunct treatment on healing outcomes and recurrence of venous leg ulcers: A scoping review	17
Analysis of HOX gene expression and the effects of HOXA9 overexpression in fibroblasts derived from keloid lesions and normal skin	16
The hard problem: Mechanotransduction perpetuates the myofibroblast phenotype in scleroderma fibrosis	15
Gene therapy in wound healing using nanotechnology	15

Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells	15
Assessing the quality of life of people with chronic wounds by using the cross‐culturally valid and revised Wound‐QoL questionnaire	15
Pyoderma gangrenosum study pilot registry: The first step to a better understanding	15
Evidence supporting wound care end points relevant to clinical practice and patients' lives. Part 3: The Patient Survey	15
The role of negative pressure wound therapy (NPWT) on the treatment of pyoderma gangrenosum: A systematic review and personal experience	14
Silk proteins in reconstructive surgery: Do they possess an inherent antibacterial activity? A systematic review	14
Novel factors that activate and deactivate cardiac fibroblasts: A new perspective for treatment of cardiac fibrosis	14
Association of vaping with decreased vascular endothelial growth factor expression and decreased microvessel density in cutaneous wound healing tissue in rats	14
Growth factors for treating chronic venous leg ulcers: A systematic review and meta‐analysis	14
Evaluation of contraction of the split‐thickness skin graft using three dermal matrices in the treatment of burn contractures: A randomised clinical trial	13
Quality‐of‐life of people with keloids and its correlation with clinical severity and demographic profiles	13
To compare the effect of sea buckthorn and silver sulfadiazine dressing on period of wound healing in patients with second‐degree burns: A randomized triple‐blind clinical trial	13
Bromelain‐based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial	13
APACHE scoring system and pressure injury risk for intensive care patients: A systematic review and meta‐analysis	13
To regenerate or not to regenerate: Vertebrate model organisms of regeneration‐competency and ‐incompetency	13
Photoacoustic monitoring of angiogenesis predicts response to therapy in healing wounds	13
HCN2 channel‐induced rescue of brain, eye, heart and gut teratogenesis caused by nicotine, ethanol and aberrant notch signalling	13
Bacterial protease activity as a biomarker to assess the risk of non‐healing in chronic wounds: Results from a multicentre prospective cohort clinical trial	13
Keloid tissue analysis discredits a role for myofibroblasts in disease pathogenesis	13
Poly(lactide‐co‐ε‐caprolactone) scaffold promotes equivalent tissue integration and supports skin grafts compared to a predicate collagen scaffold	12
The pig as a model system for investigating the recruitment and contribution of myofibroblasts in skin healing	12
Effects of platelet‐rich plasma on the healing of sternal wounds: A meta‐analysis	12
Bacteria and bioburden and healing in complex wounds: A prognostic systematic review	12
Animal models for the study of acute cutaneous wound healing	12
Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration	12
Effectiveness of a synthetic human recombinant epidermal growth factor in diabetic patients wound healing: Pilot, double‐blind, randomized clinical con	11
Current applications of platelet gels in wound healing—A review	11
Valsartan nano‐filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds	11
Further evidence that wound size and duration are strong prognostic markers of diabetic foot ulcer healing	11
The modulation of the burn wound environment by negative pressure wound therapy: Insights from the proteome	11
Integrin α4β1 is required for IL‐1α‐ and Nrf2‐dependent, Cox‐2 induction in fibroblasts, supporting a mechanism that suppresses α‐SMA expression	10
Recent advances in the induced pluripotent stem cell‐based skin regeneration	10
LncRNA MIR503HG promotes hypertrophic scar progression via miR‐143‐3p‐mediated Smad3 expression	10
Hyperbaric oxygen therapy for nonhealing wounds: Treatment results of a single center	10
Comparing the effects of three different multilayer dressings for pressure ulcer prevention on sacral skin after prolonged loading: An exploratory crossover trial	10
Scar quality in children with burns 5–7 years after injury: A cross‐sectional multicentre study	9
Autologous thrombin preparations: Biocompatibility and growth factor release	9
Incidence of and risk factors for self‐load‐related and medical device‐related pressure injuries in critically ill patients: A prospective observational cohort study	9
Dissolved oxygen technologies as a novel strategy for non‐healing wounds: A critical review	9
Investigating quality of life instrument measurement properties for adults with active venous leg ulcers: A systematic review	9
The surgical approach to Pyoderma gangrenosum: A retrospective monocenter study	9
Pulsed dye laser versus ablative fractional CO₂ laser in treatment of old hypertrophic scars: Clinicopathological study	9
The role of bacterial extracellular vesicles in chronic wound infections: Current knowledge and future challenges	9
Matrix metalloproteinase (MMP)‐1 and MMP‐2, but not COX‐2 serve as additional predictors for chronic venous ulcer healing	9
Progress in copper‐based materials for wound healing	9
Using systems biology approaches to identify signalling pathways activated during chronic wound initiation	8
Wound fluid sampling methods for proteomic studies: A scoping review	8
Efficacy and safety of skin grafting in treatment of vasculitic ulcer and pyoderma gangrenosum—A systematic review	8
Reactive oxygen species during heart regeneration in zebrafish: Lessons for future clinical therapies	8
Cellular benefits of single‐use negative pressure wound therapy demonstrated in a novel ex vivo human skin wound model	7

WHS (Wound Healing Society) guidelines update: Diabetic foot ulcer treatment guidelines	7
Evaluation of foot ulcer incidence in diabetic patients at a diabetic foot ulcer prevention clinic over a 10‐year period	7
The wound healing effect of local leukocyte platelet‐rich plasma after total hip arthroplasty: A randomized controlled trial	7
Biomimetic analyses of interactions between macrophages and palmar fascia myofibroblasts derived from Dupuytren's disease reveal distinct inflammatory cytokine responses	7
WHS guidelines for the treatment of pressure ulcers—2023 update	7
The lysophosphatidic acid axis in fibrosis: Implications for glaucoma	7
Animal experimental models of ischemic wounds – A review of literature	7
Engineered microenvironment for the study of myofibroblast mechanobiology	7
Autologous platelet‐rich fibrin as an adjunct to non‐surgical periodontal therapy—A follow up clinical pilot study	7
Topically administered purified clinoptilolite‐tuff for the treatment of cutaneous wounds: A prospective, randomised phase I clinical trial	7
Fibrosis: Sirtuins at the checkpoints of myofibroblast differentiation and profibrotic activity	7
Use of a negative pressure wound therapy system over closed incisions option in preventing post‐sternotomy wound complications	6
Tissue‐mimetic culture enhances mesenchymal stem cell secretome capacity to improve regenerative activity of keratinocytes and fibroblasts in vitro	6
Insights into the skin microbiome of sickle cell disease leg ulcers	6
PI3K/AKT pathway promotes keloid fibroblasts proliferation by enhancing glycolysis under hypoxia	6
Does vitamin D deficiency predispose to keloids via dysregulation of koebnerisin (S100A15)? A case‐control study	6
Cell‐free therapy based on stem cell‐derived exosomes: A promising approach for wound healing	6
Friction characteristics of preventative wound dressings under clinically‐relevant conditions	6
The myofibroblast and Giulio Gabbiani: An inseparable couple celebrates their 50 years golden wedding anniversary	6
Factors influencing lower extremity amputation outcomes in people with active foot ulceration in regional Australia: A retrospective cohort study	6
A molecular approach to maggot debridement therapy with Lucilia sericata and its excretions/secretions in wound healing	6
The Danish wound‐quality of life (Wound‐QoL) questionnaire: Translation and psychometric properties	6
Knockout of sodium channel Na_x delays re‐epithelializathion of splinted murine excisional wounds	6
Antimicrobial peptide derived from insulin‐like growth factor‐binding protein 5 improves diabetic wound healing	6
Gout‐associated uric acid crystals induce tophi ulcerations and impair wound healing in a novel gouty ulcer model	6